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https://www.readbyqxmd.com/read/28549491/increased-chondrocyte-apoptosis-in-kashin-beck-disease-and-rats-induced-by-t-2-toxin-and-selenium-deficiency
#1
Hao Jie Yang, Ying Zhang, Zhi Lun Wang, Sen Hai Xue, Si Yuan Li, Xiao Rong Zhou, Meng ZHANGg, Qian Fang, Wen Jun Wang, Chen Chen, Xiang Hua Deng, Jing Hong Chen
OBJECTIVE: To investigate chondrocyte apoptosis and the expression of biochemical markers associated with apoptosis in Kashin-Beck disease (KBD) and in an established T-2 toxin- and selenium (Se) deficiency-induced rat model. METHODS: Cartilages were collected from the hand phalanges of five patients with KBD and five healthy children. Sprague-Dawley rats were administered a selenium-deficient diet for 4 weeks prior to T-2 toxin exposure. The apoptotic chondrocytes were observed by terminal deoxynucleotidyl transferase dUTP nick end labeling staining...
May 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28547854/nucleus-accumbens-functional-connectivity-at-age-20-is-associated-with-trajectory-of-adolescent-cannabis-use-and-predicts-psychosocial-functioning-in-young-adulthood
#2
Sarah D Lichenstein, Samuel Musselman, Daniel S Shaw, Stephanie Sitnick, Erika E Forbes
AIMS: To identify trajectories of cannabis use across adolescence, 2) to measure the influence of cannabis use characteristics on functional connectivity of the nucleus accumbens (NAcc), and 3) to assess whether patterns of functional connectivity related to cannabis use are associated with psychosocial functioning 2 years later. DESIGN: The Pitt Mother & Child Project (PMCP) is a prospective, longitudinal study of male youth at high risk for psychopathology based on family income and gender...
May 26, 2017: Addiction
https://www.readbyqxmd.com/read/28547736/rice-bran-metabolome-contains-amino-acids-vitamins-cofactors-and-phytochemicals-with-medicinal-and-nutritional-properties
#3
Iman Zarei, Dustin G Brown, Nora Jean Nealon, Elizabeth P Ryan
BACKGROUND: Rice bran is a functional food that has shown protection against major chronic diseases (e.g. obesity, diabetes, cardiovascular disease and cancer) in animals and humans, and these health effects have been associated with the presence of bioactive phytochemicals. Food metabolomics uses multiple chromatography and mass spectrometry platforms to detect and identify a diverse range of small molecules with high sensitivity and precision, and has not been completed for rice bran...
December 2017: Rice
https://www.readbyqxmd.com/read/28545589/gastrointestinal-tolerance-of-low-fodmap-oral-nutrition-supplements-in-healthy-human-subjects-a-randomized-controlled-trial
#4
Jennifer Erickson, Renee Korczak, Qi Wang, Joanne Slavin
BACKGROUND: There has been increasing interest in utilizing a diet low in fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) for the treatment of irritable bowel syndrome (IBS), a functional gastrointestinal disease. While studies have indicated that this diet can be effective at symptom reduction, it is a restrictive diet and patients may find it challenging to find low FODMAP products to meet their nutrient needs. The primary objective of this study was to assess the gastrointestinal (GI) tolerance of three low FODMAP oral nutrition supplements (ONS) in healthy adults...
May 25, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28545376/nutrition-as-a-health-determinant-in-elderly-patients
#5
Ignazio Grattagliano, Tecla Mastronuzzi
An adequate caloric intake is a major determinant for the health status especially when degenerative conditions become a predominant risk for difficult-to-treat diseases as in aging. The maintenance of the nutritional status is the best measure to counteract the risk of protein-caloric malnutrition and its complications which often sneakily affects elderly population and in particular frail patients. Both organic and social risk factors [economic hardship, loneliness, institutionalization] are important as determining causes...
