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https://www.readbyqxmd.com/read/28324848/is-level-of-prematurity-a-risk-plasticity-factor-at-three-years-of-age
#1
Kristin Hadfield, Fearghal O'Brien, Aaron Gerow
Children born preterm have poorer outcomes than children born full-term, but the caregiving environment can ameliorate some of these differences. Recent research has proposed that preterm birth may be a plasticity factor, leading to better outcomes for preterm than full-term infants in higher quality environments. This analysis uses data from two waves of an Irish study of children (at 9 months and 3 years of age, n=11,134 children) and their caregivers (n=11,132 mothers, n=9998 fathers) to investigate differences in how caregiving affects social, cognitive, and motor skills between full-term, late preterm, and very preterm children...
March 18, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28324760/trpv1-agonism-inhibits-endothelial-cell-inflammation-via-activation-of-enos-no-pathway
#2
Youping Wang, Lin Cui, Hui Xu, Suxiao Liu, Feiyun Zhu, Fengna Yan, Si Shen, Mingjun Zhu
BACKGROUND AND AIMS: Transient receptor potential vanilloid type 1 channel (TRPV1) is found to be expressed in endothelial cells (ECs) and activate endothelial nitric oxide synthase (eNOS). Recent studies implicate TRPV1 in attenuating inflammatory responses. However, the mechanisms underlying the beneficial effects remain unclear. In this study, we investigated whether TRPV1 suppresses inflammatory responses of ECs via eNOS/NO pathway. METHODS: Human umbilical vein endothelial cells (HUVECs) and renal microvascular endothelial cells (MVECs) isolated from deoxycorticosterone (DOCA)-salt hypertensive mice were cultured in the presence of capsaicin (CAP, a specific TRPV1 agonist) with or without the specific inhibitor of TRPV1, NOS, or Ca(2+)-dependent phosphatidylinositol 3-kinase (PI3K)/Akt pathway, before lipopolysaccharide (LPS) stimulation...
March 10, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28324700/attachment-predicts-cortisol-response-and-closeness-in-dyadic-social-interaction
#3
Sarah Ketay, Lindsey A Beck
The present study examined how the interplay of partners' attachment styles influences cortisol response, actual closeness, and desired closeness during friendship initiation. Participants provided salivary cortisol samples at four timepoints throughout either a high or low closeness task that facilitated high or low levels of self-disclosure with a potential friend (i.e., another same-sex participant). Levels of actual closeness and desired closeness following the task were measured via inclusion of other in the self...
March 7, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28324691/comparison-of-three-different-types-of-cilostazol-loaded-solid-dispersion-physicochemical-characterization-and-pharmacokinetics-in-rats
#4
Omer Mustapha, Kyung Soo Kim, Shumaila Shafique, Dong Shik Kim, Sung Giu Jin, Youn Gee Seo, Yu Seok Youn, Kyung Taek Oh, Chul Soon Yong, Jong Oh Kim, Han-Gon Choi
The aim of this research was to compare three different types of cilostazol-loaded solid dispersion system including solvent-evaporated, solvent-wetted and surface-attached solid dispersion. The effect of polymers and surfactants on the aqueous solubility of cilostazol was investigated, leading to the selection of polyvinylpyrrolidone (PVP) and sodium lauryl sulphate (SLS). Employing a spray-drying technique, numerous surface-attached, solvent-evaporated and solvent-wetted solid dispersions were prepared with various amounts PVP and SLS using water, 90% ethanol and acetone, respectively...
March 9, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28324690/e-coli-interactions-adhesion-and-transport-in-alumino-silica-clays
#5
Houzhen Wei, Guang Yang, Boya Wang, Runwei Li, Gang Chen, Zhenze Li
Bacterial adhesion and transport in the geological formation are controlled by their mutual complex interactions, which have been quantified by the traditional and extended Derjaguin-Landau-Verwey-Overbeek (DLVO) theory as well as direct atomic force microscopy (AFM) measurements. In this research, the DLVO forces calculated based on the independently determined bacterial and porous media surface thermodynamic properties were compared with those of AFM measurements. Although differences in the order of several magnitudes existed, forces obtained from both ways could explain the observations of E...
