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https://www.readbyqxmd.com/read/27899367/intake-of-key-micronutrients-and-food-groups-in-patients-with-late-stage-age-related-macular-degeneration-compared-with-age-sex-matched-controls
#1
Bamini Gopinath, Gerald Liew, Joanna Russell, Victoria Cosatto, George Burlutsky, Paul Mitchell
BACKGROUND: Knowledge of the risk factor profile of patients presenting with late-stage age-related macular degeneration (AMD) could help identify the most frequent modifiable AMD precursors among people who are referred for treatment. We aimed to assess dietary behaviours by comparing adjusted mean intakes of micronutrients and major food groups (fruits, vegetables, fish) among patients with AMD and a sample of age-sex-matched controls. METHODS: Cross-sectional analysis of 480 late AMD cases and 518 population-based age-sex-matched controls with no AMD signs...
November 29, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27867449/exploring-the-potential-of-indigenous-foods-to-address-hidden-hunger-nutritive-value-of-indigenous-foods-of-santhal-tribal-community-of-jharkhand-india
#2
Suparna Ghosh-Jerath, Archna Singh, Melina S Magsumbol, Preeti Kamboj, Gail Goldberg
Traditional foods of indigenous communities can be explored as a sustainable means of addressing undernutrition. Our study aimed at identifying indigenous foods of the Santhal tribal community of Godda district of Jharkhand, India, assessing their nutritive value, and appraising their potential role in addressing hidden hunger. A cross-sectional survey using qualitative methods like focus group discussions with women of childbearing age (15-49 years), adult males, and elderly people was conducted for food identification...
October 1, 2016: Journal of Hunger & Environmental Nutrition
https://www.readbyqxmd.com/read/27859376/microwave-drying-of-germinated-corn-and-its-effect-on-phytochemical-properties
#3
Oraporn Bualuang, Onwude Daniel Iroemeha, Kwanta Pracha
BACKGROUND: Drying is a preservation method that removes or reduces the moisture content of a product. This process could affect the nutritional properties of agricultural crops. Therefore, this research seeks to investigate the effect of microwave drying power (100-700 W) on drying rate, effective diffusivity, antioxidant value of beta-carotene content (BCC), total flavonoid content (TFC), total phenolic content (TPC), and the antioxidant capacity of sprouted corn, which can be applied as a rich antioxidant source...
November 17, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27855891/modulation-of-chemical-stability-and-in-vitro-bioaccessibility-of-beta-carotene-loaded-in-kappa-carrageenan-oil-in-gel-emulsions
#4
Christos Soukoulis, Maria Tsevdou, Christelle M Andre, Sébastien Cambier, Lina Yonekura, Petros S Taoukis, Lucien Hoffmann
In the present paper, ionotropically structured κ-carrageenan based oil-in-gel (o/g) emulsions were tested as potential carrier systems for the delivery of β-carotene. In situ ionic gelation was induced by Na(+), K(+) or Ca(2+) added at the level of 0.2-0.6% (w/w). All o/g emulsions exerted a true gel like behaviour with storage modulus (G') being reduced according to the order: K(+)>Ca(2+)>Na(+). Ionic gelation induced a moderate increase in the microscopically assessed lipid droplets radii. O/g emulsions containing monovalent ions exerted the highest β-carotene retention throughout isothermal storage particularly at high (37 and 55°C) temperatures...
April 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27837090/distinct-mechanisms-of-the-orange-protein-in-controlling-carotenoid-flux
#5
Noam Chayut, Hui Yuan, Shachar Ohali, Ayala Meir, Uzi Saar, Galil Tzuri, Yi Zheng, Michael Mazourek, Shimon Gepstein, Xiangjun Zhou, Vitaly Portnoy, Efraim Lewinsohn, Arthur A Schaffer, Nurit Katzir, Zhangjun Fei, Ralf Welsch, Li Li, Josef Burger, Yaakov Tadmor
Beta-carotene adds nutritious value and determines the color of many fruits including melon. In melon mesocarp, β-carotene accumulation is governed by the Orange gene (CmOr) 'golden' SNP through a yet to be discovered mechanism. In Arabidopsis, OR increases carotenoid levels by posttranscriptionally regulating phytoene synthase (PSY). Here we identified a CmOr nonsense mutation (Cmor-lowβ), which lowered fruit β-carotene levels with impaired chromoplast biogenesis. Cmor-lowβ exerted a minimal effect on PSY transcripts but dramatically decreased PSY protein levels and enzymatic activity, leading to reduced carotenoid metabolic flux and accumulation...
