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https://www.readbyqxmd.com/read/29141362/-evaluation-of-the-psychological-feature-and-quality-of-life-in-outpatients-with-somatic-symptoms-disorder-in-a-general-hospital
#1
F H Cui, N N Xiong, X Hong, Y P Duan, J Wei
Objective: To explore the psychological features and quality of life in outpatients with somatic symptoms disorder in a general hospital. Methods: This cross-sectional study was conducted from 2014-05 to 2015-06. Patients diagnosed with major depressive disorder (MDD) and somatic symptoms disorder (SSD) were recruited from psychological outpatient department, and patients with peptic ulcer (PU) / reflux esophagitis (RE) were recruited from Gastroenterology. Depression scale of the patient health questionnaire (PHQ-9), Generalized Anxiety Disorder 7-item scale (GAD-7), Toronto Alexithymia scale (TAS), 12-item Short Form Health Survey (SF-12), items from Somatoform Disorder Screening Questionnaire were employed to evaluate the severity of depression, anxiety, alexithymia, quality of life, health care use and subjective feelings...
November 7, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29141191/microbial-lipids-and-added-value-metabolites-production-by-yarrowia-lipolytica-from-pork-lard
#2
Marlene Lopes, Andreia S Gomes, Carla M Silva, Isabel Belo
Yarrowia lipolytica is a suitable microbial platform to convert low-value hydrophobic substrates into microbial oils and other important metabolites. In this work, this yeast species was used to simultaneously synthetize ex novo lipids and produce citric acid and lipase from animal fat (pork lard) adding higher value to the low-cost fatty substrate. The effect of pH, lard concentration, arabic gum concentration and oxygen mass transfer rate (OTR) on lipids accumulation on Y. lipolytica batch cultures was assessed by an experimental design based on Taguchi method...
November 12, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/29141140/n-heterocyclic-carbene-self-assembled-monolayers-on-gold-as-surface-plasmon-resonance-biosensors
#3
Zhijun Li, Kim A Munro, Iraklii I Ebralidze, Mina R Narouz, J Daniel Padmos, Hongxia Hao, Cathleen M Crudden, J Hugh Horton
Surface plasmon resonance (SPR)-based biosensing is a powerful tool to study the recognition processes between biomole-cules in real-time without need for labels. The use of thiol chemistry is a critical component in surface functionalization of various SPR biosensor surfaces on gold. However, its use is hampered by the high propensity for oxidation of the gold-thiol linkage even in ambient atmosphere, resulting in a short lifetime of SPR sensor chips unless strict precautions are taken. Herein, we describe an approach to overcome this limitation by employing highly robust self-assembled monolayers (SAMs) of alkylated N-heterocyclic carbenes (NHCs) on gold...
November 15, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29141069/a-novel-multi-targeting-approach-to-treating-hair-loss-using-standardized-nutraceuticals
#4
Patricia K Farris, Nicole Rogers, Amy McMichael, Sophia Kogan
<p>Hair loss is a complicated problem that causes significant concern for those who are affected. Patients seeking medical treatment have limited options that include topical minoxidil and oral finasteride. While these treatments are backed by long term clinical use and research outcomes, many patients find topical minoxidil difficult to incorporate into their daily routine and some are concerned with the side effects associated with finasteride. In the office setting, patients may be treated with more invasive procedures such as platelet-rich plasma injections (PRP) and hair transplantation, treatments that often must be repeated and can lead to a costly investment...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29140871/hiv-prevalence-and-associated-risk-factors-among-men-who-have-sex-with-men-in-dar-es-salaam-tanzania
#5
Elia John Mmbaga, Kåre Moen, Germana Henry Leyna, Rose Mpembeni, Melkizedeck Thomas Leshabari
INTRODUCTION: Limited studies and differential risk behaviours among men who have sex with men(MSM) in Africa calls for population specific studies. We present results from the largest integrated bio-behavioural survey among MSM in Africa to inform programming. METHODS: This was a cross-sectional study utilizing respondent driven sampling to recruit MSM aged 18 and above. Data on socio-demographic characteristics and HIV-related risks were collected and all participants were tested for HIV, Herpes Simplex Virus Type-2 (HSV-2), Hepatitis-B Virus (HBV) and Syphilis...
