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Agatston score

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https://www.readbyqxmd.com/read/29785308/the-correlation-of-dyslipidemia-with-the-extent-of-coronary-artery-disease-in-the-multiethnic-study-of-atherosclerosis
#1
Moshrik Abd Alamir, Michael Goyfman, Adib Chaus, Firas Dabbous, Leslie Tamura, Veit Sandfort, Alan Brown, Mathew Budoff
Background: The extent of coronary artery calcium (CAC) improves cardiovascular disease (CVD) risk prediction. The association between common dyslipidemias (combined hyperlipidemia, simple hypercholesterolemia, metabolic Syndrome (MetS), isolated low high-density lipoprotein cholesterol, and isolated hypertriglyceridemia) compared with normolipidemia and the risk of multivessel CAC is underinvestigated. Objectives: To determine whether there is an association between common dyslipidemias compared with normolipidemia, and the extent of coronary artery involvement among MESA participants who were free of clinical cardiovascular disease at baseline...
2018: Journal of Lipids
https://www.readbyqxmd.com/read/29768322/lung-cancer-screening-ct-based-coronary-artery-calcification-in-predicting-cardiovascular-events-a-systematic-review-and-meta-analysis
#2
Lili Fan, Kaikai Fan
BACKGROUND: Coronary artery calcificition (CAC) is a well-established predictor of cardiovascular events (CVEs). We aimed to evaluate whether lung cancer screening computed tomography (CT)-based CAC score has a good cost-effectiveness for predicting CVEs in heavy smokers. METHODS: A literature search was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Pubmed, EMBASE, and Cochrane library databases were systematically searched for relevant studies that investigated the association between lung cancer screening CT-based CAC and CVEs up to December 31, 2017...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29751802/associations-of-coronary-artery-calcified-plaque-density-with-mortality-in-type-2-diabetes-the-diabetes-heart-study
#3
Laura M Raffield, Amanda J Cox, Michael H Criqui, Fang-Chi Hsu, James G Terry, Jianzhao Xu, Barry I Freedman, J Jeffrey Carr, Donald W Bowden
BACKGROUND: Coronary artery calcified plaque (CAC) is strongly predictive of cardiovascular disease (CVD) events and mortality, both in general populations and individuals with type 2 diabetes at high risk for CVD. CAC is typically reported as an Agatston score, which is weighted for increased plaque density. However, the role of CAC density in CVD risk prediction, independently and with CAC volume, remains unclear. METHODS: We examined the role of CAC density in individuals with type 2 diabetes from the family-based Diabetes Heart Study and the African American-Diabetes Heart Study...
May 11, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29748857/dynamic-of-changes-in-coronary-artery-calcification-in-early-rheumatoid-arthritis-patients-over-18-months
#4
Helen V Udachkina, Diana S Novikova, Tatiana V Popkova, Irina G Kirillova, Evgenia I Markelova
The coronary artery calcification (CAC) progression may be useful noninvasive predictor of future cardiovascular events (CVE). The progression rate of CAC in patients with early rheumatoid arthritis (RA) is poorly understood. To assess the dynamic of CAC scores in early RA patients for 18 months, 74 RA adult patients (ACR/EULAR criteria, 2010, duration ≤ 12 months, with moderate/high RA activity, without prior administration of disease-modifying anti-rheumatic drugs or glucocorticoids) were enrolled within the framework of the observational study: women 73%, median age 56 years, median RA duration 6 months, median DAS28[ESR] 5...
May 11, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29725832/coronary-artery-calcium-assessed-with-calibrated-mass-scoring-in-asymptomatic-individuals-results-from-the-copenhagen-general-population-study
#5
Andreas D Knudsen, Andreas Fuchs, J Tobias Kühl, Ben A Arnold, Børge G Nordestgaard, Lars V Køber, Klaus F Kofoed
BACKGROUND: Coronary artery calcification (CAC) is commonly assessed with Agatston score (AS). A higher sensitivity and precision for the detection of CAC has been demonstrated with calibrated mass score (cMS). We hypothesized that cMS would detect low-level CAC not detectable with AS in a large asymptomatic background population. METHODS: Participants (N = 2985) from the Copenhagen General Population Study were evaluated for CAC using both conventional AS and cMS...
