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Apparent Life Threatening Event

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https://www.readbyqxmd.com/read/27749633/etiology-and-outcome-of-severe-apparent-life-threatening-events-in-infants
#1
Tanja Radovanovic, Slobodan Spasojevic, Vesna Stojanovic, Aleksandra Doronjski
INTRODUCTION: An apparent life-threatening event (ALTE) is defined as "an episode that is frightening to the observer and is characterized by some combination of apnea, color change, marked change of muscle tone, choking, or gagging." OBJECTIVE: The aims of this study were to determine etiology and outcome of severe ALTE (requiring resuscitation measures) and to review diagnostic approaches in infants hospitalized after such an episode of ALTE. METHODS: Retrospective analysis included patients hospitalized at the Intensive Care Unit, Institute of Child and Youth Healthcare of Vojvodina, after an episode of severe ALTE over a 4-year period...
September 30, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27741078/the-utility-of-head-computed-tomography-in-the-evaluation-of-apparent-life-threatening-event
#2
Wayne Stark, Annie Rominger, Fred Warkentine, Kerry Caperell
OBJECTIVE: This study aimed to evaluate the diagnostic utility of empiric head computed tomography (CT) in apparent life threatening event (ALTE). METHODS: This was a retrospective chart review of children younger than 12 months presenting to an urban pediatric hospital and its suburban satellite for an ALTE from October 2009 to December 2012. The ALTE cases were identified as having had a diagnosis of ALTE (International Classification of Diseases, 9th Revision 799...
October 6, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27741062/oropharyngeal-dysphagia-is-strongly-correlated-with-apparent-life-threatening-events
#3
Daniel R Duncan, Janine Amirault, Paul Mitchell, Kara Larson, Rachel L Rosen
OBJECTIVES: The aim of this study was to investigate the prevalence of oropharyngeal dysfunction with resultant aspiration in patients admitted after apparent life-threatening event (ALTE) and to determine if historical characteristics could predict this oropharyngeal dysphagia and aspiration risk. METHODS: We retrospectively reviewed the records of all patients admitted to Boston Children's Hospital between 2012 and 2015 with a diagnosis of ALTE to determine the frequency of evaluation for oropharyngeal dysphagia using videofluoroscopic swallow studies (VFSS) and clinical feeding evaluations, to determine the prevalence of swallowing dysfunction in subjects admitted after ALTE and to compare presenting historical characteristics to swallow study results RESULTS:: 188 children were admitted with a diagnosis of ALTE of which 29% (n = 55) had an assessment of swallowing by VFSS...
October 12, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27737774/exploring-the-safety-and-efficacy-of-targeted-temperature-management-amongst-infants-with-out-of-hospital-cardiac-arrest-due-to-apparent-life-threatening-events
#4
Kathleen Meert, Russell Telford, Richard Holubkov, Beth S Slomine, James R Christensen, J Michael Dean, Frank W Moler
OBJECTIVE: To explore the safety and efficacy of targeted temperature management amongst infants with out-of-hospital cardiac arrest due to an apparent life threatening event (ALTE) recruited to the Therapeutic Hypothermia after Paediatric Cardiac Arrest Out-of-Hospital trial. METHODS: Fifty-four infants (48h to <1year of age) with ALTE who received chest compressions for ≥2min, were comatose, and required mechanical ventilation after return of circulation were included...
December 2016: Resuscitation
https://www.readbyqxmd.com/read/27736023/b12-deficiency-is-common-in-infants-and-is-accompanied-by-serious-neurological-symptoms
#5
T Irevall, I Axelsson, E Naumburg
AIM: Adverse neurological symptoms have been linked to vitamin B12 deficiency in infants. This explorative study described the clinical presentation associated with vitamin B12 deficiency in this age group. METHODS: The study comprised infants who were born between 2004 and 2012 and were tested for vitamin B12 levels after they were admitted to a hospital with neurological symptoms at less than one year of age. Vitamin B12 deficiency was defined as low cobalamin in serum and/or increased homocysteine and/or increased methylmalonate...
October 13, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27726123/psychological-therapies-for-children-and-adolescents-exposed-to-trauma
#6
REVIEW
Donna Gillies, Licia Maiocchi, Abhishta P Bhandari, Fiona Taylor, Carl Gray, Louise O'Brien
BACKGROUND: Children and adolescents who have experienced trauma are at high risk of developing post-traumatic stress disorder (PTSD) and other negative emotional, behavioural and mental health outcomes, all of which are associated with high personal and health costs. A wide range of psychological treatments are used to prevent negative outcomes associated with trauma in children and adolescents. OBJECTIVES: To assess the effects of psychological therapies in preventing PTSD and associated negative emotional, behavioural and mental health outcomes in children and adolescents who have undergone a traumatic event...
