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https://www.readbyqxmd.com/read/28339861/constitutive-luteinizing-hormone-receptor-signaling-causes-sexual-dysfunction-and-leydig-cell-adenomas-in-male-mice1
#1
Lan Hai, Deepak S Hiremath, Marilène Paquet, Prema Narayan
The luteinizing hormone receptor (LHCGR) is necessary for fertility and genetic mutations cause defects in reproductive development and function. Activating mutations in LHCGR cause familial male limited precocious puberty (FMPP). We have previously characterized a mouse model (KiLHRD582G) for FMPP that exhibits the same phenotype of precocious puberty, Leydig cell hyperplasia and elevated testosterone as boys with the disorder. We observed that KiLHRD582G male mice became infertile by 6 months of age although sperm count and motility were normal...
February 17, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28333818/practice-bulletin-no-176-pelvic-organ-prolapse
#2
(no author information available yet)
Pelvic organ prolapse (POP) is a common, benign condition in women. For many women it can cause vaginal bulge and pressure, voiding dysfunction, defecatory dysfunction, and sexual dysfunction, which may adversely affect quality of life. Women in the United States have a 13% lifetime risk of undergoing surgery for POP (). Although POP can occur in younger women, the peak incidence of POP symptoms is in women aged 70-79 years (). Given the aging population in the United States, it is anticipated that by 2050 the number of women experiencing POP will increase by approximately 50% ()...
April 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28333810/practice-bulletin-no-176-summary-pelvic-organ-prolapse
#3
(no author information available yet)
Pelvic organ prolapse (POP) is a common, benign condition in women. For many women it can cause vaginal bulge and pressure, voiding dysfunction, defecatory dysfunction, and sexual dysfunction, which may adversely affect quality of life. Women in the United States have a 13% lifetime risk of undergoing surgery for POP (1). Although POP can occur in younger women, the peak incidence of POP symptoms is in women aged 70-79 years (2). Given the aging population in the United States, it is anticipated that by 2050 the number of women experiencing POP will increase by approximately 50% (3)...
April 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28332171/sport-and-male-sexuality
#4
REVIEW
P Sgrò, L Di Luigi
The relationships between sport and sexuality in males are of great social and clinical interest, because of sports and motor activities that highly promote social and sexual relationships. Even if few literature exist, two main questions should be taken into account: whether and how physical exercise and sport positively or negatively influence sexual health and behavior and/or whether and how sexual behavior may affect a sub-sequent sport performance. Physical exercise and sport per se can influence, positively or negatively, the hypothalamic-pituitary-testicular axis function and, consequently, the individual's reproductive and/or sexual health...
March 22, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28331743/psychiatric-symptoms-and-psychosocial-problems-in-patients-with-breast-cancer
#5
REVIEW
Filiz İzci, Ahmet Serkan İlgün, Ebru Fındıklı, Vahit Özmen
Cancer is a physical disease and also one of the leading clinical manifestations where psychosocial problems are prevalent. Psychosocial problems that these patients may have in the long run include anxiety, uneasiness, mourning, helplessness, fatigue, impairment of concentration, sleep disorders, mental and cognitive reservation, sexual dysfunction, infertility, psychological distress, and psychiatric disorders. Psychosocial problems have a nature of underpinning the emergence of psychological troubles. The prevalence of psychological disorders in patients with cancer range from 29% to 47%...
July 2016: J Breast Health (2013)
https://www.readbyqxmd.com/read/28330974/urinary-incontinence-and-sexual-dysfunction-are-worse-after-surgery-for-prostate-cancer-study-finds
#6
Jacqui Wise
No abstract text is available yet for this article.
March 21, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28330675/what-does-electromyography-tell-us-about-dyspareunia
#7
REVIEW
Linda McLean, Kaylee Brooks
INTRODUCTION: Emergent evidence suggests that pelvic floor muscle (PFM) dysfunction contributes to dyspareunia, the experience of pain on vaginal penetration. Electromyography (EMG) is a valuable tool for the assessment of neuromuscular control and could be very useful in enhancing our understanding of PFM involvement in sexual function and in conditions such as dyspareunia. However, PFM EMG must be interpreted within the context of the many factors that can influence findings. AIM: To outline the main factors to consider when evaluating PFM EMG for female sexual function and dyspareunia and to synthesize the literature in which EMG has been acquired and interpreted appropriately in this context...
March 18, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28328282/frequency-of-erectile-dysfunction-in-males-with-central-serous-chorioretinopathy
#8
Ayse Balkarli, Muhammet Kazim Erol, Soner Yalcinkaya, Rumeysa Selvinaz Erol
OBJECTIVES: To evaluate the frequency of sexual dysfunction and associated factors in patients with central serous chorioretinopathy (CSCR). MATERIAL AND METHODS: Fifty-eight CSCR patients who met the inclusion criteria and 99 age- and sex-matched healthy controls were prospectively investigated for sexual dysfunction and associated factors. All participants were investigated using the Beck Depression Inventory (BDI), Beck Anxiety Scale (BAS), and the15-question Index of Erectile Function-15 (IIEF-15) and by extensive examination of CSCR, associated factors, and confounding factors...
