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Beibei Hu, Yawen Kong, Mengge Sun, Xianlei Dong, Gang Zong
Nowadays, ride-hailing services have been established as a part of the urban transportation. Their arrival has remade the profit structure and resulted in the unbalance of interest in taxi market. Here, we establish the service models of taxis, carpooling, and car-hailing under "Internet +" from the perspective of profit margins, to perform a comparative analysis among the different services. RESULTS: First, Profit margins are generally higher for short trips than for long trips, though empty cruise fee to a certain degree make up for the driver's decreased profit margins...
2018: PloS One
Patrick Donnelly Tyler, Barret Rush, Leo A Celi
No abstract text is available yet for this article.
July 2018: Critical Care Medicine
Stefano Pucci, Fedra Ciccarelli, Tiziana De Pasquale, Ilenia Illuminati, Simona D'Alò
No abstract text is available yet for this article.
June 13, 2018: Annals of Allergy, Asthma & Immunology
Debra A Fleischman, Konstantinos Arfanakis, Sue Leurgans, Sheila M Keating, Melissa Lamar, David A Bennett, Oluwatoyin M Adeyemi, Lisa L Barnes
Objective: HIV infection sets off an immediate immune response and inflammatory cascade that can lead to neuronal injury and cognitive impairment, but the relationship between immune markers, regional brain volumes, and cognition remains understudied in HIV-infected adults. Methods: Cross-sectional associations were examined between serum immune markers of activation (neopterin) and inflammation (interleukin [IL]-1β, IL-6, tumor necrosis factor alpha, and C-reactive protein) with regional brain volumes (cortical, subcortical, total gray matter, hippocampus, and subfields) and cognition in 66 HIV-infected, virally suppressed, adults who underwent 3...
July 2018: Neurology® Neuroimmunology & Neuroinflammation
Lin Zang, Feiyue Mao, Jianping Guo, Wei Gong, Wei Wang, Zengxin Pan
Particulate matter with diameter less than 1 μm (PM1 ) has been found to be closely associated with air quality, climate changes, and even adverse human health. However, a large gap in our knowledge concerning the large-scale distribution and variability of PM1 remains, which is expected to be bridged with advanced remote-sensing techniques. In this study, a hybrid model called principal component analysis-general regression neural network (PCA-GRNN) is developed to estimate hourly PM1 concentrations from Himawari-8 aerosol optical depth in combination with coincident ground-based PM1 measurements in China...
June 11, 2018: Environmental Pollution
Bryan D James, Robert S Wilson, Raj C Shah, Lei Yu, Zoe Arvanitakis, David A Bennett, Patricia A Boyle
BACKGROUND: Lowering the likelihood of hospitalization in older adults is a major public health goal for modern health care systems. Emerging data suggest that financial literacy is an important determinant of health outcomes in old age, but the relationship with hospitalization has not been explored. OBJECTIVE: To test the hypothesis that better financial literacy is related to lower risk of hospitalization in older persons. DESIGN: Prospective cohort study...
July 2018: Medical Care
Julian C Hong, Yunfeng Cui, Bhavik N Patel, Christel N Rushing, Austin M Faught, Jared S Eng, Kyle Higgins, Fang-Fang Yin, Shiva Das, Brian G Czito, Christopher G Willett, Manisha Palta
PURPOSE: Imaging parameters from 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) before and after chemoradiation therapy (CRT) for anal canal cancer correlate with clinical outcomes. This prospective, hypothesis-generating pilot study investigates the relationship between interim PET imaging during CRT for anal canal cancer and clinical outcome. METHODS AND MATERIALS: From June 2012 to August 2015, 30 patients with anal canal cancer were enrolled in a prospective clinical study of PET prior to and during CRT after ∼30 Gy...
May 4, 2018: International Journal of Radiation Oncology, Biology, Physics
Stephen C Rush, Christopher Foresto, Christopher W Hewitt, Marc G Grossman, Christopher D Petersen, Isabelle Gallo, Brian P Staak, Jessica T Rush
Operators perform physically demanding jobs associated with a variety of overuse and acute musculoskeletal injuries. The current management of musculoskeletal complaints in the Air Force includes plane radiographs and 6 weeks of physical therapy (PT) before consideration of orthopedic consultation and magnetic resonance imaging (MRI); however, MRI shows a clear advantage compared with plane radiographs. We conducted a performance improvement project and conclude that (1) MRI allowed for definitive diagnosis as well as definitive triage for care in a timely manner, (2) guidelines for ordering lumbosacral MRIs should be followed and not ordered for pain that is not progressive and severe or not associated with a neurological finding, and (3) because of the risk of X-ray exposure in patients in their 20 and 30s, X-rays should be avoided in this setting unless definitely indicated...
2018: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
William Makis, Mark Palayew, Christopher Rush, Stephan Probst
A 60-year-old female with no significant medical history presented with hematuria. A computed tomography (CT) scan revealed extensive lymphadenopathy with hypodensities in the liver and spleen, and she was referred for an 18 F-fluorodeoxyglucose (18 F-FDG) positron emission tomography/CT (PET/CT) study to assess for malignancy of unknown primary. PET/CT revealed extensive 18 F-FDG avid lymphadenopathy as well as innumerable intensely 18 F-FDG avid lung, liver and splenic nodules, highly concerning for malignancy...
