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erythema nodosum

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https://www.readbyqxmd.com/read/29644775/exploring-the-combination-of-sski-and-topical-heparin-in-a-case-of-erythema-nodosum-migrans
#1
Manu Sehrawat, Niharika Dixit, Kabir Sardana, Purnima Malhotra
Erythema nodosum migrans (subacute nodular migratory panniculitis) is an uncommon type of panniculitis characterized by migrating subcutaneous nodules or plaque on the lower extremity. There are a very few cases of Erythema nodosum migrans reported and thus its appropriate treatment modality is not defined. We describe a case of a 30-year-old male with idiopathic erythema nodosum migrans which was manifest centrifugally spreading, slightly morpheaform erythematous plaque on the lower left leg. The patient was diagnosed initially and treated as a case of furunculosis with poor clinical response...
April 11, 2018: Dermatologic Therapy
https://www.readbyqxmd.com/read/29606414/poststreptococcal-reactive-arthritis-in-japan
#2
Maria Nishibukuro, Norito Tsutsumi, Masako Chiyotanda, Tae Hijikata, Shinichiro Morichi, Soupei Go, Gaku Yamanaka, Yasuyo Kashiwagi, Hisashi Kawashima
Reactive arthritis after Group A streptococcal infection (poststreptococcal reactive arthritis: PSRA) that does not meet the Jones criteria for acute rheumatic fever (ARF) has been reported as a new entity for over a decade. In Japan there are few reports of PSRA. We encountered four children with arthritis accompanied with Group A streptococcal infection in our department. We investigated our cases and the recent Japanese literature. Japanese cases of PSRA are frequently accompanied with uveitis and erythema nodosum, and tonsillectomy resolved their symptoms in some cases...
March 29, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29545439/unusual-association-between-erythema-nodosum-and-autoimmune-atrophic-gastritis
#3
Gisela Eugénio, Joao Tavares, Joana Fonseca Ferreira, Armando Malcata
We report a case of a 46-year-old woman with a history of autoimmune atrophic gastritis and recurrent erythema nodosum (EN). Laboratory results showed iron-deficiency anaemia, positive antiparietal cell antibodies and marginal deficiency of vitamin B12. Although EN was refractory to general measures (rest and non-steroidal anti-inflammatory drugs) and corticosteroid therapy, it was successfully treated with vitamin B12 supplementation.
March 15, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29516895/reactive-perforating-leprosy-erythema-multiforme-like-reactions-sweet-s-syndrome-like-reactions-as-atypical-clinical-manifestations-of-type-2-leprosy-reaction
#4
Hendra Gunawan, Yuri Yogya, Risty Hafinah, Rachel Marsella, Devi Ermawaty, Oki Suwarsa
Type 2 leprosy reactions commonly known as erythema nodosum leprosum, but various clinical manifestations of type 2 leprosy reaction were exist. The highlight of this case series was to report various atypical clinical manifestations of type 2 leprosy reaction such as reactive perforating leprosy, erythema multiforme-like reaction, and sweet's syndrome (SS)-like reaction.
January 2018: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/29503950/surgical-interventions-for-late-ocular-complications-of-relapsing-polychondritis
#5
Yuan He, Huifeng Liu, Zhi Ji, Binliang Zhu
Purpose: To report a case of surgical interventions for a patient with relapsing polychondritis who presented with late ocular complications. Observations: A 44-year-old male was diagnosed to have relapsing polychondritis on the basis of recurrent acute auricular chondritis, deformity of the ear, saddle nose deformity and painful nasal chondritis, acute ocular inflammation with conjunctivitis, episcleritis and keratouveitis, laryngotracheal chondritis, erythema nodosum in the skin, a history of polyarthritis, and abnormal blood examination findings...
April 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29499046/complement-c1q-expression-in-erythema-nodosum-leprosum
#6
Edessa Negera, Stephen L Walker, Tsehainesh Lemma, Abraham Aseffa, Diana N Lockwood, Hazel M Dockrell
Complement C1q is a soluble protein capable of initiating components of the classical pathway in host defence system. In earlier qualitative studies, C1q has been implicated in the pathogenesis of Erythema Nodosum Leprosum (ENL). However, little is known about the role of this complement in ENL reaction. In the present study we described the protein level of C1q production and its gene expression in the peripheral blood and skin biopsies in patients with ENL reaction and lepromatous leprosy (LL) patient controls before and after treatment...
