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Pterygium

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https://www.readbyqxmd.com/read/29146761/comparison-among-adjuvant-treatments-for-primary-pterygium-a-network-meta-analysis
#1
Ellen Carrara Fonseca, Eduardo Melani Rocha, Gustavo Viani Arruda
PURPOSE: Pterygium is a frequent ocular disease, where the major challenge is the high level of recurrence after its surgical removal. We performed a network meta-analysis to identify, among several adjuvant treatments for primary pterygium, which is the best to prevent recurrence. METHODS: A search was conducted using PubMed, Scientific Electronic Library Online, Latin American and Caribbean Centre on Health Sciences and Cochrane Eyes and Vision Group Trials Register between 1993 and 2015 for randomisedclinical trials (RCTs) comparing adjuvant treatments following primary pterygium surgery...
November 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29135709/pilot-study-comparing-topical-anesthetic-agents-in-pterygium-surgery-subconjunctival-injection-versus-2-lidocaine-gel-versus-5-lidocaine-gel
#2
Felipe Pereira, Hélio Francisco Shiroma, Muller Gonçalves Urias, Verônica Haysa Yamada, Acácio Alves de Souza Lima, Ana Luisa Hofling-Lima, Michel Eid Farah, Eduardo Buchele Rodrigues
PURPOSE: To compare the efficacy of different concentrations of topical lidocaine gel with standard subconjunctival anesthesia. METHODS: This was a prospective randomized controlled pilot study with 3 different groups. Group SC received subconjunctival lidocaine and proparacaine drops as needed during surgery. Group L2 received 2% lidocaine gel and group L5 received 5% lidocaine gel. Both lidocaine gel groups could receive another gel dose as needed during the procedure...
November 13, 2017: Cornea
https://www.readbyqxmd.com/read/29131557/comparison-of-self-made-cryopreservative-fibrin-glue-and-commercial-fibrin-glue-kit-in-pterygium-surgery-1-year-follow-up
#3
Jingwen Gong, Jiaqi Fan, Ting Shen, Jin Jiang
PURPOSE: To assess long-term efficacy and safety of self-made cryopreservative fibrin glue (SMC) applied in pterygium surgery. METHODS: Prospective, comparative, interventional case series. Forty eyes of 40 patients with nasal primary pterygium, 24 male and 16 female, were enrolled. The patients were assigned to two groups and each contained 12 male and eight female based on the pterygium area encroaching onto the cornea. In one group, the conjunctival autograft was attached to the sclera with SMC stored for 2 months, and in the other group, commercial fibrin glue kit (CK) was applied after the pterygium was removed...
November 13, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29124395/non-invasive-detection-of-hpv-dna-in-exfoliative-samples-from-ophthalmic-pterygium-a-feasibility-study
#4
Αikaterini K Chalkia, Stavros Derdas, Georgios Bontzos, George Sourvinos, Εfstathios T Detorakis
PURPOSE: The evaluation of a non-invasive detection method for human papilloma virus (HPV) in ophthalmic pterygia. METHODS: Cotton swab samples and corresponding tissue specimens were collected from 21 ophthalmic pterygia of 21 patients. HPV detection and typing were performed by real-time PCR. Discrepancies in HPV detection between swab and tissue samples as well as clinical correlations of findings were examined. RESULTS: HPV DNA was detected in 9 (42...
November 9, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29096629/serratia-marcescens-endophthalmitis-after-pterygium-surgery-a-case-report
#5
Myeong Yeon Yi, Jin Kwon Chung, Kyung Seek Choi
BACKGROUND: To report a case of Serratia marcescens endophthalmitis after pterygium surgery using the bare sclera technique with mitomycin C (MMC). CASE PRESENTATION: A 69-year-old male patient underwent pterygium excision surgery using the bare sclera technique and 0.02% MMC. The patient presented with decreased visual acuity and pain from the day after the operation. Trans pars plana vitrectomy was performed and intravitreal antibiotics were administered. Cultures from the aqueous humor and intraocular lens were all positive for S...
November 2, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29086327/conjunctival-changes-in-different-clinical-variants-of-early-pseudoexfoliation
#6
Aparna Rao, Gopinath Das, Sarada Sarangi, Debananda Padhy
PURPOSE: To evaluate the conjunctival signs in different forms of pseudoexfoliation (PXF) syndrome to identify signs predicting early forms of the disease. METHODS: This observational study included patients with newly diagnosed PXF screened in the outpatient department of glaucoma services. Slit lamp photographs were captured in low and high magnification after full dilatation, and details like melanotic pigmentation, vascularity and tortuosity of vessels, scarring if any, presence of pterygium and actinic changes along with basal Schirmer's test were analysed...