May 23, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28545368/improving-metabolic-control-through-functional-foods
#6
John G Jones, Joao C P Silva
Functional foods are designed to have physiological benefits and/or reduce the risk of chronic disease beyond basic nutritional functions. This review will discuss the scientific literature on the effects and mechanisms by which functional food components influence metabolic control. Given the high and increasing incidence of glucose intolerance and Type 2 diabetes related to over-nutrition in Westernized societies and the potentially significant role of diet and food awareness in preventing or reversing this condition, this review will focus on those food components or supplements that specifically improve glycemic control...
May 23, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28543918/gut-microbiota-of-the-pine-weevil-degrades-conifer-diterpenes-and-increases-insect-fitness
#7
Aileen Berasategui, Hassan Salem, Christian Paetz, Maricel Santoro, Jonathan Gershenzon, Martin Kaltenpoth, Axel Schmdit
The pine weevil (Hylobius abietis), a major pest of conifer forests throughout Europe, feeds on the bark and cambium, tissues rich in terpenoid resins that are toxic to many insect herbivores. Here we report the ability of the pine weevil gut microbiota to degrade the diterpene acids of Norway spruce. The diterpene acid levels present in ingested bark were substantially reduced on passage through the pine weevil gut. This reduction was significantly less upon antibiotic treatment, and supplementing the diet with gut suspensions from untreated insects restored the ability to degrade diterpenes...
May 21, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28541810/effects-of-a-carbohydrate-glutamine-and-antioxidant-enriched-oral-nutrition-supplement-on-major-surgery-induced-insulin-resistance-a-randomized-pilot-study
#8
Mireille F M van Stijn, Maarten R Soeters, Paul A M van Leeuwen, W H Schreurs, Margreet G Schoorl, Jos W R Twisk, Jean-Pascal De Bandt, Dominique Bonnefont-Rousselot, Luc Cynober, Mariette T Ackermans, Mireille J Serlie, Alexander P J Houdijk
BACKGROUND: Insulin resistance after surgery hampers recovery. Oxidative stress is shown to be involved in the occurrence of postoperative insulin resistance. Preoperative carbohydrate-rich oral nutrition supplements reduce but do not prevent insulin resistance. The aim of the present study was to investigate the effect of a carbohydrate-, glutamine-, and antioxidant-enriched preoperative oral nutrition supplement on postoperative insulin resistance. METHODS: A double-blind randomized controlled pilot study in 18 patients with rectal cancer, who received either the supplement (S) or the placebo (P) 15, 11, and 4 hours preoperatively, was conducted...
May 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28541582/definition-of-a-tolerable-upper-intake-level-of-niacin-a-systematic-review-and-meta-analysis-of-the-dose-dependent-effects-of-nicotinamide-and-nicotinic-acid-supplementation
#9
Clara Minto, Maria Gabriella Vecchio, Manfred Lamprecht, Dario Gregori
Nicotinic acid and nicotinamide are soluble compounds of the vitamin B group, widely used to regulate the lipid profile in hyperlipidemic individuals. Higher doses of nicotinic acid are associated with adverse effects, especially flushing. A unique tolerable upper intake level (UL) of nicotinic acid has not been defined. This meta-analysis aims to evaluate adverse effects and their incidence after supplementation with different doses of nicotinic acid and nicotinamide, comparing results with current ULs in Europe and the United States...
May 25, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28541261/nutrient-enriched-infant-formula-is-associated-with-higher-weight-gain-for-low-birth-weight-infants
#10
Michelle Ngan, Ramon Durazo-Arvizu, Marc G Weiss, Holly Kramer
OBJECTIVE: Nutrient-enriched formulas were developed to provide extra nutrients and facilitate optimal growth for low birth weight infants. This study examined the association between use of nutrient-enriched formulas and weight gain among low birth weight infants (birth weight 1500-2500 g). METHODS: This retrospective cohort study used data from infants enrolled in the Illinois Special Supplemental Nutrition Program for Women, Infants, and Children. Analyses were limited to infants born in 2010 with low birth weight (1500-2500 g, n = 3130)...
