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https://www.readbyqxmd.com/read/28719872/health-related-quality-of-life-in-patients-undergoing-lumbar-total-disc-replacement-a-comparison-with-the-general-population
#1
Clavel Pablo, Gheorghe Ungureanu, Catalá Ignasi, Guillermo Montes, Xavier Málaga, Moisés Ríos
OBJECTIVES: In up to half of the cases, low back pain (LBP) is thought to be related to a degeneration of the lumbar disc. Lumbar total disc replacement (LTDR) emerged as an alternative to fusion, but its use and indications are still subject to debate. The purpose of this paper was to compare Health-related Quality of life (HRQOL) in patients undergoing LTDR for one or two-level degenerative disc disease (DDD) with the paired age and gender general population values and to assess functional disability and residual pain at one year after the surgical procedure...
July 11, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28718810/dna2-an-important-player-in-dna-damage-response-or-just-another-dna-maintenance-protein
#2
REVIEW
Elzbieta Pawłowska, Joanna Szczepanska, Janusz Blasiak
The human DNA2 (DNA replication helicase/nuclease 2) protein is expressed in both the nucleus and mitochondria, where it displays ATPase-dependent nuclease and helicase activities. DNA2 plays an important role in the removing of long flaps in DNA replication and long-patch base excision repair (LP-BER), interacting with the replication protein A (RPA) and the flap endonuclease 1 (FEN1). DNA2 can promote the restart of arrested replication fork along with Werner syndrome ATP-dependent helicase (WRN) and Bloom syndrome protein (BLM)...
July 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28717794/the-influence-of-maxillary-incisor-torque-on-the-esthetic-perception-%C3%A2-of-the-smile
#3
Javier Giron de Velasco, Pablo de la Cuadra, Gorka Urizar
PURPOSE: An esthetically pleasing smile is one of our patients' main goals. However, it is not always clear that the esthetic perceptions of patients and clinicians are the same. The purpose of this study was to evaluate and quantify the discrepancies in the esthetic perception of maxillary incisor torque among professionals, and between professionals and the general public. MATERIALS AND METHODS: A photograph of a 30-year-old woman was digitally manipulated to obtain nine smile images and nine full-profile images with various maxillary incisor torques, while maintaining the overjet...
2017: International Journal of Esthetic Dentistry
https://www.readbyqxmd.com/read/28715436/use-of-water-turnover-method-to-measure-mother-s-milk-flow-in-a-rat-model-application-to-dams-receiving-a-low-protein-diet-during-gestation-and-lactation
#4
Thomas Sevrin, Marie-Cécile Alexandre-Gouabau, Dominique Darmaun, Antoine Palvadeau, Agnès André, Patrick Nguyen, Khadija Ouguerram, Clair-Yves Boquien
Assessment of milk production is of utmost relevance for pediatricians and scientists interested in early life nutrition. The weight-suckle-weight (WSW) method, which consists of weighing babies before and after they suckle their mother, uses the difference in body weight as an estimate of milk intake. However, this is prone to many sources of error. In the current study, we used for the first time the water turnover method and compartmental analysis with deuterated water (D2O) as a non-toxic tracer to quantify in vivo milk production in a rat model...
2017: PloS One
https://www.readbyqxmd.com/read/28714886/non-convex-sparse-and-low-rank-based-robust-subspace-segmentation-for-data-mining
#5
Wenlong Cheng, Mingbo Zhao, Naixue Xiong, Kwok Tai Chui
Parsimony, including sparsity and low-rank, has shown great importance for data mining in social networks, particularly in tasks such as segmentation and recognition. Traditionally, such modeling approaches rely on an iterative algorithm that minimizes an objective function with convex l₁-norm or nuclear norm constraints. However, the obtained results by convex optimization are usually suboptimal to solutions of original sparse or low-rank problems. In this paper, a novel robust subspace segmentation algorithm has been proposed by integrating lp-norm and Schatten p-norm constraints...