October 30, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29080063/validity-of-a-new-comprehensive-pterygia-grading-scale-for-use-in-clinical-research-and-clinical-trial
#7
Ping Huang, Jianyan Huang, Tudor Tepelus, Jyotsna Maram, Srinivas Sadda, Olivia L Lee
PURPOSE: To determine the reliability and agreement of a new comprehensive pterygium grading scale for use in clinical research and clinical trials. METHODS: Thirty eyes with pterygia were enrolled in this study. Primary gaze position and lateral gaze position images were taken of each eye with a modified single-lens reflex camera system. Our grading scale includes five parameters: two hyperemia parameters of pterygia on two different gaze position images and three size parameters, quantifying length, width, and area of the cornea encroachment of pterygium, using ImageJ software...
October 27, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29079272/modulation-of-fibroblasts-in-conjunctival-wound-healing
#8
REVIEW
Mark Zada, Ushasree Pattamatta, Andrew White
Modulating conjunctival wound healing has the potential to improve outcomes after glaucoma filtration surgery and for several ocular disorders, including ocular cicatrial pemphigoid, vernal keratoconjunctivitis, and pterygium. Although anti-inflammatories and antimetabolites have been used with success, these nonspecific agents are not without their complications. The search for novel and more targeted means to control conjunctival fibrosis without such limitations has brought much attention to the regulation of fibroblast proliferation, differentiation, extracellular matrix production, and apoptosis...
October 24, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29053563/new-pterygium-surgical-techniques-require-standardization-of-outcome-measures
#9
Lawrence W Hirst
No abstract text is available yet for this article.
October 17, 2017: Cornea
https://www.readbyqxmd.com/read/29049722/a-ppar-gamma-agonist-rosiglitazone-suppresses-fibrotic-response-in-human-pterygium-fibroblasts-by-modulating-the-p38-mapk-pathway
#10
Selikem Abla Nuwormegbe, Joon Hyung Sohn, Sun Woong Kim
Purpose: Fibroblast activation may play an important role in pterygium progression. Synthetic peroxisome proliferator-activated receptor γ (PPAR-γ) ligands have been shown to be effective antifibrotic agents against transforming growth factor β1 (TGF-β1) induced fibrosis in several tissues. We aimed to investigate the antifibrotic effects of the PPAR-γ ligand rosiglitazone in pterygium fibroblasts and the underlying mechanisms. Methods: Profibrotic activation was induced by TGF-β1 in primary cultured human pterygium fibroblasts and the effect of rosiglitazone treatment on α-smooth muscle actin (α-SMA), and extra cellular matrix proteins synthesis was detected by western blotting, real-time PCR, immunostaining, and flow cytometry...
October 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29049230/goniosynechialysis-combined-with-cataract-extraction-for-iridoschisis-a-case-report
#11
Zhipeng You, Yan Qin, Guodong Li, Ke Shi
RATIONALE: Iridoschisis is a rare eye disease. In this case report, we described the examination and diagnosis of a case of iridoschisis accompanied by secondary glaucoma. We also observed the effects of treating the patient with a combination of goniosynechialysis and cataract removal. PATIENT CONCERN: A 67-year-old female patient presented with decreased vision in both eyes. An eye examination indicated that visual acuities (VAs) were 20/100 and light perception in the right and left eyes, respectively...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29044071/prevalence-of-spheroidal-degeneration-of-cornea-and-its-association-with-other-eye-diseases-in-tribes-of-western-rajasthan
#12
Amit Mohan, Zeeshan Jamil, Vishal C Bhatanagar, Manju Gajraj
PURPOSE: To determine the prevalence of spheroidal degeneration of cornea (SDC) and its association with other eye diseases in the tribes of South-West Rajasthan. METHODS: A total of 5012 patients were examined on slit lamp for the diagnosis of SDC. Diagnosis of SDC was made based on presence of amber granules in the superficial stroma of peripheral interpalpebral cornea with increasing opacification, coalescence and central spread or nodular and hazy surrounding stroma and divided in three stages...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29017515/low-recurrence-rate-of-anchored-conjunctival-rotation-flap-technique-in-pterygium-surgery
#13
Dong Ju Kim, Jimmy K Lee, Roy S Chuck, Choul Yong Park
BACKGROUND: To report the recurrence rate for an anchored conjunctival rotation flap technique in primary pterygium surgery. METHODS: Primary pterygium surgeries performed using anchored conjunctival rotation flap techniques (110 eyes in 110 patients) with a minimum follow-up of 12 months were reviewed. In this technique, a conjunctival flap is rotated to cover the bare sclera and suture-fixated with either 8-0 polyglactin (41 eyes) or 10-0 nylon (69 eyes). The recurrence rate was determined, and the two suture materials utilized were compared...
