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https://www.readbyqxmd.com/read/28343359/characterization-of-pm2-5-chemical-composition-at-the-demokritos-suburban-station-in-athens-greece-the-influence-of-saharan-dust
#1
Vasiliki Vasilatou, Evangelia Diapouli, Dimitrios Abatzoglou, Evangelos B Bakeas, Michael Scoullos, Konstantinos Eleftheriadis
The aim of this work is to study the atmospheric concentrations of selected major and trace elements and ions found in PM2.5, at a suburban site in Athens, Greece, and discuss on the impact of the different sources. Special focus is given to the influence of Saharan dust episodes. The seasonal variability in the metal and ion concentrations is also examined. The results show that PM2.5 mass concentrations are significantly influenced by Saharan dust events; it is observed that when the PM2.5 concentration is higher than 25 μg/m(3), five out of six times, the air mass crossed North Africa at an altitude within the boundary layer...
March 25, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28342722/the-effects-of-graft-size-and-insertion-site-location-during-anterior-cruciate-ligament-reconstruction-on-intercondylar-notch-impingement
#2
Alexander D Orsi, Paul K Canavan, Askhan Vaziri, Ruben Goebel, Onaly A Kapasi, Hamid Nayeb-Hashemi
BACKGROUND: Intercondylar notch impingement is detrimental to the anterior cruciate ligament (ACL). Notchplasty is a preventative remodeling procedure performed on the intercondylar notch during ACL reconstruction (ACLR). This study investigates how ACL graft geometry and both tibial and femoral insertion site location may affect ACL-intercondylar notch interactions post ACLR. A range of ACL graft sizes are reported during ACLR, from six millimeters to 11mm in diameter. Variability of three millimeters in ACL insertion site location is reported during ACLR...
March 22, 2017: Knee
https://www.readbyqxmd.com/read/28342562/tackling-racism-as-a-wicked-public-health-problem-enabling-allies-in-anti-racism-praxis
#3
Heather Came, Derek Griffith
Racism is a "wicked" public health problem that fuels systemic health inequities between population groups in New Zealand, the United States and elsewhere. While literature has examined racism and its effects on health, the work describing how to intervene to address racism in public health is less developed. While the notion of raising awareness of racism through socio-political education is not new, given the way racism has morphed into new narratives in health institutional settings, it has become critical to support allies to make informing efforts to address racism as a fundamental cause of health inequities...
March 16, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28342408/finite-element-method-based-study-for-effect-of-adult-degenerative-scoliosis-on-the-spinal-vibration-characteristics
#4
Ming Xu, James Yang, Isador Lieberman, Ram Haddas
Finite element analysis was used to investigate the responses of five healthy subjects and five adult degenerative scoliosis (ADS) subjects to cyclic vibration. The dynamic responses of the healthy and scoliotic spines to the sinusoidal cyclic vibrations have been investigated in previous studies by simulation or experimental approaches. However, no simulation or experimental results were available for the ADS subjects. The effect of the ADS on the vibrational characteristics of spines remained unknown. The objective of this study was to compare differences of the dynamic responses to the cyclic vibration input between the healthy subjects and subjects with ADS...
March 22, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28337326/crystal-structures-of-erap2-complexed-with-inhibitors-reveal-pharmacophore-requirements-for-optimizing-inhibitor-potency
#5
Anastasia Mpakali, Petros Giastas, Rebecca Deprez-Poulain, Athanasios Papakyriakou, Despoina Koumantou, Ronan Gealageas, Sofia Tsoukalidou, Dionisios Vourloumis, Irene M Mavridis, Efstratios Stratikos, Emmanuel Saridakis
Endoplasmic reticulum aminopeptidase 2 assists with the generation of antigenic peptides for presentation onto Major Histocompatibility Class I molecules in humans. Recent evidence has suggested that the activity of ERAP2 may contribute to the generation of autoimmunity, thus making ERAP2 a possible pharmacological target for the regulation of adaptive immune responses. To better understand the structural elements of inhibitors that govern their binding affinity to the ERAP2 active site, we cocrystallized ERAP2 with a medium activity 3,4-diaminobenzoic acid inhibitor and a poorly active hydroxamic acid derivative...