May 3, 2018: European Radiology
https://www.readbyqxmd.com/read/29706182/prognostic-impact-of-calcium-score-after-transcatheter-aortic-valve-implantation-performed-with-new-generation-prosthesis
#6
Mariama Akodad, Benoit Lattuca, Audrey Agullo, Jean-Christophe Macia, Thomas Gandet, Grégory Marin, Anaïs Iemmi, Hélène Vernhet, Laurent Schmutz, Nicolas Nagot, Bernard Albat, Guillaume Cayla, Florence Leclercq
Calcium score (CS) is a well-known prognostic factor after transcatheter aortic valve implantation (TAVI) performed with first generation prosthesis but few data are available concerning new generation valves. The aim of this study was to evaluate if CS remains a prognostic factor after Sapien 3 and Evolut R valves implantation. Agatston CS was evaluated on multislice computed tomography before TAVI in 346 patients implanted with Sapien XT (n = 61), CoreValve (n = 57) devices, (group 1, n = 118), and with new generation Sapien 3 (n = 147), Evolut R (n = 81) prosthesis, (group 2, n = 228)...
May 15, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29704026/the-relation-of-low-levels-of-bone-mineral-density-with-coronary-artery-calcium-and-mortality
#7
N Ahmadi, S S Mao, F Hajsadeghi, B Arnold, S Kiramijyan, Y Gao, F Flores, S Azen, M Budoff
Osteoporosis and atherosclerosis are two prevalent major healthcare concerns that frequently coexist. The clinical outcome of 5590 consecutive subjects who underwent coronary artery calcium (CAC) scanning and thoracic bone mineral density (BMD) measurement was assessed. A significant link between low BMD levels and CAC with increased risk of mortality in both genders across ethnicities noted. INTRODUCTION: While a relation of CAC with lower levels of BMD reported previously; it is unclear whether low levels of BMD would be an independent risk factor for CAC and mortality...
April 27, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29703635/differences-in-the-association-of-total-versus-local-coronary-artery-calcium-with-acute-coronary-syndrome-and-culprit-lesions-in-patients-with-acute-chest-pain-the-coronary-calcium-paradox
#8
Stefan B Puchner, Thomas Mayrhofer, Jakob Park, Michael T Lu, Ting Liu, Pal Maurovich-Horvat, Khristine Ghemigian, Daniel O Bittner, Jerome L Fleg, James E Udelson, Quynh A Truong, Udo Hoffmann, Maros Ferencik
BACKGROUND AND AIMS: Total coronary artery calcium (CAC) burden is associated with an increased cardiovascular risk, while local CAC may represent stable plaques. We determined differences in relationship of total CAC with acute coronary syndrome (ACS) and local CAC with culprit lesions in patients with suspected ACS. METHODS: We performed computed tomography (CT) for CAC and CT angiography to assess the presence of significant stenosis and high-risk plaque (positive remodeling, low CT attenuation, napkin-ring sign, spotty calcium) in 37 patients with ACS and 223 controls...
April 17, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29696430/subtraction-ct-angiography-improves-evaluation-of-significant-coronary-artery-disease-in-patients-with-severe-calcifications-or-stents-the-c-sub-320-multicenter-trial
#9
Andreas Fuchs, J Tobias Kühl, Marcus Y Chen, David Viladés Medel, Xavier Alomar, Sujata M Shanbhag, Steffen Helqvist, Klaus F Kofoed
OBJECTIVES: Diagnostic accuracy of conventional coronary CT angiography (CCTAconv ) may be compromised by blooming artifacts from calcifications or stents. Blooming artifacts may be reduced by subtraction coronary CT angiography (CCTAsub ) in which non-contrast and contrast CT data sets are subtracted digitally. We tested whether CCTAsub in patients with severe coronary calcification or stents reduces the number of false-positive stenosis evaluations compared with CCTAconv . METHODS: In this study, 180 symptomatic patients scheduled for invasive coronary angiography (ICA) were prospectively enrolled and CT scanned (2013-2016) at three international centers...
April 25, 2018: European Radiology
https://www.readbyqxmd.com/read/29688734/assessing-the-relation-of-epicardial-fat-thickness-and-volume-quantified-by-256-slice-computed-tomography-scan-with-coronary-artery-disease-and-cardiovascular-risk-factors
#10
Maryam Mohammadzadeh, Vahid Mohammadzadeh, Madjid Shakiba, Marzieh Motevalli, Azadeh Abedini, Sakineh Kadivar, Pouya Entezari, Ali Mohammadzadeh
BACKGROUND: This study aimed to investigate the association between epicardial adipose tissue (EAT) and coronary artery disease (CAD) as well as cardiovascular risk factors. METHODS: Complete medical records of subjects were reviewed and cardiovascular risk factors were recorded. Epicardial fat volume (EFV) and epicardial fat thickness (EFT) were measured using digital volumetry of acquired images using a 256-slice CT-scanner. Calcium score was measured using Agatston method in non-contrast images...
