keyword
https://read.qxmd.com/read/36125393/acute-kidney-injury-from-presumptive-intramural-ureteral-hemorrhage-secondary-to-diphacinone-rodenticide-exposure-in-a-dog
#21
Nadene Oliver, Kaila Rizzo, Saya Press, Stephanie Istvan
OBJECTIVE: To describe the clinical features and outcome of a dog with anticoagulant rodenticide (diphacinone) exposure, which was subsequently diagnosed with a coagulopathy characterized by hemoperitoneum, and presumptive ureteral wall hemorrhage contributing to acute kidney injury (AKI). CASE SUMMARY: A 4-year-old, female neutered Australian Cattle Dog was evaluated for an acute onset of lethargy, decreased appetite, and a mild right thoracic limb lameness. Radiographs and point of care ultrasound demonstrated retroperitoneal and peritoneal effusion...
September 20, 2022: Journal of Veterinary Emergency and Critical Care
https://read.qxmd.com/read/36002297/leptospirosis-with-multiple-organ-dysfunction-in-a-mongoose-scat-detection-dog-infected-with-leptospira-interrogans-serogroup-hebdomadis-okinawa-japan
#22
JOURNAL ARTICLE
Tetsuya Kakita, Maki Yamagishi, Sugao Oshiro, Chisako Oyakawa, Takashi Nagamine, Tsuyoshi Kudeken, Hisako Kyan, Nobuo Koizumi
A 2-year-old male mongoose-scat-detection dog was diagnosed with leptospirosis by urine PCR. The patient developed acute renal failure, hepatic dysfunction, and disseminated intravascular coagulation. Treatment with antibiotics was administered, including ampicillin and doxycycline, and supportive care management was provided. Seroconversion against serogroup Hebdomadis was observed on day 8. The leptospiral gene flaB was detected only in urine collected on day 1, from which Leptospira interrogans ST329 was identified by multilocus sequence typing using seven housekeeping genes...
August 25, 2022: Journal of Veterinary Medical Science
https://read.qxmd.com/read/35679242/cohort-profile-the-golden-retriever-lifetime-study-grls
#23
JOURNAL ARTICLE
Julia Labadie, Brenna Swafford, Mara DePena, Kathy Tietje, Rodney Page, Janet Patterson-Kane
The aim of this article is to provide a detailed description of the Golden Retriever Lifetime Study (GRLS), a prospective cohort study investigating nutritional, environmental, lifestyle, and genetic risk factors for cancer and other common diseases in dogs. Primary outcomes of interest include hemangiosarcoma, lymphoma, osteosarcoma, and high-grade mast cell tumors. Secondary outcomes of interest include other cancers, hypothyroidism, epilepsy, atopy, otitis externa, hip dysplasia, heart failure, and renal failure...
2022: PloS One
https://read.qxmd.com/read/35478193/long-term-outcome-of-dogs-recovering-from-acute-kidney-injury-132-cases
#24
JOURNAL ARTICLE
Mali Bar-Nathan, Hilla Chen, Dar Rimer, Gilad Segev
BACKGROUND: Information regarding long-term outcome of dogs recovering from acute kidney injury (AKI) is limited. OBJECTIVES: Determine the long-term outcome of dogs recovering from AKI and identify predictors for serum creatinine concentration (sCr) normalization and long-term outcome. ANIMALS: One hundred thirty-two dogs with AKI that survived ≥30 days postdischarge. METHODS: Retrospective study. Search of medical records of dogs diagnosed with AKI that survived to discharge...
May 2022: Journal of Veterinary Internal Medicine
https://read.qxmd.com/read/35355772/clinical-applications-of-substance-p-neurokinin-1-receptor-antagonist-in-canine-medicine
#25
REVIEW
K Sharun, K Jambagi, M Arya, Aakanksha, S N Chaithra, P K Patel, S K Dixit, K Dhama
Substance P binds to the Neurokinin-1 (NK-1) receptors found in the emetic center of the central nervous system (CNS) to induce emesis. Maropitant is a selective NK-1 receptor antagonist that inhibits the binding of substance P to NK-1 receptors and is commonly used to prevent and treat vomiting in dogs. This review study aimed to discuss and analyze the therapeutic potential of substance P (Neurokinin-1 receptor) antagonist with a particular focus on the drug maropitant in canine medicine. A systematic literature review was performed to identify the existing literature on the subject during the past 20 years (2001-2021) using such databases as ScienceDirect, PubMed, Scopus, and Google Scholar...
