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Wenxin Yu, Tianyou Wang, Jiafang Zhu, Yajing Qiu, Hui Chen, Yunbo Jin, Xi Yang, Xiaojie Hu, Lei Chang, Yijie Chen, Gang Ma, Xiaoxi Lin
EMLA cream was developed to reduce pain during pulsed-dye laser (PDL) treatment; however, no standard assessment for the therapeutic outcomes of PDL with EMLA creams thus far available. This comparative, prospective clinical trial evaluates laser efficacy and pain reduction during PDL treatment with EMLA cream for local topical anesthesia. Nineteen patients with untreated port-wine stain (PWS) were treated using PDL and examined in this study. Treatment specifications included Vbeam® PDL (Candela Corp.), 595-nm wavelength, 9 J/cm2 radiant exposure, 0...
December 15, 2017: Lasers in Medical Science
Wenxin Yu, Hanru Ying, Yijie Chen, Yajing Qiu, Hui Chen, Yunbo Jin, Xi Yang, Tianyou Wang, Gang Ma, Xiaoxi Lin
OBJECTIVE: Pulsed dye laser (PDL) with 7 and 10 mm spot sizes is widely used on a regular basis for the treatment of port-wine stain (PWS). BACKGROUND DATA: No studies have reported on the differences in efficacy outcomes resulting from the use of different laser spot sizes in the treatment of PWS by PDL. Thus, an in vivo investigation into the differences in safety and efficacy of treatment between two spot sizes (7 vs. 10 mm) of PWS by PDL was conducted. MATERIALS AND METHODS: A total of 35 PWS patients underwent three treatment sessions by using a 595 nm wavelength PDL (Vbeam(®), Candela Corp) with two laser settings: (1) 7 mm spot size, radiant exposure of 12 J/cm(2) and (2) 10 mm spot size, radiant exposure of 10 J/cm(2)...
September 2017: Photomedicine and Laser Surgery
Bonnie C Swan, Susan J Robertson, Alana Tuxen, Ellen Ma, Leona Yip, Lena Ly, Linda Bingham, Andrew Davidson, Philip Bekhor
Capillary malformations (CM) cause significant psychosocial complications. Pulsed dye laser (PDL) treatment at 6-12-weekly intervals under general anaesthesia (GA) commencing in infants at 6 months of age remains the standard of care in order to achieve maximal improvement prior to school age. The safety of repeated GA in children is controversial. Shortening the time between treatments increases the number that can be delivered prior to 6 months of age, thus reducing the number of subsequent treatments needed under GA...
August 2017: Australasian Journal of Dermatology
Thomas D Griffin, James P Foshee, Robert Finney, Nazanin Saedi
BACKGROUND AND OBJECTIVE: A port wine stain (PWS) is a type of capillary vascular malformation composed of malformed, dilated blood vessels within the papillary and reticular dermis. Currently, pulsed dye laser (PDL) is considered the therapeutic gold standard, although greater than 90% of lesions may be refractory to treatment. Studies have shown that a delay in treatment results in a higher proportion of patients who develop hypertrophy and nodularity within lesions that become more resistant to therapy...
February 2016: Lasers in Surgery and Medicine
W Yu, G Ma, Y Qiu, H Chen, Y Jin, X Yang, L Chang, T Wang, X Hu, W Li, X Lin
BACKGROUND: Vbeam(®) and Cynergy(®) are 595-nm pulsed-dye laser (PDL) equipment options, both extensively used in the clinical treatment of port-wine stains (PWS). However, there has been no study conducted of the differences in PWS therapeutic outcomes across both devices. OBJECTIVES: To compare the efficacy and safety of Vbeam and Cynergy equipment in the treatment of PWS. METHODS: Twenty-two patients with PWS were included in this study and were treated with both Vbeam and Cynergy...
March 2015: British Journal of Dermatology
S Leu, J Havey, L E White, N Martin, S S Yoo, A W Rademaker, M Alam
BACKGROUND: Dermatological procedures can result in disfiguring bruises that resolve slowly. OBJECTIVES: To assess the comparative utility of topical formulations in hastening the resolution of skin bruising. METHODS: Healthy volunteers, age range 21-65 years, were enrolled for this double (patient and rater) blinded randomized controlled trial. For each subject, four standard bruises of 7 mm diameter each were created on the bilateral upper inner arms, 5 cm apart, two per arm, using a 595-nm pulsed-dye laser (Vbeam; Candela Corp...
September 2010: British Journal of Dermatology
Vishal Madan, Janice Ferguson
Thick linear telangiectasia on the ala nasi and nasolabial crease can be resistant to treatment with the potassium-titanyl-phosphate (KTP) laser and the traditional round spot on a pulsed dye laser (PDL). We evaluated the efficacy of a 3 mm x 10 mm elliptical spot using the ultra-long pulse width on a Candela Vbeam(R) PDL for treatment of PDL- and KTP laser-resistant nasal telangiectasia. Nasal telangiectasia resistant to PDL (12 patients) and KTP laser (12 patients) in 18 patients were treated with a 3 mm x 10 mm elliptical spot on the ultra-long pulse pulsed dye laser (ULPDL) utilising long pulse width [595 nm, 40 ms, double pulse, 30:20 dynamic cooling device (DCD)]...
January 2010: Lasers in Medical Science
S-T Cheung, S W Lanigan
Granuloma faciale (GF) is a rare cutaneous condition of unknown origin with characteristic clinicopathological features. It predominantly affects the face and in some causes an unacceptable cosmetic appearance. Numerous medical and surgical treatments have been used with varying degrees of success. Several single-patient case reports have demonstrated the successful use of the pulsed dye laser (PDL) in treating GF. This study assesses the results of four patients with facial GF from one dermatological laser centre that were treated with the Candela Vbeam PDL at 595 nm...
July 2005: Clinical and Experimental Dermatology
Linda C Wang, Aleksandar L Krunic, Maria M Medenica, Keyoumars Soltani, Shail Busbey
Hemorrhagic lymphatic malformation (formerly called hemolymphangioma) of the tongue is an uncommon malformation that may pose both functional and cosmetic problems for the patient. The challenge has been to find a conservative treatment with low morbidity and better results than those achieved with surgical excision, which has been the mainstay of therapy. We report a case of successful treatment of a hemorrhagic lymphatic malformation of the tongue with a variable-pulse 595-nm pulsed-dye laser (Vbeam; Candela Corp, Wayland, Mass)...
June 2005: Journal of the American Academy of Dermatology
Thomas E Rohrer, Vandana Chatrath, Vivek Iyengar
BACKGROUND: It has been suggested that multiple stacked pulses of lower fluence may have a similar effect on targets as a single pulse of higher fluence. When treating vascular lesions, increasing the fluence beyond a certain point will increase the risk of purpura given a constant pulse duration. Stacking pulses of lower fluence may have the advantage of heating vessels to a critical temperature without creating purpura. OBJECTIVE: To determine whether stacking low-fluence pulses of a variable-pulse pulsed-dye laser would improve clinical results without significantly increasing side and adverse effects...
February 2004: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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