Poly l lactic acid thread

BACKGROUND: Fractionated carbon dioxide (CO2) lasers are a new treatment modality for skin resurfacing. The cosmetic rejuvenation market abounds with various injectable devices (poly-L-lactic acid, polymethyl-methacrylate, collagens, hyaluronic acids, silicone). The objective of this study is to examine the efficacy and safety of 10,600-nm CO2 fractional laser on facial skin with previous volume injections. MATERIALS AND METHODS: This is a retrospective study including 14 patients treated with fractional CO2 laser and who have had previous facial volume restoration...

BACKGROUND: Flatfoot deformities are common in children and are treated using many conservative and surgical approaches. Subtalar extra-articular arthroereisis, in particular, limits talar motion, spares the subtalar joint, and prevents excessive subtalar joint pronation. Addressing the underlying equinus deformity with gastrocnemius recession is an important factor in optimizing outcomes in patients with flatfoot deformity. METHODS: This study included 20 children, 4 to 17 years old...

PURPOSE: A biochemical approach to implant surface modification may offer an alternative to physicochemical and morphologic methods for obtaining desirable bone-implant interfaces. The objective of this study was to investigate the bone tissue response to anodized titanium implant surfaces coated with a poly(D,L-lactide-co-glycolide) (PLGA) solution mixed with 1α,25-diydroxyvitamin D3 (1α,25-(OH)2D3) via an electrospray technique. MATERIALS AND METHODS: Threaded implants were manufactured and anodized under 300 V at 660 Hz for 3 minutes (control group)...

INTRODUCTION: Bioabsorbable screws are, at the expense of metal screws, increasingly used as fixation device in ACL-reconstructions. The possible advantages with bioabsorbable screws are better postoperative MRI evaluations and easier revision surgery. PURPOSE: The aim of this study was to compare the clinical outcome after ACL-reconstructions with BPTB-grafts fixed with metal interference screws or bioabsorbable screws 7 years postoperatively. The resorption of the bioabsorbable screws was also analyzed...

Injectable poly-L-lactic acid is United States Food and Drug Administration-approved for the restoration and/or correction of the signs of lipoatrophy in people with human immunodeficiency virus and for use in immune-competent people for the correction of nasolabial fold contour deficiencies. Current prescribing information recommends using either a tunneling or threading technique in a grid or cross-hatched pattern or a depot technique (in thin skin areas) to administer multiple passes of injectable poly-L-lactic acid per treatment session via a 26-gauge needle...

This paper presents a model for the change in Young's modulus of biodegradable polymers due to hydrolysis cleavage of the polymer chains. The model is based on the entropy spring theory for amorphous polymers. It is assumed that isolated polymer chain cleavage and very short polymer chains do not affect the entropy change in a linear biodegradable polymer during its deformation. It is then possible to relate the Young's modulus to the average molecular weight in a computer simulated hydrolysis process of polymer chain sessions...

In this work, drug-loaded fibers and threads were successfully fabricated by combining electrospinning with aligned fibers collection. Two different electrospinning processes, that is, blend and coaxial electrospinning, to incorporate a model drug tetracycline hydrochloride (TCH) into poly(L-lactic acid) (PLLA) fibers have been used and compared with each other. The resulting composite ultrafine fibers and threads were characterized through scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, differential scanning calorimetry, and tensile testing...

The aim of the study was to assess the hard tissue response of a composite hydroxyapatite/poly L-lactic acid (HA/PLLA) interference screw for anterior cruciate ligament (ACL) reconstruction compared to a standard PLLA screw. Twelve skeletally mature rams underwent unilateral ACL reconstruction using an autologous bone-patellar tendon graft. Each animal received either two test HA/PLLA interference screws or two control PLLA interference screws. Animals were sacrificed at 6 and 12 months post-implantation and the operated knees excised...

The surgical correction of hammer toe deformity of the lesser toes is one of the most commonly performed forefoot procedures. In general, percutaneous Kirschner wires are used to provide fixation to the resected proximal interphalangeal joint. Although these wires are effective, issues such as pin tract infections as well as difficult postoperative management by patients make alternative fixation methods desirable. This study biomechanically compared a threaded/barbed bioabsorbable fixation implant made of a copolymer of 82% poly-L-lactic acid and 18% polyglycolic acid with a 1...

PURPOSE: To evaluate the long term in vivo degradation of poly-L-lactic acid (PLLA) interference screws with computed tomography (CT) and radiography as used in patellar tendon autograft anterior cruciate ligament (ACL) reconstruction. METHODS: A total of 20 patients who had undergone patellar tendon autograft ACL reconstruction fixed with PLLA screws at least 7 years earlier were evaluated by physical examination, radiography, and CT to determine whether PLLA screw reabsorption and bone ingrowth had occurred...

