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https://www.readbyqxmd.com/read/28651207/metacognitive-therapy-versus-disorder-specific-cbt-for-comorbid-anxiety-disorders-a-randomized-controlled-trial
#1
Sverre Urnes Johnson, Asle Hoffart, Hans M Nordahl, Bruce E Wampold
Few studies have compared the effects of Metacognitive therapy (MCT) and Cognitive behavioral therapy (CBT) for comorbid anxiety disorders. In the current study we compared CBT and MCT for heterogeneous anxiety disorders in a residential setting. Ninety patients with a primary diagnosis of Post Traumatic Stress Disorder, Social Phobia or Panic disorder, with and without Agoraphobia, were randomized to either CBT or MCT. Patients were assessed at pre-treatment, post-treatment and one-year follow-up. Primary outcome measures were Beck Anxiety Inventory and ADIS IV and secondary outcome measures were SCID II, Beck Depression Inventory, Penn State Worry Questionnaire, The Symptom Checklist-90 and the Inventory of Interpersonal Problems-64...
June 15, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28651185/treatment-of-neurocognitive-symptoms-in-unipolar-depression-a-systematic-review-and-future-perspectives
#2
REVIEW
E Salagre, B Solé, Y Tomioka, B S Fernandes, D Hidalgo-Mazzei, M Garriga, E Jimenez, J Sanchez-Moreno, E Vieta, I Grande
BACKGROUND: Cognitive symptoms in Major Depressive Disorder (MDD) are persistent and commonly entail neurocognitive impairment and a decline in quality of life. This systematic review gathers the current scientific evidence on therapeutic strategies for neuropsychological impairment in MDD. METHOD: A systematic search on PubMed, PsycINFO and Clinicaltrials.gov was carried out on December 2016 according to PRISMA using Boolean terms to identify interventions for the treatment of cognitive dysfunction in MDD...
June 19, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28651103/does-cortisol-moderate-the-environmental-association-between-peer-victimization-and-depression-symptoms-a-genetically-informed-twin-study
#3
Mara Brendgen, Isabelle Ouellet-Morin, Sonia Lupien, Frank Vitaro, Ginette Dionne, Michel Boivin
Many youths who are victimized by peers suffer from depression symptoms. However, not all bullying victims show depression symptoms and individuals' biological sensitivity may play an important moderating role in this regard. In line with this notion, peer victimization has been associated with increased depressive symptoms in youth with higher basal cortisol secretion. It is unclear, however, whether this moderating effect of cortisol really concerns the environmental effect of peer victimization on depression...
June 19, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28651086/age-at-first-febrile-seizure-correlates-with-perinatal-maternal-emotional-symptoms
#4
Fanny Thébault-Dagher, Catherine M Herba, Jean R Séguin, Gina Muckle, Sonia J Lupien, Lionel Carmant, Marie-Noëlle Simard, Gabriel D Shapiro, William D Fraser, Sarah Lippé
OBJECTIVE: Prenatal exposure to stress and fever are factors lowering seizure threshold in animal models. The fever effect on seizure threshold is well documented in human infants, however the associations between maternal perinatal stress and infants' susceptibility to seizures is unknown. This is the first study in humans to investigate longitudinally, whether in humans, the effect of maternal perinatal emotional symptoms such as stress, anxiety and depression that may trigger a biological stress response on age at first seizure occurrence...
June 10, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28650957/determinants-of-generic-and-specific-health-related-quality-of-life-in-patients-with-parkinson-s-disease
#5
Xiao-Jing Tu, Wen-Juh Hwang, Hui-Ing Ma, Ling-Hui Chang, Shih-Pin Hsu
OBJECTIVES: Generic and disease-specific health-related quality of life (HRQoL) instruments may reflect different aspects of lives in patients with Parkinson's disease (PD) and thus be associated with different determinants. We used the same cluster of predictors for the generic and disease-specific HRQoL instruments to examine and compare the determinants of HRQoL. METHOD: HRQoL was measured in 92 patients with PD by the 36-item Short-Form Health Survey (SF-36) and the 39-item Parkinson's Disease Questionnaire (PDQ-39)...
