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https://www.readbyqxmd.com/read/29453756/acute-effects-of-unilateral-static-stretching-on-handgrip-strength-of-the-stretched-and-non-stretched-limb
#1
Jacob D Jelmini, Andrew Cornwell, Nazareth Khodiguian, Jennifer Thayer, And John Araujo
PURPOSE: To determine the effects of an acute bout of unilateral static stretching on handgrip strength of both the stretched and non-stretched limb. It was reasoned that if the non-stretched limb experienced a decrease in force output, further evidence for a neural mechanism to explain a post-stretch force reduction would be obtained as no mechanical adaptation would have occurred. METHODS: Thirty participants performed maximum voluntary unilateral handgrip contractions of both limbs before and after stretching the finger flexors of the strength-dominant side only...
February 16, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29453752/satisfied-patients-after-shoulder-arthrodesis-for-brachial-plexus-lesions-even-after-20-years-of-follow-up
#2
M A J van der Lingen, S G C J de Joode, M G M Schotanus, B Grimm, F A van Nie, L A W M Speth, S K Samijo
PURPOSE: Patients with an upper brachial plexus lesion can suffer from dysfunction, joint deformities and instability of the shoulder. The goal of this study was to determine pain, shoulder function, patient satisfaction and muscle strength in shoulder arthrodesis in patients with an upper brachial plexus lesion more than 15 years after surgery. METHODS: We retrospectively studied 12 patients with a brachial plexus lesion of mean age 46 years (27-61). At a mean of 19...
February 16, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29452288/repetitive-tlr-3-activation-in-the-lung-induces-skeletal-muscle-adaptations-and-cachexia
#3
Ted G Graber, Brandy L Rawls, Bing Tian, William J Durham, Camille R Brightwell, Allan R Brasier, Blake B Rasmussen, Christopher S Fry
Due to immunosenescence, older adults are particularly susceptible to lung-based viral infections, with increased severity of symptoms in those with underlying chronic lung disease. Repeated respiratory viral infections produce lung maladaptations, accelerating pulmonary dysfunction. Toll like 3 receptor (TLR3) is a membrane protein that senses exogenous double-stranded RNA to activate the innate immune response to a viral infection. Polyinosinic-polycytidylic acid [poly(I:C)] mimics double stranded RNA and has been shown to activate TLR3...
February 13, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29451497/automated-skeletal-tissue-quantification-in-the-lower-leg-using-pqct
#4
Sokratis Makrogiannis, Fatima Boukari, Luigi Ferrucci
In this paper we introduce a methodology for hard and soft tissue quantification at proximal, intermediate and distal tibia sites using peripheral Quantitative Computed Tomography (pQCT) scans. Quantification of bone properties is crucial for estimating bone structure resistance to mechanical stress and adaptations to loading. Soft tissue variables can be computed to investigate muscle volume and density, muscle-bone relationship, and fat infiltration.
 Approach: We employed implicit active contour models and clustering techniques for automated segmentation and identification of bone, muscle and fat at 4%, 38%, and 66% tibia length...
February 15, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29450728/winter-vitamin-d-3-supplementation-does-not-increase-muscle-strength-but-modulates-the-igf-axis-in-young-children
#5
Charlotte Mortensen, Christian Mølgaard, Hanne Hauger, Michael Kristensen, Camilla T Damsgaard
PURPOSE: To explore whether muscle strength, the insulin-like growth factor axis (IGF-axis), height, and body composition were associated with serum 25-hydroxyvitamin D [25(OH)D] and affected by winter vitamin D supplementation in healthy children, and furthermore to explore potential sex differences. METHODS: We performed a double-blind, placebo-controlled, dose-response winter trial at 55ºN. A total of 117 children aged 4-8 years were randomly assigned to either placebo, 10, or 20 µg/day of vitamin D 3 for 20 weeks...
