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Pterygium

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https://www.readbyqxmd.com/read/28524142/-effectiveness-of-epithelialization-therapy-after-surgical-treatment-of-pterygiu
#1
A V Petraevskiy, K S Trishkin, I A Gndoyan
Pterygium is widely distributed in regions with hot and dry climate. Frequent relapses of the disease are due to delayed epithelialization of postoperative corneal erosion, associated inflammation and formation of dry areas of the cornea. Effective stimulation of corneal epithelium regeneration in the postoperative period could reduce the frequency of relapses. AIM: to compare the effectiveness, safety and tolerability of different keratoprotectors in patients after surgical treatment of pterygium...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28522251/very-long-term-success-of-pterygium-surgery-with-conjunctival-graft
#2
Ofira Zloto, Nachum Rosen, Ari Leshno, Mordechai Rosner
PURPOSE: To examine to the very long term prognosis (16 years in average) of pterygium surgery with superior or inferior conjunctival graft. METHODS: Clinical data for patients that underwent pterygium surgery with conjunctival graft by two surgeons at the Goldschleger Eye Institute, Sheba Medical Center, Israel, between the years 1997-2001 were retrieved from medical records. For all the included patients, data about their eye examinations was summarized and a questionnaire about their eye history was done...
May 15, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28521845/hiv-infected-individuals-on-long-term-antiretroviral-therapy-are-at-higher-risk-for-ocular-disease
#3
E Schaftenaar, N S Khosa, G S Baarsma, C Meenken, J A McINTYRE, A D M E Osterhaus, G M G M Verjans, R P H Peters
Introduction of antiretroviral therapy (ART) has dramatically reduced the incidence of infectious ocular diseases in human immunodeficiency virus (HIV)-infected individuals. However, the effects of long-term ART and chronic HIV infection on the eye are ill-defined. This study determined the occurrence and severity of ocular diseases among 342 participants in a rural South African setting: HIV-naïve (n = 105), HIV-infected ART-naïve (n = 16), HIV-infected on ART for 36 months (long-term ART; n = 165). More HIV-infected participants presented with an external eye condition, in particular blepharitis, than HIV-naïve individuals (18% vs...
May 19, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28512421/when-an-easy-thing-goes-wrong-foreign-body-induced-granuloma-associated-scleritis-following-pterygium-surgery
#4
Pedro Coelho, Carlos Menezes, Pedro Rodrigues, Rita Gonçalves, Tiago Maio, Jorge Moreira, Paula Tenedório
PURPOSE: To report a case of pterygium surgery with conjunctival autograft followed by focal necrotizing scleritis due to foreign body entrapment in the scleral bed. CASE REPORT/RESULTS: This is a case report of a 76-years-old male patient who underwent nasal pterygium surgery and developed focal necrotizing scleritis secondary to foreign body entrapment under conjunctival autograft. One month following surgery, slit-lamp examination demonstrated a progressive thinning of the surgical area with focal inflammatory signs...
January 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28501948/corneal-tomography-and-biomechanics-in-primary-pterygium
#5
M Vanathi, Sahil Goel, Anita Ganger, Tushar Agarwal, T Dada, Sudarshan Khokhar
PURPOSE: To study the Scheimpflug's imaging and corneal biomechanics in primary pterygium. METHODS: A prospective observational study of 55 patients with unilateral primary nasal pterygium was done. The normal fellow eyes of patients with pterygium were taken as controls. Clinical parameters noted included visual acuity, values of corneal curvature by doing Scheimpflug imaging, wavefront aberrations in terms of higher and lower-order aberrations and corneal hysteresis (CH) as well as corneal resistance factor (CRF) values by using ocular response analyzer...
May 13, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28489723/femtosecond-laser-assisted-pterygium-surgery
#6
Matthias Fuest, Yu-Chi Liu, Minas T Coroneo, Jodhbir S Mehta
PURPOSE: Pterygium is a prevalent ocular surface disorder. Conjunctival autografting (CAG) after pterygium resection is the gold standard treatment. Thinner CAGs without Tenon tissue provide better results but are technically difficult to achieve. We report on the first femtosecond laser (FSL)-assisted pterygium surgery (FLAPS) in humans. METHODS: In a clinical trial, we treated 6 eyes of 5 patients with FLAPS. After manual removal of the pterygium, CAGs were dissected with the Ziemer Z8 at 60-μm depth and glued into the resection defect...
May 9, 2017: Cornea
https://www.readbyqxmd.com/read/28489720/expression-of-peroxiredoxin-2-and-vascular-endothelial-growth-factor-receptor-2-in-pterygium
#7
Yuchuan Wang, Jinyong Lin, Luxia Chen, Liming Wang, Peng Hao, Ruifang Han, Ming Ying, Xuan Li
PURPOSE: The expression of peroxiredoxin 2 and vascular endothelial growth factor receptor 2 (VEGFR2) was detected in pterygium to investigate whether they are involved in the pathogenesis or recurrence of pterygium and to evaluate the association between peroxiredoxin 2 and VEGFR2 in pterygium. METHODS: Ten normal bulbar conjunctivae, 35 primary pterygia, and 35 recurrent pterygia were obtained. Formalin-fixed, paraffin-wax-embedded tissues were analyzed by immunohistochemistry with peroxiredoxin 2 and VEGFR2 antibodies...
