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https://www.readbyqxmd.com/read/28811115/recurrence-of-cutaneous-coccidioidomycosis-6-years-after-valley-fever-a-case-presentation-and-literature-review
#1
Rana Shahab, Nasir K Amra, Rola Rabah, Justin Saunar, Joan Soriano, Jaffar A Al-Tawfiq
Coccidioidomycosis is usually acquired by inhalation of spores of Coccidioides immitis and C. posadasii. The disease ranges from a self-limited acute pneumonia (Valley Fever) to a disseminated disease. We present a 44-year-old healthy male who had patchy hair loss of several months duration resembling discoid lupus. He developed a firm non-scaly red plaque on the right forehead. Initial biopsy showed spongiotic dermatitis, and he was treated with systemic steroids. He then developed forehead and periorbital cellulitis and was treated with systemic antibiotics...
July 8, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28797486/diagnosis-and-management-of-coccidioidomycosis
#2
REVIEW
Luke M Gabe, Joshua Malo, Kenneth S Knox
Coccidioidomycosis is a leading cause of community-acquired pneumonia within its traditional endemic zone in the Southwestern United States and portions of Mexico and Central and South America. Its incidence has increased dramatically within the endemic region; its presence outside of the region, facilitated by a mobile society, is also now substantial. Although only a fraction of the incident disease progresses beyond subclinical illness, this proportion is large in absolute terms and causes substantial disease burden...
September 2017: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/28796756/notes-from-the-field-increase-in-coccidioidomycosis-california-2016
#3
Gail Sondermeyer Cooksey, Alyssa Nguyen, Kirsten Knutson, Farzaneh Tabnak, Kaitlin Benedict, Orion McCotter, Seema Jain, Duc Vugia
Coccidioidomycosis, or Valley Fever, is an infectious disease caused by inhalation of Coccidioides spp. spores (1). This soil-dwelling fungus is endemic in the southwestern United States, with most (97%) U.S. cases reported from Arizona and California (1,2). Following an incubation period of 1-3 weeks, symptomatic patients most often experience self-limited, influenza-like symptoms, but coccidioidomycosis also can lead to severe pulmonary disease and to rare cases of disseminated disease, including meningitis (1)...
August 11, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28769594/disseminated-coccidioidomycosis-with-molluscum-like-lesions-diffuse-lymphadenopathy-and-splenomegaly-in-an-immunocompetent-patient
#4
Ernest Fonocho, Richard Murray, Nail Aydin
Coccidioidomycosis is caused by a dimorphic fungus species endemic to the arid and semi-arid regions of the Americas. The species have a terranean habitat producing a primary pulmonary infection by inhalation of arthroconidia. We describe a case of extrapulmonary coccidioidomycosis presenting with extensive lymphadenopathy, splenomegaly, and florid cutaneous lesions. This case is intended to heighten clinical suspicion in patients with risk factors.
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28720194/you-re-the-flight-surgeon
#5
(no author information available yet)
Harris Graessle CL. You're the flight surgeon: coccidioidomycosis. Aerosp Med Hum Perform. 2017; 88(8):796-800.
August 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28717672/coccidioidomycosis-a-cause-of-sarcoidosis
#6
Tim Kuberski, Isaac Yourison
BACKGROUND: Sarcoidosis is a granulomatous disease of unknown etiology and coccidioidomycosis is a granulomatous fungal infection endemic to the southwestern United States. Clinical observations on patients with sarcoidosis and coccidioidomycosis simultaneously led to the hypothesis that sarcoidosis can be caused by the fungus Coccidioides. METHODS: Two patients with sarcoidosis and coccidioidomycosis were studied, one prospectively (ie, a patient with sarcoidosis was predicted to develop coccidioidomycosis) and the other retrospectively (ie, a patient with coccidioidomycosis develops sarcoidosis)...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28702025/cellular-and-molecular-defects-underlying-invasive-fungal-infections-revelations-from-endemic-mycoses
#7
REVIEW
Pamela P Lee, Yu-Lung Lau
The global burden of fungal diseases has been increasing, as a result of the expanding number of susceptible individuals including people living with human immunodeficiency virus (HIV), hematopoietic stem cell or organ transplant recipients, patients with malignancies or immunological conditions receiving immunosuppressive treatment, premature neonates, and the elderly. Opportunistic fungal pathogens such as Aspergillus, Candida, Cryptococcus, Rhizopus, and Pneumocystis jiroveci are distributed worldwide and constitute the majority of invasive fungal infections (IFIs)...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28695649/single-center-experience-of-antifungal-prophylaxis-for-coccidioidomycosis-in-heart-transplant-recipients-within-an-endemic-area
#8
Graham M Lohrmann, Darko Vucicevic, Romy Lawrence, D Eric Steidley, Robert L Scott, Shimon Kusne, Janis E Blair
In endemic regions, coccidioidomycosis causes substantial morbidity and mortality for patients receiving solid organ transplants. We aimed to demonstrate the effect of antifungal coccidioidal prophylaxis in heart transplant (HT) recipients. We retrospectively reviewed the electronic health records of all patients who received HTs between October 19, 2005, and December 13, 2014. We collected information regarding antifungal regimens and determined whether patients subsequently developed infections. Our 174-person cohort all received antifungal prophylaxis for at least 6 months (mean follow-up, 53...
