keyword
MENU ▼
Read by QxMD icon Read
search

bio

keyword
https://www.readbyqxmd.com/read/29793144/structural-confirmation-and-spectroscopic-study-of-a-biomolecule-norepinephrine
#1
T Yadav, V Mukherjee
The present work deals with the conformational and vibrational spectroscopic study of an important bio-molecule named norepinephrine in gas phase. The FTIR and FTRaman spectrum of norepinephrine in amorphous form were recorded in wavenumber range 4000-400 cm-1 and 4000-50 cm-1 respectively. We have investigated twenty-seven stable conformational structures of norepinephrine molecule. All the calculations have been done using Density Functional Theory with exchange functional B3LYP incorporated with the 6-31++G(d, p) basis set...
May 21, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29793109/17%C3%AE-estradiol-as-precursors-of-cl-br-dbps-in-the-disinfection-process-of-different-water-samples
#2
Yanan Shao, Zihan Pan, Chuan Rong, Yinghui Wang, Hongxiang Zhu, Yuanyuan Zhang, Kefu Yu
During chlorine disinfection process, reactions between the disinfectant and 17β-estradiol (E2) lead to the formation of halogenated disinfection byproducts (DBPs) which can be a risk to both ecosystem and human health. The degradation and transformation products of E2 in sodium hypochlorite (NaClO) disinfection processes of different water samples were investigated. The reaction kinetics research showed that the degradation rates of E2 were considerably dependent on the initial pH value and the types of water samples...
May 21, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29792967/validated-reverse-phase-hplc-diode-array-method-for-the-quantification-of-intact-bevacizumab-infliximab-and-trastuzumab-for-long-term-stability-study
#3
Antonio Martínez-Ortega, Agustín Herrera, Antonio Salmerón-García, José Cabeza, Luis Cuadros-Rodríguez, Natalia Navas
The aim of the present study was to develop suitable and reliable method for quantification three of the most worldwide used therapeutic monoclonal antibodies (mAbs) -bevazizumab (BVZ), infliximab (INF) and trastuzumab (TTZ)- to be used in long-term stability studies. Reverse phase (RP) was selected by its greater sensibility and reproducibility comparing with other chromatographic modes. Then a high performance liquid chromatography with diode array detection (RP)HPLC/DAD method was checked. Since the three mAbs represent the active ingredient in the medicines in which they are formulated, the selected method was validated for each one in accordance with the International Conference on Harmonization (ICH) guidelines for pharmaceuticals for human use...
May 21, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29792956/development-of-photo-modified-starch-kefiran-tio-2-bio-nanocomposite-as-an-environmentally-friendly-food-packaging-material
#4
Vahid Goudarzi, Iman Shahabi-Ghahfarrokhi
This paper reports on an experiment in which starch/kefiran/TiO2 (SKT)-based bio-nanocomposite films were developed and modified by photo-chemical reaction. In so doing, film-forming solutions were exposed to ultraviolet A (UV-A) for different times (1, 6, and 12 h). The obtained results indicated that increasing UV-A exposure time brought about an increase (≈14.9%) in the tensile strength of bio-nanocomposites. However, elongation at break and Young's modulus of irradiated film specimen decreased (≈32%, ≈12%, respectively) by increasing UV-A exposure time, and the moisture-sensitive parameters of specimen decreased using UV-A irradiation...
May 21, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29792943/the-development-of-a-screening-protocol-for-salmonella-spp-and-enteropathogenic-yersinia-spp-in-samples-from-wild-boar-sus-scrofa-also-generating-mlva-data-for-y-enterocolitica-and-y-pseudotuberculosis
#5
Axel Sannö, Magdalena Jacobson, Sandra Sterner, Susanne Thisted-Lambertz, Anna Aspán
Salmonellosis and yersiniosis are notifiable human diseases that are commonly associated with contaminated food. Domestic pigs as well as wild boars and other wild-life have been identified as reservoirs of these bacteria. Methods for cultivation and molecular epidemiological investigations of Salmonella spp. are well established, however, cultivation of enteropathogenic Yersinia spp. is time- consuming and the commonly used method for molecular epidemiological investigations, pulsed-field gel electrophoresis, lack in discriminatory power...
