Leôncio L Soares, Luciano B Leite, Maíra O Freitas, Luiz Otávio G Ervilha, Mayra S Píccolo, Alexandre M O Portes, Filipe R Drummond, Leonardo Mateus T DE Rezende, Mariana M Neves, Emily C C Reis, Miguel A Carneiro-Júnior, Antônio José Natali
Pulmonary arterial hypertension (PAH) is characterized by right ventricular failure and diminished cardiac output, potentially leading to renal and bone impairments. In contrast, resistance exercise training (RT) offers cardiovascular and bone health benefits. This study aimed to assess the impacts of stable PAH induced by monocrotaline (MCT) and RT on renal morphometry, as well as bone morphometry and biomechanical properties in male Wistar rats. Four experimental groups, untrained control (UC, n=7), trained control (TC, n=7), untrained hypertensive (UH, n=7), trained hypertensive (TH, n=7), were defined...
2024: Anais da Academia Brasileira de Ciências