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https://www.readbyqxmd.com/read/28716290/yarsagumba-fungus-health-problems-in-the-himalayan-gold-rush
#1
Pranawa Koirala, Bidur Pandit, Pratibha Phuyal, Ken Zafren
INTRODUCTION: Seasonal migration of people in search of Yarsagumba fungus creates a population of collectors that faces hardship and health risks in austere high-altitude settings. METHODS: In 2016, our 4-person team performed a 2-day health-needs survey of people collecting Yarsagumba fungus near the village of Yak Kharka (4020 m) in the Manang District of Nepal. RESULTS: There were approximately 800 people, both male and female, from age 10 to over 60, collecting Yarsagumba fungus...
July 14, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28711811/n-acetylcysteine-reduces-cocaine-cue-attentional-bias-and-differentially-alters-cocaine-self-administration-based-on-dosing-order
#2
B L Bolin, Joseph L Alcorn, Joshua A Lile, Craig R Rush, Abner O Rayapati, Lon R Hays, William W Stoops
BACKGROUND: Disrupted glutamate homeostasis is thought to contribute to cocaine-use disorder, in particular, by enhancing the incentive salience of cocaine stimuli. n-Acetylcysteine might be useful in cocaine-use disorder by normalizing glutamate function. In prior studies, n-acetylcysteine blocked the reinstatement of cocaine seeking in laboratory animals and reduced the salience of cocaine stimuli and delayed relapse in humans. METHODS: The present study determined the ability of maintenance on n-acetylcysteine (0 or 2400mg/day, counterbalanced) to reduce the incentive salience of cocaine stimuli, as measured by an attentional bias task, and attenuate intranasal cocaine self-administration (0, 30, and 60mg)...
June 29, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28707365/use-of-3-d-digital-subtraction-rotational-angiography-during-cardiac-catheterization-of-infants-and-adults-with-congenital-heart-diseases
#3
Sushitha Surendran, B Rush Waller, Lucas Elijovich, Vijaykumar Agrawal, Andrew Kuhls-Gilcrist, Jason Johnson, Thomas Fagan, Shyam K Sathanandam
OBJECTIVE: To compare image quality, radiation and contrast doses required to obtain 3D-Digital subtraction rotational angiography (3D-DSRA) with 3D-Digital rotational angiography (3D-DRA) in infants (children ≤ 2 years of age) and adults with congenital heart diseases (ACHD). BACKGROUND: 3D-DRA can be performed with radiation doses comparable to bi-plane cine-angiography. However, 3D-DRA in infants requires a large contrast volume. The resolution of 3D-DRA performed in ACHD patients is limited by their soft tissue density...
July 14, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28706538/safety-of-100%C3%A2-%C3%A2%C2%B5g-venom-immunotherapy-rush-protocols-in-children-compared-to-adults
#4
Johanna Stoevesandt, Christine Hosp, Andreas Kerstan, Axel Trautmann
BACKGROUND: There is a paucity of studies examining the safety of venom immunotherapy (VIT) in children. We aimed to assess the incidence of anaphylactic side effects during rush VIT in a cohort of pediatric patients and adult controls. METHODS: 72 consecutive cycles of VIT-buildup in 71 children/adolescents aged 7-17 years were retrospectively evaluated and compared to an adult control group (n = 981) with regard to baseline parameters (sex, causative venom, severity of index sting reaction, results of allergy testing, comorbidities) and the incidence of anaphylactic adverse reactions...
2017: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/28699453/hardship
#5
(no author information available yet)
A nurse who rushed to treat people during the Grenfell Tower fire has spoken of her struggle to pay bills.
July 12, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28695971/transfusion-requirements-following-total-knee-arthroplasty-in-patients-with-preexisting-blood-dyscrasia
#6
Martin Roche, Tsun Yee Law, Samuel Rosas, Augustus J Rush, Anton Khlopas, Morad Chughtai, Michael A Mont
INTRODUCTION: There is a paucity of studies investigating the incidence of transfusions in various blood dyscrasias after total knee arthroplasty (TKA). The purpose of this study was: 1) to compare the incidence of transfusion post-TKA in patients with and without blood dyscrasia; 2) to compare the post-TKA transfusion incidence of patients with the various individual blood dyscrasias; and 3) to stratify the findings based on gender and age. MATERIALS AND METHODS: A retrospective review of a Medicare database for patients with preexisting blood dyscrasia was conducted...
July 11, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28694550/children-s-experiences-of-time-when-a-parent-travels-for-work
#7
Anisa Zvonkovic, Andrea Swenson, Zoë Cornwell
This qualitative study focuses on different ways time is experienced by children in families who face time challenges due to a family member's job that required work travel. Data are from a family-level study that includes interviews of all family members over the age of 7. Using grounded theory methodology, this study illustrates ways in which job demands and family processes interact. Analysis centers on the 75 children's perspectives from 43 families. Holding together assessments of having enough time while wanting more time with their parents, children express emotion, generally unrecognized by parents, around the topic of family time...