November 2021: Archives of Razi Institute
https://read.qxmd.com/read/35103347/acute-kidney-injury-in-dogs-etiology-clinical-and-clinicopathologic-findings-prognostic-markers-and-outcome
#26
JOURNAL ARTICLE
Dar Rimer, Hilla Chen, Mali Bar-Nathan, Gilad Segev
BACKGROUND: Acute kidney injury (AKI) is a common, potentially fatal condition. OBJECTIVES: To characterize the etiologies, clinical and clinicopathologic findings, hospitalization period, and outcome of dogs with AKI and to identify markers of negative prognosis. ANIMALS: Two hundred forty-nine client-own dogs diagnosed with AKI and hospitalized at a veterinary teaching hospital. METHODS: Retrospective study. Search of medical records for dogs with AKI...
March 2022: Journal of Veterinary Internal Medicine
https://read.qxmd.com/read/34941094/bordetella-bronchiseptica-infections-in-patients-with-hiv-aids-a-case-report-and-review-of-the-literature
#27
JOURNAL ARTICLE
Veena R Gujju, Bushra Akram, Dena R Shibib, Miranda A McGhee, Douglas A Drevets
RATIONALE: Bordetella bronchiseptica is a common cause of upper respiratory tract infections in domesticated dogs and cats and a rare zoonotic pathogen in immunocompromised humans. With increasing numbers of people acquiring pets and spending time with them in confined spaces due to COVID-19 lockdowns, it is important to be aware of adverse health consequences brought about by this interaction. We present a case of B bronchiseptica pneumonia in a patient with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) and review key characteristics of an additional 30 cases of B bronchiseptica infections in 29 patients with HIV/AIDS that were identified by literature review...
December 23, 2021: Medicine (Baltimore)
https://read.qxmd.com/read/34940602/evaluation-of-serum-and-urine-amino-acids-in-dogs-with-chronic-kidney-disease-and-healthy-dogs-fed-a-renal-diet
#28
JOURNAL ARTICLE
Marcio Antonio Brunetto, Doris Pereira Halfen, Larissa Wunsche Risolia, Vivian Pedrinelli, Douglas Segalla Caragelasco, Thiago Henrique Annibale Vendramini, Julio César de Carvalho Balieiro, Cristiana Fonseca Ferreira Pontieri, Juliana Toloi Jeremias, Bruna Ruberti, Marcia Mery Kogika
This observational study aimed to evaluate serum and urinary amino acid (AA) concentrations in healthy dogs and dogs with chronic kidney disease (CKD) fed a commercial therapeutic renal diet with reduced protein and phosphorus levels. Ten dogs with CKD stages 3 or 4 composed the study group and received the renal diet for 180 days (RG T180). A control group (CG T30) composed of seven healthy dogs was fed a renal diet for 30 days. When comparing serum AA between RG T180 and CG T30, histidine, isoleucine, leucine, lysine, phenylalanine, tryptophan, cysteine, citrulline, ornithine, taurine, branched-chain amino acids (BCAA), and total essential amino acids (EAA) were higher in RG T180...
December 6, 2021: Metabolites
https://read.qxmd.com/read/34879085/glomerulotubular-pathology-in-dogs-with-subclinical-ehrlichiosis
#29
JOURNAL ARTICLE
Leandro Zuccolotto Crivellenti, Cristiane Alves Cintra, Suellen Rodrigues Maia, Gyl Eanes Barros Silva, Sofia Borin-Crivellenti, Rachel Cianciolo, Christopher A Adin, Mirela Tinucci-Costa, Caio Santos Pennacchi, Aureo Evangelista Santana
Subclinical stage of ehrlichiosis is characterized by absence of clinical or laboratory alterations; however, it could lead to silent glomerular/tubular changes and contribute significantly to renal failure in humans and animals. The aim of this study was to evaluate glomerular and tubular alterations in dogs with subclinical ehrlichiosis. We evaluated renal biopsies of 14 bitches with subclinical ehrlichiosis and 11 control dogs. Samples were obtained from the left kidney, and the tissue obtained was divided for light microscopy, immunofluorescence, and transmission electron microscopy...
2021: PloS One
https://read.qxmd.com/read/34820434/cystatin-c-and-iris-advances-in-the-evaluation-of-kidney-function-in-critically-ill-dog
#30
JOURNAL ARTICLE
Fabiola de Oliveira Paes-Leme, Eliana M Souza, Paulo Ricardo Oliveira Paes, Maderleine Geisa Gomes, Felipe Santos Muniz, Marco Túlio Gomes Campos, Renata Barbosa Peixoto, Patricia Donado Vaz de Melo, Marcio H L Arndt, Adriane Costa Val
Critically ill hospitalized dogs are subject to certain complications, being acute kidney injury (AKI) a common one. Early diagnosis is crucial, and Cystatin C (CysC) is a reliable and early biomarker. The International Society of Renal Interest (IRIS) states that AKI severity can be assessed by mild changes in creatinine serum levels or reduction of urine output that cannot be considered biomarkers of renal injury but failure or insufficiency. Twenty-eight dogs admitted to the Intensive Care Unit under risk factors for the development of AKI were evaluated...
