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https://www.readbyqxmd.com/read/28633397/impact-of-a-refined-advanced-design-for-left-atrial-appendage-exclusion
#1
Gengo Sunagawa, Jamshid H Karimov, May Breitbach, Nicholas A Robinson, Kiyotaka Fukamachi
OBJECTIVES: Exclusion of the left atrial appendage has been proposed to reduce the risk of stroke in patients with atrial fibrillation. The aim of this study was to evaluate the feasibility and efficacy of the AtriClip PRO·V device (AOD2), now in development, for left atrial appendage exclusion in a canine model. METHODS: The newest AtriClip design comprises a dual-spring mechanism that allows the clip to open into a 'V' shape while still providing equivalent force along the length of the beam...
June 13, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28630486/integrated-optical-modulator-manipulating-the-polarization-and-rotation-handedness-of-orbital-angular-momentum-states
#2
S Faezeh Mousavi, Rahman Nouroozi, Giuseppe Vallone, Paolo Villoresi
Recent studies demonstrated that the optical channels encoded by Orbital Angular Momentum (OAM) are capable candidates for improving the next generation of communication systems. OAM states can enhance the capacity and security of high-dimensional communication channels in both classical and quantum regimes based on optical fibre and free space. Hence, fast and precise control of the beams encoded by OAM can provide their commercial applications in the compatible communication networks. Integrated optical devices are good miniaturized options to perform this issue...
June 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28626862/acoustic-field-characterization-of-a-clinical-magnetic-resonance-guided-high-intensity-focused-ultrasound-system-inside-the-magnet-bore
#3
Satya V V N Kothapalli, Michael B Altman, Ari Partanen, Leighton Wan, H Michael Gach, William Straube, Dennis E Hallahan, Hong Chen
PURPOSE: With the expanding clinical application of magnetic resonance-guided high intensity focused ultrasound (MR-HIFU), acoustic field characterization of MR-HIFU systems is needed for facilitating regulatory approval and ensuring consistent and safe power output of HIFU transducers. However, the established acoustic field measurement techniques typically use equipment that cannot be used in a magnetic resonance imaging (MRI) suite, thus posing a challenge to the development and execution of HIFU acoustic field characterization techniques...
June 19, 2017: Medical Physics
https://www.readbyqxmd.com/read/28621993/dark-matter-search-in-a-proton-beam-dump-with-miniboone
#4
A A Aguilar-Arevalo, M Backfish, A Bashyal, B Batell, B C Brown, R Carr, A Chatterjee, R L Cooper, P deNiverville, R Dharmapalan, Z Djurcic, R Ford, F G Garcia, G T Garvey, J Grange, J A Green, W Huelsnitz, I L de Icaza Astiz, G Karagiorgi, T Katori, W Ketchum, T Kobilarcik, Q Liu, W C Louis, W Marsh, C D Moore, G B Mills, J Mirabal, P Nienaber, Z Pavlovic, D Perevalov, H Ray, B P Roe, M H Shaevitz, S Shahsavarani, I Stancu, R Tayloe, C Taylor, R T Thornton, R Van de Water, W Wester, D H White, J Yu
The MiniBooNE-DM Collaboration searched for vector-boson mediated production of dark matter using the Fermilab 8-GeV Booster proton beam in a dedicated run with 1.86×10^{20} protons delivered to a steel beam dump. The MiniBooNE detector, 490 m downstream, is sensitive to dark matter via elastic scattering with nucleons in the detector mineral oil. Analysis methods developed for previous MiniBooNE scattering results were employed, and several constraining data sets were simultaneously analyzed to minimize systematic errors from neutrino flux and interaction rates...
June 2, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28619756/alpha-particle-enhanced-blood-brain-tumor-barrier-permeabilization-in-glioblastomas-using-integrin-alpha-v-beta-3-targeted-liposomes
#5
Anirudh Sattiraju, Xiaobing Xiong, Darpan N Pandya, Thaddeus J Wadas, Ang Xuan, Yao Sun, Youngkyoo Jung, Kiran Kumar Solingapuram Sai, Jay F Dorsey, King C Li, Akiva Mintz
<span style="font-size: 11.0pt; line-height: 200%; color: windowtext;">Glioblastoma (GBM) is the most common primary malignant astrocytoma characterized by extensive invasion, angiogenesis, hypoxia and micrometastasis. Despite the relatively leaky nature of GBM blood vessels, effective delivery of anti-tumor therapeutics has been a major challenge due to the complications caused by the blood brain barrier (BBB) and the highly torturous nature of newly formed tumor vasculature (blood tumor barrier-BTB)...
