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https://www.readbyqxmd.com/read/29690499/levels-of-soluble-endothelium-adhesion-molecules-and-complications-among-sickle-cell-disease-patients-in-ghana
#1
Charles Antwi-Boasiako, Eric S Donkor, Fredericka Sey, Bartholomew Dzudzor, Gifty B Dankwah, Kate H Otu, Alfred Doku, Campbell A Dale, Ivy Ekem
BACKGROUND: Soluble adhesion molecules are involved in the gathering and joining of inflammatory cells to vascular endothelium. Therefore, they serve as potential markers of endothelial dysfunction in vascular diseases including sickle cell disease (SCD). In Ghana, there are scarcely any report on the levels of adhesion molecules among SCD patients. The current study aimed to determine plasma levels of ICAM-1, VCAM-1 and E-Selectin as markers of endothelial dysfunction in SCD patients in steady state, complications and controls...
April 21, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/29687468/spontaneous-detumescence-and-full-restoration-of-erection-in-a-patient-with-high-flow-priapism-with-persistent-arterial-lacunar-fistula-after-repeated-selective-embolisation-a-case-report
#2
M Čechová, R Pádr, P Hanek, M Chocholatý
High-flow priapism is a rare condition mainly caused by perineal trauma. Laceration of cavernosal artery results in a formation of arterial-lacunar fistula with unregulated blood flow causing prolonged erection. We present a case of a 25-year-old man with high-flow priapism and concurrent erectile dysfunction treated with repeated selective embolisation with only a partial effect. When no further embolisation was possible, we assumed on conservative management even through the fistula was still present. Spontaneous detumescence occurred 9 months, and erectile function has fully restored 24 months after the injury...
April 23, 2018: Andrologia
https://www.readbyqxmd.com/read/29666039/comment-on-olanzapine-induced-priapism-in-a-child-with-asperger-s-syndrome
#3
Mete Özkıdık, Anar İbrahimov
No abstract text is available yet for this article.
April 15, 2018: Balkan Medical Journal
https://www.readbyqxmd.com/read/29614630/blood-rheological-abnormalities-in-sickle-cell-anemia
#4
Philippe Connes, Céline Renoux, Marc Romana, Manouk Abkarian, Philippe Joly, Cyril Martin, Marie-Dominique Hardy-Dessources, Samir K Ballas
This review focuses on the contribution of abnormal blood rheology in the pathophysiology of sickle cell anemia (SCA). SCA is characterized by a reduction of red blood cell (RBC) deformability but this reduction is very heterogeneous among patients. Recent works have shown that patients with the lowest RBC deformability (measured by ektacytometry) have enhanced hemolysis and would be more prone to develop several complications such as priapism, leg ulcers and glomerulopathy. In contrast, patients with the highest deformability, and not under hydroxyurea therapy, seem to develop more frequently vaso-occlusive like events...
2018: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/29607523/a-new-cause-of-ischaemic-priapism-synthetic-cannabinoids
#5
M Ortac, Y Pazır, A Kadıoğlu
Priapism is a urological emergency that needs early intervention and may lead to irreversible cavernosal damage. Ischaemic priapism is the most common type, which is frequently idiopathic and commonly associated with haematological diseases, medications or recreational drugs. Synthetic cannabinoids (SCs) have been increasingly used all over the world, particularly among young-adult population. SCs can cause severe adverse effects on several organ systems. However, there are no studies in the literature which have stated the possible relationship between using of SCs and priapism...
April 1, 2018: Andrologia
https://www.readbyqxmd.com/read/29601467/posttraumatic-high-flow-nonischemic-priapism
#6
Ismail Nalbant, Can Tuygun, Adnan Gücük, Isik Conkbayir, Ufuk Oztürk, Muhammed Sahin Yilmaz, Muhammed Abdurrahim İmamoglu
Priapism is an uncommon disorder, and nonischemic priapism is seen less frequently in children, generally after trauma. Although it seems to be an advantage that urgent intervention is not required because of no cavernous ischemia, it is likely to be misdiagnosed because of the asymptomatic potential. We aimed to present a case of posttraumatic nonischemic priapism.
