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https://www.readbyqxmd.com/read/28944575/seven-tesla-magnetization-transfer-imaging-to-detect-multiple-sclerosis-white-matter-lesions
#1
I-Jun Chou, Su-Yin Lim, Radu Tanasescu, Ali Al-Radaideh, Olivier E Mougin, Christopher R Tench, William P Whitehouse, Penny A Gowland, Cris S Constantinescu
BACKGROUND AND PURPOSE: Fluid-attenuated inversion recovery (FLAIR) imaging at 3 Tesla (T) field strength is the most sensitive modality for detecting white matter lesions in multiple sclerosis. While 7T FLAIR is effective in detecting cortical lesions, it has not been fully optimized for visualization of white matter lesions and thus has not been used for delineating lesions in quantitative magnetic resonance imaging (MRI) studies of the normal appearing white matter in multiple sclerosis...
September 25, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/28943706/theoretical-predictions-for-spatially-focused-heating-of-magnetic-nanoparticles-guided-by-magnetic-particle-imaging-field-gradients
#2
Rohan Dhavalikar, Carlos Rinaldi
Magnetic nanoparticles in alternating magnetic fields (AMFs) transfer some of the field's energy to their surroundings in the form of heat, a property that has attracted significant attention for use in cancer treatment through hyperthermia and in developing magnetic drug carriers that can be actuated to release their cargo externally using magnetic fields. To date, most work in this field has focused on the use of AMFs that actuate heat release by nanoparticles over large regions, without the ability to select specific nanoparticle-loaded regions for heating while leaving other nanoparticle-loaded regions unaffected...
December 1, 2016: Journal of Magnetism and Magnetic Materials
https://www.readbyqxmd.com/read/28943537/transient-prosopometamorphopsia-restricted-to-the-left-eye-caused-by-ischemia-at-the-right-splenium-of-the-corpus-callosum
#3
Naoko Funatsu, Mikito Hayakawa, Naoki Tokuda, Kazunori Toyoda
We herein report a patient who developed transient prosopometamorphopsia restricted to the left eye caused by ischemia of the right splenium of the corpus callosum. A 66-year-old right-handed woman suddenly noticed that the left eyes of people she encountered appeared markedly adducted to their noses. On emergent admission, neurological and ophthalmological examinations revealed no abnormalities. Diffusion-weighted magnetic resonance imaging showed a small, hyperintense lesion at the right splenium of the corpus callosum...
September 25, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28942735/representation-of-cardiovascular-magnetic-resonance-in-the-aha-acc-guidelines
#4
Florian von Knobelsdorff-Brenkenhoff, Guenter Pilz, Jeanette Schulz-Menger
BACKGROUND: Whereas evidence supporting the diagnostic value of cardiovascular magnetic resonance (CMR) has increased, there exists significant worldwide variability in the clinical utilization of CMR. A recent study demonstrated that CMR is represented in the majority of European Society for Cardiology (ESC) guidelines, with a large number of specific recommendations in particular regarding coronary artery disease. To further investigate the gap between the evidence and clinical use of CMR, this study analyzed the role of CMR in the guidelines of the American College of Cardiology (ACC) and American Heart Association (AHA)...
September 25, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28942167/cracks-in-dried-deposits-of-hematite-ellipsoids-interplay-between-magnetic-and-hydrodynamic-torques
#5
Hisay Lama, Ranajit Mondal, Madivala G Basavaraj, Dillip K Satapathy
The orientation and morphology of cracks in coffee-ring like particulate deposit obtained by drying sessile drops containing anisotropic magnetic particles strongly depends on the magnitude of the applied magnetic field and its direction. This opens up the possibility of tuning the micro-structure of cracks via suitable manipulation of magnetic and hydrodynamic torques on the particles which has potential applications in nano-fabrication and field driven self-assembly. We report a systematic study of magnetic field driven self-assembly of hematite ellipsoids in sessile drops dried on solid substrates and resulting crack patterns...
