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https://www.readbyqxmd.com/read/28343260/urethral-lumen-occlusion-by-artificial-sphincteric-devices-a-computational-biomechanics-approach
#1
Arturo Nicola Natali, Emanuele Luigi Carniel, Chiara Giulia Fontanella, Silvia Todros, Giulia Maria De Benedictis, Maria Angela Cerruto, Walter Artibani
The action induced by artificial sphincteric devices to provide urinary continence is related to the problem of evaluating the interaction between the occlusive cuff and the urethral duct. The intensity and distribution of the force induced within the region of application determine a different occlusion process and potential degradation of the urethral tissue, mostly at the borders of the cuff. This problem is generally considered in the light of clinical and surgical operational experience, while a valid cooperation is established with biomechanical competences by means of experimental and numerical investigation...
March 25, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28342799/lost-in-processing-perceived-healthfulness-taste-and-caloric-content-of-whole-and-processed-organic-food
#2
Marília Prada, Margarida V Garrido, David Rodrigues
The "organic" claim explicitly informs consumers about the food production method. Yet, based on this claim, people often infer unrelated food attributes. The current research examined whether the perceived advantage of organic over conventional food generalizes across different organic food types. Compared to whole organic foods, processed organic foods are less available, familiar and prototypical of the organic food category. In two studies (combined N = 258) we investigated how both organic foods types were perceived in healthfulness, taste and caloric content when compared to their conventional alternatives...
March 23, 2017: Appetite
https://www.readbyqxmd.com/read/28342504/retraction-notice-to-long-term-trends-1986-2003-in-the-use-of-coronary-reperfusion-strategies-in-patients-hospitalized-with-acute-myocardial-infarction-in-central-massachusetts-int-j-cardiol-131-2008-83-89
#3
Robert J Goldberg, Frederick A Spencer, Joseph Okolo, Darleen Lessard, Jorge Yarzebski, Joel M Gore
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief and Author. This article is a duplicate of a paper that has already been published in the Journal of Thrombosis and Thrombolysis, 23 (2007) 163-71. http://dx.doi.org/10.1007/s11239-006-9029-0. One of the conditions of submission of a paper for publication is that authors declare explicitly that the paper is not under consideration for publication elsewhere...
May 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28340220/her2-neu-status-determination-in-breast-cancer-a-single-institutional-experience-using-a-dual-testing-approach-with-immunohistochemistry-and-fluorescence-in-situ-hybridization
#4
James P Solomon, Marie Dell'Aquila, Oluwole Fadare, Farnaz Hasteh
Objectives: According to current guidelines, either immunohistochemistry (IHC) or in situ hybridization (ISH) can be used to determine human epidermal growth factor receptor 2 (Her2/neu) status in breast carcinoma. While the guidelines explicitly delineate result interpretation, there is no consensus on the most appropriate testing algorithm. Methods: The Her2/neu statuses of 369 consecutive cases of invasive breast cancer (from 351 patients) were assessed in a dual-testing algorithm that uses both IHC and fluorescence ISH (FISH)...
March 11, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28339783/a-stochastic-model-for-tumour-control-probability-that-accounts-for-repair-from-sublethal-damage
#5
Ana Victoria Ponce Bobadilla, Philip K Maini, Helen Byrne
The tumour control probability (TCP) is the probability that a treatment regimen of radiation therapy (RT) eradicates all tumour cells in a given tissue. To decrease the toxic effects on healthy cells, RT is usually delivered over a period of weeks in a series of fractions. This allows tumour cells to repair sublethal damage (RSD) caused by radiation. In this article, we introduce a stochastic model for tumour response to radiotherapy which accounts for the effects of RSD. The tumour is subdivided into two cell types: 'affected' cells which have been damaged by RT and 'unaffected' cells which have not...
February 26, 2017: Mathematical Medicine and Biology: a Journal of the IMA
https://www.readbyqxmd.com/read/28339479/mouse-newborn-cells-allow-highly-productive-mouse-cytomegalovirus-replication-constituting-a-novel-convenient-primary-cell-culture-system
#6
Vu Thuy Khanh Le-Trilling, Mirko Trilling
Mammalian cell culture is indispensable for most aspects of current biomedical research. Immortalized cell lines are very convenient, but transforming principles (e.g. oncogenic viruses or their oncogenes) can heavily influence the experimental outcome. Primary cells do not share this apparent disadvantage but are more laborious to generate. Certain viruses (e.g. mouse cytomegalovirus) do not replicate efficiently in most transformed cell lines. In the past, such viruses have been routinely propagated on primary mouse embryonic fibroblasts (MEF) established around day 17 (d17) of gestation...
2017: PloS One
https://www.readbyqxmd.com/read/28339461/mass-elevation-and-lee-effects-markedly-lift-the-elevational-distribution-of-ground-beetles-in-the-himalaya-tibet-orogen
#7
Joachim Schmidt, Jürgen Böhner, Roland Brandl, Lars Opgenoorth
Mass elevation and lee effects markedly influence snow lines and tree lines in high mountain systems. However, their impact on other phenomena or groups of organisms has not yet been quantified. Here we quantitatively studied their influence in the Himalaya-Tibet orogen on the distribution of ground beetles as model organisms, specifically whether the ground beetle distribution increases from the outer to the inner parts of the orogen, against latitudinal effects. We also tested whether July temperature and solar radiation are predictors of the beetle's elevational distribution ranges...
