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https://www.readbyqxmd.com/read/29771211/the-benefit-of-extending-oral-anticoagulation-treatment-excoa-after-acute-cerebral-vein-thrombosis-cvt-excoa-cvt-cluster-randomized-trial-protocol
#1
Bruno Miranda, Sanjith Aaron, Antonio Arauz, Fernando Barinagarrementeria, Afshin Borhani-Haghighi, Marta Carvalho, Adriana B Conforto, Jonathan M Coutinho, Jan Stam, Patrícia Canhão, José M Ferro
Rationale After a cerebral vein thrombosis, there is an increased risk of further venous thromboembolic events. The optimal duration of anticoagulation after cerebral vein thrombosis is unknown. Aim To compare efficacy and safety of a policy of short- (3-6 months) versus long-term (12 months) anticoagulation (any type venous thromboembolic events) after cerebral vein thrombosis for the prevention of venous thromboembolic events. Sample size estimates A sample of 1428 patients (749 per arm) allows detecting a reduction from 10 to 5% in the risk of venous thromboembolic event recurrence with 80% power at 5% significance, with 3% dropout rate...
January 1, 2018: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/29765565/the-rediscovery-of-the-social-side-of-medicine-philosophy-and-value-of-the-international-classification-of-functioning-disability-and-health-icf
#2
EDITORIAL
Wolfgang Seger
Medicine is at risk of sliding into a sole repair service for the malfunction of organs. But the patients' hope and confidence towards doctors practicing this repair work go far beyond that: after acute medical treatment many patients suffer from chronic impairments due to the natural course of the disease or as a result of medical interventions. Despite resulting handicaps, patients aim at participating in family and social life, retaining a workplace and receiving support to remain a valued member of the family and the community...
March 2018: Electronic Physician
https://www.readbyqxmd.com/read/29759806/integration-of-post-acute-care-and-hospice-care-in-adult-day-services
#3
Mary Beth Happ, Holly Dabelko-Schoeny, Jiwon Shin
No abstract text is available yet for this article.
May 11, 2018: Geriatric Nursing
https://www.readbyqxmd.com/read/29756498/construct-validity-and-inter-rater-reliability-of-the-dutch-activity-measure-for-post-acute-care-6-clicks-basic-mobility-form-to-assess-the-mobility-of-hospitalized-patients
#4
Sven Jacobus Gertruda Geelen, Karin Valkenet, Cindy Veenhof
To evaluate the construct validity and the inter-rater reliability of the Dutch Activity Measure for Post-Acute Care "6-clicks" Basic Mobility short form measuring the patient's mobility in Dutch hospital care. First, the "6-clicks" was translated by using a forward-backward translation protocol. Next, 64 patients were assessed by the physiotherapist to determine the validity while being admitted to the Internal Medicine wards of a university medical center. Six hypotheses were tested regarding the construct "mobility" which showed that: Better "6-clicks" scores were related to less restrictive pre-admission living situations (p = 0...
May 12, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29755348/the-fibrin-cleavage-product-b%C3%AE-15-42-channels-endothelial-and-tubular-regeneration-in-the-post-acute-course-during-murine-renal-ischemia-reperfusion-injury
#5
Dania Fischer, Christopher Seifen, Patrick Baer, Michaela Jung, Christina Mertens, Bertram Scheller, Kai Zacharowski, Rainer Hofmann, Thorsten J Maier, Anja Urbschat
Early and adequate restoration of endothelial and tubular renal function is a substantial step during regeneration after ischemia reperfusion (IR) injury, occurring, e.g., in kidney transplantation, renal surgery, and sepsis. While tubular epithelial cell injury has long been of central importance, recent perception includes the renal vascular endothelium. In this regard, the fibrin cleavage product fibrinopeptide Bβ15-42 mitigate IR injury by stabilizing interendothelial junctions through its affinity to VE-cadherin...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29754125/projected-real-world-effectiveness-of-using-aggressive-low-density-lipoprotein-cholesterol-targets-among-elderly-statin-users-following-acute-coronary-syndromes-in-canada
#6
David A Alter, Jack V Tu, Maria Koh, Cynthia A Jackevicius, Peter C Austin, Mohammad R Rezai, R Sacha Bhatia, Sharon Johnston, Jacob A Udell, Dennis T Ko
BACKGROUND: The extent to which outcome benefits may be achieved through the implementation of aggressive low-density lipoprotein (LDL) cholesterol targets in real world settings remains unknown, especially among elderly statin users following acute coronary syndromes. METHODS AND RESULTS: A population-based cohort study consisting of 19 544 post-acute coronary syndrome statin-users aged ≥66 years between January 1, 2017 and March 31, 2014 was used to project the number of adverse outcome events (acute myocardial infarction or death from any cause) that could be prevented if all post-acute coronary syndrome elderly statin users were treated to 1 of 2 LDL cholesterol target levels (≤50 and ≤70 mg/dL)...