September 12, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28941937/exploiting-homing-abilities-of-cell-carriers-targeted-delivery-of-nanoparticles-for-cancer-therapy
#6
REVIEW
Pamela Tiet, Jacob Berlin
Off target toxicities is one of the hallmarks of conventional chemotherapy as only a tiny percentage of the injected dose actually reaches the tumor(s). Numerous strategies have been employed in attempts to achieve targeted therapeutic delivery to tumors. One strategy that has received immense attention has been the packaging of these chemotherapeutics into nanoparticles and relying on the enhanced permeation and retention (EPR) effect for targeting. However, few, if any, nanoformulations have been used clinically that actually show enhanced drug delivery to tumors...
September 20, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28941258/magnetic-quantum-dots-steer-and-detach-microtubules-from-kinesin-coated-surfaces
#7
Kalpesh D Mahajan, Yixiao Cui, C Jenny Dorcéna, Nathan F Bouxsien, George D Bachand, Jeffrey J Chalmers, Jessica O Winter
BACKGROUND: The microtubule (MT)-kinesin system has been extensively studied because of its role in cellular processes, as well as its potential use for controllably transporting objects at the nanoscale. Thus, there is substantial interest in methods to evaluate MT properties, including bending radius and the binding energy of kinesin motor proteins to MT tracks. Current methods to identify these properties include optical tweezers, microfluidic devices, and magnetic fields. METHODS: Here, the use of magnetic quantum dots (i...
September 23, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28940601/suppression-of-arabidopsis-flowering-by-near-null-magnetic-field-is-mediated-by-auxin
#8
Chunxiao Xu, Yuxia Zhang, Yang Yu, Yue Li, Shufeng Wei
We previously found that flowering of Arabidopsis was suppressed by near-null magnetic field, which was related to cryptochrome. Auxin plays an important role in Arabidopsis flowering. To test whether auxin is involved in the suppression of Arabidopsis flowering by near-null magnetic field, we detected auxin level and expressions of auxin transport and signaling genes in wild-type Arabidopsis plants and cryptochrome double mutant, cry1/cry2, grown in near-null magnetic field. We found that indole-3-acetic acid (IAA) level in roots of wild-type plants in near-null magnetic field was significantly increased compared with the local geomagnetic field control, while IAA level in rosettes of 33-day-old wild-type plants in near-null magnetic field was significantly lower than the control...
September 20, 2017: Bioelectromagnetics
https://www.readbyqxmd.com/read/28940581/a-novel-approach-to-probing-in-vivo-metabolite-relaxation-linear-quantification-of-spatially-modulated-magnetization
#9
Linqing Li, Ningzhi Li, Li An, Jun Shen
PURPOSE: Conventional sequences for metabolite transverse relaxation quantification all generally measure signal changes at different echo times (TEs). However, quantification results obtained via these conventional methods can be very different and are highly dependent on the type of sequence being applied. TE-dependent effects such as diffusion, macromolecule baseline, and J-coupling modulation contribute significantly to these differences. Here, we propose a novel technique-multiple flip angle pulse-driven ratio of longitudinal steady states (MARzss)-for preparing magnetization with T2 /T1 weighting...
September 23, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28940000/fabrication-of-novel-surface-imprinted-magnetic-graphene-oxide-grafted-cellulose-nanocrystals-for-selective-extraction-and-fast-adsorption-of-fluoroquinolones-from-water
#10
Nan Wang, Yan-Fei Wang, Ahmed M Omer, Xiao-Kun Ouyang
A novel adsorbent based on the surface of magnetic graphene oxide-grafted cellulose nanocrystal molecularly imprinted polymers (Mag@GO-g-CNCs@MIPs) was developed for the selective extraction and fast adsorption of fluoroquinolones (FQs) from river water samples. Cellulose nanocrystals (CNCs) were grafted onto activated graphene oxide (GO), and the surfaces of the obtained magnetic GO-g-CNC particles were molecularly imprinted with polymers using ofloxacin (OFX) as a template molecule and methacrylic acid (MAA) as a functional monomer...
September 22, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28939909/exchange-driven-magnetic-logic
#11
Odysseas Zografos, Mauricio Manfrini, Adrien Vaysset, Bart Sorée, Florin Ciubotaru, Christoph Adelmann, Rudy Lauwereins, Praveen Raghavan, Iuliana P Radu
Direct exchange interaction allows spins to be magnetically ordered. Additionally, it can be an efficient manipulation pathway for low-powered spintronic logic devices. We present a novel logic scheme driven by exchange between two distinct regions in a composite magnetic layer containing a bistable canted magnetization configuration. By applying a magnetic field pulse to the input region, the magnetization state is propagated to the output via spin-to-spin interaction in which the output state is given by the magnetization orientation of the output region...
