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https://www.readbyqxmd.com/read/29430118/penile-metastasis-from-prostate-cancer-presenting-as-malignant-priapism-detected-using-gallium-68-prostate-specific-membrane-antigen-positron-emission-tomography-computed-tomography
#1
Koramadai Karuppusamy Kamaleshwaran, Barani Kumar Pollachi Balasundararaj, Raghi Jose, Ajit Sugunan Shinto
Gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography (Ga-68 PSMA PET/CT) is a promising diagnostic tool for patients with prostate cancer. Penile metastasis from prostate cancer is a rare phenomenon that infrequently manifests as malignant priapism. We present a case of 79-year-old patient diagnosed as a case of adenocarcinoma prostate presenting with penile metastases imaged using Ga-68 PSMA PET/CT.
January 2018: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29417263/superselective-transcatheter-artery-embolization-in-patients-with-non-ischemic-priapism
#2
Renguang Pei, Min Yang, Chao Wang, Jian Wang, Xiaoqiang Tong, Yinghua Zou
PURPOSE: To investigate the efficacy and safety of superselective transcatheter artery embolization in patients with non-ischemic priapism. MATERIALS AND METHODS: We retrospectively reviewed a cohort of 17 consecutive patients with non-ischemic priapism from September 2006 to August 2017. The median follow-up time was 8 months. RESULTS: Sixteen patients underwent superselective transcatheter artery embolization, and all had complete resolution of non-ischemic priapism...
February 7, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29416825/prognosis-of-men-with-penile-metastasis-and-malignant-priapism-a-systematic-review
#3
REVIEW
Andrea Cocci, Oliver W Hakenberg, Tommaso Cai, Gabriella Nesi, Lorenzo Livi, Beatrice Detti, Andrea Minervini, Girolamo Morelli, Marco Carini, Sergio Serni, Mauro Gacci
Metastases to the penis are rare, but can have severe consequences. The aim of this study was to systematically review the literature in order to gain more information on the presentation and prognosis of this metastatic disease. We reviewed the literature relating to all case reports, series and reviews about penile metastasis, from 2003 to 2013, through a Medline search. We identified 63 articles and 69 patients. Metastases were located on the root (38.8%), the shaft (38.8%) or the glans (22.2%) of the penis...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29414500/priapism-as-the-initial-sign-in-hematologic-disease-case-report-and-literature-review
#4
Luis Cuitláhuac Becerra-Pedraza, Luis Enrique Jiménez-Martínez, Iran Peña-Morfin, Rogelio Nava-Esquivel, Juan Alfredo Villegas-Martínez
INTRODUCTION: Priapism is an uncommon sign and sometimes considered a diagnosis challenge into systemic disease; this is defined as ≥4 h continuous penile erection, without sexual stimulation. We state that this work has been reported in line with the SCARE criteria PRESENTATION OF CASE: A Mexican 52-year-old man was brought to the emergency room with priapism of six days of evolution. His medical history reported fatigue and waxy pallor had begun a month ago, the rest of interrogation was unremarked...
January 12, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29406065/urologic-emergencies
#5
REVIEW
Adarsh S Manjunath, Matthias D Hofer
Urologic emergencies can involve the kidneys, ureters, bladder, urethra, penis, scrotum, or testicles. History and physical examination are essential to diagnosis, whereas imaging is increasingly used to confirm diagnoses. Acute urinary retention should be relieved with Foley placement. Penile emergencies include paraphimosis, which can be treated by foreskin reduction, whereas penile fracture and priapism require urologic intervention. Fournier gangrene and testicular torsion are scrotal emergencies requiring emergent surgery...
March 2018: Medical Clinics of North America
https://www.readbyqxmd.com/read/29405906/case-temporary-chemical-castration-in-the-management-of-recurrent-priapism
#6
Yooni Yi
No abstract text is available yet for this article.
February 6, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/29394072/molecular-profile-of-priapism-associated-with-low-nitric-oxide-bioavailability
#7
Justin D La Favor, Zongming Fu, Vidya Venkatraman, Trinity J Bivalacqua, Jennifer E Van Eyk, Arthur L Burnett
Priapism is a disorder in which prolonged penile erection persists uncontrollably, potentially leading to tissue damage. Priapism commonly afflicts patient populations with severely low nitric oxide (NO) bioavailability. As NO is a primary mediator of erection, the molecular mechanisms involved in priapism pathophysiology associated with low NO bioavailability are not well understood. The objective of this study was to identify dysregulated molecular targets and signaling pathways in penile tissue of a mouse model of low NO bioavailability that have potential relevance to priapism...
