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https://www.readbyqxmd.com/read/28515649/effect-of-persimmon-peel-diospyros-kaki-thumb-extracts-on-lipid-and-protein-oxidation-of-raw-ground-pork-during-refrigerated-storage
#1
Ju-Hui Choe, Hack-Youn Kim, Cheon-Jei Kim
The inhibition effect of persimmon peel extracts (PPE) (0.05(PPE-0.05), 0.1(PPE-0.1), and 0.2 g(PPE-0.2) per meat sample) on lipid and protein oxidation of pork patties during chilled storage for 12 days were investigated and compared to ascorbic acid (As-0.05) and butylhydroxytoluene (BHT) (BHT-0.01). The meat samples treated with PPE had greater (p<0.05) a* values comparing control in raw pork patties meat from day 4 of storage. The addition of PPE at all concentrations on meat samples effectively inhibited the formation of oxidation products as shown by decreasing conjugated dienes (CD), peroxide values (POVs), thiobarbituric acid reaction substances (TBARS), and carbonyl content during chilled storage for 12 d...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/28511344/anti-inflammatory-effects-of-trans-anethole-in-a-mouse-model-of-chronic-obstructive-pulmonary-disease
#2
Ka Young Kim, Hui Su Lee, Geun Hee Seol
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that is generally characterized by progressive and irreversible airflow obstruction and alveolar destruction. Long-term treatment with current medications has been associated with various adverse effects, indicating a need for alternative approaches for the prevention and treatment of COPD. This study investigated the mechanism underlying the effects of trans-anethole in a mouse model of COPD induced by porcine pancreatic elastase (PPE) and lipopolysaccharide (LPS)...
May 12, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28510803/occupational-and-life-style-factors-acquired-mutagenicity-in-agric-workers-of-northeastern-brazil
#3
Tatiana Vieira Souza Chaves, Muhammad Torequl Islam, Manoel Odoríco de Moraes, Marcus Vinícius Oliveira Barros de Alencar, Débora Cássia Vieira Gomes, Rodrigo Mendes de Carvalho, Sharbel Weider Maluf, Fabrício Pires de Moura do Amaral, Márcia Fernanda Correia Jardim Paz, Gilberto Santos Cerqueira, Hercília Maria Lins Rolim, João Marcelo de Castro E Sousa, Ana Amélia de Carvalho Melo-Cavalcante, Maria Elisabete Amaral de Moraes
Pesticides are a complex mixture of chemicals used to protect crops from a number of pests and diseases. They have been considered as potential mutagenic agents. This study aims at evaluation of the mutagenic effect of pesticide exposure to agricultural workers through chromosomal aberrations (CA) and micronucleus (MN) assay in peripheral blood lymphocytes and oral mucosal cells, respectively. The exposed group was consisted with 97 farmers, while the control (un-exposed) group consisted of 55. The results showed a significant (p < 0...
May 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28508408/variations-in-status-of-preparation-of-personal-protective-equipment-for-preventing-norovirus-gastroenteritis-in-long-term-care-facilities-for-the-elderly
#4
Saori Fujiki, Tatsuro Ishizaki, Takeo Nakayama
RATIONALE, AIM, AND OBJECTIVES: Residents of long-term care facilities are highly susceptible to norovirus gastroenteritis, and each facility is concerned about the need to implement norovirus infection control. Among control measures, personal protective equipment (PPE), such as disposable gloves and masks, plays a major role in reducing infectious spread. However, the preparation status of PPE in facilities before infection outbreaks has not been reported. The aim was to clarify the implementation status of preventive measures for norovirus gastroenteritis and the cost of preparing the necessary PPE in long-term care facilities...
May 16, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28497336/the-overlapping-spectrum-of-flat-irregular-pigment-epithelial-detachment-investigated-by-optical-coherence-tomography-angiography
#5
Francesco Pichi, Mariachiara Morara, Chiara Veronese, Antonio P Ciardella
PURPOSE: To describe the OCT angiography characteristics of flat irregular pigment epithelial detachments (PEDs), an overlapping tomographic feature of various macular disorders. METHODS: Consecutive patients with a dimpled retinal pigment epithelium profile on OCT, referred for a second opinion, were enrolled. Fluorescein (FA) and indocyanine green angiography (ICGA) were performed in all patients and compared to previous examinations, when available. In all patients, enhanced depth imaging-OCT and OCT angiography were performed upon referral and at subsequent follow-ups...