May 12, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29748911/patient-education-and-rehabilitation-after-hip-arthroplasty-in-an-italian-spa-center-a-pilot-study-on-its-feasibility
#7
Alfredo Musumeci, Giulia Pranovi, Stefano Masiero
Nowadays, some spa centers are suitable for providing rehabilitative and preventive treatment in association with traditional spa therapy. This study aims to evaluate the feasibility and the effectiveness of an intensive rehabilitation program after hip arthroplasty in an Italian spa center. Early after total hip arthroplasty for severe osteoarthritis (≤ 10 days after the intervention), 12 consecutive patients (5 males and 7 females) aged between 50 and 85 years were enrolled for this study. All the patients performed a 2-week thermal multimodal rehabilitation program, which consisted of education and physical rehabilitative measures...
May 11, 2018: International Journal of Biometeorology
https://www.readbyqxmd.com/read/29748087/trends-in-hospital-snf-relationships-in-the-care-of-medicare-beneficiaries
#8
Joshua M Liao, R Tamara Konetzka, Rachel M Werner
Improving the value of post-acute care at skilled nursing facilities (SNFs) has become a Medicare policy priority. Anecdotally, hospitals have responded by formally acquiring or pursuing tighter informal connections with SNFs. We evaluated the trend in connections between US acute care hospitals and Medicare-certified SNFs between 2000 and 2013 using vertical integration and two novel network-based measures (number of SNF partners, and discharge concentration). Among 4441 hospitals and 17,215 SNFs, hospitals with weaker connections with SNFs were more often non-profit, major teaching hospitals with a larger number of discharges and beds...
May 7, 2018: Healthcare
https://www.readbyqxmd.com/read/29738278/functional-outcomes-following-post-acute-rehabilitation-for-moderate-to-severe-traumatic-brain-injury
#9
Amy M Rosenbaum, Wayne A Gordon, Antigone Joannou, Brady A Berman
OBJECTIVE: The objective of this study was to examine the benefits of long-term inpatient rehabilitation for individuals with moderate-to-severe traumatic brain injuries (TBIs). METHODS: Retrospective database review of 67 individuals with moderate-to-severe TBI admitted to a specialised inpatient TBI program. Outcome measures are as follows: (1) functional independence measure + functional assessment measure (FIM+FAM; admission, discharge, change scores); (2) discharge designation (community vs...
May 8, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29712605/long-term-functional-outcomes-after-blunt-cerebrovascular-injury-a-20-year-experience
#10
Charles P Shahan, Taylor C Stavely, Martin A Croce, Timothy C Fabian, Louis J Magnotti
Since blunt cerebrovascular injury (BCVI) became increasingly recognized more than 20 years ago, significant improvements have been made in both diagnosis and treatment. Little is known regarding long-term functional outcomes in BCVI. The purpose of this study was to evaluate the impact of BCVI on those long-term outcomes. All patients with BCVI from 1996 to 2014 were identified from the trauma registry. Functional outcome was measured using the Boston University Activity Measure for Post-Acute Care. Multiple regression analysis was performed to identify potential predictors of outcomes...
April 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29704475/chronic-cough-related-to-acute-viral-bronchiolitis-in-children-chest-expert-panel-report
#11
Anne B Chang, John J Oppenheimer, Bruce K Rubin, Miles Weinberger, Richard S Irwin
BACKGROUND: Acute bronchiolitis is common in young children and some children develop chronic cough after their bronchiolitis. We thus undertook systematic reviews based on key questions (KQs) using the PICO format. The KQs were: Among children with chronic cough (>4 weeks) after acute viral bronchiolitis, how effective are the following interventions in improving the resolution of cough?: (1) Antibiotics. If so what type and for how long? (2) Asthma medications (inhaled steroids, beta2 agonist, montelukast) and; (3) Inhaled osmotic agents like hypertonic saline? METHODS: We used the CHEST expert cough panel's protocol and the American College of Chest Physicians (CHEST) methodological guidelines and GRADE framework...
April 25, 2018: Chest
https://www.readbyqxmd.com/read/29703444/regional-disparities-in-acute-and-post-acute-care-of-stroke-patients-in-france-2015
#12
C de Peretti, A Gabet, C Lecoffre, P Oberlin, Valérie Olié, F Woimant
OBJECTIVE: The aim of this study was to assess regional variations of the hospital management of stroke patients during acute and post-acute phases in France in 2015. MATERIAL AND METHODS: Hospitalized patients coded with stroke as their main diagnosis or, if hospitalized in several different wards, any main ward diagnosis were identified in the 2015 French national hospital discharge database for acute care. Rates of hospitalization in stroke units (SUs) were assessed at a national level and in all metropolitan and overseas regions...
April 24, 2018: Revue Neurologique
https://www.readbyqxmd.com/read/29703085/significance-of-asymptomatic-hyperuricemia-in-patients-after-coronary-events
#13
Ivan Tasić, Svetlana Kostić, Nikola M Stojanović, Vlado Skakić, Jovana Cvetković, Aleksandar Djordjević, Mirjana Karadzić, Dragan Djordjević, Stanoje Andonov, Viktor Stoičkov, Dimitrije Tasić, Meenakshi Vanka, Dragan Lović
The goal of the present study was to determine the prevalence of hyperuricemia in patients with coronary artery disease (CAD), within three months after coronary events. Also, we aimed to determine whether the presence of hyperuricemia holds correlation with severe CAD, overall heart functioning and risk factors for CAD. The study included 505 consecutive CAD patients, 385 males and 120 females, aged 60.9 ± 9.6 years, with a mean body mass index (BMI) 28.0 ± 3.7 kg/m2 . All patients were admitted to specialized cardiovascular rehabilitation within three months post-acute myocardial infarction (AMI) without revascularization (32...