May 21, 2018: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29792199/nanoparticle-delivery-of-grape-seed-derived-proanthocyanidins-to-airway-epithelial-cells-dampens-oxidative-stress-and-inflammation
#6
S Castellani, A Trapani, A Spagnoletta, L di Toma, T Magrone, S Di Gioia, D Mandracchia, G Trapani, E Jirillo, M Conese
BACKGROUND: Chronic respiratory diseases, whose one of the hallmarks is oxidative stress, are still incurable and need novel therapeutic tools and pharmaceutical agents. The phenolic compounds contained in grape are endowed with well-recognized anti-oxidant, anti-inflammatory, anti-cancer, and anti-aging activities. Considering that natural anti-oxidants, such as proanthocyanidins, have poor water solubility and oral bioavailability, we have developed a drug delivery system based on solid lipid nanoparticles (SLN), apt to encapsulate grape seed extract (GSE), containing proanthocyanidins...
May 23, 2018: Journal of Translational Medicine
https://www.readbyqxmd.com/read/29791569/solubility-porosity-and-fluid-uptake-of-calcium-silicate-based-cements
#7
Fernanda Ferrari Esteves Torres, Juliane Maria Guerreiro-Tanomaru, Roberta Bosso-Martelo, Gisselle Moraima Chavez-Andrade, Mario Tanomaru Filho
OBJECTIVE: To evaluate the absorption/fluid uptake, solubility and porosity of White mineral trioxide aggregate (MTA) Angelus, Biodentine (BIO), and zinc oxide-eugenol (ZOE). MATERIAL AND METHODS: Solubility was evaluated after immersion in distilled water for 7 and 30 days. Porosity was evaluated using digital inverted microscope, scanning electron microscope (SEM) and micro-computed tomography (micro-CT). For the fluid uptake test, specimens were immersed in Hank's balanced salt solution (HBSS) for 1, 7, 14 and 28 days...
2018: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29791235/long-term-planetary-habitability-and-the-carbonate-silicate-cycle
#8
Andrew J Rushby, Martin Johnson, Benjamin J W Mills, Andrew J Watson, Mark W Claire
The potential habitability of an exoplanet is traditionally assessed by determining whether its orbit falls within the circumstellar "habitable zone" of its star, defined as the distance at which water could be liquid on the surface of a planet (Kopparapu et al., 2013 ). Traditionally, these limits are determined by radiative-convective climate models, which are used to predict surface temperatures at user-specified levels of greenhouse gases. This approach ignores the vital question of the (bio)geochemical plausibility of the proposed chemical abundances...
May 2018: Astrobiology
https://www.readbyqxmd.com/read/29791080/one-step-lignocellulose-fractionation-using-2-5-furandicarboxylic-acid-as-biogenic-and-recyclable-catalyst
#9
Dennis Weidener, Holger Klose, Walter Leitner, Ulrich Schurr, Björn Usadel, Pablo Domínguez de María, Philipp Michael Grande
To develop novel biorefinery concepts, the use of bio-based catalysts and solvents must be aligned with the Green Chemistry principles. In this context biogenic 2,5-furandicarboxylic acid (FDCA) is a very promising, yet underused molecule with high potential application as acid catalyst combining feasibility and sustainability with an efficient and straightforward recovery. In this work, FDCA was evaluated as catalyst in the recently developed OrganoCat pretreatment, a biphasic lignocellulose fractionation system...
May 23, 2018: ChemSusChem
https://www.readbyqxmd.com/read/29790875/visible-light-induced-electropolymerization-of-suspended-hydrogel-bioscaffolds-in-a-microfluidic-chip
#10
Pan Li, Haibo Yu, Na Liu, Feifei Wang, Gwo-Bin Lee, Yuechao Wang, Lianqing Liu, Wen Jung Li
The development of microengineered hydrogels co-cultured with cells in vitro could advance in vivo bio-systems in both structural complexity and functional hierarchy, which holds great promise for applications in regenerative tissues or organs, drug discovery and screening, and bio-sensors or bio-actuators. Traditional hydrogel microfabrication technologies such as ultraviolet (UV) laser or multiphoton laser stereolithography and three-dimensional (3D) printing systems have advanced the development of 3D hydrogel micro-structures but need either expensive and complex equipment, or harsh material selection with limited photoinitiators...