June 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28539734/honey-and-health-a-review-of-recent-clinical-research
#11
REVIEW
Saeed Samarghandian, Tahereh Farkhondeh, Fariborz Samini
Honey is one of the most appreciated and valued natural products introduced to humankind since ancient times. Honey is used not only as a nutritional product but also in health described in traditional medicine and as an alternative treatment for clinical conditions ranging from wound healing to cancer treatment. The aim of this review is to emphasize the ability of honey and its multitude in medicinal aspects. Traditionally, honey is used in the treatment of eye diseases, bronchial asthma, throat infections, tuberculosis, thirst, hiccups, fatigue, dizziness, hepatitis, constipation, worm infestation, piles, eczema, healing of ulcers, and wounds and used as a nutritious supplement...
April 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/28539198/total-usual-intake-of-shortfall-nutrients-varies-with-poverty-among-us-adults
#12
Regan L Bailey, Sharon R Akabas, Erin E Paxson, Sowmyanarayanan V Thuppal, Shilpa Saklani, Katherine L Tucker
OBJECTIVE: To examine shortfall nutrient intakes (ie, calcium, folate, potassium, magnesium, and vitamins A, C, D, and E) by poverty-to-income ratio (PIR). DESIGN: National Health and Nutrition Examination Survey 2011-2012, a nationally representative, cross-sectional survey. PARTICIPANTS: US adults with complete data on poverty status and diet were included (n = 4,524). ANALYSIS: The National Cancer Institute method was used to estimate total usual micronutrient intakes from foods, beverages, medications, and dietary supplements reported on 2 24-hour dietary recalls using measurement error correction...
May 20, 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/28539168/effectiveness-of-nutritional-supplementation-on-sarcopenia-and-recovery-in-hip-fracture-patients-a-multi-centre-randomized-trial
#13
Vincenzo Malafarina, Francisco Uriz-Otano, Concetta Malafarina, J Alfredo Martinez, M Angeles Zulet
BACKGROUND AND OBJECTIVES: Functional deterioration and reduced mobility in elderly patients with a hip fracture are associated with a loss of both muscle mass and function (sarcopenia). The aim of this study was to assess whether oral nutritional supplementation (ONS) improves muscle mass and nutritional markers (BMI, proteins) in elderly patients with hip fracture. METHODS: Patients aged 65 years and over with hip fractures admitted to either of two rehabilitation facilities were included...
July 2017: Maturitas
https://www.readbyqxmd.com/read/28537863/severe-pellagra-masked-by-concurrent-plaque-psoriasis-a-case-report-of-a-hidden-diagnosis
#14
Elizabeth A Wang, Jason Kao, Michelle Y Cheng, Chelsea Ma, Soneet Dhillon, Thomas Konia, Emanual Maverakis, Cindy J Chambers
Despite characteristic features, psoriasis can mimic other dermatologic conditions, such as seborrheic dermatitis, lichen simplex chronicus, and certain nutritional deficiencies such as pellagra. We present a patient with a longstanding history of severe plaque psoriasis who presented with disfiguring scaly plaques involving greater than 80% body surface area. The patient's disease was minimally responsive to multiple therapies. Repeat punch biopsies demonstrated parakeratosis, psoriasiform hyperplasia, and dilated blood vessels consistent with psoriasis...
May 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28537583/impact-of-the-n-6-n-3-long-chain-pufa-ratio-during-pregnancy-and-lactation-on-offspring-neurodevelopment-5-year-follow-up-of-a-randomized-controlled-trial
#15
C Brei, L Stecher, S Brunner, R Ensenauer, F Heinen, P D Wagner, J Hermsdörfer, H Hauner
BACKGROUND/OBJECTIVES: Evidence regarding the effect of n-3 long-chain polyunsaturated fatty acid (LCPUFA) supplementation during pregnancy on offspring's neurodevelopment is not conclusive. SUBJECTS/METHODS: In this analysis, the effect of a reduced n-6:n-3 LCPUFA ratio in the diet of pregnant/lactating women (1.2 g n-3 LCPUFA together with an arachidonic acid (AA)-balanced diet between 15th wk of gestation-4 months postpartum vs control diet) on child neurodevelopment at 4 and 5 years of age was assessed...
