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erythema nodosum

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https://www.readbyqxmd.com/read/29453869/erythema-nodosum-like-eruption-in-the-setting-of-sorafenib-therapy
#1
Emily L Coleman, Shawn E Cowper, Stacey M Stein, Jonathan S Leventhal
No abstract text is available yet for this article.
February 16, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29453213/the-cat-did-it-erythema-nodosum-and-additional-atypical-presentations-of-bartonella-henselae-infection-in-immunocompetent-hosts
#2
Ami Schattner, Livnat Uliel, Ina Dubin
A healthy patient presented with painful skin lesions on the anterior surface of her legs. Erythema nodosum was diagnosed but all the usual causes were ruled out. The finding of bilateral enlarged axillary lymph nodes with necrosis and granulomas led to the diagnosis of Bartonella infection, an unusual cause of erythema nodosum. Imaging also revealed splenomegaly and small para-aortic lymph nodes. Up to one quarter of the patients with cat-scratch disease present atypically, a considerably higher prevalence than previously reported...
February 16, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29403176/cytological-diagnosis-of-erythema-nodosum-leprosum-in-clinically-unsuspected-cases-a-report-of-two-cases
#3
Shruti Semwal, Deepti Joshi, Garima Goel, Neha Mittal, Kaushik Majumdar, Neelkamal Kapoor
Leprosy is a chronic infectious disease caused by Mycobacterium leprae. The manifestations of this disease varies across the spectrum of tuberculoid (TT) to lepromatous (LL) leprosy. The course of this indolent disease is interrupted by acute exacerbations in the form of leprare actions. Erythema nodosum leprosum (ENL), a type 2 lepra reaction, occurs in lepromatous or borderline lepromatous cases, usually in response to multidrug therapy. Early detection and timely management of these patients is important to reduce the associated morbidity...
January 2018: Journal of Cytology
https://www.readbyqxmd.com/read/29400291/erythema-nodosum-like-eruption-after-uterine-artery-embolization-a-case-report-and-literature-review
#4
Kensuke Yoneta, Norikazu Fujii, Shuichi Dendo, Takeshi Kato, Toshihiro Tanaka, Noriki Fujimoto
No abstract text is available yet for this article.
February 1, 2018: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29381943/acute-myeloid-leukemia-presenting-as-erythema-nodosum-a-case-report
#5
Xiaohan Xu, Guangyu Liang, Minghui Duan, Lu Zhang
RATIONALE: Erythema nodosum (EN), a type of septal panniculitis, could be a rare nonspecific cutaneous presentation of acute myeloid leukemia (AML). PATIENT CONCERNS: A 58-year-old Chinese female was admitted for a 4-week history of painful cutaneous lesions, accompanied by a sternal pain and fever. The lesions once resolved spontaneously but then recurred. Physical examination revealed warm, tender, indurated, rounded, erythematous to violaceous nodules in bilateral lower extremities, ranging in diameter from 1 to 6 cm...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29377079/incidence-of-diseases-primarily-affecting-the-skin-by-age-group-population-based-epidemiologic-study-in-olmsted-county-minnesota-and-comparison-with-age-specific-incidence-rates-worldwide
#6
REVIEW
Laurel L Wessman, Louise K Andersen, Mark D P Davis
Understanding the effects of age on the epidemiology of diseases primarily affecting the skin is important to the practice of dermatology, both for proper allocation of resources and for optimal patient-centered care. To fully appreciate the effect that age may have on the population-based calculations of incidence of diseases primarily affecting the skin in Olmsted County, Minnesota, and worldwide, we performed a review of all relevant Rochester Epidemiology Project-published data and compared them to similar reports in the worldwide English literature...
January 29, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29317571/erythema-nodosum-leprosum-necroticans
#7
Deepika Pandhi, Anita Kulhari
No abstract text is available yet for this article.
December 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/29315045/erythema-nodosum-leprosum
#8
Damian Bruce-Hickman, Adeline My Yong, Derrick Ac Wee, Nares Smitasin, Tan Kong Bin
No abstract text is available yet for this article.
January 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/29312877/diagnostic-contribution-of-magnetic-resonance-imaging-in-an-atypical-presentation-of-motor-neuron-disease
#9
Lorenzo Ugga, Cinzia Coppola, Sirio Cocozza, Dario Saracino, Ferdinando Caranci, Francesco Tuccillo, Elisabetta Signoriello, Sara Casertano, Giuseppe Di Iorio, Enrico Tedeschi
Motor neuron disease (MND) is a neurodegenerative disease determining progressive and relentless motor deterioration involving both upper and lower motor neurons (UMN and LMN); several variants at onset are described. Here we describe a case of MND presenting as pure spastic monoparesis in which magnetic resonance imaging (MRI) gave a substantial contribution in confirming the diagnosis and assessing the severity of UMN involvement. An isolated pyramidal syndrome, with complete absence of LMN signs, is a rare phenotype in the context of MND (less than 4% of total cases), especially if restricted to only one limb...
