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Dog renal failure

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https://www.readbyqxmd.com/read/28831382/capnocytophaga-canimorsus-sepsis-in-a-methotrexate-treated-patient-with-rheumatoid-arthritis
#1
Shinobu Tamura, Asumi Koyama, Yusuke Yamashita, Chieko Shiotani, Hiromichi Nakamoto, Chiaki Nakamoto, Michio Suzuki, Yoshio Nakano, Koichi Imaoka, Takashi Sonoki, Tokuzo Fujimoto
Capnocytophaga canimorsus is a gram-negative rod that can be transmitted primarily by dog bites. This life-threatening organism commonly causes sepsis in patients with splenectomy or alcoholism. A 53-year-old rheumatoid arthritis male treated with methotrexate (MTX) for 5 years was admitted for a 4-day history of fever and dyspnea. He had been bitten on a finger by the family dog 4 days before onset. Laboratory tests revealed pancytopenia, acute renal failure, and evidence of disseminated intravascular coagulation, and he subsequently developed acute respiratory distress syndrome...
2017: IDCases
https://www.readbyqxmd.com/read/28747096/preliminary-description-of-aging-cats-and-dogs-presented-to-a-new-zealand-first-opinion-veterinary-clinic-at-end-of-life
#2
M C Gates, H J Hinds, A Dale
AIMS To conduct a preliminary investigation into the chronic disease conditions and clinical signs present in aging New Zealand companion animals at end-of-life and to describe the timing, circumstances, and manner of death. METHODS The medical records database of a first-opinion, companion animal, veterinary practice in Auckland, New Zealand was searched to identify all canine and feline patients ≥7 years of age that were subjected to euthanasia or cremated in the period between July 2012-June 2014. The free-text medical notes were analysed for information on the circumstances surrounding the death, previous diagnoses of chronic disease conditions, and the presence of clinical signs associated with decreased quality-of-life at the time of euthanasia...
August 9, 2017: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/28669137/effects-of-benazepril-on-survival-of-dogs-with-chronic-kidney-disease-a-multicenter-randomized-blinded-placebo-controlled-clinical-trial
#3
J N King, A Font, J-F Rousselot, R A Ash, U Bonfanti, C Brovida, I D Crowe, D Lanore, D Pechereau, W Seewald, G Strehlau
BACKGROUND: Chronic kidney disease (CKD) is an important cause of morbidity and mortality in dogs. OBJECTIVE: To evaluate the efficacy in prolonging survival and safety of benazepril administration to dogs with CKD. ANIMALS: Forty-nine client-owned dogs with CKD. METHODS: Dogs were randomized to benazepril (0.25 to <0.5 mg/kg) or placebo once daily for up to 2 years in a prospective, multicenter, blinded clinical trial...
July 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28461132/a-non-contrast-cmr-index-for-assessing-myocardial-fibrosis
#4
Qian Yin, Dana Abendschein, David Muccigrosso, Robert O'Connor, Thomas Goldstein, Ridong Chen, Jie Zheng
PURPOSE: Safe, sensitive, and non-invasive imaging methods to assess the presence, extent, and turnover of myocardial fibrosis are needed for early stratification of risk in patients who might develop heart failure after myocardial infarction. We describe a non-contrast cardiac magnetic resonance (CMR) approach for sensitive detection of myocardial fibrosis using a canine model of myocardial infarction and reperfusion. METHODS: Seven dogs had coronary thrombotic occlusion of the left anterior descending coronary arteries followed by fibrinolytic reperfusion...
