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Jorge Canena
No abstract text is available yet for this article.
January 2018: GE Portuguese Journal of Gastroenterology
Charles Penner
"It was the best of times, it was the worst of times, it was the age of wisdom, it was the age of foolishness, it was the epoch of belief, it was the epoch of incredulity." The opening line of Dickens's A Tale of Two Cities could easily be the dramatic opening line of a summary of the establishment of a satellite medical school campus in Manitoba. Reflection on my last four years as associate dean reveals that most of the descriptors in that famous sentence at one time or another were apropos. This brief essay will relate the experiences of the last four years and some of the lessons learned along the way...
February 16, 2018: Medical Teacher
Matthew Salter, Michael Thoennessen
No abstract text is available yet for this article.
January 2018: Physical Review. E
Gregory A L Davies, Larry A Wolfe, Michelle F Mottola, Catherine MacKinnon
OBJECTIF: Énoncer une directive canadienne visant à informer les fournisseurs de soins obstétricaux des répercussions, pour la mère, le fœtus et le nouveau-né, des exercices de conditionnement aerobique et musculaire pendant la grossesse. RéSULTATS ATTENDUS: Effets sur la morbidité maternelle, fœtale et néonatale et mesures de la forme physique maternelle. PREUVES: Une recherche sur MEDLINE des articles, publiés en anglais de 1966 à 2002, appartenant aux catégories suivantes : études sur le conditionnement aérobique et musculaire chez des femmes ne faisant pas jusque-là d'exercice et chez des femmes actives avant leur grossesse, ainsi que des études sur les répercussions du conditionnement aérobique et musculaire sur les issues précoces et tardives de la grossesse ou sur les issues néonatales; rapports de synthèse et méta-analyses portant sur l'exercice pendant la grossesse...
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Kenneth Lim, Kimberly Butt, Joan M Crane
No abstract text is available yet for this article.
February 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Nicole De Simone, Ravi Sarode
Tunneled central venous catheters with ports are increasingly used for therapeutic apheresis procedures. Vortex ports have been used as access for therapeutic apheresis procedures, but are not ideal for therapeutic plasma exchange (TPE) procedures due to lower flow rates. We performed an in vitro experiment to compare flow characteristics of the single-lumen Vortex port (AngioDynamics) with the single-lumen TidalPort (Norfolk Medical). We used expired red blood cell units and adjusted the hematocrit to 40% with normal saline in a 2-L bag...
February 2018: Transfusion
Alle A Y Lie, Zhenfeng Liu, Ramon Terrado, Avery O Tatters, Karla B Heidelberg, David A Caron
Ochromonas spp. strains CCMP1393 and BG-1 are phagotrophic phytoflagellates with different nutritional strategies. Strain CCMP1393 is an obligate phototroph while strain BG-1 readily grows in continuous darkness in the presence of bacterial prey. Growth and gene expression of strain CCMP1393 were investigated under conditions allowing phagotrophic, mixotrophic, or phototrophic nutrition. The availability of light and bacterial prey led to the differential expression of 42% or 45-59% of all genes, respectively...
2018: PloS One
Zhonghui Zhang, Wen-Shu Wu
MicroRNAs are small 18-24 nt single-stranded noncoding RNA molecules involved in many biological processes, including stemness maintenance and cellular reprogramming. Current methods used in loss-of-function studies of microRNAs have several limitations. Here, we describe a new approach for dissecting miR-302/367 functions by transcription activator-like effectors (TALEs), which are natural effector proteins secreted by Xanthomonas and Ralstonia bacteria. Knockdown of the miR-302/367 cluster uses the Kruppel-associated box repressor domain fused with specific TALEs designed to bind the miR-302/367 cluster promoter...
2018: Methods in Molecular Biology
Richard Kahn
No abstract text is available yet for this article.
February 13, 2018: Annals of Internal Medicine
Ashley York
No abstract text is available yet for this article.
February 12, 2018: Nature Reviews. Microbiology
Katherine M Keyes
No abstract text is available yet for this article.
March 2018: Addiction
Miklos D Kertai, Andrew D Shaw
No abstract text is available yet for this article.
February 8, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
Jannell V Bazurto, Stephen P Dearth, Eric D Tague, Shawn R Campagna, Diana M Downs
In Salmonella enterica, aminoimidazole carboxamide ribotide (AICAR) is a purine biosynthetic intermediate and a substrate of the AICAR transformylase/IMP cyclohydrolase (PurH) enzyme. When purH is eliminated in an otherwise wild-type strain, AICAR accumulates and indirectly inhibits synthesis of the essential coenzyme thiamine pyrophosphate (TPP). In this study, untargeted metabolomics approaches were used to i) corroborate previously defined metabolite changes, ii) define the global consequences of AICAR accumulation and iii) investigate the metabolic effects of mutations that restore thiamine prototrophy to a purH mutant...
November 22, 2017: Microbial Cell
Sossena Wood, Narayanan Krishnamurthy, Tales Santini, Shailesh B Raval, Nadim Farhat, John Andy Holmes, Tamer S Ibrahim
[This corrects the article DOI: 10.1371/journal.pone.0183168.].
2018: PloS One
Laura Tensen, Rosemary J Groom, Joy Khuzwayo, Bettine Jansen van Vuuren
The rapid decline of the African lion (Panthera leo) has raised conservation concerns. In the Savé Valley Conservancy (SVC), in the Lowveld of Zimbabwe, lions were presumably reduced to approximately 5 to 10 individuals. After ten lions were reintroduced in 2005, the population has recovered to over 200 lions in 2016. Although the increase of lions in the SVC seems promising, a question remains whether the population is genetically viable, considering their small founding population. In this study, we document the genetic diversity in the SVC lion population using both mitochondrial and nuclear genetic markers, and compare our results to literature from other lion populations across Africa...
2018: PloS One
Matthew A Kolmann, Jonathan M Huie, Kory Evans, Adam P Summers
Although rare within the context of 30 000 species of extant fishes, scale-feeding as an ecological strategy has evolved repeatedly across the teleost tree of life. Scale-feeding (lepidophagous) fishes are diverse in terms of their ecology, behaviour, and specialized morphologies for grazing on scales and mucus of sympatric species. Despite this diversity, the underlying ontogenetic changes in functional and biomechanical properties of associated feeding morphologies in lepidophagous fishes are less understood...
January 2018: Royal Society Open Science
Christina Neppl, Bernhard Friedli, Ekkehard Hewer
No abstract text is available yet for this article.
January 31, 2018: Gastroenterology
Yizhan Guo, Alexander Sasha Krupnick
No abstract text is available yet for this article.
December 23, 2017: Journal of Thoracic and Cardiovascular Surgery
Stanley F Wainapel, Hilary C Siebens
No abstract text is available yet for this article.
February 3, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
Andrés Ernesto Ortiz-Rodriguez, Juan Francisco Ornelas, Eduardo Ruiz-Sanchez
The predominantly Asian tribe Miliuseae (Annonaceae) includes over 37 Neotropical species that are mainly distributed across Mesoamerica, from southern Mexico to northern Colombia. The tremendous ecological and morphological diversity of this clade, including ramiflory, cauliflory, flagelliflory, and clonality, suggests adaptive radiation. Despite the spectacular phenotypic divergence of this clade, little is known about its phylogenetic and evolutionary history. In this study we used a nuclear DNA marker and seven chloroplast markers, and maximum parsimony, maximum likelihood and Bayesian inference methods to reconstruct a comprehensive time-calibrated phylogeny of tribe Miliuseae, especially focusing on the Desmopsis-Stenanona clade...
January 30, 2018: Molecular Phylogenetics and Evolution
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