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https://www.readbyqxmd.com/read/29150195/anatomic-findings-associated-with-epispadias-in-boys-implications-for-surgical-management-and-urinary-continence
#1
M Cendron, P S Cho, M Pennison, I Rosoklija, D A Diamond, J G Borer
INTRODUCTION: Pre-operative physical examination of male epispadias allows for classification of epispadias level as glanular (GE), penile (PE) or penopubic (PPE), and for delineation of anatomic anomalies. The incidence of associated extragenital abnormalities, such as vesicoureteral reflux (VUR), bladder neck (BN) abnormality and abnormal pubic diastasis (PD), and their impact on urinary continence has not yet been systematically studied. OBJECTIVE: The goal of this study was to evaluate whether the more proximal level of epispadias correlated with associated extragenital anatomic anomalies seen on initial imaging or endoscopic evaluation, and whether these pre-operative findings contributed to subsequent surgical management and impacted on achieving urinary continence...
October 26, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29149432/ebola-in-the-netherlands-2014-2015-costs-of-preparedness-and-response
#2
Anita W M Suijkerbuijk, Corien M Swaan, Marie-Josee J Mangen, Johan J Polder, Aura Timen, Wilhelmina L M Ruijs
The recent epidemic of Ebola virus disease (EVD) resulted in countries worldwide to prepare for the possibility of having an EVD patient. In this study, we estimate the costs of Ebola preparedness and response borne by the Dutch health system. An activity-based costing method was used, in which the cost of staff time spent in preparedness and response activities was calculated based on a time-recording system and interviews with key professionals at the healthcare organizations involved. In addition, the organizations provided cost information on patient days of hospitalization, laboratory tests, personal protective equipment (PPE), as well as the additional cleaning and disinfection required...
November 17, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/29136076/enhancing-the-photostability-of-poly-phenylene-ethynylene-for-single-particle-studies
#3
C F Calver, B A Lago, K S Schanze, G Cosa
Single molecule fluorescence (SMF) studies on conjugated polymers yield enhanced information on exciton dynamics and on the interplay between polymer conformation/morphology and photophysical behavior. SMF studies, however, demand good signal stability, excellent photostability, and high photon yields (a measure of both photostability and brightness) and thus the development of strategies to help conjugated polymers (CPs) meet these requirements is a topic of great interest. Here, we evaluate the effect of a number of triplet quencher additives on the photostability of a 49-mer long poly(phenylene-ethynylene) conjugated polymer bearing carboxylate side groups (PPE-CO2-49) that is deposited onto 100 nm diameter SiO2 nanoparticles (NPs)...
November 14, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/29123158/inhibition-of-phosphatidylinositol-3-kinease-suppresses-formation-and-progression-of-experimental-abdominal-aortic-aneurysms
#4
Jing Yu, Rui Liu, Jianhua Huang, Lixin Wang, Wei Wang
Accumulating evidence suggests an important role of Phosphatidylinositol 3-kinease (PI3K) pathway in inflammatory cells infiltration. Given  the essential role of inflammatory cells infiltration during the formation and progression of abdominal aortic aneurysm (AAA), to investigate the possibility of preventing AAA formation and progression via targeting PI3K is anticipated. Here, experimental AAAs was created in rats by transient intraluminal porcine pancreatic elastase (PPE) infusion into the infrarenal aorta firstly...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29116636/pe-and-ppe-genes-a-tale-of-conservation-and-diversity
#5
Giovanni Delogu, Michael J Brennan, Riccardo Manganelli
PE and PPE are two large families of proteins typical of mycobacteria whose structural genes in the Mycobacterium tuberculosis complex (MTBC) occupy about 7% of the total genome. The most ancestral PE and PPE proteins are expressed by genes that belong to the same operon and in most cases are found inserted in the esx clusters, encoding a type VII secretion system. Duplication and expansion of pe and ppe genes, coupled with intragenomic and intergenomic recombination events, led to the emergence of the polymorphic pe_pgrs and ppe_mptr genes in the MTBC genome...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29114998/early-and-delayed-post-pneumonectomy-empyemas-microbiology-management-and-prognosis
#6
Jean-Baptiste Stern, Ludovic Fournel, Benjamin Wyplosz, Philippe Girard, Malik AlNakib, Dominique Gossot, Agathe Seguin-Givelet
INTRODUCTION: Post-pneumonectomy empyema (PPE) is the most severe complication of pneumonectomy. Microbiology and its impact on management and prognosis have rarely been reported Methods: We retrospectively reviewed the files of a series of 37 consecutive patients with PPE over a 10-year period with a special focus on microbiology, means used to treat empyema, and prognosis. RESULTS: PPE occurred within 14 days of pneumonectomy in 17 cases (early PPE) and after postoperative day 16 in 20 patients (delayed PPE)...
