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Arun D Singh, William J Dupps, Charles V Biscotti, John H Suh, Kira L Lathrop, John P Nairn, Helen Shih
PURPOSE: To report the outcome after limbal stem cell preservation during proton beam irradiation for diffuse iris melanoma. METHODS: This is a single-case report of diffuse iris melanoma that was managed with proton beam radiation (53 Gy), wherein preemptively harvested superior and inferior limbal stem cells before radiation were replaced after irradiation. Regeneration of the palisades of Vogt and the limbal stem cells was documented by an optical coherence tomography-based imaging protocol...
October 14, 2016: Cornea
A A Baker, A I Figueroa, D Pingstone, V K Lazarov, G van der Laan, T Hesjedal
We present a study of the interaction mechanisms in magnetic trilayer structures with an MgO barrier grown by molecular beam epitaxy. The interlayer exchange coupling, Aex, is determined using SQUID magnetometry and ferromagnetic resonance (FMR), displaying an unexpected oscillatory behaviour as the thickness, tMgO, is increased from 1 to 4 nm. Transmission electron microscopy confirms the continuity and quality of the tunnelling barrier, eliminating the prospect of exchange arising from direct contact between the two ferromagnetic layers...
October 18, 2016: Scientific Reports
David R Diercks, Brian P Gorman, Johannes J L Mulders
Six precursors were evaluated for use as in situ electron beam-induced deposition capping layers in the preparation of atom probe tomography specimens with a focus on near-surface features where some of the deposition is retained at the specimen apex. Specimens were prepared by deposition of each precursor onto silicon posts and shaped into sub-70-nm radii needles using a focused ion beam. The utility of the depositions was assessed using several criteria including composition and uniformity, evaporation behavior and evaporation fields, and depth of Ga+ ion penetration...
October 17, 2016: Microscopy and Microanalysis
Vikneswary Batumalai, Penny Phan, Callie Choong, Lois Holloway, Geoff P Delaney
INTRODUCTION: To compare the differences in setup errors measured with electronic portal image (EPI) and cone-beam computed tomography (CBCT) in patients undergoing tangential breast radiotherapy (RT). Relationship between setup errors, body mass index (BMI) and breast size was assessed. METHODS: Twenty-five patients undergoing postoperative RT to the breast were consented for this study. Weekly CBCT scans were acquired and retrospectively registered to the planning CT in three dimensions, first using bony anatomy for bony registration (CBCT-B) and again using breast tissue outline for soft tissue registration (CBCT-S)...
May 31, 2016: Journal of Medical Radiation Sciences
H Móciková, J Marková, Ľ Gahérová, Z Král, A Sýkorová, D Belada, V Procházka, L Martinková, T Papajík, T Kozák
High-dose chemotherapy with autologous stem cell transplantation remains the current standard of treatment for young patients with Hodgkin lymphoma in first relapse or in those who are refractory to first-line treatment. The most important prognostic factors in relapses are clinical stage IV, poor performance status, bulky mass, and less than partial remission after salvage chemotherapy. Standard salvage chemotherapy in relapse before autologous transplantation has not been defined; however, DHAP and ICE are most frequently used in this setting...
2016: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
F Barchetti, A Stagnitti, V Megna, N Al Ansari, A Marini, D Musio, M L Monti, G Barchetti, V Tombolini, C Catalano, V Panebianco
OBJECTIVE: The aim of this study was to evaluate the accuracy of unenhanced whole-body MRI, including whole-body Diffusion Weighted Imaging (DWI), used as a diagnostic modality to detect  pathologic lymph nodes and skeletal metastases in patients with prostate cancer (PCa) undergoing restaging after primary treatment. PATIENTS AND METHODS: 152 male patients with biochemical recurrence after radical prostatectomy (RP) or external beam radiation therapy (EBRT) underwent MRI at a 1...
September 2016: European Review for Medical and Pharmacological Sciences
Joanna M Laba, Timothy K Nguyen, R Gabriel Boldt, Alexander V Louie
Chylothorax is a rare complication of advanced lymphoma. We present the case of an 80-year-old man diagnosed with B cell lymphoma presenting with a right chylothorax secondary to a large retroperitoneal mass. His disease was not responsive to initial treatment with chemotherapy. Fractionated radiotherapy to a dose of 2,000 cGy in five fractions was delivered to the retroperitoneal mass, and the chylothorax improved significantly within days of initiation of treatment.
August 31, 2016: Curēus
Aghiad Ghazal, Josiane P Lafleur, Kell Mortensen, Jörg P Kutter, Lise Arleth, Grethe V Jensen
The increasingly narrow and brilliant beams at X-ray facilities reduce the requirements for both sample volume and data acquisition time. This creates new possibilities for the types and number of sample conditions that can be examined but simultaneously increases the demands in terms of sample preparation. Microfluidic-based sample preparation techniques have emerged as elegant alternatives that can be integrated directly into the experimental X-ray setup remedying several shortcomings of more traditional methods...