2017: PloS One
https://www.readbyqxmd.com/read/28650923/the-effect-of-false-positive-mammograms-on-antidepressant-and-anxiolytic-initiation
#6
Joel E Segel, Rajesh Balkrishnan, Richard A Hirth
BACKGROUND: Despite reported increases in anxiety following a false-positive mammogram, there is little evidence the effect rises to the clinical level of initiating medication. OBJECTIVE: To analyze the effect of a false-positive mammogram on antidepressant or anxiolytic initiation and identify subpopulations most at risk. SUBJECTS: MarketScan commercial and Medicaid claims databases used to identify women ages 40-64 undergoing screening mammography with no prior antidepressant or anxiolytic claims...
June 23, 2017: Medical Care
https://www.readbyqxmd.com/read/28650777/a-transdiagnostic-examination-of-decreased-intolerance-of-uncertainty-and-treatment-outcome
#7
Kimberly Stevens, Travis Rogers, Moselle Campbell, Thröstur Björgvinsson, Sarah Kertz
Intolerance of uncertainty (IU) is characterized by negative beliefs and reactions to uncertainty. IU is present in emotional disorders and may be a mechanism of change in treatment . There are two components of IU, prospective and inhibitory IU, that may be differentially associated with outcome. The current study tested associations between pre- and post-treatment changes in the components of IU, symptoms of anxiety and depression, and treatment outcome in a large diagnostically heterogeneous partial hospital sample...
June 26, 2017: Cognitive Behaviour Therapy
https://www.readbyqxmd.com/read/28650335/development-of-ad-like-symptoms-following-co-administration-of-alcl3-and-d-gal-in-rats-a-neurochemical-biochemical-and-behavioural-study
#8
Laraib Liaquat, Saara Ahmad, Sadia Sadir, Zehra Batool, Saima Khaliq, Saiqa Tabassum, Shaista Emad, Syeda Madiha, Sidrah Shahzad, Saida Haider
Alzheimer's disease (AD) is an age-related neurodegenerative disorder associated with neurochemical and neurobehavioural alterations. Aluminium (Al) is considered as a contributing factor in the etiology of several neurodegenerative disorders like AD. D-galactose (D-gal) is a physiological nutrient but over supply induces some neurochemical and biochemical changes that exacerbate natural aging process. In this study, we aimed to develop AD animal model by co-administration of Al and D-gal in rats. Male albino Wistar rats were intraperitoneally injected with AlCl3 and D-gal at a dose of 150mg/kg and 300mg/kg respectively for one week...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28650200/the-cortisol-c-reactive-protein-ratio-and-negative-affect-reactivity-in-depressed-adults
#9
Edward C Suarez, John S Sundy
OBJECTIVE: We evaluated the effect of the cortisol (CORT) to high sensitivity C-reactive protein (hsCRP) ratio on stress-induced negative affect (NA) reactivity and whether the association was moderated by depressive symptom severity and gender. The CORT/CRP ratio was used to evaluate the integrity of the negative feedback loop between the hypothalamic-pituitary-adrenal axis and inflammatory response system. METHOD: Basal CORT and hsCRP levels were measured in fasting blood samples from 198 medication-free and nonsmoking healthy men and women...
June 26, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28650179/political-activism-and-mental-health-among-black-and-latinx-college-students
#10
Elan C Hope, Gabriel Velez, Carly Offidani-Bertrand, Micere Keels, Myles I Durkee
OBJECTIVES: The current study investigates the utility of political activism as a protective factor against experiences of racial/ethnic (R/E) discrimination that negatively affect stress, anxiety, and depressive symptoms among Black and Latinx college freshmen at predominately White institutions. METHOD: Data come from the Minority College Cohort Study, a longitudinal investigation of Black and Latinx college students (N = 504; 44% Black). We conducted multiple regression analyses for each mental health indicator and tested for interaction effects...
