keyword
https://read.qxmd.com/read/38546927/a-rare-clinical-case-of-systemic-aa-amyloidosis-with-cardiac-involvement-complicating-ankylosing-spondylitis-a-case-report
#1
JOURNAL ARTICLE
Leïla Barakat, Khadija Echchilali, Mina Moudatir, Hassan El Kabli, Yassine Ettagmouti, Mériem Haboub, Salim Arous, Mohamed Ghali Benouna, Abdenasser Drighil, Rachida Habbal, Meryame Azim, Asmae Mazti, Meriem Regragui, Nissrine Bennani Guebessi, Mehdi Karkouri
BACKGROUND: Ankylosing spondylitis (AS) is a type of chronic inflammation that is most prevalent in young adults and is characterized by an inflammatory enthesiopathy that gradually develops toward ossification and ankylosis. If inflammation is left unchecked, it can potentially lead to complications such as secondary amyloidosis, also known as AA amyloidosis, involving the deposition of amyloid serum A protein. Our case presents with a thyroid localization of AA amyloidosis which is secondary to this AS...
March 28, 2024: Egyptian Heart Journal: EHJ
https://read.qxmd.com/read/38544658/sensitivity-and-specificity-analysis-of-fine-needle-aspiration-cytology-fnac-for-thyroid-swelling
#2
JOURNAL ARTICLE
Mangesh G Kohale, Anupama V Dhobale, Nandkishor J Bankar, Neha Bhatt, Akshay H Salgar
Introduction Thyroid gland disorders, such as goiters or tumor masses, are the result of localized or systemic aberrations of the thyroid gland. The purpose of this research was to see how effective fine needle aspiration cytology (FNAC) was in detecting thyroid swelling in patients with thyroid swelling. It is critical to be able to differentiate between benign and malignant thyroid nodules to reduce unnecessary thyroid surgeries. It is hypothesized that FNAC is not a reliable diagnostic tool to detect thyroid nodules in patients with thyroid swelling and that there is a significant variation between the number of thyroid nodules detected by FNAC and the number of thyroid nodules that were eventually diagnosed as malignant by surgery...
February 2024: Curēus
https://read.qxmd.com/read/38544612/forgotten-goiter-presenting-as-acute-respiratory-distress-following-a-thyroidectomy-a-case-report
#3
Beatriz Marques, Rita Oliveira, Roberto J Ameiro, Manuela Paiva
Airway complications account for a significant amount of post-thyroidectomy complications. Forgotten goiter is a residual thyroid mass left after total thyroidectomy, an event already depicted in the literature. Clinical presentation is diverse, ranging from asymptomatic tracheal deviation to symptoms caused by hormonally active thyroid tissue or airway obstruction due to mass effect. However, it has never been documented as the cause of acute respiratory distress following thyroid surgery. We report the case of a 65-year-old female undergoing left hemithyroidectomy due to long-standing substernal goiter...
February 2024: Curēus
https://read.qxmd.com/read/38544601/high-malignancy-risk-and-its-predictors-in-south-indian-patients-with-bethesda-ii-thyroid-nodules
#4
JOURNAL ARTICLE
Sunanda Tirupati, Pradeep Puthenveetil, Shilpa Lakkundi, Anudeep Gaddam, Vijaya Sarathi
BACKGROUND: Global data reports a low malignancy risk, whereas regional data report a variable risk of malignancy in Bethesda II thyroid nodules. The limited availability of surgical histopathology might have underestimated the risk of malignancy. Here, we report the prevalence of malignancy and its predictors in Bethesda II thyroid nodules for which the surgical histopathological diagnosis was available. METHODS:  This retrospective study was done at a tertiary healthcare center in South India between January 2008 and September 2015...
February 2024: Curēus
https://read.qxmd.com/read/38537502/nkx2-1-gene-is-targeted-by-h19-lncrna-and-is-found-to-be-overexpressed-in-benign-nodular-goiter-tissues
#5
JOURNAL ARTICLE
Seyed-Morteza Javadirad
OBJECTIVE: Nodular goiter may increase the risk of thyroid cancer, but the genetic factors contributing to nodular goiter are not well understood. There is an overexpression of H19 lncRNA in goiter tissue and its target remains unknown. In this study, we attempted to identify a new target for H19 in the context of goiter development. METHODS: Using interaction energy calculations, the interaction between NKX2-1 mRNA and H19 lncRNA was examined. Putative microRNAs were found at the H19 lncRNA target site with the highest affinity for NKX2-1...
