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Agatston score

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https://www.readbyqxmd.com/read/29145895/comparative-analysis-of-high-sensitivity-cardiac-troponin-i-and-t-for-their-association-with-coronary-computed-tomography-assessed-calcium-scoring-represented-by-the-agatston-score
#1
Jonas Rusnak, Michael Behnes, Thomas Henzler, Nadine Reckord, Nils Vogler, Mathias Meyer, Ursula Hoffmann, Michele Natale, Julia Hoffmann, Sonja Hamed, Kathrin Weidner, Siegfried Lang, Agnibh Mukherji, Holger Haubenreisser, Stefan O Schoenberg, Martin Borggrefe, Thomas Bertsch, Ibrahim Akin
BACKGROUND: This study evaluates the association between high-sensitivity cardiac troponin I (hs-cTnI) and T (hs-cTnT) and coronary calcium concentration (CAC) detected by coronary computed tomography (CCT) and evaluated with the Agatston score in patients with suspected coronary artery disease (CAD). METHODS: Patients undergoing CCT during routine clinical care were enrolled prospectively. CCT was indicated for patients with a low to intermediate pretest probability for CAD...
November 16, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/29132034/impact-of-flow-mediated-dilatation-and-coronary-calcification-in-providing-complementary-information-on-the-severity-of-coronary-artery-disease
#2
Kentaro Arakawa, Mutsuki Ohno, Mutsuo Horii, Tomoaki Ishigami, Kazuo Kimura, Kouichi Tamura
BACKGROUND AND AIMS: Endothelial dysfunction and coronary artery calcification (CAC) may represent two distinct and separate processes in the development of coronary atherosclerosis. However, the interaction between these factors in determining the development of coronary artery disease (CAD) is uncertain. METHODS: Brachial artery flow-mediated dilatation (FMD) was measured by high-resolution ultrasound before coronary angiography, in 156 patients undergoing coronary CT angiography on suspicion of CAD (M/F 100/56, age 67 ± 11yrs)...
November 3, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29079928/calcification-of-coronary-arteries-in-early-rheumatoid-arthritis-prior-to-anti-rheumatic-therapy
#3
Helen V Udachkina, Diana S Novikova, Tatiana V Popkova, Irina G Kirillova, Evgenia I Markelova, Elena L Luchikhina, Galina V Lukina, Valentin E Sinitsyn, Dmitry E Karateev, Eugeniy L Nasonov
Accelerated coronary atherosclerosis is common in patients with rheumatoid arthritis (RA). To examine coronary artery calcification (CAC) frequency and severity, its correlation with traditional risk factors (TRF) of cardiovascular diseases (CVD) and inflammatory markers in patients with early RA prior to anti-rheumatic therapy. RA adult patients (ACR/EULAR criteria, 2010, duration ≤ 12 months, without prior administration of disease-modifying anti-rheumatic drugs, glucocorticoids) underwent 32-row scanning for CAC scoring...
October 27, 2017: Rheumatology International
https://www.readbyqxmd.com/read/29073168/coronary-endothelial-function-is-better-in-healthy-premenopausal-women-than-in-healthy-older-postmenopausal-women-and-men
#4
Lena Mathews, Micaela Iantorno, Michael Schär, Gabriele Bonanno, Gary Gerstenblith, Robert G Weiss, Allison G Hays
BACKGROUND: Premenopausal women have fewer cardiovascular disease (CVD) events than postmenopausal women and age-matched men, but the reasons are not fully understood. Coronary endothelial function (CEF), a barometer of coronary vascular health, promises important insights into age and sex differences in atherosclerotic CVD risk, but has not been well characterized in healthy individuals because of the invasive nature of conventional CEF measurements. Recently developed magnetic resonance imaging (MRI) methods were used to quantify CEF (coronary area and flow changes in response to isometric handgrip exercise (IHE), an endothelial-dependent stressor) to test the hypothesis that healthy women have better CEF compared to men particularly at a younger age...
2017: PloS One
https://www.readbyqxmd.com/read/29045671/association-between-self-rated-health-and-ideal-cardiovascular-health-the-baptist-health-south-florida-employee-study
#5
Oluseye Ogunmoroti, Ovie A Utuama, Joseph A Salami, Javier Valero-Elizondo, Erica S Spatz, Maribeth Rouseff, Don Parris, Sankalp Das, Henry Guzman, Arthur Agatston, Theodore Feldman, Emir Veledar, Wasim Maziak, Khurram Nasir
Background: There is increasing evidence of the role psychosocial factors play as determinants of cardiovascular health (CVH). We examined the association between self-rated health (SRH) and ideal CVH among employees of a large healthcare organization. Methods: Data were collected in 2014 from employees of Baptist Health South Florida during an annual voluntary health risk assessment and wellness fair. SRH was measured using a self-administered questionnaire where responses ranged from poor, fair, good, very good to excellent...
