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https://www.readbyqxmd.com/read/29650436/iodine-nutrition-status-and-prevalence-of-abnormal-tsh-levels-in-schoolchildren-aged-6-7-years-in-the-autonomous-community-of-the-basque-country
#1
Juan José Arrizabalaga, Mercedes Jalón, Mercedes Espada, Mercedes Cañas, José María Arena, Lluís Vila
INTRODUCTION: An epidemiological study conducted between 1988 and 1992 showed iodine deficiency and endemic goiter in the schoolchildren of the autonomous community of the Basque Country. OBJECTIVES: 1) To ascertain the iodine nutrition status of schoolchildren aged 6-7 years, and 2) to estimate the prevalence of abnormal TSH levels in capillary blood. POPULATION AND METHODS: The study was conducted on 497 schoolchildren selected by random sampling...
April 10, 2018: Endocrinología, Diabetes y Nutrición
https://www.readbyqxmd.com/read/29622368/substernal-goiter-presenting-as-acute-respiratory-failure
#2
R Sousa Almeida, J Matos Costa
No abstract text is available yet for this article.
April 2, 2018: Revista Clínica Española
https://www.readbyqxmd.com/read/29619937/the-impact-of-surgery-on-quality-of-life-esophageal-motility-and-tracheal-anatomy-and-airflow-in-patients-with-benign-nodular-goiter
#3
Jesper Roed Sorensen
Surgery - is it any good for goiter? In patients with goiter the benefits of thyroid surgery have previously rarely been investigated, as only few alternatives existed. However, the increasing evidence of the advantages with non-surgical substitutes with lower costs and preferable risk profiles prompted us to investi-gate the evidence base for thyroid surgery thoroughly. This thesis consists of three published studies investigating the impact of thyroidectomy on: 1) changes in disease-specific quality of life, 2) swallowing symptoms and esophageal motility, and 3) tracheal anatomy and airflow, in a cohort of patients with benign nodular goiter...
April 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29600295/a-78-year-old-man-with-historical-goiter
#4
Amel Ait Boudaoud, Claire Rives-Lange, Alina Radu, François Rubin, Claire Carette, Charles Barsamian, Sebastien Czernichow
The purpose of this paper is to provide description of the natural evolution of an initially operable goitre into unmesurable form in a context of deeply unknown psychiatric disorders initially unknown.
March 1, 2018: Journal of the Endocrine Society
https://www.readbyqxmd.com/read/29599647/prognostic-value-of-long-non-coding-rna-blacat1-in-patients-with-papillary-thyroid-carcinoma
#5
Denghui Liao, Gang Lv, Ting Wang, Jie Min, Yadong Wang, Shengchun Liu
Background: Long noncoding RNAs (lncRNAs) have been reported to have potential diagnostic and prognostic values for numerous cancers. However, the plasma expression of lncRNA BLACAT1 and its clinical value in patients with papillary thyroid cancer (PTC) remain unknown. Methods: The expression profile of BLACAT1 in 87 PTC patients (case group) and 36 patients with nodular goiter (control group) were investigated by qRT-PCR. The Kaplan-Meier method was used for RFS curves, and the univariate survival differences were analyzed by the log-rank test...
2018: Cancer Cell International
https://www.readbyqxmd.com/read/29593806/consequences-of-bleeding-after-thyroid-surgery-analysis-of-7805-operations-performed-in-a-single-center
#6
Beata Wojtczak, Michał Aporowicz, Krzysztof Kaliszewski, Marek Bolanowski
Introduction: Surgical treatment of thyroid gland diseases is associated with the possibility of severe complications. The most dangerous of them is bleeding. Current studies focus on its risk factors, rather than reoperation-related consequences. Material and methods: We analyzed 7805 thyroid operations performed from 1996 to 2014 in the Clinic of General, Gastroenterological and Endocrine Surgery of Wroclaw Medical University. Typical risk factors, symptoms and consequences of bleeding were analyzed...
March 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29593791/histopathological-characterization-and-whole-exome-sequencing-of-ectopic-thyroid-fetal-architecture-in-a-functional-ectopic-gland-from-adult-patient
#7
Rosalinda Yasato Camargo, Cristina Takami Kanamura, Celso Ubirajara Friguglietti, Célia Regina Nogueira, Sonia Iorcansky, Alfio José Tincani, Ana Karina Bezerra, Ester Brust, Fernanda Christtanini Koyama, Anamaria Aranha Camargo, Fernanda Orpinelli R Rego, Pedro Alexandre Favoretto Galante, Geraldo Medeiros-Neto, Ileana Gabriela Sanchez Rubio
Ectopic thyroid results from a migration defect of the developing gland during embryogenesis causing congenital hypothyroidism. But it has also been detected in asymptomatic individuals. This study aimed to investigate the histopathological, functional, and genetic features of human ectopic thyroids. Six samples were histologically examined, and the expression of the specific thyroid proteins was assessed by immunohistochemistry. Two samples were submitted to whole exome sequencing. An oropharynx sample showed immature fetal architecture tissue with clusters or cords of oval thyrocytes and small follicles; one sample exhibited a normal thyroid pattern while four showed colloid goiter...
