keyword
MENU ▼
Read by QxMD icon Read
search

EBP

keyword
https://www.readbyqxmd.com/read/29457509/evidence-based-practice-self-efficacy-of-undergraduate-speech-pathology-students-following-training
#1
Maree Doble, Kate Short, Elizabeth Murray, Hans Bogaardt, Patricia McCabe
AIM: The aims of this study were to determine the self-efficacy of speech pathology students in conducting evidence-based practice before and after a comprehensive evidence-based practice course, and the impact of timing of the course (Semester 1/2). METHOD: Students attended a 13-week course in their final year of study. The evidence-based practice confidence scale (EPIC) was used to measure the students' self-efficacy pre- and post-training. RESULTS: Ninety-two percent of students enrolled over six semesters participated...
February 18, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29456896/factors-associated-with-elevated-blood-pressure-or-hypertension-in-afro-caribbean-youth-a-cross-sectional-study
#2
Trevor S Ferguson, Novie O M Younger-Coleman, Marshall K Tulloch-Reid, Nadia R Bennett, Amanda E Rousseau, Jennifer M Knight-Madden, Maureen E Samms-Vaughan, Deanna E Ashley, Rainford J Wilks
Background: Although several studies have identified risk factors for high blood pressure (BP), data from Afro-Caribbean populations are limited. Additionally, less is known about how putative risk factors operate in young adults and how social factors influence the risk of high BP. In this study, we estimated the relative risk for elevated BP or hypertension (EBP/HTN), defined as BP ≥ 120/80 mmHg, among young adults with putative cardiovascular disease (CVD) risk factors in Jamaica and evaluated whether relative risks differed by sex...
2018: PeerJ
https://www.readbyqxmd.com/read/29456653/metformin-protects-against-oxidized-low-density-lipoprotein-induced-macrophage-apoptosis-and-inhibits-lipid-uptake
#3
Ning Huangfu, Yong Wang, Jingsong Cheng, Zhenyu Xu, Shenghuang Wang
Oxidized low density lipoprotein (ox-LDL)-induced macrophage apoptosis contributes to the formation of atherosclerosis. Metformin, an antidiabetic drug, has been reported to attenuate lipid accumulation in macrophages. In this study, the effects of metformin on ox-LDL-induced macrophage apoptosis were investigated and the mechanisms involved in this process were examined. By performing flow cytometry analysis, it was demonstrated that metformin inhibited ox-LDL-induced macrophage apoptosis. Increased expression of endoplasmic reticulum (ER) stress marker proteins, including C/EBP-homologous protein, eukaryotic translation initiation factor 2A, and glucose-regulated protein 78 kDa, induced by ox-LDL was also reversed by metformin...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29454877/egyptian-and-jordanian-nurse-educators-perception-of-barriers-preventing-the-implementation-of-evidence-based-practice-a-cross-sectional-study
#4
Naglaa F A Youssef, Ali Alshraifeen, Karimeh Alnuaimi, Penney Upton
BACKGROUND: Studies discussing nurse educators' attitudes, knowledge/skills, practicing of evidence-based practice (EBP) and barriers encountered towards implementation is somewhat limited. OBJECTIVE: The study aimed to identify the attitudes, perceived knowledge/skills, and implementation of evidence-based as perceived by nurse educators, in Egyptian and Jordanian universities, and to assess factors preventing them from adopting it in nursing program. DESIGN/SETTING/RESPONDENTS/METHODS: A cross-sectional design was conducted including two groups from Egypt and Jordan...
February 10, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29454293/health-professions-faculty-beliefs-confidence-use-and-perceptions-of-organizational-culture-and-readiness-for-ebp-a-cross-sectional-descriptive-survey
#5
Kerry A Milner, Holly B Bradley, Tammy Lampley
BACKGROUND: Evidence-based practice (EBP) is an essential skill and ethical obligation for all practicing health professions clinicians because of its strong association with improved health outcomes. Emerging evidence suggests that faculty who prepare these clinicians lack proficiency to teach EBP. OBJECTIVES: The purpose of this study was to describe; 1) health profession faculty beliefs about and confidence in their ability to teach and implement EBP, 2) use of EBP for education, 3) organizational culture and readiness for EBP; and to determine whether relationships exist among these variables...