November 13, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29140679/a-green-approach-to-improving-the-strength-and-flame-retardancy-of-poly-vinyl-alcohol-clay-aerogels-incorporating-bio-based-gelatin
#6
Yu-Tao Wang, Hai-Bo Zhao, Kimberly C Degracia, Lin-Xuan Han, Hua Sun, Mingze Sun, Yu-Zhong Wang, David A Schiraldi
Bio-based gelatins were used to improve the compressive and flammability properties poly(vinyl alcohol)/montmorillonite (PVA/MMT) aerogels, fabricated using a simple and environmentally-friendly freeze-drying method. Due to the excellent compatibility and strong interfacial adhesion between PVA and gelatin, the compressive moduli of aerogels were enhanced dramatically with the incorporation of gelatin. PVA/MMT/porcine gelatin aerogels exhibit compressive modulus values as much as 12.4 MPa, nearly 300% that of the control PVA/MMT aerogel...
November 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29140566/mesenchymal-stem-cell-preparation-and-transfection-free-ferumoxytol-labeling-for-mri-cell-tracking
#7
Li Liu, Chien Ho
Mesenchymal stem cells (MSCs) are multipotent cells and are the most widely studied cell type for stem cell therapies. In vivo cell tracking of MSCs labeled with an FDA-approved superparamagnetic iron-oxide (SPIO) particle by magnetic resonance imaging (MRI) provides essential information, e.g., MSC engraftment, survival, and fate, thus improving cell therapy accuracy. However, current methodology for labeling MSCs with Ferumoxytol (Feraheme(®) ), the only FDA-approved SPIO particle, needs transfection agents...
November 15, 2017: Current Protocols in Stem Cell Biology
https://www.readbyqxmd.com/read/29140368/in-vitro-bioactivity-test-of-real-dental-implants-according-to-iso-23317
#8
Martina Kolafová, Jan Šťovíček, Jakub Strnad, Josef Zemek, Jiři Dybal
PURPOSE: The goal of this study was to compare the in vitro bioactivity in simulated body fluid (SBF) of commercially available dental implants. MATERIALS AND METHODS: Bioactivity, according to ISO 23317, of commercially available dental implants with various surface modifications (BIO-surface, SLA, SLActive, TiUnite, and OsseoSpeed) was tested in SBF for 1 and 3 weeks. Surface characterizations, especially calcium and phosphorus surface content before and after the immersion in SBF, were performed...
November 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29140316/hybrid-system-for-in-vivo-epifluorescence-and-4d-optoacoustic-imaging
#9
Zhenyue Chen, Xosé Luis Deán-Ben, Sven Gottschalk, Daniel Razansky
Epifluorescence imaging is widely used in cell and molecular biology due to its excellent sensitivity, contrast, and ease of implementation. Optoacoustic imaging has been shown to deliver a highly complementary and unique set of capabilities for biological discovery, such as high spatial resolution in noninvasive deep tissue observations, fast volumetric imaging capacity, and spectrally enriched contrast. In this Letter, we report on a hybrid system combining planar fluorescence and real-time volumetric four-dimensional optoacoustic imaging by means of a fiberscope integrated within a handheld hemispherical ultrasound detection array...
November 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29140077/superior-robust-ultra-thin-single-crystalline-silicon-carbide-membrane-as-a-versatile-platform-for-biological-applications
#10
Tuan-Khoa Nguyen, Hoang-Phuong Phan, Harshad Kamble, Raja Vadivelu, Toan Khac Dinh, Alan Iacopi, Glenn Walker, Leonie Hold, Nam-Trung Nguyen, Dzung Viet Dao
Micro-machined membranes are promising platforms for cell culture thanks to their miniaturization and integration capabilities. Possessing chemical inertness, bio compatibility and integration, silicon carbide (SiC) membranes have attracted great interest towards biological applications. In this paper, we present the batch fabrication, mechanical characterizations, and cell culture demonstration of robust ultra-thin epitaxial deposited SiC membranes. The as-fabricated ultra-thin SiC membranes, with an ultra-high aspect ratio (length/thickness) of up to 20,000, possess high a fracture strength up to 2...
