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JOURNAL ARTICLE
Usman Mir Khan, Aysha Sameen, Eric Andrew Decker, Muhammad Asim Shabbir, Shahzad Hussain, Anam Latif, Gholamreza Abdi, Rana Muhammad Aadil
Plant extracts have demonstrated the ability to act as coagulants for milk coagulation at an adequate concentration, wide temperatures and pH ranges. This research is focused on the use of different vegetative extracts such as Citrus aurnatium flower extract (CAFE), bromelain, fig latex, and melon extract as economical and beneficial coagulants in the development of plant-based cheddar-type cheese. The cheddar-type cheese samples were subjected to physicochemical analysis in comparison to controlled cheese samples made from acetic acid and rennet...
June 30, 2024: Food chemistry: X
#22
JOURNAL ARTICLE
Arshad Farid, Mahrukh Mehraj, Susmita Das, Fathima Feroz, Ab Waheed Wani, S Q Dar, Sanjeev Kumar, Atif Khurshid Wani
Pineapple (Ananas comosus), the succulent and vibrant tropical fruit, is a symbol of exoticism and sweetness. The pineapple peel, often considered as waste, has garnered attention for its potential applications. The pineapple peel is rich in essential nutrients, including calcium, potassium, vitamin C, carbohydrates, dietary fiber, and water, making it beneficial for the digestive system, weight management, and overall balanced nutrition. It contains significant amounts of sugars such as sucrose, glucose, and fructose, along with citric acid as the predominant organic acid...
March 14, 2024: Chemistry & Biodiversity
#23
JOURNAL ARTICLE
Lidia Rodríguez-Ortiz, Mari C Vázquez-Borrego, Florina I Bura, Melissa Granados-Rodríguez, Francisca Valenzuela-Molina, Blanca Rufián-Andújar, Ana Martínez-López, Rosa Ortega-Salas, Juan José Espejo-Herrero, Antonio Romero-Ruiz, Álvaro Arjona-Sánchez
No abstract text is available yet for this article.
March 2, 2024: British Journal of Surgery
#24
JOURNAL ARTICLE
Farahnaz Sharafeddin, Zahra Jowkar, Mina Safari
BACKGROUND: The dentin substrate can be modified by proteolytic agents, which may affect the bonding strength of adhesive systems to the treated dentin surface. Papain, a cysteine protease enzyme with antibacterial and anti-inflammatory properties, can be used for deproteinization of dentin. An alternative deproteinizing enzyme is bromelain. OBJECTIVES: This study aimed to evaluate the impact of deproteinization on the shear bond strength (SBS) of composite resin to deep dentin using different concentrations of bromelain and papain...
2024: Dental and Medical Problems
#25
JOURNAL ARTICLE
Kosar Gharib-Naseri, Sarbast K Kheravii, Hong Thi Nguyen, Shu-Biao Wu
This study was conducted to examine the efficacy of a bromelain-based supplementation coded ANR-pf on growth performance and intestinal lesion of broiler chickens under necrotic enteritis (NE) challenge. A total of 540 Ross 308 day-old male chicks were randomly allocated into 6 treatments of 6 replicates. The bromelain formulation was delivered to chickens through gavaging or in drinking water method twice, on d 8 and 13. Nonchallenged groups included 1) without or 2) with the specific bromelain formulation gavaged at 0...
February 16, 2024: Poultry Science
#26
JOURNAL ARTICLE
Giuseppe Consorti, Gabriele Monarchi, Mariagrazia Paglianiti, Enrico Betti, Paolo Balercia
Background: Bromelain and coumarins are recognized as safe and effective therapeutic agents, used by individuals to treat ailments such as postoperative edema, inflammation and other diseases. Bromelain has been proven to be well absorbed by the body after oral administration, and it has no major side effects even after prolonged use. The purpose of this study is to evaluate the effectiveness of bromelain and other nutraceuticals in reducing post-surgical swelling, pain and the need of anti-inflammatory drugs in maxillofacial post-traumatic surgery...