August 2017: Journal of Marriage and the Family
https://www.readbyqxmd.com/read/28686621/risk-of-bias-and-confounding-of-observational-studies-of-zika-virus-infection-a-scoping-review-of-research-protocols
#8
Ludovic Reveiz, Michelle M Haby, Ruth Martínez-Vega, Carlos E Pinzón-Flores, Vanessa Elias, Emma Smith, Mariona Pinart, Nathalie Broutet, Francisco Becerra-Posada, Sylvain Aldighieri, Maria D Van Kerkhove
INTRODUCTION: Given the severity and impact of the current Zika virus (ZIKV) outbreak in the Americas, numerous countries have rushed to develop research studies to assess ZIKV and its potential health consequences. In an effort to ensure that studies are comprehensive, both internally and externally valid, and with reliable results, the World Health Organization, the Pan American Health Organization, Institut Pasteur, the networks of Fiocruz, the Consortia for the Standardization of Influenza Seroepidemiology (CONSISE) and the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) have generated six standardized clinical and epidemiological research protocols and questionnaires to address key public health questions on ZIKV...
2017: PloS One
https://www.readbyqxmd.com/read/28682456/how-hospital-clinicians-select-patients-for-skilled-nursing-facilities
#9
Robert E Burke, Emily Lawrence, Amy Ladebue, Roman Ayele, Brandi Lippmann, Ethan Cumbler, Rebecca Allyn, Jacqueline Jones
OBJECTIVE: To understand how hospital-based clinicians evaluate older adults in the hospital and decide who will be transferred to a skilled nursing facility (SNF) for postacute care. DESIGN: Semistructured interviews paired with a qualitative analytical approach informed by Social Constructivist theory. SETTING: Inpatient care units in three hospitals. Purposive sampling was used to maximize variability in hospitals, units within hospitals, and staff on those units...
July 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28682444/selecting-a-skilled-nursing-facility-for-postacute-care-individual-and-family-perspectives
#10
Emily A Gadbois, Denise A Tyler, Vincent Mor
OBJECTIVES: To describe individuals' experiences during the hospital discharge planning and skilled nursing facility (SNF) selection process. DESIGN: Semistructured interviews focusing on discharge planning and nursing facility selection, including how facilities were chosen, who was involved, and what factors were important in decision-making. SETTING: 14 SNFs in five cities across the United States. PARTICIPANTS: Newly admitted, previously community-dwelling SNF residents (N = 98) and their family members...
July 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28681291/time-resolved-monitoring-of-polycyclic-aromatic-hydrocarbons-adsorbed-on-atmospheric-particles
#11
Gustavo Sousa, Denis Kiselev, Jérôme Kasparian, Christian George, José Ferreira, Philippe Favreau, Benoît Lazzarotto, Jean-Pierre Wolf
Real-time monitoring of individual particles from atmospheric aerosols was performed by means of a specifically developed single-particle fluorescence spectrometer (SPFS). The observed fluorescence was assigned to particles bearing polycyclic aromatic hydrocarbons (PAH). This assignment was supported by an intercomparison with classical speciation on filters followed by gas chromatography-mass spectrometry (GC-MS) analysis. As compared with daily averaged data, our time-resolved approach provided information about the physicochemical dynamics of the particles...
July 5, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28672073/prediction-of-treatment-outcomes-to-exercise-in-patients-with-nonremitted-major-depressive-disorder
#12
Chad D Rethorst, Charles C South, A John Rush, Tracy L Greer, Madhukar H Trivedi
BACKGROUND: Only one-third of patients with major depressive disorder (MDD) achieve remission with initial treatment. Consequently, current clinical practice relies on a "trial-and-error" approach to identify an effective treatment for each patient. The purpose of this report was to determine whether we could identify a set of clinical and biological parameters with potential clinical utility for prescription of exercise for treatment of MDD in a secondary analysis of the Treatment with Exercise Augmentation in Depression (TREAD) trial...
July 3, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28671928/examiner-handedness-and-the-effects-on-intraocular-pressure-readings-using-the-tono-pen-xl
#13
Alexander G Hacopian, Lauren C Rushing, Alice Z Chuang, Nicholas P Bell, Kartik S Kumar, Robert M Feldman
PURPOSE: To assess the effect of examiner handedness on intraocular pressure (IOP) readings using the Tono-Pen XL in eyes without corneal pathology or previous ocular surgeries. PATIENTS AND METHODS: Patients 18 years of age or older were included in this prospective study. Participants who had a history of corneal conditions or other characteristics that would prevent reliable IOP measurements were excluded. Five experienced examiners, 2 right-hand dominant and 3 left-hand dominant, took bilateral IOP measurements with a Tono-Pen XL...