July 15, 2017: Sensors
https://www.readbyqxmd.com/read/28713635/fibrous-encapsulation-of-the-peritoneal-catheter-in-peritoneal-shunt-case-report
#6
Tomoaki Kano, Hideyuki Kawauchi
BACKGROUND: The authors report a case of fibrous encapsulation of the peritoneal catheter, which caused peritoneal shunt malfunction, and has not previously been researched well as a complication of peritoneal shunts. CASE DESCRIPTION: A 69-year-old woman who had undergone a lumboperitoneal (LP) shunt for communicative hydrocephalus following subarachnoid hemorrhage caused by a ruptured aneurysm was identified with malfunction of the LP shunt system by dementia and gait disturbance...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28712188/a-novel-link-between-adipokines-and-lipoprotein-a-to-contemplate-their-diagnostic-role-in-patients-with-stemi-and-nstemi
#7
Shazia Rashid, Rukhshan Khurshid, Uzma Faryal Amir, Arif Malik, Sumera Qazi
BACKGROUND: Early detection of cardiac events allow better and cost-effective triage and welltimed management of these patients. Study was conducted to evaluate the prognostic significance of plasma adiponectin, resistin and lipoprotein (a) in a group of patients with ST segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction. These parameters were also compared with other predictors like troponin T, troponin I and CK-MB. METHODS: Present study was based on the 100 patients with AMI of whom 52 had a diagnosis of STEMI, and 48 had NSTEMI...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28711708/ezetimibe-and-simvastatin-combination-inhibits-and-reverses-the-pro-inflammatory-and-pro-atherogenic-effects-of-cream-in-obese-patients
#8
Husam Ghanim, Kelly Green, Sanaa Abuaysheh, Reema Patel, Manav Batra, Ajay Chaudhuri, Antoine Makdissi, Nitesh D Kuhadiya, Paresh Dandona
BACKGROUND AND AIMS: Inflammation and postprandial lipemia are associated with increased cardiovascular disease. We investigated whether ezetimibe and simvastatin combination, a lipid lowering combination of simvastatin and ezetimibe, exerts an anti-inflammatory effect in the fasting state and after dairy cream intake. METHODS: Twenty obese patients were randomized to either ezetimibe and simvastatin combination or placebo treatment for 6 weeks. All patients were asked to ingest 33 ml of dairy cream (300 Calories) at the beginning and at the end of intervention...
June 7, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28711253/the-capacity-of-silage-inoculant-bacteria-to-bind-aflatoxin-b1-in-vitro-and-in-artificially-contaminated-corn-silage
#9
Z X Ma, F X Amaro, J J Romero, O G Pereira, K C Jeong, A T Adesogan
The objectives were to examine the aflatoxin B1 (AFB1)-binding capacity of silage bacteria and factors affecting the responses. Experiments 1 and 2 examined the effects of bacterial strain and population on the AFB1-binding capacity of 10 bacteria. When applied at 10(6) cfu/mL to an in vitro medium, only Lactobacillus plantarum PT5B bound the AFB1 and the binding capacity was low (4%). When applied at 10(9) cfu/mL, all 10 bacteria bound AFB1, but L. plantarum R2014 (Lp) and EQ12, Lactobacillus buchneri R1102 (Lb), and Pediococcus acidilactici R2142 and EQ01 (Pa) had the greatest capacity (23...
July 12, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28711218/significant-axial-elongation-with-minimal-change-in-refraction-in-3-to-6-year-old-chinese-preschoolers-the-shenzhen-kindergarten-eye-study
#10
Xinxing Guo, Min Fu, Xiaohu Ding, Ian G Morgan, Yangfa Zeng, Mingguang He
PURPOSE: To document the distribution of ocular biometry and to evaluate its associations with refraction in a group of Chinese preschoolers. DESIGN: Population-based cross-sectional study. PARTICIPANTS: A total of 1133 preschoolers 3 to 6 years of age from 8 representative kindergartens. METHODS: Biometric measurements including axial length (AL), anterior chamber depth (ACD), and corneal radius of curvature (CR) were obtained from partial-coherence laser interferometry (IOL Master; Carl Zeiss Meditec, Oberkochen, Germany) before cycloplegia...
