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https://www.readbyqxmd.com/read/28424541/physician-s-recommendation-and-explanation-is-important-in-the-initiation-and-maintenance-of-allergen-immunotherapy
#1
Young-Hee Nam, Soo-Keol Lee
BACKGROUND: Allergen immunotherapy (AIT) is currently the only immune-modifying treatment for allergic disease. The clinical efficacy of AIT for the treatment of allergic rhinitis and bronchial asthma is well documented. However, many factors including inconvenience, cost, side effects, and adherence influence the initiation and persistence of AIT, and patients lack knowledge and have misconceptions about the treatment. OBJECTIVE: We evaluated the knowledge, attitude, and satisfaction of patients who received AIT...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28419904/leydig-cell-tumor-in-grey-zone-a-case-report
#2
Muheilan Mustafa Muheilan, Maha Shomaf, Emad Tarawneh, Muayyad Mujalli Murshidi, Manar Rizik Al-Sayyed, Mujalli Mhailan Murshidi
INTRODUCTION: Leydig cell tumor constitutes only about 1-3% of testicular neoplasms. There is apparently increased incidence in the last few years; one possible explanation for this phenomenon is the widespread use of ultrasound technology and the subsequent increased early detection of smaller lesions that have not been found in historical series. CASE PRESENTATION: We report a case of Leydig cell tumor of testis in a patient presenting with painless long standing slowly growing left scrotal mass who found to have intrapulmonary nodule and multiple enlarged retroperitoneal lymph nodes on staging work up...
April 4, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28418830/increased-neurotropic-threat-from-burkholderia-pseudomallei-strains-with-a-b-mallei-like-variation-in-the-bima-motility-gene-australia
#3
Jodie L Morris, Anne Fane, Derek S Sarovich, Erin P Price, Catherine M Rush, Brenda L Govan, Elizabeth Parker, Mark Mayo, Bart J Currie, Natkunam Ketheesan
Neurologic melioidosis is a serious, potentially fatal form of Burkholderia pseudomallei infection. Recently, we reported that a subset of clinical isolates of B. pseudomallei from Australia have heightened virulence and potential for dissemination to the central nervous system. In this study, we demonstrate that this subset has a B. mallei-like sequence variation of the actin-based motility gene, bimA. Compared with B. pseudomallei isolates having typical bimA alleles, isolates that contain the B. mallei-like variation demonstrate increased persistence in phagocytic cells and increased virulence with rapid systemic dissemination and replication within multiple tissues, including the brain and spinal cord, in an experimental model...
May 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28410639/socioeconomic-status-not-race-is-associated-with-reduced-survival-in-esophagectomy-patients
#4
Loretta Erhunmwunsee, Brian C Gulack, Christel Rushing, Donna Niedzwiecki, Mark F Berry, Matthew G Hartwig
BACKGROUND: Black patients with esophageal cancer have worse survival than white patients. This study examines this racial disparity in conjunction with socioeconomic status (SES) and explores whether race-based outcome differences exist using a national database. METHODS: The associations between race and SES with overall survival of patients treated with esophagectomy for stages I to III esophageal cancer between 2003 and 2011 in the National Cancer Data Base were investigated using the Kaplan-Meier method and proportional hazards analyses...
April 12, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28403770/adaptation-of-a-biobank-certification-program-for-australia
#5
Jane E Carpenter, Amanda Rush, Candace Carter
No abstract text is available yet for this article.
April 17, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28402267/contrast-enhanced-ultrasound-evaluation-of-pancreatic-cancer-xenografts-in-nude-mice-after-irradiation-with-sub-threshold-focused-ultrasound-for-tumor-ablation
#6
Yi Hui Gao, Lei Wu, Rui Wang, Qian Guo, Yi Ni Chen, Bing Hu, Li Xin Jiang
We evaluated the efficacy of contrast-enhanced ultrasound for assessing tumors after irradiation with sub-threshold focused ultrasound (FUS) ablation in pancreatic cancer xenografts in nude mice. Thirty tumor-bearing nude mice were divided into three groups: Group A received sham irradiation, Group B received a moderate-acoustic energy dose (sub-threshold), and Group C received a high-acoustic energy dose. In Group B, B-mode ultrasound (US), color Doppler US, and dynamic contrast-enhanced ultrasound (DCE-US) studies were conducted before and after irradiation...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28400247/quality-of-life-dyspnea-and-functional-exercise-capacity-following-a-first-episode-of-pulmonary-embolism-results-of-the-elope-cohort-study
#7
Susan R Kahn, Arash Akaberi, John T Granton, David R Anderson, Philip S Wells, Marc A Rodger, Susan Solymoss, Michael J Kovacs, Lawrence Rudski, Avi Shimony, Carole Dennie, Chris Rush, Paul Hernandez, Shawn D Aaron, Andrew M Hirsch
BACKGROUND: We aimed to evaluate health-related quality of life (QOL), dyspnea and functional exercise capacity during the year following the diagnosis of a first episode of pulmonary embolism. METHODS: Prospective multicenter cohort study of 100 patients with acute pulmonary embolism recruited at 5 Canadian hospitals from 2010-2013. We measured the outcomes QOL (by SF-36 and PEmb-QOL measures), dyspnea (by the University of California San Diego Shortness of Breath Questionnaire (SOBQ)) and six-minute walk distance at Baseline, 1, 3, 6, and 12 months after acute pulmonary embolism...
