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cervical disc arthroplasty

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https://www.readbyqxmd.com/read/29427744/towards-the-scale-up-of-tissue-engineered-intervertebral-discs-for-clinical-application
#1
Sarah E Gullbrand, Dong Hwa Kim, Edward Bonnevie, Beth G Ashinsky, Lachlan J Smith, Dawn M Elliott, Robert L Mauck, Harvey E Smith
Replacement of the intervertebral disc with a viable, tissue-engineered construct that mimics native tissue structure and function is an attractive alternative to fusion or mechanical arthroplasty for the treatment of disc pathology. While a number of engineered discs have been developed, the average size of these constructs remains a fraction of the size of human intervertebral discs. In this study, we fabricated medium (3 mm height x 10 mm diameter) and large (6 mm height x 20 mm diameter) sized disc-like angle ply structures (DAPS), encompassing size scales from the rabbit lumbar spine to the human cervical spine...
February 7, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29415694/in-vivo-study-of-osseointegration-in-prestige-lp-cervical-disc-prosthesis
#2
Jigang Lou, Beiyu Wang, Tingkui Wu, Wenjie Wu, Huibo Li, Ziyang Liu, Hao Liu
BACKGROUND: A study was designed to quantify the extent of porous osseointegration at the prosthesis-bone interface in the Prestige LP prosthesis containing a plasma-sprayed titanium coating. METHODS: Using an anterior surgical approach, cervical disc arthroplasty was performed in 8 mature male goats at the C3-C4 segment, followed by implantation of the Prestige LP prosthesis. The vertebral specimens were examined using microcomputed tomograph for histomorphometric quantification, and proceeded by routine paraffin processing for histological observation...
February 7, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29409935/comparison-between-cervical-disc-arthroplasty-and-conservative-treatment-for-patients-with-single-level-cervical-radiculopathy-at-c5-6
#3
Axiang He, Dong Xie, Bo Qu, Xiaomin Cai, Qin Kong, Lili Yang, Xiongsheng Chen, Lianshun Jia
BACKGROUND: Cervical radiculopathy is a common disease that affects millions of people. Patients usually are managed by conservative therapy and surgical treatments. OBJECTIVE: To compare the clinical outcomes between cervical disc arthroplasty (CDA) and conservative management for patients with single level cervical radiculopathy at C5/6. METHODS: Seventy-two patients with cervical radiculopathy that only affect C5/6 joints were included and thirty-two of them received CDA surgery, and forty patients were treated with conservative management...
January 30, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29393833/myelopathy-after-cervical-disc-arthroplasty-due-to-progression-of-spondylosis-at-the-index-level-case-report
#4
Anita Bhansali, Michael Musacchio, Noam Stadlan
Cervical disc arthroplasty (CDA) has emerged as a popular alternative to anterior cervical discectomy and fusion (ACDF) for the surgical treatment of cervical degenerative disc disease. CDA has been well studied, with efficacy reported to be equivalent to or better than that seen with ACDF, and it is associated with a consistently low incidence of adverse events. The development or progression of myelopathy after CDA is a particularly rare occurrence. In this report, the authors describe the first known case of recurrence of myelopathy at the index level of surgery after CDA implantation due the continuation of the spondylitic process after placement of the artificial disc...
February 2, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29393832/letter-to-the-editor-hybrid-cervical-disc-arthroplasty-for-cervical-myelopathy-associated-with-congenital-cervical-stenosis
#5
Yawei Li, Guohua Lv, Bing Wang
No abstract text is available yet for this article.
February 2, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29378457/review-of-long-term-outcomes-of-disc-arthroplasty-for-symptomatic-single-level-cervical-degenerative-disc-disease
#6
Siddharth A Badve, Pierce D Nunley, Swamy Kurra, William F Lavelle
Cervical disc arthroplasty (CDA) was developed as an alternative for anterior cervical discectomy and fusion (ACDF) for nerve root decompression. The rationale behind CDA was to help prevent adjacent segment degeneration which potentially may lead to additional surgery. Multiple randomized controlled trials have evaluated a myriad of disc arthroplasty devices over the past 10 years and provided data regarding clinical benefits and safety. Their long-term data, reporting results at 5-10 years, presents the opportunity to comment on the overall efficacy, safety and reported complications of these devices...
