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Neutrophil/lymphocyte ratio

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https://www.readbyqxmd.com/read/29786814/predictive-value-of-preoperative-neutrophil-to-lymphocyte-ratio-while-detecting-bowel-resection-in-hernia-with-intestinal-incarceration
#1
Hande Köksal, Derviş Ateş, Emet Ebru Nazik, İlknur Küçükosmanoğlu, Serap Melek Doğan, Osman Doğru
BACKGROUND: The aim of this study was to evaluate the relationship between preoperative hematological inflammatory markers of the patients who underwent a surgery for incarcerated hernia and intestinal resection requirement. METHODS: The data of 102 patients who underwent a surgery for incarcerated hernia were retrospectively evaluated. Whole blood cell counts were preoperatively measured, and operation types and pathology results were recorded. The patients with intestinal resections were compared with those without any resection in terms of leukocyte number, neutrophil rate, red cell distribution width (RDW), platelet distribution width, neutrophil-to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and mean platelet volume (MPV)...
May 2018: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29782839/different-regulation-of-cortisol-and-corticosterone-in-the-subterranean-rodent-ctenomys-talarum-responses-to-dexamethasone-angiotensin-ii-potassium-and-diet
#2
Federico Vera, C Daniel Antenucci, Roxana R Zenuto
When harmful environmental stimuli occur, glucocorticoids (GCs), cortisol and corticosterone are currently used to evaluate stress status in vertebrates, since their secretions are primarily associated to an increased activity of the hypothalamic-pituitary-adrenal (HPA) axis. To advance in our comprehension about GCs regulation, we evaluated the subterranean rodent Ctenomys talarum to assess cortisol and corticosterone response to (1) the negative feedback of the HPA axis using the dexamethasone (DEX) suppression test, (2) angiotensin II (Ang II), (3) potassium (K+ ) intake, and (4) different diets (vegetables, grasses, acute fasting)...
May 18, 2018: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/29782381/high-baseline-neutrophil-to-lymphocyte-ratio-predicts-worse-outcome-in-patients-with-metastatic-braf-positive-melanoma-treated-with-braf-and-mek-inhibitors
#3
Paweł Teterycz, Paulina Jagodzińska-Mucha, Bożena Cybulska-Stopa, Anna Mariuk-Jarema, Katarzyna Kozak, Hanna Koseła-Paterczyk, Anna M Czarnecka, Marcin Rajczykowski, Robert Dziura, Łukasz Galus, Jacek Mackiewicz, Tomasz Świtaj, Anna Klimczak, Slawomir Falkowski, Rafał Suwiński, Marek Ziobro, Iwona Ługowska, Piotr Rutkowski
Neutrophil-to-lymphocyte ratio (NLR) has been shown to be prognostic in several solid malignancies. There are limited data regarding its value during novel therapies in patients with melanoma. The aim of the study was to assess the practical utility of this ratio in patients with BRAF-mutant melanoma treated with a combination of BRAF and MEK inhibitors (BRAFi/MEKi). We included 215 patients with inoperable or metastatic melanoma who underwent BRAFi/MEKi treatment between October 2015 and June 2017. Baseline NLR and other complete blood count-derived inflammatory markers were tested for association with overall survival and progression-free survival in univariate and multivariate models...
May 18, 2018: Melanoma Research
https://www.readbyqxmd.com/read/29781285/response-to-the-letter-to-the-editor-the-relationship-between-neutrophil-lymphocyte-ratio-and-in-stent-restenosis
#4
Zhihui Chang, Jiahe Zheng, Zhaoyu Liu, Qiyong Guo
No abstract text is available yet for this article.
January 1, 2018: Angiology
https://www.readbyqxmd.com/read/29780782/combination-of-clinical-and-laboratory-characteristics-may-serve-as-a-potential-diagnostic-marker-for-torsion-on-mature-cystic-teratomas
#5
Ji Yun Lee, Whan Shin, Jeong Sook Kim, Joo Hyun Park, SiHyun Cho
Objective: The objective of this study was to evaluate clinical and laboratory characteristics of torsion on mature cystic teratomas (MCTs). In addition, we examined whether these factors could be helpful in diagnosing MCT torsion. Methods: A retrospective medical record review was conducted for 384 patients who had undergone surgery and histologically verified ovarian MCTs at single university hospital between July 2006 and May 2017. Patients with or without torsion groups were compared with respect to clinical presentation, laboratory findings and surgical course...