April 8, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28398941/the-season-of-hoverboards-a-case-series-of-fractures
#8
Chester J Donnally, Charles M Lawrie, Augustus J Rush, Avi C Baitner
OBJECTIVE: The aim of this study was to identify the types of pediatric orthopedic extremity fractures that are sustained as a result of hoverboard (self-balancing, self-propelling, 2-wheeled boards) use. METHODS: We performed a retrospective review of all orthopedic consultations from the emergency department at our institution from December 1 to 31, 2015. Data was collected on the injury mechanism, fracture location, management, and patient characteristics including sex, age, and hand dominance...
April 11, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28397379/b-fahf-2-plus-oral-immunotherapy-oit-is-safer-and-more-effective-than-oit-alone-in-a-murine-model-of-concurrent-peanut-tree-nut-allergy
#9
Kamal D Srivastava, Ying Song, Nan Yang, Changda Liu, Ilan E Goldberg, Anna Nowak-Węgrzyn, Hugh A Sampson, Xiu-Min Li
BACKGROUND: Concurrent sensitization to peanut (PN) and tree nuts (TN), the most dangerous food allergies, is common. Current oral immunotherapy (OIT) is not fully satisfactory. OBJECTIVE: To determine if the herbal formula B-FAHF-2 (BF2) ameliorates PN/TN OIT adverse reactions and enhances persistence of a tolerant state. METHODS: Concurrently sensitized peanut, walnut (WN) and cashew (CSH) allergic mice received 1 day PN/WN/CSH rush OIT plus 3 weeks of maintenance dosing, with or without 3-weeks prior and 3-weeks BF2 co-treatment...
April 11, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28392928/cost-of-intervention-delivery-in-a-lifestyle-weight-loss-trial-in-type-2-diabetes-results-from-the-look-ahead-clinical-trial
#10
J Rushing, R Wing, T A Wadden, W C Knowler, M Lawlor, M Evans, T Killean, M Montez, M A Espeland, P Zhang
OBJECTIVE: The Action for Health in Diabetes (Look AHEAD) trial was a randomized controlled clinical trial to compare the effects of 10 years of intensive lifestyle intervention (ILI) with a control condition of diabetes support and education (DSE) on health outcomes in over 5,000 participants with type 2 diabetes. The ILI had significantly greater weight losses than DSE throughout the trial. The goal of this analysis is to describe the cost of delivering the intervention. METHODS: The ILI was designed to promote weight loss and increase physical activity...
March 2017: Obesity Science & Practice
https://www.readbyqxmd.com/read/28391367/an-updated-meta-analysis-of-the-ego-depletion-effect
#11
REVIEW
Junhua Dang
The ego depletion effect is one of the most famous phenomena in social psychology. A recent meta-analysis showed that after accounting for small-studies effects by using a newly developed method called PET-PEESE, the ego depletion effect was indistinguishable from zero. However, it is too early to draw such rushing conclusion because of the inappropriate usage of PET-PEESE. The current paper reported a stricter and updated meta-analysis of ego depletion by carefully inspecting problems in the previous meta-analysis, including new studies not covered by it, and testing the effectiveness of each depleting task...
April 8, 2017: Psychological Research
https://www.readbyqxmd.com/read/28385107/association-of-household-income-level-and-in-hospital-mortality-in-patients-with-sepsis-a-nationwide-retrospective-cohort-analysis
#12
Barret Rush, Katie Wiskar, Leo Anthony Celi, Keith R Walley, James A Russell, Robert C McDermid, John H Boyd
OBJECTIVE: Associations between low socioeconomic status (SES) and poor health outcomes have been demonstrated in a variety of conditions. However, the relationship in patients with sepsis is not well described. We investigated the association of lower household income with in-hospital mortality in patients with sepsis across the United States. METHODS: Retrospective nationwide cohort analysis utilizing the Nationwide Inpatient Sample (NIS) from 2011. Patients aged 18 years or older with sepsis were included...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28378769/aipl1-is-required-for-cone-photoreceptor-function-and-survival-through-the-stability-of-pde6c-and-gc3-in-zebrafish
#13
Maria Iribarne, Yuko Nishiwaki, Shohei Nakamura, Masato Araragi, Eri Oguri, Ichiro Masai
Genetic mutations in aryl hydrocarbon receptor interacting protein-like 1 (AIPL1) cause photoreceptor degeneration associated with Leber congenital amaurosis 4 (LCA4) in human patients. Here we report retinal phenotypes of a zebrafish aipl1 mutant, gold rush (gosh). In zebrafish, there are two aipl1 genes, aipl1a and aipl1b, which are expressed mainly in rods and cones, respectively. The gosh mutant gene encodes cone-specific aipl1, aipl1b. Cone photoreceptors undergo progressive degeneration in the gosh mutant, indicating that aipl1b is required for cone survival...