February 15, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29449193/phase-i-trial-of-intrathecal-mesenchymal-stem-cell-derived-neural-progenitors-in-progressive-multiple-sclerosis
#6
Violaine K Harris, James Stark, Tamara Vyshkina, Leslie Blackshear, Gloria Joo, Valentina Stefanova, Gabriel Sara, Saud A Sadiq
BACKGROUND: Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system and is one of the leading causes of disability in young adults. Cell therapy is emerging as a therapeutic strategy to promote repair and regeneration in patients with disability associated with progressive MS. METHODS: We conducted a phase I open-label clinical trial investigating the safety and tolerability of autologous bone marrow mesenchymal stem cell-derived neural progenitor (MSC-NP) treatment in 20 patients with progressive MS...
February 3, 2018: EBioMedicine
https://www.readbyqxmd.com/read/29447959/effects-of-maturation-and-advanced-glycation-on-tensile-mechanics-of-collagen-fibrils-from-rat-tail-and-achilles-tendons
#7
Rene B Svensson, Stuart T Smith, Patrick J Moyer, S Peter Magnusson
Connective tissues are ubiquitous throughout the body and consequently affect the function of many organs. In load bearing connective tissues like tendon, the mechanical functionality is provided almost exclusively by collagen fibrils that in turn are stabilized by covalent cross-links. Functionally distinct tendons display different cross-link patterns, which also change with maturation, but these differences have not been studied in detail at the fibril level. In the present study, a custom built nanomechanical test platform was designed and fabricated to measure tensile mechanics of individual fibrils from rat tendons...
February 12, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29447092/evolution-of-muscular-fatigue-in-periscapular-and-rotator-cuff-muscles-during-isokinetic-shoulder-rotations
#8
Sylvain Gaudet, Jonathan Tremblay, Fabien Dal Maso
To this day, how shoulder muscles react to a strong fatigue stimulus during dynamic shoulder rotations remains unknown. The aims of this study were to assess the effect of repeated maximal internal-external isokinetic shoulder rotations on shoulder strength and muscle activity. Twenty-four individuals completed a 50-repetition fatiguing isokinetic protocol while electromyography was recorded on eleven muscles of the shoulder girdle. Time-frequency transformation and an ANOVA model using statistical parametric mapping methods were used to analyze shifts in instantaneous median frequency (MDF) between each 10-repetition Blocks...
February 15, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29446711/neurophysiological-adaptations-in-the-untrained-side-in-conjunction-with-cross-education-of-muscle-strength-a-systematic-review-and-meta-analysis
#9
Andrea Manca, Tibor Hortobagyi, John C Rothwell, Franca Deriu
We reviewed the evidence from randomized controlled trials (RCTs) focusing on the neurophysiological adaptations in the untrained side associated with cross-education of strength (CE) and pooled data into definite effect estimates for neurophysiological variables assessed in chronic CE studies. Furthermore, scoping directions for future research were provided to enhance the homogeneity and comparability of studies investigating the neural responses to CE. The magnitude of CE was 21.1{plus minus}18.2% (p<0...
February 15, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29446524/impact-of-blood-flow-restricted-bodyweight-exercise-on-skeletal-muscle-adaptations
#10
J E Jakobsgaard, M Christiansen, P Sieljacks, J Wang, T Groennebaek, F de Paoli, K Vissing
This study ascertains the ability of bodyweight blood flow-restricted (BFR) exercise training to promote skeletal muscle adaptations of significance for muscle accretion and metabolism. Six healthy young individuals (three males and three females) performed six weeks of bodyweight BFR training. Each session consisted of five sets of sit-to-stand BFR exercise to volitional failure with 30-second inter-set recovery. Prior to, and at least 72 h after training, muscle biopsies were taken from m. vastus lateralis to assess changes in fibre type-specific cross-sectional area (CSA), satellite cell (SC) and myonuclei content and capillarization, as well as mitochondrial protein expression...
