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https://www.readbyqxmd.com/read/28318455/airway-management-in-disaster-response-a-manikin-study-comparing-direct-and-video-laryngoscopy-for-endotracheal-intubation-by-prehospital-providers-in-level-c-personal-protective-equipment
#1
Sami Yousif, Jason T Machan, Yasser Alaska, Selim Suner
Introduction Airway management is one of many challenges that medical providers face in disaster response operations. The use of personal protective equipment (PPE), in particular, was found to be associated with higher failure rates and a prolonged time to achieve airway control. Hypothesis/Problem The objective of this study was to determine whether video laryngoscopy could facilitate the performance of endotracheal intubation by disaster responders wearing Level C PPE. METHODS: In this prospective, randomized, crossover study, a convenience sample of practicing prehospital providers were recruited...
March 20, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28303774/physiological-evaluation-of-personal-protective-ensembles-recommended-for-use-in-west-africa
#2
Aitor Coca, Tyler Quinn, Jung-Hyun Kim, Tianzhou Wu, Jeff Powell, Raymond Roberge, Ronald Shaffer
OBJECTIVE: Personal protective equipment (PPE) provides health care workers with a barrier to prevent human contact with viruses like Ebola and potential transmission of the disease. However, PPE can also introduce an additional physiological burden from potentially increased heat stress. This study evaluated the human physiological and subjective responses to continuous light exercise within environmental conditions similar to those in West Africa while wearing 3 different, commonly used PPE ensembles (E1, E2, and E3)...
March 17, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28303772/physiological-evaluation-of-cooling-devices-in-conjunction-with-personal-protective-ensembles-recommended-for-use-in-west-africa
#3
Tyler Quinn, Jung-Hyun Kim, Amanda Strauch, Tianzhou Wu, Jeffery Powell, Raymond Roberge, Ronald Shaffer, Aitor Coca
OBJECTIVE: Cooling devices (CDs) worn under personal protective equipment (PPE) can alleviate some of the heat stress faced by health care workers responding to the Ebola outbreak in West Africa. METHODS: Six healthy, young individuals were tested while wearing 4 different CDs or no cooling (control) under PPE in an environmental chamber (32°C/92% relative humidity) while walking (3 METs, 2.5 mph, 0% grade) on a treadmill for 60 minutes. Exercise was preceded by a 15-minute stabilization period and a 15-minute donning period...
March 17, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28300048/cardiovascular-responses-to-millet-pounding-activity-among-women-in-a-rural-community-in-northeastern-nigeria
#4
Adetoyeje Y Oyeyemi, Fati Jajimaji, Adewale L Oyeyemi, Abdul-Hameed A Jabbo
BACKGROUND: Pounding food items in a wooden mortal is a common home chore in many communities in African and Asian countries. However, no empirical data exist on energy expenditure during this activity, and whether the activity can be considered a light, moderate, or vigorous intensity physical activity is unknown. PURPOSE: This study was aimed at gaining insights into energy expenditure during millet pounding through cardiovascular responses to millet pounding activity, and to explore possible differences in response between women who pound millet as their occupation (habitual millet pounders) and those who pound millet only for their own home cooking but not as a job (nonhabitual pounders)...
January 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28295336/neurochemistry-of-neurons-in-the-ventrolateral-medulla-activated-by-hypotension-are-the-same-neurons-activated-by-glucoprivation
#5
Lindsay M Parker, Sheng Le, Travis Wearne, Kate Hardwick, Natasha N Kumar, Katherine J Robinson, Simon McMullan, Ann K Goodchild
Previous studies have demonstrated that a range of stimuli activate neurons, including catecholaminergic neurons, in the ventrolateral medulla. Not all catecholaminergic neurons are activated and other neurochemical content is largely unknown hence whether stimulus specific populations exist is unclear. Here we determine the neurochemistry (using in situ hybridization) of catecholaminergic and non-catecholaminergic neurons which express c-Fos immunoreactivity throughout the rostrocaudal extent of the ventrolateral medulla, in Sprague Dawley rats treated with hydralazine or saline...