March 1, 2018: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29677630/resting-heart-rate-and-the-incidence-and-progression-of-valvular-calcium-the-multi-ethnic-study-of-atherosclerosis-mesa
#11
Kojo Amoakwa, Oluwaseun E Fashanu, Martin Tibuakuu, Di Zhao, Eliseo Guallar, Seamus P Whelton, Wesley T O'Neal, Wendy S Post, Matthew J Budoff, Erin D Michos
BACKGROUND AND AIMS: Left-sided valvular calcification is associated with cardiovascular disease (CVD) morbidity and mortality. Resting heart rate (RHR) may influence valvular calcium progression through shear stress. Whether RHR, an established CVD risk factor, is associated with valvular calcium progression is unknown. We assessed whether RHR predicts incidence and progression of mitral annular calcium (MAC) and aortic valve calcium (AVC) in a community-based cohort free of CVD at baseline...
April 6, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29627375/longer-diabetes-duration-reduces-myocardial-blood-flow-in-remote-myocardium-assessed-by-dynamic-myocardial-ct-perfusion
#12
Nobuo Tomizawa, Yusuke Fujino, Masaru Kamitani, Shengpu Chou, Kodai Yamamoto, Shinichi Inoh, Takeshi Nojo, Sunao Nakamura
AIMS: To investigate the relationship of type 2 diabetes duration and myocardial blood flow (MBF) assessed by myocardial CT perfusion. MATERIALS AND METHODS: We prospectively included 140 patients with type 2 diabetes who underwent dynamic myocardial CT perfusion exam. MBF of the remote myocardium was calculated using the deconvolution technique and the Voronoi method. The relationships of MBF and diabetic duration, diabetic complications, conventional risk factors, coronary calcium, and coronary stenosis were assessed by logistic regression analysis...
March 16, 2018: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29616627/lumen-boundaries-extracted-from-coronary-computed-tomography-angiography-on-computed-fractional-flow-reserve-ffrct-validation-with-optical-coherence-tomography
#13
Kenzo Uzu, Hiromasa Otake, Gilwoo Choi, Takayoshi Toba, Hyun Jin Kim, Arjun Rou, Michiel Schaap, Leo Grady, Masahito Kawata, Toshiro Shinke, Charles Anthony Taylor, Ken-Ichi Hirata
AIMS: To evaluate the accuracy of minimal lumen area (MLA) by coronary computed tomography angiography (cCTA) and its impact on fractional flow reserve (FFRCT). METHODS AND RESULTS: Fifty-seven patients (118 lesions, 72 vessels) who underwent cCTA and optical coherence tomography (OCT) were enrolled. OCT and cCTA were co-registered and MLAs were measured with both modalities. FFROCT was calculated using OCT-updated models with cCTA-based lumen geometry replaced by OCT-derived geometry...
April 3, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29600601/pelvic-artery-calcification-score-is-a-marker-of-vascular-calcification-in-male-hemodialysis-patients
#14
Tomohiko Matsuura, Takaya Abe, Mitsutaka Onoda, Daiki Ikarashi, Jun Sugimura, Toshiaki Komaki, Nariyuki Sasaki, Yumiko Takasawa, Tetsuo Kato, Kunihiro Yoshioka, Shigeru Ehara, Wataru Obara
Patients who undergo hemodialysis often suffer from cardiovascular disease (CVD), and evaluation of coronary artery calcification is extremely important. These evaluations are typically conducted using a noninvasive method including electron beam computed tomography (CT) or multi-detector CT, and the Agatston method to calculate the coronary artery calcification score (CACS). However, it is difficult to use for patients undergoing dialysis. Because patients undergoing dialysis is too strong in coronary artery calcification, and results become incorrect...
March 30, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29590197/correlation-between-coronary-artery-calcification-by-non-cardiac-ct-and-framingham-score-in-young-patients
#15
Gabriel Lichtenstein, Amichai Perlman, Shoshana Shpitzen, Ronen Durst, Dorit Shaham, Eran Leitersdorf, Auryan Szalat
BACKGROUND: Previous studies have established a correlation between coronary artery calcification (CAC) measured by ECG-gated chest computed tomography (CT) and cardiovascular disease. Recent reports which included asymptomatic patients suggest that CAC measured on non-ECG gated CT is similarly associated with cardiovascular risk. This study investigates the correlation between the Framingham Risk Score (FRS) and an incidental finding of CAC on a non-gated chest CT performed for non-cardiac indications in young and seemingly healthy adults...
2018: PloS One
https://www.readbyqxmd.com/read/29574458/coffee-consumption-and-coronary-artery-calcium-score-cross-sectional-results-of-elsa-brasil-brazilian-longitudinal-study-of-adult-health
#16
Andreia M Miranda, Josiane Steluti, Alessandra C Goulart, Isabela M Benseñor, Paulo A Lotufo, Dirce M Marchioni
BACKGROUND: Available evidence for the relationship between coffee intake and subclinical atherosclerosis is limited and inconsistent. This study aimed to evaluate the association between coffee consumption and coronary artery calcium (CAC) in ELSA-Brasil (Brazilian Longitudinal Study of Adult Health). METHODS AND RESULTS: This cross-sectional study is based on baseline data from participants of the ELSA-Brasil cohort. Only participants living in São Paulo, Brazil, who underwent a CAC measurement (n=4426) were included...