June 26, 2017: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/28649892/are-we-exaggerating-neuropsychological-impairment-in-depression-reopening-a-closed-chapter
#11
Steffen Moritz, Katrin Stöckert, Marit Hauschildt, Hannah Lill, Lena Jelinek, Thomas Beblo, Sabrina Diedrich, Sönke Arlt
BACKGROUND: Meta-analyses conclude that individuals with depression display neurocognitive deficits. However, the extent to which some of these impairments occur due to secondary influences, and thus in part represent epiphenomena, has rarely been tested. Therefore, the authors examined the impact of performance motivation, attitude towards cognitive assessment, and momentary symptoms during assessment on neuropsychological test results in depression. RESEARCH DESIGN AND METHODS: Forty-five patients with depression and 60 nonclinical individuals underwent a comprehensive neuropsychological test battery...
June 26, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28649855/quality-of-life-and-its-factors-in-korean-elderly-with-mild-cognitive-impairment
#12
Younhee Kang, Eliza Lee
Based on the secondary data analysis, this study aimed to identify quality of life and factors that affect quality of life among Korean elderly with mild cognitive impairment. Demographic characteristics, physical factors, and psychosocial factors as well as quality of life of the elderly with mild cognitive impairment were comprehensively measured. The research subjects consisted of 348 home-resident elderly and their quality of life scores were relatively high at 29.86. Their quality of life varied according to education and gender, and instrumental activities of daily living (actual, latent), somatic symptoms, sleep quality, depression, and social support affected their quality of life...
June 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/28649729/socializing-problems-and-low-self-esteem-enhance-interpersonal-models-of-eating-disorders-evidence-from-a-clinical-sample
#13
Bronwyn C Raykos, Peter M McEvoy, Anthea Fursland
OBJECTIVE: The present study evaluated the relative clinical validity of two interpersonal models of the maintenance of eating disorders, IPT-ED (Rieger et al., ) and the interpersonal model of binge eating (Wilfley, MacKenzie, Welch, Ayres, & Weissman, ; Wilfley, Pike, & Striegel-Moore, ). While both models propose an indirect relationship between interpersonal problems and eating disorder symptoms via negative affect, IPT-ED specifies negative social evaluation as the key interpersonal problem, and places greater emphasis on the role of low self-esteem as an intermediate variable between negative social evaluation and eating pathology...
June 26, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28649602/using-a-smartphone-based-self-management-platform-to-support-medication-adherence-and-clinical-consultation-in-parkinson-s-disease
#14
Rashmi Lakshminarayana, Duolao Wang, David Burn, K Ray Chaudhuri, Clare Galtrey, Natalie Valle Guzman, Bruce Hellman, Ben James, Suvankar Pal, Jon Stamford, Malcolm Steiger, R W Stott, James Teo, Roger A Barker, Emma Wang, Bastiaan R Bloem, Martijn van der Eijk, Lynn Rochester, Adrian Williams
The progressive nature of Parkinson's disease, its complex treatment regimens and the high rates of comorbid conditions make self-management and treatment adherence a challenge. Clinicians have limited face-to-face consultation time with Parkinson's disease patients, making it difficult to comprehensively address non-adherence. Here we share the results from a multi-centre (seven centres) randomised controlled trial conducted in England and Scotland to assess the impact of using a smartphone-based Parkinson's tracker app to promote patient self-management, enhance treatment adherence and quality of clinical consultation...