March 13, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28287681/the-preparticipation-physical-evaluation
#6
Patrick J Lehman, Rebecca L Carl
With rising rates of sports participation among children and adolescents, pediatricians are increasingly being called upon to perform preparticipation physical evaluations (PPEs) for young athletes. The purpose of this review article is to discuss the general structure of a comprehensive PPE and how the PPE differs from a typical health maintenance visit. The PPE focuses attention on screening for cardiac conditions that predispose athletes to sudden cardiac death with exercise. This review also addresses the debate over whether electrocardiogram screening should be a routine required part of the PPE...
March 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28277407/iron-deficiency-and-anemia-among-collegiate-athletes-a-retrospective-chart-review
#7
Rachel B Parks, Scott J Hetzel, M Alison Brooks
PURPOSE: To describe the prevalence of anemia among incoming female college athletes and to characterize the results and expenses of iron-related testing at one NCAA Division I institution. METHODS: In this retrospective medical record review, hemoglobin (Hgb) and ferritin (Fer) lab values were obtained for student-athletes at a single institution, 2002 - 2014. Labs were collected either as part of the pre-participation exam (PPE) for female athletes, routine screening for cross country athletes, or as needed for medical evaluation...
March 8, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28276185/temporal-and-spatial-variations-in-the-composition-of-freshwater-photosynthetic-picoeukaryotes-revealed-by-miseq-sequencing-from-flow-cytometry-sorted-samples
#8
Shengnan Li, Gisèle Bronner, Cécile Lepère, Fanxiang Kong, Xiaoli Shi
The diversity and composition of photosynthetic picoeukaryotes (PPEs) in two large shallow lakes in China (Lake Taihu and Lake Chaohu) were investigated from flow cytometry sorted samples using Miseq high-throughput sequencing. We collected 65 samples covering different regions of the two lakes over four seasons to unveil spatial and temporal patterns of PPEs community composition. The use of flow cytometry sorting largely improved the efficiency of detecting PPEs sequences and over 70% of the retrieved reads belonged to PPEs...
March 9, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28274866/application-of-fungal-chitosan-incorporated-with-pomegranate-peel-extract-as-edible-coating-for-microbiological-chemical-and-sensorial-quality-enhancement-of-nile-tilapia-fillets
#9
Mohammed S Alsaggaf, Shaaban H Moussa, Ahmed A Tayel
Fish are generous sources for providing man with his essential nutritional requirements, but the extreme susceptibility to quality deterioration hinders their optimal usage and storage. Natural derivatives are always the perfect alternatives for food preservation. The application of fungal chitosan (Ch), from Aspergillus niger, and pomegranate peel extract (PPE), in coating films for Nile tilapia (Oreochromis niloticus) fillets preservation ‎and maintaining their microbiological, chemical and sensorial quality during cooled storage at 4°C for 30days, was investigated...
March 6, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28273226/parapneumonic-pleural-effusion-reality-and-strategies-in-an-amazon-university-hospital
#10
Claudia Giselle Santos Arêas, Geraldo Roger Normando Júnior, Orlando Sandoval Farias Júnior, Irna Carla DO Rosário Souza Carneiro
OBJECTIVE: to define the profile and analyze the postoperative evolution of children with parapneumonic pleural effusion (PPE), and to evaluate strategies used in the presence of diagnostic and therapeutic limitations, emphasizing the open thoracic drainage (OTD) . METHODS: we conducted a cross-sectional, prospective, analytical study in which we followed children admitted in an Amazon university hospital with surgically addressed PPE, from October 2010 to October 2011...
