Read by QxMD icon Read

Agatston score

Tania Pawade, Marie-Annick Clavel, Christophe Tribouilloy, Julien Dreyfus, Tiffany Mathieu, Lionel Tastet, Cedric Renard, Mesut Gun, William Steven Arthur Jenkins, Laurent Macron, Jacob W Sechrist, Joan M Lacomis, Virginia Nguyen, Laura Galian Gay, Hug Cuéllar Calabria, Ioannis Ntalas, Timothy Robert Graham Cartlidge, Bernard Prendergast, Ronak Rajani, Arturo Evangelista, João L Cavalcante, David E Newby, Philippe Pibarot, David Messika Zeitoun, Marc R Dweck
BACKGROUND: Computed tomography aortic valve calcium scoring (CT-AVC) holds promise for the assessment of patients with aortic stenosis (AS). We sought to establish the clinical utility of CT-AVC in an international multicenter cohort of patients. METHODS AND RESULTS: Patients with AS who underwent ECG-gated CT-AVC within 3 months of echocardiography were entered into an international, multicenter, observational registry. Optimal CT-AVC thresholds for diagnosing severe AS were determined in patients with concordant echocardiographic assessments, before being used to arbitrate disease severity in those with discordant measurements...
March 2018: Circulation. Cardiovascular Imaging
Marleen Vonder, Rozemarijn Vliegenthart, Merel A Kaatee, Carlijn M van der Aalst, Peter M A van Ooijen, Geertruida H de Bock, Jan Willem Gratama, Dirkjan Kuijpers, Harry J de Koning, Matthijs Oudkerk
BACKGROUND: To determine the impact of high-pitch spiral acquisition on radiation dose and cardiovascular disease (CVD) risk stratification by coronary artery calcium (CAC) assessment with computed tomography in individuals with a high heart rate. METHODS: Of the ROBINSCA trial, 1990 participants with regular rhythm and heart rates >65 beats per minute (bpm) were included. As reference, 390 participants with regular heart rates ≤65 bpm were used. All participants underwent prospectively electrocardiographically(ECG)-triggered imaging of the coronary arteries using dual source CT at 120 kVp, 80 ref mAs using both high-pitch spiral mode and sequential mode...
March 1, 2018: Journal of Cardiovascular Computed Tomography
Juanita Romero-Díaz, Roberto Iván Acosta-Hernández, Sergio Criales-Vera, Erick Kimura-Hayama, Maricruz Domínguez-Quintana, Rocío Morán-Contla, Carlos Núñez-Alvarez, Pilar Lara-Reyes, Carlos Aguilar-Salinas, Jorge Sánchez-Guerrero
OBJECTIVE: To determine whether the prevalence and extent of asymptomatic coronary artery atherosclerosis are increased in men with systemic lupus erythematosus (SLE) compared with age- and sex-matched controls, and to define the associated risk factors. METHODS: Ninety-five patients with SLE (mean ± SD age, 34.7 ± 10.1 yrs) and 100 control subjects (age 34.8 ± 9.7 yrs) with no history of coronary artery disease were screened for coronary artery calcification using multidetector computed tomography...
March 15, 2018: Journal of Rheumatology
Philippa Howlett, Jane K Cleal, Huihai Wu, Nikunj Shah, Alex Horton, Nick Curzen, Michael Mahmoudi
Objective: MicroRNAs (miRNAs) may serve as potential biomarkers in a variety of pathologies. The aim of this study was to determine whether miRNAs could serve as blood-based markers of isolated coronary artery calcification (CAC) defined as CAC in the absence of an underlying metabolic abnormality. Methods: 24 age-matched and sex-matched patients who had been referred for elective CT coronary calcium score and angiography as part of investigation for cardiac chest pain were recruited...