2017: PloS One
https://www.readbyqxmd.com/read/28339410/unimanual-versus-bimanual-therapy-in-children-with-unilateral-cerebral-palsy-same-same-but-different
#8
Brian Hoare, Susan Greaves
BACKGROUND: There is high-level evidence supporting constraint-induced movement therapy (CIMT) and bimanual therapy for children with unilateral cerebral palsy. Evidence-based intervention includes time-limited, goal-directed, skills-based, intensive blocks of practice based on motor learning theory. AIM AND METHODS: Using supporting literature and clinical insight, we provide a theoretical rationale to highlight previously unreported differences between CIMT and bimanual therapy...
2017: Journal of Pediatric Rehabilitation Medicine
https://www.readbyqxmd.com/read/28339266/spin-wave-excitations-evidencing-the-kitaev-interaction-in-single-crystalline-%C3%AE-rucl_-3
#9
Kejing Ran, Jinghui Wang, Wei Wang, Zhao-Yang Dong, Xiao Ren, Song Bao, Shichao Li, Zhen Ma, Yuan Gan, Youtian Zhang, J T Park, Guochu Deng, S Danilkin, Shun-Li Yu, Jian-Xin Li, Jinsheng Wen
Kitaev interactions underlying a quantum spin liquid have long been sought, but experimental data from which their strengths can be determined directly, are still lacking. Here, by carrying out inelastic neutron scattering measurements on high-quality single crystals of α-RuCl_{3}, we observe spin-wave spectra with a gap of ∼2  meV around the M point of the two-dimensional Brillouin zone. We derive an effective-spin model in the strong-coupling limit based on energy bands obtained from first-principles calculations, and find that the anisotropic Kitaev interaction K term and the isotropic antiferromagnetic off-diagonal exchange interaction Γ term are significantly larger than the Heisenberg exchange coupling J term...
March 10, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28338829/seeing-is-not-stereotyping-the-functional-independence-of-categorization-and-stereotype-activation
#10
Tiffany A Ito, Silvia Tomelleri
Social categorization has been viewed as necessarily resulting in stereotyping, yet extant research suggests the two processes are differentially sensitive to task manipulations. Here we simultaneously test the degree to which race perception and stereotyping are conditionally automatic. Participants performed a sequential priming task while either explicitly attending to the race of face primes or directing attention away from their semantic nature. We find a dissociation between the perceptual encoding of race and subsequent activation of associated stereotypes, with race perception occurring in both task conditions, but implicit stereotyping occurring only when attention is directed to the race of the face primes...
February 23, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28338664/characteristics-of-non-vitreoretinal-ocular-injury-in-child-maltreatment-a-systematic-review
#11
T Betts, S Ahmed, S Maguire, P Watts
PurposeTo identify the spectrum of non-vitreoretinal ocular injury due to child maltreatment.MethodsAll language search of MEDLINE, PsychINFO, EMBASE, AMED, Web of Science, and CINAHL databases, 1950-2015, was conducted. INCLUSION CRITERIA: explicit confirmation of injury aetiology, age <18 years, examination conducted by an ophthalmologist. Exclusion: post-mortem data, organic diseases, review articles. Standardised critical appraisal and narrative synthesis was conducted of included publications by two independent reviewers...
March 24, 2017: Eye
https://www.readbyqxmd.com/read/28338613/slum-upgrading-and-health-equity
#12
Jason Corburn, Alice Sverdlik
Informal settlement upgrading is widely recognized for enhancing shelter and promoting economic development, yet its potential to improve health equity is usually overlooked. Almost one in seven people on the planet are expected to reside in urban informal settlements, or slums, by 2030. Slum upgrading is the process of delivering place-based environmental and social improvements to the urban poor, including land tenure, housing, infrastructure, employment, health services and political and social inclusion...
March 24, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28338332/benchmark-ab-initio-characterization-of-the-complex-potential-energy-surface-of-the-f-ch3ch2cl-reaction
#13
Viktor Tajti, Gabor Czako
We compute benchmark structures, frequencies, and relative energies for the stationary points of the potential energy surface of the F- + CH3CH2Cl reaction using explicitly-correlated ab initio levels of theory. CCSD(T)-F12b geometries and harmonic vibrational frequencies are obtained with the aug-cc-pVTZ and aug-cc-pVDZ basis sets, respectively. The benchmark relative energies are determined using a high-level composite method based on CCSD(T)-F12b/aug-cc-pVQZ frozen-core energies, CCSD(T)-F12b/cc-pCVTZ-F12 core electron correlation effects, and CCSD(T)-F12b/aug-cc-pVDZ zero-point energy corrections...