May 11, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28493945/ebola-virus-rna-detection-on-fomites-in-close-proximity-to-confirmed-ebola-patients-n-zerekore-guinea-2015
#6
Romain Palich, Leonid M Irenge, Eric Barte de Sainte Fare, Augustin Augier, Denis Malvy, Jean-Luc Gala
OBJECTIVE: Health care workers (HCWs) in contact with patients with Ebola virus disease (EVD) are exposed to a risk of viral contamination. Fomites contaminated with the patient's blood or body fluids represents this risk. Our study aims to detect Ebola virus (EBOV) RNA within the high- and low-risk areas of an Ebola treatment unit (ETU) located in inland Guinea during the 2014-2015 West African Ebola epidemics. For samples from patients' immediate vicinity, we aim to seek an association between viral RNA detectability and level of plasma viral load of patients (intermediate to high, or very high)...
2017: PloS One
https://www.readbyqxmd.com/read/28492131/personal-protective-equipment-in-animal-research
#7
Jason S Villano, Janet M Follo, Mark G Chappell, Morris T Collins
The occupational health and safety program is an integral component of a comprehensive animal care and use program. Itisimportant to mitigate the risk of exposures of animal care and research personnel to allergens and physical, chemical, radiologic,and biologic hazards during the conduct of various tasks. This need is especially true in infectious disease and biocontainment research. One aspect of the program is the provision of personal protective equipment (PPE). Commercially available PPE should be carefully evaluated based on their material composition and performance according to manufacturer data...
May 10, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28487178/comparison-between-generalized-linear-modelling-and-additive-bayesian-network-identification-of-factors-associated-with-the-incidence-of-antibodies-against-leptospira-interrogans-sv-pomona-in-meat-workers-in-new-zealand
#8
M Pittavino, A Dreyfus, C Heuer, J Benschop, P Wilson, J Collins-Emerson, P R Torgerson, R Furrer
BACKGROUND: Additive Bayesian Network (ABN) is a graphical model which extends Generalized Linear Modelling (GLM) to multiple dependent variables. The present study compares results from GLM with those from ABN analysis used to identify factors associated with Leptospira interrogans sv Pomona (Pomona) infection by exploring the advantages and disadvantages of these two methodologies, to corroborate inferences informing health and safety measures at abattoirs in New Zealand (NZ). METHODOLOGY AND FINDINGS: in a cohort study in four sheep slaughtering abattoirs in NZ, sera were collected twice a year from 384 meat workers and tested by Microscopic Agglutination with a 91% sensitivity and 94% specificity for Pomona...
May 6, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28482453/health-hazards-and-adoption-of-personal-protective-equipment-during-cotton-harvesting-in-pakistan
#9
Khuda Bakhsh, Nameem Ahmad, Shanza Tabasum, Sarfraz Hassan, Ishtiaq Hassan
The use of personal protective equipment (PPE) during cotton harvesting is critical for securing better health for female cotton pickers in the developing countries where health facilities are not sufficiently available to the masses in the rural areas. Despite increasing the efforts in increasing awareness about the benefits of PPE among the farm workers, a vast majority of the farm workers including pickers don't use the PPE. The present study examines health impacts of cotton harvesting in Pakistani Punjab along with the factors affecting the use of PPE among the cotton pickers...
May 2, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28478772/are-dutch-hospitals-prepared-for-chemical-biological-or-radionuclear-incidents-a-survey-study
#10
Luc J M Mortelmans, Menno I Gaakeer, Greet Dieltiens, Kurt Anseeuw, Marc B Sabbe
Introduction Being one of Europe's most densely populated countries, and having multiple nuclear installations, a heavy petrochemical industry, and terrorist targets, the Netherlands is at-risk for chemical, biological, or radionuclear (CBRN) incidents. Recent world and continental events show that this threat is real and that authorities may be underprepared. Hypothesis The hypothesis of this study is that Dutch hospitals are underprepared to deal with these incidents. METHODS: A descriptive, cross-sectional study was performed...