November 8, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29107371/understanding-farmers-safety-behaviour-towards-pesticide-exposure-and-other-occupational-risks-the-case-of-zanjan-iran
#7
Rohallah Rezaei, Christos A Damalas, Gholamhossein Abdollahzadeh
Preventive interventions for reducing occupational risks and health problems among farmers require the identification of factors contributing to unsafe behaviour, but research on this topic is rather limited. A theoretical model for studying factors affecting farmers' use of occupational safety and health (OSH) practices in Iran was developed. The model was empirically tested using data collected from a survey of 301 tomato farmers of Zanjan Province of Iran. The examined OSH practices encompassed a wide range of behaviours, grouped in four categories, i...
October 26, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29100513/ghrelin-therapy-improves-lung-and-cardiovascular-function-in-experimental-emphysema
#8
Nazareth de Novaes Rocha, Milena Vasconcellos de Oliveira, Cássia Lisboa Braga, Gabriela Guimarães, Lígia de Albuquerque Maia, Gisele de Araújo Padilha, Johnatas Dutra Silva, Christina Maeda Takiya, Vera Luiza Capelozzi, Pedro Leme Silva, Patricia Rieken Macedo Rocco
BACKGROUND: Emphysema is a progressive disease characterized by irreversible airspace enlargement followed by a decline in lung function. It also causes extrapulmonary effects, such as loss of body mass and cor pulmonale, which are associated with shorter survival and worse clinical outcomes. Ghrelin, a growth-hormone secretagogue, stimulates muscle anabolism, has anti-inflammatory effects, promotes vasodilation, and improves cardiac performance. Therefore, we hypothesized that ghrelin might reduce lung inflammation and remodelling as well as improve lung mechanics and cardiac function in experimental emphysema...
November 3, 2017: Respiratory Research
https://www.readbyqxmd.com/read/29099468/assessing-acute-symptoms-related-to-occupational-exposures-among-nail-salon-technicians
#9
Derek G Shendell, Judith M Graber, Lindsey J Milich, Michael E Pratt
OBJECTIVE: This cross-sectional field study evaluated potential associations between acute symptoms among nail technicians and exposure of chemical hazards in New Jersey salons. METHODS: In 2016, an in-person safety and health survey was conducted. Data were gathered on symptoms, demographics, work history, tobacco use, area and/or task ventilation, use of personal protective equipment (PPE), and safety training. Workplace hazards were identified by observational survey during site visit walk-throughs...
November 2, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29096853/plasma-filtration-for-the-controlled-removal-of-liposomal-therapeutics-from-the-apheretic-site-of-view
#10
M Blaha, J Martinkova, M Lanska, S Filip, J Malakova, O Kubecek, J Bezouska, J Spacek
INTRODUCTION: Nanoparticle-based drug delivery systems can overcome the dose-limited toxicity of cytostatics. Pegylated doxorubicin-containing liposomes (PLD) are able to reduce cardiotoxicity. PLD quickly (in 2 days) attains therapeutic concentration in tumorous tissue (kinetic targeting), while its distribution in normal tissue, which is a cause of mucocutaneous toxicity (MCT), is delayed. We examined PLD extracorporeal removal effectivity, using plasma filtration (PF) to determine whether the drug could be withheld prior to its organ distribution responsible for MCT toxicity...
