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https://www.readbyqxmd.com/read/29783121/the-influence-of-nail-blocking-conditions-in-cattle-femoral-fractures
#1
Leopoldo A Paolucci, Estevam B Las Casas, Rafael R Faleiros, Cahuê F R Paz, Sergio S Rocha Junior
BACKGROUND: To investigate the effect of different fixation strategies of the intramedullary interlocking nail (IIN) on the mechanical behavior of a polymeric implant applied for femoral fracture fixation in calves, and to evaluate the performance of a glass fiber-reinforced polymer applied in a bovine femoral fracture reduction system, five Holstein male animals with a mean weight (±SD) of 62.8 ± 20.4 kg and aged 74 ± 15 were used to generate biomechanical parameters for this study...
May 7, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29782242/case-254-posttraumatic-migrating-fat-embolus-causing-fat-emboli-syndrome
#2
Sébastien Molière, Stéphane Kremer, Guillaume Bierry
History An otherwise healthy 18-year-old man was admitted to the emergency department with a closed displaced fracture of the left femoral shaft ( Fig 1 ) after a high-velocity motorbike accident. At admission, other physical examination findings were unremarkable. Initial unenhanced and contrast material-enhanced (120 mL of Iomeron 400; Bracco Imaging, Milan, Italy) computed tomography (CT) was performed in the arterial and venous phases from the head to the knees. No abnormalities were noted in the brain or chest at initial CT...
June 2018: Radiology
https://www.readbyqxmd.com/read/29781308/a-randomised-comparison-of-efficacy-and-safety-of-intralesional-triamcinolone-injection-and-clobetasol-propionate-ointment-for-psoriatic-nails
#3
Einapak Boontaveeyuwat, Narumol Silpa-Archa, Nasuda Danchaivichit, Chanisada Wongpraparut
BACKGROUND: Even though the traditional therapy for nail psoriasis has been used for decades, no randomised, controlled trial of such treatment has been conducted to date. OBJECTIVE: To evaluate the efficacy and safety of intralesional triamcinolone injections compared with 0.05% clobetasol ointment for psoriatic nails. MATERIALS AND METHODS: Psoriasis patients, each with three fingernails with similar degrees of severity, were randomly recruited for intralesional triamcinolone injection group, 0...
May 21, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29780829/the-effect-of-c-arm-mobility-and-field-of-vision-on-radiation-exposure-in-the-treatment-of-proximal-femoral-fractures-a-randomized-clinical-trial
#4
Mahmut Kalem, Kerem Başarır, Hakan Kocaoğlu, Ercan Şahin, Hakan Kınık
Objectives: To examine the effect of fluoroscopy devices with different sizes of image intensifier and C-arm maneuverability on operating time, fluoroscopy time, radiation dose and reduction, and fixation quality at intertrochanteric femoral fractures. Design: Single-center, randomized, prospective study. Setting: Academic Level I trauma hospital. Patients and Intervention: 34 patients treated with cephalomedullary nailing for a stable, intertrochanteric proximal femur fracture (OTA A1)...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29780134/plummer-s-nails-onycholysis-in-a-thyroid-stimulation-blocking-antibody-tsbab-positive-patient-with-hypothyroidism
#5
Nobuyuki Takasu, Hiromichi Seki
No abstract text is available yet for this article.
May 18, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29778751/cortical-erosion-after-elastic-stable-intramedullary-nail-fixation-for-pediatric-long-bone-fractures-case-series-according-to-the-site
#6
Kun-Bo Park, Je-Hyun Yoo, Seok-Woo Kim, Yoon Hae Kwak
BACKGROUND: Elastic stable intramedullary nail (ESIN) is widely used for treatment of long bone fractures in children. However, migration of the nail or cortical bone erosion in children has been reported. This study was conducted to investigate the incidence of cortical erosion according to the site and cortical erosion type. MATERIALS AND METHODS: A total of 221 normally developing children (223 fractures) who were treated with ESIN for fractures of the long bones without cortical breakage at immediate postoperative radiography and with the ESIN in position for more than 6 months were included...
May 17, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29778152/occurrence-of-perfluoroalkyl-substances-in-matched-human-serum-urine-hair-and-nail
#7
Yuxin Wang, Yuxin Zhong, Jingguang Li, Jianqing Zhang, Bing Lyu, Yunfeng Zhao, Yongning Wu
The purpose of this study was to determine perfluoroalkyl substances (PFASs) in human serum, urine, hair and nail from general populations, and to investigate the possibility for human urine, hair and nail used as the biomonitoring sample for PFASs exposure. We detected the concentrations of PFHxA, PFOA, PFNA, PFDA, PFUnDA, PFDoA, PFHxS and PFOS in 39 matched human serum, urine, hair and nail samples from Shenzhen in China. The detection frequency and the median level of PFOS were all higher than that of the other PFASs in four matrices...