May 8, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28476683/neurostimulation-therapy-for-pediatric-primary-enuresis-a-meta-analysis
#11
Michael E Chua, Nicolas Fernandez, Jessica M Ming, Jan Michael A Silangcruz, Joana Dos Santos, Armando J Lorenzo, Martin A Koyle, Roberto Iglesias Lopes
OBJECTIVES: To assess the efficacy and safety of neurostimulation compared to control groups in the treatment of pediatric primary enuresis (PPE) by performing meta-analysis of randomized controlled trials (RCTs) METHODS: A systematic literature search with no language restriction was done in August 2016. RCTs were identified and evaluated according to the Cochrane Collaboration risk of bias assessment recommendations. The number of patients with post-treatment: partial response /PR (50%-89%), complete response /CR (≥90%) and full response/ FR (100%) responses were extracted for relative risk (RR) and 95% confidence interval (CI)...
May 2, 2017: Urology
https://www.readbyqxmd.com/read/28471058/quantitative-analysis-of-hepatic-toxicity-in-rats-induced-by-inhalable-silica-nanoparticles-using-acoustic-radiation-force-imaging
#12
Wen Cao, Yajing Zhou, Yingmei Niu, Xiaoli Zhu, Yuguo Song, Ruijun Guo
OBJECTIVES: The purposes of this study were to verify whether inhalable silicon dioxide (SiO2 ) nanoparticles could induce hepatic injury and to investigate the relationship between the exposure time and SiO2 nanoparticle dosage by using acoustic radiation force impulse imaging (ARFI). METHODS: A total of 72 rats were randomly separated into 9 groups with 8 in each: blank control group, 0.9% normal saline group, polyacrylate (PPE) group, 25%, 50%, and 100% SiO2 groups, and 25%, 50%, and 100% SiO2 /PPE groups with inhaled SiO2 nanoparticle concentrations similar to the SiO2 groups...
May 4, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28460633/up-regulated-expression-of-substance-p-in-cd8-t-cells-and-nk1r-on-monocytes-of-atopic-dermatitis
#13
Zenan Zhang, Wenjiao Zheng, Hua Xie, Ruonan Chai, Junling Wang, Huiyun Zhang, Shaoheng He
BACKGROUND: Large numbers of CD8(+) T cells were observed in atopic dermatitis (AD) skin, and monocytes from AD patients showed increased prostaglandin E2 production. However, little is known about the expression of substance P (SP) and its receptor NK1R in blood leukocytes of patients with AD. OBJECTIVE: To explore the expression of SP and NK1R in leukocytes of AD and the influence of allergens on SP and NK1R expression. METHODS: The expression levels of SP and NK1R in patients with AD were examined by flow cytometry, ELISA and a mouse AD model...
May 1, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28440335/mycobacterium-tuberculosis-pe_pgrs41-enhances-the-intracellular-survival-of-m-smegmatis-within-macrophages-via-blocking-innate-immunity-and-inhibition-of-host-defense
#14
Wanyan Deng, Quanxin Long, Jie Zeng, Ping Li, Wenmin Yang, Xinchun Chen, Jianping Xie
The success of Mycobacterium tuberculosis (M. tuberculosis) as a pathogen is largely contributes to its ability to manipulate the host immune responses. The genome of M. tuberculosis encodes multiple immune-modulatory proteins, including several members of the multi-genic PE_PPE family. Despite of intense research, the roles of PE_PGRS proteins in mycobacterial pathogenesis remain elusive. The function of M. tuberculosis PE_PGRS41, characterized by an extended and unique C-terminal domain, was studied. Expression of PE_PGRS41 in Mycobacterium smegmatis, a non-pathogenic species intrinsically deficient of PE_PGRS, severely impaired the resistance of the recombinant to multiple stresses via altering the cell wall integrity...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28434702/inhibition-or-deletion-of-angiotensin-ii-type-1-receptor-suppresses-elastase-induced-experimental-abdominal-aortic-aneurysms
#15
Haojun Xuan, Baohui Xu, Wei Wang, Hiroki Tanaka, Naoki Fujimura, Masaaki Miyata, Sara A Michie, Ronald L Dalman
OBJECTIVE: Angiotensin (Ang) II type 1 receptor (AT1) activation is essential for the development of exogenous Ang II-induced abdominal aortic aneurysms (AAAs) in hyperlipidemic animals. Experimental data derived from this modeling system, however, provide limited insight into the role of endogenous Ang II in aneurysm pathogenesis. Consequently, the potential translational value of AT1 inhibition in clinical AAA disease management remains incompletely understood on the basis of the existing literature...