November 2017: Atherosclerosis. Supplements
https://www.readbyqxmd.com/read/29083344/invasive-meningococcal-disease-on-the-workplaces-a-systematic-review
#11
Matteo Riccò, Luigi Vezzosi, Anna Odone, Carlo Signorelli
Background and aims of the work: Invasive Meningococcal Disease (IMD) represents a global health threat, and occupational settings have the potential to contribute to its spreading. Therefore, here we present the available evidences on the epidemiology of IMD on the workplaces. METHODS: The following key words were used to explore PubMed: Neisseria meningitidis, meningococcus, meningococcal, invasive meningococcal disease, epidemiology, outbreaks, profession(al), occupation(al). RESULTS: We identified a total of 12 IMD cases among healthcare workers (HCW), 44 involving biological laboratory workers (BLW), 8 among school personnel, and eventually 27 from other settings, including 3 large industrial working populations...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29081844/fingerprinting-antibiotics-with-pae-based-fluorescent-sensor-arrays
#12
Jinsong Han, Benhua Wang, Markus Bender, Jessica Pfisterer, Wei Huang, Kai Seehafer, Mahdieh Yazdani, Vincent M Rotello, Caren M Rotello, Uwe H F Bunz
We outline an evolution process for tongue elements composed of poly(p-aryleneethynylene)s (PAE) and detergents, resulting in a chemical tongue (24 elements) that discerns antibiotics. Cross-breeding of this new tongue with tongue elements that consist of simple poly(p-phenyleneethynylene)s (PPE) at different pH-values leads to an enlarged sensor array, composed of 30 elements. This tongue was pruned, employing principal component analysis. We find that a filial tongue featuring three elements from each original array (i...
2017: Polymer Chemistry
https://www.readbyqxmd.com/read/29074070/comparison-of-intubation-devices-in-level-c-personal-protective-equipment-a-cadaveric-study
#13
R Scott Taylor, Matthew Pitzer, Grayson Goldman, Augusta Czysz, Thomas Simunich, John Ashurst
BACKGROUND: With the advancement of chemical, biological and nuclear warfare and the reemergence of infectious diseases, the possibility of intubating in personal protective equipment has become increasingly more real to the emergency physician. Human cadaveric models have been found to simulate real world conditions better than mannequins. The aim of the study was to determine the first pass success rate and average time to successful intubation while wearing Personal Protective Equipment (PPE)...
October 18, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29064868/association-between-previous-injury-and-risk-factors-for-future-injury-in-preprofessional-ballet-and-contemporary-dancers
#14
Sarah J Kenny, Luz Palacios-Derflingher, Qian Shi, Jackie L Whittaker, Carolyn A Emery
OBJECTIVES: To determine the prevalence of self-reported 1-year injury history and examine its association with preparticipation evaluation components aimed at predicting future injury risk (PPE-IP) among preprofessional ballet and contemporary dancers. DESIGN: Cross-sectional study. SETTING: Preprofessional ballet school, university contemporary dance program. PARTICIPANTS: Full-time preprofessional ballet and contemporary dancers...
October 20, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29058966/high-level-isolation-unit-infection-control-procedures
#15
Jocelyn J Herstein, Paul D Biddinger, Shawn G Gibbs, Aurora B Le, Katelyn C Jelden, Angela L Hewlett, John J Lowe
The 2014-2016 Ebola outbreak in West Africa prompted a select group of US hospitals to establish high-level isolation units equipped with advanced engineering controls, trained staff, and stringent protocols to safely treat highly infectious disease patients. This survey details the comprehensive infection control protocols developed by these units, including for decontamination of units, post-mortem management, liquid waste disposal, and personal protective equipment (PPE) use. In spring 2016, a survey was electronically distributed to the 56 original Centers for Disease Control and Prevention (CDC)-designated high-level isolation units...
