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https://www.readbyqxmd.com/read/29333890/cigarette-smoking-and-quit-attempts-among-latinos-in-substance-use-disorder-treatment
#1
Anna Pagano, Noah Gubner, Thao Le, Joseph Guydish
BACKGROUND: Differences in tobacco use behaviors have been identified between Latinos and non-Latino whites in the general US population. Little is known about cigarette smoking and quitting behaviors of Latinos in treatment for substance use disorders (SUDs), who represent two major tobacco-vulnerable groups. OBJECTIVES: To compare, in a national sample of persons enrolled in SUD treatment, demographic, drug use, and smoking and quitting prevalence and behaviors between Latinos and non-Latino whites...
January 15, 2018: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/29315025/particulate-matter-emissions-of-different-brands-of-mentholated-cigarettes
#2
Julia Gerharz, Michael H K Bendels, Markus Braun, Doris Klingelhöfer, David A Groneberg, Ruth Mueller
Inhaling particulate matter (PM) in environmental tobacco smoke (ETS) endangers the health of non-smokers. Menthol, an additive in cigarettes, attenuates respiratory irritation of tobacco smoke. It reduces perceptibility of smoke and therefore passive smokers may inhale ETS unnoticed. To investigate a possible effect of menthol on PM concentrations (PM10, PM2.5 and PM1) ETS of four mentholated cigarette brands (Elixyr Menthol, Winston Menthol, Reyno Classic and Pall Mall Menthol Blast) with varying menthol content were analyzed...
January 9, 2018: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/29303963/attitudes-towards-potential-new-tobacco-control-regulations-among-u-s-adults
#3
Allison M Schmidt, Sarah D Kowitt, Allison E Myers, Adam O Goldstein
Favorable attitudes towards tobacco control policies can facilitate their implementation and success. We examined attitudes toward four potential U.S. Federal tobacco regulations (banning menthol from cigarettes, reducing nicotine levels in cigarettes, banning candy and fruit flavored electronic cigarettes, and banning candy and fruit flavored little cigars and cigarillos) and associations with individual and state variables. A nationally representative phone survey of 4337 adults assessed attitudes toward potential policies...
January 5, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29300749/preferring-more-e-cigarette-flavors-is-associated-with-e-cigarette-use-frequency-among-adolescents-but-not-adults
#4
Meghan E Morean, Ellyn R Butler, Krysten W Bold, Grace Kong, Deepa R Camenga, Dana A Cavallo, Patricia Simon, Stephanie S O'Malley, Suchitra Krishnan-Sarin
INTRODUCTION: Many e-cigarette users find the variety of e-cigarette flavors appealing. We examined whether preferences for e-liquid flavors and the total number of flavors preferred differed between samples of adolescent and adult e-cigarette users. We also examined whether these preferences were associated with e-cigarette use frequency for adolescents or adults, respectively. MATERIALS AND METHODS: The analytic samples comprised 1) 396 adolescent, past-month e-cigarette users from 5 Connecticut high schools who completed an anonymous, school-based survey in Fall 2014 (56...
2018: PloS One
https://www.readbyqxmd.com/read/29288650/cooling-relief-of-acute-and-chronic-itch-requires-trpm8-channels-and-neurons
#5
Radhika Palkar, Serra Ongun, Edward Catich, Natalie Li, Neil Borad, Angela Sarkisian, David D McKemy
Cooling or the application of mentholated liniments to the skin has been used to treat itch for centuries, yet remarkably little is known of how counter-stimuli such as these induce itch relief. Indeed, there is no clear consensus in the scientific literature as to whether or not cooling does in fact block the transduction of itch signals or if it is simply a placebo effect. This gap in our understanding led us to hypothesize that cooling is antipruritic and, like cooling analgesia, requires function of the cold-gated ion channel TRPM8, a receptor for menthol expressed on peripheral afferent nerve endings...
December 27, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29284458/menthol-cigarettes-and-the-public-health-standard-a-systematic-review
#6
Andrea C Villanti, Lauren K Collins, Raymond S Niaura, Stacey Y Gagosian, David B Abrams
BACKGROUND: Although menthol was not banned under the Tobacco Control Act, the law made it clear that this did not prevent the Food and Drug Administration from issuing a product standard to ban menthol to protect public health. The purpose of this review was to update the evidence synthesis regarding the role of menthol in initiation, dependence and cessation. METHODS: A systematic review of the peer-reviewed literature on menthol cigarettes via a PubMed search through May 9, 2017...