October 10, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28976415/amniotic-membrane-grafts-to-reduce-pterygium-recurrence
#14
Ronald Rosen
PURPOSE: To demonstrate the long-term outcome of pterygium surgery with adjunctive amniotic membrane transplantation (AMT) and intraoperative mitomycin C (MMC) in a large case series. METHODS: Medical records were retrieved for this noncomparative retrospective study of all patients who had pterygium excision with adjunctive AMT and intraoperative MMC, from October 2010 to June 2016 with at least 6 months of follow-up. RESULTS: There were a total of 556 eyes of 535 patients (291 males and 244 females) with average age of 51...
October 2, 2017: Cornea
https://www.readbyqxmd.com/read/28974213/short-term-in-vivo-morphological-changes-of-amniotic-membrane-after-fibrin-glue-assisted-pterygium-surgery-on-anterior-segment-optical-coherence-tomography-a-case-presentation
#15
Jun Hyuk Son, Su-Ho Lim
BACKGROUND: The evaluations of morphological changes of amniotic membrane (AM), even after successful AM transplantation surgery without complications, may be difficult. Moreover, there was no report regarding morphological changes after fibrin glue-assisted AM transplantation with pterygium excision. Here, we highlight and describe the use of spectral domain optical coherence tomography (OCT) for the evaluation of the morphological features of amniotic membrane (AM) and of associated in vivo structural changes after fibrin glue-assisted pterygium surgery...
October 3, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28969169/sutureless-glue-less-conjunctival-autograft-versus-conjunctival-autograft-with-sutures-for-primary-advanced-pterygia-an-interventional-pilot-study
#16
Tanie Natung, Avonuo Keditsu, Wakaru Shullai, Prasanta Kumar Goswami
INTRODUCTION: Conjunctival Autograft (CAG) in pterygium surgery can be attached by sutures or fibrin glue or autologous in situ blood coagulum. Recurrence rate and other parameters related to pterygium surgery between CAG with sutures and autologous in situ blood coagulum have not been compared uniformly in advanced pterygia alone. AIM: To compare and evaluate the outcome of sutureless, glue-less CAG with autologous in situ blood coagulum versus CAG with sutures for primary, advanced pterygium...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28960450/pterygium-inversum-unguis-secondary-to%C3%A2-gel-polish
#17
J Cervantes, M Sanchez, A E Eber, M Perper, A Tosti
BACKGROUND: Pterygium inversum unguis (PIU) is characterized by the abnormal adherence of the hyponychium to the ventral surface of the nail plate. It can be both unsightly and painful, resulting in morbidity for patients. Gel polish is a popular nail cosmetic that has been reported to cause several complications. PIU may be another adverse outcome. OBJECTIVE: To highlight a newly-recognized adverse effect of a popular beauty technique. METHODS: This retrospective and prospective case series reports 17 women who developed PIU after gel polish use...
September 28, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28954022/vitamin-d-level-in-patients-with-pterygium
#18
Necip Kara, Seda Ceri
Purpose: To evaluate blood vitamin D level in patients with pterygium. Methods: This prospective study, compared 58 eyes of 58 healthy individuals (control group) with 63 eyes of 63 patients with pterygium (study group). Subjects were stratified by time spent indoors or outdoors. Participants were given comprehensive ophthalmic examinations; blood 25-hydroxyvitamin D (nmol/L) was assayed. Results: Vitamin D level was significantly higher in men with pterygium than without it (p=0...
July 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28944207/predictive-factors-of-visual-outcome-of-malaysian-cataract-patients-a-retrospective-study
#19
Thanigasalam Thevi, Myron Anthony Godinho
AIM: To explore the associations between various characteristics of Malaysian cataract patients and their management, and their post-operative visual outcomes, to inform relevant bodies to reduce cataract-related blindness. METHODS: We conducted a descriptive secondary data analysis of cataract surgery patients in Melaka Hospital, from 2007 to 2014 using the National Eye Database (NED). Patient-related factors (demographic features, systemic and ocular comorbidities) and management-related factors (surgical duration, type of surgery, type of lens) were analysed for their association with visual outcome (acuity)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28944189/suppression-of-fibrosis-in-human-pterygium-fibroblasts-by-butyrate-and-phenylbutyrate
#20
Yuka Koga, Noriaki Maeshige, Hiroto Tabuchi, Mikiko Uemura, Michiko Aoyama-Ishikawa, Makoto Miyoshi, Chikako Katakami, Makoto Usami
AIM: To evaluate the antifibrogenic effects of butyrate or phenylbutyrate, a chemical derivative of butyrate, in human pterygium fibroblasts. METHODS: Human pterygium fibroblasts obtained from patient pterygium tissue were treated with butyrate or phenylbutyrate for 48h. Expression of α-smooth muscle actin, collagen I, collagen III and matrix metalloproteinase-1 mRNA was measured by quantitative real-time reverse transcription polymerase chain reaction, and acetylated histone was evaluated by Western blotting...
2017: International Journal of Ophthalmology
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