June 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28668111/a-10-year-experience-of-a-novel-and-safe-modified-environmental-rush-immunotherapy-protocol
#14
Merritt L Fajt, Stacy L Rosenberg, Emmanuelle Yecies, Russell S Traister, Andrej A Petrov
BACKGROUND: Allergen immunotherapy (AIT) is an effective treatment option for allergic rhinitis. Although conventional AIT takes 6 months to reach maintenance dosing, rush AIT accelerates the build-up period and reaches the maintenance dose months earlier. However, accelerated schedules of AIT carry an increased risk of systemic reactions (SR). OBJECTIVE: We aimed to describe a novel 1-day, eight-step modified environmental rush immunotherapy (MERIT) protocol, characteristics of the patients who underwent this therapy, and the safety of this procedure...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28662750/viral-vector-biosafety-in-laboratory-animal-research
#15
Dalis E Collins, Jon D Reuter, Howard G Rush, Jason S Villano
Viral vector research presents unique occupational health and safety challenges to institutions due to the rapid development of both in vivo and in vitro gene-editing technologies. Risks to human and animal health make it incumbent on institutions to appropriately evaluate viral vector usage in research on the basis of available information and governmental regulations and guidelines. Here we review the factors related to risk assessment regarding viral vector usage in animals and the relevant regulatory documents associated with this research, and we highlight the most commonly used viral vectors in research today...
June 1, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28660622/palliative-care-access-for-hospitalized-patients-with-end-stage-liver-disease-across-the-united-states
#16
Barret Rush, Keith R Walley, Leo Anthony Celi, Neil Rajoriya, Mayur Brahmania
OBJECTIVE: Patients with end-stage liver disease (ESLD) often have a high symptom burden. Historically, palliative care (PC) services have been underutilized in this population. We investigated the use of PC services in patients with ESLD hospitalized across the United States. METHODS: We utilized the Nationwide Inpatient Sample (NIS) to conduct a retrospective nationwide cohort analysis. All patients >18 years of age admitted with ESLD, defined as those with at least two liver decompensation events, were included in the analysis...
June 29, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28656843/processing-tragedy-the-aftermath-of-grenfell-tower
#17
Erin Dean
Palliative care nurse Simone Williams was woken by sirens on the night of the fire at nearby Grenfell Tower and rushed out to see what was happening. She helped look after those who had escaped from the burning building and knocked on doors appealing for blankets for them.
June 28, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28655174/diagnosis-and-management-of-osteopetrosis-consensus-guidelines-from-the-osteopetrosis-working-group
#18
Calvin C Wu, Michael J Econs, Linda A DiMeglio, Karl L Insogna, Michael A Levine, Paul J Orchard, Weston P Miller, Anna Petryk, Eric T Rush, Dolores M Shoback, Leanne M Ward, Lynda E Polgreen
Background: Osteopetrosis encompasses a group of rare metabolic bone diseases characterized by impaired osteoclast activity or development, resulting in high bone mineral density. Existing guidelines focus on treatment of the severe infantile forms with hematopoietic cell transplantation (HCT), but do not address the management of patients with less severe forms for whom HCT is not the standard of care. Therefore, our objective was to develop expert consensus guidelines that would address the management of these patients...
June 26, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28651804/efficacy-and-safety-of-trabectedin-or-dacarbazine-in-patients-with-advanced-uterine-leiomyosarcoma-after-failure-of-anthracycline-based-chemotherapy-subgroup-analysis-of-a-phase-3-randomized-clinical-trial
#19
Martee L Hensley, Shreyaskumar R Patel, Margaret von Mehren, Kristen Ganjoo, Robin L Jones, Arthur Staddon, Daniel Rushing, Mohammed Milhem, Bradley Monk, George Wang, Sharon McCarthy, Roland E Knoblauch, Trilok V Parekh, Robert G Maki, George D Demetri
OBJECTIVE: Trabectedin demonstrated significantly improved disease control in leiomyosarcoma and liposarcoma patients in a global phase 3 trial (NCT01343277). A post hoc analysis was conducted to assess the efficacy and safety of trabectedin or dacarbazine in women with uterine leiomyosarcoma (uLMS), the largest subgroup of enrolled patients (40%). METHODS: Of 577 patients randomized 2:1 to receive trabectedin 1.5mg/m(2) by 24-hour IV infusion or dacarbazine 1g/m(2) by 20-120-minute IV infusion once every three weeks, 232 had uLMS (trabectedin: 144; dacarbazine: 88)...
June 23, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28649041/determination-of-the-vertical-profile-of-particle-number-concentration-adjacent-to-a-motorway-using-an-unmanned-aerial-vehicle
#20
T F Villa, E R Jayaratne, L F Gonzalez, L Morawska
A quantitative assessment of the vertical profile of traffic pollution, specifically particle number concentration (PNC), in an open space adjacent to a motorway was possible for the first time, to the knowledge of the authors, using an Unmanned Aerial Vehicle (UAV) system. Until now, traffic pollution has only been measured at ground level while the vertical distribution, is limited to studies conducted from buildings or fixed towers and balloons. This new UAV system demonstrated that the PNC sampled during the period form 10 a...
June 22, 2017: Environmental Pollution
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