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https://www.readbyqxmd.com/read/29655571/a-rapid-access-chest-pain-clinic-racpc-initial-australian-experience
#1
C Yu, M J Sheriff, A C C Ng, S Brazete, J Gullick, D B Brieger, L Kritharides, H C Lowe
Chest pain is the second most common presenting symptom to emergency departments (ED) in Australia, although up to 85% of these patients do not have an acute coronary syndrome (ACS). Cardiologist-led rapid access chest pain clinics (RACPC) have been proposed overseas to assist in the management of such patients, with prompt outpatient assessment if patients are deemed low risk and discharged from the ED. The use of RACPCs in Australia has been only recently proposed; we therefore sought to examine one such RACPC in an Australian context...
December 11, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29652277/factors-associated-with-delayed-cardiac-tamponade-after-cardiac-surgery
#2
Edgar Hernández Leiva, Marisol Carreño, Fernando Rada Bucheli, Alberto Cadena Bonfanti, Juan Pablo Umaña, Rodolfo José Dennis
Context: Cardiac tamponade (CT) following cardiac surgery is a potentially fatal complication and the cause of surgical reintervention in 0.1%-6% of cases. There are two types of CT: acute, occurring within the first 48 h postoperatively, and subacute or delayed, which occurs more than 48 h postoperatively. The latter does not show specific clinical signs, which makes it more difficult to diagnose. The factors associated with acute CT (aCT) are related to coagulopathy or surgical bleeding, while the variables associated with subacute tamponade have not been well defined...
April 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/29650121/prediction-of-abnormal-myocardial-relaxation-from-signal-processed-surface-ecg
#3
Partho P Sengupta, Hemant Kulkarni, Jagat Narula
BACKGROUND: Myocardial relaxation is impaired in almost all cases with left ventricular diastolic dysfunction (LVDD) and is a strong predictor of cardiovascular and all-cause mortality. OBJECTIVES: This study investigated the feasibility of signal-processed surface electrocardiography (spECG) as a diagnostic tool for predicting the presence of abnormal cardiac muscle relaxation. METHODS: A total of 188 outpatients referred for coronary computed tomography (CT) angiography underwent an echocardiogram for assessment of LVDD...
April 17, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29628189/development-of-a-congenital-cardiovascular-computed-tomography-imaging-registry-rationale-and-implementation
#4
B Kelly Han, Susan Casey, Dawn Witt, Jonathon Leipsic, Andrew Crean, Edward Nicol, Thomas Semple, James Shambrook, Ashwin Prakash, Puja Banka, Ross Garberich, Cynthia Rigsby, Anthony Hlavacek, John Lesser
BACKGROUND: The cumulative exposure and risk of anesthesia, vascular access, contrast agents and radiation is emerging as a significant lifelong burden in patients with congenital heart disease (CHD). Latest generation computerized tomographic (CT) scanners are increasingly used for high resolution cardiovascular imaging and have both hardware and post processing radiation dose reduction strategies that can be implemented. Currently, these dose reduction strategies are not uniformly applied and there is a large variability in radiation dose used for the performance of CT in CHD...
March 16, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29626939/the-3m-approach-to-cardiovascular-infections-multimodality-multitracers-and-multidisciplinary
#5
REVIEW
Martina Sollini, Raffaella Berchiolli, Roberto C Delgado Bolton, Alexia Rossi, Margarita Kirienko, Roberto Boni, Elena Lazzeri, Riemer Slart, Paola Anna Erba
Cardiovascular infections are associated with high morbidity and mortality. Early diagnosis is crucial for adequate patient management, as early treatment improves the prognosis. The diagnosis cannot be made on the basis of a single symptom, sign, or diagnostic test. Rather, the diagnosis requires a multidisciplinary discussion in addition to the integration of clinical signs, microbiology data, and imaging data. The application of multimodality imaging, including molecular imaging techniques, has improved the sensitivity to detect infections involving heart valves and vessels and implanted cardiovascular devices while also allowing for early detection of septic emboli and metastatic infections before these become clinically apparent...
May 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29623849/cardiac-imaging-in-systemic-diseases-what-the-clinician-should-know
#6
Cesar J Herrera, Pamela Pina Santana, Jorge Martinez, Mario J Garcia
IMPORTANCE: Systemic diseases that affect the cardiovascular system constitute a diagnostic and therapeutic challenge for all specialists involved; imaging tools along with clinical suspicion play an essential role in their evaluation. These entities share neurological, immunological, renal, hematologic, oncologic, infectious and endocrine processes, all of which may have associated cardiac involvement. OBSERVATIONS: Recent advances in cardiac ultrasound, computed tomography (CT), cardiac magnetic resonance (CMR) and nuclear scintigraphy have impacted the management of these conditions when involving the heart since they provide valuable anatomical and functional information while avoiding the use of invasive techniques...