February 2, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29375820/recent-advances-in-the-management-of-priapism
#8
REVIEW
Asif Muneer, Hussain M Alnajjar, David Ralph
Priapism is an uncommon urological emergency that can lead to permanent impotence if prompt presentation and medical intervention is not performed. It is a breakdown of the usual physiological mechanisms controlling penile tumescence and detumescence, leading to a prolonged penile erection (>4 hours) that is unrelated to sexual stimulation. Currently, there are three accepted subtypes: ischaemic, non-ischaemic, and stuttering priapism, which is also known as recurrent ischemic priapism. The aim of treatment is the immediate resolution of the painful erection and the preservation of cavernosal smooth muscle function in order to prevent cavernosal fibrosis, which can lead to penile shortening and permanent erectile dysfunction...
2018: F1000Research
https://www.readbyqxmd.com/read/29357203/baus-consensus-document-for-the-management-of-male-genital-emergencies-priapism
#9
REVIEW
A Muneer, G Brown, T Dorkin, M Lucky, R Pearcy, M Shabbir, C J Shukla, R W Rees, D J Summerton
Male genital emergencies relating to the penis and scrotum are rare and require prompt investigation and surgical intervention. Clinicians are often unfamiliar with the management of these conditions and may not work in a specialist centre with on-site expertise in genitourethral surgery available. A series of consensus statements have been developed by an expert consensus comprising BAUS Section of Andrology and Genitourethral Surgery together with experts from units throughout the UK. Priapism requires prompt assessment and treatment and this series of consensus statements provide guidance for UK practice...
January 22, 2018: BJU International
https://www.readbyqxmd.com/read/29354506/inflatable-penile-prosthesis-implant-length-with-baseline-characteristic-correlations-preliminary-analysis-of-the-propper-study
#10
Nelson Bennett, Gerard Henry, Edward Karpman, William Brant, LeRoy Jones, Mohit Khera, Tobias Kohler, Brian Christine, Eugene Rhee, Bryan Kansas, Anthony J Bella
Background: "Prospective Registry of Outcomes with Penile Prosthesis for Erectile Restoration" (PROPPER) is a large, multi-institutional, prospective clinical study to collect, analyze, and report real-world outcomes for men implanted with penile prosthetic devices. We prospectively correlated co-morbid conditions and demographic data with implanted penile prosthesis size to enable clinicians to better predict implanted penis size following penile implantation. We present many new data points for the first time in the literature and postulate that radical prostatectomy (RP) is negatively correlated with penile corporal length...
December 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29332554/evaluating-the-dose-dependent-mechanism-of-action-of-trazodone-by-estimation-of-occupancies-for-different-brain-neurotransmitter-targets
#11
Luca Settimo, David Taylor
Trazodone is a drug that was introduced in the clinic almost 40 years ago. It is licensed to treat depression, but it is also commonly used off-label to treat insomnia. A recent study shows that it could be promising in preventing neurodegeneration in mice, and clinical trials to assess its possible beneficial effects on dementia and Alzheimer's disease are expected to start soon in humans. In this study, we describe the dose-dependent pharmacology of trazodone by carrying out pharmacokinetic simulations aiming to predict the brain concentrations of trazodone for different drug-dosing regimens and calculating occupancy for 28 different targets for which published trazodone-binding data are available...
January 2018: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29305941/traumatic-urethraggia-in-adolescence-ushering-in-the-new-age-of-extreme-sports
#12
I Hodge, A Adam, M Chennapragada, A Tiu, A V Deshpande
Herein we describe a case of a 14-year-old with straddle injury to the base of the penis, sustained during an indoor rock climbing accident, who presented with severe urethrragia. Urethral injury was confirmed with retrograde urethrography. The patient became haemodynamically unstable from persistent blood loss, and corporal arterial injury was diagnosed on CT angiography. The urethraggia was successfully controlled with angioembolisation. The unique aspects of this case were the challenges in establishing the diagnosis on the background of the abnormal presentation of vascular injury of blood loss as opposed to painless priapism...
January 3, 2018: Urology
https://www.readbyqxmd.com/read/29299902/role-of-penile-prosthesis-in-priapism-a-review
#13
REVIEW
Amit G Reddy, Laith M Alzweri, Andrew T Gabrielson, Gabriel Leinwand, Wayne J G Hellstrom
Ischemic priapism is a urological emergency that has been associated with long-standing and irreversible adverse effects on erectile function. Studies have demonstrated a linear relationship between the duration of critically ischemic episodes and the subsequent development of corporal fibrosis and irreversible erectile function loss. Placement of a penile prosthesis is a well-established therapeutic option for the management of erectile dysfunction secondary to ischemic priapism, and will be the focus of this review...
