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https://www.readbyqxmd.com/read/28205015/self-management-of-dietary-intake-using-mindful-eating-to-improve-dietary-intake-for-individuals-with-early-stage-chronic-kidney-disease
#1
Gayle M Timmerman, Muna J Tahir, Richard M Lewis, Deborah Samoson, Holli Temple, Michele R Forman
Using mindful eating to improve specific dietary recommendations has not been adequately studied. This feasibility study examined an intervention, self-management of dietary intake using mindful eating, with 19 participants that had mild to moderate chronic kidney disease, using a prospective, single group, pretest-posttest design. The intervention had six weekly classes focused on self-management using mindful eating, goal-setting, problem-solving, and food label reading. Weight, body mass index (BMI), 3-day 24-h dietary recalls and fasting blood samples were measured...
February 15, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28182846/encapsulation-of-beta-carotene-in-lipid-microparticles-stabilized-with-hydrolyzed-soy-protein-isolate-production-parameters-alpha-tocopherol-coencapsulation-and-stability-under-stress-conditions
#2
Thais C Brito-Oliveira, Camila V Molina, Flávia M Netto, Samantha C Pinho
The objectives of this research were to study the encapsulation of beta-carotene (BC) in solid lipid microparticles (SLM) of palm stearin (PS) and stabilized with hydrolyzed soy protein isolate (HSPI), and also to investigate the effect of alpha-tocopherol (TOC) addition to the systems. Through the characterizations of SLM produced with different formulations, it was verified that systems with 5% (w/v) PS, 1.0% (w/v) HSPI, and 0.3% (w/v) xanthan gum (XG) presented the highest stability, with average diameters of approximately 1...
February 9, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28163782/coupling-and-uncoupling-of-triglyceride-and-beta-carotene-production-by-dunaliella-salina-under-nitrogen-limitation-and-starvation
#3
Hubert Bonnefond, Nina Moelants, Amélie Talec, Patrick Mayzaud, Olivier Bernard, Antoine Sciandra
BACKGROUND: Nitrogen starvation and limitation are known to induce important physiological changes especially in lipid metabolism of microalgae (triglycerides, membrane lipids, beta-carotene, etc.). Although little information is available for Dunaliella salina, it is a promising microalga for biofuel production and biotechnological applications due to its ability to accumulate lipid together with beta-carotene. RESULTS: Batch and chemostat experiments with various degrees of nitrogen limitation, ranging from starvation to nitrogen-replete conditions, were carried out to study carbon storage dynamics (total carbon, lipids, and beta-carotene) in steady state cultures of D...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28154734/nutritional-and-lifestyle-interventions-for-age-related-macular-degeneration-a-review
#4
REVIEW
Ângela Carneiro, José Paulo Andrade
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. In this narrative review, we will summarize the nutritional interventions evaluated in numerous observational studies and a few randomized clinical trials. The AREDS and AREDS2 studies demonstrated that supplements including vitamins C and E, beta-carotene, and zinc may reduce the progression to advanced AMD, in some patients, by 25% in five years. This is one of the few nutritional supplements known to have beneficial effects in any eye disease...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28152319/evaluation-of-plasma-oxidative-stress-with-or-without-antioxidant-supplementation-in-superficial-partial-thickness-burn-patients-a-pilot-study
#5
Edoardo Raposio, Michele P Grieco, Edoardo Caleffi
BACKGROUND: Oxidative stress is one of the main causes of pathophysiological alterations observed during burn injury. The present pilot study aimed to determine whether a specific oral antioxidant supplementation could in any way influence free radical blood values in patients affected by superficial partial thickness burns. MATERIALS AND METHODS: Plasma oxidants and plasma antioxidant capacity were analysed in 20 superficial partial thickness burn patients for a 2-week period; patients were randomly divided into two groups, one of which was supported with a specifically designed oral antioxidant formula (Squalene 100 mg, Vitamin C 30 mg, Coenzyme Q10 10 mg, Zinc 5 mg, Beta Carotene 3...
