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JOURNAL ARTICLE
Andreia Vasconcelos, Jonathan D King, Cláudio Nunes-Alves, Roy Anderson, Daniel Argaw, Maria-Gloria Basáñez, Shakir Bilal, David J Blok, Seth Blumberg, Anna Borlase, Oliver J Brady, Raiha Browning, Nakul Chitnis, Luc E Coffeng, Emily H Crowley, Zulma M Cucunubá, Derek A T Cummings, Christopher Neil Davis, Emma Louise Davis, Matthew Dixon, Andrew Dobson, Louise Dyson, Michael French, Claudio Fronterre, Emanuele Giorgi, Ching-I Huang, Saurabh Jain, Ananthu James, Sung Hye Kim, Klodeta Kura, Ana Lucianez, Michael Marks, Pamela Sabina Mbabazi, Graham F Medley, Edwin Michael, Antonio Montresor, Nyamai Mutono, Thumbi S Mwangi, Kat S Rock, Martha-Idalí Saboyá-Díaz, Misaki Sasanami, Markus Schwehm, Simon E F Spencer, Ariktha Srivathsan, Robert S Stawski, Wilma A Stolk, Samuel A Sutherland, Louis-Albert Tchuem Tchuenté, Sake J de Vlas, Martin Walker, Simon J Brooker, T Déirdre Hollingsworth, Anthony W Solomon, Ibrahima Socé Fall
Over the past decade, considerable progress has been made in the control, elimination, and eradication of neglected tropical diseases (NTDs). Despite these advances, most NTD programs have recently experienced important setbacks; for example, NTD interventions were some of the most frequently and severely impacted by service disruptions due to the coronavirus disease 2019 (COVID-19) pandemic. Mathematical modeling can help inform selection of interventions to meet the targets set out in the NTD road map 2021-2030, and such studies should prioritize questions that are relevant for decision-makers, especially those designing, implementing, and evaluating national and subnational programs...
April 25, 2024: Clinical Infectious Diseases
#22
JOURNAL ARTICLE
Camila Alves Dos Santos, Joanir Pereira Eler, Elisangela Chicaroni de Mattos Oliveira, Rafael Espigolan, Gabriela Giacomini, José Bento Sterman Ferraz, Tiago do Prado Paim
Genomic regions related to tropical adaptability are of paramount importance for animal breeding nowadays, especially in the context of global climate change. Moreover, understanding the genomic architecture of these regions may be very relevant for aiding breeding programs in choosing the best selection scheme for tropical adaptation and/or implementing a crossbreeding scheme. The composite MONTANA TROPICAL® population was developed by crossing cattle of four different biological types to improve production in harsh environments...
2024: PloS One
#23
JOURNAL ARTICLE
Eric Tchouaket, Katya Kruglova, Isidore Sieleunou, Marcellin Tsafack, Joseph Maabo Tankwa, Gislaine Takoguen, Nikolas Argiropoulos, Stephanie Robins, Drissa Sia
There are many healthcare financing programs (HFPs) in Cameroon; however, there is a lack of information on these programs' economic effectiveness and efficiency. Involvement of local stakeholders in the economic evaluations (EEs) of HFPs is critical for ensuring contextual factors are considered prior to program implementation. We conducted a cross-sectional study to assess the need for EEs of Cameroonian HFPs. Regular staff in supervisory roles aged 18 years and above were recruited in four Cameroonian cities...
2024: PLOS Glob Public Health
#24
JOURNAL ARTICLE
Qian Chen, Xuejian Yang, Dan Yang, Sen Liu, Chuchu Liao
In view of the rapid development and application of blockchain technology, this paper considers a secondary supply chain system consisting of a single upstream supplier and a downstream e-tailer that implements blockchain technology and a traditional e-tailer that does not implement blockchain technology. We establish the demand function of two channels based on consumers' sensitivity to the blockchain and use the Stackelberg game model to compare and analyse the e-tailers' profits from the two channels. For the basic properties, interestingly, we find that there exists a critical threshold on the cost sensitivity to effort that helps each e-tailer decide whether to implement effort...
