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contralateral mastectomy

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https://www.readbyqxmd.com/read/29302489/enhancing-breast-projection-in-autologous-reconstruction-using-the-st-andrew-s-coning-technique-and-3d-volumetric-analysis
#1
Michael P Chae, Warren Matthew Rozen, Nakul Gamanlal Patel, David J Hunter-Smith, Venkat Ramakrishnan
Background: An increasing number of women undergo mastectomy for breast cancer and post-mastectomy autologous breast reconstruction has been shown to significantly improve the psychosexual wellbeing of the patients. A goal of treatment is to achieve symmetry and projection to match the native breast, and/or the contralateral breast in the case of a unilateral reconstruction. Autologous reconstruction, particularly with the deep inferior epigastric artery perforator (DIEP) flap, is particularly advantageous as it can be manipulated to mimic the shape and turgor of the native breast...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29302487/central-round-block-repair-of-large-breast-resection-defects-oncologic-and-aesthetic-outcomes
#2
Russell J Bramhall, Jason Lee, Mae Concepcion, David Westbroek, Sarah Huf, Kabir Mohammed, Paul Thiruchelvam, Gerald P Gui
Background: The central round block repair is a volume displacement technique to reconstruct large wide local excision (WLE) defects in breasts with moderate ptosis or hypertrophy. There are limited published data on the outcomes of this technique. Methods: Data were collected prospectively for 57 consecutive patients and follow up information obtained from patient records. The volume of breast resection was estimated geometrically from mammography. Aesthetic outcomes were assessed from clinical measurements and panel review of patient photographs...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29288115/mastectomy-for-risk-reduction-or-symmetry-in-women-without-high-risk-gene-mutation-a-review
#3
REVIEW
R Kenny, M Reed, A Subramanian
BACKGROUND: Prophylactic or 'risk-reducing' mastectomy refers to the procedure of completely removing a healthy breast in order to reduce the risk of developing breast cancer. This may be bilateral or may be performed to the contralateral breast as part of the treatment of a proven breast cancer. The rate of this procedure being performed has been shown to be increasing over the last two decades. Recent guidance for Breast clinicians has been issued over the last 12 months by both The Association of Breast Surgery of Great Britain and Ireland (ABSGBI) and the American Society of Breast Surgeons (ASBrS)...
December 26, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29275104/one-step-prepectoral-breast-reconstruction-with-dermal-matrix-covered-implant-compared-to-submuscular-implantation-functional-and-cost-evaluation
#4
Leonardo Cattelani, Susanna Polotto, Maria Francesca Arcuri, Giuseppe Pedrazzi, Chiara Linguadoca, Elena Bonati
BACKGROUND: The breast reconstructive subpectoral technique commonly leads to functional consequences. Recently, a new conservative prepectoral breast reconstruction (PPBR) technique was proposed and its surgical safety and aesthetic effectiveness proved. The aim of this prospective nonrandomized study was to compare the functional and economical outcomes of the PPBR procedure versus the subpectoral one. PATIENTS AND METHODS: From February 2015 to September 2016, 86 patients underwent mastectomy with immediate implant-based reconstruction...
December 2, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29251681/rising-rates-of-contralateral-prophylactic-mastectomy-as-a-treatment-for-early-stage-breast-cancer
#5
Bonnie Jerome-DʼEmilia, Debashis Kushary, Patricia D Suplee
BACKGROUND: The rate of contralateral prophylactic mastectomy (CPM) in women with unilateral mastectomy is increasing with no plateau. OBJECTIVES: The aim of this study was to improve the understanding of patient- and tumor-related factors that influenced the choice of mastectomy with CPM as treatment for early-stage breast cancer at an academic medical center in New Jersey. METHODS: This was a retrospective analysis of 10 years of breast cancer data including 1556 women aged 40 to 80 years treated for breast cancer at an academic medical center...