May 2018: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/29774605/mixed-infections-are-a-critical-factor-in-the-treatment-of-superficial-mycoses
#8
A Gawaz, G Weisel
BACKGROUND: Superficial fungal infections of the skin, nails and hair are common with Trichophyton rubrum and Candida albicans being the main pathogens. Yet, in some patients, mycological cultures show growth of more than one fungal agent in the same anatomical region. OBJECTIVE: This study analyses prevalence, frequency and fungal agents found in superficial fungal mixed infections and discusses consequences for diagnostics and treatment. METHODS: Mycological data obtained between January 2006 to December 2015 from clinical specimens from a total cohort of 7733 patients with suspected fungal infections were retrospectively analysed...
May 17, 2018: Mycoses
https://www.readbyqxmd.com/read/29772988/combined-labeled-leukocyte-and-technicium-99-sulfur-colloid-bone-marrow-imaging-differentiating-primary-pyomyositis-pseudotumor-from-osteomyelitis-and-multiple-bone-infarcts
#9
Paul W Perdue, Allison B Spitzer, Dipal Chatterjee, Srinivas Kolla, Aditya V Maheshwari
A 53 year old-female patient with lupus had undergone a cephalo-medullary nailing for a femur shaft fracture 30 years ago. This was complicated by osteomyelitis, requiring multiple debridement procedures and hardware removal. Recently, she developed a painful soft tissue mass in the same region, which was ultimately diagnosed as pyomyositis. Because of chronic bone changes due to her past history, traditional imaging could not differentiate between osteomyelitis infarction and pseudotumor. A combined indium-labeled leukocyte scan with a technetium-99 sulfur colloid marrow scan ruled out osteomyelitis and guided proper treatment without osseous debridement and thus prevented unnecessary cross-contamination of the bone...
2018: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/29771856/vitamin-e-phosphate-coating-stimulates-bone-deposition-in-implant-related-infections-in-a-rat-model
#10
Arianna B Lovati, Marta Bottagisio, Susanna Maraldi, Martina B Violatto, Monica Bortolin, Elena De Vecchi, Paolo Bigini, Lorenzo Drago, Carlo L Romanò
BACKGROUND: Implant-related infections are associated with impaired bone healing and osseointegration. In vitro antiadhesive and antibacterial properties and in vivo antiinflammatory effects protecting against bone loss of various formulations of vitamin E have been demonstrated in animal models. However, to the best of our knowledge, no in vivo studies have demonstrated the synergistic activity of vitamin E in preventing bacterial adhesion to orthopaedic implants, thus supporting the bone-implant integration...
June 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29771287/term-or-preterm-cesarean-section-delivery-does-not-lead-to-long-term-detrimental-consequences-in-mice
#11
Morgane Chiesa, Damien Guimond, Roman Tyzio, Alexandre Pons-Bennaceur, Natalia Lozovaya, Nail Burnashev, Diana C Ferrari, Yehezkel Ben-Ari
Epidemiological studies have provided contradictory data on the deleterious sequels of cesarean section (C-section) delivery and their links with developmental brain disorders such as Autism Spectrum Disorders. To gain better insight on these issues, we have now compared physiological, morphological, and behavioral parameters in vaginal, term, and preterm C-section delivered mice. We report that C-section delivery does not lead to long-term behavioral alterations though preterm C-section delivery modifies communicative behaviors in pups...
May 16, 2018: Cerebral Cortex
https://www.readbyqxmd.com/read/29770837/systematic-investigations-of-endogenous-cortisol-and-cortisone-in-nails-by-lc-ms-ms-and-correlation-to-hair
#12
Tina M Binz, Franziska Gaehler, Clarissa D Voegel, Mathias Hofmann, Markus R Baumgartner, Thomas Kraemer
Hair samples are increasingly used for measuring the long-term stress mediator cortisol. However, hair is not always available and nails (finger or toe), as a keratinized matrix, may be an alternative to hair. In order to measure cortisol and cortisone in the nail matrix, an LC-MS/MS method has been developed and validated using 13 C3 -labeled surrogate analytes. Both analytes were measured in ESI negative mode as formic acid adducts. Different sample preparation techniques were assessed, and single-step extraction in methanol was established for determination of cortisone and cortisol in the nail matrix...
May 17, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29770583/angle-stable-interlocking-intramedullary-nails-for-tibial-plateau-fractures
#13
Peng Jia, Feng-Cheng Lu, Kifayat Ullah, Man Zhang, Yan-Sheng Dong, Chao Xiong, Zhi-Hui Zhao, Jin-Feng Wang, Ju-Wen Chen, Yong-Qing Wang
OBJECTIVE: Angle stable interlocking intramedullary nail (ASIN), a novel technique, has rarely been used for treatment of tibial plateau fractures (TPF). This retrospective study was designed to introduce this novel technique, ASIN, as well as to describe the initial experience and verify the effectiveness when ASIN was used for the management for TPF. METHODS: A cohort of 19 cases with closed TPF aged from 18-70 years with at least 23 months follow-up from November 2008 to September 2013 was analyzed retrospectively...
