keyword
MENU ▼
Read by QxMD icon Read
search

Dry eye disease

keyword
https://www.readbyqxmd.com/read/28822028/effect-of-diquafosol-tetrasodium-3-on-the-conjunctival-surface-and-clinical-findings-after-cataract-surgery-in-patients-with-dry-eye
#1
Lian Cui, Ying Li, Hyo Seok Lee, Jee Myung Yang, Won Choi, Kyung Chul Yoon
PURPOSE: To investigate the effects of diquafosol tetrasodium (DT) 3% on conjunctival impression cytologic findings in addition to clinical symptoms and signs after cataract surgery in patients with preexisting dry eye disease (DED). METHODS: Ninety-four eyes of 94 patients with DED who underwent uneventful cataract surgery were included. In total, 50 patients were treated with DT 3% (group A), while 44 patients were treated with sodium hyaluronate 0.1% (group B) postoperatively, along with topical antibiotics and steroids...
August 18, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28821553/epidemiology-of-discordance-between-symptoms-and-signs-of-dry-eye
#2
Erin S Ong, Elizabeth R Felix, Roy C Levitt, William J Feuer, Constantine D Sarantopoulos, Anat Galor
BACKGROUND/AIMS: The frequent lack of association between dry eye (DE) symptoms and signs leads to challenges in diagnosing and assessing the disease. METHODS: Participants underwent ocular surface examinations to evaluate signs of disease and completed questionnaires to assess ocular symptoms, psychological status and medication use. To assess nociceptive system integrity, quantitative sensory testing (QST), including vibratory and thermal threshold measures and temporal summation of pain were obtained at the forearm and forehead...
August 18, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28814411/local-synthesis-of-sex-hormones-are-there-consequences-for-the-ocular-surface-and-dry-eye
#3
REVIEW
Emma J Gibson, Fiona Stapleton, James S Wolffsohn, Blanka Golebiowski
Sex hormones are associated with the physiology and pathophysiology of almost all organs in the body, as well as most diseases. Interest in the associations between sex hormones and ocular tissues has increased in recent years. Androgens may have a positive effect on dry eye, whereas the effects of oestrogen on ocular conditions remain unclear. Intracrinology, the local synthesis and metabolism of hormones that is unique to humans, is of relevance to the eye and may help to explain why studies of the relationship between oestrogens and dry eye signs and symptoms are inconclusive...
August 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28811095/can-the-optimum-artificial-tear-treatment-for-dry-eye-disease-be-predicted-from-presenting-signs-and-symptoms
#4
Laika Essa, Deborah Laughton, James S Wolffsohn
PURPOSE: To assess dry eye treatment with four preservative-free dry eye artificial tear treatments to facilitate evidence-based prescribing. METHODS: A randomised, single masked crossover trial of Clinitas Soothe, Hyabak, Tears Again and TheraTears artificial tears was conducted on 50 symptomatic dry eye patients, aged 60.8±14.2years. At baseline and after trialling each treatment for 4 weeks, signs and symptoms were assessed using the Ocular Surface Disease Index (OSDI), non-invasive tear break-up time, fluorescein tear break-up time, tear meniscus height (TMH), Phenol Red test, lid-parallel conjunctival folds (LIPCOF), ocular surface staining, and lipid layer grading and osmolarity (baseline visit only)...
August 12, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28805710/analysis-of-the-pathogenic-factors-and-management-of-dry-eye-in-ocular-surface-disorders
#5
REVIEW
Marcella Nebbioso, Paola Del Regno, Magda Gharbiya, Marta Sacchetti, Rocco Plateroti, Alessandro Lambiase
The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin, the main risk factors are female gender and advanced age. Likewise, morphological changes in several glands and in the chemical composition of their secretions, such as proteins, mucins, lipidics, aqueous tears, and salinity, are highly relevant factors that maintain a steady ocular surface...