February 28, 2024: Brazilian Journal of Otorhinolaryngology
https://read.qxmd.com/read/38532265/clinical-and-magnetic-resonance-imaging-findings-in-a-french-bulldog-puppy-with-genetically-confirmed-congenital-hypothyroidism
#6
Katia Sánchez González, Harry Warwick, Marius Conradie, Neringa Alisauskaite
A 7-month-old male French bulldog was referred for abnormal mentation and gait. Physical examination revealed a dome shaped calvarium and persistent bregmatic fontanelle. Neurological examination revealed proprioceptive ataxia, pelvic limb paraparesis and strabismus with moderate ventriculomegaly, thinning of the cerebral parenchyma, and widened cerebral sulci on magnetic resonance imaging. Masses were identified in the region of the thyroid, which appeared heterogeneous and hyperintense in T1-weighted and T2-weighted compared with the adjacent muscle signal masses were identified...
March 26, 2024: Journal of Veterinary Internal Medicine
https://read.qxmd.com/read/38529708/the-effects-of-nebulized-lidocaine-on-the-laryngeal-adductor-reflex
#7
M Ángeles Sánchez Roldán, Héctor Duque, Bernat Masso, Dulce Moncho, Ramón Vilallonga, Manuel Armengol, Óscar González
The laryngeal adductor reflex (LAR) is a brainstem reflex that closes the vocal fold and constitutes a new method for continuously monitoring the vagus and laryngeal nerves during different surgeries. Previous reports concluded that topical lidocaine in spray inhibited LAR responses. However, topical anesthesia in the upper airway may be necessary in awake intubation. We present six patients who underwent neck endocrine surgery due to an intrathoracic goiter that compromised the airway. Before awake intubation, a nebulization of lidocaine 5% was applied for at least 10 min...
March 26, 2024: Laryngoscope
https://read.qxmd.com/read/38524065/thyroidectomy-effects-on-the-body-mass-index-and-thyroid-stimulating-hormone-a-systematic-review-and-meta-analysis
#8
REVIEW
Hyder Mirghani, Ahmad M Fnjan, Abdullah F Almalki, Ali F Almadan, Omar Abdullah M Alammar, Abdulaziz S Alhwiati, Amer A Laradhi, Ahmed M Bakour, Mohamad A Aljahed, Abdulmajeed M Alzahrani
Thyroidectomy is common and is performed for malignancy, goiters with pressure symptoms, and certain types of Grave's disease. Weight and body mass index (BMI) following thyroidectomy were discussed controversially. This meta-analysis aimed to assess weight and BMI following thyroidectomy. A systematic literature search was conducted in PubMed, Medline, and Google Scholar with interest in articles that assessed body weight and BMI following total or subtotal thyroidectomy. The search engine was limited to the period from inception up to January 2024...
February 2024: Curēus
https://read.qxmd.com/read/38523848/a-rare-case-of-persistent-multifocal-cribriform-morular-thyroid-carcinoma
#9
William Kuenstner, Po Zhao, Wen Lee, Carlos Garcia, Kenneth D Burman, Leila Shobab
BACKGROUND/OBJECTIVE: Cribriform-morular thyroid carcinoma (CMTC) was considered a variant of papillary thyroid carcinoma (PTC) but is a separate entity in the 2022 World Health Organization classification. CMTC has an association with familial adenomatous polyposis (FAP). Our objective is to report a case of CMTC who was subsequently diagnosed with FAP, to highlight these associated entities and implications for management. CASE REPORT: A 15-year-old female with a history of iron-deficiency anemia and alpha-gal syndrome presented with several years of goiter and dysphagia...
2024: AACE Clinical Case Reports
https://read.qxmd.com/read/38523345/assessment-of-thyroid-gland-in-children-with-point-of-care-ultrasound-pocus-radiological-performance-and-feasibility-of-handheld-ultrasound-in-clinical-practice
#10
JOURNAL ARTICLE
Ahmet Anık, Mustafa Gök, Göksel Tuzcu
BACKGROUND: Point-of-Care Ultrasound (POCUS) refers to the use of portable ultrasound machines to perform quick and focused ultrasound examinations at a patient's bedside or point-of-care. POCUS can be performed by all health workers with specific training to use POCUS. This study aimed to investigate the radiological performance and feasibility of POCUS using a handheld ultrasound (HHUSD) system in children from the perspective of the thyroid gland perspective. MATERIAL-METHODS: A pediatric endocrinologist performed thyroid imaging in children referred to our hospital with suspected thyroid disease using an HHUSD system...
