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Cardiac Resynchronization Therapy

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https://www.readbyqxmd.com/read/28641292/the-incidence-clinical-significance-and-treatment-effects-of-depression-in-cardiac-resynchronization-therapy-recipients
#1
Tomasz Podolecki, Robert Pudlo, Michal Mazurek, Monika Koziel, Ewa Jedrzejczyk-Patej, Joanna Boidol, Katarzyna Przybylska, Adam Sokal, Oskar Kowalski, Jacek Kowalczyk, Radoslaw Lenarczyk, Zbigniew Kalarus
OBJECTIVES: Chronic heart failure (HF) is associated with significantly increased prevalence of depression. The aim of the study was to assess the incidence and clinical impact of depression as well as the effectiveness of depression treatment in HF patients. METHODS: A prospective interventional trial included 285 consecutive cardiac resynchronization therapy recipients. Patients underwent a psychiatric examination at the time of implantation and then it was routinely repeated at 3, 6, and 12 months after the procedure, and every 6 months thereafter...
June 23, 2017: Cardiology
https://www.readbyqxmd.com/read/28636525/prognostic-significance-of-improvement-in-right-ventricular-systolic-function-during-cardiac-resynchronization-therapy
#2
Frederik Helsen, Alexander Van De Bruaene, Charlien Gabriels, Mathias Claeys, Els Troost, Gábor Vörös, Rik Willems, Jens-Uwe Voigt, Werner Budts
Objectives There is conflicting evidence concerning the role of right ventricular (RV) systolic dysfunction in the long-term clinical outcome after cardiac resynchronization therapy (CRT). Therefore we aimed to assess evolution of RV systolic function during CRT, covariates associated with its improvement, and its impact on outcome. Methods and results All CRT device implantations (Jan 2009-Dec 2011) in our institution were reviewed. Records of 69 patients (25% female, mean age 62.8 ± 9.2 years, mean left ventricular (LV) ejection fraction 27 ± 8%) were analyzed...
March 31, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28636517/imaging-in-the-field-of-cardiac-resynchronization-therapy-a-real-additive-value
#3
Erwan Donal, Alfredo Hernandez, Arnaud Hubert, Elena Galli, Anne Bernard
No abstract text is available yet for this article.
March 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28632280/implantable-cardioverter-defibrillators-for-primary-prevention-in-patients-with-ischemic-or-nonischemic-cardiomyopathy-a-systematic-review-and-meta-analysis
#4
Michalina Kolodziejczak, Felicita Andreotti, Mariusz Kowalewski, Antonino Buffon, Marco Matteo Ciccone, Gianfranco Parati, Pietro Scicchitano, Julia M Uminska, Stefano De Servi, Kevin P Bliden, Jacek Kubica, Alessandro Bortone, Filippo Crea, Paul Gurbel, Eliano P Navarese
Background: Implantable cardioverter-defibrillators (ICDs) have a role in preventing cardiac arrest in patients at risk for life-threatening ventricular arrhythmias. Purpose: To compare ICD therapy with conventional care for the primary prevention of death of various causes in adults with ischemic or nonischemic cardiomyopathy. Data Sources: MEDLINE, Cochrane Central Register of Controlled Trials, Google Scholar, and EMBASE databases, as well as several Web sites, from 1 April 1976 through 31 March 2017...
June 27, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28631238/is-it-time-for-personalized-cardiac-resynchronization-therapy
#5
EDITORIAL
Vineet Kumar
No abstract text is available yet for this article.
June 19, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28630171/distinctive-left-ventricular-activations-associated-with-ecg-pattern-in-heart-failure-patients
#6
Nicolas Derval, Josselin Duchateau, Saagar Mahida, Romain Eschalier, Frederic Sacher, Joost Lumens, Hubert Cochet, Arnaud Denis, Xavier Pillois, Seigo Yamashita, Yuki Komatsu, Sylvain Ploux, Sana Amraoui, Adlane Zemmoura, Philippe Ritter, Mélèze Hocini, Michel Haissaguerre, Pierre Jaïs, Pierre Bordachar
BACKGROUND: In contrast to patients with left bundle branch block (LBBB), heart failure patients with narrow QRS and nonspecific intraventricular conduction delay (NICD) display a relatively limited response to cardiac resynchronization therapy. We sought to compare left ventricular (LV) activation patterns in heart failure patients with narrow QRS and NICD to patients with LBBB using high-density electroanatomic activation maps. METHODS AND RESULTS: Fifty-two heart failure patients (narrow QRS [n=18], LBBB [n=11], NICD [n=23]) underwent 3-dimensional electroanatomic mapping with a high density of mapping points (387±349 LV)...
June 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28626904/do-real-world-data-support-and-extend-our-ability-to-predict-reverse-remodelling-following-cardiac-resynchronization-therapy-based-on-qrs-morphology-and-width
#7
EDITORIAL
Torkel Steen, Kenneth Dickstein
No abstract text is available yet for this article.