March 9, 2017: ACS Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28336969/complete-genome-sequence-and-comparative-genomics-of-the-probiotic-yeast-saccharomyces-boulardii
#6
Indu Khatri, Rajul Tomar, K Ganesan, G S Prasad, Srikrishna Subramanian
The probiotic yeast, Saccharomyces boulardii (Sb) is known to be effective against many gastrointestinal disorders and antibiotic-associated diarrhea. To understand molecular basis of probiotic-properties ascribed to Sb we determined the complete genomes of two strains of Sb i.e. Biocodex and unique28 and the draft genomes for three other Sb strains that are marketed as probiotics in India. We compared these genomes with 145 strains of S. cerevisiae (Sc) to understand genome-level similarities and differences between these yeasts...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28335478/lactational-stage-of-pasteurized-human-donor-milk-contributes-to-nutrient-limitations-for-infants
#7
Christina J Valentine, Georgia Morrow, Amanda Reisinger, Kelly A Dingess, Ardythe L Morrow, Lynette K Rogers
BACKGROUND: Mother's own milk is the first choice for feeding preterm infants, but when not available, pasteurized human donor milk (PDM) is often used. Infants fed PDM have difficulties maintaining appropriate growth velocities. To assess the most basic elements of nutrition, we tested the hypotheses that fatty acid and amino acid composition of PDM is highly variable and standard pooling practices attenuate variability; however, total nutrients may be limiting without supplementation due to late lactational stage of the milk...
March 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28334706/repetitive-dna-a-versatile-tool-for-karyotyping-in-festuca-pratensis-huds
#8
Anna Křivánková, David Kopecký, Štěpán Stočes, Jaroslav Doležel, Eva Hřibová
FISH is a useful method to identify individual chromosomes in a karyotype and to discover their structural changes accompanying genome evolution and speciation. DNA probes for FISH should be chromosome specific and/or exhibit specific patterns of distribution along each chromosome. Such probes are not available in many plants including meadow fescue (Festuca pratensis Huds.), an important forage grass species. In the present study, various DNA repeats identified in Illumina shotgun sequences specific to chromosome 4F of F...
March 24, 2017: Cytogenetic and Genome Research
https://www.readbyqxmd.com/read/28334176/phylogenomic-systematics-of-ostariophysan-fishes-ultraconserved-elements-support-the-surprising-non-monophyly-of-characiformes
#9
Prosanta Chakrabarty, Brant C Faircloth, Fernando Alda, William B Ludt, Caleb D McMahan, Thomas J Near, Alex Dornburg, James S Albert, Jairo Arroyave, Melanie L J Stiassny, Laurie Sorenson, Michael E Alfaro
Ostariophysi is a superorder of bony fishes including more than 10,300 species in 1,100 genera and 70 families. This superorder is traditionally divided into five major groups (orders): Gonorynchiformes (milkfishes and sandfishes), Cypriniformes (carps and minnows), Characiformes (tetras and their allies), Siluriformes (catfishes), and Gymnotiformes (electric knifefishes). Unambiguous resolution of the relationships among these lineages remains elusive, with previous molecular and morphological analyses failing to produce a consensus phylogeny...
February 27, 2017: Systematic Biology
https://www.readbyqxmd.com/read/28333831/deployed-skills-training-for-whole-blood-collection-by-a-special-operations-expeditionary-surgical-team
#10
Linda C Benavides, Iain M Smith, Jerome M Benavides, Douglas M Bowley, Heidi A Doughty, Jonathan B Lundy
BACKGROUND: Non-compressible hemorrhage is the leading cause of potentially preventable battlefield death. Combining casualty retrieval from the battlefield and damage control resuscitation (DCR) within the "golden hour" increases survival. However, transfusion requirements may exceed the current blood component stocks held by forward surgical teams. Warm fresh whole blood (WFWB) is an alternative. We report WFWB transfusion training developed by and delivered to a US Golden Hour Offset Surgical Treatment Team (GHOST-T) and the resulting improvement in confidence with WFWB transfusion...