January 30, 2018: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29369186/cervical-disc-arthroplasty-with-prestige-lp-for-the-treatment-of-contiguous-2-level-cervical-degenerative-disc-disease-5-year-follow-up-results
#7
Xinlin Gao, Yi Yang, Hao Liu, Yang Meng, Junfeng Zeng, Tingkui Wu, Ying Hong
The objective of this study is to present the long-term results and to evaluate the safety and effectiveness of the Prestige-LP cervical disc replacement in treatment of patients with symptomatic 2-level cervical degenerative disc disease.Twenty-four patients with 48 Prestige-LP disc were analyzed before surgery and at 1 week, 3 months, 6 months, 12 months, 24 months, and 60 months after surgery. Clinical assessments included 36-Short Form (SF-36), Japanese Orthopedic Assessment (JOA), visual analog scale (VAS), and Neck Disability Index (NDI) scores...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29354749/focal-hypermobility-observed-in-cervical-arthroplasty-with-mobi-c
#8
Jack William Kerferd, David Abi-Hanna, Kevin Phan, Prashanth Rao, Ralph J Mobbs
In recent decades cervical arthroplasty, or cervical disc replacement, has been steadily increasing in popularity as a procedure for the treatment of degenerative pathologies of the cervical spine. This is based on an evolving body of literature that documents superior outcomes in cervical disc replacement over fusion, for both single and double level pathologies, in well selected patients. One of the more recent and popular implants currently on the market is the Mobi-C cervical artificial disc (LDR Medical; Troyes, France)...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29354743/national-outcomes-following-single-level-cervical-disc-arthroplasty-versus-anterior-cervical-discectomy-and-fusion
#9
Jamal Shillingford, Joseph Laratta, Nathan Hardy, Comron Saifi, Joseph Lombardi, Andrew J Pugely, Ronald A Lehman, K Daniel Riew
Background: To compare the differences in the thirty-day postoperative outcomes between cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF). Methods: Patients undergoing primary single-level ACDF and CDA from 2010-2014 were identified by unique Current Procedural Terminology (CPT) codes within the American College of Surgeon's National Surgical Quality Improvement Program (NSQIP) database. Primary outcomes included surgical and medical complications, length of hospital stay (LOS), unplanned readmission, return to operating room, and mortality all occurring within 30 days of the initial procedure...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29325074/cervical-disc-arthroplasty-current-evidence-and-real-world-application
#10
Pierce D Nunley, Domagoj Coric, Kelly A Frank, Marcus B Stone
Cervical total disc replacement (cTDR) is still considered a developing technology, with widespread clinical use beginning in the early 2000s. Despite being relatively new to the marketplace, the literature surrounding cTDR is abundant. We conducted a thorough review of literature published in the United States (US) and outside the US to report the current global state of cTDR research and clinical use. Search criteria were restricted to publications with a clinical patient population, excluding finite element analyses, biomechanical studies, cadaver studies, surgical technique-specific papers, and case studies...
January 6, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29303467/prospective-randomized-multicenter-study-of-cervical-arthroplasty-versus-anterior-cervical-discectomy-and-fusion-5-year-results-with-a-metal-on-metal-artificial-disc
#11
Domagoj Coric, Richard D Guyer, Pierce D Nunley, David Musante, Cameron Carmody, Charles Gordon, Carl Lauryssen, Margaret O Boltes, Donna D Ohnmeiss
OBJECTIVE Seven cervical total disc replacement (TDR) devices have received FDA approval since 2006. These devices represent a heterogeneous assortment of implants made from various biomaterials with different biomechanical properties. The majority of these devices are composed of metallic endplates with a polymer core. In this prospective, randomized multicenter study, the authors evaluate the safety and efficacy of a metal-on-metal (MoM) TDR (Kineflex|C) versus anterior cervical discectomy and fusion (ACDF) in the treatment of single-level spondylosis with radiculopathy through a long-term (5-year) follow-up...