February 15, 2018: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29446121/atrophy-of-hip-abductor-muscles-is-related-to-clinical-severity-in-a-hip-osteoarthritis-population
#11
Anita Zacharias, Rodney A Green, Adam Semciw, Daniel J English, Theo Kapakoulakis, Tania Pizzari
INTRODUCTION: Osteoarthritis mainly affects weight-bearing joints such as the hip and knee and is the most common form of arthritis. Greater muscle atrophy with fatty infiltration of gluteal muscles and decreased hip abduction strength has previously been identified with increasing severity of radiological hip OA. However, it is well documented that radiographic findings of OA do not always correlate with clinical severity. The aim of this secondary analysis was to examine whether atrophy and strength of gluteus maximus (GMax), medius (GMed), minimus (GMin), and tensor fascia lata (TFL) is associated with the clinical severity of OA...
February 15, 2018: Clinical Anatomy
https://www.readbyqxmd.com/read/29445830/bone-health-assessment-in-older-people-with-or-without-muscle-health-impairment
#12
M Locquet, C Beaudart, O Bruyère, J A Kanis, L Delandsheere, J-Y Reginster
This study investigated the relationship between muscle and bone status in elderly individuals. Our results suggested links between sarcopenia and osteoporosis; impairment in muscle status (i.e., muscle mass, muscle strength, and physical performance) is associated with deterioration in bone mass and texture subsequently leading to an increased risk of fracture. INTRODUCTION: Accumulating evidence has shown associations between sarcopenia and osteoporosis, but existing studies face inconsistencies in the clinical definition of both conditions...
February 14, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29445330/non-neural-muscle-weakness-has-limited-influence-on-complexity-of-motor-control-during-gait
#13
Marije Goudriaan, Benjamin R Shuman, Katherine M Steele, Marleen Van den Hauwe, Nathalie Goemans, Guy Molenaers, Kaat Desloovere
Cerebral palsy (CP) and Duchenne muscular dystrophy (DMD) are neuromuscular disorders characterized by muscle weakness. Weakness in CP has neural and non-neural components, whereas in DMD, weakness can be considered as a predominantly non-neural problem. Despite the different underlying causes, weakness is a constraint for the central nervous system when controlling gait. CP demonstrates decreased complexity of motor control during gait from muscle synergy analysis, which is reflected by a higher total variance accounted for by one synergy (tVAF 1 )...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29444538/-effects-of-judo-specific-resistance-training-on-kinetic-and-electromyographic-parameters-of-pulling-exercises-in-judo-athletes
#14
Norman Helm, Olaf Prieske, Thomas Muehlbauer, Tom Krüger, Urs Granacher
BACKGROUND: In judo, rapid force production during pulling movements is an important component of athletic performance, which is why this capacity needs to be specifically exercised in judo. This study aimed at examining the effects of a judo-specific resistance training program using a judo ergometer system (PTJ) versus a traditional resistance training regime using a partner (PTP) on kinetics and muscle activity of judo-specific pulling exercises. METHOD: Twenty-four male judo athletes (age: 22 ± 4 years, training experience: 15 ± 3 years) were randomly assigned to two groups...
February 14, 2018: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/29443415/comprehensive-assessment-of-the-donor-site-of-the-anterolateral-thigh-flap-a-prospective-study-in-33-patients
#15
Shuang Bai, Zhi-Qiang Zhang, Zhi-Qiang Wang, Zhong-Fei Xu, Wei-Yi Duan, Fa-Yu Liu, Xue-Xin Tan, Chang-Fu Sun
BACKGROUND: The anterolateral thigh (ALT) free flap has been an extremely versatile flap. The purpose of this study was to propose comprehensive functional assessments of the donor site. METHODS: A total of 33 ALT flaps were enrolled prospectively. Objective assessments included isokinetic testing of the knee, and electromyographic examination of the lateral femoral cutaneous nerve (LFCN). The Patient and Observer Scar Assessment Scale (POSAS) was used to subjectively assess the donor-site scar...
February 14, 2018: Head & Neck
https://www.readbyqxmd.com/read/29443059/in-vivo-electrophysiological-measurement-of-the-rat-ulnar-nerve-with-axonal-excitability-testing
#16
Brandon M Wild, Renée Morris, Mihai Moldovan, Christian Krarup, Arun V Krishnan, Ria Arnold
Electrophysiology enables the objective assessment of peripheral nerve function in vivo. Traditional nerve conduction measures such as amplitude and latency detect chronic axon loss and demyelination, respectively. Axonal excitability techniques "by threshold tracking" expand upon these measures by providing information regarding the activity of ion channels, pumps and exchangers that relate to acute function and may precede degenerative events. As such, the use of axonal excitability in animal models of neurological disorders may provide a useful in vivo measure to assess novel therapeutic interventions...
