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Agatston score

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https://www.readbyqxmd.com/read/28523594/the-relationship-between-coronary-artery-calcium-scores-and-left-atrium-size-in-hemodialysis-patients
#1
Ismail Baloglu, Kultigin Turkmen, H Zeki Tonbul, N Yılmaz Selcuk
PURPOSE: Hemodialysis patients have extremely increased cardiovascular mortality. The coronary artery calcification score (CACS) in uremic patients receiving hemodialysis reflects the severity of atherosclerotic vascular disease and predicts the cardiovascular events. In cardiac conditions, left atrial (LA) size has a prognostic importance. In this study, relationship between coronary artery calcification and left atrial size was investigated. METHODS: This was a cross-sectional study involving 32 hemodialysis patients (16 females, 16 males; mean age, 52...
May 18, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28487318/impact-of-coronary-calcification-on-clinical-management-in-patients-with-acute-chest-pain
#2
Daniel O Bittner, Thomas Mayrhofer, Fabian Bamberg, Travis R Hallett, Sumbal Janjua, Daniel Addison, John T Nagurney, James E Udelson, Michael T Lu, Quynh A Truong, Pamela K Woodard, Judd E Hollander, Chadwick Miller, Anna Marie Chang, Harjit Singh, Harold Litt, Udo Hoffmann, Maros Ferencik
BACKGROUND: Coronary artery calcification (CAC) may impair diagnostic assessment of coronary computed tomography angiography (CTA). We determined whether CAC affects efficiency of coronary CTA in patients with suspected acute coronary syndrome (ACS). METHODS AND RESULTS: This is a pooled analysis of ACRIN-PA (American College of Radiology Imaging Network-Pennsylvania) 4005 and the ROMICAT-II trial (Rule Out Myocardial Infarction/Ischemia Using Computer Assisted Tomography) comparing an initial coronary CTA strategy to standard of care in acute chest pain patients...
May 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28483581/prognostic-value-of-segment-involvement-score-compared-to-other-measures-of-coronary-atherosclerosis-by-computed-tomography-a-systematic-review-and-meta-analysis
#3
Chadi Ayoub, Fernanda Erthal, Mahmoud A Abdelsalam, M Hassan Murad, Zhen Wang, Patricia J Erwin, Graham S Hillis, Leonard Kritharides, Benjamin J W Chow
BACKGROUND: The segment involvement score (SIS) is a semiquantitative measure of the extent of atherosclerosis burden by coronary computed tomography angiography (CTA). We sought to evaluate by meta-analysis the prognostic value of SIS, and to compare it with other CTA measures of coronary artery disease (CAD). METHODS: Electronic databases from 1946 to January 2016 were searched. Studies reporting SIS, or an equivalent measure by coronary CTA, and clinical outcomes were included...
May 3, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28473443/relationship-of-autoantibodies-to-mda-ldl-and-apob-immune-complexes-to-sex-ethnicity-subclinical-atherosclerosis-and-cardiovascular-events
#4
Anand Prasad, Paul Clopton, Colby Ayers, Amit Khera, James A de Lemos, Joseph L Witztum, Sotirios Tsimikas
OBJECTIVE: Modifications of lipid constituents within atherosclerotic lesions generate neoepitopes that activate innate and adaptive immune responses. We aimed to define the prevalence, distribution, and relationship of autoantibody titers of oxidized lipoproteins to subclinical atherosclerosis and major adverse cardiovascular events (MACE) in different ethnic groups. APPROACH AND RESULTS: IgG and IgM autoantibodies to malondialdehyde-modified low-density lipoprotein (MDA-LDL) and apolipoprotein B-100-immune complexes were measured in 3509 individuals (1814 blacks, 1031 whites, 589 Hispanics, and 85 no race identifier) from the Dallas Heart Study with median 10...
May 4, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28453572/assessment-of-coronary-artery-calcium-by-chest-ct-compared-with-ekg-gated-cardiac-ct-in-the-multicenter-aids-cohort-study
#5
Divay Chandra, Aman Gupta, Joseph K Leader, Meghan Fitzpatrick, Lawrence A Kingsley, Eric Kleerup, Sabina A Haberlen, Matthew J Budoff, Mallory Witt, Wendy S Post, Frank C Sciurba, Alison Morris
RATIONALE: Individuals with HIV are at increased risk for coronary artery disease (CAD). Early detection of subclinical CAD by assessment of coronary artery calcium (CAC) may help risk stratify and prevent CAD events in these individuals. However, the current standard to quantify CAC i.e. Agatston scoring requires EKG-gated cardiac CT imaging. OBJECTIVE: To determine if the assessment of CAC using non-EKG-gated chest CT and the Weston scoring system is a useful surrogate for Agatston scores in HIV-infected and HIV-uninfected individuals...