October 11, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27722004/alte-and-feeding-intolerance-as-a-presentation-of-double-aortic-arch
#7
Rekha Krishnasarma, Liza Green Golan Mackintosh, Francine Bynum
Many children who are admitted to pediatric hospitals with the chief complaint of apparent life-threatening event (ALTE) are, in fact, well appearing by the time the inpatient medical team evaluates the patient. This presents a diagnostic and therapeutic challenge. We describe a case of a six-month-old full-term female presenting with an ALTE and found to have a double aortic arch, a congenital anomaly that usually presents with a more progressive onset of symptoms such as chronic cough, positional stridor, and feeding difficulties...
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/27721838/apparent-life-threatening-event-in-infancy
#8
Hee Joung Choi, Yeo Hyang Kim
An apparent life-threatening event (ALTE) is defined as the combination of clinical presentations such as apnea, marked change in skin and muscle tone, gagging, or choking. It is a frightening event, and it predominantly occurs during infancy at a mean age of 1-3 months. The causes of ALTE are categorized into problems that are: gastrointestinal (50%), neurological (30%), respiratory (20%), cardiovascular (5%), metabolic and endocrine (2%-5%), or others such as child abuse. Up to 50% of ALTEs are idiopathic, where the cause cannot be diagnosed...
September 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27712572/old-new-and-hidden-causes-of-perioperative-hypersensitivity
#9
Lene H Garvey
Perioperative hypersensitivity reactions are rare, often life-threatening events, and subsequent investigations to identify the culprit are important to avoid re-exposure. All exposures in the perioperative setting may potentially be the cause of a hypersensitivity reaction, but drugs administered intravenously such as neuromuscular blocking agents (NMBA), induction agents and antibiotics have traditionally been reported to be implicated most commonly. It has recently become apparent that there are geographical differences in sensitization patterns related to variation in exposures, referral patterns and performance and interpretation of investigations...
October 4, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27614656/weight-loss-and-decubitus-duodenal-ulcer-in-parkinson-s-disease-treated-with-levodopa-carbidopa-intestinal-gel-infusion
#10
Tommaso Martino, Donato Melchionda, Paolo Tonti, Vincenzo De Francesco, Alessandra Lalla, Luigi Maria Specchio, Carlo Avolio
Apparently, unexplained weight loss is a common symptom experienced by patients affected by Parkinson's disease, especially in those treated by levodopa-carbidopa infusion gel (LCIG) with a poor control of dyskinesias. Weight loss is considered part of gastrointestinal dysfunction seen in patients affected by Parkinson's disease, along with gastroparesis and reduced bowel peristalsis. In patients treated with LCIG, weight loss needs to be accurately evaluated, because of possible underlying life-threatening adverse events, like duodenum decubitus ulcer...
December 2016: Journal of Neural Transmission
https://www.readbyqxmd.com/read/27479062/premature-infants-rehospitalized-because-of-an-apparent-life-threatening-event-had-distinctive-autonomic-developmental-trajectories
#11
Gustavo Nino, R B Govindan, Tareq Al-Shargabi, Marina Metzler, An N Massaro, Geovanny F Perez, Robert McCarter, Carl E Hunt, Adre J du Plessis
No abstract text is available yet for this article.
August 1, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27474017/tieder-js-bonkowsky-jl-etzel-ra-et-al-clinical-practice-guideline-brief-resolved-unexplained-events-formerly-apparent-life-threatening-events-and-evaluation-of-lower-risk-infants-executive-summary-pediatrics-2016-137-5-e20160591
#12
https://www.readbyqxmd.com/read/27474014/tieder-js-bonkowsky-jl-etzel-ra-et-al-clinical-practice-guideline-brief-resolved-unexplained-events-formerly-apparent-life-threatening-events-and-evaluation-of-lower-risk-infants-pediatrics-2016-137-5-e20160590
#13
https://www.readbyqxmd.com/read/27435495/infants-dying-suddenly-and-unexpectedly-share-demographic-features-with-infants-who-die-with-retinal-and-dural-bleeding-a-review-of-neural-mechanisms
#14
REVIEW
Waney Squier, Julie Mack, Anna C Jansen
The cause of death in infants who die suddenly and unexpectedly (sudden unexpected death in infancy [SUDI]) remains a diagnostic challenge. Some infants have identified diseases (explained SUDI); those without explanation are called sudden infant death syndrome (SIDS). Demographic data indicate subgroups among SUDI and SIDS cases, such as unsafe sleeping and apparent life-threatening events. Infants dying suddenly with retinal and dural bleeding are often classified as abused, but in many there is no evidence of trauma...