December 14, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/29239797/autologous-breast-reconstruction-using-the-immediately-lipofilled-extended-latissimus-dorsi-flap
#6
N Johns, N Fairbairn, M Trail, A Ewing, L Yong, C Raine, J M Dixon
BACKGROUND: The latissimus dorsi flap is a popular choice for autologous breast reconstruction. To dramatically improve volume, we report our experience of using the immediately lipofilled extended latissimus dorsi (ELD) flap and show it as a valid option for autologous breast reconstruction. METHODS: Patients undergoing the procedure between December 2013 and June 2016 were included. Demographic, clinical and operative factors were analysed, together with in-hospital morbidity and duration of postoperative hospital stay...
November 24, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29233470/isolated-contralateral-axillary-lymph-node-involvement-in-breast-cancer-represents-a-locally-advanced-disease-not-distant-metastases
#7
Rati Chkheidze, Mary Ann G Sanders, Barbara Haley, A Marilyn Leitch, Sunati Sahoo
BACKGROUND: Breast cancer metastases to an ipsilateral supraclavicular lymph node is assigned a N3 status in the TNM system and thus classified as stage III disease in the American Joint Commission on Cancer staging manual. Breast cancer metastatic to contralateral axillary lymph node (CAM) without metastases to any other distant organ is currently assigned M1 status (stage IV) instead of N3 (stage III). PATIENTS AND METHODS: We retrospectively reviewed the medical records of breast cancer patients diagnosed with CAM for their clinical presentation, pathologic diagnoses, treatment, and follow-up data...
November 10, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29176636/genetic-and-clinical-characteristics-in-japanese-hereditary-breast-and-ovarian-cancer-first-report-after-establishment-of-hboc-registration-system-in-japan
#8
Masami Arai, Shiro Yokoyama, Chie Watanabe, Reiko Yoshida, Mizuho Kita, Megumi Okawa, Akihiro Sakurai, Masayuki Sekine, Junko Yotsumoto, Hiroyuki Nomura, Yoshinori Akama, Mayuko Inuzuka, Tadashi Nomizu, Takayuki Enomoto, Seigo Nakamura
The hereditary breast and ovarian cancer (HBOC) registration system of Japan was established by the Japanese HBOC Consortium. The first trial was registered in 2015 in four institutions to which some registration committee members belonged. We analyzed the information of 830 Japanese pedigrees, who underwent BRCA1/2 genetic testing, including mutation carriers with BRCA1 (N = 127) and BRCA2 (N = 115), and their families. The mutation-positive rate was 19.7%. Variants of uncertain significance were found in 6...
November 8, 2017: Journal of Human Genetics
https://www.readbyqxmd.com/read/29166308/an-evaluation-of-the-choice-for-contralateral-prophylactic-mastectomy-and-patient-concerns-about-recurrence-in-a-reconstructed-cohort
#9
Ian C Sando, Jessica I Billig, Shoshana W Ambani, Casey T Kraft, Kelley M Kidwell, Lin Zhong, Kevin C Chung, Adeyiza O Momoh
BACKGROUND: Rising contralateral prophylactic mastectomy rates are a subject of national concern. This study assessed (1) factors critical to patients when deciding on contralateral prophylactic mastectomy and (2) patients' quality of life related to concerns about recurrence after unilateral or bilateral breast reconstruction. METHODS: Patients with stage 0 to III breast cancer who underwent unilateral mastectomy or contralateral prophylactic mastectomy and breast reconstruction at a single institution between 2000 and 2012 were identified...
November 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29164974/clinical-and-molecular-characterization-of-brca-associated-breast-cancer-results-from-the-dbcg
#10
I M H Soenderstrup, A V Laenkholm, M B Jensen, J O Eriksen, A M Gerdes, T V O Hansen, T A Kruse, M J Larsen, I S Pedersen, M Rossing, M Thomassen, B Ejlertsen
BACKGROUND: In breast cancer (BC) patients a cancer predisposing BRCA1/2 mutation is associated with adverse tumor characteristics, risk assessment and treatment allocation. We aimed to estimate overall- (OS) and disease-free survival (DFS) according to tumor characteristics and treatment among women who within two years of definitive surgery for primary BC were shown to carry a mutation in BRCA1/2 . MATERIAL AND METHODS: From the clinical database of the Danish Breast Cancer Group we included 141 BRCA1 and 96 BRCA2 BC patients...