2018: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29590402/benign-thyroid-diseases-and-risk-of-thyroid-cancer-a-nationwide-cohort-study
#8
Cari M Kitahara, Dóra K Rmendiné Farkas, Jens Otto L Jørgensen, Deirdre Cronin-Fenton, Henrik Toft Sørensen
Context: Thyroid nodules, adenomas, and goiter have consistently been associated with thyroid cancer risk. Few studies have assessed whether thyroid dysfunction and thyroid autoimmunity influence this risk. Objective: To examine thyroid cancer risk following diagnoses of a wide range of benign thyroid conditions. Design: Hospital and cancer registry linkage cohort study for the years 1978-2013. Setting: Nationwide (Denmark)...
March 23, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29589552/evaluation-and-management-of-the-child-with-thyrotoxicosis
#9
Alexander K C Leung, Alexander A C Leung
BACKGROUND: Uncontrolled thyrotoxicosis, especially in early infancy, may cause irreversible damage to the central nervous system as well as profound effects on the function of many organs. Thyrotoxicosis has multiple etiologies and treatment depends on the underlying etiology. An accurate diagnosis is essential so that appropriate treatment can be initiated without undue delay. OBJECTIVE: To review in depth the evaluation, diagnosis, and treatment of children with thyrotoxicosis...
March 26, 2018: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
https://www.readbyqxmd.com/read/29582344/tsh-evaluation-in-hypothyroid-patients-assuming-liquid-levothyroxine-at-breakfast-or-30-min-before-breakfast
#10
I Pirola, E Gandossi, D Brancato, F Marini, A Cristiano, A Delbarba, B Agosti, M Castellano, C Cappelli
PURPOSE: To compare TSH levels of hypothyroid patients treated with liquid LT4 at breakfast or 30 min before breakfast. PATIENTS AND METHODS: Subjects, aged 18-75 years old, were eligible if they presented hypothyroidism, due to Hashimoto's thyroiditis or after thyroidectomy for proven benign goiter. Seven hundred ninety-eight patients were recruited and enrolled in the study. Thirty-seven subjects withdrew from the trial. A total of 761 patients (mean age 46...
March 26, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29581698/letter-to-the-prevalence-of-incidental-thyroid-carcinoma-in-patients-who-underwent-thyroidectomy-for-multinodular-goiter
#11
Mesut Tez
No abstract text is available yet for this article.
February 2018: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29580356/substernal-goiter-correlation-between-grade-and-surgical-approach
#12
Karla V Chávez Tostado, David Velázquez-Fernandez, Mónica Chapa, Juan P Pantoja Millán, Mauricio S Salazar, Miguel F Herrera
Substernal goiter is defined as a thyroid growth beyond the thoracic inlet. Using the cross-section imaging CT system, it can be classified into three grades. The aim of the study was to validate the surgical approach and the occurrence of postoperative complications with substernal goiter extension in our patient population. From a total of 1145 patients who underwent thyroid surgery at our institution in a 15-year period, 60 patients with substernal goiter were included. Clinical features and demographics, degree of extension, surgical details, and complications were analyzed...
February 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29573939/differentiation-of-benign-and-malignant-thyroid-nodules-by-using-comb-push-ultrasound-shear-elastography-a-preliminary-two-plane-view-study
#13
Adriana Gregory, Mahdi Bayat, Viksit Kumar, Max Denis, Bae Hyung Kim, Jeremy Webb, Duane D Meixner, Mabel Ryder, John M Knudsen, Shigao Chen, Mostafa Fatemi, Azra Alizad
RATIONALE AND OBJECTIVES: Low specificity of traditional ultrasound in differentiating benign from malignant thyroid nodules leads to a great number of unnecessary (ie, benign) fine-needle aspiration biopsies that causes a significant financial and physical burden to the patients. Ultrasound shear wave elastography is a technology capable of providing additional information related to the stiffness of tissues. In this study, quantitative stiffness values acquired by ultrasound shear wave elastography in two different imaging planes were evaluated for the prediction of malignancy in thyroid nodules...
March 21, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29553126/potential-use-of-1-25-dihydroxyvitamin-d-in-the-diagnosis-and-treatment-of-papillary-thyroid-cancer
#14
Ting Zhang, Hao Zhang, Liang He, Zhihong Wang, Wenwu Dong, Wei Sun, Ping Zhang
BACKGROUND Low levels of 1-25-dihydroxyvitamin D3 [1,25(OH)2D3] in serum may be a risk factor for several tumor types. Also, high cathelicidin antimicrobial peptide (CAMP) expression is regarded to be important against tumor progression. We evaluated the potential importance of 1,25(OH)2D3 in the diagnosis and treatment of papillary thyroid cancer (PTC). MATERIAL AND METHODS The preoperative serum level of 1,25(OH)2D3 was measured using a double-antibody sandwich enzyme-linked immunosorbent assay. Vitamin D3 receptor (VDR) expression was detected by streptavidin-peroxidase immunohistochemical staining in PTC specimens...