March 25, 2024: Journal of Clinical Research in Pediatric Endocrinology
https://read.qxmd.com/read/38518471/a-case-report-of-coexisting-multinodular-goiter-with-carotid-body-tumor
#11
Ahmad Fawad Wardak, Torgot Ghani, Sayed Ismatullah Ardam, Munir Ahmad Musamim, Turan Ghani, Haroon Alamy
INTRODUCTION: Carotid body tumor (CBT), a neuroendocrine neoplasm, and benign multinodular goiter (BMNG) are distinct pathologies affecting the neck region. Although rare, they can occur concurrently. This case contributes to the limited evidence regarding the association between these distinct pathologies and their operative management. CASE PRESENTATION: The patient was a 45-year-old female with a palpable mass on the right side of her neck. She was diagnosed with Shamblin type III non-secretory CBT alongside BMNG...
March 20, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38516681/association-between-different-regional-lymph-node-metastases-of-papillary-thyroid-carcinoma-in-adolescents-and-young-adults
#12
JOURNAL ARTICLE
Lili Wang, Yahua Zheng, Yingpeng Ye, Zhekang Jiang, Jinling Lu, Gaoxiang Chen
Adolescents and young adults (AYA) describe the demographic aged between 15-39 years diagnosed with cancer. This group is particularly at risk of papillary thyroid carcinoma (PTC) with a greater severity compared with other ages. Through comparative design, the present study aimed to quantify central lymph node metastasis (CLNM) risk in AYAs. A total of 463 AYA patients with PTC and 489 patients >39 years old with PTC from Ningbo Medical Center Lihuili Hospital (Ningbo, China) were enrolled. Details such as demographic data, serum indices and fine-needle aspiration from the Electronic Medical Records System were extracted and analyzed...
May 2024: Oncology Letters
https://read.qxmd.com/read/38515523/does-consumption-of-pearl-millet-cause-goiter-a-systematic-review-of-existing-evidence
#13
Seetha Anitha, Shweta Upadhyay, Stefania Grando, Joanna Kane-Potaka
Millets (defined here to also include sorghum) have been consumed in Asian and African countries for centuries, and have in recent years become increasingly popular in Western countries, especially because of their proven health and environmental benefits. Nevertheless, some concerns have been raised that their consumption can interfere with thyroid function and cause goiter. This systematic review aimed to investigate the link between millet consumption and goiter. We found nine papers that were relevant to this topic and included them in this review...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38513357/female-rats-present-higher-oxidative-damage-and-inflammation-during-goitrogenesis
#14
JOURNAL ARTICLE
Caroline C Faria, Leonardo Matta Pereira, Luiz Gabriel Portilho Moreira, Kathelinie Celestino Faustino, Milena Simões Peixoto, Ariclécio Cunha de Oliveira, Andrea Claudia Freitas Ferreira, Denise Pires Carvalho, Rodrigo Soares Fortunato
Thyroid disorders affect more women than men, but the underlying mechanisms contributing to this disparity remain incompletely understood. Thyrotropin (TSH), the primary regulator of thyroid oxidative hormonogenesis, has been implicated as a risk factor for proliferative thyroid diseases and a predictor of malignancy. In this study, we aimed to evaluate the impact of sustained elevated TSH levels on thyroid redox homeostasis, inflammatory markers, and DNA damage response in both male and female rats. Rats were treated with methimazole for 7 or 21 days, and hormonal measurements were conducted...
March 1, 2024: Journal of Endocrinology
https://read.qxmd.com/read/38493559/benign-thyroid-nodules-classified-as-acr-ti-rads-4-or-5-imaging-and-histological-features
#15
JOURNAL ARTICLE
Jiamin Chen, Dalin Ye, Shuhui Lv, Xuefeng Li, Feile Ye, Yongquan Huang, Zhongzhen Su, Yuhong Lin, Ting Xie, Xin Wen
BACKGROUND: American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) being most widely applied in clinical practice, there is an overlap in US imaging manifestations between benign and malignant thyroid nodules. OBJECTIVES: To analyze the imaging and histological characteristics of pathological benign thyroid nodules categorized as American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) 4 or 5, and to explore the correlation between the suspicious sonographic signs resulting in the misdiagnoses and the histopathological features...