May 16, 2018: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29770234/a-case-of-congenital-syphilis-presenting-with-unusual-skin-eruptions
#14
Alexander K C Leung, Kin Fon Leong, Joseph M Lam
Once believed to be a rare disease in developed countries, recent data suggest that there is a surge in incidence of congenital syphilis in many developed countries. Diagnosis of congenital syphilis can be difficult because more than two-thirds of affected infants are asymptomatic at birth, and signs of symptomatic infants may be nonspecific or subtle. On top of this, some affected infants may have atypical presentations. Familiarity with the diverse presentations is essential to diagnosis. We report a 2-week-old male infant with congenital syphilis whose cutaneous manifestations included diffuse, erythematous keratoderma with desquamation and fissures on his hands and feet, multiple linear scaly fissures at the angles of his mouth, and onychauxis of the fingernails and toenails To our knowledge, diffuse, erythematous keratoderma of the hands and feet and thick nails have not been reported previously in congenital syphilis...
2018: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29770205/beginning-at-the-ends-telomeres-and-human-disease
#15
REVIEW
Sharon A Savage
Studies of rare and common illnesses have led to remarkable progress in the understanding of the role of telomeres (nucleoprotein complexes at chromosome ends essential for chromosomal integrity) in human disease. Telomere biology disorders encompass a growing spectrum of conditions caused by rare pathogenic germline variants in genes encoding essential aspects of telomere function. Dyskeratosis congenita, a disorder at the severe end of this spectrum, typically presents in childhood with the classic triad of abnormal skin pigmentation, nail dystrophy, and oral leukoplakia, accompanied by a very high risk of bone marrow failure, cancer, pulmonary fibrosis, and other medical problems...
2018: F1000Research
https://www.readbyqxmd.com/read/29766741/simultaneous-intraoperative-measurement-of-cadaver-ankle-and-subtalar-joint-compression-during-arthrodesis-with-intramedullary-nail-screws-and-tibiotalocalcaneal-plate
#16
Kamran S Hamid, Richard R Glisson, Joel G Morash, Andrew P Matson, James K DeOrio
BACKGROUND: Suboptimal tibiotalocalcaneal arthrodesis (TTCA) fusion rates may result from inadequate compression that increases motion and interferes with bony bridging. The aim of this study was to evaluate compressive forces at the ankle and subtalar joints with 3 contemporary TTCA constructs. METHODS: Thirty fresh-frozen cadaveric lower extremity specimens were divided into 3 groups of 10 each: 3 partially threaded cannulated screws, hindfoot nail, and lateral plate...
May 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29765974/diving-under-nail-plate
#17
Carlota Gutiérrez García-Rodrigo, Virginia Velasco Tamaríz, Marta Prieto Barrios, José Luis Rodríguez-Peralto, Beatriz García Bracamonte
No abstract text is available yet for this article.
April 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29765967/nail-pyogenic-granuloma-following-treatment-with-blinatumomab
#18
Dilshad Paurobally, Josette Andre, Bertrand Richert
No abstract text is available yet for this article.
April 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29765964/a-rare-syndrome-resembling-scleroderma-huriez-syndrome
#19
Nil Su Çelik, Şirin Yaşar, Sema Aytekin, Pembegül Güneş
Huriez syndrome, also referred to as "sclerotylosis," is a rare autosomal dominant genodermatosis characterized by the triad of congenital scleroatrophy of the distal extremities, palmoplantar keratoderma, and hypoplastic nails. The development of aggressive squamous cell carcinoma (SCC) arising in the scleroatrophic area is also a distinctive feature of the syndrome. Early diagnosis is important due to the early onset, mostly in the third to fourth decades of life, and aggressive progress of SCC, which occurs in around 15% of affected individuals...
April 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29765961/efinaconazole-10-topical-solution-case-review-of-onychomycosis-patients-who-were-completely-cured-at-week-24
#20
Boni E Elewski, Antonella Tosti, Tina Lin
Background: Clinical studies with topical onychomycosis agents typically involve daily application over 48 weeks. Some patients are cured earlier; however, individual data are limited. Objective: The aim of this study was to assess baseline demographics/disposition of onychomycosis patients completely cured at week 24 following daily efinaconazole treatment. Methods: We conducted a week-24 case review of 2 identical, multicenter, randomized, double-blind, vehicle-controlled studies on 1,655 patients with mild-to-moderate onychomycosis...
April 2018: Skin Appendage Disorders
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