March 22, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28328504/blocked-elements-in-1-d-and-2-d-arrays-part-i-detection-and-basic-compensation-on-simulated-and-i-in-vivo-i-targets
#11
Marko Jakovljevic, Gianmarco Pinton, Jeremy J Dahl, Gregg Trahey
During a transcostal ultrasound scan, ribs and other highly attenuating and/or reflective tissue structures can block parts of the array. Blocked elements tend to limit the acoustic window and impede visualization of structures of interest. Here, we demonstrate a method to detect blocked elements and we measure the loss of image quality they introduce in simulation and in vivo. We utilize a fullwave simulation tool and a clinical ultrasound scanner to obtain element signals from fullysampled matrix arrays during simulated and in vivo transcostal liver scans, respectively...
March 16, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28328141/a-590-kb-deletion-caused-by-non-allelic-homologous-recombination-between-two-line-1-elements-in-a-patient-with-mesomelia-synostosis-syndrome
#12
Tomohiro Kohmoto, Takuya Naruto, Miki Watanabe, Yuji Fujita, Sae Ujiro, Nana Okamoto, Hideaki Horikawa, Kiyoshi Masuda, Issei Imoto
Mesomelia-synostoses syndrome (MSS) is a rare, autosomal-dominant, syndromal osteochondrodysplasia characterized by mesomelic limb shortening, acral synostoses, and multiple congenital malformations due to a non-recurrent deletion at 8q13 that always encompasses two coding-genes, SULF1 and SLCO5A1. To date, five unrelated patients have been reported worldwide, and MMS was previously proposed to not be a genomic disorder associated with deletions recurring from non-allelic homologous recombination (NAHR) in at least two analyzed cases...
April 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28327356/type-2-inositol-trisphosphate-receptor-gene-expression-in-hepatocytes-is-regulated-by-cyclic-amp
#13
Emma Kruglov, M Ananthanarayanan, Pedro Sousa, Jittima Weerachayaphorn, Mateus T Guerra, Michael H Nathanson
The type 2 inositol 1,4,5-trisphosphate receptor (IP3R2) is the principal intracellular Ca(2+) release channel in hepatocytes, and so is important for bile secretion and other functions. IP3R2 activity is regulated in part by post-translational modifications but little is known about transcriptional regulation of its expression. We found that both IP3R2 mRNA and protein levels in liver were increased during fasting. Treatment of hepatocytes with forskolin or 8-CPT-cAMP also increased IP3R2, and this was reduced by actinomycin D...
March 18, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28326571/family-centred-service-differences-in-what-parents-of-children-with-cerebral-palsy-rate-important
#14
M Terwiel, M W Alsem, R C Siebes, K Bieleman, M Verhoef, M Ketelaar
BACKGROUND: A family-centred approach to services of children with disabilities is widely accepted as the foundational approach to service delivery in paediatric health care. The 56 items of the Measure of Processes of Care questionnaire (MPOC-56) all reflect elements of family-centred service. In this study, we investigated which elements of family-centred service are rated important by parents of children with cerebral palsy by adding a question on importance to each item of the MPOC-56 (MPOC-56-I)...
March 22, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28326196/iact-cel-a-feasibility-trial-of-a-face-to-face-and-internet-based-acceptance-and-commitment-therapy-intervention-for-chronic-pain-in-singapore
#15
Su-Yin Yang, Rona Moss-Morris, Lance M McCracken
Psychological interventions are increasingly utilising online or mobile phone based platforms to deliver treatment, including that for people with chronic pain. The aims of this study were to develop an adapted form of Acceptance and Commitment Therapy (ACT) for chronic pain in Singapore and to test the feasibility of elements of this treatment delivered via the internet and email. Methods. Thirty-three participants recruited from a tertiary pain management clinic and via the clinic website participated in this program over a period of five weeks with a 3-month follow-up...