May 23, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29790524/alleviating-luminescence-concentration-quenching-in-lanthanide-doped-caf-2-based-nanoparticles-through-na-ion-doping
#11
Bing Xu, Dongyu Li, Zhen Huang, Chunliang Tang, Wenhao Mo, Ying Ma
Luminescence concentration quenching, mainly due to a cross relaxation (CR) process between lanthanide ions (Ln3+), widely occurs in Ln3+ doped luminescent materials, setting a limit in the dopant content of Ln3+ emitters to withhold the brightness. Here, we introduced Na+ ions into the CaF2 host lattice codoped with Nd3+ emitters that alleviates concentration quenching greatly. And we show that the optimal dopant concentration of Nd3+ in colloidal CaF2:Nd nanoparticles increased from 10 to 30 mol%, resulting in an ∼32 times near-infrared (NIR) (1052 nm) brightness under 800 nm laser irradiation...
May 23, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29790480/two-year-clinical-outcome-of-all-comers-treated-with-three-highly-dissimilar-contemporary-coronary-drug-eluting-stents-in-the-randomised-bio-resort-trial
#12
Marlies M Kok, Paolo Zocca, Rosaly A Buiten, Peter W Danse, Carl E Schotborgh, Martijn Scholte, Marc Hartmann, Martin G Stoel, Gert van Houwelingen, Gerard C M Linssen, Carine J M Doggen, Clemens von Birgelen
AIMS: The aim of the study was to evaluate the two-year clinical outcome of all-comer trial participants who were treated with two very different thin-strut biodegradable polymer versus thin-strut durable polymer drug-eluting stents (DES). Prolonged clinical outcome after discontinuation of dual antiplatelet therapy is of particular interest, given the highly dissimilar polymer types, amount, distribution, and degradation speed of both biodegradable polymer DES. METHODS AND RESULTS: The BIO-RESORT trial (NCT01674803) randomly assigned 3,514 patients to treatment with biodegradable polymer SYNERGY everolimus-eluting stents (EES) or Orsiro sirolimus-eluting stents (SES), or durable polymer Resolute Integrity zotarolimus-eluting stents (ZES)...
May 23, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29790010/pectin-and-mucin-enhance-the-bioadhesion-of-drug-loaded-nanofibrillated-cellulose-films
#13
Patrick Laurén, Heli Paukkonen, Tiina Lipiäinen, Yujiao Dong, Timo Oksanen, Heikki Räikkönen, Henrik Ehlers, Päivi Laaksonen, Marjo Yliperttula, Timo Laaksonen
PURPOSE: Bioadhesion is an important property of biological membranes, that can be utilized in pharmaceutical and biomedical applications. In this study, we have fabricated mucoadhesive drug releasing films with bio-based, non-toxic and biodegradable polymers that do not require chemical modifications. METHODS: Nanofibrillar cellulose and anionic type nanofibrillar cellulose were used as film forming materials with known mucoadhesive components mucin, pectin and chitosan as functional bioadhesion enhancers...
May 22, 2018: Pharmaceutical Research
https://www.readbyqxmd.com/read/29789567/precise-control-of-scramble-in-synthetic-haploid-and-diploid-yeast
#14
Bin Jia, Yi Wu, Bing-Zhi Li, Leslie A Mitchell, Hong Liu, Shuo Pan, Juan Wang, Hao-Ran Zhang, Nan Jia, Bo Li, Michael Shen, Ze-Xiong Xie, Duo Liu, Ying-Xiu Cao, Xia Li, Xiao Zhou, Hao Qi, Jef D Boeke, Ying-Jin Yuan
Compatibility between host cells and heterologous pathways is a challenge for constructing organisms with high productivity or gain of function. Designer yeast cells incorporating the Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) system provide a platform for generating genotype diversity. Here we construct a genetic AND gate to enable precise control of the SCRaMbLE method to generate synthetic haploid and diploid yeast with desired phenotypes. The yield of carotenoids is increased to 1...
May 22, 2018: Nature Communications
https://www.readbyqxmd.com/read/29789488/superhydrophobic-natural-and-artificial-surfaces-a-structural-approach
#15
REVIEW
Roxana-Elena Avrămescu, Mihaela Violeta Ghica, Cristina Dinu-Pîrvu, Răzvan Prisada, Lăcrămioara Popa
Since ancient times humans observed animal and plants features and tried to adapt them according to their own needs. Biomimetics represents the foundation of many inventions from various fields: From transportation devices (helicopter, airplane, submarine) and flying techniques, to sports' wear industry (swimming suits, scuba diving gear, Velcro closure system), bullet proof vests made from Kevlar etc. It is true that nature provides numerous noteworthy models (shark skin, spider web, lotus leaves), referring both to the plant and animal kingdom...