January 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29147896/genetic-diagnosis-before-surgery-has-an-impact-on-surgical-decision-in-brca-mutation-carriers-with-breast-cancer
#11
Sungmin Park, Jeong Eon Lee, Jai Min Ryu, Issac Kim, Soo Youn Bae, Se Kyung Lee, Jonghan Yu, Seok Won Kim, Seok Jin Nam
BACKGROUND: The first aim of our study was to evaluate surgical decision-making by BRCA mutation carriers with breast cancer based on the timing of knowledge of their BRCA mutation status. The second aim was to evaluate breast cancer outcome following surgical treatment. METHODS: This was a retrospective study of 164 patients diagnosed with invasive breast cancer, tested for BRCA mutation, and treated with primary surgery between 2004 and 2015 at Samsung Medical Center in Seoul, Korea...
November 16, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29127760/preoperative-breast-mri-examination-for-all-patients-with-histologically-proven-breast-cancer-a-concept-for-a-prospective-multicenter-trial
#12
Christina Kaiser, Christina Kehrer, Mignon-Denise Keyver-Paik, Thomas Hecking, Tiyasha Hosne Ayub, Claudia Leutner, Hans Schild, Walther Kuhn
Background A published retrospective data of our study group demonstrated that premenopausal women, patients with lobular invasive breast cancer or patients with high breast density [American College of Radiology (ACR) classification 3+4] significantly benefit from magnetic resonance imaging (MRI) leading to additional detection of malignant foci of 20.2% in the index and 2.5% in the contralateral breast, which would otherwise not be detected by routine imaging. Critics of preoperative MRI focus on higher false-positive rates leading to unnecessary surgical procedures and mastectomies...
November 11, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/29127715/relationship-between-preoperative-breast-mri-and-surgical-treatment-of-non-metastatic-breast-cancer
#13
Tracy Onega, Julie E Weiss, Martha E Goodrich, Weiwei Zhu, Wendy B DeMartini, Karla Kerlikowske, Elissa Ozanne, Anna N A Tosteson, Louise M Henderson, Diana S M Buist, Karen J Wernli, Sally D Herschorn, Elise Hotaling, Cristina O'Donoghue, Rebecca Hubbard
BACKGROUND AND OBJECTIVES: More extensive surgical treatments for early stage breast cancer are increasing. The patterns of preoperative MRI overall and by stage for this trend has not been well established. METHODS: Using Breast Cancer Surveillance Consortium registry data from 2010 through 2014, we identified women with an incident non-metastatic breast cancer and determined use of preoperative MRI and initial surgical treatment (mastectomy, with or without contralateral prophylactic mastectomy (CPM), reconstruction, and breast conserving surgery ± radiation)...
December 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29124356/low-lifetime-risk-of-contralateral-breast-cancer-in-a-middle-income-asian-country-evidence-to-guide-post-treatment-surveillance
#14
M H See, N Bhoo-Pathy, S Jamaris, A Kiran, D G Evans, C H Yip, N A Taib
BACKGROUND: The rate of contralateral risk-reducing mastectomy (CRRM) is increasing in the West with controversial evidence of improved survival in early breast cancer patients. Although uptake of CRRM in Asia appears low, the trends may rise, and there is currently an urgent need to provide evidence for informed decision-making in clinical practice. This study aims to determine the risk of contralateral breast cancer (CBC) and its associated factors in an Asian setting. METHOD: A total of 2937 newly diagnosed patients with stage I and stage II breast cancer in University Malaya Medical Centre between Jan 1993 to Dec 2012 were included in the study...