November 11, 2016: Plant Physiology
https://www.readbyqxmd.com/read/27823732/cancer-chemoprevention-by-dietary-phytochemicals-epidemiological-evidence
#6
REVIEW
Raúl Baena Ruiz, Pedro Salinas Hernández
BACKGROUND: In recent years, natural compounds called "phytochemicals", which are present in fruits, vegetables, and plants, have received special attention due to their potential to interfere with tumour formation and development. Many of these phytochemicals are being used in chemoprevention strategies. However, the scientific evidence regarding the modification of cancer risk continues to be debated. OBJECTIVE: The aim of this paper is to review the current scientific evidence and the most relevant epidemiological studies regarding the consumption or use of phytochemicals and their effects on the incidence of cancer...
December 2016: Maturitas
https://www.readbyqxmd.com/read/27822323/inhibitory-effect-of-actinidia-arguta-on-mutagenesis-inflammation-and-two-stage-mouse-skin-tumorigenesis
#7
Mari Nishimura, Yuma Okimasu, Naoko Miyake, Misako Tada, Ryoko Hida, Tomoe Negishi, Sakae Arimoto-Kobayashi
BACKGROUND: Actinidia arguta, known as sarunashi in Japan, is a vine tree native to east-Asia, including Japan, that produces small fruit rich in anthocyanins, catechins, vitamin C, chlorophyll, beta-carotene and other polyphenols. RESULTS: Our study revealed the inhibitory effect of the juice of A. arguta (arguta-juice) toward the mutagenicity of food-derived carcinogens and polycyclic aromatic hydrocarbons using the Ames test, and antioxidant activity of arguta-juice as determined using a free radical scavenging assay...
2016: Genes and Environment: the Official Journal of the Japanese Environmental Mutagen Society
https://www.readbyqxmd.com/read/27780487/vitamin-e-and-the-risk-of-pneumonia-using-the-i-2-statistic-to-quantify-heterogeneity-within-a-controlled-trial
#8
Harri Hemilä
Analyses in nutritional epidemiology usually assume a uniform effect of a nutrient. Previously, four subgroups of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study of Finnish male smokers aged 50-69 years were identified in which vitamin E supplementation either significantly increased or decreased the risk of pneumonia. The purpose of this present study was to quantify the level of true heterogeneity in the effect of vitamin E on pneumonia incidence using the I 2 statistic. The I 2 value estimates the percentage of total variation across studies that is explained by true differences in the treatment effect rather than by chance, with a range from 0 to 100 %...
October 26, 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27757026/vitamin-e-administration-may-decrease-the-incidence-of-pneumonia-in-elderly-males
#9
Harri Hemilä
BACKGROUND: Vitamin E has influenced the immune system in laboratory studies. Dozens of animal experiments have found that vitamin E offered protection against infections caused by viruses and bacteria. Previously, significant heterogeneity was found in the effect of vitamin E supplementation on pneumonia in humans. The aim of this study was to examine how the effect of vitamin E on pneumonia risk depends on age. METHODS: Secondary analysis of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention study in Finland, 1985-1993, was performed...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27696529/outdoor-cultivation-of-dunaliella-salina-ku-11-using-brine-and-saline-lake-water-with-race-way-ponds-in-northeastern-thailand
#10
Zhe Wu, Wipawee Dejtisakdi, Prasart Kermanee, Chunhong Ma, Wallop Arirob, Ramaraj Sathasivam, Niran Juntawong
To evaluate the potential for algal biotechnology to replace traditional agriculture in northeastern Thailand, an open race-way cultivation system was developed to produce biomass and beta-carotene. Dunaliella salina KU 11 isolated from local saline soil was cultured in open race-way tanks using brine and saline lake water. Grown in modified Johnson's medium (with 2-3.5 M NaCl), the algae reached a maximum cell density on the fourth day (1.8×10(6) cells mL(-1) ). Increasing KNO3 and NaHCO3 from 0.5 and 0.043 g L(-1) to 1 and 2...