April 5, 2018: Current Cardiology Reviews
https://www.readbyqxmd.com/read/29622992/the-degree-of-hair-graying-as-an-independent-risk-marker-for-coronary-artery-disease-a-ct-coronary-angiography-study
#7
Amr Abdel Aziz ElFaramawy, Irini Samuel Hanna, Reham Mohamed Darweesh, Ahmed Shehata Ismail, Hossam Ibrahim Kandil
Background: Cardiovascular disease is a leading cause of death worldwide. Aging is an unavoidable coronary risk factor and is associated with dermatological signs that could be a marker for increased coronary risk. We tested the hypothesis that hair graying as a visible marker of aging is associated with risk of coronary artery disease (CAD) independent of chronological age. Methods: This cross-sectional study included 545 males who underwent a computed tomography coronary angiography (CTCA) for suspicious of CAD, patients were divided into subgroups according to the percentage of gray/white hairs (Hair Whitening Score, HWS: 1-5) and to the absence or presence of CAD...
March 2018: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29619516/hippocampal-calcification-on-brain-ct-prevalence-and-risk-factors-in-a-cerebrovascular-cohort
#8
Remko Kockelkoren, Jill B De Vis, M Stavenga, Willem P Th M Mali, Jeroen Hendrikse, Annemieke M Rozemuller, Huiberdina L Koek, Irene C van der Schaaf, Birgitta K Velthuis, Pim A de Jong
OBJECTIVES: Recently, hippocampal calcification as observed on brain CT examinations was identified in over 20% of people over 50 years of age and a relation between hippocampal calcification and cognitive decline was shown. We determined the prevalence and investigated the vascular risk factors of hippocampal calcification in patients with cerebrovascular disease. METHODS: Hippocampal calcification was scored bilaterally on presence and severity on CT examinations in a cohort of 1130 patients with (suspected) acute ischaemic stroke...
April 4, 2018: European Radiology
https://www.readbyqxmd.com/read/29614023/genomic-influence-in-the-prevention-of-cardiovascular-diseases-with-a-sterol-based-treatment
#9
Ismael San Mauro Martín, Javier Andrés Blumenfeld Olivares, Eva Pérez Arruche, Esperanza Arce Delgado, María José Ciudad Cabañas, Elena Garicano Vilar, Luis Collado Yurrita
Raised serum cholesterol concentration is a well-established risk factor in cardiovascular disease. In addition, genetic load may have an indirect influence on cardiovascular risk. Plant-based sterol-supplemented foods are recommended to help reduce the serum low-density lipoprotein cholesterol level. The objective was to analyse the influence of different polymorphisms in hypercholesterolemia patients following a dietary treatment with plant sterols. A randomised double-blind cross-over controlled clinical trial was carried out in 45 people (25 women)...
April 3, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/29607968/the-sglt2-inhibitor-dapagliflozin-significantly-improves-the-peripheral-microvascular-endothelial-function-in-patients-with-uncontrolled-type-2-diabetes-mellitus
#10
Seigo Sugiyama, Hideaki Jinnouchi, Noboru Kurinami, Kunio Hieshima, Akira Yoshida, Katsunori Jinnouchi, Hiroyuki Nishimura, Tomoko Suzuki, Fumio Miyamoto, Keizo Kajiwara, Tomio Jinnouchi
Objective Sodium-glucose cotransporter-2 (SGLT2) inhibitors reduce cardiovascular events and decrease the body fat mass in patients with type 2 diabetes mellitus (T2DM). We examined whether or not the SGLT2-inhibitor dapagliflozin can improve the endothelial function associated with a reduction in abdominal fat mass. Methods We prospectively recruited patients with uncontrolled (hemoglobin A1c [HbA1c] >7.0%) T2DM who were not being treated by SGLT2 inhibitors. Patients were treated with add-on dapagliflozin (5 mg/day) or non-SGLT2 inhibitor medicines for 6 months to improve their HbA1c...