November 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29139285/subradiant-dipolar-interactions-in-plasmonic-nanoring-resonator-array-for-integrated-label-free-biosensing
#11
Yuzhang Liang, Hui Zhang, Wenqi Zhu, Amit Agrawal, Henri J Lezec, Lixia Li, Wei Peng, Yi Zou, Yan-Qing Lu, Ting Xu
With the development of advanced nanofabrication technologies over the last decade, plasmonic nanostructures have attracted wide attention for their potential in label-free biosensing applications. However, the sensing performance of nanostructured plasmonic sensors is primarily limited by the broad-linewidth features with low peak-to-dip signal ratio in the extinction spectra that result from strong radiative damping. Here, we propose and systematically investigate the in-plane and out-of-plane dipolar interactions in an array of plasmonic nanoring resonators that are from the spatial combination of classic nanohole and nanodisk structures...
November 15, 2017: ACS Sensors
https://www.readbyqxmd.com/read/29138908/amine-modified-magnetic-iron-oxide-nanoparticle-as-a-promising-carrier-for-application-in-bio-self-healing-concrete
#12
Mostafa Seifan, Alireza Ebrahiminezhad, Younes Ghasemi, Ali Khajeh Samani, Aydin Berenjian
Self-healing mechanisms are a promising solution to address the concrete cracking issue. Among the investigated self-healing strategies, the biotechnological approach is distinguished itself by inducing the most compatible material with concrete composition. In this method, the potent bacteria and nutrients are incorporated into the concrete matrix. Once cracking occurs, the bacteria will be activated, and the induced CaCO3 crystals will seal the concrete cracks. However, the effectiveness of a bio self-healing concrete strictly depends on the viability of bacteria...
November 14, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29138806/effect-of-bis-hydroxymethyl-alkanoate-curcuminoid-derivative-mth-3-on-cell-cycle-arrest-apoptotic-and-autophagic-pathway-in-triple-negative-breast-adenocarcinoma-mda-mb-231-cells-an-in-vitro-study
#13
Ling-Chu Chang, Min-Tsang Hsieh, Jai-Sing Yang, Chi-Cheng Lu, Fuu-Jen Tsai, Je-Wei Tsao, Yu-Jen Chiu, Sheng-Chu Kuo, Kuo-Hsiung Lee
Curcumin has been shown to exert potential antitumor activity in vitro and in vivo involved in multiple signaling pathways. However, the application of curcumin is still limited because of its poor hydrophilicity and low bio-availability. In the present study, we investigated the therapeutic effects of a novel and water soluble bis(hydroxymethyl) alkanoate curcuminoid derivative, MTH-3, on human breast adenocarcinoma MDA-MB-231 cells. This study investigated the effect of MTH-3 on cell viability, cell cycle and induction of autophagy and apoptosis in MDA-MB-231 cells...
November 14, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/29138654/syphilis-and-hiv-infections-among-pregnant-women-attending-antenatal-clinics-in-republic-of-congo
#14
Roch Fabien Niama, Nadia Claricelle Loukabou Bongolo, Edith Sophie Bayonne Kombo, Ruth Yengo, Pembe Issamou Mayengue, Etoka-Beka Mandingha Kosso, Igor Louzolo, Lucette Macosso, Ghislain Dzeret, Angélie Serge Patrick Dzabatou Babeaux, Marie-Francke Puruehnce, Henri Joseph Parra
Introduction: HIV and syphilis during pregnancy remain a public health concern especially in developing countries. Pregnant women attending antenatal clinics sites for the first time between September and December 2011 and who accepted to participate in the study were enrolled. The objective was to estimate the syphilis and HIV infection rate in this population. Methods: A study was conducted in 44 selected ANCs from 12 departments (5 urban and 7 rural). Pregnant women who accepted to participate in the study, attending selected sentinel ANCs sites for the first time between September and December 2011 were enrolled...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29138434/generating-localized-plasmonic-fields-on-an-integrated-photonic-platform-using-tapered-couplers-for-biosensing-applications
#15
Gurpreet Singh, Renzhe Bi, U S Dinish, Malini Olivo
A theoretical design and analysis of a tapered-coupler structure on a silicon nitride integrated-photonic platform for coupling optical energy from a dielectric waveguide to a plasmonic tip is presented. The proposed design can be considered as a hybrid photonic-plasmonic structure that generally supports hybrid symmetric and asymmetric modes. Along the taper, one of the hybrid modes approaches the cut-off, while the other approaches the short-range surface plasmon mode that generates localized fields. Potential use of the proposed novel tapered-coupler plasmonic structure for highly sensitive biosensing applications using surface enhanced Raman scattering (SERS) and metal enhanced fluorescence (MEF) techniques is discussed...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29138306/key-metabolites-and-mechanistic-changes-for-salt-tolerance-in-an-experimentally-evolved-sulfate-reducing-bacterium-desulfovibrio-vulgaris
#16
Aifen Zhou, Rebecca Lau, Richard Baran, Jincai Ma, Frederick von Netzer, Weiling Shi, Drew Gorman-Lewis, Megan L Kempher, Zhili He, Yujia Qin, Zhou Shi, Grant M Zane, Liyou Wu, Benjamin P Bowen, Trent R Northen, Kristina L Hillesland, David A Stahl, Judy D Wall, Adam P Arkin, Jizhong Zhou
Rapid genetic and phenotypic adaptation of the sulfate-reducing bacterium Desulfovibrio vulgaris Hildenborough to salt stress was observed during experimental evolution. In order to identify key metabolites important for salt tolerance, a clone, ES10-5, which was isolated from population ES10 and allowed to experimentally evolve under salt stress for 5,000 generations, was analyzed and compared to clone ES9-11, which was isolated from population ES9 and had evolved under the same conditions for 1,200 generations...