April 28, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28321811/interleukin-2-old-and-new-approaches-to-enhance-immune-therapeutic-efficacy
#5
REVIEW
Pooja Dhupkar, Nancy Gordon
Interleukin-2 (IL-2) is a very well-known cytokine that has been studied for the past 35 years. It plays a major role in the growth and proliferation of many immune cells such NK and T cells. It is an important immunotherapy cytokine for the treatment of various diseases including cancer. Systemic delivery of IL-2 has shown clinical benefit in renal cell carcinoma and melanoma patients. However, its use has been limited by the numerous toxicities encountered with the systemic delivery. Intravenous IL-2 causes the well-known "capillary leak syndrome," or the leakage of fluid from the circulatory system to the interstitial space resulting in hypotension (low blood pressure), edema, and dyspnea that can lead to circulatory shock and eventually cardiopulmonary collapse and multiple organ failure...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28224456/zinc-toxicosis-in-a-boxer-dog-secondary-to-ingestion-of-holiday-garland
#6
Karyn Bischoff, Anne Chiapella, Jaime Weisman, Lisa M Crofton, Joseph Hillebrandt
INTRODUCTION: Increased admissions occur in small animal veterinary emergency clinics during some holidays, and some of the increased caseload is due to ingestion of toxic substances. This report documents zinc toxicosis contributing to the death of a dog after ingestion of holiday tinsel garland. CASE STUDY: A mature boxer dog presented with a 4-day history of vomiting and diarrhea. Radiodense foreign material was detected in the stomach and removed via gastrotomy...
February 21, 2017: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/28155296/paraquat-intoxication-and-associated-pathological-findings-in-three-dogs-in-south-africa
#7
June H Williams, Zandri Whitehead, Erna Van Wilpe
Paraquat is a bipyridylium non-selective contact herbicide commonly used worldwide. When ingestion occurs by humans and animals either accidentally, intentionally or maliciously, paraquat selectively accumulates in the lungs resulting in the production of oxygen-free radicals, causing membrane damage and cell death. Intoxicated subjects typically show progressive and fatal pulmonary haemorrhage, collapse and oedema. In individuals surviving the acute phase, pulmonary fibrosis develops. Gastrointestinal-, renal- and central nervous system clinical signs may also occur...
November 9, 2016: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/28074976/utility-of-urinary-markers-in-the-assessment-of-renal-dysfunction-in-canine-babesiosis
#8
Dagmara Winiarczyk, Łukasz Adaszek, Michał Bartnicki, Beata Abramowicz, Paweł Łyp, Jacek Madany, Stanisław Winiarczyk
OBJECTIVE: Canine babesiosis is a common and clinically significant tick-borne disease caused by haemoprotozoan parasites of the genus Babesia. Acute renal failure is considered to be one of the most prevalent complications of canine babesiosis. This complication leads to a decrease in the glomerular filtration rate and in consequence causes azotemia and uremia. The objective of this study was to assess the localization and extent of renal damage in dogs infected with Babesia canis using an urinary marker for glomerular (urinary immunoglobulin G, uIgG), proximal tubular dysfunction (urinary retinol binding protein, uRBP) and distal tubular dysfunction (urinary Tamm-Horsfal protein, uTHP)...
April 19, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/27934626/management-of-a-growing-dog-with-renal-failure-fed-a-homemade-diet
#9
K Gerstner, A Liesegang
No abstract text is available yet for this article.
December 2016: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/27892876/low-expression-of-cyclooxygenase-2-in-chronic-kidney-disease-in-young-dogs
#10
Akira Yabuki, Akiko Miyazaki, Osamu Ichii, Moeko Kohyama, Mariko Sawa, Osamu Yamato
Chronic kidney disease (CKD) often results in end-stage renal failure in young dogs; however, the pathogenesis of this disease is not established. This study investigated renal expression of cyclooxygenase (COX)-1 and COX-2 proteins in three dogs with chronic kidney disease by immunohistochemistry. Histopathology showed asynchronous differentiation of renal tissues, including immature glomeruli. COX-1 signals were not detected in diseased or normal kidneys. COX-2 signals were low or undetectable in diseased kidneys, while normal kidneys showed clear positive signals in the macula densa (MD)...