2017: PloS One
https://www.readbyqxmd.com/read/28449836/aortic-calcification-progression-in-heterozygote-familial-hypercholesterolemia
#6
Manal Al Kindi, Alexandre M Bélanger, Karl Sayegh, Soumia Senouci, Sumayah Aljenedil, Lojan Sivakumaran, Isabelle Ruel, Khalid Al Rasadi, Khalid Al Waili, Zuhier Awan, David Valenti, Jacques Genest
BACKGROUND: Patients with homozygous and heterozygous familial hypercholesterolemia (HeFH) develop severe aortic calcifications in an age- and gene dosage-dependent manner. The purpose of this study was to determine the rate of progression of aortic calcification in patients with HeFH. METHODS: We performed thoracoabdominal computed tomography scans and quantified aortic calcium (AoCa) score in 16 HeFH patients, all with the null low-density lipoprotein (LDL) receptor DEL15Kb mutation...
May 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28449466/higher-coronary-artery-calcification-score-is-associated-with-adverse-prognosis-in-patients-with-stable-angina-pectoris
#7
Renrong Wang, Xiaoxiao Liu, Chunxia Wang, Xinhe Ye, Xin Xu, Chengjian Yang
BACKGROUND: Coronary artery calcification (CAC) indicates the presence of atherosclerotic lesions and serves as a marker of prognosis in patients with coronary artery disease (CAD). This study evaluated the value of the CAC score for determining the prognosis of patients with stable angina pectoris (SAP). METHODS: A total of 106 consecutive patients with SAP were enrolled in this study from January 2011 to June 2014; from these patients, 640 multi-slice computer tomography (MSCT) samples were used to obtain CAC scores...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28437443/relative-predictive-value-of-lung-cancer-screening-ct-versus-myocardial-perfusion-attenuation-correction-ct-in-the-evaluation-of-coronary-calcium
#8
Grant Bailey, Abigail Healy, Bryan D Young, Esseim Sharma, Judith Meadows, Hyung J Chun, Wen-Chih Wu, Gaurav Choudhary, Alan R Morrison
Coronary artery calcium scores (CACS) from lung cancer screening computed tomography (LCSCT) or myocardial perfusion attenuation correction computed tomography (ACCT) are not routinely performed or reported. CACS from LCSCT and ACCT have not been directly compared in the same patient population. We identified 66 patients who underwent both LCSCT (non-gated) and ECG-gated cardiac CT (CCT) within a 2-year span. Of this population, 40 subjects had also undergone ACCT. Using the Agatston method, CACS for 264 individual vessels from the LCSCT population and for 160 vessels from ACCT population were calculated and evaluated for agreement with ECG-gated CCT as the gold standard...
2017: PloS One
https://www.readbyqxmd.com/read/28427294/increased-phagocytic-nadph-oxidase-activity-associates-with-coronary-artery-calcification-in-asymptomatic-men
#9
Oscar Beloqui, María U Moreno, Gorka San José, Álvaro Pejenaute, Adriana Cortés, Manuel F Landecho, Javier Díez, Ana Fortuño, Guillermo Zalba
Vascular calcification is a common feature in atherosclerosis and associates with cardiovascular events. Oxidative stress may be involved in the pathogenesis of vascular calcification. Previous studies have shown that the phagocytic NADPH oxidase is associated with atherosclerosis. The objective of the present study was to investigate the association between phagocytic NADPH oxidase-mediated superoxide production and coronary artery calcium (CAC). NADPH oxidase-mediated superoxide production was determined by chemiluminescence and CAC by computed tomography in 159 asymptomatic men free of overt clinical atherosclerosis...
May 9, 2017: Free Radical Research
https://www.readbyqxmd.com/read/28420590/volume-and-dimensions-of-angiographically-normal-coronary-arteries-assessed-by-multidetector-computed-tomography
#10
Samuel Kiil Sørensen, Jørgen Tobias Kühl, Andreas Fuchs, Jakob Boesgaard Norsk, Lars Valeur Køber, Børge Grønne Nordestgaard, Klaus Fuglsang Kofoed
BACKGROUND: The objective of this study was to determine normal values for coronary artery volume (CAV) and individual vasculature and segment dimensions. METHODS: We examined 200 healthy volunteers with an Agatston score of 0 and a normal, high quality coronary CTA. Using 320 slice multidetector row CT and designated vessel tracing software with border detection algorithm, the main coronary arteries and branches were delineated and total and segmental dimensions calculated...