May 24, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28537580/effects-of-supplementation-with-quercetin-on-plasma-c-reactive-protein-concentrations-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#16
REVIEW
M Mohammadi-Sartang, Z Mazloom, S Sherafatmanesh, M Ghorbani, Donya Firoozi
Promising experimental studies suggest that quercetin has potential anti-inflammatory effects. However, the results of current clinical trials on quercetin's effects on the C-reactive protein (CRP), a sensitive inflammatory biomarker, are ambiguous. We conducted a meta-analysis of available randomized controlled trials (RCTs) to resolve this inconsistency and quantify the net effect of quercetin on circulating CRP concentrations. A systematic search was performed in several databases including SCOPUS, PubMed-Medline and Google Scholar until 16 June 2016...
May 24, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28537329/efficacy-of-a-disease-specific-nutritional-support-for-pressure-ulcer-healing-a-systematic-review-and-meta-analysis
#17
E Cereda, J C L Neyens, R Caccialanza, M Rondanelli, J M G A Schols
OBJECTIVES: The aim of this systematic review was to summarize the evidence on the efficacy of high-calorie, high-protein nutritional formula enriched with arginine, zinc, and antioxidants (disease-specific support) in patients with pressure ulcers (PUs). METHODS: Randomized controlled trials in English published from January 1997 until October 2015 were searched for in electronic databases (EMBASE, Medline, PubMed, and CINAHL). Studies comparing a disease-specific nutritional support (oral supplements or tube feeding) to a control nutritional intervention enabling the satisfaction of energy requirements regardless of the use of high-calorie formula or placebo or no support for at least 4 weeks were considered eligible...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28537130/qualitative-assessment-of-key-messages-about-nutrition-and-weight-gain-in-pregnancy-in-printed-educational-materials-in-alberta
#18
Laura Forbes, Janis Baarda, Maria Mayan, Rhonda C Bell
Printed educational materials are a common source of health information, although their effectiveness in improving women's knowledge or self-care in pregnancy has been questioned. This study describes the information in printed educational materials that address healthy eating during pregnancy and gestational weight gain (GWG) that are currently used in Alberta, Canada. Content of 6 resources was analyzed using a constant comparison qualitative approach. Resources emphasized healthy eating, prenatal supplements, folate supplementation, and healthy weight gain...
May 24, 2017: Canadian Journal of Dietetic Practice and Research
https://www.readbyqxmd.com/read/28534028/mechanisms-affecting-the-gut-of-preterm-infants-in-enteral-feeding-trials
#19
Nicholas D Embleton, Janet E Berrington, Jon Dorling, Andrew K Ewer, Edmund Juszczak, John A Kirby, Christopher A Lamb, Clare V Lanyon, William McGuire, Christopher S Probert, Stephen P Rushton, Mark D Shirley, Christopher J Stewart, Stephen P Cummings
Large randomized controlled trials (RCTs) in preterm infants offer unique opportunities for mechanistic evaluation of the risk factors leading to serious diseases, as well as the actions of interventions designed to prevent them. Necrotizing enterocolitis (NEC) a serious inflammatory gut condition and late-onset sepsis (LOS) are common feeding and nutrition-related problems that may cause death or serious long-term morbidity and are key outcomes in two current UK National Institutes for Health Research (NIHR) trials...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/28534027/current-concepts-and-unresolved-questions-in-dietary-protein-requirements-and-supplements-in-adults
#20
REVIEW
Stuart M Phillips
Protein needs for otherwise healthy individuals older than 19 years are defined by the recommended dietary allowance (RDA) at 0.80 g protein/kg/day. There is no recommendation in the current RDA for subpopulations of older adults or people in various pathological situations. Despite the lack of a separate recommendation, there exists a growing body of evidence that is strongly suggestive of an increased need and/or benefit for protein in older persons. That is, intakes beyond the RDA are, in older persons, associated with benefits...
2017: Frontiers in Nutrition
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