September 2017: Health Security
https://www.readbyqxmd.com/read/29058570/occupational-noise-exposure-and-hearing-defects-among-sawmill-workers-in-the-south-of-thailand
#16
Phayong Thepaksorn, Akio Koizumi, Kouji Harada, Wattasit Siriwong, Richard L Neitzel
The aim of this study was to investigate occupational noise exposure and hearing defects among sawmill workers in the South of Thailand. Seven hundred sawmill workers participated, of which 335 (47.9%) were male. The mean age of the sawmill workers was 33.5 years old (SD = 10.2), and more than 60% were <35 years old. 75.1% of the workers had less than 5 years of work experience. Only about one in four workers (25%) had been trained on use of personal protective equipment (PPE), and half of participants never or rarely wore PPEs while working...
October 23, 2017: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/29050907/difficulties-in-using-personal-protective-equipment-training-experiences-with-the-2015-outbreak-of-middle-east-respiratory-syndrome-in-korea
#17
JaHyun Kang, Eun Jin Kim, Jeong Hwa Choi, Hae Kyung Hong, Si-Hyeon Han, In Soon Choi, Jae Geum Ryu, Jinwha Kim, Jae Yeun Kim, Eun Suk Park
This study aimed to evaluate practical barriers to personal protective equipment (PPE) use found through health care personnel (HCP) training sessions held during and after the 2015 Middle East respiratory syndrome outbreak in Korea. Difficulties observed were ill-fitting sizes, anxiety, confusion from unstandardized protocols, doubts about PPE quality and effectiveness, and complexity of using several PPE items together. Further research to generate robust evidence and repeated HCP trainings are necessary to ensure HCP and patient safety in future outbreaks...
October 16, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/29045708/association-between-polycyclic-aromatic-hydrocarbon-exposure-and-peripheral-blood-mononuclear-cell-dna-damage-in-human-volunteers-during-fire-extinction-exercises
#18
Maria Helena Guerra Andersen, Anne Thoustrup Saber, Per Axel Clausen, Julie Elbæk Pedersen, Mille Løhr, Ali Kermanizadeh, Steffen Loft, Niels Ebbehøj, Åse Marie Hansen, Peter Bøgh Pedersen, Ismo Kalevi Koponen, Eva-Carina Nørskov, Peter Møller, Ulla Vogel
This study investigated a number of biomarkers, associated with systemic inflammation as well as genotoxicity, in 53 young and healthy subjects participating in a course to become firefighters, while wearing personal protective equipment (PPE). The exposure period consisted of a 3-day training course where the subjects participated in various live-fire training exercises. The subjects were instructed to extinguish fires of either wood or wood with electrical cords and mattresses. The personal exposure was measured as dermal polycyclic aromatic hydrocarbon (PAH) concentrations and urinary excretion of 1-hydroxypyrene (1-OHP)...
October 13, 2017: Mutagenesis
https://www.readbyqxmd.com/read/29021506/computational-wave-dynamics-for-innovative-design-of-coastal-structures
#19
Hitoshi Gotoh, Akio Okayasu
For innovative designs of coastal structures, Numerical Wave Flumes (NWFs), which are solvers of Navier-Stokes equation for free-surface flows, are key tools. In this article, various methods and techniques for NWFs are overviewed. In the former half, key techniques of NWFs, namely the interface capturing (MAC, VOF, C-CUP) and significance of NWFs in comparison with the conventional wave models are described. In the latter part of this article, recent improvements of the particle method are shown as one of cores of NWFs...
2017: Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
https://www.readbyqxmd.com/read/29021414/development-of-bioassay-system-for-evaluation-of-materials-for-personal-protective-equipment-ppe-against-toxic-effects-of-ionizing-radiations
#20
Masatake Yamauchi, Sachiko Sakuma
Health effects caused by ionizing radiations raise considerable concern among general public and radiation workers. To estimate ability of personal protective equipment (PPE) materials that reduce toxic effects of ionizing radiations, we developed an experimental bioassay system using Chinese Hamster V79 cells. The system developed here distinguished the biological effectiveness of X-ray that was significantly affected by elements composed of shielding materials. Survival of the cells exposed to sub-lethal dose of X-ray was enhanced more than 2 times when the X-ray was filtrated by a lead plate...
October 11, 2017: Industrial Health
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