October 12, 2016: Lab on a Chip
Anouar Rahmouni, Yahya Bougdid, Sara Moujdi, Dmitry V Nesterenko, Zouheir Sekkat
Holographic storage is one of the most important applications in the field of optics, especially for recording and retrieving data, and information storage by interference patterns in photosensitive materials are no exception in this regard. In this work, we give evidence that holograms recorded by interference of two-coherent laser beams in azo dye doped polymer films can be controlled by a third incoherent assisting laser beam. We show that light diffraction can be increased or decreased by an assisting beam depending on the respective orientation of the polarizations of the recording and the assisting beams...
October 11, 2016: Journal of Physical Chemistry. B
Thai V Hoang, Caroline Kizilyaprak, Danièle Spehner, Bruno M Humbel, Patrick Schultz
Focused Ion Beam milling combined with Scanning Electron Microscopy is a powerful tool to determine the 3-D organization of whole cells and tissue at an isotropic resolution of 3-5nm. This opens the possibility to quantify several cellular parameters and to provide detailed phenotypic information in normal or disease states. Here we describe Biocomputing methods to extract in an automated way characteristic features of mouse rod photoreceptor nuclei such as the shape and the volume of the nucleus; the proportion of heterochromatin; the number, density and distribution of nuclear pore complexes (NPC)...
October 8, 2016: Journal of Structural Biology
Karthik Selvaraj, Vidhya Sampath, V Sujatha, S Mahalaxmi
AIMS: The aim of this in vitro study was to comparatively evaluate the microshear bond strength (MSBS) of etch-and-rinse and self-etch (ER and SE) bonding systems to dentin pretreated with silver diamine fluoride/potassium iodide (SDF/KI) and nanoleakage at the resin-dentin interface using transmission electron microscope (TEM). SUBJECTS AND METHODS: Seventy-two dentin slabs of 3 mm thickness were prepared from extracted human permanent third molars and divided into four groups (n = 18) based on the dentin surface treatment as follows: (1) ER adhesive bonding without dentin pretreatment; (2) SDF/KI pretreatment of dentin followed by ER adhesive bonding; (3) SE adhesive bonding without dentin pretreatment; and (4) SDF/KI pretreatment of dentin followed by SE adhesive bonding...
July 2016: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
Jeenal V Gupta, P G Makhija, K C Gupta
AIM: To find the correlation between nasal airway volume and the craniofacial morphology using cone beam computed tomography (CBCT). MATERIALS AND METHODS: This study consisted of preorthodontic anonymized CBCT scans of 34 healthy adults in the age span of 18-28 years. The volume was calculated using Dolphin 3D R software 11.5 version using semiautomatic segmentation method to calculate nasal volume after determining the nasal airway boundary. The subjects were grouped according to sagittal skeletal relation, craniofacial width, facial index, and facial form...
July 2016: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
C Duchemin, A Guertin, F Haddad, N Michel, V Métivier
Several terbium isotopes are suited for diagnosis or therapy in nuclear medicine. Tb-155 is of interest for SPECT imaging and/or Auger therapy. High radionuclide purity is mandatory for many applications in medicine. The quantification of the activity of the produced contaminants is therefore as important as that of the radionuclide of interest. The experiments performed at the ARRONAX cyclotron (Nantes, France), using the deuteron beam delivered up to 34MeV, provide an additional measurement of the excitation function of the Gd-nat(d,x)Tb-155 reaction and of the produced terbium and gadolinium contaminants...
September 30, 2016: Applied Radiation and Isotopes
V de C Machado, B R Chrcanovic, M B Felippe, L R C Manhães Júnior, P S P de Carvalho
The aim of this study was to verify the presence, spatial location, and calibre of the accessory canals (AC) of the canalis sinuosus by cone beam computed tomography, and their relationship to the anterior maxilla. This retrospective analysis included the scans of 1000 subjects. Parameters registered were sex, age, number of AC, presence or absence of AC with a diameter <1.0mm, AC diameter (only for AC with a diameter >1.0mm), and AC location in relation to the adjacent teeth. Males showed a statistically higher frequency of AC than females...
October 5, 2016: International Journal of Oral and Maxillofacial Surgery
N J R Hunter, C J L Wilson, V Luzin
Three techniques are used to measure crystallographic preferred orientations (CPO) in a naturally deformed quartz mylonite: transmitted light cross-polarized microscopy using an automated fabric analyser, electron backscatter diffraction (EBSD) and neutron diffraction. Pole figure densities attributable to crystal-plastic deformation are variably recognizable across the techniques, particularly between fabric analyser and diffraction instruments. Although fabric analyser techniques offer rapid acquisition with minimal sample preparation, difficulties may exist when gathering orientation data parallel with the incident beam...