September 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28939890/an-open-label-one-arm-dose-escalation-study-to-evaluate-safety-and-tolerability-of-extremely-low-frequency-magnetic-fields-in-acute-ischemic-stroke
#12
Fioravante Capone, Micaela Liberti, Francesca Apollonio, Francesca Camera, Stefania Setti, Ruggero Cadossi, Carlo Cosimo Quattrocchi, Vincenzo Di Lazzaro
Extremely low frequency magnetic fields (ELF-MF) could be an alternative neuroprotective approach for ischemic stroke because preclinical studies have demonstrated their effects on the mechanisms underlying ischemic damage. The purpose of this open-label, one arm, dose-escalation, exploratory study is to evaluate the safety and tolerability of ELF-MF in patients with acute ischemic stroke. Within 48 hours from the stroke onset, patients started ELF-MF treatment, daily for 5 consecutive days. Clinical follow-up lasted 12 months...
September 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28939885/tuning-magnetoresistance-in-molybdenum-disulphide-and-graphene-using-a-molecular-spin-transition
#13
Subhadeep Datta, Yongqing Cai, Indra Yudhistira, Zebing Zeng, Yong-Wei Zhang, Han Zhang, Shaffique Adam, Jishan Wu, Kian Ping Loh
Coupling spins of molecular magnets to two-dimensional (2D) materials provides a framework to manipulate the magneto-conductance of 2D materials. However, with most molecules, the spin coupling is usually weak and devices fabricated from these require operation at low temperatures, which prevents practical applications. Here, we demonstrate field-effect transistors based on the coupling of a magnetic molecule quinoidal dithienyl perylenequinodimethane (QDTP) to 2D materials. Uniquely, QDTP switches from a spin-singlet state at low temperature to a spin-triplet state above 370 K, and the spin transition can be electrically transduced by both graphene and molybdenum disulphide...
September 22, 2017: Nature Communications
https://www.readbyqxmd.com/read/28939841/large-room-temperature-spin-to-charge-conversion-signals-in-a-few-layer-graphene-pt-lateral-heterostructure
#14
Wenjing Yan, Edurne Sagasta, Mário Ribeiro, Yasuhiro Niimi, Luis E Hueso, Fèlix Casanova
Electrical generation and detection of pure spin currents without the need of magnetic materials are key elements for the realization of full electrically controlled spintronic devices. In this framework, achieving a large spin-to-charge conversion signal is crucial, as considerable outputs are needed for plausible applications. Unfortunately, the values obtained so far have been rather low. Here we exploit the spin Hall effect by using Pt, a non-magnetic metal with strong spin-orbit coupling, to generate and detect pure spin currents in a few-layer graphene channel...
September 22, 2017: Nature Communications
https://www.readbyqxmd.com/read/28939516/highly-selective-adsorption-of-hydroquinone-by-hydroxyethyl-cellulose-functionalized-with-magnetic-ionic-liquid
#15
Chaofan Ding, Yue Li, Yanhui Wang, Jianbo Li, Yuanling Sun, Yanna Lin, Weiyan Sun, Chuannan Luo
Magnetic hydroxyethyl cellulose/ionic liquid (MHEC/IL) materials were fabricated through a facile and fast process and their application as excellent adsorbents for hydroquinone was also demonstrated. The thermal stability, chemical structure and magnetic property of the MHEC/IL were characterized by the Scanning electron microscope (SEM), Transmission Electron Microscope (TEM), Fourier transform infrared spectrometer (FT-IR) and X-ray diffraction (XRD), respectively. The adsorbents were used for the removal of hydroquinone from simulated wastewater with a fast solid-liquid separation in the presence of external magnetic field...