March 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28324092/association-between-choice-of-radical-prostatectomy-external-beam-radiotherapy-brachytherapy-or-active-surveillance-and-patient-reported-quality-of-life-among-men-with-localized-prostate-cancer
#9
Ronald C Chen, Ramsankar Basak, Anne-Marie Meyer, Tzy-Mey Kuo, William R Carpenter, Robert P Agans, James R Broughman, Bryce B Reeve, Matthew E Nielsen, Deborah S Usinger, Kiayni C Spearman, Sarah Walden, Dianne Kaleel, Mary Anderson, Til Stürmer, Paul A Godley
Importance: Patients diagnosed with localized prostate cancer have to decide among treatment strategies that may differ in their likelihood of adverse effects. Objective: To compare quality of life (QOL) after radical prostatectomy, external beam radiotherapy, and brachytherapy vs active surveillance. Design, Setting, and Participants: Population-based prospective cohort of 1141 men (57% participation among eligible men) with newly diagnosed prostate cancer were enrolled from January 2011 through June 2013 in collaboration with the North Carolina Central Cancer Registry...
March 21, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28323519/improvement-of-low-sexual-desire-due-to-antiandrogenic-combined-oral-contraceptives-after-switching-to-an-oral-contraceptive-containing-17%C3%AE-estradiol
#10
Salvatore Caruso, Stefano Cianci, Maria Cariola, Valentina Fava, Salvatore Di Pasqua, Antonio Cianci
OBJECTIVES: To investigate the effects of a combined oral contraceptive (COC) containing 17β-estradiol (E2) 1.5 mg and nomegestrol acetate 2.5 mg (NOMAC/E2) on the sexual health of women affected by low sexual desire due to COCs containing ethinylestradiol. MATERIALS AND METHODS: Eighty-three women (age range 19-32) participated in the study. Sex hormone-binding globulin (SHBG), total testosterone (TT), and free androgen index (FAI) were measured. The Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale (FSDS) questionnaires were used to assess sexual function and distress, respectively...
March 21, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28321467/-sexual-dysfunction-associated-with-psychotropic-drugs-and-treatment-options
#11
M Berner
BACKGROUND: Sexual dysfunction associated with psychotropic drugs is a threat to patient quality of life and a major reason for non-compliance. Psychotropic agents can impair the sexual response in different ways due to their neurobiological mode of action. OBJECTIVE: Presentation of the frequencies of sexual functional disorders for selected psychopharmacological groups and the available treatment modalities. METHODS: Literature search, selection and review of relevant studies...
March 20, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28319007/sexual-dysfunctions-in-diabetes-a-gender-issue
#12
Maria Ida Maiorino, Giuseppe Bellastella, Katherine Esposito
No abstract text is available yet for this article.
March 9, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28318353/gender-differences-in-sexual-interest-or-activity-among-adults-with-symptomatic-heart-failure
#13
Stacy Fischer, David Bekelman
CONTEXT: Problems with sexual function can have a detrimental effect on quality of life. Symptomatic heart failure has been associated with problems with sexual function, although the majority of reports are focused on men and erectile dysfunction. Understanding women's perception of and gender differences in problems with sexual function in heart failure could yield new insights. OBJECTIVES: To determine the gender differences in reporting and bothersomeness of problems with sexual function, defined as sexual interest or activity...
March 20, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28315786/effects-of-bariatric-surgery-on-female-pelvic-floor-disorders
#14
Avner Leshem, Mordechai Shimonov, Hadar Amir, David Gordon, Asnat Groutz
OBJECTIVES: To assess the effect of weight loss on urinary incontinence (UI), pelvic organ prolapse, colorectal-anal complaints and sexual dysfunction among obese women undergoing bariatric surgery. METHODS: 160 consecutive women who underwent bariatric surgery were prospectively enrolled. Four validated questionnaires (ICIQ-UI, BFLUTS-SF, PFDI-20, PISQ-12) were used to evaluate pelvic floor disorders and sexual dysfunction before, and 3-6 months after surgery. RESULTS: 150 participants (mean age 43±12...