2021: Frontiers in Veterinary Science
https://read.qxmd.com/read/34722194/a-retrospective-study-of-14-dogs-with-advanced-heart-failure-treated-with-loop%C3%A2-diuretics-and-hydrochlorothiazide
#31
JOURNAL ARTICLE
Koji Iwanaga, Ryuji Araki, Mitsuhiro Isaka
BACKGROUND: The use of thiazide diuretics is recommended in the American College of Veterinary Internal Medicine guidelines for advanced heart failure due to mitral insufficiency (MI) in dogs. However, there are no large-scale reports of the use of thiazide diuretics in dogs with advanced heart failure. AIM: This retrospective study evaluated the therapeutic effect of concomitant hydrochlorothiazide (HTCZ) with loop diuretics in dogs with heart failure. METHODS: The study included 14 dogs diagnosed with advanced pulmonary edema with MI at two facilities...
2021: Open Veterinary Journal
https://read.qxmd.com/read/34604374/plasmatic-dimethylarginines-in-dogs-with-myxomatous-mitral-valve-disease
#32
JOURNAL ARTICLE
Carlotta Valente, Carlo Guglielmini, Marco Baron Toaldo, Giovanni Romito, Carlo Artusi, Laura Brugnolo, Barbara Contiero, Helen Poser
Plasmatic dimethylarginines, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) are considered biomarkers of endothelial and renal dysfunction, respectively, in humans. We hypothesize that plasmatic concentration of dimethylarginines in dogs with myxomatous mitral valve disease (MMVD) is influenced by heart disease stage. Eighty-five client-owned dogs with MMVD, including 39, 19, and 27 dogs in ACVIM stages B1, B2, and C+D, respectively, and a control group of 11 clinically healthy dogs were enrolled...
2021: Frontiers in Veterinary Science
https://read.qxmd.com/read/34578137/first-autochthonous-infection-of-a-cat-with-dirofilaria-immitis-in-austria
#33
Lisa-Maria Kulmer, Maria Sophia Unterköfler, Hans-Peter Fuehrer, Varvara Janovska, Matus Pagac, Michaela Svoboda, Luigi Venco, Michael Leschnik
This case report is about a seven-year-old male neutered European Shorthair cat infected by Dirofilaria immitis as the first reported autochthonous Dirofilaria immitis infection in Austria. There was no history of periods abroad. Echocardiography showed suspected D. immitis in the right cardiac chamber with increased pulmonary pressure and ascites. Surgical removal of the heartworms was performed. Twenty adult heartworms were removed by transvenous jugular approach under general anesthesia and stored in 4% formalin...
August 30, 2021: Pathogens
https://read.qxmd.com/read/34548653/sgc-stimulation-lowers-elevated-blood-pressure-in-a-new-canine-model-of-resistant-hypertension
#34
JOURNAL ARTICLE
Julia Vogel, Philip Boehme, Susanne Homann, Mario Boehm, Katharina Andrea Schütt, Katharina Boden, Jakob Balitzki, Jörg Hüser, Wilfried Dinh, Hubert Truebel, Peter Sandner, Thomas Mondritzki
Therapy-resistant hypertension is a serious medical problem, causing end-organ damage, stroke, and heart failure if untreated. Since the standard of care fails in resistant hypertension patients, there is still a substantial unmet medical need for effective therapies. Active stimulation of soluble guanylyl cyclase via novel soluble guanylyl cyclase stimulators might provide an effective treatment option. To test this hypothesis, we established a new experimental dog model and investigated the effects of the soluble guanylyl cyclase-stimulator BAY 41-2272...
September 22, 2021: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://read.qxmd.com/read/34391445/emergence-of-babesia-conradae-infection-in-coyote-hunting-greyhounds-in-oklahoma-usa
#35
JOURNAL ARTICLE
Erin Stayton, Megan Lineberry, Jennifer Thomas, Tina Bass, Kelly Allen, Ramaswamy Chandrashekar, Gene Yost, Mason Reichard, Craig Miller
BACKGROUND: Babesia species are intraerythrocytic Apicomplexan parasites that infect a wide range of vertebrate hosts. These pathogens are typically transmitted either by tick vectors or by direct blood-to-blood contact, and may cause life-threatening clinical disease, such as thrombocytopenia, hemolytic anemia and acute renal failure, in canine hosts. While Babesia vogeli and Babesia gibsoni infections have both been reported in Oklahoma, reports of Babesia conradae infections have been limited to California...