OBJECTIVE: To assess the treatment effect of intra-articular fracture with absorbable screws and rods. METHODS: From June 1998 to August 2004, 35 patients with intra-articular fracture were treated by absorbable screws and rods made of self-reinforced polyglycolic acid (SR-PGA) and self-reinforced poly-L-Lactic acid (SR-PLLA). Of 35 patients, 30 were males and 5 were females (aged from 4 to 62 years). All cases had intra-articular or periarticular fracture. The interval between injury and operation was 3 hours to 29 days...

The need to provide rigid bony fixation in the surgical treatment of craniofacial deformities has inspired an on-going evolution of surgical innovations and implants. Because of the young age of many treated craniosynostosis patients and the unique pattern of cranial vault growth, the extensive implantation of metal devices is potentially problematic. The use of resorbable plate and screw devices offers all of the benefits of rigid fixation without many of their potential risks. Since the introduction of resorbable plate and screw devices in 1996, tens of thousands of craniofacial patients have received implants, but long-term results from a large series have yet to be reported...

BACKGROUND: Bioabsorbable thread pin has been used for internal fixation of bone. The results of resection arthroplasty of the lesser metatarsophalangeal (MTP) joints using internal intramedullary fixation with bioabsorbable pins have not been reported. METHODS: Resection arthroplasty of the MTP joints of the lesser toes with poly-L-lactic acid (PLLA) thread pins or Kirschner wires was performed at random in reconstruction of the 87 rheumatoid forefeet (62 patients) with a grommet-protected silicone-rubber implant insertion of the first MTP joint...

Several bioabsorbable internal fixation systems are currently in use in the field of bone surgery. To test the mechanical properties of recently developed amorphous self-reinforced poly-L/DL-lactide [SR-P(L/DL)LA] 70/30 tacks in comparison with commercially available SR-P(L/DL)LA 70/30 (BioSorbFX; Bionx Implants Ltd) miniscrews, SR-P(L/DL)LA miniscrews (length = 6.0 mm, core diameter = 1.5 mm, thread diameter = 2.0 mm) and tacks (length = 5.4 mm, core diameter = 1.5 mm, thread diameter = 2.0 mm) were applied to human cadaveric metatarsal (MT) bones (6 pairs of fourth MT bones and 6 pairs of fifth MT bones from donors who were from 29 to 56 years of age at the time of death)...

The purpose of this research was to develop a bioabsorbable thread for tight fixation of fractured bones and to examine its mechanical performance in an in-vitro simulation study. The thread is a blend of bioabsorbable poly(L-lactic acid); (PLLA) and poly(epsilon-caprolactone); (PCL) fibers and can be tightly connected by fusion welding of the PCL fibers. The tying strength of the PLLA-PCL blend thread was 39.7 N, which was comparable to that of stainless steel wire. A testing machine was fabricated to measure the fatigue strength of the tying by simulating bone fixation...

A new poly(L-)lactic acid (PLLA) thread was tested by applying it in fascial closures of male Wistar rats. The tissue reactions around the thread and in the fascial union, and the changes on the surface and the mechanical properties of the thread were evaluated at 1, 3, 6, 12, 28, and 52 weeks following surgery. Histologically, the extension of the general inflammatory reaction and the number of the different cell types did not markedly change during the 52-week follow-up period. The surface of the thread was intact up to 28 weeks when examined with the scanning electron microscope...

Suture anchors are playing an increasingly important role in attaching tendons or ligaments to bone. Anchors are usually made of metallic or other nonbioabsorbable materials. The development of an absorbable suture anchor would provide a valuable tool for the surgeon; this characteristic would minimize the problems of anchor loosening, migration, interference with imaging studies, and the potential requirement for later implant removal. This study evaluated the in vivo histological response over time of the first generation Arthrex Expanding Suture Plug (ESP) (Arthrex Inc, Naples, FL)...

Erodible polymers are an alternative to metals for fracture fixation (for example, in the malleolus) and for maxillofacial reconstruction. In this study, the vascular response to eroding polylactide-polyglycolide copolymer threads was observed chronically in a bone chamber implant, with use of intravital microscopy. A bone chamber implant loaded with 100 microns thick polylactide-polyglycolide threads was implanted into the right tibia in 15 mature female New Zealand White rabbits. Periodic intravital microscopic observations were performed from the third to the tenth or twelfth week after implantation...