February 2, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28125945/design-of-microemulsion-system-suitable-for-the-oral-delivery-of-poorly-aqueous-soluble-beta-carotene
#6
Peng Cheng, Darren Svirskis, Sung Je Lee, Indrawati Oey, Hae-Soo Kwak, Guanyu Chen, Craig Bunt, Jingyuan Wen
Beta-carotene is a potent antioxidant for maintaining human health. However, its oral absorption is low due to poor aqueous solubility of less than 1 µg/ml. A microemulsion delivery system was designed to solubilize beta-carotene towards enhancing its oral bioavailability. From seven pseudo-ternary diagrams constructed, three systems were selected with large microemulsion areas suitable for oral administration and dilution in the predominately aqueous gastrointestinal fluids. Conductivity and rheology characterization were conducted along four dilution lines within the selected systems...
January 27, 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28107993/using-multiple-process-analytical-technology-probes-to-monitor-multivitamin-blends-in-a-tableting-feed-frame
#7
Pedro Durão, Clémence Fauteux-Lefebvre, Jean-Maxime Guay, Nicolas Abatzoglou, Ryan Gosselin
As Process Analytical Technology (PAT) implementation grows in the pharmaceutical industry, more studies are being performed to evaluate its suitability in new applications and processes within the manufacturing chain. As the last step in tablet production, the compression stage represents a critical phase that ensures product quality. In-line control put in place at this stage has the potential to detect powder blends that are out of specification limits and, thus, help to improve product quality. The objectives of the present project are to quantify the composition of a commercial 31-component multivitamin powder blend in real time on an industrial feed frame, using 3 different PAT tools: light-induced fluorescence spectroscopy, near infrared spectroscopy and red, green and blue color imaging...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28096780/molecular-breeding-of-a-novel-orange-brown-tomato-fruit-with-enhanced-beta-carotene-and-chlorophyll-accumulation
#8
Ranjith Kumar Manoharan, Hee-Jeong Jung, Indeok Hwang, Namhee Jeong, Kang Hee Kho, Mi-Young Chung, Ill-Sup Nou
BACKGROUND: Tomatoes provide a significant dietary source of the carotenoids, lycopene and β-carotene. During ripening, carotenoid accumulation determines the fruit colors while chlorophyll degradation. These traits have been, and continue to be, a significant focus for plant breeding efforts. Previous work has found strong evidence for a relationship between CYC-B gene expression and the orange color of fleshy fruit. Other work has identified a point mutation in SGR that impedes chlorophyll degradation and causes brown flesh color to be retained in some tomato varieties...
2017: Hereditas
https://www.readbyqxmd.com/read/28096201/serum-c-peptide-total-and-high-molecular-weight-adiponectin-and-pancreatic-cancer-do-associations-differ-by-smoking
#9
Leticia M Nogueira, Christina C Newton, Michael N Pollak, Debra T Silverman, Demetrius Albanes, Satu Männistö, Stephanie J Weinstein, Eric J Jacobs, Rachael Z Stolzenberg-Solomon
BACKGROUND: Studies examining associations between circulating concentrations of C-peptide and total adiponectin, two biomarkers related to obesity and insulin secretion and sensitivity and pancreatic ductal adenocarcinoma (PDA) risk have shown inconsistent results and included limited numbers of smokers. METHODS: We examined associations of these biomarkers and high molecular weight (HMW) adiponectin with PDA, overall, and by smoking status. We conducted a pooled nested case-control analysis in 3 cohorts (Prostate, Lung, Colorectal, and Ovarian Cancer Trial, Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study, and Cancer Prevention Study-II), with 758 cases (435 current smokers) and 1052 controls (531 smokers) matched by cohort, age, sex, race, blood draw date and follow-up time...
January 17, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28077427/serum-trimethylamine-n-oxide-carnitine-choline-and-betaine-in-relation-to-colorectal-cancer-risk-in-the-alpha-tocopherol-and-beta-carotene-study
#10
Kristin A Guertin, Xinmin S Li, Barry I Graubard, Demetrius Albanes, Stephanie J Weinstein, James J Goedert, Zeneng Wang, Stanley L Hazen, Rashmi Sinha
BACKGROUND: TMAO, a choline-derived metabolite produced by gut microbiota, and its biomarker precursors have not been adequately evaluated in relation to colorectal cancer risk. METHODS: We investigated the relationship between serum concentrations of TMAO and its biomarker precursors (choline, carnitine and betaine) and incident colorectal cancer risk in a nested case-control study of male smokers in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study...