October 3, 2016: Biotechnology and Applied Biochemistry
https://www.readbyqxmd.com/read/27686856/tunisian-tomato-by-products-as-a-potential-source-of-natural-bioactive-compounds
#11
S Gharbi, G Renda, L La Barbera, M Amri, C M Messina, A Santulli
Consumption of tomato and tomato products is positively related to the reduction in cardiovascular disease and several types of cancer, thanks to the presence of natural compounds, such as antioxidants. Peels and seeds fractions of tomato, collected after industrial processing in Tunisian industries, were analysed for nutritional and antioxidants composition in perspective of its utilisation. Proximate composition, fatty acids profile, carotenoids, such as lycopene and beta-carotene, polyphenols contents, demonstrated the good potential of these residual products as a source of natural compounds, useful for food and nutraceuticals applications...
August 10, 2016: Natural Product Research
https://www.readbyqxmd.com/read/27673117/poster-366-post-surgical-rehabilitation-of-traumatic-sciatic-nerve-injury-enhanced-by-supplemental-beta-carotene-and-b-12
#12
Thiago Queiroz
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27667329/effects-of-a-japan-diet-intake-program-on-metabolic-parameters-in-middle-aged-men-a-pilot-study
#13
Chizuko Maruyama, Rena Nakano, Mitsuha Shima, Asumi Mae, Yuri Shijo, Eri Nakamura, Yuuna Okabe, Sunmi Park, Noriko Kameyama, Satomi Hirai, Mamoru Nakanishi, Kagehiro Uchida, Hiroshi Nishiyama
AIM: We conducted a pilot study to clarify the effects of the Japan Diet nutritional education program on metabolic risk factors for atherosclerotic cardiovascular disease in middle-aged men who were brought up in the westernized dietary environment of modern Japan. METHODS: Thirty-three men, 30-49 years of age, attended a nutrition education class to learn food items and recommended volumes comprising the Japan Diet (more fish, soybeans and soy products, vegetables, seaweed, mushrooms and unrefined cereals, and less animal fat, meat and poultry with fat, sweets, desserts and snacks, and alcoholic drinks), and were encouraged to consume the Japan Diet for 6 weeks...
September 21, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27629436/ascorbic-acid-and-beta-carotene-reduce-stress-induced-oxidative-organ-damage-in-rats
#14
M Esrefoglu, A Akinci, E Taslidere, H Elbe, A Cetin, B Ates
Antioxidants are potential therapeutic agents for reducing stress-induced organ damage. We investigated the effects of ascorbic acid and β-carotene on oxidative stress-induced cerebral, cerebellar, cardiac and hepatic damage using microscopy and biochemistry. Male Wistar albino rats were divided into five groups: untreated control, stressed, stressed + saline, stressed + ascorbic acid and stressed + β-carotene. The rats in the stressed groups were subjected to starvation, immobilization and cold. The histopathological damage scores for the stressed and stressed + saline groups were higher than those of the control group for all organs examined...
October 2016: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/27605086/p53-and-ki67-as-biomarkers-in-determining-response-to-chemoprevention-for-oral-leukoplakia
#15
Toru Nagao, Saman Warnakulasuriya, Hidenori Sakuma, Satoru Miyabe, Shogo Hasegawa, Junichiro Machida, Koji Suzuki, Hideo Fukano, Kazuo Shimozato, Shuji Hashimoto
BACKGROUND: We performed a randomized controlled chemoprevention trial of oral leukoplakia by administrating a low dose of beta-carotene and vitamin C supplements. 17% of subjects in the experimental arm (4/23) demonstrated clinical remission (complete or partial response) at completion of the trial. The objective of this study was to determine whether baseline expression of p53 and ki67 demonstrated any differences between those responding or not responding to our intervention. A secondary objective was to elucidate any relationship between dietary factors and clinical responses...