February 6, 2024: Journal of Clinical Medicine
#27
JOURNAL ARTICLE
Peter G Chiarelli, Bismarck Martinez, Takashi Nakamura, Kevin Mis Solval
Pineapple by-products are good sources of bromelain, a complex enzyme with commercial applications. This study evaluated the feasibility of producing bromelain powders from pineapple waste using an organic solvent-free approach. Pineapple by-products (from var. MD2), including cores, peels, crowns, stems, and basal stems, were homogenized with deionized water, and the pH of the mixture was adjusted to 4.5 and 9 (isoelectric points of fruit bromelain and stem bromelain), clarified, ultra-filtered, and freeze-dried to produce bromelain powders...
February 15, 2024: Foods (Basel, Switzerland)
#28
JOURNAL ARTICLE
Luigi Meccariello, Anna Iolanda Bello, Giovanni Bove, Nicola Gagliardo, D'Anna Raffaele, Luigi Matera
Aim To investigate whether the use of ion resonance and bromelain-vitamin C or bromelain-vitamin C is the best to prevent ankle complications in post operative bimalleolar surgery. Methods A total of 61 patients treated with bimalleolar surgery were enrolled. The patients were divided into three groups: the first group (n=22) treated only with the surgery, the second group (n=18) treated by ion resonance and bromelain-vitamin C, and the third group (n=21) was treated with bromelain-vitamin C. All patients in the second and third group underwent adjuvant therapy for 50 days...
February 1, 2024: Medicinski Glasnik
#29
JOURNAL ARTICLE
Ritika Kaushal, Brahmeet Kaur, Parmjit S Panesar, Anil K Anal, Son Chu-Ky
Huge amount of waste is generated by the pineapple processing industries which raises concerns regarding its safe disposal into the environment. This ever-increasing problem of waste management can be solved by the valorization of pineapple by-products to high-value compounds. The extraction of proteolytic enzyme, bromelain from pineapple rind using green techniques can help to overcome the drawbacks associated with conventional methods. In the present study, the extraction of bromelain from pineapple rind using microwave assisted technique resulted in considerable amount of proteolytic activity (127...
March 2024: Journal of Food Science and Technology
#30
REVIEW
Amlendu Shekhar, Nisha Maddheshiya, Adit, Varun Rastogi, Karthikeyan Ramalingam
The objective of this systematic review was to assess the effectiveness, acceptability, and safety of systemic enzyme therapy, consisting of trypsin, bromelain, and rutoside trihydrate, as an anti-inflammatory agent, either when utilized independently or in conjunction with non-steroidal anti-inflammatory drugs (NSAIDs). This systematic review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Two studies met the inclusion criteria and were assessed in the review...
January 2024: Curēus
#31
JOURNAL ARTICLE
Márjorie Castro Pinto Porfirio, Jonathan Barbosa Santos, Annie Nolasco Alves, Leandro Soares Santos, Renata Cristina Ferreira Bonomo, Rafael da Costa Ilhéu Fontan
This study investigated the purification of bromelain obtained from pineapple fruit using a new adsorbent for immobilized metal ion affinity chromatography (IMAC), with chlorophyll obtained from plant leaves as a chelating agent. The purification of bromelain was evaluated in batches from the crude extract of pineapple pulp (EXT), and the extract precipitated with 50 % ammonium sulfate (EXT.PR), the imidazole buffer (200 mM, pH 7.2) being analyzed and sodium acetate buffer, pH 5.0 + 1.0 NaCl as elution solutions...
January 22, 2024: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
#32
JOURNAL ARTICLE
Yaojun Ju, Dingdong Bu, Haozhe Wang, Bingye Li, Dai Cheng
Food derived bioactive peptides are prominent dietary supplements to protect against oxidative stress induced by lead (Pb) exposure. This study aimed to develop a new strategy for rapid preparation of highly active antioxidant soybean polypeptides (ASPs) against Pb toxicity. In silico enzymatic hydrolysis simulation and antioxidant activity prediction showed that pepsin, chymotrypsin and bromelain can produce peptides with the highest activity. The preparation process was then optimized, and the obtained ASP showed good antioxidant and metal-chelating activities in vitro ...