March 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28324644/synthesis-of-the-t-705-ribonucleoside-and-ribonucleotide-and-studies-on-the-chemical-stability
#6
Johanna Huchting, Matthias Winkler, Hiba Nasser, Chris Meier
T-705 (favipiravir) is a fluorinated hydroxypyrazine carboxamide that exhibits antiviral activities against a variety of RNA viruses. Due to the lack of potent agents to combat these infections caused by a large number of these high-impacting pathogens, huge emphasis has been put on the studies of T-705's antiviral properties and its mechanism of action. T-705 acts as a nucleobase analogue; hence, it is metabolized to the corresponding ribonucleoside triphosphate intracellularly. We herein report a reliable synthesis of T-705-ribonucleoside and its 5'-monophosphate...
March 21, 2017: ChemMedChem
https://www.readbyqxmd.com/read/28324629/electrospun-nerve-guide-scaffold-of-poly-%C3%AE%C2%B5-caprolactone-collagen-nano-bioglass-an-in-vitro-study-in-peripheral-nerve-tissue-engineering
#7
Forouzan Mohamadi, Somayeh Ebrahimi-Barough, Mohammad Reza Nourani, Mohammad Ali Derakhshan, Vahabodin Goodarzi, Mohammad Sadegh Nazockdast, Mehdi Farokhi, Roksana Tajerian, Reza Faridi Majidi, Jafar Ai
In among of various methods, nerve tissue engineering (NTE) is one of the applicable methods to reconstruct damaged nerve tissues. Electrospinning technique and biomaterials are often considered to fabricate fibrous tissue engineered conduits which have great similarity to the extracellular matrix on fiber structure. Polymer blending is one of the most effective methods for production of new materials with outstanding features. In this research, conduit structures as main part of the peripheral nerve regeneration based on polymer blend nanocomposites PCL/Collagen/NBG (poly (ε-caprolactone)/Collagen/nano bioglass) were manufactured by electrospinning technique...
March 21, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28324130/the-oblique-popliteal-ligament-an-anatomic-and-mri-investigation
#8
Mandy Hedderwick, Mark D Stringer, Liam McRedmond, Grant R Meikle, Stephanie J Woodley
PURPOSE: Despite being the largest ligament on the posterior aspect of the knee, relatively little is known about the normal morphology of the oblique popliteal ligament (OPL). The aim of this study was to investigate the detailed anatomy of the OPL in cadavers and healthy volunteers. METHODS: The posterior knee was investigated in 25 cadaver lower limbs (mean age 76 ± 9.5 years; 7 men) by dissection, histology, and serial plastination and in 14 healthy individuals (mean age 23 ± 3...
March 21, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28324064/bmp7-induces-uterine-receptivity-and-blastocyst-attachment
#9
Diana Monsivais, Caterina Clementi, Jia Peng, Paul T Fullerton, Renata Prunskaite-Hyyryläinen, Seppo Vainio, Martin M Matzuk
In women, the window of implantation is limited to a brief two- to three- day period characterized by optimal levels of circulating ovarian hormones and a receptive endometrium. Although the window of implantation is assumed to occur 8-10 days after ovulation in women, molecular markers of endometrial receptivity are necessary to determine optimal timing prior to embryo transfer. Previous studies showed that members of the bone morphogenetic protein (BMP) family are expressed in the uterus necessary for female fertility; however, the role of BMP7 during implantation and in late gestation is not known...
January 17, 2017: Endocrinology
https://www.readbyqxmd.com/read/28323542/organized-abuse-in-adulthood-survivor-and-professional-perspectives
#10
Michael Salter
This paper reports on the preliminary findings of a qualitative study of Australian women disclosing organized abuse in adulthood and the mental health professionals who treat them. Drawing on interviews with survivors and mental health professionals, the paper analyses the fraught relationship between mental health and physical safety for adults subject to organized abuse. The therapeutic progress of adult organized abuse victims can be disrupted by ongoing threats, stalking, and group violence, which in turn reinforces the dissociative responses and pathological attachments that render them vulnerable to revictimization...