April 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28378650/nursingstandard-com
#14
(no author information available yet)
1 Nurses who rushed to help victims of the attack in Westminster have been praised for their bravery and professionalism. Read more: rcni.com/Westminster-attack.
April 5, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28376212/durable-control-of-metastatic-akt1-mutant-who-grade-1-meningothelial-meningioma-by-the-akt-inhibitor-azd5363
#15
Michael Weller, Patrick Roth, Felix Sahm, Isabel Burghardt, Bernhard Schuknecht, Elisabeth J Rushing, Luca Regli, Justin P Lindemann, Andreas von Deimling
High-throughput analyses have revealed the presence of activating mutations in the AKT1 gene in a subpopulation of meningiomas. We report a female patient with multiple intracranial tumor manifestations and histologically verified meningotheliomatous meningioma in the lung. The tumor was continuously growing at multiple sites despite six surgical resections, radiotherapy, and two lines of systemic therapy. Following detection of an AKT1E17K mutation in three independent tumor samples by sequencing, treatment with AZD5363, a selective AKT inhibitor, was initiated...
March 1, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28375598/reassessment-of-the-upper-fremont-glacier-ice-core-chronologies-by-synchronizing-of-ice-core-water-isotopes-to-a-nearby-tree-ring-chronology
#16
Nathan Chellman, Joseph R McConnell, Monica Arienzo, Gregory T Pederson, Sarah M Aarons, Adam Csank
The Upper Fremont Glacier (UFG), Wyoming, is one of the few continental glaciers in the contiguous United States known to preserve environmental and climate records spanning recent centuries. A pair of ice cores taken from UFG have been studied extensively to document changes in climate and industrial pollution (most notably, mid-19th century increases in mercury pollution). Fundamental to these studies is the chronology used to map ice-core depth to age. Here, we present a revised chronology for the UFG ice cores based on new measurements and using a novel dating approach of synchronizing continuous water isotope measurements to a nearby tree-ring chronology...
April 4, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28370373/association-between-survival-time-and-changes-in-nt-probnp-in-cats-treated-for-congestive-heart-failure
#17
K V Pierce, J E Rush, L M Freeman, S M Cunningham, V K Yang
BACKGROUND: Reductions in N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations after treatment have been associated with improved survival in people with congestive heart failure (CHF), but have not been reported in cats with CHF. OBJECTIVES: To evaluate changes in NT-proBNP concentrations in cats with CHF after treatment and determine whether serial NT-proBNP measurements provide prognostic information. ANIMALS: Thirty-one client-owned cats...
March 31, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28368718/examining-the-validity-of-the-rush-protocol-to-screen-for-religious-spiritual-struggle
#18
George Fitchett, Patricia Murphy, Stephen D W King
Effective deployment of limited spiritual care resources requires valid and reliable methods of screening that can be used by nonchaplain health care professionals to identify and refer patients with potential religious/spiritual (R/S) need. Research regarding the validity of existing approaches to R/S screening is limited. In a sample of 1,399 hematopoietic stem cell transplant survivors, we tested the validity of the Rush Protocol and two alternative versions of it. The negative religious coping subscale of the Brief RCOPE provided the reference standard...
April 3, 2017: Journal of Health Care Chaplaincy
https://www.readbyqxmd.com/read/28367204/effectiveness-of-media-awareness-campaigns-on-the-proportion-of-vehicles-that-give-space-to-ambulances-on-roads-an-observational-study
#19
Shiraz Shaikh, Lubna A Baig, Maciej Polkowski
BACKGROUND AND OBJECTIVE: The findings of the Health Care in Danger project in Karachi suggests that there is presence of behavioral negligence among vehicle operators on roads in regards to giving way to ambulances. A mass media campaign was conducted to raise people's awareness on the importance of giving way to ambulances. The main objective of this study was to determine the effectiveness of the campaign on increasing the proportion of vehicles that give way to ambulances. METHODS: This was a quasi-experimental study that was based on before and after design...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28367160/neural-stem-cell-heterogeneity-through-time-and-space-in-the-ventricular-subventricular-zone
#20
Gabrielle Rushing, Rebecca A Ihrie
BACKGROUND: The origin and classification of neural stem cells (NSCs) has been a subject of intense investigation for the past two decades. Efforts to categorize NSCs based on their location, function and expression have established that these cells are a heterogeneous pool in both the embryonic and adult brain. The discovery and additional characterization of adult NSCs has introduced the possibility of using these cells as a source for neuronal and glial replacement following injury or disease...
August 2016: Frontiers in Biology
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