January 11, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28061399/transcriptome-sequencing-and-metabolic-pathways-of-astaxanthin-accumulated-in-haematococcus-pluvialis-mutant-under-15-co2
#11
Jun Cheng, Ke Li, Yanxia Zhu, Weijuan Yang, Junhu Zhou, Kefa Cen
Transcriptome sequencing and annotation was performed on Haematococcus pluvialis mutant red cells induced with high light under 15% CO2 to demonstrate why astaxanthin yield of the mutant was 1.7 times higher than that of a wild strain. It was found that 56% of 1947 differentially expressed genes were upregulated in mutant cells. Most significant differences were found in unigenes related to photosynthesis, carotenoid biosynthesis and fatty acid biosynthesis pathways. The pyruvate kinase increased by 3.5-fold in mutant cells...
March 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28054464/economic-improvement-of-continuous-pharmaceutical-production-via-the-optimal-control-of-a-multi-feed-bioreactor
#12
Jonathan P Raftery, Melanie R DeSessa, M Nazmul Karim
Projections on the profitability of the pharmaceutical industry predict a large amount of growth in the coming years. Stagnation over the last 20 years in product development has led to the search for new processing methods leading to improvements in profitability by the reduction of operating costs or the improvement of process productivity. This work proposes a novel multi-feed bioreactor system composed of independently controlled feeds for substrate(s) and media used as a supplement and allows for the free manipulation of the bioreactor supply rate and substrate concentrations to maximize bioreactor productivity and substrate utilization while reducing operating costs...
January 5, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/28034704/antioxidants-taken-orally-prior-to-diagnostic-radiation-exposure-can-prevent-dna-injury
#13
Nivethan Velauthapillai, Joe Barfett, Hussein Jaffer, David Mikulis, Kieran Murphy
PURPOSE: To evaluate efficacy of oral antioxidant treatment given to patients before radiologic procedures in reducing x-ray-induced DNA damage. MATERIALS AND METHODS: In a single-center prospective controlled trial, antioxidant treatment with 2 g ascorbate, 1.2 g N-acetylcysteine, 600 mg lipoic acid, and 30 mg beta carotene was given to 5 consecutive participants before undergoing clinically indicated technetium-99m methylene diphosphonate ((99m)Tc MDP) bone scans for cancer staging...
December 26, 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28031192/identifying-biomarkers-of-dietary-patterns-by-using-metabolomics
#14
Mary C Playdon, Steven C Moore, Andriy Derkach, Jill Reedy, Amy F Subar, Joshua N Sampson, Demetrius Albanes, Fangyi Gu, Jukka Kontto, Camille Lassale, Linda M Liao, Satu Männistö, Alison M Mondul, Stephanie J Weinstein, Melinda L Irwin, Susan T Mayne, Rachael Stolzenberg-Solomon
BACKGROUND: Healthy dietary patterns that conform to national dietary guidelines are related to lower chronic disease incidence and longer life span. However, the precise mechanisms involved are unclear. Identifying biomarkers of dietary patterns may provide tools to validate diet quality measurement and determine underlying metabolic pathways influenced by diet quality. OBJECTIVE: The objective of this study was to examine the correlation of 4 diet quality indexes [the Healthy Eating Index (HEI) 2010, the Alternate Mediterranean Diet Score (aMED), the WHO Healthy Diet Indicator (HDI), and the Baltic Sea Diet (BSD)] with serum metabolites...
February 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28017254/role-of-vitamin-a-metabolism-in-iih-results-from-the-idiopathic-intracranial-hypertension-treatment-trial
#15
J Libien, M J Kupersmith, W Blaner, M P McDermott, S Gao, Y Liu, J Corbett, M Wall
INTRODUCTION: Vitamin A and its metabolites (called retinoids) have been thought to play a role in the development of idiopathic intracranial hypertension (IIH). The IIH Treatment Trial (IIHTT) showed the efficacy of acetazolamide (ACZ) in improving visual field function, papilledema grade, quality of life and cerebrospinal fluid (CSF) pressure. We postulated that IIH patients would demonstrate elevated measures of vitamin A metabolites in the serum and CSF. METHODS: Comprehensive measures of serum vitamin A and its metabolites were obtained from 96 IIHTT subjects, randomly assigned to treatment with ACZ or placebo, and 25 controls with similar gender, age and body mass index (BMI)...