February 23, 2017: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/28323432/electronic-structures-and-oh-induced-atmospheric-degradation-of-cf3nsf2-a-potential-green-dielectric-replacement-for-sf6
#11
Lin Cheng, Xiaojuan Yu, Kun Zhao, Hua Hou, Baoshan Wang
Electronic structures of Trifluoromethyl imionosulfur difluoride (CF3NSF2) and degradation mechanisms by hydroxyl radical have been investigated using density functional theory (M06-2X), the complete basis set quadratic CBS-Q, and the explicitly correlated coupled-cluster methods [CCSD(T)-F12]. The d-function augmented Correlation-consistent basis sets including triple- and quadruple- were employed for the sulfur-containing species. It was found that CF3NSF2 exists as two conformations connected by the internal rotation of CF3 around the central NS bond...
March 21, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28323412/temporary-single-cell-coating-for-bioprocessing-via-a-cationic-polymer
#12
Ricardo Da Conceicao Ribeiro, Deepali Pal, David Jamieson, Kenneth Samora Rankin, Matthew Benning, Kenneth W Dalgarno, Ana Marina Ferreira
Temporary single cell coating is a useful tool for cell processing, allowing manipulation of cells to prevent cell attachment and agglomeration, before re-establishing normal cell function. In this paper, a speckled coating method using a known polycation (poly-L-lysine, PLL) is described to induce cell surface electrostatic charges on three different cell types - two bone cancer cell lines and fibroblasts. The morphology of the PLL speckled coating on the cell surface, internalization and metabolization of the polymer, and prevention of cellular aggregations are reported...
March 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28319385/structural-and-electronic-properties-of-transition-metal-oxides-attached-to-a-single-walled-cnt-as-a-lithium-ion-battery-electrode-a-first-principles-study
#13
Liew Weng Tack, Mohd Asyadi Azam, Raja Noor Amalina Raja Seman
Single-walled carbon nanotubes (SWCNTs) and metal oxides (MOs), such as manganese (IV) oxide (MnO2), cobalt (II, III) oxide (Co3O4), and nickel (II) oxide (NiO) hybrid structures, have received great attention because of their promising application in lithium-ion batteries (LIBs). As electrode materials for LIBs, the structure of SWCNT/MOs provides high power density, good electrical conductivity, and excellent cyclic stability. In this work, first-principles calculations were used to investigate the structural and electronic properties of MOs attached to (5, 5) SWCNT and Li-ion adsorption to SWCNT/ metal oxide composites as electrode materials in LIBs...
March 20, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28319324/future-of-robotic-surgery-in-urology
#14
Jens J Rassweiler, Riccardo Autorino, Jan Klein, Alex Mottrie, Ali Serdar Goezen, Jens-Uwe Stolzenburg, Koon H Rha, Marc Schurr, Jihad Kaouk, Vipul Patel, Prokar Dasgupta, Evangelos Liatsikos
OBJECTIVES: To provide a comprehensive overview of the current status and future perspectives in the field of robotic systems for urologic surgery. MATERIALS AND METHODS: A non-systematic literature review was performed by using PubMed / Medline search electronic engines. Existing patents for robotic devices were researched using the Google search machine. Findings were critically analyzed also by taking into account personal experience of the authors. RESULTS: Relevant patents of the first generation of the da Vinci platform will expire in 2019...
March 20, 2017: BJU International
https://www.readbyqxmd.com/read/28319216/influence-of-implant-number-and-location-on-strain-around-an-implant-combined-with-force-transferred-to-the-palate-in-maxillary-overdentures
#15
Tsung-Chieh Yang, Yi-Chen Chen, Tong-Mei Wang, Li-Deh Lin
This study evaluated the effect of implant number and location on strain around the implant and force transferred to the palate in maxillary implant overdentures (IODs), including two locators attached bilaterally in the canine region (IOD 2), four locators attached bilaterally in the canine and premolar regions (IOD 4CP), four locators attached bilaterally in the canine and molar regions (IOD 4CM), and six locators attached bilaterally in the canine, premolar, and molar regions (IOD 6). As the implant number increased, strain around the implant regions increased, whereas force transferred to the palate decreased under loading...