December 29, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29282887/air-assisted-dispersive-liquid-liquid-microextraction-based-on-a-new-hydrophobic-deep-eutectic-solvent-for-the-preconcentration-of-benzophenone-type-uv-filters-from-aqueous-samples
#7
Dandan Ge, Yi Zhang, Yixiu Dai, Shumin Yang
Deep eutectic solvents are considered as new and green solvents that can be widely used in analytical chemistry such as microextraction. In the present work, a new dl-menthol-based hydrophobic deep eutectic solvent was synthesized and used as extraction solvents in an air-assisted dispersive liquid-liquid microextraction method for preconcentration and extraction of benzophenone-type UV filters from aqueous samples followed by high-performance liquid chromatography with diode array detection. In an experiment, the deep eutectic solvent formed by dl-menthol and decanoic acid was added to an aqueous solution containing the UV filters, and then the mixture was sucked up and injected five times by using a glass syringe, and a cloudy state was achieved...
December 28, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/29282180/safety-and-antipruritic-efficacy-of-a-menthol-containing-moisturizing-cream
#8
Hong Liang Tey, Evelyn Yuxin Tay, Wei Ding Tan
Itch is frequently associated with dermatoses characterized by a defective skin barrier. We formulated an itch-relieving moisturizing cream containing 3% menthol and ceramides. Our aim was to evaluate the safety and antipruritic efficacy of application of this cream in volunteers with and without skin diseases. Volunteers were asked to apply the cream for 1 month on a minimum body surface area of 6%. Safety was assessed by the absence of contact dermatitis or other side effects, using a self-administered questionnaire completed at 5 minutes, 1 week, and 1 month after application...
2017: Skinmed
https://www.readbyqxmd.com/read/29258240/a-molecular-interpretation-on-the-different-penetration-enhancement-effect-of-borneol-and-menthol-towards-5-fluorouracil
#9
Ran Wang, Zhimin Wu, Shufang Yang, Shujuan Guo, Xingxing Dai, Yanjiang Qiao, Xinyuan Shi
Borneol and menthol are terpenes that are widely used as penetration enhancers in transdermal drug delivery. To explore their penetration-enhancement effects on hydrophilic drugs, 5-fluorouracil (5-FU) was selected as a model drug. An approach that combined in vitro permeation studies and coarse-grained molecular dynamics was used to investigate their penetration-enhancement effect on 5-FU. The results showed that although both borneol and menthol imparted penetration-enhancement effects on 5-FU, these differed in terms of their mechanism, which may account for the observed variations in penetration-enhancement effects...
December 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29247491/the-roles-of-trpv1-trpa1-and-trpm8-channels-in-chemical-and-thermal-sensitivity-of-the-mouse-oral-mucosa
#10
Tatjana I Kichko, Winfried Neuhuber, Gerd Kobal, Peter W Reeh
Spices in food and beverages and compounds in tobacco smoke interact with sensory irritant receptors of the transient receptor potential (TRP) cation channel family. TRPV1 (vanilloid type 1), TRPA1 (ankyrin 1) and TRPM8 (melastatin 8) not only elicit action potential signaling through trigeminal nerves, eventually evoking pungent or cooling sensations, but by their calcium conductance they also stimulate the release of calcitonin gene-related peptide (CGRP). This is measured as an index of neuronal activation to elucidate the chemo- and thermosensory transduction in the isolated mouse buccal mucosa of wildtypes and pertinent knockouts...
December 15, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29244740/chirality-dependent-interaction-of-d-and-l-menthol-with-biomembrane-models
#11
Pooja Gusain, Shinya Ohki, Kunihide Hoshino, Yoshio Tsujino, Naofumi Shimokawa, Masahiro Takagi
Chirality plays a vital role in biological membranes and has a significant effect depending on the type and arrangement of the isomer. Menthol has two typical chiral forms, d- and l-, which exhibit different behaviours. l-Menthol is known for its physiological effect on sensitivity (i.e. a cooling effect), whereas d-menthol causes skin irritation. Menthol molecules may affect not only the thermoreceptors on biomembranes, but also the membrane itself. Membrane heterogeneity (lipid rafts, phase separation) depends on lipid packing and acyl chain ordering...