February 8, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/29450781/measuring-use-of-evidence-based-psychotherapy-for-posttraumatic-stress-disorder-in-a-large-national-healthcare-system
#6
Shira Maguen, Erin Madden, Olga V Patterson, Scott L DuVall, Lizabeth A Goldstein, Kristine Burkman, Brian Shiner
To derive a method of identifying use of evidence-based psychotherapy (EBP) for post-traumatic stress disorder (PTSD), we used clinical note text from national Veterans Health Administration (VHA) medical records. Using natural language processing, we developed machine-learning algorithms to classify note text on a large scale in an observational study of Iraq and Afghanistan veterans with PTSD and one post-deployment psychotherapy visit by 8/5/15 (N = 255,968). PTSD visits were linked to 8.1 million psychotherapy notes...
February 15, 2018: Administration and Policy in Mental Health
https://www.readbyqxmd.com/read/29448734/wear-resistance-properties-reinforcement-using-nano-al-cu-composite-coating-in-sliding-bearing-maintenance
#7
Hongtao Liu, Zhixiong Li, Jianmei Wang, Chenxing Sheng, Wanli Liu
Sliding bearing maintenance is crucial for reducing the cost and extending the service life. An efficient and practical solution is to coat a restorative agent onto the worn/damaged bearings. Traditional pure-copper (Cu) coating results in a soft surface and poor abrasion resistance. To address this issue, this paper presents a nano-composite repairing coating method. A series of nano-Al/Cu coatings were prepared on the surface of 45 steel by composite electro-brush plating (EBP). Their micro-hardness was examined by a MHV-2000 Vickers hardness tester, and tribological properties by a UMT-2M Micro-friction tester, 3D profiler and SEM...
March 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29448136/improving-functional-outcomes-in-women-with-borderline-personality-disorder-and-ptsd-by-changing-ptsd-severity-and-post-traumatic-cognitions
#8
Melanie S Harned, Chelsey R Wilks, Sara C Schmidt, Trevor N Coyle
Although functional impairment typically improves during evidence-based psychotherapies (EBPs) for borderline personality disorder (BPD), functional levels often remain suboptimal after treatment. The present pilot study evaluated whether and how integrating PTSD treatment into an EBP for BPD would improve functional outcomes. Participants were 26 women with BPD, PTSD, and recent suicidal and/or self-injurious behavior who were randomized to receive one year of Dialectical Behavior Therapy (DBT) or DBT with the DBT Prolonged Exposure (DBT PE) protocol for PTSD...
February 6, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29448105/casein-kinase-2-phosphorylates-and-stabilizes-c-ebp%C3%AE-in-pancreatic-%C3%AE-cells
#9
Tomoko Takai, Tomokazu Matsuda, Yuki Matsuura, Kaho Inoue, Emi Suzuki, Ayumi Kanno, Maki Kimura-Koyanagi, Shun-Ichiro Asahara, Naoya Hatano, Wataru Ogawa, Yoshiaki Kido
During the development of type 2 diabetes, endoplasmic reticulum (ER) stress leads to pancreatic β cell failure. CCAAT/enhancer-binding protein (C/EBP) β is highly induced by ER stress and AMP-activated protein kinase (AMPK) suppression in pancreatic β cells, and its accumulation reduces pancreatic β cell mass. We investigated the phosphorylation state of C/EBPβ under these conditions. Casein kinase 2 (CK2) was found to co-localize with C/EBPβ in MIN6 cells. It phosphorylated S222 of C/EBPβ, a previously unidentified phosphorylation site...
February 12, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29444179/capability-beliefs-on-and-use-of-evidence-based-practice-among-four-health-professional-and-student-groups-in-geriatric-care-a-cross-sectional-study
#10
Anne-Marie Boström, Disa K Sommerfeld, Annika W Stenhols, Anna Kiessling
Implementation of evidence-based practice (EBP) is a complex task. This study, conducted in an acute geriatric setting, aims to compare self-reported capability beliefs on EBP between health professionals and students, and to compare the use of EBP between health professional groups. Occupational therapists, physicians, physiotherapists and registered nurses with three or more months' employment, and all students from the occupational therapy, medical, physiotherapy and nursing programs, who had conducted workplace learning at the department, were invited...