October 17, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28988831/calcification-remodeling-index-assessed-by-cardiac-ct-predicts-severe-coronary-stenosis-in-lesions-with-moderate-to-severe-calcification
#6
Mengmeng Yu, Yuehua Li, Wenbin Li, Zhigang Lu, Meng Wei, Jiayin Zhang
OBJECTIVES: To assess the diagnostic performance of the calcification remodeling index (RI) as assessed by coronary computed tomography angiography (coronary CTA) to predict the presence of severe coronary stenosis in atherosclerotic coronary lesions with moderate to severe calcification. METHODS: Patients who underwent coronary CTA and invasive coronary angiography (ICA) within one month and had moderately to severely calcified lesions as revealed by coronary CTA, were retrospectively included...
September 30, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28986055/gender-differences-in-the-association-of-epicardial-adipose-tissue-and-coronary-artery-calcification-epicheart-study-eat-and-coronary-calcification-by-gender
#7
Jennifer Mancio, Marilia Pinheiro, Wilson Ferreira, Monica Carvalho, Antonio Barros, Nuno Ferreira, Luis Vouga, Vasco Gama Ribeiro, Adelino Leite-Moreira, Ines Falcao-Pires, Nuno Bettencourt
BACKGROUND: The association of epicardial adipose tissue (EAT) and coronary artery calcification (CAC) seems to differ by gender. However, few studies have controlled for body size, and the ideal method for body size indexing has not been explored. OBJECTIVES: To analyse the effect of gender related-body size and-body fat differences on the association of EAT with CAC. METHODS: This was a prospective cohort of 371 severe aortic stenosis patients (77±8...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28982647/multimodality-intracoronary-imaging-with-near-infrared-spectroscopy-and-intravascular-ultrasound-in-asymptomatic-individuals-with-high-calcium-scores
#8
Ryan D Madder, Stacie VanOosterhout, David Klungle, Abbey Mulder, Matthew Elmore, Jeffrey M Decker, David Langholz, Thomas F Boyden, Jessica Parker, James E Muller
BACKGROUND: This study sought to determine the frequency of large lipid-rich plaques (LRP) in the coronary arteries of individuals with high coronary artery calcium scores (CACS) and to determine whether the CACS correlates with coronary lipid burden. METHODS AND RESULTS: Combined near-infrared spectroscopy and intravascular ultrasound was performed in 57 vessels in 20 asymptomatic individuals (90% on statins) with no prior history of coronary artery disease who had a screening CACS ≥300 Agatston units...
October 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28956774/coronary-artery-calcium-distribution-is-an-independent-predictor-of-incident-major-coronary-heart-disease-events-results-from-the-framingham-heart-study
#9
Maros Ferencik, Karol M Pencina, Ting Liu, Khristine Ghemigian, Kristin Baltrusaitis, Joseph M Massaro, Ralph B D'Agostino, Christopher J O'Donnell, Udo Hoffmann
BACKGROUND: The presence and extent of coronary artery calcium (CAC) are associated with increased risk for cardiovascular events. We determined whether information on the distribution of CAC and coronary dominance as detected by cardiac computed tomography were incremental to traditional Agatston score (AS) in predicting incident major coronary heart disease (CHD). METHODS AND RESULTS: We assessed total AS and the presence of CAC per coronary artery, per segment, and coronary dominance by computed tomography in participants from the offspring and third-generation cohorts of the Framingham Heart Study...
October 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28943454/coronary-artery-calcium-quantification-on-first-second-and-third-generation-dual-source-ct-a-comparison-study
#10
Marleen Vonder, Gert Jan Pelgrim, Sèvrin E M Huijsse, Holger Haubenreisser, Mathias Meyer, Peter M A van Ooijen, Matthijs Oudkerk, Thomas Henzler, Rozemarijn Vliegenthart
BACKGROUND: Differences in coronary artery calcium (CAC) quantification of successive CT systems of one vendor could impact results of CAC screening and progression studies. The purpose of this study is to compare CAC quantification between three generations of dual-source computed tomography (DSCT) systems. METHODS: Three DSCT generations were used to repeatedly scan an anthropomorphic chest phantom and three inserts. The first and second insert contained 100 small and nine large calcifications, respectively, to determine detectability, and the Agatston and (calibrated) mass score, respectively...