April 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29587411/relationship-between-response-to-pde5-inhibitors-and-penile-duplex-doppler-ultrasound-in-erectile-dysfunction
#7
Ercan Ogreden, Ural Oğuz, Erhan Demirelli, Alptekin Tosun, Orhan Yalçın
The relationship between the results of penile duplex Doppler ultrasound (PDDU) and response to vardenafil was investigated in patients diagnosed with erectile dysfunction (ED). Data from 148 patients with ED were analyzed retrospectively. Patients who did not respond to therapy were classified in to Group I ( n = 32), those who responded partially were classified into Group II ( n = 40), and complete responders were classified into Group III ( n = 76). Age, comorbidities, and vascular and penile pathologies were compared among the three groups...
March 26, 2018: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29578404/priapism-and-hemodialysis-case-report-and-literature-review
#8
Weiwen Vivian Shih, Cynthia Wong
BACKGROUND: Priapism is a known but rarely described complication of patients on dialysis. The incidence of priapism in the general population is estimated at 1.5 in 100,000 patients and 2.9 in 100,000 patients in males over 40 years of age; however there is little current literature describing priapism in adult dialysis patients and no current literature in pediatric dialysis patients [1]. We describe two pediatric patients who developed priapism concurrent with hemodialysis, each with differing severity and therapeutic management...
March 26, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29553994/the-risks-of-using-herbal-supplements-for-sexual-dysfunction-associated-with-psychotropic-medications-a-case-report-of-extenze-use-and-priapism
#9
Jooyeon Lee, Joe Hong, Norma Dunn, Richard Gersh, Ronnie Swift
No abstract text is available yet for this article.
March 16, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29550463/penoscrotal-decompression-promising-new-treatment-paradigm-for-refractory-ischemic-priapism
#10
Joceline S Fuchs, Nabeel Shakir, Maxim J McKibben, Shawn Mathur, Sloan Teeple, Jeremy M Scott, Allen F Morey
BACKGROUND: For prolonged ischemic priapism, outcomes after distal shunt are poor, with only 30% success for priapic episodes lasting longer than 48 hours. AIM: To present a novel, glans-sparing approach of corporal decompression through a penoscrotal approach for cases of refractory ischemic priapism (RIP) after failed distal shunt procedures. METHODS: We describe the technique and present our initial experience with penoscrotal decompression (PSD) for treatment of RIP after failed distal shunt...
March 14, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29547365/management-of-priapism-with-a-trial-of-exercise-in-the-emergency-department
#11
Jonathan Gravel, Constance LeBlanc, Catherine Varner
Priapism is characterized by persistent penile erection in the absence of sexual arousal or desire that does not subside with orgasm. Although relatively uncommon, it is a genitourinary emergency that necessities prompt work-up and appropriate management, as there is a time-dependent relationship between total duration of erection and an increasing risk of permanent erectile dysfunction. Confirming the type of priapism is key to proper management, but the majority of cases presenting to the emergency department are ischemic in nature...
March 16, 2018: CJEM
https://www.readbyqxmd.com/read/29508322/-priapism
#12
REVIEW
Julian Marcon, C G Stief, A Becker
No abstract text is available yet for this article.
March 2018: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/29479984/the-role-of-apoptosis-and-the-effect-of-epidermal-growth-factor-on-proapoptotic-bnip-3-in-an-experimental-rat-priapism-model
#13
Osman Barut, Ahmet Karakeçi, Tunç Ozan, Fatih Fırdolaş, Necip Pirinçci, İrfan Orhan
Background/aim: This study aimed to investigate the effects of apoptosis-inducing Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP 3) and antiapoptotic epidermal growth factor (EGF) on the pathophysiology of experimental low-flow priapism. Materials and methods: Twenty-four adult Sprague-Dawley rats were divided into four equal groups. Group I was the control group. Ischemic priapism was induced for 4 h in Group II rats. In Group III, intraperitoneal EGF at 10 µg/kg was given for 7 days before induction of ischemic priapism for 4 h...
February 23, 2018: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29463473/poorly-controlled-homocystinuria-a-rare-cause-of-ischemic-priapism
#14
Mark Johnson, Elaine Murphy, Amr Raheem, David Ralph
We report on the 1st case of ischemic priapism secondary to poorly controlled homocystinuria. Homocystinuria is a rare, autosomal recessive, inherited disorder of metabolism that is caused by a deficiency of cystathionine synthase, leading to marked hyperhomocysteinemia. Arterial and/or venous thromboemboli are a major cause of mortality and morbidity in patients with homocystinuria. Untreated patients have a 50% chance of having a vascular event by 30 years of age. Increased homocysteine levels have been reported to upregulate prothrombotic factors and downregulate antithrombotic factors; in particular, increased homocystinuria has been found to downregulate nitric oxide (NO)...