June 19, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28626201/survival-and-heart-failure-hospitalization-in-patients-with-cardiac-resynchronization-therapy-with-or-without-a-defibrillator-for-primary-prevention-in-japan%C3%A3-analysis-of-the-japan-cardiac-device-treatment-registry-database
#8
Hisashi Yokoshiki, Akihiko Shimizu, Takeshi Mitsuhashi, Hiroshi Furushima, Yukio Sekiguchi, Tetsuyuki Manaka, Nobuhiro Nishii, Takeshi Ueyama, Norishige Morita, Hideo Okamura, Takashi Nitta, Kenzo Hirao, Ken Okumura
BACKGROUND: Randomized control trials comparing the effectiveness of cardiac resynchronization therapy devices, with (CRT-D) or without (CRT-P) a defibrillator, are scarce in heart failure patients with no prior sustained ventricular tachyarrhythmias.Methods and Results:The Japan Cardiac Device Treatment Registry (JCDTR) has data for 2714 CRT-D and 555 CRT-P recipients for primary prevention with an implantation date between January 2011 and August 2015. Of these patients, follow-up data were available for 717...
June 13, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28625381/utilization-of-cardiac-resynchronization-therapy-in-eligible-patients-hospitalized-for-heart-failure-and-its-association-with-patient-outcomes
#9
Tiffany C Randolph, Anne S Hellkamp, Emily P Zeitler, Gregg C Fonarow, Adrian F Hernandez, Kevin L Thomas, Eric D Peterson, Clyde W Yancy, Sana M Al-Khatib
OBJECTIVES: We examined trends in CRT utilization overall and by sex and race and to assess whether CRT use is associated with a reduction in HF hospitalization and mortality. BACKGROUND: It is unknown whether underutilization and race/sex-based differences in cardiac resynchronization therapy (CRT) use have persisted. The association between CRT and heart failure (HF) hospitalization and mortality in real-world practice remains unclear. METHODS: We linked 72,008 HF patients from 388 hospitals participating in Get With The Guidelines HF eligible for CRT with Centers for Medicare & Medicaid Services data to assess CRT utilization trends, HF hospitalization rates, and all-cause mortality...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28623910/pilot-study-using-3d-longitudinal-strain-computation-in-a-multi-parametric-approach-for-best-selecting-responders-to-cardiac-resynchronization-therapy
#10
Maxime Fournet, Anne Bernard, Sylvestre Marechaux, Elena Galli, Raphael Martins, Philippe Mabo, J Claude Daubert, Christophe Leclercq, Alfredo Hernandez, Erwan Donal
BACKGROUND: Almost all attempts to improve patient selection for cardiac resynchronization therapy (CRT) using echo-derived indices have failed so far. We sought to assess: the performance of homemade software for the automatic quantification of integral 3D regional longitudinal strain curves exploring left ventricular (LV) mechanics and the potential value of this tool to predict CRT response. METHODS: Forty-eight heart failure patients in sinus rhythm, referred for CRT-implantation (mean age: 65 years; LV-ejection fraction: 26%; QRS-duration: 160 milliseconds) were prospectively explored...
June 17, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28619695/a-prolonged-pr-interval-an-unfavorable-shareholder-of-the-profits-of-cardiac-resynchronization-therapy
#11
EDITORIAL
Norbert M van Hemel
No abstract text is available yet for this article.
June 12, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28614025/cardiac-resynchronization-therapy-and-its-role-in-the-management-of-heart-failure
#12
Christopher J McAloon, Mark D Theodoreson, Sajad Hayat, Faizel Osman
The prevalence of heart failure is increasing and it is associated with significant mortality and morbidity. Optimal medical therapy improves outcome, but heart failure continues to have a substantial impact on both the individual patient and wider society. Over the last two decades, cardiac resynchronization therapy has revolutionized the treatment of selected patients who have heart failure. Cardiac resynchronization therapy significantly reduces mortality and hospitalization through reverse cardiac remodelling...
June 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28608184/assessment-of-left-ventricular-contraction-patterns-using-gated-spect-mpi-to-predict-cardiac-resynchronization-therapy-response
#13
Ningchao Tao, Yuanhao Qiu, Haipeng Tang, Zhiyong Qian, Hongping Wu, Rui Zhu, Yao Wang, Xiaofeng Hou, Weihua Zhou, Jiangang Zou
BACKGROUND: The U-shaped left ventricular (LV) contraction pattern, identified by MRI or echocardiography, is associated with improved CRT response. Gated SPECT MPI can measure both myocardial viability and mechanical dyssynchrony in a single scan. The aim of this study is to examine the relationship of the LV contraction pattern and the response of CRT in patients with left bundle branch block (LBBB). METHODS: Fifty-eight patients who met CRT guidelines and who had pre-CRT MPI were enrolled...