July 11, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28656821/increased-coccidioidomycosis-among-inmates-at-a-california-prison-initial-investigation-in-2005-to-2006
#9
Lauren A Lee, Jean Yuan, Duc Vugia, Charlotte Wheeler, Robert Chapnick, Janet Mohle-Boetani
Since 2005, coccidioidomycosis has increased among inmates at a California prison. Our initial investigation found an incidence of 3,323 cases/100,000 persons. Black race, age ≥41 years, and residence on Yard C were significantly associated with coccidioidomycosis ( p < .05). Inmates at this prison have continued to be at risk for coccidioidomycosis.
January 1, 2017: Journal of Correctional Health Care
https://www.readbyqxmd.com/read/28644403/assessment-of-vulnerability-to-coccidioidomycosis-in-arizona-and-california
#10
Jennifer Shriber, Kathryn C Conlon, Kaitlin Benedict, Orion Z McCotter, Jesse E Bell
Coccidioidomycosis is a fungal infection endemic to the southwestern United States, particularly Arizona and California. Its incidence has increased, potentially due in part to the effects of changing climatic variables on fungal growth and spore dissemination. This study aims to quantify the county-level vulnerability to coccidioidomycosis in Arizona and California and to assess the relationships between population vulnerability and climate variability. The variables representing exposure, sensitivity, and adaptive capacity were combined to calculate county level vulnerability indices...
June 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28640687/dust-exposure-and-coccidioidomycosis-prevention-among-solar-power-farm-construction-workers-in-california
#11
Gail L Sondermeyer Cooksey, Jason A Wilken, Jennifer McNary, Debra Gilliss, Dennis Shusterman, Barbara L Materna, Duc J Vugia
OBJECTIVES: To investigate if work activities, dust exposure, and protection measures were associated with a 2011 to 2014 coccidioidomycosis outbreak among workers constructing 2 solar farms in California. METHODS: In 2013, we mailed self-administered questionnaires to employees who were onsite at the solar farms where the outbreak occurred to identify cases of clinical coccidioidomycosis and compare with asymptomatic workers by using multivariate logistic regression...
August 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28611563/disseminated-coccidioidomycosis-presenting-as-carcinomatosis-peritonei-and-intestinal-coccidioidomycosis-in-a-patient-with-hiv
#12
Umer Malik, Hira Cheema, Ramcharitha Kandikatla, Yasir Ahmed, Kalyan Chakrala
Coccidioidomycosis (CM) is a fungal infection endemic in southwestern regions of the United States, northwestern regions of Mexico, and some areas of Brazil and Argentina. Clinical presentation varies depending on the extent of the infection and the immune status of the host. The most common presentation ranges from flu-like symptoms to self-limiting pneumonia. Extrapulmonary presentations are uncommon and may involve the meninges, skin, and bone. Gastrointestinal and peritoneal involvement is extremely rare...
January 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28595294/coccidioidomycosis-an-underreported-cause-of-death-arizona-2008-2013
#13
Jefferson M Jones, Lia Koski, Mohammed Khan, Shane Brady, Rebecca Sunenshine, Ken K Komatsu
In Arizona during 1997-2013, coccidioidomycosis increased from 21 to 90 cases/100,000 population, but coccidioidomycosis-associated deaths remained stable at 3-6 deaths/million population. We used the capture-recapture method by using death certificates and hospital discharge data to more fully estimate the total number of coccidioidomycosis-attributable deaths and compared this with published estimates. Death certificates were included if any cause of death included coccidioidomycosis; hospital discharge data deaths were included if any discharge diagnosis included coccidioidomycosis and laboratory confirmation...