January 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28011986/carotenoid-intake-and-risk-of-non-hodgkin-lymphoma-a-systematic-review-and-dose-response-meta-analysis-of-observational-studies
#16
REVIEW
Feifei Chen, Jiyi Hu, Ping Liu, Jing Li, Zheng Wei, Peng Liu
Carotenoids may play a protective role in the development of non-Hodgkin lymphoma (NHL), but findings from epidemiological studies on the associations between carotenoid intake and NHL risk are inconsistent. We therefore performed a meta-analysis to systemically evaluate the associations. Eligible studies were identified by a search of PubMed, Web of Science, Embase, and article reference lists. We pooled risk estimates from individual studies using a random-effect model to quantify the associations between intakes of specific carotenoids and NHL risk...
December 24, 2016: Annals of Hematology
https://www.readbyqxmd.com/read/27941847/association-between-vitamin-a-retinol-and-carotenoid-intake-and-pancreatic-cancer-risk-evidence-from-epidemiologic-studies
#17
Xiaoyi Huang, Yisha Gao, Xiaosong Zhi, Na Ta, Hui Jiang, Jianming Zheng
Pancreatic cancer is a devastating disease with poor prognosis. The association between vitamin A, retinol and carotenoid intake and the risk of pancreatic cancer occurrence remains controversial, and therefore it is necessary to make a meta-analysis to clarify the association between vitamin A, retinol and carotenoid intake and pancreatic cancer risk. In the present study, PubMed and EMBASE databases were used to identify qualified studies. The association between dietary vitamin A, retinol and carotenoids was estimated by pooled odds ratios (ORs) and corresponding 95% confidence intervals (CIs)...
December 12, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27941116/greater-coronary-heart-disease-risk-with-lower-intensity-and-longer-duration-smoking-compared-with-higher-intensity-and-shorter-duration-smoking-congruent-results-across-diverse-cohorts
#18
Jay H Lubin, Demetrius Albanes, Jane A Hoppin, Honglei Chen, Catherine C Lerro, Stephanie J Weinstein, Dale P Sandler, Laura E Beane Freeman
INTRODUCTION: Relative risks (RRs) for coronary heart disease (CHD) by cigarettes/day exhibit a concave pattern, implying the RR increase with each additional cigarette/day consumed decreases with greater intensity. Interpreting this pattern faces limitations, since cigarettes/day alone does not fully characterize smoking-related exposure. A more complete understanding of smoking and CHD risk requires a more comprehensive representation of smoking. METHODS: Using Poisson regression, we applied a RR model in pack-years and cigarettes/day to analyze two diverse cohorts, the US Agricultural Health Study, with 4396 CHD events and 1 425 976 person-years of follow-up, and the Finnish Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study, with 5979 CHD events and 486 643 person-years...
December 9, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/27929676/antioxidant-supplementation-is-not-associated-with-long-term-quality-of-life-in-stage-ii-colorectal-cancer-survivors-a-follow-up-of-the-study-of-colorectal-cancer-survivors-cohort
#19
Cari Lewis Tsinovoi, Pengcheng Xun, Ka He
Cancer survivors are motivated to change lifestyle following diagnosis, but studies investigating the outcomes are scarce. The purpose of this study was to examine the associations between antioxidant supplementation and quality of life (QoL) in stage-II colorectal cancer survivors. Four-hundred-fifty-three survivors were enrolled from the North Carolina Cancer Registry from 2009 to 2011. Interview data on demography, treatment, health behaviors, and QoL were collected at diagnosis, and at 12 and 24 mo post-diagnosis...
January 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/27899367/intake-of-key-micronutrients-and-food-groups-in-patients-with-late-stage-age-related-macular-degeneration-compared-with-age-sex-matched-controls
#20
Bamini Gopinath, Gerald Liew, Joanna Russell, Victoria Cosatto, George Burlutsky, Paul Mitchell
BACKGROUND: Knowledge of the risk factor profile of patients presenting with late-stage age-related macular degeneration (AMD) could help identify the most frequent modifiable AMD precursors among people who are referred for treatment. We aimed to assess dietary behaviours by comparing adjusted mean intakes of micronutrients and major food groups (fruits, vegetables, fish) among patients with AMD and a sample of age-sex-matched controls. METHODS: Cross-sectional analysis of 480 late AMD cases and 518 population-based age-sex-matched controls with no AMD signs...
November 29, 2016: British Journal of Ophthalmology
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