June 7, 2018: Molecular Imaging and Radionuclide Therapy
Matthias H Hoffmann, Sebastian Gebauer, Torsten von Rozycki
PREMISE OF THE STUDY: Understanding the origin of ecosystems and their changes through time is important. Two mutually contrasting types of grasslands existed in the Arctic: dry- and cold-adapted grasslands of the Pleistocene dominated by Poaceae species, and presently dominating graminoid grasslands composed of sedges and rushes. We studied the taxon recruitment of the Arctic flora for Carex, the most species-rich and widespread genus of the Arctic. In this study we explore the possible geographical and altitudinal origins of the species, their ecological provenance in terms of soil moisture and light requirements, and salt tolerance...
September 2017: American Journal of Botany
Kenneth A Perkins, Taylor Herb, Joshua L Karelitz
INTRODUCTION: Behavioral discrimination of nicotine has only recently been assessed in humans, administered mostly by nasal spray before the newly available Spectrum research cigarettes differing in nicotine content. Here we wanted to explore applicability of these procedures to assess discrimination of nicotine administered by e-cigarettes. METHODS: In this feasibility study, 16 adult smokers were tested on ability to discriminate e-cigarettes with nicotine concentrations of 36, 24, and 12 mg/ml, one per session (in that order), from a placebo (0 mg/ml), each identified only by letter code...
May 29, 2018: Addictive Behaviors
Rebecca C Ahrens-Nicklas, Rebecca D Ganetzky, Peggy W Rush, Robert L Conway, Can Ficicioglu
BACKGROUND: Glutamate formiminotransferase deficiency (FTCD deficiency) or formiminoglutamic aciduria is the second most common of the known inherited disorders of folate metabolism. Initial case reports suggested that patients may have severe intellectual disability and megaloblastic anemia. However, these cases were obtained from screening cohorts of patients with developmental delay. Subsequently, patients with milder clinical phenotypes have been reported. The full phenotypic spectrum of this disorder remains unknown...
June 4, 2018: Journal of Inherited Metabolic Disease
M J Gupta, S Shah, S Peterson, S Baim
In spite of being a public health problem of pandemic proportions, osteoporosis continues to be underdiagnosed and undertreated especially in older adults with fragility fractures. Confirmation of this hypothesis resulted in the development of a novel Fracture Liaison Service (Rush FLS). Results of the first 12 months of operation revealed that patients with confirmed fragility fracture do not have a timely diagnosis at fracture occurrence or treatment of their disease. The Rush FLS is an effective fracture liaison model...
June 4, 2018: Osteoporosis International
Miguel Simancas-Pallares, Mike T John, Swati Prodduturu, William A Rush, Christopher J Enstad, Patricia Lenton
PURPOSE: To develop a Spanish version of the Orofacial Esthetic Scale (OES-Sp) and to determine its psychometric properties in dental patients. METHODS: We performed a validation study for OES development and validation into Spanish. In the development phase, eight individuals participated in the translation process (cross-cultural adaptation) following the PROMIS methodology. In the validation phase, 331 dental patients (age mean±sd: 42.9±12.3years, 59 % female) from the HealthPartners dental clinics in Minnesota, USA responded to a survey of Spanish speaking patients (n=540, response rate: 61 %)...
June 1, 2018: Journal of Prosthodontic Research
Karen Urbanoski, Chris Kenaszchuk, Dakota Inglis, Nooshin Khobzi Rotondi, Brian Rush
Understanding the nature of variations in the quality of substance use treatment is critical to ensuring equity in service delivery and maximizing treatment effectiveness. We used adapted versions of the US Healthcare Effectiveness Data and Information Set (HEDIS) treatment initiation and engagement measures to assess care quality in specialized outpatient services for substance use in Ontario, Canada. Using administrative data, we calculated rates of outpatient treatment initiation and engagement (N = 120,394 episodes) and investigated variation by client characteristics and treatment mandates...
July 2018: Journal of Substance Abuse Treatment
David A Bennett, Aron S Buchman, Patricia A Boyle, Lisa L Barnes, Robert S Wilson, Julie A Schneider
BACKGROUND: The Religious Orders Study and Rush Memory and Aging Project are both ongoing longitudinal clinical-pathologic cohort studies of aging and Alzheimer's disease (AD). OBJECTIVES: To summarize progress over the past five years and its implications for understanding neurodegenerative diseases. METHODS: Participants in both studies are older adults who enroll without dementia and agree to detailed longitudinal clinical evaluations and organ donation...
May 26, 2018: Journal of Alzheimer's Disease: JAD
Michael A Towler, Elaine W Rush, Melissa K Richardson, Calvin L Williams
Chronic venous leg ulcers are responsible for significant morbidity and health care costs worldwide. This pilot study evaluated the effectiveness 2 biologically active grafts, TheraSkin and Apligraf, in conjunction with compression therapy. The study, not industry-sponsored, was designed and conducted as a prospective, head-to-head, single-site, randomized clinical trial to assess differences in healing rates, adverse outcomes, and treatment costs. The healing rates were different but not statistically significant, there were no adverse outcomes, and TheraSkin averaged $2495...
July 2018: Clinics in Podiatric Medicine and Surgery
Angèle P M Kerckhoffs, Erwin G T M Hartong, Koen P Grootens
BACKGROUND: Lithium is the treatment of choice for patients suffering from bipolar disorder (BD) but prolonged use induces renal dysfunction in at least 20% of patient. Intensive monitoring of kidney functioning helps to reveal early decline in renal failure. This study investigates the views and experiences of BD patients who have developed end-stage renal disease and were receiving renal replacement therapy. RESULTS: The patients overall reported not to have been offered alternative treatment options at the start of lithium therapy or when renal functions deteriorated...
June 2, 2018: International Journal of Bipolar Disorders
Jonathan Owen
No abstract text is available yet for this article.
May 30, 2018: BMJ: British Medical Journal
Heidi Ledford
No abstract text is available yet for this article.
May 2018: Nature
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