May 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29779969/increased-malondialdehyde-vs-reduced-sirtuin-1-in-relation-with-adiposity-atherogenicity-and-hematological-indices-in-metabolic-syndrome-patients-with-and-without-prediabetes
#6
Samar Abu Rkhaya, Nailya Bulatova, Violet Kasabri, Randa Naffa, Reema Alquoqa
BACKGROUND: Sirtuin 1 (SIRT 1) and malondialdehyde (MDA) were implicated in metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) pathophysiology. AIMS AND METHODS: This cross-sectional study aimed to investigate both SIRT 1 and MDA in 30 lean healthy control, 31 normoglycemic MetS subjects and 30 MetS-Pre/T2DM drug naïve. C orrelation studies were established for both biomarkers with adiposity indices [conicity index (CI), waist circumference (WC), weight-to-height (WHtR) ratio, weight-to-hip (WHR) ratio, hip circumference (HC), and body adiposity index (BAI)], hematological indices [red cell distribution width (RDW), mean platelet volume (MPV), platelet-to-lymphcyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR)] and atherogenicity indices (atherogenicity index of plasma (AIP = log10 TG/HDL-C ratio), TC/HDL-C and LDL-C/HDL-C ratios]...
May 15, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29776362/apolipoprotein-b-apolipoprotein-a1-ratio-and-mortality-among-incident-peritoneal-dialysis-patients
#7
Xiaojiang Zhan, Yanbing Chen, Caixia Yan, Siyi Liu, Lijuan Deng, Yuting Yang, Panlin Qiu, Dan Pan, Bingxiang Zeng, Qinkai Chen
BACKGROUND: To investigate the association between the ratio of apolipoprotein B (apo B) / apolipoprotein A1 (apo A1) with all-cause mortality and cardiovascular events in peritoneal dialysis (PD) patients. METHODS: Eight hundred and sixty incident PD patients were enrolled from November 1, 2005, to February 28, 2017, and followed until May 31, 2017. Outcomes were all-cause mortality and cardiovascular events. Associations between the apo B/apo A1 ratio with all-cause mortality and cardiovascular events were evaluated using multivariable-adjusted Cox models...
May 17, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29774997/-the-significance-of-lymphocyte-to-monocyte-ratio-in-peripheral-blood-of-patients-with-benign-and-malignant-laryngeal-lesions
#8
D Q Wu, X S Huang
Objective: The aim of this study is to investigate the value of preoperative peripheral blood lymphocyte to monocyte ratio (LMR) in differentiating laryngeal squamous cell carcinoma (LSCC), laryngeal precancerous lesions (LPL) and laryngeal benign lesions (LBL). Method: Four hundred and five cases of laryngeal lesions diagnosed by pathology (154 cases of LSCC, 83 cases of LPL and 168 cases of LBL) were collected. LSCC group was further divided into T1 group, T2 group and T3-4 group based on T stage. The levels of neutrophils, lymphocytes, monocytes, hemoglobin, platelet and other blood indexes were measured, as well as compared the LMR, neutrophil to lymphocyte ratio (NLR) and other parameters in each group...
June 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29774108/prognostic-and-diagnostic-impact-of-fibrinogen-neutrophil-to-lymphocyte-ratio-and-platelet-to-lymphocyte-ratio-on-thymic-epithelial-tumors-outcome
#9
Stefan Janik, Thomas Raunegger, Philipp Hacker, Bahil Ghanim, Elisa Einwallner, Leonhard Müllauer, Ana-Iris Schiefer, Julia Moser, Walter Klepetko, Hendrik Jan Ankersmit, Bernhard Moser
Background: Peripheral blood-derived inflammation-based markers, such as Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Fibrinogen have been identified as prognostic markers in various solid malignancies. Here we aimed to investigate the prognostic and diagnostic impact of NLR, PLR, and Fibrinogen in patients with thymic epithelial tumors (TETs). Results: Pretreatment Fibrinogen serum concentrations, NLRs and PLRs were highest in patients with TCs and advanced tumor stages...
April 24, 2018: Oncotarget
https://www.readbyqxmd.com/read/29773957/perioperative-predictors-of-delirium-and-incidence-factors-in-adult-patients-post-cardiac-surgery
#10
Stavros Theologou, Konstantinos Giakoumidakis, Christos Charitos
Background: Delirium is a quite common complication in adult patients post-cardiac surgery. The purpose of our study was to identify perioperative characteristics and also focus on incidence factors that could predict delirium in the cardiac surgery intensive care unit (CICU) postoperatively. Methods: We conducted a prospective study of 179 consecutive patients, who underwent open-heart surgical operation and were admitted to the CICU of a general tertiary hospital in Athens, Greece...