2017: NPJ Parkinson's Disease
https://www.readbyqxmd.com/read/28649389/cases-of-acute-mercury-poisoning-by-mercury-vapor-exposure-during-the-demolition-of-a-fluorescent-lamp-factory
#15
Sang Yoon Do, Chul Gab Lee, Jae Yoon Kim, Young Hoon Moon, Min Sung Kim, In Ho Bae, Han Soo Song
BACKGROUND: In 2015, workers dismantling a fluorescent lamp factory in Korea were affected by mercury poisoning from exposure to mercury vapor. CASE PRESENTATION: Eighteen out of the 21 workers who participated in the demolition project presented with symptoms of poisoning and, of these, 10 had persistent symptoms even at 18 months after the initial exposure to mercury vapor. Early symptoms of 18 workers included a general skin rash, pruritus, myalgia, sleep disturbance, and cough and sputum production...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28649311/screening-tools-for-evaluation-of-depression-in-chronic-obstructive-pulmonary-disease-copd-a-systematic-review
#16
K Bock, E Bendstrup, O Hilberg, A Løkke
Background: Anxiety and depression are common comorbid disorders in patients with chronic obstructive pulmonary disease (COPD), though estimates of their prevalence vary considerably. Depressive symptoms/depression are important comorbidities in COPD and an increasing interest is shown to these disorders. Depression may lead to reduced quality of life and increased morbidity and mortality. These statements underline the importance of implementing the use of screening instruments for depressive symptoms in a clinical setting...
2017: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28649302/differential-predictors-of-dsm-5-ptsd-and-icd-11-complex-ptsd-among-african-american-women
#17
Abigail Powers, Negar Fani, Sierra Carter, Dorthie Cross, Marylene Cloitre, Bekh Bradley
Background: Complex posttraumatic stress disorder (CPTSD) is proposed for inclusion in the ICD-11 as a diagnosis distinct from posttraumatic stress disorder (PTSD), reflecting deficits in affective, self-concept, and relational domains. There remains significant controversy over whether CPTSD provides useful diagnostic information beyond PTSD and other comorbid conditions, such as depression or substance use disorders. Objective: The present study examined differences in psychiatric presentation for three groups: traumatized controls, DSM-5 PTSD subjects, and ICD-11 CPTSD subjects...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/28649301/assessment-of-depression-in-veterans-across-missions-a-validity-study-using-rasch-measurement-models
#18
Karen-Inge Karstoft, Anni B S Nielsen, Tine Nielsen
Background: Depression is a common psychopathological outcome following military deployment. Previous studies have reported differing rates of post-deployment depression, indicating that the toll of war differs across missions. However, it is unclear to what degree the varying prevalence is due methodological differences. Studies comparing rates of depression across cohorts using the same methodology and ensuring measurement invariance are rare, leaving us with limited knowledge on the actual depression prevalence variance across missions...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/28649145/do-ssris-and-snris-reduce-the-frequency-and-or-severity-of-hot-flashes-in-menopausal-women
#19
Chris Stubbs, Lisa Mattingly, Steven A Crawford, Elizabeth A Wickersham, Jessica L Brockhaus, Laine H McCarthy
CLINICAL QUESTION: In menopausal women who experience regular hot flashes, does treatment with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) reduce the frequency and/or severity of hot flashes? ANSWER: Yes. Review of the literature suggests that treatment with SSRIs or SNRIs reduces the frequency and severity of hot flashes in menopausal and post-menopausal women. Studies demonstrated that paroxetine (Paxil), citalopram (Celexa) and escitolapram (Lexapro) were the most effective SSRIs, and venlafaxine (Effexor) was the most effective first line SNRI, with desvenlafaxine as a second option...
May 2017: Journal of the Oklahoma State Medical Association
https://www.readbyqxmd.com/read/28648570/brain-behavioral-adaptability-predicts-response-to-cognitive-behavioral-therapy-for-emotional-disorders-a-person-centered-event-related-potential-study
#20
Jonathan P Stange, Annmarie MacNamara, Amy E Kennedy, Greg Hajcak, K Luan Phan, Heide Klumpp
Single-trial-level analyses afford the ability to link neural indices of elaborative attention (such as the late positive potential [LPP], an event-related potential) with downstream markers of attentional processing (such as reaction time [RT]). This approach can provide useful information about individual differences in information processing, such as the ability to adapt behavior based on attentional demands ("brain-behavioral adaptability"). Anxiety and depression are associated with maladaptive information processing implicating aberrant cognition-emotion interactions, but whether brain-behavioral adaptability predicts response to psychotherapy is not known...
June 22, 2017: Neuropsychologia
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