September 8, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28939047/differential-expression-of-micrornas-in-severely-calcified-carotid-plaques
#11
Hiroyuki Katano, Yusuke Nishikawa, Hiroshi Yamada, Kazuo Yamada, Mitsuhito Mase
BACKGROUND: We investigated whether microRNA (miRNA) alteration is related to the presence of calcification in carotid plaques. METHODS: We classified 10 plaques from carotid endarterectomy patients into high- and low-calcified plaques based on Agatston calcium scores. A microarray analysis for miRNA profiles was performed, with validation by a miRNA quantitative real-time polymerase chain reaction (qRT-PCR). RESULTS: The miRNA microarray identified 697 probes; 657 of them were downregulated...
September 19, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28929356/a-high-abdominal-aortic-calcification-score-on-ct-is-a-risk-factor-for-postoperative-pancreatic-fistula-in-elderly-patients-undergoing-pancreaticoduodenectomy
#12
Nao Kakizawa, Hiroshi Noda, Fumiaki Watanabe, Kosuke Ichida, Koichi Suzuki, Toshiki Rikiyama
BACKGROUND: To evaluate the clinical significance of a CT-based evaluation of abdominal aortic calcification (AAC) in the postoperative outcomes after pancreaticoduodenectomy (PD) in elderly patients. METHODS: Patients 70 years of age and older who were randomly assigned to Group A were compared with those younger than 70 who were assigned to Group B in terms of preoperative and intraoperative variables and postoperative outcomes. We compared the patients with clinically relevant postoperative pancreatic fistula (CR-POPF) (Group C) to those without CR-POPF (Group D), and especially Group A...
September 19, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28923811/coronary-artery-calcium-progression-is-associated-with-cardiovascular-events-among-asymptomatic-individuals-from-the-north-texas-primary-care-practice-based-research-network-nortex-pbrn
#13
Roberto Cardarelli, Alexandria Hall, Wade Rankin
BACKGROUND: Although incidental coronary artery calcium (CAC) has been established as a surrogate measure for atherosclerotic plaque burden, little is known about its progression and the associated risks. This study looks at the association of select cardiovascular risk factors with the progression of CAC over a 2-year period and the relationship between CAC progression and experiencing a composite cardiovascular disease (CVD) event. METHODS: Repeated CAC measurements were obtained for 311 asymptomatic participants aged >44 years, who were recruited from a collaborative network of primary care clinics...
September 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28867681/effect-of-intensive-and-standard-pitavastatin-treatment-with-or-without-eicosapentaenoic-acid-on-progression-of-coronary-artery-calcification-over-12-months%C3%A3-prospective-multicenter-study
#14
Toru Miyoshi, Kunihisa Kohno, Hirohiko Asonuma, Satoru Sakuragi, Makoto Nakahama, Yusuke Kawai, Tadahisa Uesugi, Takefumi Oka, Mitsuru Munemasa, Natsuki Takahashi, Naoki Mukohara, Seiji Habara, Yasushi Koyama, Kazufumi Nakamura, Hiroshi Ito
BACKGROUND: The effect of lipid-lowering agents on progression of coronary artery calcification (CAC) remains unclear. We evaluated the effects of pitavastatin 2 mg/day (PIT2), pitavastatin 4 mg/day (PIT4), and PIT2 combined with eicosapentaenoic acid (PIT2+EPA) on CAC progression.Methods and Results:This prospective multicenter study in Japan included patients with an Agatston score of 1-999, hypercholesterolemia, and no evidence of cardiovascular disease. Patients were allocated into PIT2, PIT4, or PIT2+EPA groups...
September 1, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28862955/sex-differences-in-associations-of-arterial-compliance-with-coronary-artery-plaque-and-calcification-burden
#15
Thais Coutinho, Yeung Yam, Benjamin J W Chow, Girish Dwivedi, João Inácio
BACKGROUND: Coronary artery disease is a leading killer of women. Arterial stiffness predicts myocardial infarction, and postmenopausal women have lower arterial compliance (AC) than men. We hypothesized that lower AC would be associated with greater burden of coronary artery plaque and calcification, and that these associations would be stronger in women than men. METHODS AND RESULTS: We evaluated 3639 consecutive adults without coronary artery disease history who had coronary computed tomography between 2006 and 2014...