2018: Open Heart
Nivethitha Ilangkovan, Christian Backer Mogensen, Hans Mickley, Annmarie Touborg Lassen, Jess Lambrechtsen, Niels Peter Ronnow Sand, Rasmus Albiniussen, Jørgen Byg, Flemming Hald, Mette Hjortdal Grønhøj, Axel Diederichsen
OBJECTIVES: To examine and compare the prevalence of coronary artery calcification (CAC) and the frequency of cardiac events in a background population and a cohort of patients with non-specific chest pain (NSCP) who present to an emergency or cardiology department and are discharged without an obvious reason for their symptom. DESIGN: A double-blinded, prospective, observational cohort study that measures both CT-determined CAC scores and cardiac events after 1 year of follow-up...
March 3, 2018: BMJ Open
Ivo M Wagensveld, Britt M Blokker, Andrea Pezzato, Piotr A Wielopolski, Nomdo S Renken, Jan H von der Thüsen, Gabriel P Krestin, M G Myriam Hunink, J Wolter Oosterhuis, Annick C Weustink
Aims: The autopsy rate worldwide is alarmingly low (0-15%). Mortality statistics are important, and it is, therefore, essential to perform autopsies in a sufficient proportion of deaths. The imaging autopsy, non-invasive, or minimally invasive autopsy (MIA) can be used as an alternative to the conventional autopsy in an attempt to improve postmortem diagnostics by increasing the number of postmortem procedures. The aim of this study was to determine the diagnostic accuracy of postmortem magnetic resonance imaging (MRI), computed tomography (CT), and CT-guided biopsy for the detection of acute and chronic myocardial ischaemia...
February 20, 2018: European Heart Journal Cardiovascular Imaging
Joshua D Bundy, Jing Chen, Wei Yang, Matthew Budoff, Alan S Go, Juan E Grunwald, Radhakrishna R Kallem, Wendy S Post, Muredach P Reilly, Ana C Ricardo, Sylvia E Rosas, Xiaoming Zhang, Jiang He
BACKGROUND AND AIMS: Coronary artery calcification (CAC) is common among patients with chronic kidney disease (CKD) and predicts the risk for cardiovascular disease (CVD). We examined the associations of novel risk factors with CAC progression among patients with CKD. METHODS: Among 1123 CKD patients in the Chronic Renal Insufficiency Cohort (CRIC) Study, CAC was measured in Agatston units at baseline and a follow-up visit using electron beam computed tomography or multidetector computed tomography...
February 10, 2018: Atherosclerosis
Ramshanker Ramanathan, Niels Peter R Sand, Johannes J Sidelmann, Bjarne L Nørgaard, Jørgen B Gram
BACKGROUND: Incidence and prevalence of cardiovascular disease (CVD) differ between sexes, and women experience CVD later than men. Changes in fibrin clot lysability are associated with CVD, and the present study addresses sex differences in fibrin clot lysability in asymptomatic middle-aged individuals and the relation to coronary artery calcification (CAC). METHODS: Participants free of morbidities and medication, N = 163, were randomly chosen from a national registry among citizens, 50 or 60 years of age, and were followed for 5 years...
February 13, 2018: Biology of Sex Differences
Marina Dias-Neto, Emmanuel Neves, Fábio Sousa-Nunes, Tiago Henriques-Coelho, Sérgio Sampaio
BACKGROUND: The main objective of this study was to assess the correlation between three semiquantitative and one computerized method based on Agatston Score (AS), when measuring abdominal aortic calcification (AAC) in abdominal aortic aneurysm (AAA) patients. Secondary aim was to access differences in AAC upon clinical variables, when different methods of calcium scoring are used. METHODS: This was an observational, retrospective, cross-sectional study. A database of AAA patients consecutively submitted to elective repair between 2008 and 2015 was used...
February 8, 2018: Journal of Cardiovascular Surgery
Xiaohong Wu, Li Wang, Jingxin Zhong, Jacky Ko, Lin Shi, Yannie Soo, Thomas Leung, Ka Sing Wong, Jill Abrigo, Xiangyan Chen
PURPOSE: Intracranial artery calcification (IAC) has been demonstrated to be correlated with ischemic stroke, cognitive decline, and other vascular events by accumulating evidences from both Western and Asian populations. The proposed study aimed to investigate its potential mechanisms by evaluating the blood flow velocity and pulsatility index (PI) of cerebral arteries. METHODS: Consecutive ischemic stroke patients admitted to the Prince of Wales Hospital were recruited after excluding those with atrial fibrillation or poor temporal window...