August 13, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28791607/treatment-of-dry-eye-disease-with-autologous-platelet-rich-plasma-a-prospective-interventional-non-randomized-study
#6
Jorge L Alio, Alejandra E Rodriguez, Renan Ferreira-Oliveira, Dominika Wróbel-Dudzińska, Ahmed A Abdelghany
INTRODUCTION: The objective of this study was to evaluate the use of autologous platelet-rich plasma (PRP) eye drops as monotherapy for the treatment of moderate to severe cases of dry eye disease. METHODS: Three hundred and sixty-eight patients with moderate to severe dry eye disease (DED) were included in this prospective case series. Subjects were classified as evaporative DED (EDED) or aqueous deficient DED (ADDED). Improvement of the DED subjective symptoms, corneal fluorescein staining (CFS), and corrected distance visual acuity (BCVA) were evaluated...
August 8, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28791064/validation-of-farsi-translation-of-the-ocular-surface-disease-index
#7
Farzad Pakdel, Mahmood Reza Gohari, Anis Sadat Jazayeri, Afsaneh Amani, Niloofar Pirmarzdashti, Hossein Aghaee
PURPOSE: To develop and validate a Farsi version of Ocular Surface Disease Index (OSDI) for the Iranian population. METHODS: This study was a translation and cross-cultural adaptation and validation of Farsi version of OSDI. Four bilingual (English-Persian) individual including three physicians and one native English teacher were asked to translate the original English OSDI questionnaire in Farsi. Following back and forth translation, integration and pilot check, the translation team came to consensus on translation...
July 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28791059/risk-factors-for-pterygium-in-ilam-province-iran
#8
Parviz Malekifar, Hamed Esfandiari, Nazanin Behnaz, Fatemeh Javadi, Sima Azish, Mohammad Ali Javadi, Masumeh Kalantarion
PURPOSE: To evaluate the risk factors for pterygium in the dry, high altitude province of Ilam, Iran. METHODS: The study included patients who presented to ophthalmology clinic. The patients were divided into two groups: 210 diagnosed with pterygium or pinguecula (unilateral or bilateral), and 210 healthy controls. Demographic variables, living environment, disease type, disease laterality, family history of pterygium as well as history of smoking, working outdoors, baking, welding, ocular conditions (trachoma keratopathy, glaucoma, refractive error, and dry eye), use of glasses, ultraviolet light exposure, and systemic conditions were collected from both groups and compared for risk assessment...
July 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28790801/intense-pulsed-light-for-evaporative-dry-eye-disease
#9
REVIEW
Steven J Dell
There is a clear association between dry eye disease (DED) and skin inflammatory diseases occurring in close proximity to the eyelids, such as facial skin rosacea. Intense pulsed light (IPL) is widely accepted as a treatment for skin rosacea. A number of recent studies demonstrated that, in patients suffering from meibomian gland dysfunction (MGD), IPL therapy also reduces signs and symptoms of DED. Despite these encouraging results, in the context of DED and MGD, the mechanisms of action of IPL are not well understood...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28790800/clinical-utility-of-cyclosporine-csa-ophthalmic-emulsion-0-05-for-symptomatic-relief-in-people-with-chronic-dry-eye-a-review-of-the-literature
#10
REVIEW
Michelle K Rhee, Francis S Mah
To review the literature on the efficacy of cyclosporine (CsA) ophthalmic emulsion 0.05% on symptomatic relief in chronic dry eye disease. There is consistent evidence of objective improvements in chronic dry eye disease (Schirmer score, corneal and interpalpebral dye staining, and tear breakup time) with CsA, but variable results with symptomatic improvement, possibly due to patient tolerance of CsA, similar comforting effect with artificial tears and CsA vehicle, and the inherent subjective nature of symptom monitoring and analysis...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28789979/conjunctival-subepithelial-fibrosis-and-meibomian-gland-atrophy-in-ocular-graft-versus-host-disease
#11
Yael Kusne, M'hamed Temkit, Nandita Khera, Dharmendra R Patel, Joanne F Shen
PURPOSE: Dry eye symptoms greatly impact patients' quality of life in ocular graft-versus-host disease (oGVHD). Various ocular surface changes have been reported in oGVHD, including meibomian gland atrophy (MGA) and clinical conjunctival scarring or subepithelial fibrosis (CSEF). The relationships between CSEF, MGA, and other ocular surface changes in oGVHD were examined. METHODS: Charts of 21 consecutive GVHD patients examined by a single ophthalmologist were retrospectively reviewed...