March 19, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29552789/expression-of-human-telomerase-reverse-transcriptase-htert-in-thyroid-neoplasms
#15
Alper Sayiner, Dinc Suren
PURPOSE: Distinction of thyroid neoplasms that include papillary carcinoma (PC) and follicular carcinoma (FC) from benign thyroid neoplasms can be performed successfully by histopathologic examination in most of the cases. However, in some cases it may be difficult to distinct PC and FC as well as FC and follicular adenoma (FA) and also FA and the dominant nodule of multinodular goiter (MNG) histopathologically. In this study, we aimed to determine the role of expression of the human telomerase reverse transcriptase (hTERT) in the distinction of thyroid neoplasms and its relation with prognostic factors by immunohistochemical methods...
January 2018: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29552362/severe-hyperthyroidism-complicated-by-agranulocytosis-treated-with-therapeutic-plasma-exchange-case-report-and-review-of-the-literature
#16
Vishnu Garla, Karthik Kovvuru, Shradha Ahuja, Venkatataman Palabindala, Bharat Malhotra, Sohail Abdul Salim
Aim: To present a case of Graves' disease complicated by methimazole induced agranulocytosis treated with therapeutic plasma exchange (TPE) and review of the literature. Case Presentation: A 21-year-old patient with a history of Graves' disease presented to the endocrine clinic. His history was significant for heat intolerance, weight loss, and tremors. Upon examination he had tachycardia, smooth goiter, thyroid bruit, and hyperactive reflexes. He was started on methimazole and metoprolol and thyroidectomy was to be done once his thyroid function tests normalized...
2018: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/29548512/thyroid-disease-around-the-world
#17
REVIEW
Anastasios Maniakas, Louise Davies, Mark E Zafereo
Thyroid disease is one of the most common pathologies in the world, with two of the most clinically important subgroups being iodine deficiency and thyroid goiter, and thyroid cancer. This review looks at the current state of thyroid disease in the world and evaluates the future direction in terms of thyroid disease treatment and prevention. Several of the most impactful epidemiologic studies are presented and analyzed, as well as a brief overview of the current socioeconomic burden of disease.
March 13, 2018: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/29546048/changes-of-nicotinamide-phosphoribosyltransferase-expressions-in-thyroid-glands-of-patients-with-different-thyroid-pathologies
#18
Nadia Sawicka-Gutaj, Mirosław Andrusiewicz, Agata Czarnywojtek, Joanna Waligórska-Stachura, Maciej Biczysko, Jerzy Skrobisz, Jerzy Sowiński, Marek Ruchała
Purpose: Our aim was to analyze NAMPT expression in thyroid tissue derived from patients with Graves' disease with (GD) and without (GO) orbitopathy, patients with toxic nodular goiters (TNG) and thyroid cancers (TC), and healthy controls. Methods: 153 thyroid tissue samples of consecutive patients who underwent thyroidectomy were collected. Previous therapy with steroids was an exclusion criterion. We collected clinicopathological data of all subjects and we assessed NAMPT expression using qPCR...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29544745/investigation-on-the-factors-that-influence-the-prevalence-of-thyroid-nodules-in-adults-in-tianjin-china
#19
Lili Fan, Long Tan, Yanting Chen, Cong Du, Mei Zhu, Kunling Wang, Hongyan Wei, Wei Wang, Min Gao, Yixin Zhang, Tingkai Cui, Wen Chen, Jun Shen, Wanqi Zhang
Studies have shown that prevalence of thyroid nodules (TNs) has been increasing recently. However, the factors that may influence TN prevalence is not fully understood. In this study, we aimed to understand the prevalence of TNs and identify possible factors that are associated with the prevalence of TNs in Tianjin, China. Subjects aged 18 years or older were randomly collected and all subjects received thyroid ultrasonography, physical examination and questionnaires. Subjects (n = 2647) were divided into the case group in which the subjects had TNs and the control group in which the subjects did not have TNs...
March 8, 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29541194/diagnostic-significance-of-ck19-galectin-3-cd56-tpo-and-ki67-expression-and-braf-mutation-in-papillary-thyroid-carcinoma
#20
Lihua Huang, Xuming Wang, Xuan Huang, Huawei Gui, Yan Li, Qiongxia Chen, Dongling Liu, Lijiang Liu
The aim of the present study was to examine the rate of BRAF mutation and the expression profiles of CK19, galectin-3, CD56, thyroid peroxidase (TPO) and Ki67 in papillary thyroid carcinoma (PTC) and papillary thyroid micro-carcinoma (PTMC). A total of 246 cases of thyroid disease were collected, including PTC, PTMC, nodular goiter (NG) and Hashimoto thyroiditis (HT). The results revealed that CK19 expression was 116/120 in PTC, 61/64 in PTMC, 2/34 in NG and 1/28 in HT. Galectin-3 positive expression was 115/120 in PTC, 60/64 in PTMC, 6/34 in NG and 4/28 in HT...
April 2018: Oncology Letters
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