June 15, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28617607/structural-transformations-in-two-dimensional-transition-metal-dichalcogenide-mos2-under-electron-beam-insights-from-first-principles-calculations
#6
Silvan Kretschmer, Hannu-Pekka Komsa, Peter Boggild, Arkady V Krasheninnikov
The polymorphism of two-dimensional (2D) transition metal dichalcogenides (TMDs) and different electronic properties of the polymorphs make TMDs particularly promising materials in the context of the applications in electronics. Recently, local transformations from the semi- conducting trigonal prismatic H phase to the metallic octahedral T phase in 2D MoS2 have been induced by electron irradiation [Nat. Nanotech. 9 (2014) 391], but the mechanism of the transformations remains elusive. Using density functional theory calculations, we study the energetics of the stable and metastable phases of 2D MoS2 when additional charge, mechanical strain and vacancies are present...
June 15, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28611329/comparative-evaluation-of-shaping-ability-of-v-taper-2h-protaper-next-and-hyflex-cm-in-curved-canals-using-cone-beam-computed-tomography-an-in-vitro-study
#7
Pratima Ramakrishna Shenoi, Disha Anand Luniya, Gautam Pyarelal Badole, Chetana Sachin Makade, Rajesh Kubde, Rajiv Tarachand Khode
AIM: The aim of this study was to compare the canal transportation and canal centering ability in the preparation of curved root canals after instrumentation with V-Taper 2H, ProTaper Next (PN), and Hyflex CM files using cone-beam computed tomography (CBCT). MATERIALS AND METHODS: Thirty mesiobuccal canals of mandibular molars with an angle of curvature ranging from 20 to 40 were divided according to the instrument used in canal preparation into three groups of ten samples each: V-Taper 2H (Group 1), PN (Group 2), and Hyflex CM (Group 3)...
March 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28610691/radiological-properties-of-3d-printed-materials-in-kilovoltage-and-megavoltage-photon-beams
#8
O L Dancewicz, S R Sylvander, T S Markwell, S B Crowe, J V Trapp
PURPOSE: This study evaluates the radiological properties of different 3D printing materials for a range of photon energies, including kV and MV CT imaging and MV radiotherapy beams. METHODS: The CT values of a number of materials were measured on an Aquilion One CT scanner at 80kVp, 120kVp and a Tomotherapy Hi Art MVCT imaging beam. Attenuation of the materials in a 6MV radiotherapy beam was investigated. RESULTS: Plastic filaments printed with various infill densities have CT values of -743±4, -580±1 and -113±3 in 120kVp CT images which approximate the CT values of low-density lung, high-density lung and soft tissue respectively...
June 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28610690/investigating-output-and-energy-variations-and-their-relationship-to-delivery-qa-results-using-statistical-process-control-for-helical-tomotherapy
#9
Diana Binny, Emilio Mezzenga, Craig M Lancaster, Jamie V Trapp, Tanya Kairn, Scott B Crowe
The aims of this study were to investigate machine beam parameters using the TomoTherapy quality assurance (TQA) tool, establish a correlation to patient delivery quality assurance results and to evaluate the relationship between energy variations detected using different TQA modules. TQA daily measurement results from two treatment machines for periods of up to 4years were acquired. Analyses of beam quality, helical and static output variations were made. Variations from planned dose were also analysed using Statistical Process Control (SPC) technique and their relationship to output trends were studied...
June 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28608445/tailoring-the-volatility-and-stability-of-oligopeptides
#10
J Schätti, U Sezer, S Pedalino, J P Cotter, M Arndt, M Mayor, V Köhler
Amino acids are essential building blocks of life and fluorinated derivatives have gained interest in chemistry and medicine. Modern mass spectrometry has enabled the study of oligo- and polypeptides as isolated entities in the gas phase, but predominantly as singly or even multiply charged species. While laser desorption of neutral peptides into adiabatically expanding supersonic noble gas jets is possible, UV-VIS spectroscopy, electric or magnetic deflectometry as well as quantum interferometry would profit from the possibility to prepare thermally slow molecular beams...
June 12, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28602092/in-situ-observation-of-oxygen-vacancy-dynamics-and-ordering-in-the-epitaxial-lacoo3-system
#11
Jae Hyuck Jang, Young-Min Kim, Qian He, Rohan Mishra, Liang Qiao, Michael D Biegalski, Andrew R Lupini, Sokrates T Pantelides, Stephen J Pennycook, Sergei V Kalinin, Albina Y Borisevich
Vacancy dynamics and ordering underpin the electrochemical functionality of complex oxides and strongly couple to their physical properties. In the field of the epitaxial thin films, where connection between chemistry and film properties can be most clearly revealed, the effects related to oxygen vacancies are attracting increasing attention. In this paper, we report a direct, real-time, atomic level observation of the formation of oxygen vacancies in the epitaxial LaCoO3 thin films and heterostructures under the influence of the electron beam utilizing scanning transmission electron microscopy (STEM)...