April 4, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28413071/performance-of-ultra-low-dose-ct-for-the-evaluation-of-coronary-calcification-a-direct-comparison-with-coronary-calcium-score
#11
V V Silveira de Souza, F Soares Torres, B Hochhegger, G Watte, G Sartori, F Lucchese, B Azambuja Gonçalves
AIM: To evaluate the diagnostic performance of ultra-low-dose computed tomography (ULDCT) in comparison to standard coronary calcium score (CCS) acquisition for the evaluation of coronary artery calcification (CAC). MATERIALS AND METHODS: Standard CCS acquisition and ULDCT were performed in patients referred for coronary CT angiography for the evaluation of coronary artery disease. CAC in ULDCT was graded subjectively using a four-point scale (from 0, no calcification, to 3, severe calcification) for the complete study and for each individual coronary segment...
April 13, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28411031/prognostic-value-of-visually-detected-coronary-artery-calcification-on-unenhanced-non-gated-thoracic-computed-tomography-for-prediction-of-non-fatal-myocardial-infarction-and-all-cause-mortality
#12
Lisa Shao, Andrew T Yan, Gerald Lebovic, Harvey H Wong, Anish Kirpalani, Djeven P Deva
PURPOSE: To determine the prognostic value of visually detected coronary artery calcification (CAC) on unenhanced non-gated thoracic computed tomography (CT) for non-fatal myocardial infarction (MI) and all-cause mortality. METHODS: This retrospective single-centre cohort study comprised of 410 consecutive patients aged 40-80 years without any known cardiovascular disease at baseline. CT images without electrocardiogram-gating were acquired for a variety of respiratory medicine indications...
March 28, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28395916/strengths-and-limitations-of-coronary-angiography-with-turbo-high-pitch-third-generation-dual-source-ct
#13
M M Ochs, F Andre, G Korosoglou, T Fritz, S Seitz, Y Bogomazov, C L Schlett, R Sokiranski, A Sommer, F Gückel, M Brado, H-U Kauczor, J Görich, H A Katus, S J Buss
AIM: To define practical limitations of diagnostic image quality for recently introduced turbo high-pitch scan mode (THP) in third-generation dual-source computed tomography (CT). MATERIALS AND METHODS: Two hundred and twenty-nine consecutive patients undergoing CT coronary angiography were included in this retrospective single-centre analysis. A contrast-enhanced volume dataset was acquired in THP. Image quality of coronary segments was classified as diagnostic or non-diagnostic by three blinded readers...
April 8, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28392544/impact-of-renal-functional-morphological-dynamics-on-the-calcification-of-coronary-and-abdominal-arteries-in-patients-with-chronic-kidney-disease
#14
Takeo Ichii, Ryota Morimoto, Takahiro Okumura, Hideki Ishii, Yosuke Tatami, Dai Yamamoto, Soichiro Aoki, Hiroaki Hiraiwa, Kenji Furusawa, Toru Kondo, Naoki Watanabe, Naoaki Kano, Kenji Fukaya, Akinori Sawamura, Susumu Suzuki, Yoshinari Yasuda, Toyoaki Murohara
AIM: Fast-progressing vascular calcification (VC) is accompanied by renal atrophy and functional deterioration along with atherosclerosis in patients with chronic kidney disease (CKD). However, the relationship between VC progression and renal functional and/or morphological changes remains unclear. METHODS: We included 70 asymptomatic patients with CKD without hemodialysis in our study. To identify temporal variations, the coronary artery calcification score (CACS), abdominal aortic calcification index (ACI), and renal parenchymal volume index (RPVI) were determined via spiral computed tomography scans taken during the study...
April 8, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28388944/renal-function-had-an-independent-relationship-with-coronary-artery-calcification-in-chinese-elderly-men
#15
Shihui Fu, Zhao Zhang, Leiming Luo, Ping Ye
BACKGROUND: Although previous studies have analyzed the relationship between renal function and coronary artery calcification (CAC) in pre-dialysis and dialysis patients, limited studies have discussed the relationship between renal function and CAC in Chinese elderly men without obvious damage of renal function. The present study was designed to explore the relationship between renal function and CAC in Chinese elderly men without obvious damage of renal function. METHODS: This cross-sectional study was carried out in 105 male participants older than 60 years with glomerular filtration rate (GFR) ≥ 45 ml/min/1...