August 5, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28782783/poly-%C3%AE%C2%B5-caprolactone-nanocapsule-carriers-with-sustained-drug-release-single-dose-for-long-term-glaucoma-treatment
#12
Chih-Hung Lee, Yu-Jia Li, Chih-Ching Huang, Jui-Yang Lai
Glaucoma is an eye-related disease accompanied by highly elevated intraocular pressure (IOP), which causes damage to the optic nerve and results in vision loss and even blindness. Although the treatment of glaucoma with eye drops may reduce the IOP, eye drops have some limitations, such as poor patient compliance and short duration. To develop drug carriers that facilitate the sustained and long-term release of drugs for glaucoma therapy, we synthesized poly(ε-caprolactone) nanoparticles (PCL NPs) capable of loading pilocarpine, a widely used drug for the treatment of dry eye and glaucoma...
August 7, 2017: Nanoscale
https://www.readbyqxmd.com/read/28782089/the-role-of-lipids-in-corneal-diseases-and-dystrophies-a-systematic-review
#13
REVIEW
Tyler G Rowsey, Dimitrios Karamichos
Corneal diseases are an extensive cause of blindness worldwide and continue to persist as a challenging public health concern. Recently, various lipid-based therapies have been advocated for the modulation of corneal diseases; however, the number of studies is still very limited. Here we focus on developments and challenges on lipid-based therapies for dry eye disease, diabetic neuropathy, and Fuchs' endothelial corneal dystrophy. All three diseases are highly prevalent conditions and involve corneal stress and inflammation...
December 2017: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/28777385/efficacy-of-eyedrops-containing-cross-linked-hyaluronic-acid-and-coenzyme-q10-in-treating-patients-with-mild-to-moderate-dry-eye
#14
Elisa I Postorino, Laura Rania, Emanuela Aragona, Carmen Mannucci, Angela Alibrandi, Gioacchino Calapai, Domenico Puzzolo, Pasquale Aragona
PURPOSE: Dry eye disease (DED) is a common condition causing substantial burden. A randomized, controlled, single-masked study was performed in 40 patients with mild to moderate DED to evaluate the efficacy and safety of a collyrium based on crosslinked hyaluronic acid (XLHA) with coenzyme Q10 (CoQ10). METHODS: Enrolled subjects were divided into 2 groups: group A, treated with XLHA + CoQ10; and group B, treated with hyaluronic acid (HA). Eyedrops were administered 4 times daily for 3 months...
August 2, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28775329/transient-ingrowth-of-lymphatic-vessels-into-the-physiologically-avascular-cornea-regulates-corneal-edema-and-transparency
#15
Deniz Hos, Anne Bukowiecki, Jens Horstmann, Felix Bock, Franziska Bucher, Ludwig M Heindl, Sebastian Siebelmann, Philipp Steven, Reza Dana, Sabine A Eming, Claus Cursiefen
Lymphangiogenesis is essential for fluid homeostasis in vascularized tissues. In the normally avascular cornea, however, pathological lymphangiogenesis mediates diseases like corneal transplant rejection, dry eye disease, and allergy. So far, a physiological role for lymphangiogenesis in a primarily avascular site such as the cornea has not been described. Using a mouse model of perforating corneal injury that causes acute and severe fluid accumulation in the cornea, we show that lymphatics transiently and selectively invade the cornea and regulate the resolution of corneal edema...