September 19, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28939433/robust-inter-subject-audiovisual-decoding-in-functional-magnetic-resonance-imaging-using-high-dimensional-regression
#16
Gal Raz, Michele Svanera, Neomi Singer, Gadi Gilam, Maya Bleich Cohen, Tamar Lin, Roee Admon, Tal Gonen, Avner Thaler, Roni Y Granot, Rainer Goebel, Sergio Benini, Giancarlo Valente
Major methodological advancements have been recently made in the field of neural decoding, which is concerned with the reconstruction of mental content from neuroimaging measures. However, in the absence of a large-scale examination of the validity of the decoding models across subjects and content, the extent to which these models can be generalized is not clear. This study addresses the challenge of producing generalizable decoding models, which allow the reconstruction of perceived audiovisual features from human magnetic resonance imaging (fMRI) data without prior training of the algorithm on the decoded content...
September 19, 2017: NeuroImage
https://www.readbyqxmd.com/read/28938963/study-design-and-rationale-for-elpis-a-phase-i-iib-randomized-pilot-study-of-allogeneic-human-mesenchymal-stem-cell-injection-in-patients-with-hypoplastic-left-heart-syndrome
#17
Sunjay Kaushal, Brody Wehman, Nicholas Pietris, Casey Naughton, Soren M Bentzen, Grace Bigham, Rachana Mishra, Sudhish Sharma, Luca Vricella, Allen D Everett, Kristopher B Deatrick, Sihong Huang, Helina Mehta, William A Ravekes, Naru Hibino, Darcy L Difede, Aisha Khan, Joshua M Hare
Despite advances in surgical technique and postoperative care, long-term survival of children born with hypoplastic left heart syndrome (HLHS) remains limited, with cardiac transplantation as the only alternative for patients with failing single ventricle circulations. Maintenance of systemic right ventricular function is crucial for long-term survival, and interventions that improve ventricular function and avoid or defer transplantation in patients with HLHS are urgently needed. We hypothesize that the young myocardium of the HLHS patient is responsive to the biological cues delivered by bone marrow-derived mesenchymal stem cells (MSCs) to improve and preserve right ventricle function...
October 2017: American Heart Journal
https://www.readbyqxmd.com/read/28938836/spin-polarization-and-magnetic-characteristics-at-c6h6-co2mnsi-001-spinterface
#18
Meifang Sun, Xiaocha Wang, Wenbo Mi
Organic materials with mechanical flexibility, low cost, chemical engineering, and long spin lifetime attract considerable attention for building spintronic devices. Here, a C6H6/Co2MnSi(001) spinterface is investigated by first-principles calculations and spin-polarized scanning tunneling microscopy simulations. Several high symmetry adsorption sites are discussed, together with two possible surface terminations of Co2MnSi(001). An inversion of the spin polarization is induced near EF even in the case of an external electric field, indicating that C6H6 can act as a spin filter to exploit the spin injection efficiency in organic spintronic devices...
September 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28938274/pain-free-3-t-mri-scans-in-cochlear-implantees
#19
Ingo Todt, Anja Tittel, Arne Ernst, Philipp Mittmann, Sven Mutze
OBJECTIVE: For cochlear implant recipients, undergoing magnetic resonance imaging (MRI) scans is associated with safety risks and potential side effects. Even following safety guidelines, potential complications (e.g., pain, magnet dislocation, image artifacts) are possible during 1.5 Tesla (T) MRI scans. The stronger static magnetic field of a 3.0 T scanner is associated with further risks of complication, including implant demagnetization. These complications led to the recent development of rotatable internal receiver magnets with a diametrical magnetization...
September 21, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28938157/adsorption-combined-with-superconducting-high-gradient-magnetic-separation-technique-used-for-removal-of-arsenic-and-antimony
#20
Zenglu Qi, Tista Prasai Joshi, Ruiping Liu, Yiran Li, Huijuan Liu, Jiuhui Qu
Manganese iron oxide (MnFe2O4), an excellent arsenic(As)/antimony(Sb) removal adsorbent, is greatly restricted for the solid-liquid separation. Through the application of superconducting high gradient magnetic separation (HGMS) technique, we herein constructed a facility for the in situ solid-liquid separation of micro-sized MnFe2O4 adsorbent in As/Sb removal process. To the relative low initial concentration 50.0μgL(-1), MnFe2O4 material sorbent can still decrease As or Sb below US EPA's drinking water standard limit...
September 7, 2017: Journal of Hazardous Materials
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