April 20, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28427270/skin-irritation-testing-of-antimicrobial-conjugated-electrolytes
#16
Kristin N Wilde, Phuong A H Nguyen, David G Whitten, Heather E Canavan
Each year, the United States spends about $20 billion to treat people who have been infected with antibiotic resistant bacteria. Even so, the development of new antibiotics has slowed considerably since the mid-20th century. As a result, researchers are looking into developing synthetic compounds and materials with antimicrobial activities such as those made by the Schanze and Whitten groups [ACS Appl. Mater. Interfaces 3, 2820 (2011)]. Previously, they have demonstrated that poly(phenylene ethynylene) (PPE) based electrolytes and oligomeric end-only phenylene ethynylene (EO-OPE) based electrolytes possess strong biocidal activity...
April 20, 2017: Biointerphases
https://www.readbyqxmd.com/read/28426630/outer-nuclear-layer-thinning-in-pachychoroid-pigment-epitheliopathy
#17
M Giray Ersoz, Murat Karacorlu, Serra Arf, Mumin Hocaoglu, Isil Sayman Muslubas
PURPOSE: To compare the average thicknesses of central inner retinal layers in eyes with pachychoroid pigment epitheliopathy (PPE), with uncomplicated pachychoroid (UCP), and of healthy subjects. METHODS: Medical records of patients with PPE and UCP were retrospectively reviewed. Twenty-nine eyes with foveal PPE, 30 eyes with UCP, and 29 eyes of healthy subjects were included. Spectral-domain optical coherence tomography with enhanced depth imaging was used for all optical coherence tomography scans...
April 19, 2017: Retina
https://www.readbyqxmd.com/read/28422931/development-and-psychometric-evaluation-of-the-professional-practice-work-environment-inventory
#18
Jeanette Ives Erickson, Mary E Duffy, Marianne Ditomassi, Dorothy Jones
OBJECTIVE: The purpose is to examine the psychometric properties of the professional practice work environment inventory (PPWEI). BACKGROUND: Derived from the Professional Practice Environment (PPE) and the Revised PPE scales, the PPWEI was designed to measure 8 components of the PPE that can be used to assist nurse administrators in decision-making. METHODS: A psychometric evaluation was undertaken with 874 nurses who were providing direct care to patients at the Massachusetts General Hospital and who provided no missing data on the newly developed 72-item PPWEI...
May 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28420487/personal-protective-equipment-solution-for-uk-military-medical-personnel-working-in-an-ebola-virus-disease-treatment-unit-in-sierra-leone
#19
P Reidy, T Fletcher, C Shieber, J Shallcross, H Towler, M Ping, L Kenworthy, N Silman, E Aarons
The combination of personal protective equipment (PPE) together with donning and doffing protocols was designed to protect British and Canadian military medical personnel in the Kerry Town Ebola Treatment Unit (ETU) in Sierra Leone. The PPE solution was selected to protect medical staff from infectious risks, notably Ebola virus, and chemical (hypochlorite) exposure. PPE maximized dexterity, enabled personnel to work in hot temperatures for periods of up to 2h, protected mucosal membranes when doffing outer layers, and minimized potential contamination of the doffing area with infectious material by reducing the requirement to spray PPE with hypochlorite...
March 18, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28418743/stockpile-model-of-personal-protective-equipment-in-taiwan
#20
Yu-Ju Chen, Po-Jung Chiang, Yu-Hsin Cheng, Chun-Wei Huang, Hui-Yun Kao, Chih-Kai Chang, Hsun-Miao Huang, Pei-Yin Liu, Jen-Hsin Wang, Yi-Chien Chih, Shu-Mei Chou, Chin-Hui Yang, Chang-Hsun Chen
The Taiwan Centers for Disease Control (Taiwan CDC) has established a 3-tier personal protective equipment (PPE) stockpiling framework that could maintain a minimum stockpile for the surge demand of PPE in the early stage of a pandemic. However, PPE stockpiling efforts must contend with increasing storage fees and expiration problems. In 2011, the Taiwan CDC initiated a stockpile replacement model in order to optimize the PPE stockpiling efficiency, ensure a minimum stockpile, use the government's limited funds more effectively, and achieve the goal of sustainable management...
March 2017: Health Security
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