May 22, 2018: Materials
https://www.readbyqxmd.com/read/29789349/passive-water-collection-with-the-integument-mechanisms-and-their-biomimetic-potential
#16
REVIEW
Philipp Comanns
Several mechanisms of water acquisition have evolved in animals living in arid habitats to cope with limited water supply. They enable access to water sources such as rain, dew, thermally facilitated condensation on the skin, fog, or moisture from a damp substrate. This Review describes how a significant number of animals - in excess of 39 species from 24 genera - have acquired the ability to passively collect water with their integument. This ability results from chemical and structural properties of the integument, which, in each species, facilitate one or more of six basic mechanisms: increased surface wettability, increased spreading area, transport of water over relatively large distances, accumulation and storage of collected water, condensation, and utilization of gravity...
May 22, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29789071/dynamic-ab-initio-methods-for-vibrational-spectroscopy
#17
Sandra Luber
Our group focuses on the development of computational methods derived from quantum mechanics and their application to a variety of challenging systems ranging from (bio-)molecules over coordination compounds to solar light-driven processes. In this review, we describe our recent activities for accurate calculation of spectroscopic properties. Emphasis is put on forefront methods for vibrational spectroscopy, in particular with respect to condensed phase systems, based on ab initio molecular dynamics. This approach has several advantages compared to standard static approaches and proven to be a highly valuable tool for in-depth analysis of complex systems...
May 30, 2018: Chimia
https://www.readbyqxmd.com/read/29789012/novel-tnf-receptor-1-inhibitors-identified-as-potential-therapeutic-candidates-for-traumatic-brain-injury
#18
Rachel K Rowe, Jordan L Harrison, Hongtao Zhang, Adam D Bachstetter, David P Hesson, Bruce F O'Hara, Mark I Greene, Jonathan Lifshitz
BACKGROUND: Traumatic brain injury (TBI) begins with the application of mechanical force to the head or brain, which initiates systemic and cellular processes that are hallmarks of the disease. The pathological cascade of secondary injury processes, including inflammation, can exacerbate brain injury-induced morbidities and thus represents a plausible target for pharmaceutical therapies. We have pioneered research on post-traumatic sleep, identifying that injury-induced sleep lasting for 6 h in brain-injured mice coincides with increased cortical levels of inflammatory cytokines, including tumor necrosis factor (TNF)...
May 22, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29788801/perioperative-noninvasive-cardiac-output-monitoring-in-parturients-with-singleton-and-twin-pregnancies-undergoing-caesarean-section-under-spinal-anesthesia-with-prophylactic-phenylephrine-drip-a-prospective-observational-cohort-study
#19
S Orbach-Zinger, E Razinsky, I Bizman, S Firman, R Gat, A Davis, E Ashwal, A Shmueli, M Vaturi, R Gabbay-Benziv, L A Eidelman
INTRODUCTION: Spinal anesthesia is considered the gold standard anesthetic technique for cesarean deliveries (CD) but is associated with a high rate of hypotension. The recent international consensus recommends continuous prophylactic phenylephrine infusion (PPI) administered throughout CD to prevent hypotension. However little information is available on the hemodynamic profiles of women with twin pregnancies as compared to singleton pregnancies perioperatively. Therefore, in this study we aim we compare maternal hemodynamic changes both intraoperatively and postoperatively with the use of the NICAS bio impendence monitor in healthy singleton versus twin parturients undergoing CD deliveries with spinal anesthesia with PPI...
May 22, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29787950/macroporous-silica-nanoparticles-for-delivering-bcl2-function-converting-peptide-to-treat-multidrug-resistant-cancer-cells
#20
Weixia Xu, Pengjin Ge, Boning Niu, Xiaokun Zhang, Jie Liu, Jingjing Xie
The abundance of B cell lymphoma gene 2 (Bcl-2) is closely correlated with the resistance of cancer cells to chemotherapeutic agents, and a peptide derived from orphan nuclear receptor Nur77 can convert Bcl-2 from a protector to a killer of cancer cells. However, successful application of the Bcl-2-converting peptide to treat drug-resistant cancer cells depends on an efficient delivery carrier. Mesoporous silica nanoparticles (MSNs) have been extensively studied as promising candidates for small molecule drug delivery...
May 15, 2018: Journal of Colloid and Interface Science
keyword
keyword
38237
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"