May 9, 2017: Cornea
https://www.readbyqxmd.com/read/28489563/efficacy-of-fibrin-glue-versus-sutures-for-attaching-conjunctival-autografts-in-pterygium-surgery-a-systematic-review-with-meta-analysis-and-trial-sequential-analysis-of-evidence
#8
Aihua Lan, Feifan Xiao, Yun Wang, Zhen Luo, Qixin Cao
Previous meta-analyses have been conducted to compare the efficacy of fibrin glue (FG) versus sutures in pterygium surgery; however, additional clinical trials have since been published. Therefore, we conducted an updated meta-analysis to further explore the association between FG application in pterygium surgery, and the recurrence rate, complication rate, and surgical duration. An electronic literature search for eligible studies published before July 29, 2016 was conducted across multiple databases. Odds ratios (ORs), standardized mean difference (SMD), and 95% confidence intervals (CI) were calculated...
April 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28478469/amniotic-membrane-transplantation-current-indications-in-a-tertiary-eye-hospital-of-eastern-nepal
#9
Diwa Hamal, Sanjay Kumar Singh, Binaya Lamichhane, Archana Sharma, Afaque Anwar, Vijay Mahaseth
INTRODUCTION: Amniotic membrane has unique properties that can be helpful to treat different ocular surface diseases. OBJECTIVES: To report our experience with 100% glycerol preserved amniotic membrane at 4°C and fresh amniotic membrane transplantation (AMT) with and without limbal graft for ocular surface reconstruction. MATERIALS AND METHODS: Retrospective case study of 211 eyes of 211 patients was conducted at Biratnagar Eye Hospital from June 2008 to March 2014...
July 2016: Nepalese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28468208/popliteal-pterygium-syndrome-with-syngnathia
#10
Andrea Sisti, Nicola Freda, Alessandro Giacomina, Gian Luca Gatti
Popliteal pterygium syndrome is a condition characterized by skin webs on the popliteal fossa, which may impair mobility unless surgically repaired. Affected individuals may also have syndactyly on the fingers and/or toes. Most people with this disorder present cleft lip and cleft palate and they can have syngnathia, that is a congenital adhesion between maxilla and mandible by fibrous bands, which affects the opening of the mouth. The case that we report is about a 2-month-old male, who presented skin webs bilaterally on the popliteal fossa, syndactyly between the IV and the V toe of the right foot and between the III and the IV toe of the left foot, and genital malformations...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28465659/comparison-of-fibrin-glue-and-vicryl-sutures-in-conjunctival-autografting-for-pterygium-surgery
#11
Xiu Wang, Yan Zhang, Lei Zhou, Ruihua Wei, Lijie Dong
PURPOSE: To compare clinical parameters and the tear levels of inflammatory cytokines between pterygium surgery using sutures or fibrin glue. METHODS: Fifty-six patients with primary pterygium were divided into the suture group and the glue group, in which the autograft was secured with 10-0 Vicryl sutures and fibrin glue, respectively. A questionnaire, slit-lamp examination, Schirmer test, and visual acuity test were performed in all participants. Real-time quantitative PCR (q-PCR) was used to analyze the expression of genes in pterygium and healthy conjunctival tissues...
2017: Molecular Vision
https://www.readbyqxmd.com/read/28450908/tailored-treatment-for-the-management-of-scleral-necrosis-following-pterygium-excision
#12
Linna Lu, Shiqiong Xu, Shengfang Ge, Chunyi Shao, Zi Wang, Xuyang Weng, Wenjuan Lu, Xinhua Wu, Yao Fu, Xianqun Fan
The present study aimed to investigate the efficacy of tailored treatment for the management of scleral necrosis following pterygium surgery. A series of nine cases of scleral necrosis following pterygium excision between September 2009 and September 2012 were included. In cases where ischemia was the cause of scleral necrosis, Tenon's membrane covering (TMC) surgery was performed. For cases with surgically-induced necrotizing scleritis (SINS), systemic immunosuppressive therapy following surgical repair of the scleral defect was administered in the form of oral prednisolone (starting dose, 30-60 mg/day)...
March 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28440253/evaluation-of-meibomian-gland-and-tear-film-changes-in-patients-with-pterygium
#13
Fen Ye, Fen Zhou, Yuan Xia, Xiaomin Zhu, Yan Wu, Zhenping Huang
BACKGROUND: Recent studies have demonstrated that pterygium has a close relationship with dry eye disease. This study is to determine abnormalities in meibomian gland and tear function in patients with pterygium and to assess the relationship between the variables. MATERIALS AND METHODS: Forty eyes from forty patients with primary nasal pterygium and forty eyes from forty volunteers without ocular pathologies were enrolled in this study. Ocular surface disease index scores, meibomian gland expression scores, lid margin abnormality scores, meiboscore, tear film breakup time (BUT), Schirmer test (SIT) value, and the lower tear meniscus height (TMH), tear meniscus depth (TMD), and tear meniscus area (TMA) using Fourier domain optical coherence were performed...