December 2016: Research in Veterinary Science
https://www.readbyqxmd.com/read/27758811/left-atrial-remodeling-and-atrioventricular-coupling-in-a-canine-model-of-early-heart-failure-with-preserved-ejection-fraction
#11
Rosita Zakeri, Gilles Moulay, Qiang Chai, Ozgur Ogut, Saad Hussain, Hiroyuki Takahama, Tong Lu, Xiao-Li Wang, Wolfgang A Linke, Hon-Chi Lee, Margaret M Redfield
BACKGROUND: Left atrial (LA) compliance and contractility influence left ventricular stroke volume. We hypothesized that diminished LA compliance and contractile function occur early during the development of heart failure with preserved ejection fraction (HFpEF) and impair overall cardiac performance. METHODS AND RESULTS: Cardiac magnetic resonance imaging, echocardiography, left ventricular and LA pressure-volume studies, and tissue analyses were performed in a model of early HFpEF (elderly dogs, renal wrap-induced hypertension, exogenous aldosterone; n=9) and young control dogs (sham surgery; n=13)...
October 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27725349/evaluation-of-serum-cystatin-c-and-symmetric-dimethylarginine-concentrations-in-dogs-with-heart-failure-from-chronic-mitral-valvular-insufficiency
#12
Bom-Sul Choi, Hyeong-Sun Moon, Sang-Hyuk Seo, Changbaig Hyun
Reduction in glomerular filtration rate (GFR) is a common complication in advanced stages of heart failure (HF). The convenient and precise assessment for GFR would be useful for early detection of renal impairment in HF dogs. Our hypothesis of this study was the GFR would be reduced in advanced stages of HF from chronic mitral valvular insufficiency (CMVI), as indicated by renal markers including serum cystatin-C (Cys-C) and symmetric dimethylarginine (SDMA) concentrations. Forty-three client-owned dogs consisting of 33 dogs with different stages of HF from CMVI and 10 age-matched healthy dogs were enrolled in this study...
January 20, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/27717188/preliminary-investigation-of-cardiovascular-renal-disorders-in-dogs-with-chronic-mitral-valve-disease
#13
E Martinelli, C Locatelli, S Bassis, S Crosara, S Paltrinieri, P Scarpa, I Spalla, A M Zanaboni, C Quintavalla, P Brambilla
BACKGROUND: Veterinary literature lacks data about cardiovascular-renal disorders (CvRD) and cardiorenal-anemia syndrome (CRAS) in dogs. HYPOTHESIS: A direct correlation exists between ACVIM class and IRIS stage; chronic kidney disease (CKD) complicates chronic mitral valve disease (CMVD) more often than does anemia in dogs. ANIMALS: One hundred and fifty-eight client-owned dogs with CMVD. METHODS: Signalment, physical examination findings, electrocardiography, thoracic radiographs, echocardiography, and blood analysis were retrospectively evaluated to assess the prevalence of CKD and anemia in dogs with CMVD and to investigate the relationships among ACVIM class, IRIS stage, and survival...
September 2016: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/27692098/effects-of-choline-treatment-in-concentrations-of-serum-matrix-metalloproteinases-mmps-mmp-tissue-inhibitors-timps-and-immunoglobulins-in-an-experimental-model-of-canine-sepsis
#14
Meric Kocaturk, Oya Eralp-Inan, A Tvarijonaviciute, Mehmet Cansev, M Ozgur Ozyigit, J J Ceron, Zeki Yilmaz, M Mufit Kahraman
The aim of the present study was to investigate effects of intravenous (i.v.) choline treatment on serum matrix metalloproteinases (MMP), MMP tissue inhibitors (TIMP) and immunoglobulins (Igs), and to determine if there were relations between serum MMPs/TIMPs and C-reactive protein (CRP) (as a marker of the acute phase response), immunoglobulin G and M (IgG and IgM) (as a maker of the Ig responses) and markers of organ damage such as muscular damage (creatine phosphokinase, [CPK]), liver damage (alanine aminotransferase [ALT]) and renal dysfunction (blood urea nitrogen [BUN] and creatinine, [Cr]) in dogs with endotoxemia...
November 1, 2016: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/27641998/aspergillus-spp-panophthalmitis-with-intralenticular-invasion-in-dogs-report-of-two-cases
#15
Penelope J Wooff, Darryl D Dees, Leandro Teixeria
This case series describes the ocular, clinical and histologic manifestations of disseminated Aspergillosis in two dogs. Two dogs presented for severe unilateral panophthalmitis and secondary glaucoma with positive Aspergillus spp. titers. Case 1 showed no clinicopathologic systemic symptoms of fungal dissemination, however, case 2 was affected with acute renal failure. The affected eye of case 1 did not respond to medical therapy and was enucleated for comfort. The affected eye of case 2 responded to aggressive topical and systemic medical therapies, however, the patient was euthanized for acute renal failure...