February 6, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29442538/serum-cystatin-c-level-is-associated-with-locomotive-syndrome-risk-and-can-be-an-early-predictor-in-community-living-people-the-yakumo-study
#17
Satoshi Tanaka, Kei Ando, Kazuyoshi Kobayashi, Tetsuro Hida, Kenyu Ito, Mikito Tsushima, Masayoshi Morozumi, Masaaki Machino, Kyotaro Ota, Taisuke Seki, Koji Suzuki, Yoshihiro Nishida, Naoki Ishiguro, Yukiharu Hasegawa, Shiro Imagama
OBJECTIVES: The locomotive syndrome (LS) risk has been recently proposed as a criterion for evaluating physical ability. Serum cystatin C level is an early renal function marker and a cardiovascular disease predictor. This study aimed to evaluate the relationship between serum cystatin C level and LS risk. METHODS: We enrolled 54 participants and conducted the two-step test, stand-up test, 25-question geriatric locomotive function scale, LS risk test, Timed Up and Go test, back muscle strength, grip strength, blood test, and serum cystatin C level measurement...
February 14, 2018: Modern Rheumatology
https://www.readbyqxmd.com/read/29439674/establishing-a-clinical-phenotype-for-cachexia-in-end-stage-kidney-disease-study-protocol
#18
Joanne Reid, Helen R Noble, Gary Adamson, Andrew Davenport, Ken Farrington, Denis Fouque, Kamyar Kalantar-Zadeh, John Mallett, C McKeaveney, S Porter, David S Seres, Joanne Shields, Adrian Slee, Miles D Witham, Alexander P Maxwell
BACKGROUND: Surveys using traditional measures of nutritional status indicate that muscle wasting is common among persons with end-stage kidney disease (ESKD). Up to 75% of adults undergoing maintenance dialysis show some evidence of muscle wasting. ESKD is associated with an increase in inflammatory cytokines and can result in cachexia, with the loss of muscle and fat stores. At present, only limited data are available on the classification of wasting experienced by persons with ESKD...
February 13, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29439373/factors-associated-with-high-physical-exertion-during-manual-lifting-cross-sectional-study-among-200-blue-collar-workers
#19
Lars L Andersen, Emil Sundstrup, Mikkel Brandt, Efat Lali Dastjerdi, Roger Persson, Markus D Jakobsen
BACKGROUND: High physical exertion during work is a risk factor for back pain and long-term sickness absence. OBJECTIVE: To investigate which factors are associated with physical exertion during manual lifting. METHODS: From 14 workplaces across Denmark, 200 blue-collar workers reported perceived physical exertion (Borg-CR10) during manual lifting from floor to table height of 5, 10, 20 and 30 kg at the beginning and end of the working day...
2018: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/29439362/effects-of-transcranial-direct-current-stimulation-on-walking-ability-after-stroke-a-systematic-review-and-meta-analysis
#20
Yi Li, Jingjing Fan, Jingyi Yang, Chengqi He, Shasha Li
BACKGROUND: As a promising technique, transcranial direct current stimulation (tDCS) has gained so much attention in its potential effects on functional recovery of lower limb following stroke. However, individual studies have yielded inconsistent or conflicting results. OBJECTIVE: To investigate the efficacy and safety of tDCS for the functional recovery of lower limb following stroke reported in the randomized controlled trials by using a meta-analysis. METHODS: MEDLINE, EMBASE, CINAHL, PsycINFO, Web of Science, CENTRAL, and Physiotherapy Evidence Database was comprehensively searched for randomized controlled trials published until April 2017 that investigated the effects of tDCS on lower limb function...
2018: Restorative Neurology and Neuroscience
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