2018: PloS One
https://www.readbyqxmd.com/read/29441719/azd1208-a-pan-pim-kinase-inhibitor-inhibits-adipogenesis-and-induces-lipolysis-in-3t3-l1-adipocytes
#11
Yu-Kyoung Park, Brice Wilfried Obiang-Obounou, Kyung-Bok Lee, Jong-Soon Choi, Byeong-Churl Jang
The proviral integration moloney murine leukaemia virus (Pim) kinases, consisting of Pim-1, Pim-2 and Pim-3, are involved in the control of cell growth, metabolism and differentiation. Pim kinases are emerging as important mediators of adipocyte differentiation. AZD1208 is a pan-Pim kinase inhibitor and is known for its anti-cancer activity. In this study, we investigated the effect of AZD1208 on adipogenesis and lipolysis in 3T3-L1 cells, a murine preadipocyte cell line. AZD1208 markedly suppressed lipid accumulation and reduced triglyceride contents in differentiating 3T3-L1 cells, suggesting the drug's anti-adipogenic effect...
February 14, 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29436479/the-ontogeny-of-a-neutrophil-mechanisms-of-granulopoiesis-and-homeostasis
#12
REVIEW
Shelley M Lawrence, Ross Corriden, Victor Nizet
Comprising the majority of leukocytes in humans, neutrophils are the first immune cells to respond to inflammatory or infectious etiologies and are crucial participants in the proper functioning of both innate and adaptive immune responses. From their initial appearance in the liver, thymus, and spleen at around the eighth week of human gestation to their generation in large numbers in the bone marrow at the end of term gestation, the differentiation of the pluripotent hematopoietic stem cell into a mature, segmented neutrophil is a highly controlled process where the transcriptional regulators C/EBP-α and C/EBP-ε play a vital role...
June 2018: Microbiology and Molecular Biology Reviews: MMBR
https://www.readbyqxmd.com/read/29433671/phytochemical-induced-reactive-oxygen-species-and-endoplasmic-reticulum-stress-mediated-apoptosis-and-differentiation-in-malignant-melanoma-cells
#13
Jae-Rim Heo, Geum-A Lee, Gyu-Sik Kim, Kyung-A Hwang, Kyung-Chul Choi
BACKGROUND: Phytochemicals are derived from plants, vegetables and daily products and exert chemopreventive effects. Malignant melanoma is highly metastatic, and melanoma patients can develop chemotherapeutic resistance against conventional melanoma therapies. METHODS: In the present study, we investigated the anti-cancer effect of the phytochemicals kaempferol (Kaem), genistein (Gen), and 3'3-diindolylmethane (DIM) on melanoma cell viability. We also evaluated the altered expression of cell cycle-related genes...
January 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29432397/attitudes-knowledge-and-behaviors-related-to-evidence-based-practice-in-health-professionals-involved-in-pain-management
#14
Vanitha Arumugam, Joy C MacDermid, Dave Walton, Ruby Grewal
BACKGROUND: Healthcare professionals involved in pain management come from different disciplines, which may have different perspectives and training about evidence-based practice (EBP). A common concern for health professionals is pain management. Understanding how different professions involved in pain management view EBP forms the ideal context to study professional differences in EPP, and how this might influence pain management. PURPOSE: The purpose of this study was to compare different professions with respect to knowledge, attitudes and self-reported behavior toward EBP...
February 8, 2018: International Journal of Evidence-based Healthcare
https://www.readbyqxmd.com/read/29429479/-chronic-post-dural-headache-secondary-to-meningitis
#15
Andreas Ravn, Louise Feldborg Lyckhage, Rigmor Høland Jensen
In this case report a young man was admitted with fever and headache, and a lumbar puncture revealed viral meningitis. After discharge, the patient experienced persistent headache, which worsened, when he was in upright position. The condition was considered secondary to the meningitis. After 14 months, the patient was diagnosed with post-dural puncture headache and treated with an epidural blood patch (EBP). The patient experienced no headache for three months, whereafter it returned. Subsequent EBP's were unsuccessful...