September 8, 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/27601851/antioxidant-and-anti-inflammatory-properties-of-algerian-thymelaea-microphylla-coss-and-dur-extracts
#16
Khadidja Dehimi, Antonio Speciale, Antonina Saija, Saliha Dahamna, Roberto Raciti, Francesco Cimino, Mariateresa Cristani
BACKGROUND: Thymelaea microphylla Coss. et Dur. (Thymelaeaceae) (TM) is a rare medicinal plant endemic to Algeria. Leaves decoction is used in folk medicine for anticancer, anti-inflammatory, and antidiabetic properties. OBJECTIVE: Herein, the antioxidant and anti-inflammatory properties of different extracts from leaves and flowers of Algerian TM were evaluated. MATERIALS AND METHODS: The study was carried out by in vitro cell-free assays (antioxidant/radical properties), ex vivo experiments (inhibition of prostaglandin E2 and thromboxane B2 release in human whole blood) and in vitro experiments on cell systems (cytotoxicity on peripheral blood mononuclear cells, and protective effects on human vein endothelial cells exposed to TNF-α)...
July 2016: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/27595636/associations-between-micronutrient-intakes-and-gut-microbiota-in-a-group-of-adults-with-cystic-fibrosis
#17
Li Li, Lutz Krause, Shawn Somerset
BACKGROUND: Cystic fibrosis (CF) involves chronic inflammation and oxidative stress affecting mainly the respiratory and digestive systems. Survival rates for CF have improved with advances in treatment including nutritional interventions such as micronutrient supplementation. Diet can modulate gut microbiota in the general population with consequences on local and systemic immunity, and inflammation. The gut microbiota appears disrupted and may associate with pulmonary status in CF. This study investigated associations between micronutrient intakes and gut microbiota variations in a group of adults with CF...
August 27, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27546575/plumage-genes-and-little-else-distinguish-the-genomes-of-hybridizing-warblers
#18
David P L Toews, Scott A Taylor, Rachel Vallender, Alan Brelsford, Bronwyn G Butcher, Philipp W Messer, Irby J Lovette
When related taxa hybridize extensively, their genomes may become increasingly homogenized over time. This mixing via hybridization creates conservation challenges when it reduces genetic or phenotypic diversity and when it endangers previously distinct species via genetic swamping [1]. However, hybridization also facilitates admixture mapping of traits that distinguish each species and the associated genes that maintain distinctiveness despite ongoing gene flow [2]. We address these dual aspects of hybridization in the golden-winged/blue-winged warbler complex, two phenotypically divergent warblers that are indistinguishable using traditional molecular markers and that draw substantial conservation attention [3-5]...
September 12, 2016: Current Biology: CB
https://www.readbyqxmd.com/read/27534643/prospective-study-of-serum-cysteine-and-cysteinylglycine-and-cancer-of-the-head-and-neck-esophagus-and-stomach-in-a-cohort-of-male-smokers
#19
Eugenia H Miranti, Neal D Freedman, Stephanie J Weinstein, Christian C Abnet, Jacob Selhub, Gwen Murphy, Lena Diaw, Satu Männistö, Philip R Taylor, Demetrius Albanes, Rachael Z Stolzenberg-Solomon
BACKGROUND: The nonessential amino acid cysteine is known to be involved in many antioxidant and anticarcinogenic pathways. Cysteinylglycine is a pro-oxidant metabolite of glutathione and a precursor of cysteine. OBJECTIVE: To examine the relation between serum cysteine and cysteinylglycine and risk of gastric adenocarcinomas, esophageal squamous cell carcinomas, and head and neck squamous cell carcinomas, we conducted a nested case-control study within the Alpha-Tocopherol, Beta-Carotene Cancer Prevention study of male Finnish smokers aged 50-69 y at baseline...
September 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27524818/metabolomics-analysis-of-serum-25-hydroxy-vitamin-d-in-the-alpha-tocopherol-beta-carotene-cancer-prevention-atbc-study
#20
Shakira M Nelson, Orestis A Panagiotou, Gabriella M Anic, Alison M Mondul, Satu Männistö, Stephanie J Weinstein, Demetrius Albanes
BACKGROUND: Vitamin D has been discussed in the context of cardiovascular disease, cancer, bone health and other outcomes. Epidemiological studies have reported on the importance of vitamin D in cancer prevention and treatment. The discovery of vitamin D-associated metabolites through agnostic metabolomics analyses offers a new approach for elucidating disease aetiology and health-related pathway identification. METHODS: Baseline serum 25-hydroxy-vitamin D [25(OH)D] and 940 serum metabolites were measured in 392 men from eight nested cancer case-control studies in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study of Finnish male smokers (aged 50-69 years)...
August 14, 2016: International Journal of Epidemiology
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