April 7, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28378112/automatic-determination-of-cardiovascular-risk-by-ct-attenuation-correction-maps-in-rb-82-pet-ct
#16
Ivana Išgum, Bob D de Vos, Jelmer M Wolterink, Damini Dey, Daniel S Berman, Mathieu Rubeaux, Tim Leiner, Piotr J Slomka
BACKGROUND: We investigated fully automatic coronary artery calcium (CAC) scoring and cardiovascular disease (CVD) risk categorization from CT attenuation correction (CTAC) acquired at rest and stress during cardiac PET/CT and compared it with manual annotations in CTAC and with dedicated calcium scoring CT (CSCT). METHODS AND RESULTS: We included 133 consecutive patients undergoing myocardial perfusion (82)Rb PET/CT with the acquisition of low-dose CTAC at rest and stress...
April 4, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28369281/relation-between-calcium-burden-echocardiographic-stent-frame-eccentricity-and-paravalvular-leakage-after-corevalve-transcatheter-aortic-valve-implantation
#17
Luigi F M Di Martino, Osama I I Soliman, Lennart van Gils, Wim B Vletter, Nicolas M Van Mieghem, Ben Ren, Tjebbe W Galema, Carl Schultz, Peter P T de Jaegere, Matteo Di Biase, Marcel L Geleijnse
Aims: Paravalvular aortic leakage (PVL) after transcatheter aortic valve implantation (TAVI) is a complication with potentially severe consequences. The relation between native aortic root calcium burden, stent frame eccentricity and PVL was not studied before. Methods and results: Two-hundred-and-twenty-three consecutive patients with severe aortic stenosis who underwent TAVI with a Medtronic CoreValve System© and who had available pre-discharge transthoracic echocardiography were studied...
March 27, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28361742/coffee-consumption-and-calcified-atherosclerotic-plaques-in-the-coronary-arteries-the-nhlbi-family-heart-study
#18
Yash R Patel, Taraka V Gadiraju, R Curtis Ellison, Steven C Hunt, John Jeffrey Carr, Gerardo Heiss, Donna K Arnett, James S Pankow, J Michael Gaziano, Luc Djoussé
BACKGROUND & AIMS: While a recent meta-analysis of prospective studies reported that coffee consumption is associated with a lower risk of cardiovascular disease mortality, limited and inconsistent data are available on the relation of coffee intake with subclinical disease. Thus, the aim of the present study was to see the association of coffee consumption with the prevalence of atherosclerotic plaque in the coronary arteries in NHLBI Family Heart Study. METHODS: In a cross-sectional design, we studied 1929 participants of the NHLBI Family Heart Study without known coronary heart disease...
February 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28349280/quantification-of-temporal-changes-in-calcium-score-in-active-atherosclerotic-plaque-in-major-vessels-by-18-f-sodium-fluoride-pet-ct
#19
Yoshinobu Ishiwata, Tomohiro Kaneta, Shintaro Nawata, Ayako Hino-Shishikura, Keisuke Yoshida, Tomio Inoue
PURPOSE: Our aim was to assess whether (18)F-NaF PET/CT is able to predict progression of the CT calcium score. METHODS: Between August 2007 and November 2015, 34 patients (18 women, 16 men; age, mean ± standard deviation, 57.5 ± 13.9 years; age range 19-78 years) with malignancy or orthopaedic disease were enrolled in this study, with approximately 1-year follow-up data. Baseline and follow-up CT images were retrospectively evaluated for the presence of calcification sites in major vessel walls...
March 27, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28324126/relationship-between-cardiac-calcification-and-left-ventricular-hypertrophy-in-patients-with-chronic-kidney-disease-at-hemodialysis-initiation
#20
Ken Kitamura, Hideki Fujii, Kentaro Nakai, Keiji Kono, Shunsuke Goto, Tatsuya Nishii, Atsushi Kono, Shinichi Nishi
Coronary artery calcification (CAC), cardiac valve calcification (CVC) and left ventricular hypertrophy (LVH) are frequently observed in chronic kidney disease (CKD) patients. These abnormalities significantly affect morbidity and mortality. The aim of this study was to investigate the relationship between CAC, CVC and LVH in CKD patients. This study included 96 patients who were hospitalized and initiated hemodialysis between December 2011 and July 2014 at our five institutions. Multi-detector computed tomography for the quantification of CAC using the Agatston score and transthoracic echocardiography for assessing CVC and LVH were performed for all patients included in the study...
March 21, 2017: Heart and Vessels
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