March 2, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29484571/effects-of-vedolizumab-therapy-on-extraintestinal-manifestations-in-inflammatory-bowel-disease
#7
REVIEW
Mark Fleisher, Jan Marsal, Scott D Lee, Laura E Frado, Alyssa Parian, Burton I Korelitz, Brian G Feagan
BACKGROUND: Approximately 15-20% of ulcerative colitis patients and 20-40% of those with Crohn's disease experience extraintestinal manifestations (EIMs) of their inflammatory bowel disease (IBD). Clinicians who treat IBD must manage EIMs affecting multiple organs that variably correlate with intestinal disease activity. Vedolizumab is a monoclonal antibody for the treatment of IBD with a gut-selective mechanism of action. AIMS: This report evaluates whether vedolizumab is an effective treatment of EIMs, given its gut-specific mechanism of action...
February 26, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29479352/the-effects-of-prednisolone-treatment-on-cytokine-expression-in-patients-with-erythema-nodosum-leprosum-reactions
#8
Edessa Negera, Stephen L Walker, Kidist Bobosha, Yonas Bekele, Birtukan Endale, Azeb Tarekegn, Markos Abebe, Abraham Aseffa, Hazel M Dockrell, Diana N Lockwood
Erythema nodosum leprosum (ENL) is a systemic inflammatory complication occurring mainly in patients with lepromatous leprosy (LL) and borderline lepromatous leprosy. Prednisolone is widely used for treatment of ENL reactions but clinical improvement varies. However, there is little good in vivo data as to the effect of prednisolone treatment on the pro-inflammatory cytokines in patients with ENL reactions. As a result, treatment and management of reactional and post-reactional episodes of ENL often pose a therapeutic challenge...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29474830/erythema-nodosum-leprosum-update-and-challenges-on-the-treatment-of-a-neglected-condition
#9
REVIEW
Perpétua do Socorro Silva Costa, Lucas Rosa Fraga, Thayne Woycinck Kowalski, Egon Luiz Rodrigues Daxbacher, Lavínia Schuler-Faccini, Fernanda Sales Luiz Vianna
Erythema Nodosum Leprosum (ENL) occurs due to the immunological complication of multibacillary leprosy and is characterized by painful nodules and systemic compromising. It is usually recurrent and/or chronic and has both physical and economic impact on the patient, being a very important cause of disability. In addition, ENL is a major health problem in countries where leprosy is endemic. Therefore, adequate control of this condition is important. The management of ENL aims to control acute inflammation and neuritis and prevent the onset of new episodes...
February 20, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29471416/anti-interleukin-6-receptor-tocilizumab-in-refractory-uveitis-associated-with-beh%C3%A3-et-s-disease-multicentre-retrospective-study
#10
Belén Atienza-Mateo, Vanesa Calvo-Río, Emma Beltrán, Lucía Martínez-Costa, Elia Valls-Pascual, Marisa Hernández-Garfella, Antonio Atanes, Miguel Cordero-Coma, Joan Miquel Nolla, Carmen Carrasco-Cubero, Javier Loricera, María C González-Vela, Nuria Vegas-Revenga, Carlos Fernández-Díaz, Rosalía Demetrio-Pablo, Lucía C Domínguez-Casas, José Luis Martín-Varillas, Natalia Palmou-Fontana, José L Hernández, Miguel Á González-Gay, Ricardo Blanco
Objective: To assess the efficacy of tocilizumab (TCZ) in refractory uveitis of Behçet's disease (BD). Methods: Multicentre study of patients with BD-associated uveitis. Patients were refractory to conventional and biologic immunosuppressive drugs. The main outcome measures were intraocular inflammation, macular thickness, visual acuity and corticosteroid-sparing effects. Results: We studied 11 patients (7 men) (20 affected eyes); median age 35 years...
February 19, 2018: Rheumatology
https://www.readbyqxmd.com/read/29453869/erythema-nodosum-like-eruption-in-the-setting-of-sorafenib-therapy
#11
Emily L Coleman, Shawn E Cowper, Stacey M Stein, Jonathan S Leventhal
No abstract text is available yet for this article.
February 16, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29453213/the-cat-did-it-erythema-nodosum-and-additional-atypical-presentations-of-bartonella-henselae-infection-in-immunocompetent-hosts
#12
Ami Schattner, Livnat Uliel, Ina Dubin
A healthy patient presented with painful skin lesions on the anterior surface of her legs. Erythema nodosum was diagnosed but all the usual causes were ruled out. The finding of bilateral enlarged axillary lymph nodes with necrosis and granulomas led to the diagnosis of Bartonella infection, an unusual cause of erythema nodosum. Imaging also revealed splenomegaly and small para-aortic lymph nodes. Up to one quarter of the patients with cat-scratch disease present atypically, a considerably higher prevalence than previously reported...