November 9, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29103479/is-breast-magnetic-resonance-imaging-mri-useful-for-diagnosis-of-additional-sites-of-disease-in-patients-recently-diagnosed-with-pure-ductal-carcinoma-in-situ-dcis
#15
A P Benveniste, T Ortiz-Perez, L O Ebuoma, K A Sepulveda, F J Severs, A Roark, T Wang, E L Sedgwick
PURPOSE: To determine if breast MRI is useful for detecting additional or invasive sites of disease in patients initially diagnosed with pure DCIS. MATERIALS AND METHODS: A retrospective review of women diagnosed with pure DCIS who underwent a breast MRI for evaluation of extent of disease was performed at a single institution from January 2013 to April 2015. Data analysis included imaging (mammography, ultrasound and MRI) and pathology characteristics (histology and biomarker status) of the primary DCIS as well as descriptors for the additional sites of disease incidentally found by breast MRI...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29080654/risk-reducing-mastectomy-and-breast-reconstruction-indications-and-evidence-for-current-management-strategies
#16
REVIEW
Bradley S Eisemann, Aldona J Spiegel
Breast cancer affects nearly every woman either personally or through a family member or friend. Awareness of associated familial and genetic risks has been steadily increasing over the last decade. Bilateral risk-reduction mastectomy seeks to decrease the incidence and mortality of breast cancer in women without abnormality but with elevated risk of developing cancer. Contralateral risk-reduction mastectomy aims to decrease the incidence of contralateral breast cancer in women diagnosed with unilateral breast cancer...
January 2018: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/29075821/mastopexy-on-reconstructed-breast-following-massive-weight-loss-an-innovative-technique-using-dermo-capsular-flaps
#17
A Cogliandro, M Barone, G Cassotta, R Salzillo, P Persichetti
BACKGROUND: We have developed a dermo-capsular flap mastopexy technique for patients who have experienced massive weight loss after breast reconstruction. The aim of this technique is to lift the inframammary fold, adequately cover the implant, and remove excess skin, elevating the breast and obtaining symmetry with the contralateral breast. METHODS: Between January 2014 and February 2017, we performed this technique on 20 women who were candidates for second-stage breast reconstruction following nipple-sparing mastectomy...
October 26, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29064917/current-trends-in-postmastectomy-breast-reconstruction
#18
REVIEW
Hina Panchal, Evan Matros
Postmastectomy immediate breast reconstruction in the U.S. continues to experience an upward trend owing to heightened awareness, innovations in reconstructive technique, growing evidence of improved patient-reported outcomes, and shifts in mastectomy patterns. Women with unilateral breast cancer are increasingly electing to undergo contralateral prophylactic mastectomy, instead of unilateral mastectomy or opting for breast conservation. The ascent in prophylactic surgeries correlates temporally to a shift toward prosthetic methods of reconstruction as the most common technique...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29064771/contralateral-prophylactic-mastectomy-a-qualitative-approach-to-exploring-the-decision-making-process
#19
Judith R Greener, Sarah Bauerle Bass, Stephen J Lepore
The proportion of women with unilateral breast cancer and no familial or genetic risk factors who elect contralateral prophylactic mastectomy (CPM) has grown dramatically, even in the absence of clear data demonstrating improved outcomes. To further extend the literature that addresses treatment decision-making, qualitative interviews were conducted with eleven women who considered CPM. A social ecological model of breast cancer treatment decision-making provided the conceptual framework, and grounded theory was used to identify the cognitive, psychosocial, and emotional influences motivating treatment choice...
October 24, 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/29058926/-breast-angiosarcoma-induced-by-radiotherapy-surgical-treatment-options-and-review-of-literature
#20
O Kubala, J Prokop, L Petráš, P Ihnát, P Jelínek, P Ostruszka
INTRODUCTION: Radiation-induced angiosarcoma is a rare but very aggressive tumour. The highest risk of sarcoma development is in patients after breast-conserving surgery.Case 1: The 66 years old patient underwent radical mastectomy with axillary dissection because of ductal carcinoma with consequent radiotherapy, chemotherapy and hormonal therapy. After 6 years, high-grade angiosarcoma was diagnosed and resected with negative resection margins. Within subsequent 24 months, additional three radical re-excisions were performed because of repeated sarcoma recurrence...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
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