February 9, 2018: Neuroradiology
Georg Apfaltrer, Moritz H Albrecht, U Joseph Schoepf, Taylor M Duguay, Carlo N De Cecco, John W Nance, Domenico De Santis, Paul Apfaltrer, Marwen H Eid, Chelsea D Eason, Zachary M Thompson, Maximilian J Bauer, Akos Varga-Szemes, Brian E Jacobs, Erich Sorantin, Christian Tesche
OBJECTIVES: To investigate diagnostic accuracy and radiation dose of high-pitch CT coronary artery calcium scoring (CACS) with tin filtration (Sn100kVp) versus standard 120kVp high-pitch acquisition. METHODS: 78 patients (58% male, 61.5±9.1 years) were prospectively enrolled. Subjects underwent clinical 120kVp high-pitch CACS using third-generation dual-source CT followed by additional high-pitch Sn100kVp acquisition. Agatston scores, calcium volume scores, Agatston score categories, percentile-based risk categorization and radiation metrics were compared...
February 5, 2018: European Radiology
Nicola Gaibazzi, Guido Pastorini, Andrea Biagi, Francesco Tafuni, Claudia Buffa, Silvia Garibaldi, Francesca Boffetti, Giorgio Benatti
BACKGROUND: Imaging stress tests are not ideally accurate to predict anatomically obstructive CAD, leading to a non-trivial rate of unnecessary iCA. This may depend on the threshold used to indicate iCA, and maybe CTA or, one step earlier, CT calcium score could spare most unnecessary iCA in only mildly positive cSE. We assessed the diagnostic accuracy of contrast stress-echocardiography (cSE) in comparison with invasive coronary angiography (iCA), and CT angiography (CTA) only in case of equivocal tests, to find hints helping reduce falsely positive cSE in the suspicion of coronary artery disease (CAD)...
February 6, 2018: Cardiovascular Ultrasound
Sandeep Hedgire, Vinit Baliyan, Evan J Zucker, Daniel O Bittner, Pedro Staziaki, Richard A P Takx, Jan-Erik Scholtz, Nandini Meyersohn, Udo Hoffmann, Brian Ghoshhajra
Purpose To evaluate the frequency and implications of perivascular fat stranding on coronary computed tomography (CT) angiograms obtained for suspected acute coronary syndrome (ACS). Materials and Methods This retrospective registry study was approved by the institutional review board. The authors reviewed the medical records and images of 1403 consecutive patients (796 men, 607 women; mean age, 52.8 years) who underwent coronary CT angiography at the emergency department from February 2012 to March 2016. Fat attenuation, length and number of circumferential quadrants of the affected segment, and attenuation values in the unaffected epicardial and subcutaneous fat were measured...
February 5, 2018: Radiology
Di Wen, Katelyn Nye, Bo Zhou, Robert C Gilkeson, Amit Gupta, Shiraz Ranim, Spencer Couturier, David L Wilson
We have developed a technique to image coronary calcium, an excellent biomarker for atherosclerotic disease, using low cost, low radiation dual energy (DE) chest radiography, with potential for widespread screening from an already ordered exam. Our dual energy coronary calcium (DECC) processing method included automatic heart silhouette segmentation, sliding organ registration and scatter removal to create a bone-image-like, coronary calcium image with significant reduction in motion artifacts and improved calcium conspicuity compared to standard, clinically available DE processing...
January 11, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
Ya-Chun Tang, Yuan-Chang Liu, Ming-Yi Hsu, Hui-Yu Tsai, Chien-Ming Chen
RATIONALE AND OBJECTIVES: We aimed to evaluate integrated adaptive iterative dose reduction 3D (AIDR 3D) algorithm in automatic tube current modulation (ATCM) for the quantification of coronary artery calcium score (CACS) and cardiac risk stratification. MATERIALS AND METHODS: A thoracic phantom with calcium inserts of known densities was scanned with filtered back projection (FBP) and AIDR 3D algorithms in small- and medium-sized phantoms. Twenty-four patients underwent two consecutive scans of CACS with FBP and AIDR 3D algorithms...