December 15, 2017: Membranes
https://www.readbyqxmd.com/read/29238980/influence-of-paeoniflorin-and-menthol-on-puerarin-transport-across-mdck-and-mdck-mdr1-cells-as-blood-brain-barrier-in%C3%A2-vitro-model
#12
Bing Yang, Shouying Du, Yang Lu, Shan Jia, Mengdi Zhao, Jie Bai, Pengyue Li, Huichao Wu
OBJECTIVE: Our objective of this research was (1) to investigate the transport characteristics of puerarin through MDCK-MDR1 and MDCK cells and (2) to evaluate the effects of paeoniflorin and menthol on puerarin transport so as to (3) explore the enhancement mechanism. METHODS: The cytotoxicity of drugs on MDCK and MDCK-MDR1 was evaluated by the MTT assay, and the transport studies were performed in both directions. The membrane fluidity was evaluated by fluorescence recovery after photobleaching, and the membrane potential was estimated by the accumulation of DiBAC4(3) in the cells...
December 13, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/29235858/self-assembly-of-chiral-metal-organic-tetartoid
#13
Dong Luo, Xue-Zhi Wang, Chen Yang, Xiao-Ping Zhou, Dan Li
Chiral coordination cages feature both chirality and defined inner space, providing advanced molecular materials. A series of chiral 20-nucleous cobalt-imidazolate cages were synthesized by self-assembly of 72 sub-components, and feature novel structure of tetartoid (tetragonal pentagonal dodecahedron). Spontaneous resolution of racemic tetartoidal cages ( and ) into a conglomer-ate of homochiral crystals are observed, while both homochiral  and  tetartoidal cage can be obtained through the chiral induc-tion of (D)- and (L)-enantiomers of menthol, respectively...
December 13, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29219057/formulation-optimization-and-in-vitro-and-in-vivo-evaluation-of-lornoxicam-ethosomal-gels-with-penetration-enhancers
#14
Keke Li, Shanshan Gao, Baocheng Tian, Yanan Shi, Qingzhi Lv, Jingtian Han
BACKGROUND: Ethosomes, a novel type of percutaneous drug delivery carrier with a lipid bilayer structure, penetrate the skin barrier due to their deformability and malleability, and presence of ethanol that fluidizes lipids in the skin. In order to further enhance the delivery of drugs through the skin, penetration enhancers are widely used. OBJECTIVE: The objective of this work was to develop an optimized formulation of lornoxicam ethosomal gels, investigate skin permeability with the addition of penetration enhancers, and evaluate the in vivo pharmacodynamics of these formulations...
December 7, 2017: Current Drug Delivery
https://www.readbyqxmd.com/read/29217583/structure-of-the-cold-and-menthol-sensing-ion-channel-trpm8
#15
Ying Yin, Mengyu Wu, Lejla Zubcevic, William F Borschel, Gabriel C Lander, Seok-Yong Lee
Transient receptor potential melastatin (TRPM) cation channels are polymodal sensors that are involved in a variety of physiological processes. Within the TRPM family, member 8 (TRPM8) is the primary cold- and menthol-sensor in humans. We determined the cryo-electron microscopy structure of the full-length TRPM8 from the collared flycatcher at an overall resolution of ~4.1 Å. Our TRPM8 structure reveals a three-layered architecture. The amino-terminal domain with a fold distinct among known TRP structures, together with the carboxyl-terminal region, forms a large two-layered cytosolic ring that extensively interacts with the transmembrane channel layer...