January 5, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29279750/anterior-longitudinal-ligament-reconstruction-to-reduce-hypermobility-of-cervical-and-lumbar-disc-arthroplasty
#12
Ralph J Mobbs, Jia Xi Julian Li, Kevin Phan
Study Design: Retrospective case series. Purpose: This study aims to present the early clinical and radiological outcomes of anterior longitudinal ligament (ALL) reconstruction following disc arthroplasty. Overview of Literature: Although cervical and lumbar disc arthroplasty have entered the clinical setting, there are still concerns regarding the short and long term complications arising from hypermobility of current prosthesis designs. Reconstruction of the ALL is a potential solution to disc arthroplasty hypermobility...
December 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29222937/preoperative-t1-slope-as-a-predictor-of-change-in-cervical-alignment-and-range-of-motion-after-cervical-disc-arthroplasty
#13
Jianhui Zhao, Rui Jiang, Yuhui Yang, Rui Gu, Zhongli Gao, Jianlin Xiao, Shangjun Chen, Modi Yang
BACKGROUND This study analyzed the effect of preoperative T1 slope on cervical alignment and range of motion (ROM) after cervical disc arthroplasty (CDA) in patients with cervical degenerative disease. MATERIAL AND METHODS This retrospective study included 32 patients with single-level symptomatic cervical disc disease who underwent CDA with the Mobi-C cervical disc prosthesis and had a mean follow-up of 26.8±6.4 months. Standing lateral, flexion, and extension X-rays of the cervical spine were obtained preoperatively and postoperatively at 24-month follow-up...
December 9, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29216503/clinical-and-radiographic-comparison-of-cervical-disc-arthroplasty-with-prestige-lp-disc-and-anterior-cervical-fusion-a-minimum-6-year-follow-up-study
#14
Junfeng Zeng, Hao Liu, Beiyu Wang, Yuxiao Deng, Chen Ding, Hua Chen, Yi Yang, Ying Hong, Ning Ning
OBJECTIVES: To retrospectively compare the long-term clinical and radiographic outcomes of cervical disc arthroplasty (CDA) with Prestige-LP Disc and anterior cervical discectomy and fusion (ACDF) for single-level cervical degenerative disc disease. PATIENTS AND METHODS: Ninety-eight patients (45 CDA and 53 ACDF) with a minimum 6-year follow-up were included. Clinical evaluations included Japanese Orthopedic Association (JOA), visual analogue scale (VAS), and Neck Disability Index (NDI) scores...
December 4, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29189218/adjacent-level-degeneration-bryan-total-disc-arthroplasty-versus-anterior-cervical-discectomy-and-fusion
#15
Justin Miller, Rick Sasso, Paul Anderson, K Daniel Riew, Austin McPhilamy, Thomas Gianaris
STUDY DESIGN: Prospective randomized, 2-center, clinical trial. OBJECTIVE: To prospectively compare adjacent level degeneration between the Bryan Cervical Disc Prosthesis and anterior cervical discectomy and fusion (ACDF), and assess the reliability of our measurements utilizing a method not previously described. SUMMARY OF BACKGROUND DATA: ACDF is a reliable and proven procedure for the treatment of radiculopathy and/or myelopathy. Despite a successful track record several limitations including adjacent segment degeneration/disease, loss of viscoelastic disc properties, perioperative immobilization, graft site morbidity, pseudarthrosis, and plating complications have been identified...