December 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28260861/polyphosphoester-nanoparticles-as-biodegradable-platform-for-delivery-of-multiple-drugs-and-sirna
#11
Hadeel Elzeny, Fuwu Zhang, Esraa N Ali, Heba A Fathi, Shiyi Zhang, Richen Li, Mohamed A El-Mokhtar, Mostafa A Hamad, Karen L Wooley, Mahmoud Elsabahy
Delivery of multiple therapeutics and/or diagnostic agents to diseased tissues is challenging and necessitates the development of multifunctional platforms. Among the various strategies for design of multifunctional nanocarriers, biodegradable polyphosphoester (PPE) polymers have been recently synthesized via a rapid and simple synthetic strategy. In addition, the chemical structure of the polymer could be tuned to form nanoparticles with varying surface chemistries and charges, which have shown exceptional safety and biocompatibility as compared to several commercial agents...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28258110/planar-cell-polarity-effector-fritz-interacts-with-dishevelled-and-has-multiple-functions-in-regulating-pcp
#12
Ying Wang, Victor F Naturale, Paul N Adler
The Planar cell Polarity Effector (PPE) genes inturned, fuzzy and fritz are downstream components in the frizzled/starry night signaling pathway, and their function is instructed by upstream Planar Cell Polarity (PCP) core genes such as frizzled and disheveled PPE proteins accumulate asymmetrically in wing cells and function in a protein complex mediated by direct interactions between In and Frtz and In and Fy. How the PCP proteins instruct the accumulation of PPE protein is unknown. We found a likely direct interaction between Dishevelled and Fritz and Dishevelled and Fuzzy that could play a role in this...
March 3, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28253201/a-multiple-methods-approach-radiation-associated-cataracts-and-occupational-radiation-safety-practices-in-interventionalists-in-south-africa
#13
A Rose, W I D Rae, P Chikobvu, W Marais
Ionising radiation is a modality used in diagnostic and therapeutic medicine. The technology has improved and resulted in lower dose exposure but there has been an escalation in the quantity of procedures, their duration and complexity. These factors have meant increased occupational radiation exposure for interventionalists. Ionising radiation exposure can have detrimental health effects and includes radiation skin burns, various carcinomas, genetic and chromosomal aberrations and cataractogenesis of the lenses of the eye...
March 2, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28252824/patient-experiences-and-predictors-in-an-acute-geriatric-ward-a-cross-sectional-study
#14
Ann-Chatrin Linqvist Leonardsen, Lars-Petter Jelsness-Jørgensen
OBJECTIVE: To investigate older peoples' experiences with acute hospital treatment and care, and variables that may influence these experiences. BACKGROUND: In the Nordic countries, research on older peoples' experiences with hospital care is sparse. METHODS: Participants were recruited from an acute geriatric ward in a hospital in Norway during a one-year periode (n=189). Patient experience was assessed using the Picker Patient Experience Questionnaire (PPE-15), self-rated health by Euro-QoL 5-dimension, 3-level version (EQ-5D-3L), and comorbidity by Charlson comorbidity index (CCI)...
March 2, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28249677/factors-influencing-patient-experience-and-satisfaction-following-surgical-management-of-ankle-fractures
#15
Fiona Ashton, Khalid Hamid, Shazali Sulieman, William Eardley, Paul Baker
BACKGROUND: Patient feedback is increasingly important to inform and develop effective healthcare within the United Kingdom. In order to optimise patient experience of ankle fracture care in our unit, we sought to identify elements of practice associated with poor patient experience and low levels of satisfaction. METHODS: Adult patients with closed ankle fractures requiring fixation over a ten month period were prospectively identified. Prior to discharge all patients completed the Picker Patient Experience Questionnaire (PPE-15), satisfaction visual analogue scale (VAS: 0-10) and a demographic questionnaire...
February 22, 2017: Injury
https://www.readbyqxmd.com/read/28238589/vocal-loading-and-environmental-humidity-effects-in-older-adults
#16
Anusha Sundarrajan, Robert Brinton Fujiki, Sara E Loerch, Anumitha Venkatraman, M Preeti Sivasankar
The goal of this study was to investigate the effects of a vocal loading challenge that combined prolonged speaking, in child-directed voice within a noisy environment, in older adults. An additional goal was to determine whether increased environmental humidity would attenuate the negative effects of this vocal loading challenge. METHOD: Thirteen healthy subjects (five males and eight females; >65 years) completed a vocal loading challenge. The challenge involved 45 minutes of child-directed speech in the presence of 65 dB multitalker babble background noise...