June 11, 2017: ACS Nano
https://www.readbyqxmd.com/read/28598677/e2-decay-strength-of-the-m1-scissors-mode-of-156-gd-and-its-first-excited-rotational-state
#12
T Beck, J Beller, N Pietralla, M Bhike, J Birkhan, V Derya, U Gayer, A Hennig, J Isaak, B Löher, V Yu Ponomarev, A Richter, C Romig, D Savran, M Scheck, W Tornow, V Werner, A Zilges, M Zweidinger
The E2/M1 multipole mixing ratio δ_{1→2} of the 1_{sc}^{+}→2_{1}^{+} γ-ray decay in ^{156}Gd and hence the isovector E2 transition rate of the scissors mode of a well-deformed rotational nucleus has been measured for the first time. It has been obtained from the angular distribution of an artificial quasimonochromatic linearly polarized γ-ray beam of energy 3.07(6) MeV scattered inelastically off an isotopically highly enriched ^{156}Gd target. The data yield first direct support for the deformation dependence of effective proton and neutron quadrupole boson charges in the framework of algebraic nuclear models...
May 26, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28598675/chirp-mitigation-of-plasma-accelerated-beams-by-a-modulated-plasma-density
#13
R Brinkmann, N Delbos, I Dornmair, M Kirchen, R Assmann, C Behrens, K Floettmann, J Grebenyuk, M Gross, S Jalas, T Mehrling, A Martinez de la Ossa, J Osterhoff, B Schmidt, V Wacker, A R Maier
Plasma-based accelerators offer the possibility to drive future compact light sources and high-energy physics applications. Achieving good beam quality, especially a small beam energy spread, is still one of the major challenges. Here, we propose to use a periodically modulated plasma density to shape the longitudinal fields acting on an electron bunch in the linear wakefield regime. With simulations, we demonstrate an on-average flat accelerating field that maintains a small beam energy spread.
May 26, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28595774/feasibility-of-using-single-photon-counting-x-ray-for-lung-tumor-position-estimation-based-on-4d-ct
#14
Katharina P Aschenbrenner, Christian V Guthier, Yulia Lyatskaya, Judit Boda-Heggemann, Frederik Wenz, Jürgen W Hesser
PURPOSE: In stereotactic body radiation therapy of lung tumors, reliable position estimation of the tumor is necessary in order to minimize normal tissue complication rate. While kV X-ray imaging is frequently used, continuous application during radiotherapy sessions is often not possible due to concerns about the additional dose. Thus, ultra low-dose (ULD) kV X-ray imaging based on a single photon counting detector is suggested. This paper addresses the lower limit of photons to locate the tumor reliably with an accuracy in the range of state-of-the-art methods, i...
June 5, 2017: Zeitschrift Für Medizinische Physik
https://www.readbyqxmd.com/read/28593033/acoustic-radiation-force-of-a-quasi-gaussian-beam-on-an-elastic-sphere-in-a-fluid
#15
A V Nikolaeva, O A Sapozhnikov, M R Bailey
Acoustic radiation force has many applications. One of the related technologies is the ability to noninvasively expel stones from the kidney. To optimize the procedure it is important to develop theoretical approaches that can provide rapid calculations of the radiation force depending in stone size and elastic properties, together with ultrasound beam diameter, intensity, and frequency. We hypothesize that the radiation force nonmonotonically depends on the ratio between the acoustic beam width and stone diameter because of coupling between the acoustic wave in the fluid and shear waves in the stone...
September 2016: IEEE International Ultrasonics Symposium: [proceedings]
https://www.readbyqxmd.com/read/28586136/benchmarking-geant4-hadronic-models-for-prompt-%C3%AE-monitoring-in-carbon-ion-therapy
#16
Marie Vanstalle, Christian Finck, Ilaria Mattei, Alessio Sarti, Erika De Lucia, Luca Piersanti, Fabio Bellini, Francesco Collamati, Riccardo Faccini, Fernando Ferroni, Vincenzo Patera, Adalberto Sciubba, Giacomo Traini, Cecilia Voena, Fabiano Bini, Marco Durante, Marta Rovitus, Christoph Schuy, Salvatore Fiore, Michela Marafini, Chiara La Tessa
PURPOSE: The real-time monitoring of the spread-out Bragg peak would allow the planned dose delivered during treatment to be directly verified, but this poses a major challenge in modern ion beam therapy. A possible method to achieve this goal is to exploit the production of secondary particles by the nuclear reactions of the beam with the patient and correlate their emission profile to the planned target volume position. In this study, we present both the production rate and energy spectra of the prompt-γ produced by the interactions of the (12) C ion beam with a polymethyl methacrylate (PMMA) target...