2018: Pragmatic and Observational Research
https://www.readbyqxmd.com/read/29773759/neutrophil-lymphocyte-ratio-and-creatinine-reduction-ratio-predict-good-early-graft-function-among-adult-cadaveric-donor-renal-transplant-recipients-single-institution-series
#11
Piotr Hogendorf, Anna Suska, Aleksander Skulimowski, Joanna Rut, Monika Grochowska, Aleksandra Wencel, Filip Dziwisz, Michał Nowicki, Dariusz Szymański, Grażyna Poznańska, Adam Durczyński, Janusz Strzelczyk
Background Delayed graft function (DGF) is a common complication following kidney transplantation and is associated with ischemia-reperfusion injury (IRI). Lymphocytes contribute to the pathogenesis of IRI and ischemia-reperfusion related delayed graft function Materials and Methods 135 Caucasian patients received a kidney graft from deceased heart-beating organ donors. We divided patients into 2 groups- patients with the eGFR>=30 on the 21st day post-transplantation (n=36) and patients with the eGFR<30 on the 21st day post-transplantation (n=99) to assess kidney graft function...
April 30, 2018: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/29768976/predictors-of-intravenous-immunoglobulin-resistance-and-coronary-artery-aneurysm-in-patients-with-kawasaki-disease
#12
Nattika Chantasiriwan, Suchaya Silvilairat, Krit Makonkawkeyoon, Yupada Pongprot, Rekwan Sittiwangkul
BACKGROUND: Patients with Kawasaki disease (KD) who have intravenous immunoglobulin (IVIG) resistance are at increased risk for development of coronary artery abnormalities. Although in Japan several risk scoring systems are able to predict patients with IVIG-resistant (KD), they do not accurately predict non-responders in other regions. AIM: The objectives of this study were to determine the predictors of IVIG resistance and coronary artery aneurysm (CAA) and to develop risk scoring systems for predicting IVIG-resistant KD in the Thai population...
May 17, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/29768325/is-nucleate-cell-count-and-neutrophil-to-lymphocyte-ratio-related-to-patients-with-audiographically-distinct-sudden-sensorineural-hearing-loss
#13
Yuanyuan Sun, Liang Xia, Hui Wang, Zhengnong Chen, Yaqin Wu, Bin Chen, Haibo Shi, Yanmei Feng, Shankai Yin
The aim of this study was to investigate the possible relationships between sudden sensorineural hearing loss (SSNHL) patients with distinct audiographic data and nucleate cell count and neutrophil to lymphocyte ratio (NLR).SSNHL patients differed in audiographic curves were included, 40 with low-frequency SSNHL (LF-SSNHL), 33 with high-frequency SSNHL (HF-SSNHL), 36 with all-frequency SSNHL (AF-SSNHL), 34 with total-deafness SSNHL (TD-SSNHL), and 31 age- and sex-matched healthy controls. Peripheral venous blood samples were collected and nucleate cell such as white blood cell (WBC), neutrophil and lymphocyte, and NLR were measured...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29768257/systemic-immune-inflammation-index-sii-is-useful-to-predict-survival-outcomes-in-patients-after-liver-transplantation-for-hepatocellular-carcinoma-within-hangzhou-criteria
#14
Hongyuan Fu, Jun Zheng, Jianye Cai, Kaining Zeng, Jia Yao, Liang Chen, Hui Li, Jiebin Zhang, Yingcai Zhang, Hui Zhao, Yang Yang
BACKGROUND: There is growing evidence that the systemic immune-inflammation index (SII), a novel prognostic biomarker based on peripheral lymphocyte, neutrophil, and platelet counts, is associated with poor prognosis for several tumors. However, the prognostic value of SII in patients with hepatocellular carcinoma (HCC) who undergo liver transplantation (LT) remains unclear. The aim of this study was to determine the correlation between SII and prognosis in these patients. METHODS: This retrospective study involved 150 patients with HCC who underwent LT within the Hangzhou criteria...
May 11, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29767470/early-increase-of-neutrophil-to-lymphocyte-ratio-predicts-30-day-mortality-in-patients-with-spontaneous-intracerebral-hemorrhage
#15
Fei Wang, Feng Xu, Ye Quan, Li Wang, Jian-Jun Xia, Ting-Ting Jiang, Li-Juan Shen, Wen-Hui Kang, Yong Ding, Li-Xia Mei, Xue-Feng Ju, Shan-You Hu, Xiao Wu
AIMS: To examine whether early rise of neutrophil-to-lymphocyte ratio (NLR) after patient hospitalization correlates with 30-day mortality in patients with spontaneous intracerebral hemorrhage (ICH). METHODS: This retrospective study included all patients receiving treatment for spontaneous ICH between January 2015 and September 2016 at the Jiading District Central Hospital Affiliated Shanghai University of Medicine & Health Sciences in Shanghai, China. NLR was determined at admission (T1), at 24-48 hours (T2) and 5-7 days (T3)...