December 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29301808/skin-and-coeliac-disease-a-lot-to-think-about-a-case-series
#10
Sara O Vaz, Catarina Franco, Patrícia Santos, Raquel Amaral
Coeliac disease (CD) is an autoimmune disease, characterised by a permanent sensitivity to gluten. It is being progressively recognised as a multisystemic disease, with multiple extraintestinal manifestations. Skin conditions (eg, dermatitis herpetiformis) are an example of its manifestations; however, its underlying mechanisms are still not well understood. This article presents three cases of uncommon skin conditions in patients with a history of CD. Two of them concern linear IgA bullous dermatosis and erythema nodosum, which have been described in the literature as having potential associations with CD, though only a few cases were reported...
January 4, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29285050/thalidomide-and-its-analogues-a-review-of-the-potential-for-immunomodulation-of-fibrosis-diseases-and-opthalmopathy
#11
Ting Liu, Feng Guo, Xiaomin Zhu, Xiangge He, Lin Xie
The US Food and Drug Administration approved thalidomide and its analogues for the treatment of erythema nodosum leprosum, in spite of the notoriety of reports of severe birth defects in the middle of the last century. As immunomodulatory drugs, thalidomide and its analogues have been used to effectively treat various diseases. In the present review, preclinical data about the effects of thalidomide and its analogues on the immune system are integrated, including the effects of cytokines on transdifferentiation, the anti-inflammatory effect, immune cell function regulation and angiogenesis...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29234719/compression-stockings-as-an-effective-treatment-for-erythema-nodosum-case-series
#12
K B Golisch, S P Gottesman, R J Segal
Erythema nodosum (EN) is a septal panniculitis that is characterized clinically by tender, erythematous, subcutaneous nodules that are predominately localized on the pretibial lower legs. EN affects women more than men and can be idiopathic or secondary to another disease process such as infection or an immune response. Treatment options for erythema nodosum are suboptimal and often involve significant side effects or require a change in lifestyle. We investigated the effects of moderate 20 mmHg to 30 mmHg compression stockings as an alternative treatment method in two female patients with recurrent erythema nodosum...
December 2017: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/29204408/necrotic-erythema-nodosum-leprosum-healing-with-extensive-scars
#13
Chandra S Sirka, Maitreyee Panda, Swetalina Pradhan, Manas R Baisakh
No abstract text is available yet for this article.
November 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29194792/mucocutaneous-manifestations-of-inflammatory-bowel-disease-in-central-china-a-single-center-study
#14
C X Kou, Y Y Zhang, G W Li, J Li, Q T Kong, J Chen, F Liu, M Zhang, F Y Wang, Y Jiang, L Y Hao, J A Ren, H Sang
Inflammatory bowel disease (IBD) is a group of idiopathic inflammatory conditions affecting the gastrointestinal tract, which consists of Crohn's disease (CD) and ulcerative colitis (UC). IBD has multiple extraintestinal manifestations (EIMs), and the prevalence of mucocutaneous manifestations in IBD has been reported as 21%-41%1 . This study aimed at investigating the prevalence of mucocutaneous manifestations (recurrent aphthous ulcer [RAU], erythema nodosum [EN], psoriasis and pyoderma gangrenosum [PG]) of IBD and analyzing of the associations of diseases in a large treatment center of central China...
December 1, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29182760/expression-patterns-of-tnf%C3%AE-madcam1-and-stat3-in-intestinal-and-skin-manifestations-of-inflammatory-bowel-disease
#15
Stephan R Vavricka, Jose A Galván, Heather Dawson, Alex Soltermann, Luc Biedermann, Michael Scharl, Alain M Schoepfer, Gerhard Rogler, Mareike B Prinz Vavricka, Luigi Terracciano, Alexander Navarini, Inti Zlobec, Alessandro Lugli, Thomas Greuter
Background: Pathogenesis of cutaneous extraintestinal manifestations (EIM) in inflammatory bowel disease (IBD) remains elusive. Efficacy of anti-TNF agents suggests TNF-dependent mechanisms. The role of other biologics such as anti-integrins or JAK-inhibitors is not yet clear. Methods: We performed immunohistochemistry for TNFα, NFκB, STAT1/STAT3, MAdCAM1, CD20/68, caspase 3/9, IFNγ, Hsp-27/70 on 240 intestinal (55 controls, 185 IBD) and 64 skin biopsies (11 controls, 18 Erythema nodosum (EN), 13 Pyoderma gangenosum (PG), 22 psoriasis)...