June 6, 2017: Medical Physics
https://www.readbyqxmd.com/read/28581778/gamma-decay-of-unbound-neutron-hole-states-in-133-sn
#17
V Vaquero, A Jungclaus, P Doornenbal, K Wimmer, A Gargano, J A Tostevin, S Chen, E Nácher, E Sahin, Y Shiga, D Steppenbeck, R Taniuchi, Z Y Xu, T Ando, H Baba, F L Bello Garrote, S Franchoo, K Hadynska-Klek, A Kusoglu, J Liu, T Lokotko, S Momiyama, T Motobayashi, S Nagamine, N Nakatsuka, M Niikura, R Orlandi, T Saito, H Sakurai, P A Söderström, G M Tveten, Zs Vajta, M Yalcinkaya
Excited states in the nucleus ^{133}Sn, with one neutron outside the double magic ^{132}Sn core, were populated following one-neutron knockout from a ^{134}Sn beam on a carbon target at relativistic energies at the Radioactive Isotope Beam Factory at RIKEN. Besides the γ rays emitted in the decay of the known neutron single-particle states in ^{133}Sn additional γ strength in the energy range 3.5-5.5 MeV was observed for the first time. Since the neutron-separation energy of ^{133}Sn is low, S_{n}=2.402(4)  MeV, this observation provides direct evidence for the radiative decay of neutron-unbound states in this nucleus...
May 19, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28581770/collimated-propagation-of-fast-electron-beams-accelerated-by-high-contrast-laser-pulses-in-highly-resistive-shocked-carbon
#18
X Vaisseau, A Morace, M Touati, M Nakatsutsumi, S D Baton, S Hulin, Ph Nicolaï, R Nuter, D Batani, F N Beg, J Breil, R Fedosejevs, J-L Feugeas, P Forestier-Colleoni, C Fourment, S Fujioka, L Giuffrida, S Kerr, H S McLean, H Sawada, V T Tikhonchuk, J J Santos
Collimated transport of ultrahigh intensity electron current was observed in cold and in laser-shocked vitreous carbon, in agreement with simulation predictions. The fast electron beams were created by coupling high-intensity and high-contrast laser pulses onto copper-coated cones drilled into the carbon samples. The guiding mechanism-observed only for times before the shock breakout at the inner cone tip-is due to self-generated resistive magnetic fields of ∼0.5-1  kT arising from the intense currents of fast electrons in vitreous carbon, by virtue of its specific high resistivity over the range of explored background temperatures...
May 19, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28581404/treatment-related-toxicity-in-patients-with-early-stage-non-small-cell-lung-cancer-and-coexisting-interstitial-lung-disease-a-systematic-review
#19
REVIEW
Hanbo Chen, Suresh Senan, Esther J Nossent, R Gabriel Boldt, Andrew Warner, David A Palma, Alexander V Louie
PURPOSE: Definitive treatment for patients with early-stage non-small cell lung cancer (ES-NSCLC) is usually well tolerated. Patients with ES-NSCLC and coexisting interstitial lung disease (ILD) are at increased risk of severe treatment-related toxicity after definitive therapy. The main objective of this systematic review is to provide a pooled estimation of treatment-related mortality and ILD-specific toxicity in this population of patients and to identify trends for further study. METHODS AND MATERIALS: The MEDLINE and Embase databases were queried from respective dates of inception to January 2016...
July 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28580331/beam-collimation-during-lumbar-spine-radiography-a-retrospective-study
#20
V Karami, M Zabihzadeh
INTRODUCTION: Collimating the primary beam to the area of diagnostic interest (ADI) has been strongly recommended as an effective method to reduce patient's radiation dose and to improve image quality during radiology practice. Lack or inadequate collimation results in excessive radiation dose to patients and deterioration image quality. OBJECTIVE: To assess the quality of beam collimation during lumbar spine radiography at two general hospitals in Ahvaz, Iran. MATERIALS AND METHODS: We retrospectively reviewed 830 digital antero-posterior (AP) lumbar spine radiographs in term of beam collimation...
June 2017: Journal of Biomedical Physics & Engineering
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