2017: Pain Research and Treatment
https://www.readbyqxmd.com/read/28326162/trauma-informed-care-for-children-in-the-ambulance-international-survey-among-pre-hospital-providers
#16
Eva Alisic, Mark P Tyler, Melita J Giummarra, Rahim Kassam-Adams, Juul Gouweloos, Markus A Landolt, Nancy Kassam-Adams
Background: Pre-hospital providers, such as paramedics and emergency medical technicians, are in a position to provide key emotional support to injured children and their families. Objective: Our goal was to examine (a) pre-hospital providers' knowledge of traumatic stress in children, attitudes towards psychosocial aspects of care, and confidence in providing psychosocial care, (b) variations in knowledge, attitudes, and confidence according to demographic and professional characteristics, and (c) training preferences of pre-hospital providers regarding psychosocial care to support paediatric patients and their families...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/28324178/complete-genome-sequence-analysis-of-a-novel-staphylococcus-phage-stap1-and-proposal-of-a-new-species-in-the-genus-silviavirus
#17
Amal Senevirathne, Kuntal Ghosh, Eunjung Roh, Kwang-Pyo Kim
Bacteriophage StAP1 was isolated from a soil sample infecting Staphylococcus aureus and S. xylosus. Its genome was found to be 135,502 base pairs (bp) long with 30.00 mol% G+C content and 192 open reading frames. While no tRNA encoding genes were identified, 7 mobile elements were found to interrupt five StAP1 open reading frames. Comparative genomic and proteomic analysis consistently supports the establishment of a new species in the genus Silviavirus.
March 21, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28322395/a-simple-synthetic-route-to-polyoxovanadate-based-organic-inorganic-hybrids-using-eedq-as-an-ester-coupling-agent
#18
Aruuhan Bayaguud, JianDa Li, Shan She, Yongge Wei
A reaction strategy for the post-functionalization of hexavanadate derivatives is presented herein. In this study, five polyoxovanadate-based organic-inorganic hybrids TBA2[V6O13{(OCH2)3CCOO(CH2)15CH3}2] (2), TBA2[V6O13{(OCH2)3CCOO(CH2)8CH[double bond, length as m-dash]CH2}2] (3), TBA2[V6O13{(OCH2)3CCOOCH2CF3}2] (4), TBA2[V6O13{(OCH2)3CCOO(CH2CH2O)3CH3}2] (5), and TBA2[V6O13{(OCH2)3CCOO(CH2)12OH}2]·2CH3CH2OH (6) were successfully synthesized via esterification of carboxylic acid groups-containing TBA2[V6O13{(OCH2)3CCOOH}2] (1) with five alcohols possessing different functional groups...
March 21, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28320202/identification-and-expression-of-equine-mer-derived-mirnas
#19
Jeong-An Gim, Heui-Soo Kim
MicroRNAs (miRNAs) are single-stranded, small RNAs (21-23 nucleotides) that function in gene silencing and translational inhibition via the RNA interference mechanism. Most miRNAs originate from host genomic regions, such as intergenic regions, introns, exons, and transposable elements (TEs). Here, we focused on the palindromic structure of medium reiteration frequencies (MERs), which are similar to precursor miRNAs. Five MER consensus sequences (MER5A1, MER53, MER81, MER91C, and MER117) were matched with paralogous transcripts predicted to be precursor miRNAs in the horse genome (equCab2) and located in either intergenic regions or introns...
March 21, 2017: Molecules and Cells
https://www.readbyqxmd.com/read/28319117/comparative-genomics-of-clavibacter-michiganensis-subspecies-pathogens-of-important-agricultural-crops
#20
James T Tambong
Subspecies of Clavibacter michiganensis are important phytobacterial pathogens causing devastating diseases in several agricultural crops. The genome organizations of these pathogens are poorly understood. Here, the complete genomes of 5 subspecies (C. michiganensis subsp. michiganensis, Cmi; C. michiganensis subsp. sepedonicus, Cms; C. michiganensis subsp. nebraskensis, Cmn; C. michiganensis subsp. insidiosus, Cmi and C. michiganensis subsp. capsici, Cmc) were analyzed. This study assessed the taxonomic position of the subspecies based on 16S rRNA and genome-based DNA homology and concludes that there is ample evidence to elevate some of the subspecies to species-level...
2017: PloS One
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