September 19, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27595920/the-prevalence-of-dirofilaria-repens-in-cats-healthy-dogs-and-dogs-with-concurrent-babesiosis-in-an-expansion-zone-in-central-europe
#16
Anna Bajer, Anna Rodo, Ewa J Mierzejewska, Katarzyna Tołkacz, Renata Welc-Faleciak
BACKGROUND: Dirofilaria repens is a mosquito-transmitted, filarial nematode parasitizing dogs, cats and other carnivores. Recently, this parasite has spread in central Europe, including Poland. The aim of the present study was to estimate the prevalence of D. repens in cats and dogs in different regions of the country and to investigate the occurrence and consequences of co-infection with another fast-spreading vector-borne parasite, Babesia canis. RESULTS: In the period 2013-2015, 147 blood samples from cats from central Poland and 257 blood samples from dogs from central, northern, southern and western Poland were collected...
September 5, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27555054/efficacy-and-safety-of-renal-sympathetic-denervation-on-dogs-with-pressure-overload-induced-heart-failure
#17
Pingan Chen, Shuilong Leng, Yishan Luo, Shaonan Li, Zicheng Huang, Zhenxi Liu, Zhen Liu, Jie Wang, Xiaoming Lei
BACKGROUND: In dogs with heart failure (HF) induced by overload pressure, the role of renal sympathetic denervation (RSD) on heart failure and in the renal artery is unclear. Therefore, we investigated the efficacy and safety of RSD in dogs with pressure overload-induced heart failure. METHODS: Twenty mongrel dogs were divided into a sham-operated group, an HF group and an HF + RSD group. In the sham-operated group, the abdominal aorta was located but was not constricted, in the HF group, the abdominal aorta was constricted without RSD, and the HF+RSD group underwent RSD with constriction of the abdominal aorta after 10 weeks...
February 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27543449/shaggy-lame-fox-syndrome-in-pribilof-island-arctic-foxes-alopex-lagopus-pribilofensis-alaska
#18
T R Spraker, P A White
A previously unrecognized condition is described in wild free-ranging Pribilof arctic foxes ( Alopex lagopus pribilofensis) from the Pribilof Islands, Alaska, USA. This condition is called shaggy lame fox syndrome (SLFS) denoting the primary clinical signs first observed. Criteria used to suspect SLFS on gross examination included emaciation, failure to shed winter pelage and moderate to severe polyarthritis. Criteria used to confirm SLFS histologically included polyarthritis (characterized by lymphoplasmacytic synovitis, tenosynovitis, bursitis, periosteal bony proliferation, and periarticular lymphoplasmacytic vasculitis) and systemic leukocytoclastic vasculitis...
March 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/27539305/risk-factors-for-invasive-pasteurellosis-a-retrospective-case-study
#19
V Nollet, L Souply, B Rosolen, M Mohseni-Zadeh, M Martinot
Pasteurellosis is a frequent zoonosis mainly transmitted by cats and dogs. Invasive forms of pasteurellosis are associated with significant morbidity and mortality. This retrospective study aimed to highlight risk factors (RFs) for invasive pasteurellosis. We included patients with positive Pasteurella samples. The clinical forms were classified as invasive or local pasteurellosis. We evaluated 13 RFs: age, sex, alcohol use, tobacco use, chronic liver disease, chronic renal failure, diabetes, chronic cardiovascular disease, chronic pulmonary disease, chronic inflammatory disease, chronic osteoarticular disease, immunosuppression, and progressive cancers...
December 2016: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27510812/renal-failure-in-dogs-kept-by-a-man-with-severe-psoriasis
#20
LETTER
Y Fujita, K Hanazono, E Uchida, T Kawahata, A Suto, K Nakamura, H Shimizu
No abstract text is available yet for this article.
April 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
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