March 24, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28337675/an-ontology-based-search-engine-for-digital-reconstructions-of-neuronal-morphology
#14
Sridevi Polavaram, Giorgio A Ascoli
Neuronal morphology is extremely diverse across and within animal species, developmental stages, brain regions, and cell types. This diversity is functionally important because neuronal structure strongly affects synaptic integration, spiking dynamics, and network connectivity. Digital reconstructions of axonal and dendritic arbors are thus essential to quantify and model information processing in the nervous system. NeuroMorpho.Org is an established repository containing tens of thousands of digitally reconstructed neurons shared by several hundred laboratories worldwide...
March 23, 2017: Brain Informatics
https://www.readbyqxmd.com/read/28337440/rabies-control-could-innovative-financing-break-the-deadlock
#15
REVIEW
Susan C Welburn, Paul G Coleman, Jakob Zinsstag
The neglected zoonotic diseases (NZDs) have been all but eradicated in wealthier countries but remain major causes of ill-health and mortality in over 80 countries across Africa, Asia, and Latin America. The nature of neglect for the NZDs has been ascribed, in part, to underreporting resulting in an underestimation of their global burden that, together with a lack of advocacy, downgrades their relevance to policy-makers and funding agencies. While this may be the case for many NZDs, for rabies this is not the case...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28336349/decisional-capacity-for-advanced-care-directives-in-parkinson-s-disease-with-cognitive-concerns
#16
Muneer Abu Snineh, Richard Camicioli, Janis M Miyasaki
INTRODUCTION: Physician Orders for Life Sustaining Therapies (POLST) or Goals of Care (GOC) are legal documents to guide intensity of interventions (ICU, resuscitation, hospitalization or comfort care) completed by healthcare professionals following counseling of patients or their designated medical decision makers. Capacity (understanding, appreciation, reasoning and expressing a choice) to consent to POLST or GOC has not been determined among Parkinson's disease (PD) patients. We sought to assess GOC PD decisional capacity for those with cognitive complaints but not dementia...
March 8, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28336109/multivitamin-mineral-supplements-rationale-and-safety
#17
REVIEW
Hans K Biesalski, Jana Tinz
Multivitamin/mineral supplements (MVMs) are widely used in many populations. MVMs, together with iron and folic acid, are recommended for pregnant women to improve birth outcome and to reduce low-birthweight and rates of miscarriage. However, MVM use is common in the general population as well. The aim of the present review was to evaluate the safety of long-term use of these supplements. To examine the safety of MVM use, we performed a literature search for randomized controlled studies involving supplementation with a combination of at least nine vitamins and three minerals at a maximum concentration of 100% of the Recommended Dietary Allowance...
April 2017: Nutrition
https://www.readbyqxmd.com/read/28335976/quantitative-determination-of-trace-hydrogen-peroxide-in-the-presence-of-sulfide-using-the-amplex-red-horseradish-peroxidase-assay
#18
Nannan Wang, Christopher J Miller, Peng Wang, T David Waite
The Amplex Red/horseradish peroxidase (AR/HRP) assay for H2O2 is one of the most sensitive and simple approaches for H2O2 quantification, which is effected by measuring the highly-fluorescent resorufin formed from oxidation of AR by the oxidizing intermediates generated by reaction of HRP and H2O2. The direct reactions of S(-II) with both H2O2 and resorufin are too slow to be of relevance on analytical timescales, however, the reaction between S(-II) and the HRP/H2O2 oxidizing intermediates is rapid enough to compete with the desired reaction of these oxidizing intermediates with AR, suppressing formation of the resorufin analyte...
April 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28335022/towards-local-implementation-of-dutch-health-policy-guidelines-a-concept-mapping-approach
#19
Theo J M Kuunders, Marja J H van Bon-Martens, Ien A M van de Goor, Theo G W M Paulussen, Hans A M van Oers
To develop a targeted implementation strategy for a municipal health policy guideline, implementation targets of two guideline users [Regional Health Services (RHSs)] and guideline developers of leading national health institutes were made explicit. Therefore, characteristics of successful implementation of the guideline were identified. Differences and similarities in perceptions of these characteristics between RHSs and developers were explored. Separate concept mapping procedures were executed in two RHSs, one with representatives from partner local health organizations and municipalities, the second with RHS members only...
February 22, 2017: Health Promotion International
https://www.readbyqxmd.com/read/28334586/processes-for-identifying-and-reviewing-adverse-events-and-near-misses-at-an-academic-medical-center
#20
William Martinez, Lisa Soleymani Lehmann, Yue-Yung Hu, Sonali Parekh Desai, Jo Shapiro
BACKGROUND: Conferences, processes, and/or meetings in which adverse events and near misses are reviewed within clinical programs at a single academic medical center were identified. METHODS: Leaders of conferences, processes, or meetings-"process leaders"-in which adverse events and near misses were reviewed were surveyed. RESULTS: On the basis of responses from all 45 process leaders, processes were classified into (1) Morbidity and Mortality Conferences (MMCs), (2) Quality Assurance (QA) Meetings, and (3) Educational Conferences...
January 2017: Joint Commission Journal on Quality and Patient Safety
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