November 22, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29181207/mycoplasma-pneumonia-an-unrecognized-cause-of-fever-of-unknown-origin-in-an-adult
#16
Fatima Ali-Ahmed, Alexandra Halalau
A 26-year-old female was admitted for fever of unknown origin (FUO), headaches, left ankle edema, and a lower extremity rash consistent with erythema nodosum. She had no respiratory symptoms or family history of autoimmune diseases. A chest X-ray was negative for pneumonia or hilar adenopathy. Extensive autoimmune workup was negative. A chest, abdomen, and pelvis computed tomography scan was unremarkable and laboratory studies revealed no source of infection. On hospital day 5, the patient developed a mild productive cough...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29151337/coexistence-of-idiopathic-granulomatous-mastitis-and-erythemanodosum-successful-treatment-with-corticosteroids
#17
Murat Akın, Harun Karabacak, Güldal Esendağlı, Aydın Yavuz, Serap Gültekin, Kürşat Dikmen, Hasan Bostancı
Background/aim: Idiopathic granulomatous mastitis (IGM) is a rare, chronic inflammatory disease of the breast. Erythema nodosum (EN) is a rare extramammary manifestation of IGM. The purpose of this study is to determine the clinical and demographic characteristics of 11 IGM and EN patients and to evaluate the efficacy of methylprednisolone treatment. Materials and methods: In our series, ten patients had EN bilaterally, whereas one patient had a lesion of the right pretibial area. The mean age of the patients was 35...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29090057/leprosy-presenting-with-iridocyclitis-a-diagnostic-dilemma
#18
Jaya Kaushik, Vaibhav Kumar Jain, Jitendra Kumar Singh Parihar, Sanjay Dhar, Savita Agarwal
PURPOSE: To report a case of lepromatous iridocyclitis that posed a diagnostic challenge. CASE REPORT: A 50-yeasr-old male developed profound loss of vision in the right eye, while he was in the hospital with septicemia presenting with fever, dysuria, and abdominal swelling. He also developed erythema nodosum on the legs. Skin incisional biopsy section, upon dermatology consultation, showed a granulomatous nodule in the dermis. The anterior chamber aspirate demonstrated lepra bacilli, which confirmed the diagnosis of lepromatous leprosy with type II reaction...
October 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29028793/clinico-pathological-features-of-erythema-nodosum-leprosum-a-case-control-study-at-alert-hospital-ethiopia
#19
Edessa Negera, Stephen L Walker, Selfu Girma, Shimelis N Doni, Degafe Tsegaye, Saba M Lambert, Munir H Idriss, Yohanis Tsegay, Hazel M Dockrell, Abraham Aseffa, Diana N Lockwood
BACKGROUND: Leprosy reactions are a significant cause of morbidity in leprosy population. Erythema nodosum leprosum (ENL) is an immunological complication affecting approximately 50% of patients with lepromatous leprosy (LL) and 10% of borderline lepromatous (BL) leprosy. ENL is associated with clinical features such as skin lesions, neuritis, arthritis, dactylitis, eye inflammation, osteitis, orchitis, lymphadenitis and nephritis. ENL is treated mainly with corticosteroids and corticosteroids are often required for extended periods of time which may lead to serious adverse effects...
October 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29016342/case-report-histoplasmosis-in-himachal-pradesh-india-an-emerging-endemic-focus
#20
Vikram K Mahajan, Rashmi Kaul Raina, Suman Singh, Rattan Sagar Rashpa, Anuradha Sood, Pushpinder S Chauhan, Karaninder S Mehta, Ritu Rawat, Vikas Sharma
We describe four cases of histoplasmosis indigenous to Himachal Pradesh (India) that will be of considerable public health interest. A 48-year-old human immunodeficiency virus (HIV)-negative man with cervical and mediastinal lymphadenopathy, hepatosplenomegaly, adrenal mass, and bone marrow involvement was treated as disseminated tuberculosis without benefit. Progressive disseminated histoplasmosis was diagnosed from the fungus in smears from adrenal mass. Another 37-year-old HIV-positive man was on treatment of suspected pulmonary tuberculosis...
September 25, 2017: American Journal of Tropical Medicine and Hygiene
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