March 15, 2017: Urology
https://www.readbyqxmd.com/read/28315587/the-effect-of-l-thyroxine-treatment-on-sexual-function-and-depressive-symptoms-in-men-with-autoimmune-hypothyroidism
#15
Robert Krysiak, Witold Szkróbka, Bogusław Okopień
BACKGROUND: Thyroid autoimmunity and mild hypothyroidism in women seem to be associated with sexual dysfunction and depressive symptoms. Data concerning similar associations in men are limited. The aim of this study was to investigate sexual functioning and depressive symptoms in men with autoimmune hypothyroidism. METHODS: The study population consisted of three groups: men with autoimmune overt hypothyroidism (group A), men with autoimmune subclinical hypothyroidism (group B) and healthy euthyroid males without thyroid autoimmunity (group C)...
January 17, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28315500/relation-between-sexual-dysfunctions-and-epilepsy-type-of-epilepsy-type-of-antiepileptic-drugs-a-prospective-study
#16
Carlo Pavone, Ninfa Giacalone, Lidia Urso, Leila Zummo, Brigida Fierro
INTRODUCTION: The aim of this study was to evaluate the incidence of sexual dysfunctions in males with epilepsy, the type of epilepsy, the frequency of seizures, the type of antiepileptic drugs (AEDs), the serum hormonal profile and the presence of psychiatric comorbidity. METHODS: Sixty-one patients focused on type of epilepsy, frequency of seizures, AEDs, hormonal profile and presence of mood disorders. We excluded all patients with severe neurologic and psychiatric impairment and patient who were not able to fill questionnaires...
March 18, 2017: Urologia
https://www.readbyqxmd.com/read/28314966/-neuro-urological-diagnosis-and-therapy-of-lower-urinary-tract-dysfunction-in-patients-with-spinal-cord-injury-s2k-guideline-of-the-german-speaking-medical-society-of-paraplegia-dmgp-awmf-register-no-179-001
#17
R Böthig, B Domurath, A Kaufmann, J Bremer, W Vance, I Kurze
BACKGROUND: Most patients with spinal cord injury (SCI) suffer from neurogenic lower urinary tract dysfunction (NLUTD), bowel dysfunction and sexual dysfunction. If these remain untreated, severe medical complications and serious limitations (restrictions) in quality of life are imminent. OBJECTIVES: In the long term, there are considerable differences in the treatment results of highly specialized centers versus other treatment facilities. MATERIALS AND METHODS: Against this background, a consensus-based guideline, according to the AWMF (Association of the Scientific Medical Societies in Germany) criteria (S2k), was developed by the neuro-urology working group of the DMPG (German-Speaking Medical Society of Paraplegia)...
March 17, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28303465/pharmacotherapy-in-generalized-anxiety-disorder-novel-experimental-medicine-models-and-emerging-drug-targets
#18
REVIEW
David S Baldwin, Ruihua Hou, Robert Gordon, Nathan T M Huneke, Matthew Garner
Many pharmacological and psychological approaches have been found efficacious in patients with generalized anxiety disorder (GAD), but many treatment-seeking patients will not respond and others will relapse despite continuing with interventions that initially had beneficial effects. Other patients will respond but then stop treatment early because of untoward effects such as sexual dysfunction, drowsiness, and weight gain. There is much scope for the development of novel approaches that could have greater overall effectiveness or acceptability than currently available interventions or that have particular effectiveness in specific clinical subgroups...
March 16, 2017: CNS Drugs
https://www.readbyqxmd.com/read/28302931/the-comparison-of-the-effects-of-nebivolol-and-metoprolol-on-erectile-dysfunction-in-the-cases-with-coronary-artery-bypass-surgery
#19
Özcan Gür, Selami Gurkan, Gunduz Yumun, Polat Turker
PURPOSE: Beta-blocker use is common in the cases with coronary artery bypass surgery. According to the literature, beta-blockers have positive effects but may cause erectile dysfunction (ED). The most commonly used beta-blockers in ischemic cardiac disease are nebivolol and metoprolol. In our clinic, we aimed to compare the effects of nebivolol and metoprolol succinate on ED in the sexually active cases with coronary artery bypass surgery. METHODS: In our clinic, a total of 119 patients with coronary artery bypass surgery were included in the study...
March 10, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28302034/co-morbid-erectile-dysfunction-ed-and-antidepressant-treatment-in-a-patient-a-management-challenge
#20
Maszaidi Zainol, Hatta Sidi, Jaya Kumar, Srijit Das, Shaiful Ismail, Muhammad Hizri Hatta, Najwa Baharudin, Arun Ravindran
Across the globe, antidepressants (AD) and phosphodiesterase-5 inhibitors (PDE-5i) are commonly prescribed psychopharmacological agents for patients with co-morbid mental-health problem and sexual dysfunction (SD). The serotonergic and/or noradrenergic ADs, although is an effective agent are not without SD side-effects, especially erectile dysfunction (ED). ED is an inability to achieve, or maintain an erection for satisfactory sexual intercourse during the phases of male's sexual arousal. It is recognized as an important reason why non-adherence to treatment was observed in patients who are on AD...
March 15, 2017: Current Drug Targets
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