2024: PloS One
#25
JOURNAL ARTICLE
Fang Li
Intellectual property is crucial for the development of firms. At the micro level, firm comprehensive intellectual property ability involves abilities about intellectual property creation, utilization, protection, and management. In order to develop the comprehensive intellectual property ability of firms, the China National Intellectual Property Administration began to implement the national intellectual property demonstration advantage firm (NIPDAF) policy in 2013. Based on this exogenous policy shock, using data from listed companies from 2011 to 2020 as the research sample, the time-varying DID method is used to test the impact of the NIPDAF policy intended to cultivate comprehensive intellectual property ability on firm productivity...
2024: PloS One
#26
JOURNAL ARTICLE
Tayyab Khan, Long Wei, Ayesha Khan, Mochammad Fahlevi, Mohammed Aljuaid, Sher Ali
To encourage technological and industrial innovation, nations worldwide implement "re-industrialization" and "manufacturing return." This study investigates the relationship between GDP growth, expenditure on research and development, and medium- to high-tech as a percentage of manufactured exports on technological innovation in Pakistan. We evaluated long-run and short-run causal relationships using the ARDL, bound-F test, and ECM regression. The study found a positive relationship between GDP growth and technological innovation in the short and long run...
2024: PloS One
#27
JOURNAL ARTICLE
Yasuyuki Minamiyama, Hideaki Takeda, Masaharu Hayashi, Makoto Asaoka, Kazutsuna Yamaji
In recent years, with the trend of open science, there have been many efforts to share research data on the internet. To promote research data sharing, data curation is essential to make the data interpretable and reusable. In research fields such as life sciences, earth sciences, and social sciences, tasks and procedures have been already developed to implement efficient data curation to meet the needs and customs of individual research fields. However, not only data sharing within research fields but also interdisciplinary data sharing is required to promote open science...
2024: PloS One
#28
JOURNAL ARTICLE
Maxy B De Los Santos, Steev Loyola, Erika S Perez-Velez, Rocio Del Pilar Santos, Ivonne Melissa Ramírez, Hugo O Valdivia
BACKGROUND: Accuracy of molecular tools for the identification of parasites that cause human cutaneous leishmaniasis (CL) could largely depend on the sampling method. Non-invasive or less-invasive sampling methods such as filter paper imprints and cotton swabs are preferred over punch biopsies and lancet scrapings for detection methods of Leishmania based on polymerase chain reaction (PCR) because they are painless, simple, and inexpensive, and of benefit to military and civilian patients to ensure timely treatment...
April 2024: PLoS Neglected Tropical Diseases
#29
JOURNAL ARTICLE
Alemu Degu Ayele, Bekalu Getnet Kassa, Gedefaye Nibret Mihretie, Habtamu Gebrehana Belay, Dagne Addisu Sewyew, Abenezer Melkie Semahegn, Enyew Dagnew Yehuala, Gebrehiwot Ayalew Tiruneh, Lebeza Alemu Tenaw, Abrham Debeb Sendekie, Adanech Getie Teffera, Eden Workneh Aychew, Yismaw Yimam Belachew, Tewachew Muche Liyeh, Mulugeta Dile Worke
BACKGROUND: Despite policy initiatives and strategic measures highly focused on preventing mother-to-child transmission through the implementation of the Option B+ program, adherence to the treatment is still challenging. The level of adherence and determinants of Option B+ program utilization reported by different studies were highly inconsistent in Ethiopia. Hence, this systematic review and meta-analysis aimed to estimate the pooled prevalence of adherence to the Option B+ program and its predictors among HIV-positive women in Ethiopia...
2024: PloS One
#30
JOURNAL ARTICLE
Mina S Fanous, Julia E de la Cruz, Olugbenga S Michael, Jeremiah M Afolabi, Ravi Kumar, Adebowale Adebiyi
Sepsis is the most frequent risk factor for acute kidney injury (AKI) in critically ill infants. Sepsis-induced dysregulation of kidney microcirculation in newborns is unresolved. The objective of this study was to use the translational swine model to evaluate changes in kidney function during the early phase of sepsis in newborns and the impact of fluid plus norepinephrine (NE) resuscitation. Newborn pigs (3-7-day-old) were allocated randomly to three groups: 1) Sham, 2) Sepsis (cecal ligation and puncture; CLP) without subsequent resuscitation, and 3) Sepsis with Lactated Ringer plus NE resuscitation...