December 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27415643/apparent-life-threatening-events-helping-infants-help-themselves
#15
Alessandro Vigo, Roberto Balagna, Luca Brazzi, Giulia Costagliola, Cesare Gregoretti, Maria Maddalena Lupica, Silvia Noce
OBJECTIVES: Apparent life-threatening event (ALTE) refers to a constellation of unexpected events suddenly occurring in infants that extremely alarm the observers. The objectives of this study were to evaluate 1) intervention of Emergency Service (ES) at home, 2) parental behavior before ES intervention, 3) patients' outcome at follow-up of a minimum of 6 months. METHODS: Retrospective study of infants younger than 12 months whose parents called ES and were evaluated for ALTE from 2005 to 2014...
July 9, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27295900/-how-i-explore-an-apparent-life-threatening-event-of-the-infant
#16
L Zambelli, O Battisti
The ALTE (Apparent Life Threatening Event) of the infant is a frequent presenting complaint. The clinical presentation is varied, ranging from an innocuous event (as a change in skin color) to something as tragic as a sudden infant death. In all circumstances, it is always a very worrying event for the parents and the family circle. Many etiologies can explain the ALTE, and their investigation can be complicated. In this paper, the etiologies and diagnostic tests will be briefly introduced, with a reminder of the sudden infant death syndrome...
April 2016: Revue Médicale de Liège
https://www.readbyqxmd.com/read/27293941/a-case-of-apparent-life-threatening-event-comorbid-gastric-volvulus-associated-gastroesophageal-reflux-disease-and-epilepsy-in-a-4-month-old-boy
#17
Yoshihiko Takano, Masaki Horiike, Ako Tatsumi, Haruko Sakamoto, Hisanori Fujino, Shin-Ichi Sumimoto
Most isolated episodes of apparent life-threatening events (ALTEs) do not lead to the diagnosis of serious conditions, and their prognoses are generally benign. However, recurrent ALTEs are often associated with a risk of future serious adverse events and should be evaluated for appropriate management. Here we present ALTE case in which gastric volvulus associated gastroesophageal reflux disease was detected as an etiology initially, followed by the detection of epilepsy as another etiology. Clinicians should consider possibility of two or more etiologies in a single recurrent ALTE case...
2016: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/27262544/acid-gastroesophageal-reflux-disease-and-apparent-life-threatening-events-simultaneous-ph-metry-and-cardiorespiratory-monitoring
#18
Francesco Macchini, Anna Morandi, Paola Cognizzoli, Giorgio Farris, Valerio Gentilino, Andrea Zanini, Ernesto Leva
AIM: To investigate the prevalence and the characteristics of gastroesophageal reflux disease (GERD) in infants with apparent life threatening events (ALTE). MATERIALS AND METHODS: Infants with at least one episode of ALTE in absence of predisposing factors were included. All infants underwent a cardiorespiratory recording with simultaneous 24-hour pH-monitoring. Patients were divided into 3 groups according to the severity of GERD: A. Reflux Index (RI) <3%, B...
May 13, 2016: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/27244836/brief-resolved-unexplained-events-formerly-apparent-life-threatening-events-and-evaluation-of-lower-risk-infants-executive-summary
#19
Joel S Tieder, Joshua L Bonkowsky, Ruth A Etzel, Wayne H Franklin, David A Gremse, Bruce Herman, Eliot S Katz, Leonard R Krilov, J Lawrence Merritt, Chuck Norlin, Jack Percelay, Robert E Sapién, Richard N Shiffman, Michael B H Smith
No abstract text is available yet for this article.
May 2016: Pediatrics
https://www.readbyqxmd.com/read/27244835/brief-resolved-unexplained-events-formerly-apparent-life-threatening-events-and-evaluation-of-lower-risk-infants
#20
Joel S Tieder, Joshua L Bonkowsky, Ruth A Etzel, Wayne H Franklin, David A Gremse, Bruce Herman, Eliot S Katz, Leonard R Krilov, J Lawrence Merritt, Chuck Norlin, Jack Percelay, Robert E Sapién, Richard N Shiffman, Michael B H Smith
This is the first clinical practice guideline from the American Academy of Pediatrics that specifically applies to patients who have experienced an apparent life-threatening event (ALTE). This clinical practice guideline has 3 objectives. First, it recommends the replacement of the term ALTE with a new term, brief resolved unexplained event (BRUE). Second, it provides an approach to patient evaluation that is based on the risk that the infant will have a repeat event or has a serious underlying disorder. Finally, it provides management recommendations, or key action statements, for lower-risk infants...
May 2016: Pediatrics
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