February 17, 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29454716/emergency-management-of-priapism-in-the-united-kingdom-a-survey-of-current-practice
#15
Nicholas Bullock, Martin Steggall, Gareth Brown
BACKGROUND: Despite its importance, current practice in the emergency management of priapism in the United Kingdom is unknown. AIM: To evaluate current practice in the emergency management of priapism in the United Kingdom. METHODS: All "full," "associate urological specialist," and "trainee" members of the British Association of Urological Surgeons (BAUS; leading membership-based organization for practitioners of urologic surgery in the United Kingdom) were invited to participate in an online survey...
February 14, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29430118/penile-metastasis-from-prostate-cancer-presenting-as-malignant-priapism-detected-using-gallium-68-prostate-specific-membrane-antigen-positron-emission-tomography-computed-tomography
#16
Koramadai Karuppusamy Kamaleshwaran, Barani Kumar Pollachi Balasundararaj, Raghi Jose, Ajit Sugunan Shinto
Gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography (Ga-68 PSMA PET/CT) is a promising diagnostic tool for patients with prostate cancer. Penile metastasis from prostate cancer is a rare phenomenon that infrequently manifests as malignant priapism. We present a case of 79-year-old patient diagnosed as a case of adenocarcinoma prostate presenting with penile metastases imaged using Ga-68 PSMA PET/CT.
January 2018: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29417263/superselective-transcatheter-artery-embolization-in-patients-with-non-ischemic-priapism
#17
Renguang Pei, Min Yang, Chao Wang, Jian Wang, Xiaoqiang Tong, Yinghua Zou
PURPOSE: To investigate the efficacy and safety of superselective transcatheter artery embolization in patients with non-ischemic priapism. MATERIALS AND METHODS: We retrospectively reviewed a cohort of 17 consecutive patients with non-ischemic priapism from September 2006 to August 2017. The median follow-up time was 8 months. RESULTS: Sixteen patients underwent superselective transcatheter artery embolization, and all had complete resolution of non-ischemic priapism...
February 7, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29416825/prognosis-of-men-with-penile-metastasis-and-malignant-priapism-a-systematic-review
#18
REVIEW
Andrea Cocci, Oliver W Hakenberg, Tommaso Cai, Gabriella Nesi, Lorenzo Livi, Beatrice Detti, Andrea Minervini, Girolamo Morelli, Marco Carini, Sergio Serni, Mauro Gacci
Metastases to the penis are rare, but can have severe consequences. The aim of this study was to systematically review the literature in order to gain more information on the presentation and prognosis of this metastatic disease. We reviewed the literature relating to all case reports, series and reviews about penile metastasis, from 2003 to 2013, through a Medline search. We identified 63 articles and 69 patients. Metastases were located on the root (38.8%), the shaft (38.8%) or the glans (22.2%) of the penis...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29414500/priapism-as-the-initial-sign-in-hematologic-disease-case-report-and-literature-review
#19
Luis Cuitláhuac Becerra-Pedraza, Luis Enrique Jiménez-Martínez, Iran Peña-Morfin, Rogelio Nava-Esquivel, Juan Alfredo Villegas-Martínez
INTRODUCTION: Priapism is an uncommon sign and sometimes considered a diagnosis challenge into systemic disease; this is defined as ≥4 h continuous penile erection, without sexual stimulation. We state that this work has been reported in line with the SCARE criteria PRESENTATION OF CASE: A Mexican 52-year-old man was brought to the emergency room with priapism of six days of evolution. His medical history reported fatigue and waxy pallor had begun a month ago, the rest of interrogation was unremarked...
January 12, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29406065/urologic-emergencies
#20
REVIEW
Adarsh S Manjunath, Matthias D Hofer
Urologic emergencies can involve the kidneys, ureters, bladder, urethra, penis, scrotum, or testicles. History and physical examination are essential to diagnosis, whereas imaging is increasingly used to confirm diagnoses. Acute urinary retention should be relieved with Foley placement. Penile emergencies include paraphimosis, which can be treated by foreskin reduction, whereas penile fracture and priapism require urologic intervention. Fournier gangrene and testicular torsion are scrotal emergencies requiring emergent surgery...
March 2018: Medical Clinics of North America
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