April 23, 2024: Shock
#31
JOURNAL ARTICLE
Andrea Caycedo Lozano, Alejandro Serrano, Diana Salazar, Juliana Vanessa Rincón, Mónica Pardo Bayona
Introduction: Glaucoma is a leading cause of irreversible blindness. It is a prevalent disease worldwide, affecting ∼70 million people and expected to reach up to 112 million by 2040. Purpose: The aim of this study is to describe the implementation and initial experience of a telemedicine program to monitor glaucoma and glaucoma suspect patients in a large, integrated health care system during the COVID-19 pandemic. Methods: A retrospective chart review of established glaucoma or glaucoma suspect patients who participated in a telemedicine evaluation at the ophthalmic center of a large, Colombian health care system between June 2020 and April 2023 was conducted...
April 25, 2024: Telemedicine Journal and E-health
#32
JOURNAL ARTICLE
Catherine Johnson, Autumn Chidester, Divya Chandramohan, Hueylie Lin, Nhat Minh Ho, Anna Taranova, Ank E Nijhawan, Susan Kools, Karen Ingersoll, Rebecca Dillingham, Barbara S Taylor
Youth with HIV (YWH) face challenges in achieving viral suppression, particularly in the Southern United States, and welcome novel interventions responsive to community needs. The Theory of Planned Behavior (TPB) describes factors that influence behavior change, and the Positive Youth Development (PYD) supports youth-focused program design. We applied TPB and PYD to explore factors supporting care engagement and challenges for YWH in South Texas. We conducted 14 semi-structured interviews with YWH and 7 focus groups with 26 stakeholders informed by TPB, PYD, and themes from a youth advisory board (YAB)...
April 25, 2024: AIDS Patient Care and STDs
#33
JOURNAL ARTICLE
Yihong Zhao, Martin P Paulus, Susan F Tapert, Kara S Bagot, R Todd Constable, H Klar Yaggi, Nancy S Redeker, Marc N Potenza
BACKGROUND AND AIMS: The precise roles of screen media activity (SMA) and sleep problems in relation to child/adolescent psychopathology remain ambiguous. We investigated temporal relationships among sleep problems, SMA, and psychopathology and potential involvement of thalamus-prefrontal-cortex (PFC)-brainstem structural covariation. METHODS: This study utilized data from the Adolescent Brain Cognitive Development study (n = 4,641 ages 9-12) at baseline, Year1, and Year2 follow-up...
April 24, 2024: Journal of Behavioral Addictions
#34
JOURNAL ARTICLE
Ramón L Panadés-Barrueta, Denis Duflot, Juan Soto, Emilio Martínez-Núñez, Daniel Peláez
We present the detailed topographical characterisation (stationary points and minimum energy paths connecting them) of the full dimensional (81D) intermolecular potential energy surface associated with the non-covalent interactions between the NO2 radical and the pyrene (C16 H10 ) molecule. The whole procedure is (quasi) fully automated. We have used our recent algorithm vdW-TSSCDS as implemented on the freely-available AutoMekin software package. To this end, a series of inexpensive classical trajectories using forces from a low-level (semi-empirical) theory are used to sample the configuration space of the system in the search for candidates to first order saddle points...
April 25, 2024: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
#35
JOURNAL ARTICLE
Ian Kwok, Emily Gardiner Lattie, Dershung Yang, Amanda Summers, Paul Cotten, Caroline Alina Leong, Judith Tedlie Moskowitz
BACKGROUND: Alzheimer disease is a degenerative neurological condition that requires long-term care. The cost of these responsibilities is often borne by informal caregivers, who experience an elevated risk of negative physical and psychological outcomes. Previously, we designed a positive emotion regulation intervention that was shown to improve well-being among dementia caregivers when delivered through one-on-one videoconferencing lessons with a trained facilitator. However, the format required significant resources in terms of logistics and facilitator time...