February 23, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28225343/infection-control-and-tuberculosis-in-health-care-workers-an-assessment-of-28-hospitals-in-south-africa
#17
L M O'Hara, A Yassi, E A Bryce, A Janse van Rensburg, M C Engelbrecht, M Zungu, L E Nophale, J M FitzGerald
SETTING: Twenty-eight public hospitals in the Free State Province, South Africa. OBJECTIVE: To examine the association between tuberculosis (TB) infection control (IC) scores in Free State hospitals and the incidence of TB disease among health care workers (HCWs) in 2012. DESIGN: A cross-sectional survey and mixed-methods analysis of TB IC policies, practices and infrastructure using a comprehensive, 83-item IC audit and observation tool. RESULTS: As the total IC score increased, the probability of TB in an HCW at that hospital decreased...
March 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28223967/secretome-prediction-of-two-m-tuberculosis-clinical-isolates-reveals-their-high-antigenic-density-and-potential-drug-targets
#18
Fernanda Cornejo-Granados, Zyanya L Zatarain-Barrón, Vito A Cantu-Robles, Alfredo Mendoza-Vargas, Camilo Molina-Romero, Filiberto Sánchez, Luis Del Pozo-Yauner, Rogelio Hernández-Pando, Adrián Ochoa-Leyva
The Excreted/Secreted (ES) proteins play important roles during Mycobacterium tuberculosis invasion, virulence, and survival inside the host and they are a major source of immunogenic proteins. However, the molecular complexity of the bacillus cell wall has made difficult the experimental isolation of the total bacterial ES proteins. Here, we reported the genomes of two Beijing genotype M. tuberculosis clinical isolates obtained from patients from Vietnam (isolate 46) and South Africa (isolate 48). We developed a bioinformatics pipeline to predict their secretomes and observed that ~12% of the genome-encoded proteins are ES, being PE, PE-PGRS, and PPE the most abundant protein domains...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28220574/selective-use-of-the-electrocardiogram-in-pediatric-preparticipation-athletic-examinations-among-pediatric-primary-care-providers
#19
Bradley C Clark, Joshua M Hayman, Charles I Berul, Kristin M Burns, Jonathan R Kaltman
OBJECTIVES: Recent literature examining insurance administrative data suggests that a selective approach, with concurrent history and physical exam (H&P), for obtaining an electrocardiogram (ECG) as a part of a preparticipation examination (PPE) for pediatric athletes is commonly used in the primary care setting demonstrating a high rate of disease detection. We sought to understand practice patterns of providers with regard to usage of ECG as a part of PPE. METHODS: Utilizing an online survey, we queried primary care providers regarding their practice patterns, rationale, and concerns regarding use of ECGs as a part of the PPE...
February 21, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/28216628/genome-wide-primary-transcriptome-analysis-of-h2-producing-archaeon-thermococcus-onnurineus-na1
#20
Suhyung Cho, Min-Sik Kim, Yujin Jeong, Bo-Rahm Lee, Jung-Hyun Lee, Sung Gyun Kang, Byung-Kwan Cho
In spite of their pivotal roles in transcriptional and post-transcriptional processes, the regulatory elements of archaeal genomes are not yet fully understood. Here, we determine the primary transcriptome of the H2-producing archaeon Thermococcus onnurineus NA1. We identified 1,082 purine-rich transcription initiation sites along with well-conserved TATA box, A-rich B recognition element (BRE), and promoter proximal element (PPE) motif in promoter regions, a high pyrimidine nucleotide content (T/C) at the -1 position, and Shine-Dalgarno (SD) motifs (GGDGRD) in 5' untranslated regions (5' UTRs)...
February 20, 2017: Scientific Reports
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