November 16, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29164328/metallosis-after-traumatic-loosening-of-bryan-cervical-disc-arthroplasty-a-case-report-and-literature-review
#16
Chih-Chan Yang, Chien-Lun Tang, Chung-Yuh Tzeng, Hsi-Kai Tsou
PURPOSE: Cervical disc arthroplasty has been a popular alternative to traditional arthrodesis treatment for maintaining postoperative cervical spine mobility. However, certain adverse reactions to cervical disc arthroplasty have emerged during the last few decades. METHODS: Metallosis or metalloma is a rarely reported complication after spinal fusion or spinal arthroplasty surgery. We report on the first metallosis case occurring in a patient who received Bryan Disc implantation approximately 8 years earlier...
November 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29128581/trends-in-resource-utilization-and-rate-of-cervical-disc-arthroplasty-and-anterior-cervical-discectomy-and-fusion-throughout-the-united-states-from-2006-to-2013
#17
Comron Saifi, Arielle Fein, Alejandro Cazzulino, Ronald Lehman, Frank M Phillips, Howard S An, K Daniel Riew
BACKGROUND CONTEXT: The typically accepted surgical procedure for cervical disc pathology has been the anterior cervical discectomy and fusion (ACDF), although recent trials have demonstrated equivalent or improved outcomes with cervical disc arthroplasty (CDA). Trends for these two procedures regarding utilization, revision procedures, along with other demographic information have not been sufficiently explored. PURPOSE: To provide data regarding ACDF and CDA from 2006-2013 in the U...
November 8, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29076467/-analysis-of-the-results-of-total-cervical-disc-arthroplasty-using-a-m6-c-prosthesis-a-multicenter-study
#18
V A Byval'tsev, A A Kalinin, I A Stepanov, Yu Ya Pestryakov, V V Shepelev
Cervical spondylosis and intervertebral disc (IVD) degeneration are the most common cause for compression of the spinal cord and/or its roots. Total IVD arthroplasty, as a modern alternative to surgical treatment of IVD degeneration, is gaining popularity in many neurosurgical clinics around the world. Aim - the study aim was to conduct a multicenter analysis of cervical spine arthroplasty with an IVD prosthesis M6-C ('Spinal Kinetics', USA). MATERIAL AND METHODS: The study included 112 patients (77 males and 35 females)...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/29074465/comparison-of-three-dimensional-helical-axes-of-the-cervical-spine-between-in-vitro-and-in-vivo-testing
#19
René Jonas, Robert Demmelmaier, Steffen P Hacker, Hans-Joachim Wilke
BACKGROUND CONTEXT: The range of motion is a well-accepted parameter for the assessment and evaluation of cervical motion. However, more qualitative data of the kinematics of the cervical spine is needed for the development and success of cervical disc arthroplasty [1]. PURPOSE: The aim of this study was to provide basic information about helical axes of human cervical spine under in vitro conditions. Furthermore it should clarify whether the three-dimensional helical axes of cervical motion gained from in vitro experiments are in agreement with those gained from in vivo experiments and therefore to prove its reliability...
October 23, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29019902/in-vitro-biomechanical-comparison-after-fixed-and-mobile-core-artificial-cervical-disc-replacement-versus-fusion
#20
COMPARATIVE STUDY
Jigang Lou, Yuanchao Li, Beiyu Wang, Yang Meng, Tingkui Wu, Hao Liu
In vitro biomechanical analysis after cervical disc replacement (CDR) with a novel artificial disc prosthesis (mobile core) was conducted and compared with the intact model, simulated fusion, and CDR with a fixed-core prosthesis. The purpose of this experimental study was to analyze the biomechanical changes after CDR with a novel prosthesis and the differences between fixed- and mobile-core prostheses.Six human cadaveric C2-C7 specimens were biomechanically tested sequentially in 4 different spinal models: intact specimens, simulated fusion, CDR with a fixed-core prosthesis (Discover, DePuy), and CDR with a mobile-core prosthesis (Pretic-I, Trauson)...
October 2017: Medicine (Baltimore)
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