March 30, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29607318/calcitriol-prevents-cardiovascular-repercussions-in-puromycin-aminonucleoside-induced-nephrotic-syndrome
#11
Fernandes-Cerqueira Cátia, Quelhas-Santos Janete, Sampaio-Maia Benedita, Simões-Silva Liliana, Soares-Silva Isabel, Roncon-Albuquerque Roberto, Pestana Manuel
Puromycin aminonucleoside-induced nephrotic syndrome (PAN-NS) is characterized by cardiac remodeling and increased local inflammatory activity. Patients with NS and animal models of NS have vitamin D3 deficiency. The aim of the present study was to evaluate the influence of calcitriol on cardiac remodeling and local inflammatory state in PAN-NS rat model. Male Sprague-Dawley rats were injected with PAN or vehicle on day 0. PAN and control rats were divided into two subgroups for the administration of calcitriol (PAN-D and Ct-D groups) or the vehicle (PAN-V and Ct-V groups) during 21 days...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29600601/pelvic-artery-calcification-score-is-a-marker-of-vascular-calcification-in-male-hemodialysis-patients
#12
Tomohiko Matsuura, Takaya Abe, Mitsutaka Onoda, Daiki Ikarashi, Jun Sugimura, Toshiaki Komaki, Nariyuki Sasaki, Yumiko Takasawa, Tetsuo Kato, Kunihiro Yoshioka, Shigeru Ehara, Wataru Obara
Patients who undergo hemodialysis often suffer from cardiovascular disease (CVD), and evaluation of coronary artery calcification is extremely important. These evaluations are typically conducted using a noninvasive method including electron beam computed tomography (CT) or multi-detector CT, and the Agatston method to calculate the coronary artery calcification score (CACS). However, it is difficult to use for patients undergoing dialysis. Because patients undergoing dialysis is too strong in coronary artery calcification, and results become incorrect...
March 30, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29596289/identification-and-management-of-acute-cardiac-tamponade
#13
Nancy L York, Christy Kane, Carol S Smith
Although incidence is rare, acute cardiac tamponade (CT) is a cardiovascular condition often resulting in a high mortality rate. In acute CT, rapid accumulation of fluid occurs in the pericardial sac and prevents the heart's chambers from adequately filling with blood, leading to reduced diastolic filling, diminished stroke volumes, and subsequent hemodynamic instability. Health care providers should be aware of at-risk patients and the earliest signs and symptoms because an acute CT is considered a medical emergency...
May 2018: Dimensions of Critical Care Nursing: DCCN
https://www.readbyqxmd.com/read/29590197/correlation-between-coronary-artery-calcification-by-non-cardiac-ct-and-framingham-score-in-young-patients
#14
Gabriel Lichtenstein, Amichai Perlman, Shoshana Shpitzen, Ronen Durst, Dorit Shaham, Eran Leitersdorf, Auryan Szalat
BACKGROUND: Previous studies have established a correlation between coronary artery calcification (CAC) measured by ECG-gated chest computed tomography (CT) and cardiovascular disease. Recent reports which included asymptomatic patients suggest that CAC measured on non-ECG gated CT is similarly associated with cardiovascular risk. This study investigates the correlation between the Framingham Risk Score (FRS) and an incidental finding of CAC on a non-gated chest CT performed for non-cardiac indications in young and seemingly healthy adults...
2018: PloS One
https://www.readbyqxmd.com/read/29588066/life-threatening-everolimus-associated-pneumonitis-a-case-report-and-a-review-of-the-literature
#15
F Almeida, S Amorim, A Sarmento, L Santos
INTRODUCTION: Noninfective pneumonitis is a class-related effect within mammalian target of rapamycin (mTOR) inhibitors, including everolimus, and can occasionally be severe. CASE REPORT: A 62-year-old man, medicated with everolimus due to a heart transplantation 17 years previously and with chronic kidney disease, was admitted to the intensive care unit (ICU) with acute respiratory failure, cardiovascular shock, and impaired renal function requiring dialysis. Computed tomography (CT) scan revealed right upper lobe consolidation...
March 24, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29579601/circulating-interleukin-6-is-a-biomarker-for-coronary-atherosclerosis-in-nonalcoholic-fatty-liver-disease-results-from-the-multi-ethnic-study-of-atherosclerosis
#16
Tracey G Simon, Maria Esther Perez Trejo, Robyn McClelland, Ryan Bradley, Michael J Blaha, Irfan Zeb, Kathleen E Corey, Matthew J Budoff, Raymond T Chung
BACKGROUND: Biomarkers to predict the presence and severity of subclinical cardiovascular disease (CVD) in nonalcoholic fatty liver disease (NAFLD) are lacking. METHODS: 3876 participants from the Multi-Ethnic Study of Atherosclerosis (MESA), without known chronic liver disease underwent baseline non-contrast cardiac CT, with NAFLD defined by validated liver:spleen ratio (L:S) < 1.0, and subclinical CVD defined by coronary artery calcium (CAC) score > 0...