July 13, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28709944/latex-proteins-from-calotropis-procera-toxicity-and-immunological-tolerance-revisited
#11
Camila F Bezerra, Érika F Mota, Ana Claudia M Silva, Adriana R Tomé, Maria Z R Silva, Daniel de Brito, Camila T M N Porfírio, Ariclécio C Oliveira, José V Lima-Filho, Márcio V Ramos
Many thousands of plants are disseminated worldwide in traditional and folk medicines based on the belief that their leaves, roots, seeds, bark or secretions, when adequately handled, can treat, alleviate or ameliorate numerous disease symptoms. Calotropis procera (Apocynaceae) is a popular medicinal plant and the claims of this shrub's phytomedicinal properties have been scientifically validated. In this study, further prospects towards the in vivo toxicity and oral immunological tolerance of phytomodulatory proteins isolated from the latex of C...
July 11, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28708531/relationships-among-early-postpartum-luteal-activity-parity-and-insemination-outcomes-based-on-in-line-milk-progesterone-profiles-in-canadian-holstein-cows
#12
Tony C Bruinjé, Marcos G Colazo, Mohanathas Gobikrushanth, Divakar J Ambrose
The objectives of this retrospective study were to use in-line milk progesterone (mP4) data to investigate relationships of (1) commencement of luteal activity (CLA), and (2) luteal phase (LP) length and frequency preceding first postpartum AI, with parity and AI outcomes in Canadian Holstein cows. Starting 21 ± 1 days postpartum (DPP), levels of mP4 were assessed every 2.2 ± 2.0 d through an automated in-line milk analysis system (Herd Navigator™, DeLaval International, Tumba, Sweden) until ∼55 d after first or second AI in 748 Holstein cows from two herds...
May 27, 2017: Theriogenology
https://www.readbyqxmd.com/read/28708225/clinical-outcomes-of-salvage-chemoradiotherapy-for-locally-recurrent-biliary-tract-cancer
#13
Jeong Il Yu, Hee Chul Park, Do Hoon Lim, Joon Oh Park, Young Suk Park, Seung Tae Kim, Seong Ho Choi, Dong Wook Choi, In Woong Han, Jin Seok Heo
PURPOSE: The purpose of this study was to investigate the clinical outcomes and prognostic factors of concurrent chemoradiotherapy (CCRT) for locally recurrent biliary tract cancer (BTC) after curative surgical resection. METHODS: We performed a retrospective cohort study of patients with locally recurrent BTC treated with CCRT between October 2004 and December 2013. The study included and analyzed 42 patients with a history of curative-intent surgical resection of confirmed adenocarcinoma originating from the biliary tract...
July 11, 2017: Tumori
https://www.readbyqxmd.com/read/28707531/third-version-of-vendor-specific-model-based-iterative-reconstruction-veo-3-0-evaluation-of-ct-image-quality-in-the-abdomen-using-new-noise-reduction-presets-and-varied-slice-optimization
#14
Morgan E Telesmanich, Corey T Jensen, Jose L Enriquez, Nicolaus A Wagner-Bartak, Xinming Liu, Ott Le, Wei Wei, Adam G Chandler, Eric P Tamm
OBJECTIVE: To qualitatively and quantitatively compare abdominal CT images reconstructed with a new version of model-based iterative reconstruction (Veo 3.0; GE Healthcare) utilizing varied presets of resolution preference, noise reduction, and slice optimization. METHODS: This retrospective study was approved by our IRB and was HIPAA compliant. The raw data from 30 consecutive patients who had undergone CT abdomen scanning were used to reconstruct 4 clinical presets of 3...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28706407/incidence-of-oral-lichen-planus-in-perimenopausal-women-a-cross-sectional-study-in-western-uttar-pradesh-population
#15
Ravi Prakash Sasankoti Mohan, Akanksha Gupta, Nagaraju Kamarthi, Sangeeta Malik, Sumit Goel, Swati Gupta
BACKGROUND: Hormonal fluctuations during menopause lead to endocrine changes in women, especially in their sex steroid hormone production. Studies have documented the role of estrogen and progesterone (Pg) on autoimmune disorders such as multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis. Lichen planus (LP), an autoimmune disorder, seen frequently in perimenopausal women, may also get affected by sex steroid hormones, but no direct relationship has been established yet...