June 8, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28584982/rational-design-of-t-lymphocyte-epitope-based-vaccines-against-coccidioides-infection
#14
Brady J Hurtgen, Chiung-Yu Hung
Coccidioidomycosis is a potentially life-threatening mycosis endemic to the Southwestern USA and some arid regions of Central and South America. A vaccine against Coccidioides infection would benefit over 30-million people who reside in or visit the endemic regions. Vaccine candidates against systemic fungal infections come in many forms. Live attenuated vaccines are derived from disease-causing pathogens and generally stimulate excellent protective immunity. Since attenuated vaccines contain living microbes, there is a degree of unpredictability raising concerns regarding safety and stability...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28577242/divergence-in-the-approach-to-tumor-necrosis-factor-%C3%AE-inhibitor-recipients-with-coccidioidomycosis
#15
Ashley L Garrett, Stephen S Cha, Elizabeth Wack, Janis E Blair
BACKGROUND: Tumor necrosis factor α-inhibitors (TNFIs) have been associated with increased risk of certain fungal infections, including coccidioidomycosis. The optimal treatment approach to coccidioidomycosis in TNFI recipients is unknown. METHODS: We constructed an anonymous, voluntary survey for practicing pulmonary and infectious disease physicians in the state of Arizona regarding approach to TNFI patients with coccidioidomycosis. RESULTS: There is no current consensus on managing these patients...
August 2017: Infection
https://www.readbyqxmd.com/read/28566083/-a-case-of-coccidioidomycosis-in-turkey-imported-from-the-united-states-of-america
#16
Seniha Başaran, Nilgün Karabıçak, Serap Şimşek Yavuz, Nathan P Wiederhold, Seda Şafak, Aysun Sarıbuğa, Deanna A Sutton, Züleyha Bingöl, Atahan Çağatay, Halit Özsüt, Zeki Kılıçaslan, Haluk Eraksoy
Coccidioidomycosis caused by Coccidioides immitis or Coccidioides posadasii is a rare infectious disease except in endemic regions. In this report the third documented imported case of coccidioidomycosis in Turkey was presented. A thirty-year-old male patient was admitted to our hospital with fever and purulent drainage from his chest tube. He had worked in Arizona, USA, until 4 months before this presentation. While in Arizona, he experienced cough and hemoptysis and was diagnosed as pulmonary coccidioidomycosis...
April 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28560172/a-case-of-osteomyelitis-of-the-toe-caused-by-coccidioidomycosis-in-a-17-year-old-with-diabetes-insipidus
#17
Ahmer Khalid, Daniel J Boken, Christine A Nelson, Vicken Y Totten
We report a case of a 17-year-old male who presented with pain in his right first toe. His pain and swelling had worsened and x-rays of his foot revealed erosive changes of the great toe distal phalanx suggesting possible osteomyelitis. His co-morbidities were morbid obesity and diabetes insipidus. He was admitted to the hospital, blood cultures were drawn, and he was started on vancomycin for presumed bacterial osteomyelitis. He underwent incision and drainage of the fluctuant abscess of the toe, where a culture of the wound was taken...
2017: IDCases
https://www.readbyqxmd.com/read/28507906/a-case-of-a-positive-coccidioides-stool-culture-in-an-immunocompetent-patient-with-disseminated-coccidioidomycosis
#18
Majd Alfreijat, Brian Wilhelmi
Coccidioidomycosis (CM) is an infection caused by the coccidioides fungus. The spectrum of the disease ranges from a mild upper respiratory illness to severe disseminated infection that could affects the bones, joints, skin, central nervous system, and the gastrointestinal tract. Previous reports of a positive stool culture in the setting of disseminated CM are extremely rare. Herein, we describe a case of a 43-year-old immunocompetent patient with disseminated CM and evidence of positive coccidioides stool culture...
2017: IDCases
https://www.readbyqxmd.com/read/28452423/coccidioidomycosis-among-persons-undergoing-lung-transplantation-in-the-coccidioidal-endemic-region
#19
Sachin Chaudhary, Laura Meinke, Huthayfa Ateeli, Kenneth S Knox, Yuval Raz, Neil M Ampel
BACKGROUND: Coccidioidomycosis, an endemic fungal infection, is more likely to be symptomatic and severe among those receiving allogeneic transplants. While several case series have been published for various transplanted organs, none has described the incidence and outcomes in those receiving lung transplants within the coccidioidal endemic region. METHODS: Patients receiving a heart-lung, single-lung, or bilateral-lung transplantation at the University of Arizona between 1985 and 2009 were retrospectively reviewed...
August 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28386282/ulcerated-lesion-of-the-tongue-as-manifestation-of-systemic-coccidioidomycosis
#20
Luis A Mendez, Sergio A Flores, Ricardo Martinez, Oslei Paes de Almeida
Systemic mycoses and their oral manifestations are very rare. We present a case of a 60-year-old man with an ulcerated lesion on the lateral border of the tongue. Histologic studies revealed a granulomatous fungal infection by Coccidioides immitis. After pharmacological treatment, the lesion resolved. Recently, northern Mexico has been reported to be an endemic zone of C. immitis infections; therefore it should be considered in the differential diagnosis of mouth lesions. A comprehensive clinical history, physical exploration, and complementary studies are essential for an accurate diagnosis...
2017: Case Reports in Medicine
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