March 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28429128/endophthalmitis-associated-with-purpureocillium-lilacinum-during-infliximab-treatment-for-surgically-induced-necrotizing-scleritis-successfully-treated-with-27-gauge-vitrectomy
#14
Masaaki Yoshida, Shunji Yokokura, Hiroshi Kunikata, Naoko Takada, Kazuichi Maruyama, Masahiro Toyokawa, Kazushi Kashio, Mitsuo Kaku, Toru Nakazawa
PURPOSE: To report a case of endophthalmitis associated with Purpureocillium lilacinum (P. lilacinum) during infliximab treatment for surgically induced necrotizing scleritis, successfully treated with 27-gauge vitrectomy. METHODS: A single case report. RESULTS: A 71-year-old man who had undergone immunosuppressive therapy, including infliximab, for surgically induced necrotizing scleritis (SINS) in his left eye complained of visual disturbance and eye pain in the eye...
April 20, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28410726/surgical-techniques-and-adjuvants-for-the-management-of-primary-and-recurrent-pterygia
#15
REVIEW
John A Hovanesian, Christopher E Starr, David T Vroman, Francis S Mah, Jose A P Gomes, Marjan Farid, Neda Shamie, Richard S Davidson, Thomas John, Edward J Holland, Terry Kim
The removal and rate of recurrence of pterygium have been discussed for years. The disorder is highly associated with environmental factors, and recurrence rates can be unacceptably high and cannot be successfully predicted. New techniques and graft preparations and postoperative management strategies are helping to reduce the recurrence rates and provide an ocular surface that is near ideal for future cataract or refractive surgery. This review discusses the advantages and disadvantages of various treatment strategies...
March 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28410547/endocan-overexpression-in-pterygium
#16
Raşit Kiliç, Ali Kurt, Murat Tad, Sedat Taşdemir
PURPOSE: The aim of this study was to evaluate the possible role of endocan in the pathogenesis of pterygium. METHODS: The study was conducted on 33 patients with primary pterygium and 20 control subjects with normal bulbar conjunctiva. Patients with pterygium were graded into 3 groups as atrophic, fleshy, and intermediate, according to the Tan classification. Primary nasal pterygia and normal bulbar conjunctivas were surgically removed. Endocan expression was immunohistochemically investigated...
June 2017: Cornea
https://www.readbyqxmd.com/read/28406800/simple-limbal-epithelial-transplantation
#17
Virender S Sangwan, John A H Sharp
PURPOSE OF REVIEW: Simple limbal epithelial transplant (SLET) is a technique for addressing limbal stem cell deficiency. Limbal tissue from a donor eye, typically the patient's fellow healthy eye, is transplanted onto an amniotic membrane attached to the surface of the diseased eye. SLET was developed to address limitations of other techniques. Specifically, the technical difficulty of ex-vivo expansion of cells required in some techniques and the larger amount of valuable limbal tissue harvested in techniques not relying on ex-vivo expansion...
April 12, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28393179/efficacy-of-curcumin-in-inducing-apoptosis-and-inhibiting-the-expression-of-vegf-in-human-pterygium-fibroblasts
#18
Cheng-Wei Lu, Ji-Long Hao, Lei Yao, Hai-Jun Li, Dan-Dan Zhou
Pterygium is an inflammatory and degenerative ocular surface disease, in which the conjunctiva on the cornea grows to form a fibrous tissue in the shape of a triangle. Although pterygium surgery is used broadly in clinical practice, its high recurrence rate poses a great concern for patients and doctors. In the present study, we examined the effects of curcumin on the apoptosis and proliferation of human pterygium fibroblasts (HPFs) in an in vitro culture system. HPFs were incubated with curcumin for 24 to 72 h (5, 20, 80 or 200 µmol/l)...
May 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28385271/-ocular-complications-after-honeybee-sting-therapy-for-a-pterygium
#19
M R Ez-Zahraoui, M Y El Bakkouri, I Hajji, A Moutaouakil
No abstract text is available yet for this article.
May 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28368995/proposal-for-a-novel-severity-grading-system-for-pterygia-based-on-corneal-topographic-data
#20
Kazunori Miyata, Keiichiro Minami, Atsushi Otani, Tadatoshi Tokunaga, Shouta Tokuda, Shiro Amano
PURPOSE: To propose a grading system of pterygium severity based on corneal higher-order irregularity (HOI) and to evaluate postoperative changes in corneal irregularity of the graded pterygia. METHODS: In 268 eyes of 226 patients undergoing excision surgery of primary nasal pterygium, Placido corneal topography images were taken before and until 6 months after surgery. The best-corrected visual acuity (BCVA) and pterygium size with respect to the corneal diameter were also measured...
March 31, 2017: Cornea
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