April 25, 2024: JMIR Formative Research
#36
JOURNAL ARTICLE
Adaptive bio-behavioral control: A pilot analysis of human-machine co-adaptation in type 1 diabetes.
Patricio Colmegna, Ryan McFadden, Chiara Fabris, Benjamin Lobo, Ralf Nass, Mary Clancy-Oliveri, Sue A Brown, Boris P Kovatchev
BACKGROUND: While it is well recognized that an automated insulin delivery (AID) algorithm should adapt to changes in physiology, it is less understood that the individual would also have to adapt to the AID system. The adaptive bio-behavioral control (ABC) method presented here attempts to compensate for this deficiency by including AID into an information cloud-based ecosystem. METHODS: The Web Information Tool (WIT) implements the ABC concept via: (1) A Physiological Adaptation Module (PAM) that tracks metabolic changes and adapts AID parameters accordingly, and (2) a Behavioral Adaptation Module (BAM) that provides information feedback...
April 25, 2024: Diabetes Technology & Therapeutics
#37
JOURNAL ARTICLE
Si Yinn Lu, Sungwon Yoon, Wan Qi Yee, Nerice Heng Wen Ngiam, Kennedy Yao Yi Ng, Lian Leng Low
BACKGROUND: Older adults worldwide experienced heightened risks of depression, anxiety, loneliness, and poor mental well-being during the COVID-19 pandemic. During this period, digital technology emerged as a means to mitigate social isolation and enhance social connectedness among older adults. However, older adults' behaviors and attitudes toward the adoption and use of digital technology are heterogeneous and shaped by factors such as age, income, and education. Few empirical studies have examined how older adults experiencing social and economic disadvantages perceive the learning of digital tools...
April 25, 2024: JMIR aging
#38
JOURNAL ARTICLE
Patrice D Tremoulet, Andrea F Lobo, Christina A Simmons, Ganesh Baliga, Matthew Brady
BACKGROUND: The United States is experiencing a direct support professional (DSP) crisis, with demand far exceeding supply. Although generating documentation is a critical responsibility, it is one of the most wearisome aspects of DSPs' jobs. Technology that enables DSPs to log informal time-stamped notes throughout their shift could help reduce the burden of end-of-shift documentation and increase job satisfaction, which in turn could improve the quality of life of the individuals with intellectual and developmental disabilities (IDDs) whom DSPs support...
April 25, 2024: JMIR Human Factors
#39
JOURNAL ARTICLE
Ruth E Hogg, Sobha Sivaprasad, Robin Wickens, Sean O'Connor, Eleanor Gidman, Elizabeth Ward, Charlene Treanor, Tunde Peto, Ben J L Burton, Paul Knox, Andrew J Lotery, Michael Donnelly, Chris A Rogers, Barnaby C Reeves
IMPORTANCE: Most neovascular age-related macular degeneration (nAMD) treatments involve long-term follow-up of disease activity. Home-monitoring would reduce the burden on patients and their caregivers and release clinic capacity. OBJECTIVE: To evaluate 3 vision home-monitoring tests for patients to use to detect active nAMD compared with diagnosing active nAMD at hospital follow-up during the after-treatment monitoring phase. DESIGN, SETTING, AND PARTICIPANTS: This was a diagnostic test accuracy study wherein the reference standard was detection of active nAMD by an ophthalmologist at hospital follow-up...
April 25, 2024: JAMA Ophthalmology
#40
JOURNAL ARTICLE
Oliverio Stefania, Ferger Marie-Caroline, Yegles Michel
Total Blood Carbon Monoxide (TBCO) showed promising results in improving accuracy of CO determinations in blood and presenting better stability to different storage conditions. Therefore, it was proposed as alternative biomarker to carboxyhemoglobin (COHb) for CO poisoning diagnosis. However, given that current interpretation reference values exist for COHb only, it is difficult to implement TBCO analysis in routine. Therefore, we aimed at determining TBCO reference values for postmortem CO poisoning cases...
April 24, 2024: Journal of Analytical Toxicology
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