March 24, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29571781/influence-of-image-reconstruction-parameters-on-cardiovascular-risk-reclassification-by-computed-tomography-coronary-artery-calcium-score
#17
Cesare Mantini, Erica Maffei, Patrizia Toia, Fabrizio Ricci, Sara Seitun, Alberto Clemente, Roberto Malagò, Giuseppe Runza, Ludovico La Grutta, Massimo Midiri, Antonio Raffaele Cotroneo, Ernesto Forte, Filippo Cademartiri
OBJECTIVE: To investigate the influence of different CT reconstruction parameters on coronary artery calcium scoring (CACS) values and reclassification of predicted cardiovascular (CV) risk. METHODS: CACS was evaluated in 113 patients undergoing ECG-gated 64-slice CT. Reference CACS protocol included standard kernel filter (B35f) with slice thickness/increment of 3/1.5 mm, and field-of-view (FOV) of 150-180 mm. Influence of different image reconstruction algorithms (reconstructed slice thickness/increment 2...
April 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29555836/computed-tomography-aortic-valve-calcium-scoring-in-patients-with-aortic-stenosis
#18
Tania Pawade, Marie-Annick Clavel, Christophe Tribouilloy, Julien Dreyfus, Tiffany Mathieu, Lionel Tastet, Cedric Renard, Mesut Gun, William Steven Arthur Jenkins, Laurent Macron, Jacob W Sechrist, Joan M Lacomis, Virginia Nguyen, Laura Galian Gay, Hug Cuéllar Calabria, Ioannis Ntalas, Timothy Robert Graham Cartlidge, Bernard Prendergast, Ronak Rajani, Arturo Evangelista, João L Cavalcante, David E Newby, Philippe Pibarot, David Messika Zeitoun, Marc R Dweck
BACKGROUND: Computed tomography aortic valve calcium scoring (CT-AVC) holds promise for the assessment of patients with aortic stenosis (AS). We sought to establish the clinical utility of CT-AVC in an international multicenter cohort of patients. METHODS AND RESULTS: Patients with AS who underwent ECG-gated CT-AVC within 3 months of echocardiography were entered into an international, multicenter, observational registry. Optimal CT-AVC thresholds for diagnosing severe AS were determined in patients with concordant echocardiographic assessments, before being used to arbitrate disease severity in those with discordant measurements...
March 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29551663/high-pitch-versus-sequential-mode-for-coronary-calcium-in-individuals-with-a-high-heart-rate-potential-for-dose-reduction
#19
Marleen Vonder, Rozemarijn Vliegenthart, Merel A Kaatee, Carlijn M van der Aalst, Peter M A van Ooijen, Geertruida H de Bock, Jan Willem Gratama, Dirkjan Kuijpers, Harry J de Koning, Matthijs Oudkerk
BACKGROUND: To determine the impact of high-pitch spiral acquisition on radiation dose and cardiovascular disease (CVD) risk stratification by coronary artery calcium (CAC) assessment with computed tomography in individuals with a high heart rate. METHODS: Of the ROBINSCA trial, 1990 participants with regular rhythm and heart rates >65 beats per minute (bpm) were included. As reference, 390 participants with regular heart rates ≤65 bpm were used. All participants underwent prospectively electrocardiographically(ECG)-triggered imaging of the coronary arteries using dual source CT at 120 kVp, 80 ref mAs using both high-pitch spiral mode and sequential mode...
March 1, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29545452/asymptomatic-coronary-artery-calcifications-in-men-with-systemic-lupus-erythematosus
#20
Juanita Romero-Díaz, Roberto Iván Acosta-Hernández, Sergio Criales-Vera, Erick Kimura-Hayama, Maricruz Domínguez-Quintana, Rocío Morán-Contla, Carlos Núñez-Alvarez, Pilar Lara-Reyes, Carlos Aguilar-Salinas, Jorge Sánchez-Guerrero
OBJECTIVE: To determine whether the prevalence and extent of asymptomatic coronary artery atherosclerosis are increased in men with systemic lupus erythematosus (SLE) compared with age- and sex-matched controls, and to define the associated risk factors. METHODS: Ninety-five patients with SLE (mean ± SD age, 34.7 ± 10.1 yrs) and 100 control subjects (age 34.8 ± 9.7 yrs) with no history of coronary artery disease were screened for coronary artery calcification using multidetector computed tomography...
May 2018: Journal of Rheumatology
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