August 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28771380/antioxidant-and-osmoprotecting-activity-of-taurine-in-dry-eye-models
#16
Claudio Bucolo, Annamaria Fidilio, Chiara Bianca Maria Platania, Federica Geraci, Francesca Lazzara, Filippo Drago
PURPOSE: To assess the protective effects of ophthalmic formulations based on taurine (TAU) and sodium hyaluronate (SH) in ocular surface. METHODS: Rabbit corneal epithelial cells [Statens Seruminstitut Rabbit Cornea (SIRC)] were subjected to oxidative stress (1 mM H2O2) and treated with the following formulations: 0.2% SH, 0.4% SH, 0.4% SH +0.5% TAU. Reactive oxygen species (ROS) were evaluated by commercial kit. Dry eye was induced by atropine sulfate and topical treatment was carried out with the following formulations: 0...
August 3, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28771187/herbal-supplement-in-a-buffer-for-dry-eye-syndrome-treatment
#17
Hung-Chang Chen, Zhi-Yu Chen, Tsung-Jen Wang, Victor J Drew, Ching-Li Tseng, Hsu-Wei Fang, Feng-Huei Lin
Dry eye syndrome (DES) is one of the most common types of ocular diseases. There is a major need to treat DES in a simple yet efficient way. Artificial tears (AT) are the most commonly used agents for treating DES, but are not very effective. Herbal extractions of ferulic acid (FA), an anti-oxidant agent, and kaempferol (KM), an anti-inflammatory reagent, were added to buffer solution (BS) to replace ATs for DES treatment. The cytotoxicity and anti-inflammatory effects were examined in vitro by co-culture with human corneal epithelial cells (HCECs) to obtain the optimal concentration of KM and FA for treating HCECs...
August 3, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28769593/resolution-of-pinguecula-related-dry-eye-disease-after-argon-laser-photocoagulation
#18
Pietro Emanuele Napoli, Raffaele Sanna, Claudio Iovino, Maurizio Fossarello
PURPOSE: To describe an unusual case of unilateral, chronic symptoms and signs of dry eye, and recurrent episodes of ocular irritation related to pinguecula, which were refractory to prior medical treatments, successfully treated with argon laser photocoagulation. METHODS: A 36-year-old man presented with an elevated yellowish mass on his conjunctiva in his left eye, which was associated with dry eye symptoms and general discomfort, such as "tightening sensation" and "stiffness"...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28759302/evaluation-of-clinical-efficacy-and-safety-of-a-novel-cyclosporin-a-nanoemulsion-in-the-treatment-of-dry-eye-syndrome
#19
Hyun Seung Kim, Tae-Im Kim, Jin Hyoung Kim, Kyung Chul Yoon, Joon Young Hyon, Ko Un Shin, Chul Young Choi
PURPOSE: Topical administration of the anti-inflammatory agent cyclosporin A (CsA) is recommended for long-term management of dry eye syndrome (DES), yet standard ophthalmic CsA preparations have been reported to be unstable. In this trial, the efficacy and safety of Clacier™ (based on a phase 3 study developed by Huons Co. Ltd.), a novel 0.05% CsA nanoemulsion formulation, are compared with those of the conventional Restasis(®) emulsion. METHODS: Patients with moderate-to-severe DES were randomly assigned to receive topical 0...
July 31, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28752695/changes-in-tear-volume-after-3-diquafosol-treatment-in-patients-with-dry-eye-syndrome-an-anterior-segment-spectral-domain-optical-coherence-tomography-study
#20
Kwan Bok Lee, Kyung Min Koh, Young A Kwon, Sang Wroul Song, Byoung Yeop Kim, Jae Lim Chung
PURPOSE: To evaluate changes in the tear meniscus area and tear meniscus height over time in patients with dry eye syndrome, using anterior segment spectral-domain optical coherence tomography after the instillation of 3% diquafosol ophthalmic solution. METHODS: Sixty eyes from 30 patients with mild to moderate dry eye syndrome were included. Tear meniscus images acquired by anterior segment spectral-domain optical coherence tomography were analyzed using National Institutes of Health's image-analysis software (ImageJ 1...
August 2017: Korean Journal of Ophthalmology: KJO
keyword
keyword
38375
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"