Eirini Kostopoulou, Dimitra Kalavrizioti, Panagiota Davoulou, Evangelos Papachristou, Xenophon Sinopidis, Sotirios Fouzas, Theodore Dassios, Despoina Gkentzi, Stavroula Ioanna Kyriakou, Ageliki Karatza, Gabriel Dimitriou, Dimitrios Goumenos, Bessie E Spiliotis, Panagiotis Plotas, Marios Papasotiriou
UNLABELLED: Inflammation plays a crucial role in diabetes and obesity through macrophage activation. Macrophage chemoattractant protein-1 (MCP-1), activin-A, and clusterin are chemokines with known roles in diabetes and obesity. The aim of this study is to investigate their possible diagnostic and/or early prognostic values in children and adolescents with obesity and type-1 diabetes mellitus (T1DM). METHODS: We obtained serum samples from children and adolescents with a history of T1DM or obesity, in order to measure and compare MCP-1, activin-A, and clusterin concentrations...
February 19, 2024: Diagnostics