February 5, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29429180/-the-experimental-study-on-endoplasmic-reticulum-stress-participated-outer-hair-cell-apoptosis-in-cadherin-23-gene-mutant-mice
#16
J Hu, Z C Chen, Y Z Zhang, P Han, W J Ma, Q Zhang, M Xu
Objective: To test the mechanism and upstream pathway of outer hair cell apoptosis in Cadherin 23 (Cdh23) gene mutant mice. Method: The mutant Cdh23(erl/erl)(erl) mice were collected as the study group, while the C57BL/6J (B6) mice were chosen as the control group. A total of 70 mice per group were used in this study. The study group and control group underwent auditory-evoked brainstem response (ABR) tests at the same age. The terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay was performed to detect outer hair cell(OHC) apoptosis...
February 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29428758/the-unfolded-protein-response-is-involved-in-both-differentiation-and-apoptosis-of-bovine-mammary-epithelial-cells
#17
Shinichi Yonekura, Megumi Tsuchiya, Yukako Tokutake, Moeko Mizusawa, Miwa Nakano, Makoto Miyaji, Hiroshi Ishizaki, Satoshi Haga
The unfolded protein response (UPR) describes a process involved in the homeostasis of endoplasmic reticulum (ER) and the differentiation of secretory cells. At present, the roles of UPR in the mammary gland tissue of dairy cattle are unknown. In the current study, we investigated the expression of UPR-related genes in Holstein cows during the developmental and lactating stages of the mammary gland tissue. To investigate the roles of UPR during the differentiation of mammary epithelial cells (MEC), we used MAC-T cells, a line of MEC...
February 7, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29428092/detection-of-specific-bacterial-agents-by-quantitative-pcr-assays-in-the-bronchoalveolar-lavage-fluid-of-dogs-with-eosinophilic-bronchopneumopathy-vs-dogs-with-chronic-bronchitis-and-healthy-dogs
#18
A M Canonne, I Peters, E Roels, L Desquilbet, C Clercx
In humans, Mycoplasma pneumoniae and Bordetella pertussis infections are suggested to trigger or exacerbate asthma. Whether Mycoplasma or Bordetella are associated with chronic inflammatory bronchial diseases in dogs has not been investigated. The aim of this study was to assess detection rates of Mycoplasma canis (M. canis), M. cynos and Bordetella bronchiseptica (Bb), in dogs with eosinophilic bronchopneumopathy (EBP) and chronic bronchitis (CB), compared with healthy dogs. Specific quantitative PCR (qPCR) analysis for M...
February 2018: Veterinary Journal
https://www.readbyqxmd.com/read/29425932/ablation-of-c-ebp-homologous-protein-attenuates-renal-fibrosis-after-ureteral-obstruction-by-reducing-autophagy-and-microtubule-disruption
#19
Mi Ra Noh, Chang-Hoon Woo, Mae-Ja Park, Jee In Kim, Kwon Moo Park
Fibrosis is an undesirable consequence of injury and a critical problem in many diseases. Recent studies have demonstrated an association of C/EBP homologous protein (CHOP) with fibrosis. We investigated the mechanism of CHOP in kidney fibrosis progression after unilateral ureteral obstruction (UUO) using Chop gene-deleted (Chop-/-) mice and their wild-type littermates (Chop+/+). UUO-induced kidney fibrosis was reduced in the Chop-/- than Chop+/+ mice. After UUO, CHOP expression was detected in the cytosol and nucleus of distal tubule cells and collecting duct cells of the kidney...
February 6, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29424794/crocin-alleviates-myocardial-ischemia-reperfusion-induced-endoplasmic-reticulum-stress-via-regulation-of-mir-34a-sirt1-nrf2-pathway
#20
Xiaowu Wang, Binbin Yuan, Biao Cheng, Ying Liu, Ben Zhang, Xianyue Wang, Xi Lin, Bo Yang, Gu Gong
Endoplasmic reticulum (ER) stress is associated with ischemia/reperfusion (I/R)-induced cardiomyocyte apoptosis. Crocin could protect myocardial cells against I/R injury and suppress ER stress. This study aimed to explore the molecular mechanism of crocin related to ER stress in myocardial I/R injury. We found crocin alleviated I/R-induced cardiomyocyte apoptosis both in I/R-induced primary cardiomyocytes and in mouse models. The expression of Bax, active caspase 3, Glucose-regulated protein of 78 kDa (GRP78), and C/EBP homologous protein (CHOP) induced by I/R injury was reduced, whereas Bcl-2 expression was enhanced by crocin, the effect of which was abrogated by ER stress activator thapsigargin treatment...
February 8, 2018: Shock
keyword
keyword
38331
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"