April 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28705736/a-worldwide-experience-of-the-management-of-battery-failures-and-chronic-device-retrieval-of-the-nanostim-leadless-pacemaker
#16
Dhanunjaya Lakkireddy, Reinoud Knops, Brett Atwater, Petr Neuzil, John Ip, Elkin Gonzalez, Paul Friedman, Pascal Defaye, Derek Exner, Kazutaka Aonuma, Rahul Doshi, Johannes Sperzel, Vivek Reddy
BACKGROUND: The Nanostim leadless pacemaker (LP) met the primary endpoints in an IDE trial, and was shown to be fully retrievable percutaneously. In October 2016, St Jude Medical, issued a worldwide alert of a battery malfunction that caused lost pacing output and LP communication. OBJECTIVE: The objective here is to report the battery failure mechanism and incidence and the worldwide patient management including device retrieval experiences. METHODS: The affected LP battery is a custom Lithium-Carbon Monofluoride (Li-CFx) cell...
July 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28704853/rbp4-lp-pla2-netrin-1-signaling-regulation-of-cognitive-dysfunction-in-diabetic-nephropathy-complicated-with-silent-cerebral-infarction
#17
Danyan Chen, Xiaolong Huang, Song Lu, Huacong Deng, Hua Gan, Xiaogang Du, Tang Weixue
Aim To investigate the RBP4/Lp-PLA2/Netrin-1 signal regulation of cognitive function impairment in diabetic nephropathy patients with silent cerebral infarction (SCI). Methods One-hundred patients newly diagnosed with diabetic nephropathy patients were included. The patients were divided into SCI group and NSCI group according to the radiological data. The degrees of cognitive dysfunction were evaluated. Serum RBP4 concentrations were determined by ELISA and protein expressions of Lp-PLA2 and Netrin-1 were determined by Western Blot...
July 13, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28704465/lipoprotein-a-in-patients-with-aortic-stenosis-insights-from-cardiovascular-magnetic-resonance
#18
Vassilios S Vassiliou, Paul D Flynn, Claire E Raphael, Simon Newsome, Tina Khan, Aamir Ali, Brian Halliday, Annina Studer Bruengger, Tamir Malley, Pranev Sharma, Subothini Selvendran, Nikhil Aggarwal, Anita Sri, Helen Berry, Jackie Donovan, Willis Lam, Dominique Auger, Stuart A Cook, Dudley J Pennell, Sanjay K Prasad
BACKGROUND: Aortic stenosis is the most common age-related valvular pathology. Patients with aortic stenosis and myocardial fibrosis have worse outcome but the underlying mechanism is unclear. Lipoprotein(a) is associated with adverse cardiovascular risk and is elevated in patients with aortic stenosis. Although mechanistic pathways could link Lipoprotein(a) with myocardial fibrosis, whether the two are related has not been previously explored. In this study, we investigated whether elevated Lipoprotein(a) was associated with the presence of myocardial replacement fibrosis...
2017: PloS One
https://www.readbyqxmd.com/read/28701998/thyroid-autoimmunity-and-lichen
#19
REVIEW
Fabrizio Guarneri, Roberta Giuffrida, Flavia Di Bari, Serafinella Patrizia Cannavò, Salvatore Benvenga
Lichen planus (LP) and lichen sclerosus (LS) are cutaneous-mucous diseases with uncertain epidemiology. Current data, which are likely to be underestimated, suggest a prevalence in the general population of 0.1-4% for cutaneous LP, 1.27-2.0% for oral LP, and 0.1-3.3% for LS. While etiology of lichen is still unknown, clinical and histological evidence show an (auto)immune pathogenesis. Association of lichen with autoimmune thyroid disease (AITD) has been investigated in few studies. This association appears better defined in the case of LS, while is more controversial for LP...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28700032/lipoprotein-a-as-a-predictor-of-poor-collateral-circulation-in-patients-with-chronic-stable-coronary-heart-disease
#20
Y Fan, J-S Hu, F Guo, Z-B Lu, H Xia
As a mechanism compensating for obstructive coronary artery disease, coronary collateral circulation (CCC) has attracted cardiologists for a long time to explore its potential impact. In the present study, Chinese patients suffering from ≥95% coronary stenosis, as diagnosed by angiography, have been investigated for the correlation between CCC and lipoprotein(a) [Lp(a)] levels. A cohort of 654 patients was divided into four categories according to Rentrop grades 0, 1, 2, and 3. Lp(a) levels were divided into model 1, discretized with critical values of 33 and 66%, and model 2, discretized with a cutoff value of 30...
July 10, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
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