May 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29573979/incidentally-detected-atherosclerosis-in-the-abdominal-aorta-or-its-major-branches-on-computed-tomography-is-highly-associated-with-coronary-heart-disease-in-asymptomatic-adults
#17
Beomseok Suh, Yong Sub Song, Dong Wook Shin, Jiyeon Lim, Hyunbin Kim, Sa-Hong Min, Seung-Pyo Lee, Eun-Ah Park, Whal Lee, Hyejin Lee, Jin Ho Park, BeLong Cho
BACKGROUND: Atherosclerotic lesions in the abdominal aorta or its major branches are often incidentally detected on abdominal CT. However, clinical implications and optimal subsequent management are mostly left undetermined. METHODS: Consecutive, asymptomatic adults (age≥30) who underwent both abdominal CT and coronary computed tomography angiography as part of a self-referred health check-up were investigated (n = 1494). RESULTS: Adjusted for cardiovascular risk factors, abdominal atherosclerotic lesions with stenosis<25% were associated with significant coronary stenosis, especially in the abdominal aorta (adjusted odds ratio [aOR] 3...
March 15, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29572879/patient-specific-atrial-hemodynamics-of-a-double-lumen-neonatal-cannula-in-correct-caval-position
#18
Jamil Muhammad, Mohammad Rezaeimoghaddam, Bilgesu Cakmak, Reza Rasooli, Ece Salihoglu, Yahya Yıldız, Kerem Pekkan
Clinical success of pediatric veno-venous (VV) extracorporeal membrane oxygenation (ECMO) is associated with the double lumen cannula cardiovascular device design as well as its anatomic orientation in the atrium. The positions of cannula ports with respect to the vena cavae and the tricuspid valve are believed to play a significant role on device hemodynamics. Despite various improvements in ECMO catheters, especially for the neonatal and congenital heart patients, it is still challenging to select a catalogue size that would fit to most patients optimally...
March 23, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29571781/influence-of-image-reconstruction-parameters-on-cardiovascular-risk-reclassification-by-computed-tomography-coronary-artery-calcium-score
#19
Cesare Mantini, Erica Maffei, Patrizia Toia, Fabrizio Ricci, Sara Seitun, Alberto Clemente, Roberto Malagò, Giuseppe Runza, Ludovico La Grutta, Massimo Midiri, Antonio Raffaele Cotroneo, Ernesto Forte, Filippo Cademartiri
OBJECTIVE: To investigate the influence of different CT reconstruction parameters on coronary artery calcium scoring (CACS) values and reclassification of predicted cardiovascular (CV) risk. METHODS: CACS was evaluated in 113 patients undergoing ECG-gated 64-slice CT. Reference CACS protocol included standard kernel filter (B35f) with slice thickness/increment of 3/1.5 mm, and field-of-view (FOV) of 150-180 mm. Influence of different image reconstruction algorithms (reconstructed slice thickness/increment 2...
April 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29567630/anthracycline-induced-cardiotoxicity-a-multicenter-randomised-trial-comparing-two-strategies-for-guiding-prevention-with-enalapril-the-international-cardiooncology-society-one-trial
#20
Daniela Cardinale, Fabio Ciceri, Roberto Latini, Maria Grazia Franzosi, Maria Teresa Sandri, Maurizio Civelli, GianFranco Cucchi, Elisabetta Menatti, Maurizio Mangiavacchi, Raffaele Cavina, Enrico Barbieri, Stefania Gori, Alessandro Colombo, Giuseppe Curigliano, Michela Salvatici, Antonio Rizzo, Francesco Ghisoni, Alessandra Bianchi, Cristina Falci, Michele Aquilina, Andrea Rocca, Anna Monopoli, Carlo Milandri, Giuseppe Rossetti, Marco Bregni, Marco Sicuro, Alessandra Malossi, Daniele Nassiacos, Claudio Verusio, Monica Giordano, Lidia Staszewsky, Simona Barlera, Enrico B Nicolis, Michela Magnoli, Serge Masson, Carlo M Cipolla
BACKGROUND: Troponin changes over time have been suggested to allow for an early diagnosis of cardiac injury ensuing cancer chemotherapy; cancer patients with troponin elevation may benefit of therapy with enalapril. It is unknown whether a preventive treatment with enalapril may further increase the benefit. METHODS: The International CardioOncology Society-one trial (ICOS-ONE) was a controlled, open-label trial conducted in 21 Italian hospitals. Patients were randomly assigned to two strategies: enalapril in all patients started before chemotherapy (CT; 'prevention' arm), and enalapril started only in patients with an increase in troponin during or after CT ('troponin-triggered' arm)...
May 2018: European Journal of Cancer
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