January 26, 2018: Academic Radiology
Lena Mathews, Oluseye Ogunmoroti, Khurram Nasir, Roger S Blumenthal, Ovie A Utuama, Maribeth Rouseff, Sankalp Das, Emir Veledar, Theodore Feldman, Arthur Agatston, Di Zhao, Erin D Michos
BACKGROUND: The cardiovascular effects of stress and other psychological factors may be different between women and men. We assessed whether self-perceived adverse psychological factors were associated with achievement of ideal cardiovascular health (CVH) as measured by the American Heart Association's Life's Simple Seven (LS7) and whether this differed by sex. METHODS: This was a cross-sectional study of employees from a large healthcare organization. The LS7 metrics (smoking, physical activity, diet, body mass index, blood pressure, cholesterol, and glucose) were each scored as ideal (2), intermediate (1), or poor (0)...
January 29, 2018: Journal of Women's Health
Taiki Aoyama, Akira Fukumoto, Kenjiro Shigita, Naoki Asayama, Shinichi Mukai, Shinji Nagata
BACKGROUND: Most studies have focused on evaluating the association between the presence of small bowel vascular lesions (SBVLs) and patients' comorbidities. AIMS: We sought to uncover a more fundamental indicator that may predict the presence of SBVLs by considering atherosclerosis qualitatively and quantitatively. METHODS: We enrolled 79 consecutive patients with obscure gastrointestinal bleeding who had undergone computed tomography (CT) and capsule endoscopy or double-balloon endoscopy from January 2015 to June 2017...
January 25, 2018: Digestive Diseases and Sciences
Bailey DeBarmore, Feng-Chang Lin, Laura A Tuttle, Emily Olsson, Alan Hinderliter, Jeffrey L Klein, Anthony J Viera
Blood pressure (BP) variability is associated with progression to clinical atherosclerosis. The evidence is inconclusive if BP variability predicts cardiovascular outcomes in low-risk populations. The aim of this study was to analyze the association of 24-hour BP variability with coronary artery calcium (CAC) among a group of individuals without coronary artery disease. The Masked Hypertension Study targeted patients with borderline high BP (120-149 mm Hg systolic and/or 80-95 mm Hg diastolic). Ambulatory blood pressure monitoring (ABPM) was performed at two time-points, 8 days apart...
January 25, 2018: Journal of Clinical Hypertension
Matthias Koopmann, Liane Hinrichs, Jan Olligs, Michael Lichtenberg, Lars Eckardt, Dirk Böse, Stefan Möhlenkamp, Johannes Waltenberger, Frank Breuckmann
BACKGROUND: Atrial fibrillation (AF) and coronary artery disease (CAD) may be encountered coincidently in a large portion of patients. However, data on coronary artery calcium burden in such patients are lacking. Thus, we sought to determine the value of cardiac computed tomography (CCT) in patients presenting with new-onset AF associated with an intermediate pretest probability for CAD admitted to a chest pain unit (CPU). METHODS: Calcium scores (CS) of 73 new-onset, symptomatic AF subjects without typical clinical, electrocardiographic, or laboratory signs of acute coronary syndrome (ACS) admitted to our CPU were analyzed...
January 24, 2018: European Journal of Medical Research
Carmela Nappi, Valeria Gaudieri, Wanda Acampa, Parthiban Arumugam, Roberta Assante, Emilia Zampella, Teresa Mannarino, Ciro Gabriele Mainolfi, Massimo Imbriaco, Mario Petretta, Alberto Cuocolo
BACKGROUND: Coronary artery calcium (CAC) can be used to estimate vascular age in adults, providing a convenient transformation of CAC from Agatston units into a year's scale. We investigated the role of coronary vascular age in predicting stress-induced myocardial ischemia in subjects with suspected coronary artery disease (CAD). METHODS: A total of 717 subjects referred to CAC scoring and 82Rb PET/CT stress-rest myocardial perfusion imaging for suspected CAD were studied...
January 22, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"