September 22, 2016: Journal of Microscopy
L Witthauer, M Dieterle, S Abt, P Achenbach, F Afzal, Z Ahmed, J R M Annand, H J Arends, M Bashkanov, R Beck, M Biroth, N S Borisov, A Braghieri, W J Briscoe, F Cividini, S Costanza, C Collicott, A Denig, E J Downie, P Drexler, M I Ferretti-Bondy, S Gardner, S Garni, D I Glazier, D Glowa, W Gradl, M Günther, G M Gurevich, D Hamilton, D Hornidge, G M Huber, A Käser, V L Kashevarov, S Kay, I Keshelashvili, R Kondratiev, M Korolija, B Krusche, A B Lazarev, J M Linturi, V Lisin, K Livingston, S Lutterer, I J D MacGregor, J Mancell, D M Manley, P P Martel, V Metag, W Meyer, R Miskimen, E Mornacchi, A Mushkarenkov, A B Neganov, A Neiser, M Oberle, M Ostrick, P B Otte, D Paudyal, P Pedroni, A Polonski, S N Prakhov, A Rajabi, G Reicherz, G Ron, T Rostomyan, A Sarty, C Sfienti, M H Sikora, V Sokhoyan, K Spieker, O Steffen, I I Strakovski, Th Strub, I Supek, A Thiel, M Thiel, A Thomas, M Unverzagt, Yu A Usov, S Wagner, N K Walford, D P Watts, D Werthmüller, J Wettig, M Wolfes, L Zana
The double polarization observable E and the helicity dependent cross sections σ_{1/2} and σ_{3/2} were measured for η photoproduction from quasifree protons and neutrons. The circularly polarized tagged photon beam of the A2 experiment at the Mainz MAMI accelerator was used in combination with a longitudinally polarized deuterated butanol target. The almost 4π detector setup of the Crystal Ball and TAPS is ideally suited to detect the recoil nucleons and the decay photons from η→2γ and η→3π^{0}...
September 23, 2016: Physical Review Letters
V Gómez-Vallejo, A Lekuona, Z Baz, B Szczupak, U Cossío, J Llop
A simple, straightforward and efficient method for the synthesis of [(18)F]CF4 and [(18)F]SF6 based on an ion beam-induced isotopic exchange reaction is presented. Positron emission tomography ventilation studies in rodents using [(18)F]CF4 showed a uniform distribution of the radiofluorinated gas within the lungs and rapid elimination after discontinuation of the administration.
September 29, 2016: Chemical Communications: Chem Comm
H K Mohseni, D Cowan, D R Chettle, N D Priest, J Atanackovic, S H Byun, W V Prestwich
The time-dependent behaviour of sodium and chlorine was studied as a spinoff from a study of aluminum in the hand of subjects suffering from Alzheimer's disease and a control group, involving 15 Alzheimer's and 16 control subjects with an age range of 63-89 years. This was achieved using the in vivo neutron activation analysis system developed at McMaster University for the non-invasive measurement of aluminum, where a subject's hand is placed in a beam of accelerator-based thermalized neutrons, which activates elements by neutron capture...
October 6, 2016: Physiological Measurement
T G Borovskaya, A M Dygai, Yu A Shchemerova, S I Kamalova, V A Mashanova, A V Vychuzhanina, M E Poluektova, P G Madonov, D N Kinsht, V E Goldberg
Effectiveness of the granulocyte colony-stimulating factor immobilized by using electronbeam synthesis nanotechnology was investigated on the model of experimental testicular failure caused by the toxic effect on stem spermatogonia. Administration of the drug to experimental paclitaxel-treated animals increased the number of sources of the proliferative pool of spermatogenesis and its productivity. The effectiveness of immobilized granulocyte colony-stimulating factor was based on its ability to stimulate reparative regeneration of the spermatogenic tissue, which manifested in a decrease in spermatogenic layer maturity and increase in the number of microenvironment cells...
September 2016: Bulletin of Experimental Biology and Medicine
Ryan Beams, Luiz Gustavo Cancado, Sergiy Krylyuk, Irina Kalish, Berc Kalanyan, Arunima K Singh, Kamal Choudhary, Alina Bruma, Patrick M Vora, Francesca Tavazza, Albert V Davydov, Stephan J Stranick
We study the crystal symmetry of few-layer 1T' MoTe2 using the polarization dependence of the second harmonic generation (SHG) and Raman scattering. Bulk 1T' MoTe2 is known to be inversion symmetric; however, we find that the inversion symmetry is broken for finite crystals with even numbers of layers, resulting in strong SHG comparable to other transition metal dichalcogenides. Group theory analysis of the polarization dependence of the Raman signals allows for the definitive assignment of all the Raman modes in 1T' MoTe2 and clears up a discrepancy in the literature...
October 5, 2016: ACS Nano
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