December 14, 2023: European Journal of Radiology
https://read.qxmd.com/read/38490098/uncommon-diagnosis-of-multinodular-goiter-isolated-extrapulmonary-manifestation-of-sarcoidosis-in-thyroid-gland-scientific-case-reports
#16
Marcel Neumann, Frank Meyer, Tatiana Oksentyuk Polyakova, Udo Barth, Dörthe Jechorek, Roland S Croner, Manuela Petersen
AIM: By means of the scientific description of two uncommon cases who underwent. surgical resection of multinodous goiter and following histopathological investigation revealing isolated extrapulmonary manifestation of sarcoidosis, this uncommon diagnosis including symptomatology, clinical findings, diagnostic and therapeutic management is to be illustrated. CASE DESCRIPTIONS: Diagnostics: Scintigraphy of the thyroid gland with a left-thyroid cold node; ultrasound-guided puncture (cytological investigation, non-suspicious)...
March 8, 2024: Pathology, Research and Practice
https://read.qxmd.com/read/38481116/a-rare-case-of-anatomical-variation-of-inferior-thyroid-artery-originated-from-the-brachiocephalic-trunk-during-retrosternal-goiter-excision
#17
JOURNAL ARTICLE
Lei Yang, Xiao Hu, Jinxian Luo
Vascular variations are prevalent among the human population. However, the occurrence of anatomical variations in the inferior thyroid artery originating directly from the brachiocephalic trunk (BCT) is exceptionally rare, as confirmed by numerous research studies. In addition, reliable departmental statistics reveal that the incidence rate of retrosternal goiter is approximately 19%. In this case study, the variation blood vessels in the neck were accidentally found and analyzed. Simultaneously, we conducted an analysis on the clinical significance of a rare anatomical variation...
March 13, 2024: Ear, Nose, & Throat Journal
https://read.qxmd.com/read/38473048/seasonal-diet-composition-of-goitered-gazelle-gazella-subgutturosa-in-an-arid-and-semi-arid-region-of-western-china
#18
JOURNAL ARTICLE
Nan Zhang, Zhirong Zhang, Chao Liu, Zeqin Xiong, Yaoyun Wei, Dehuai Meng, Meiling Zhan, Zongzhi Li, Yao Zhao, Liwei Teng, Zhensheng Liu
Global climate change, habitat fragmentation, and human interference have resulted in a significant, ongoing decline in the population of goitered gazelles. Effective conservation strategies require an understanding of resource requirements of threatened species, such as dietary needs. Therefore, we aimed to elucidate the food composition and seasonal dietary changes of goitered gazelles through microhistological analyses of fresh feces. Fabaceae (11.5%), Gramineae (9.4%), Chenopodiaceae (20.2%), Asteraceae (10...
February 20, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38470338/evaluation-of-the-prevalence-and-laboratory-test-results-of-overt-thyrotoxicosis-cases
#19
JOURNAL ARTICLE
Rabia Ezber, Ebru Demir Ülgen, İhsan Ateş, Nisbet Yilmaz
BACKGROUND: The frequency of thyrotoxicosis may vary between countries and some laboratory test results may be used in etiology research. This study aimed to evaluate the prevalence of thyrotoxicosis diagnoses and laboratory test results. METHODS: 3246 patients with overt thyrotoxicosis were included in this study. Laboratory test results, epicrisis, thyroid ultrasonography, thyroid scintigraphy, and radioactive iodine uptake test reports of the patients were examined in the study...
March 12, 2024: Romanian Journal of Internal Medicine
https://read.qxmd.com/read/38469981/subcutaneous-implantation-of-nodular-goiter-after-transoral-endoscopic-thyroidectomy-vestibular-approach-a-case-study-and-review-of-literature
#20
Yu-Jing Weng, Kristine J S Kwan, De-Biao Chen, Ben-Ling Hu, Jiang Jiang, Lei Min, Qing Ai, Wei-Chun Chen, Zhi-Heng Huang
BACKGROUND: Extrathyroid implantation or dissemination of thyroid tissue secondary to a thyroid procedure is rare. Most of these belonged to thyroid carcinoma with metastatic potential and uncommon for benign pathologies. METHODS: We report the case of a 31-year-old female who was identified to have multiple subcutaneous implantation of thyroid tissue 5 years after transoral endoscopic thyroidectomy vestibular approach. A comprehensive literature search on implantation of thyroid tissue secondary to thyroid procedures was performed...
March 12, 2024: Head & Neck
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