January 30, 2024: Food & Function
#33
JOURNAL ARTICLE
Robert J Snyder, Adam J Singer, Cyaandi R Dove, Stephen Heisler, Howard Petusevsky, Garth James, Elinor deLancey Pulcini, Aya Ben Yaakov, Lior Rosenberg, Edward Grant, Yaron Shoham
BACKGROUND: Most chronic wounds contain biofilm, and debridement remains the centerpiece of treatment. Enzymatic debridement is an effective tool in removing nonviable tissue, however, there is little evidence supporting its effect on planktonic and biofilm bacteria. OBJECTIVE: This study evaluated the effects of a novel BBD agent on removal of nonviable tissue, biofilm, and microbial loads in patients with chronic ulcers. MATERIALS AND METHODS: Twelve patients with DFU or VLU were treated with up to 8 once-daily applications of BBD and then followed for an additional 2 weeks...
December 2023: Wounds: a Compendium of Clinical Research and Practice
#34
JOURNAL ARTICLE
Xinyi Zhou, Jian Wang, Jingxu Zhao, Chunhong Yuan, Xiaojun Zhang, Tao Huang, Wenge Yang, Huamao Wei
BACKGROUND: In order to improve the tenderness of dried shrimp products as well as to reduce the hardness of the meat during the drying process, shrimp were treated with ultrasound combined with pineapple protease and the tenderization condition was optimized by measuring the texture and shear force of dried shrimp. In addition, the sulfhydryl content, myofibril fragmentation index (MFI) and microstructure were also examined to clarify the mechanisms of shrimp tenderization. RESULTS: The results showed UB1 group with ultrasonic power of 100 W, heating temperature of 50 °C and pineapple protease concentration of 20 U mL-1 were the optimum tenderization conditions, where shrimp showed the lowest hardness (490...
January 24, 2024: Journal of the Science of Food and Agriculture
#35
JOURNAL ARTICLE
Effect of the use of bromelain associated with bioactive glass-ceramic on dentin/adhesive interface.
Rocio Geng Vivanco, Ana Beatriz Silva Sousa, Viviane de de Cássia Oliveira, Mário Alexandre Coelho Sinhoreti, Fernanda de Carvalho Panzeri Pires-de-Souza
OBJECTIVES: To evaluate the effect of bromelain associated with Biosilicate on the bond strength (BS) of a universal adhesive system to sound (SD) and caries-affected dentin (CAD), and on the proteolytic activity. MATERIALS AND METHODS: Cavities were prepared in 360 molars, half submitted to cariogenic challenge. Teeth were separated into groups (n=20): Control-No treatment; CHX-0.12% chlorhexidine; NaOCl-5% sodium hypochlorite; Br5%-5% bromelain; Br10%-10% bromelain; Bio-10% Biosilicate; NaOClBio-NaOCl+Bio; Br5%Bio-Br5%+Bio; Br10%Bio-Br10%+Bio...
January 20, 2024: Clinical Oral Investigations
#36
JOURNAL ARTICLE
Yolandani, Dandan Liu, Fredy Agil Raynaldo, Mokhtar Dabbour, Xueli Zhang, Zhongyuan Chen, Qingzhi Ding, Lin Luo, Haile Ma
The bitterness of soy protein isolate hydrolysates prepared using five proteases at varying degree of hydrolysis (DH) and its relation to physicochemical properties, i.e., surface hydrophobicity (H0 ), relative hydrophobicity (RH), and molecular weight (MW), were studied and developed for predictive modelling using machine learning. Bitter scores were collected from sensory analysis and assigned as the target, while the physicochemical properties were assigned as the features. The modelling involved data pre-processing with local outlier factor; model development with support vector machine, linear regression, adaptive boosting, and K-nearest neighbors algorithms; and performance evaluation by 10-fold stratified cross-validation...