November 14, 2017: MBio
https://www.readbyqxmd.com/read/29137930/mitigating-external-and-internal-cathode-fouling-using-a-polymer-bonded-separator-in-microbial-fuel-cells
#17
Wulin Yang, Ruggero Rossi, Yushi Tian, Kyoung-Yeol Kim, Bruce E Logan
Microbial fuel cell (MFC) cathodes rapidly foul when treating domestic wastewater, substantially reducing power production over time. Here a wipe separator was chemically bonded to an activated carbon air cathode using polyvinylidene fluoride (PVDF) to mitigate cathode fouling and extend cathode performance over time. MFCs with separator-bonded cathodes produced a maximum power density of 190 ± 30 mW m(-2) after 2 months of operation using domestic wastewater, which was ∼220% higher than controls (60 ± 50 mW m(-2)) with separators that were not chemically bonded to the cathode...
November 4, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29137909/use-of-expired-air-carbon-monoxide-testing-in-clinical-tobacco-treatment-settings
#18
REVIEW
Adam O Goldstein, Stephanie P Gans, Carol Ripley-Moffitt, Chris Kotsen, Matthew Bars
Carbon Monoxide (CO) testing is considered an easy, non-invasive, and objective contribution to the assessment of smoking behavior, as CO is rapidly absorbed into the blood stream when lit cigarettes or cigars are inhaled. CO testing is a medically important, billable outpatient service that can contribute to sustainability of face-to-face tobacco use treatment services by clinicians. This article reviews research on the clinical use of CO testing to provide bio-medical feedback in assessing smoking behavior, on educating smokers on tobacco health effects, on assisting with treatment planning, and as a motivational tool to encourage people to become tobacco free...
November 11, 2017: Chest
https://www.readbyqxmd.com/read/29137388/rapid-and-accurate-detection-of-kras-mutations-in-colorectal-cancers-using-the-isothermal-based-optical-sensor-for-companion-diagnostics
#19
Choong Eun Jin, Seung-Seop Yeom, Bonhan Koo, Tae Yoon Lee, Jeong Hoon Lee, Yong Shin, Seok-Byung Lim
Although KRAS mutational status testing is becoming a companion diagnostic tool for managing patients with colorectal cancer (CRC), there are still several difficulties when analyzing KRAS mutations using the existing assays, particularly with regard to low sensitivity, its time-consuming, and the need for large instruments. We developed a rapid, sensitive, and specific mutation detection assay based on the bio-photonic sensor termed ISAD (isothermal solid-phase amplification/detection), and used it to analyze KRAS gene mutations in human clinical samples...
October 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/29137291/the-clinicopathological-significance-and-prognostic-value-of-emmprin-overexpression-in-cancers-evidence-from-39-cohort-studies
#20
Hengwei Fan, Wanwan Yi, Chenxing Wang, Jisheng Wang
Extracellular matrix metalloproteinase inducer (EMMPRIN) has been reported to be associated with tumor formation and invasion in many studies. However, the clinicopathological significance and prognosis of EMMPRIN in cancer patients remains inconclusive. Therefore, we conducted a meta-analysis to assess the predictive potential of EMMPRIN in various cancers. By searching Pubmed, Cochrane library database and web of science comprehensively, 39studies with 5739 cases were included in our meta-analysis. The results indicated that EMMPRIN overexpression was significantly associated with poor outcome of cancers (HR=2...
October 10, 2017: Oncotarget
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