December 7, 2017: Science
https://www.readbyqxmd.com/read/29209288/antimicrobial-effects-of-sulfonyl-derivative-of-2-5h-furanone-against-planktonic-and-biofilm-associated-methicillin-resistant-and-susceptible-staphylococcus-aureus
#16
Irshad S Sharafutdinov, Elena Y Trizna, Diana R Baidamshina, Maria N Ryzhikova, Regina R Sibgatullina, Alsu M Khabibrakhmanova, Liliya Z Latypova, Almira R Kurbangalieva, Elvira V Rozhina, Mareike Klinger-Strobel, Rawil F Fakhrullin, Mathias W Pletz, Mikhail I Bogachev, Airat R Kayumov, Oliwia Makarewicz
The gram-positive opportunistic bacterium Staphylococcus aureus is one of the most common causatives of a variety of diseases including skin and skin structure infection or nosocomial catheter-associated infections. The biofilm formation that is an important virulence factor of this microorganism renders the antibiotic therapy ineffective, because biofilm-embedded bacteria exhibit strongly increased tolerance to antimicrobials. Here, we describe a novel 3-chloro-5(S)-[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyloxy]-4-[4-methylphenylsulfonyl]-2(5H)-furanone (F105), possessing a sulfonyl group and l-menthol moiety...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29204463/effect-of-flavors-and-modified-risk-messages-on-e-cigarette-abuse-liability
#17
Andrew J Barnes, Rose S Bono, Rebecca C Lester, Thomas E Eissenberg, Caroline O Cobb
Objectives: To measure e-cigarettes' abuse liability compared to conventional tobacco cigarettes under flavor and message conditions amenable to regulation. Methods: Two studies used 2×2 within-subjects designs with factors of e-cigarette flavor (Study 1: tobacco vs. menthol; Study 2: cherry vs. unflavored) and message (Study 1: reduced harm vs. no message; Study 2: reduced exposure to carcinogens vs. no message) with cigarette smokers (N(total) = 36). Linear mixed effects models assessed abuse liability for tobacco products...
October 2017: Tobacco Regulatory Science
https://www.readbyqxmd.com/read/29201950/using-the-vape-shop-standardized-tobacco-assessment-for-retail-settings-v-stars-to-assess-product-availability-price-promotions-and-messaging-in-new-hampshire-vape-shop-retailers
#18
Amanda Y Kong, Jessica L Eaddy, Susan L Morrison, Donna Asbury, Kristine M Lindell, Kurt M Ribisl
Objectives: This is the first statewide census of the product availability, price promotions, and product messaging of vape shops. Methods: A comprehensive list of New Hampshire vape shops was developed through a previously validated online search method. Store audits were conducted in 55 stores between January and February 2016 using the Vape Shop Standardized Tobacco Assessment for Retail Settings (V-STARS). Results: Modifiable devices and cig-alikes were sold in 92...
April 2017: Tobacco Regulatory Science
https://www.readbyqxmd.com/read/29199751/a-closer-look-into-deep-eutectic-solvents-exploring-intermolecular-interactions-using-solvatochromic-probes
#19
C Florindo, A J S McIntosh, T Welton, L C Branco, I M Marrucho
Deep eutectic solvents (DESs) constitute a new class of ionic solvents that has been developing at a fast pace in recent years. Since these solvents are commonly suggested as green alternatives to organic solvents, it is important to understand their physical properties. In particular, polarity plays an important role in solvation phenomena. In this work, the polarity of different families of DESs was studied through solvatochromic responses of UV-vis absorption probes. Kamlet-Taft α, β, π* and ETN parameters were evaluated using different solvatochromic probes, as 2,6-dichloro-4-(2,4,6-triphenyl-N-pyridino)-phenolate (Reichardt's betaine dye 33), 4-nitroaniline, and N,N-diethyl-4-nitroaniline for several families of DESs based on cholinium chloride, dl-menthol and a quaternary ammonium salt ([N4444]Cl)...
December 4, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29197060/repellency-potential-of-essential-oils-against-housefly-musca-domestica-l
#20
Nitin Chauhan, Anushree Malik, Satyawati Sharma
In present study, the essential oils such as Mentha piperita (mentha oil, M.O), Cymbopogan citratus (lemongrass oil, LG.O), Citrus sinensis (orange oil, O.O), and Eucalyptus globulus (eucalyptus oil, E.O) were evaluated for repellency against housefly (Musca domestica) in a specially designed chamber. Further, to study any synergistic effect, essential oil combinations, i.e., M.O + LG.O, M.O + O.O, and M.O + E.O, were screened at 50:50 and 70:30 ratios. The results showed superior repellency of mentha and mentha + lemongrass (70:30) with RC95 value of 0...
December 2, 2017: Environmental Science and Pollution Research International
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