January 13, 2024: Food Chemistry
#37
JOURNAL ARTICLE
Ekaterina Potapova, Salvatore Tripodi, Valentina Panetta, Stephanie Dramburg, Roberto Bernardini, Carlo Caffarelli, Antonella Casani, Rosa Cervone, Loredana Chini, Pasquale Comberiati, Giovanna De Castro, Michele Miraglia Del Giudice, Iride Dello Iacono, Andrea Di Rienzo Businco, Marcella Gallucci, Arianna Giannetti, Viviana Moschese, Ifigenia Sfika, Elena Varin, Riccardo Asero, Annamaria Bianchi, Mauro Calvani, Tullio Frediani, Francesco Macrì, Nunzia Maiello, Francesco Paravati, Umberto Pelosi, Diego Peroni, Giuseppe Pingitore, Mariangela Tosca, Anna Maria Zicari, Giampaolo Ricci, Gerald Reese, Linus Grabenhenrich, Katja Icke, Armin Grübl, Christoph Müller, Fred Zepp, Antje Schuster, Ulrich Wahn, Susanne Lau, Thomas Keil, Paolo Maria Matricardi
BACKGROUND: IgE antibodies to cross-reactive carbohydrate determinants (CCD) are usually clinically irrelevant but they can be a cause of false positive outcomes of allergen-specific IgE tests in vitro. Their prevalence and levels have been so far cross-sectionally examined among adult allergic patients and much less is known about their origins and relevance in childhood. METHODS: We examined CCD with a cross-sectional approach in 1263 Italian pollen allergic children (Panallergen in Paediatrics, PAN-PED), as well as with a longitudinal approach in 612 German children (Multicenter Allergy Study, MAS), whose cutaneous and IgE sensitization profile to a broad panel of allergen extracts and molecules was already known...
January 17, 2024: Clinical and Experimental Allergy
#38
JOURNAL ARTICLE
Yihang Zhang, Jing Guo, Jianbin Sun, Fucheng Guan, Jing Tao, Xuecui Song, Zheng Li
Tea bags have been extensively used in the food industry and daily life as an efficient way to pack tea. However, the large pores of the commercial tea bags not only lead to the inner contents of tea bag susceptible to bacteria and moisture but also result in the faster water infusion which is undesired during tea brewing. In this study, the polylactic acid (PLA)-PLA/sodium alginate (SA)/bromelain (BL) bilayer fiber membrane imitating the asymmetric wetting structure of lotus leaf blades was fabricated to avoid the above disadvantages of commercial tea bag...
January 15, 2024: International Journal of Biological Macromolecules
#39
JOURNAL ARTICLE
Surjit Kaur, Todor Vasiljevic, Thom Huppertz
Plant proteases, including actinidin, papain and bromelain, have been widely used in the food industry but with limited application in dairy systems. This research aimed to establish and compare operational parameters (kinetics, temperature, enzyme type, time and thermodynamics) relevant to the applications of these enzymes in the hydrolysis of whey protein isolates (WPI), whey protein concentrates (WPC) or milk protein concentrates (MPC). The degree of hydrolysis (DH) increased with the rise in temperature, and the maximum DH was achieved at 60 °C for all three dairy systems...
November 24, 2023: Foods (Basel, Switzerland)
#40
JOURNAL ARTICLE
Iwona Szerszunowicz, Szymon Kozicki
The immune response of humans may be modulated by certain biopeptides. The present study aimed to determine the immunomodulatory potential of plant-derived food proteins and hydrolysates obtained from these proteins via monocatalytic in silico hydrolysis (using ficin, stem bromelainm or pepsin (pH > 2)). The scope of this study included determinations of the profiles of select bioactivities of proteins before and after hydrolysis and computations of the frequency of occurrence of selected bioactive fragments in proteins (parameter A), frequency/relative frequency of the release of biopeptides (parameters AE , W) and the theoretical degree of hydrolysis (DHt ), by means of the resources and programs available in the BIOPEP-UWM database...
December 29, 2023: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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