April 27, 2018: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/29697778/quality-of-post-acute-care-in-skilled-nursing-facilities-that-disproportionately-serve-black-and-hispanic-patients
#14
Maricruz Rivera-Hernandez, Momotazur Rahman, Dana B Mukamel, Vincent Mor, Amal N Trivedi
Background: Understanding and addressing racial and ethnic disparities in the quality of post-acute care in skilled nursing facilities is an important health policy issue, particularly as the Medicare program initiates value-based payments for these institutions. Methods: Our final cohort included 649,187 Medicare beneficiaries in either the fee-for-service or Medicare Advantage programs, who were 65 and older and were admitted to a skilled nursing facility following an acute hospital stay, from 8,375 skilled nursing facilities...
April 25, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29696357/stigma-experiences-and-perceived-stigma-in-patients-with-first-episode-schizophrenia-in-the-course-of-1-year-after-their-first-in-patient-treatment
#15
Harald Zäske, Michael Linden, Detlef Degner, Maria Jockers-Scherübl, Stefan Klingberg, Joachim Klosterkötter, Wolfgang Maier, Hans-Jürgen Möller, Heinrich Sauer, Andrea Schmitt, Wolfgang Gaebel
Patients with schizophrenia suffer from stigma and discrimination due to their illness. Yet it is not well examined how experiences of stigma and discrimination express at the early illness stage and how they develop subsequently. Therefore, clinical and psycho-social correlates of stigma experiences and perceived stigma are analyzed in patients with first-episode schizophrenia over the course of 1 year after their first in-patient treatment. Questionnaire data assessed within the multi-centre-RCT "First-Episode Study" of the German Research Network on Schizophrenia were analyzed...
April 25, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29691152/readmission-patterns-over-90-day-episodes-of-care-among-medicare-fee-for-service-beneficiaries-discharged-to-post-acute-care
#16
Addie Middleton, Yong-Fang Kuo, James E Graham, Amol Karmarkar, Yu-Li Lin, James S Goodwin, Allen Haas, Kenneth J Ottenbacher
OBJECTIVE: Examine readmission patterns over 90-day episodes of care in persons discharged from hospitals to post-acute settings. DESIGN: Retrospective cohort study. SETTING: Acute care hospitals. PARTICIPANTS: Medicare fee-for-service enrollees (N = 686,877) discharged from hospitals to post-acute care in 2013-2014. The cohort included beneficiaries >65 years of age hospitalized for stroke, joint replacement, or hip fracture and who survived for 90 days following discharge...
April 21, 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29683734/six-year-review-of-traumatic-brain-injury-in-a-regional-trauma-unit-demographics-contributing-factors-and-service-provision-in-ireland
#17
Patrick W Owens, Noel P Lynch, Donal P O'Leary, Aoife J Lowery, Michael J Kerin
BACKGROUND: Traumatic brain injury (TBI) represents a significant burden of care for acute surgical services, particularly in the absence of on-site neurosurgical cover or sufficient post-acute rehabilitation facilities. We examine factors contributing to TBI, prolonged lengths of stay (LoS) and implications for hospital resources. Long-term outcomes are assessed. METHODS: This is a retrospective cohort study of patients admitted to a regional trauma unit with TBI from 2008 to 2013...
April 23, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29677292/trends-in-post-acute-care-use-among-medicare-beneficiaries-2000-to-2015
#18
Rachel M Werner, R Tamara Konetzka
No abstract text is available yet for this article.
April 17, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29671614/metabolic-syndrome-and-diabetes-in-post-acute-myocardial-infarction-patients
#19
Susana Sans
No abstract text is available yet for this article.
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29667144/efficacy-and-safety-of-zofenopril-versus-ramipril-in-the-treatment-of-myocardial-infarction-and-heart-failure-a-review-of-the-published-and-unpublished-data-of-the-randomized-double-blind-smile-4-study
#20
REVIEW
Claudio Borghi, Stefano Omboni, Salvatore Novo, Dragos Vinereanu, Giuseppe Ambrosio, Ettore Ambrosioni
Zofenopril is a lipophilic, sulfhydryl group-containing angiotensin-converting enzyme (ACE)-inhibitor, characterized by wide tissue distribution, long duration of action, and pleiotropic effects on endothelial dysfunction. Its clinical efficacy and safety have been described in the four randomized controlled trials of the SMILE program, which globally enrolled more than 3600 patients in post-acute myocardial infarction (AMI) setting. The SMILE-4 study specifically selected patients with left ventricular dysfunction at admission, and compared the effects of zofenopril or ramipril in combination with acetylsalicylic acid (ASA)...
April 17, 2018: Advances in Therapy
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