August 14, 2021: Parasites & Vectors
https://read.qxmd.com/read/34387901/retrospective-evaluation-of-a-dose-dependent-effect-of-angiotensin-converting-enzyme-inhibitors-on-long-term-outcome-in-dogs-with-cardiac-disease
#36
JOURNAL ARTICLE
Jessica L Ward, Yen-Yu Chou, Lingnan Yuan, Karin S Dorman, Jonathan P Mochel
BACKGROUND: Angiotensin-converting enzyme inhibitors (ACEIs) are commonly prescribed in dogs, but the ideal dosage is unknown. HYPOTHESIS/OBJECTIVES: In dogs with cardiac disease, a dose-response relationship exists for ACEIs with respect to long-term outcome. ANIMALS: One hundred forty-four dogs with cardiac disease, 63 with current or prior congestive heart failure. METHODS: Retrospective medical record review. Cox proportional hazards models were used to determine variables associated with 2-year survival or survival from first-onset congestive heart failure (CHF)...
September 2021: Journal of Veterinary Internal Medicine
https://read.qxmd.com/read/34315691/prospective-clinical-trial-evaluating-spironolactone-in-doberman-pinschers-with-congestive-heart-failure-due-to-dilated-cardiomyopathy
#37
JOURNAL ARTICLE
A Laskary, S Fonfara, H Chambers, M L O'Sullivan
INTRODUCTION/OBJECTIVES: Whether the aldosterone antagonist spironolactone has beneficial survival effects in dogs with dilated cardiomyopathy (DCM) is not known. The primary objective of the study was to evaluate the effect of spironolactone, when added to conventional therapy, on survival time in Doberman pinschers with congestive heart failure (CHF) due to DCM. ANIMALS: Sixty-seven client-owned Doberman pinschers with CHF due to DCM. MATERIALS AND METHODS: The trial design was prospective, randomized, blinded, and placebo controlled...
June 25, 2021: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://read.qxmd.com/read/34297883/clinical-outcomes-and-prognostic-factors-associated-with-nonsteroidal-anti-inflammatory-drug-overdose-in-dogs-presented-to-an-emergency-room
#38
JOURNAL ARTICLE
Cara Steele, Darko Stefanovski, Mark P Rondeau
OBJECTIVE: To describe case presentations, clinical signs, and outcomes following nonsteroidal anti-inflammatory drug (NSAID) overdose in a clinical population of dogs and to identify factors associated with various outcomes including death or euthanasia, acute kidney injury, and suspected gastrointestinal ulceration (GIU). DESIGN: Retrospective study. SETTING: University teaching hospital. ANIMALS: One hundred twenty-five client-owned dogs presenting to an emergency room for NSAID overdose between January 2006 and December 2017...
July 23, 2021: Journal of Veterinary Emergency and Critical Care
https://read.qxmd.com/read/34055517/a-bite-so-bad-septic-shock-due-to-capnocytophaga-canimorsus-following-a-dog-bite
#39
Michelle-Ashley Rizk, Nicholas Abourizk, Kinjal P Gadhiya, Panupong Hansrivijit, John D Goldman
Infection by Capnocytophaga canimorsus (C. canimorsus) , a Gram-negative rod found in the normal oral flora of canine and feline species and transmitted through bites or scratches, is a rare phenomenon. Infections most commonly occur in alcoholics and immunocompromised patients. In this report, we describe the case of a middle-aged male with a history of alcohol abuse who presented with septic shock and multisystem organ failure following a suspected dog bite. The patient was a 59-year-old Caucasian male with alcohol abuse disorder who initially presented with encephalopathy and lethargy...
April 24, 2021: Curēus
https://read.qxmd.com/read/34052958/renal-revascularization-by-a-pedicled-intestinal-segment-wrapping-the-kidney-a-new-method-for-kidney-revascularization
#40
JOURNAL ARTICLE
Hossein Hodjati, Seyed Masood Moosavi, Ahmad Hosseinzadeh, Mohammad Hossein Anbardar, Shaghayegh Sherafatmand, Khalil Kazemnia, Hamidreza Hosseinpour, Reza Shahriarirad
BACKGROUND: Renal artery stenosis is caused by a heterogeneous group of diseases, including atherosclerosis and fibromuscular dysplasia, which can be treated medically, via endovascular techniques, or by open revascularization; however, satisfactory and effective results are not always obtained. We aimed to assess the possibility of renal revascularization by a pedicled intestinal segment wrapping the kidney. METHODS: Five dogs were operated on at three steps. At the first step, laparotomy was performed, and the right kidney was released...
May 29, 2021: International Urology and Nephrology
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