May 16, 2018: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/29766932/prognostic-value-of-cerebrospinal-fluid-lactate-in-meningitis-in-postoperative-neurosurgical-patients
#16
A S Sumanth Kumar, Barada Prasad Sahu, Ashish Kumar
Objective: To evaluate the prognostic usefulness of cerebrospinal fluid (CSF) lactate in postoperative bacterial meningitis (POBM) and to establish the optimal CSF lactate cut-off values in our population to identify POBM in neurosurgical patients. Patients and Methods: A prospective study of postoperative neurosurgical patients with presumed and established bacterial meningitis in the Department of Neurosurgery, NIMS, Hyderabad, India, from September 2012 to December 2014...
May 2018: Neurology India
https://www.readbyqxmd.com/read/29766456/prognostic-role-for-the-derived-neutrophil-to-lymphocyte-ratio-in-early-breast-cancer-a-geicam-9906-substudy
#17
A J Templeton, Á Rodríguez-Lescure, A Ruíz, E Alba, L Calvo, M Ruíz-Borrego, A Santaballa, C A Rodríguez, C Crespo, M Ramos, J M Gracia-Marco, A Lluch, I Álvarez, M I Casas, M Sánchez-Aragó, R Caballero, E Carrasco, E Amir, M Martin, A Ocaña
PURPOSE: Elevated markers of host inflammation, a hallmark of cancer, have been associated with worse outcomes in several solid tumors. Here, we explore the prognostic role of the derived neutrophil-to-lymphocyte ratio (dNLR), across different tumor subtypes, in patients with early breast cancer. PATIENTS AND METHODS: This was a retrospective analysis of 1246 patients with lymph node-positive, operable early breast cancer enrolled in the GEICAM/9906 trial, a multicenter randomized phase 3 study evaluating adjuvant chemotherapy...
May 15, 2018: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29765248/preoperative-neutrophil-to-lymphocyte-ratio-as-a-prognostic-predictor-after-curative-intent-surgery-for-hepatocellular-carcinoma-experience-from-a-developing-country
#18
Danijel Galun, Aleksandar Bogdanovic, Jelena Djokic Kovac, Predrag Bulajic, Zlatibor Loncar, Marinko Zuvela
Purpose: The aim of the study was to evaluate a prognostic value of preoperative neutrophil-to-lymphocyte ratio (NLR) on long-term survival of cirrhotic and noncirrhotic hepatocellular cancer (HCC) patients managed by a curative-intent liver surgery in a developing country. Patients and methods: During the study period between November 1, 2001, and December 31, 2012, 109 patients underwent potentially curative hepatectomy for HCC. Data were retrospectively reviewed from the prospectively collected database...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29763889/neutrophil-lymphocyte-ratio-predicts-functional-and-safety-outcomes-after-endovascular-treatment-for-acute-ischemic-stroke
#19
Zhenhui Duan, Huaiming Wang, Zhen Wang, Yonggang Hao, Wenjie Zi, Dong Yang, Zhiming Zhou, Wenhua Liu, Min Lin, Zhonghua Shi, Penghua Lv, Yue Wan, Gelin Xu, Yunyun Xiong, Wusheng Zhu, Xinfeng Liu
BACKGROUND AND OBJECTIVE: Endovascular treatment (EVT) is proven to be safe and effective for treating acute large vessel occlusion stroke (LVOS). The neutrophil-lymphocyte ratio (NLR) reflects systemic inflammation, which plays an important role in the process of treating ischemic stroke. This study aims to explore the relationship between NLR and the clinical outcomes of LVOS patients undergoing EVT. METHODS: Patients were selected from the EVT for acUte Anterior circuLation (ACTUAL) ischemic stroke registry...
May 15, 2018: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29761858/predictive-impact-of-the-inflammation-based-indices-in-colorectal-cancer-patients-with-adjuvant-chemotherapy
#20
Yong Tao, Lei Ding, Guan Gen Yang, Jian Ming Qiu, Dong Wang, Hongtao Wang, Chao Fu
Increasing evidences reported that cancer-triggered inflammation was associated with survival prognosis from colorectal cancer (CRC). However, the comprehensive effects of inflammatory-based coNLR-PLR that combines neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) rarely remain to be determined during chemotherapy. We retrospectively analyzed clinical data and baseline laboratory parameters from 153 colorectal cancer patients who underwent palliative adjuvant chemotherapy between January 2009 to January 2012...
May 15, 2018: Cancer Medicine
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