January 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29278308/effect-of-lysyl-oxidase-lox-on-corpus-cavernous-fibrosis-caused-by-ischaemic-priapism
#14
Liang Gao, Changjing Wu, Fudong Fu, Xuanhe You, Xue Ma, Feng Qin, Tao Li, Run Wang, Jiuhong Yuan
Penile fibrosis caused by ischemic priapism (IP) adversely affects patients' erectile function. We explored the role of lysyl oxidase (LOX) in rat and human penes after ischemic priapism (IP) to verify the effects of anti-LOX in relieving penile fibrosis and preventing erectile dysfunction caused by IP in rats. Seventy-two rats were randomly divided into six groups: control group, control + β-aminopropionitrile (BAPN) group, 9 hrs group, 9 hrs + BAPN group, 24 hrs group, and 24 hrs + BAPN group. β-aminopropionitrile (BAPN), a specific inhibitor of LOX, was administered in the drinking water...
December 26, 2017: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29239397/challenges-surrounding-penile-prostheses-insertion-following-acute-priapism
#15
EDITORIAL
Alex Tatem, Jason R Kovac
No abstract text is available yet for this article.
November 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29238659/the-use-of-penile-prostheses-in-the-management-of-priapism
#16
REVIEW
Jonathan Moore, Thomas F Whelan, Gavin M Langille
Priapism is a relatively uncommon condition that can result in erectile dysfunction (ED) and corporal fibrosis. Cases of prolonged priapism are particularly prone to ED, which arises when priapism is treatment refractory or had a delayed presentation. Due to the emergent nature of priapism, it behooves urologists to be familiar with all potential treatment modalities to minimize adverse outcomes. In this review paper, we aim to summarize the literature regarding the use of penile prosthesis (PP) implantation in the setting of ischemic priapism (IP)...
November 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29230262/-cavernous-metastasis-from-blader-tumor
#17
Mohammed Alae Touzani, Othmane Yddoussalah
The incidence of cavernous metastases after radical treatment for bladder tumor is exceptional and is approximately 1%. The mean time between surgery and the occurrence of metastases is 8 months. In some cases they occur after 10 years. Diagnosis is confirmed by biopsy, which shows their urothelial origin. Here we report the case of 56-year old patient, with a history of smoking, having undergone total cystoprostatectomy in January 2017, who presented 2 months later with induratio penis plastica with no other sign associated...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29222429/case-report-ischemic-priapism-secondary-to-tinzaparin
#18
Jennifer Purnell, Alym N Abdulla
Low-molecular-weight heparin (LMWH) therapy has recently been proposed as a cause of ischemic priapism. The evidence, however, remains scarce, as there are very few published cases of LMWH-induced priapism to date. The implications of such events are significant as ischemic priapism is a medical emergency. In current clinical practice we are seeing a trend towards LMWH therapies replacing unfractionated heparin (UFH). As LMWH therapies continue to gain favor, we will potentially see more cases of LMWH-induced priapism...
December 8, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29208538/sleep-related-painful-erections-a-meta-analysis-on-the-pathophysiology-and-risks-and-benefits-of-medical-treatments
#19
REVIEW
Sanne Vreugdenhil, Alida Cornelia Weidenaar, Igle Jan de Jong, Mels Frank van Driel
BACKGROUND: Patients with sleep-related painful erections (SRPEs) have frequent awakenings from deep penile pain during nocturnal erections. This results in severe sleep deprivation. AIM: To review the current literature on SRPEs and discuss the pathophysiologic theories and risks and benefits of medical treatments. METHODS: PubMed was searched using the terms sleep-related painful erections, nocturnal priapism, treatment, and sleep-related erections...
December 2, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29201505/is-there-a-relation-between-priapism-occurring-after-penile-doppler-ultrasonography-and-international-erectile-function-index-score-and-erection-hardness-score-levels
#20
Mehmet Giray Sönmez, Ahmet Öztürk
Objective: The relation between Erection Hardness Score (EHS) and The International Erectile Function Index (IIEF) Questionnaire- Erectile Function Domain Score (IIEF-EF score) used in erectile dysfunction (ED) evaluation and the prevalence of priapism after penile Doppler ultrasonography (PDU) was examined in this study. Material and methods: A total of 62 patients who had PDU were included in the study. Patients were divided into two groups; there were 33 patients in IIEF-EF score ≤10, EHS <2 group (Group 1) and 29 patients in IIEF-EF score >10, EHS ≥2 group (Group 2)...
December 2017: Turkish Journal of Urology
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