August 19, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28860893/calcification-remodeling-index-characterized-by-cardiac-ct-as-a-novel-parameter-to-predict-the-use-of-rotational-atherectomy-for-coronary-intervention-of-lesions-with-moderate-to-severe-calcification
#16
Mengmeng Yu, Yuehua Li, Wenbin Li, Zhigang Lu, Meng Wei, Jiayin Zhang
OBJECTIVE: To assess the feasibility of calcification characterization by coronary computed tomography angiography (CCTA) to predict the use of rotational atherectomy (RA) for coronary intervention of lesions with moderate to severe calcification. MATERIALS AND METHODS: Patients with calcified lesions treated by percutaneous coronary intervention (PCI) who underwent both CCTA and invasive coronary angiography were retrospectively included in this study. Calcification remodeling index was calculated as the ratio of the smallest vessel cross-sectional area of the lesion to the proximal reference luminal area...
September 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28855585/nonalcoholic-fatty-liver-disease-and-coronary-artery-calcification-in-a-northern-chinese-population-a-cross-sectional-study
#17
Rina Wu, Feng Hou, Xiaomin Wang, Yong Zhou, Kai Sun, Youxin Wang, Henghui Liu, Jing Wu, Ruiping Zhao, Jiang Hu
Nonalcoholic fatty liver disease (NAFLD) has become an emerging health issue with a high prevalence in general population. The cross-sectional study was performed to investigate the association between NAFLD and coronary artery calcification (CAC) in individuals from northern city of China. A total of 2345 participants aged ≥40 (1035 men and 1310 women) were selected from the Jidong community of Tangshan city. Liver ultrasonography was used to the diagnosis of NAFLD. A 64-slice CT scanner was used to determine coronary artery calcification score (CACS), with CACS > 0 defined to be the presence of CAC...
August 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28830786/relation-between-serum-levels-of-chemotaxis-related-factors-and-the-presence-of-coronary-artery-calcification-as-expression-of-subclinical-atherosclerosis
#18
Juan Carlos Muñoz, Rubén Martín, Carmen Alonso, Beatriz Gutiérrez, María Luisa Nieto
BACKGROUND: Atherosclerotic plaque formation is characterized by recruitment of monocytes/macrophages, which contributes to its calcification by releasing pro-osteogenic cytokines. Chemotaxis-related proteins, including netrin-1, gremlin-1 and macrophage inflammatory protein-1β (MIP-1β), regulate immune cell migration. However, their relation with the presence of subclinical atherosclerosis, assessed by measures of coronary artery calcifications (CAC) in patients without known coronary artery disease (CAD), remains unclear...
August 19, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28830471/relationship-between-the-triglyceride-glucose-index-and-coronary-artery-calcification-in-korean-adults
#19
Min Kyung Kim, Chul Woo Ahn, Shinae Kang, Ji Sun Nam, Kyung Rae Kim, Jong Suk Park
BACKGROUND: The triglyceride glucose (TyG) index has been considered a simple surrogate marker of insulin resistance. However, few studies have investigated the relationship between the TyG index and coronary artery calcification (CAC). Thus, we investigated the relationship between the TyG index and CAC in healthy Korean adults. METHODS: In total, 4319 participants who underwent cardiac computed tomography (CT) in a health promotion center were enrolled. Anthropometric profiles and multiple cardiovascular risk factors were measured...
August 23, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28815291/prognostic-value-of-atherosclerotic-burden-and-coronary-vascular-function-in-patients-with-suspected-coronary-artery-disease
#20
Roberta Assante, Wanda Acampa, Emilia Zampella, Parthiban Arumugam, Carmela Nappi, Valeria Gaudieri, Ciro Gabriele Mainolfi, Mariarosaria Panico, Mario Magliulo, Christine M Tonge, Mario Petretta, Alberto Cuocolo
PURPOSE: To evaluate the prognostic value of coronary atherosclerotic burden, assessed by coronary artery calcium (CAC) score, and coronary vascular function, assessed by coronary flow reserve (CFR) in patients with suspected coronary artery disease (CAD). METHODS: We studied 436 patients undergoing hybrid (82)Rb positron emission tomography/computed tomography imaging. CAC score was measured according to the Agatston method, and patients were categorized into three groups (0, <400, and ≥400)...
December 2017: European Journal of Nuclear Medicine and Molecular Imaging
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