February 16, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29403176/cytological-diagnosis-of-erythema-nodosum-leprosum-in-clinically-unsuspected-cases-a-report-of-two-cases
#13
Shruti Semwal, Deepti Joshi, Garima Goel, Neha Mittal, Kaushik Majumdar, Neelkamal Kapoor
Leprosy is a chronic infectious disease caused by Mycobacterium leprae. The manifestations of this disease varies across the spectrum of tuberculoid (TT) to lepromatous (LL) leprosy. The course of this indolent disease is interrupted by acute exacerbations in the form of leprare actions. Erythema nodosum leprosum (ENL), a type 2 lepra reaction, occurs in lepromatous or borderline lepromatous cases, usually in response to multidrug therapy. Early detection and timely management of these patients is important to reduce the associated morbidity...
January 2018: Journal of Cytology
https://www.readbyqxmd.com/read/29400291/erythema-nodosum-like-eruption-after-uterine-artery-embolization-a-case-report-and-literature-review
#14
Kensuke Yoneta, Norikazu Fujii, Shuichi Dendo, Takeshi Kato, Toshihiro Tanaka, Noriki Fujimoto
No abstract text is available yet for this article.
February 1, 2018: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29381943/acute-myeloid-leukemia-presenting-as-erythema-nodosum-a-case-report
#15
Xiaohan Xu, Guangyu Liang, Minghui Duan, Lu Zhang
RATIONALE: Erythema nodosum (EN), a type of septal panniculitis, could be a rare nonspecific cutaneous presentation of acute myeloid leukemia (AML). PATIENT CONCERNS: A 58-year-old Chinese female was admitted for a 4-week history of painful cutaneous lesions, accompanied by a sternal pain and fever. The lesions once resolved spontaneously but then recurred. Physical examination revealed warm, tender, indurated, rounded, erythematous to violaceous nodules in bilateral lower extremities, ranging in diameter from 1 to 6 cm...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29377079/incidence-of-diseases-primarily-affecting-the-skin-by-age-group-population-based-epidemiologic-study-in-olmsted-county-minnesota-and-comparison-with-age-specific-incidence-rates-worldwide
#16
REVIEW
Laurel L Wessman, Louise K Andersen, Mark D P Davis
Understanding the effects of age on the epidemiology of diseases primarily affecting the skin is important to the practice of dermatology, both for proper allocation of resources and for optimal patient-centered care. To fully appreciate the effect that age may have on the population-based calculations of incidence of diseases primarily affecting the skin in Olmsted County, Minnesota, and worldwide, we performed a review of all relevant Rochester Epidemiology Project-published data and compared them to similar reports in the worldwide English literature...
January 29, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29317571/erythema-nodosum-leprosum-necroticans
#17
Deepika Pandhi, Anita Kulhari
No abstract text is available yet for this article.
December 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/29315045/erythema-nodosum-leprosum
#18
Damian Bruce-Hickman, Adeline My Yong, Derrick Ac Wee, Nares Smitasin, Tan Kong Bin
No abstract text is available yet for this article.
January 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/29312877/diagnostic-contribution-of-magnetic-resonance-imaging-in-an-atypical-presentation-of-motor-neuron-disease
#19
Lorenzo Ugga, Cinzia Coppola, Sirio Cocozza, Dario Saracino, Ferdinando Caranci, Francesco Tuccillo, Elisabetta Signoriello, Sara Casertano, Giuseppe Di Iorio, Enrico Tedeschi
Motor neuron disease (MND) is a neurodegenerative disease determining progressive and relentless motor deterioration involving both upper and lower motor neurons (UMN and LMN); several variants at onset are described. Here we describe a case of MND presenting as pure spastic monoparesis in which magnetic resonance imaging (MRI) gave a substantial contribution in confirming the diagnosis and assessing the severity of UMN involvement. An isolated pyramidal syndrome, with complete absence of LMN signs, is a rare phenotype in the context of MND (less than 4% of total cases), especially if restricted to only one limb...
December 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29301808/skin-and-coeliac-disease-a-lot-to-think-about-a-case-series
#20
Sara O Vaz, Catarina Franco, Patrícia Santos, Raquel Amaral
Coeliac disease (CD) is an autoimmune disease, characterised by a permanent sensitivity to gluten. It is being progressively recognised as a multisystemic disease, with multiple extraintestinal manifestations. Skin conditions (eg, dermatitis herpetiformis) are an example of its manifestations; however, its underlying mechanisms are still not well understood. This article presents three cases of uncommon skin conditions in patients with a history of CD. Two of them concern linear IgA bullous dermatosis and erythema nodosum, which have been described in the literature as having potential associations with CD, though only a few cases were reported...
January 4, 2018: BMJ Case Reports
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