June 12, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28603001/low-lateral-thoracic-site-for-cardiac-implantable-electronic-device-implantation-a-viable-alternative-in-patients-with-limited-access-options-after-infected-device-extraction
#14
Jackson J Liang, Robert D Schaller, Danesh S Modi, Andres Enriquez, Gregory E Supple, Joshua M Cooper
BACKGROUND: Device reimplantation after extraction due to cardiac implantable electronic device (CIED) infection in pacemaker-dependent patients can be challenging in patients with limited access options. OBJECTIVE: We describe a straight-forward, low lateral thoracic implantation technique for patients with a patent axillary vein but unavailable bilateral pectoral sites. METHODS: We included 9 pacemaker-dependent patients (mean age 70±13, 7 male) who underwent CIED extraction and low lateral thoracic reimplant, in whom bilateral pectoral sites were unavailable...
June 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28602373/cardiac-resynchronization-therapy-in-older-adults-with%C3%A2-heart-failure
#15
REVIEW
Phillip H Lam, George E Taffet, Ali Ahmed, Steve Singh
Heart failure is a disease of poor prognosis marked by frequent hospitalizations, premature death, and impaired quality of life. Despite advances in medical therapy for patients with heart failure and reduced ejection fraction, mortality and hospitalizations with advanced disease are still increased and the quality of life continues to be poor in this population. The advent of cardiac resynchronization therapy has led to a significant improvement in both survival and symptom management in patients with heart failure and reduced ejection fraction...
July 2017: Heart Failure Clinics
https://www.readbyqxmd.com/read/28602366/treatment-of-heart-failure-with-abnormal-left-ventricular-systolic-function-in-older-adults
#16
REVIEW
Wilbert S Aronow
Heart failure (HF) with abnormal left ventricular (LV) ejection fraction should be identified and treated. Treat hypertension with diuretics, angiotensin-converting enzyme (ACE) inhibitors, and β-blockers. Treat myocardial ischemia with nitrates and β-blockers. Treat volume overload and HF with diuretics. Treat HF with ACE inhibitors and β-blockers. Sacubitril/valsartan may be used instead of an ACE inhibitor or ARB in chronic symptomatic HF and abnormal LV ejection fraction. Add isosorbide dinitrate/hydralazine in African Americans with class II to IV HF treated with diuretics, ACE inhibitors, and β-blockers...
July 2017: Heart Failure Clinics
https://www.readbyqxmd.com/read/28602228/universal-response-to-cardiac-resynchronization-therapy-a-challenge-still-to-be-overcome
#17
António Hipólito Reis
No abstract text is available yet for this article.
June 8, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28601914/left-ventricular-ejection-fraction-as-therapeutic-target-is-it-the-ideal-marker
#18
REVIEW
V Katsi, G Georgiopoulos, A Laina, E Koutli, J Parissis, C Tsioufis, P Nihoyannopoulos, D Tousoulis
Heart failure (HF) consists the fastest growing clinical cardiac disease. HF patients are categorized on the basis of underlying left ventricular ejection fraction (LVEF) into HF with preserved EF (HFpEF), reduced LVEF (HFrEF), and mid-range LVEF (HFmrEF). While LVEF is the most commonly used surrogate marker of left ventricular (LV) systolic function, the implementation of two-dimensional echocardiography in estimating this parameter imposes certain caveats on current HF classification. Most importantly, LVEF could fluctuate in repeated measurements or even recover after treatment, thus blunting the borders between proposed categories of HF and enabling upward classification of patients...
June 10, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28600804/noninvasive-pulmonary-transit-time-a-new-parameter-for-general-cardiac-performance
#19
Anouk G W de Lepper, Ingeborg H F Herold, Salvatore Saporito, R Arthur Bouwman, Massimo Mischi, Hendrikus H M Korsten, Koen D Reesink, Patrick Houthuizen
INTRODUCTION: Pulmonary transit time (PTT) assessed with contrast-enhanced ultrasound (CEUS) is a novel tool to evaluate cardiac function. PTT represents the time for a bolus of contrast to pass from the right to the left ventricle, measured according to the indicator dilution principles using CEUS. We investigated the hypothesis that PTT is a measure of general cardiac performance in patient populations eligible for cardiac resynchronization therapy (CRT). METHODS: The study population consisted of heart failure patients referred for CRT with NYHA class II-IV, left ventricular ejection fraction (LVEF)≤35% and QRS≥120 ms...
June 9, 2017: Echocardiography
https://www.readbyqxmd.com/read/28600101/non-cardiac-factors-for-prediction-of-response-to-cardiac-resynchronization-therapy-the-value-of-baseline-and-of-serial-changes-in-red-cell-distribution-width
#20
Erberto Carluccio, Paolo Biagioli, Gianfranco Alunni, Adriano Murrone, Gianluca Zingarini, Stefano Coiro, Antonella D'Antonio, Anna Mengoni, Maria Francesca Cerasa, Giuseppe Ambrosio
BACKGROUND: Increased red blood cell distribution width (RDW) has been associated with poor outcome after cardiac resynchronization therapy (CRT). However, whether baseline RDW, and its serial changes after CRT implant, have incremental prognostic value is unknown. METHODS AND RESULTS: In 148 consecutive patients (age, 68±9years; 122 men) undergoing CRT, RDW was assessed before and 3months after implant. Patients were categorized according to baseline RDW (≤14...
June 2, 2017: International Journal of Cardiology
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