March 20, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28319215/number-and-location-of-mini-implants-retaining-a-mandibular-overdenture-to-resist-lateral-forces-a-preliminary-in-vitro-study
#16
Kyozo Takagaki, Tomoya Gonda, Yoshinobu Maeda
PURPOSE: The aim of this study was to determine the optimal number and location of mini-implants retaining an overdenture to resist lateral forces. MATERIALS AND METHODS: A strain gauge was attached to a mini-implant and placed in an edentulous mandible model. The following different implant locations were evaluated: one mini-implant at the midline, two mini-implants in the lateral incisor regions, two mini-implants in the canine regions, and four mini-implants...
March 20, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28319214/fabrication-of-a-mandibular-implant-supported-overdenture-with-a-new-attachment-system-a-review-of-current-attachment-systems
#17
Karnik Shah, Burak Yilmaz, Edwin McGlumphy
Since their introduction, implant-retained overdentures have represented a feasible, economical, and highly successful treatment option for completely edentulous patients. Different attachment systems have been effectively used to retain these implant overdentures, and each system has advantages and disadvantages. Locator attachment (Zest Anchors) is one system that has been widely used by clinicians, particularly, for two-implant-supported situations. Recently, Zest Anchors developed a new locator-style abutment, Locator R-Tx...
March 20, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28319208/posterior-mandibular-ridge-resorption-associated-with-different-retentive-systems-for-overdentures-a-7-year-retrospective-preliminary-study
#18
Moustafa Abdou Elsyad, Shahinaz Sayed Mohamed, Ahmad Fathalla Shawky
PURPOSE: This retrospective study compared posterior mandibular residual ridge resorption with two different retentive mechanisms for overdentures after 7 years. MATERIALS AND METHODS: A convenience sample of 18 edentulous men was assigned to one of two equal groups. Two implants were placed in the mandibular canine areas for each patient using the conventional two-stage surgical protocol, and the implants were splinted with a round bar 3 months later. New mandibular overdentures were then connected to the bars with clips (clip-retained overdentures, CR group) or resilient liners (resilient liner-retained overdentures, RR group)...
March 20, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28319042/smartphone-application-for-mechanical-quality-assurance-of-medical-linear-accelerator
#19
Hwiyoung Kim, Hyunseok Lee, Jong In Park, Chang Heon Choi, So-Yeon Park, Hee Jung Kim, Young Suk Kim, Sung-Joon Ye
Mechanical quality assurance (QA) of medical linear accelerators consists of time consuming and human-error prone procedures. We developed a smartphone-application system for mechanical QA. The system consists of two smartphones; one attached to the gantry to obtain real-time information on mechanical parameters of medical linear accelerator, and the other to display the real-time information by bluetoothing the former. Motion sensors embedded in the smartphone were used to measure gantry and collimator rotations...
March 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28319038/fracture-toughness-enhancement-of-h-bn-monolayers-via-hydrogen-passivation-of-a-crack-edge
#20
Rajesh Kumar, Avinash Parashar
Molecular dynamics-based simulations were performed in conjunction with reactive force-field potential parameters to investigate the effect of crack-edge passivation via hydrogenation on the fracture properties of h-BN nanosheets. In semi-hydrogenated (H is attached to either B or N) and fully hydrogenated (H is attached to both B and N) crack-edge atoms, three hybridisation states-sp(2), sp(3) and sp(2) + sp(3)-were considered in the simulations. Significant improvement in the fracture toughness of h-BN nanosheets was predicted with semi- and fully hydrogenated crack-edge atoms...
March 20, 2017: Nanotechnology
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