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Rongxin Chen, Guofu Huang, Shu Liu, Wenfang Ma, Xiaofang Yin, Shiyou Zhou
PURPOSE: This study compared the outcomes of a limbal conjunctival autograft (LCAG) with those of an amniotic membrane graft (AMG) followed by intraoperative 0.02 % mitomycin C (MMC) to treat recurrent pterygium. METHODS: In this randomized controlled trial, ninety-six eyes with recurrent pterygium were enrolled and randomly allocated into two groups using a computer-generated random number table. Pterygium removal was followed by intraoperative 0.02 % MMC for 3 min and then either LCAG or AMG transplantation...
October 20, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Q F Liang, C Gao, H Liang, B Li, X H Du, Antoine Labbe
Objective: To observe the characteristics of pterygium with in vivo confocal microscopy (IVCM) and understand pterygium activity with the density of inflammatory cells, formation of new blood vessels, and the number of activated keratocytes within the stroma. Methods: A prospective case-controlled study. Thirty-six pterygia from 28 patients were analyzed in this study. A pterygium activity score was obtained by summing four scores of ocular discomfort, pterygium hyperemia, keratitis, and the presence of Fuchs patches...
October 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Linda Rose, Julia M Byrd, Yousuf Qaseem
IMPORTANCE: Currently the only treatment for recurrent pterygium is surgery. This is a phase 1 trial investigating ranibizumab as a medical treatment for recurrent pterygium. OBJECTIVE: To assess the safety and efficacy of subtenon Ranibizimab for recurrent pterygia. DESIGN: Subjects with recurrent pterygium received subtenon ranibizumab and were followed for 1 year. Safety parameters were measured. Photographs were taken and quantitatively analyzed to measure the short-term (2 months) and long-term (5-26 months) response to treatment...
October 7, 2016: Eye & Contact Lens
Koray Gumus, Aysegul Guven, Miray Altnkaynak, Merve Keskin
OBJECTIVES: The aim of this study was to compare different measurement tools and parameters, including a new computer-assisted image processing technique for the quantitative analysis of the percentage of pterygium on the corneal surface, horizontal/vertical lengths obtained using slitlamp beam and surgical compass. METHODS: A total of 21 pterygia of 17 patients were included in the study. The pterygia were measured by three different methods: a slitlamp beam, a surgical compass, and a new computer-assisted image processing method...
September 30, 2016: Eye & Contact Lens
Curtis R Cornelius
PURPOSE: Independent evaluation of efficacy of P.E.R.F.E.C.T. for PTERYGIUM technique in preventing recurrence after pterygium surgery. METHODS: Sixty consecutive cases of primary pterygium excision were performed between November 2006 and April 2012 using the P.E.R.F.E.C.T. for PTERYGIUM technique. RESULTS: Fifty-four (90%) cases were followed up for at least 1 year, and 58 (97%) were followed up for at least 6 months. There was 1 recurrence (1...
October 5, 2016: Cornea
Lawrence W Hirst, Katherine Smallcombe
PURPOSE: There are very few studies that describe the technique and results of double-headed pterygium removal and most of these have recurrence rates higher than those described for single pterygium removal. P.E.R.F.E.C.T for PTERYGIUM has a very low recurrence rate, and this study describes the recurrence rate and cosmesis when used on double-headed pterygia. METHODS: A prospective intervention series was performed on 20 eyes with a follow-up of 1 year or more with examination for recurrence and cosmetic appearance...
October 5, 2016: Cornea
Jeremy C K Tan, Melissa X Kuo, Minas T Coroneo
PURPOSE: To report on a case of autoconjunctival graft compromise after pterygium surgery in a patient on long-term anti-vascular endothelial growth factor (anti-VEGF) therapy, due to the deleterious effects of anti-VEGF agents on ocular wound healing. METHODS: A white female in her early eighties presented with large right nasal pterygium, first noted 5 years previously. She also had macular degeneration and had been receiving monthly injections of ranibizumab, which was later switched to aflibercept...
October 5, 2016: Cornea
Aihua Hou, Kai Pong Law, Min Qi Tin, Yoon Pin Lim, Louis Tong
Pterygium is a triangular shaped ocular fibrous surface lesion growing from conjunctiva towards central cornea, causing ocular irritation, astigmatism, and visual disturbance. The condition is characterized by epithelial proliferation, fibrovascular growth, chronic inflammation, and prominent extracellular matrix remodeling. Studies have suggested that aberrant extracellular proteins secreted by fibroblasts lead to abnormal matrix production and tissue invasion contributing to the development of the disease...
October 7, 2016: Experimental Eye Research
Dilek Hacıoğlu, Hidayet Erdöl
PURPOSE: To assess and compare the studies conducted in the literature with recurrence rates and the summary of the justified treatment approaches be presented. METHOD: Pterygium, a fibrovascular tissue that proceeds from the bulbar conjunctiva towards the cornea, is quite a commonly seen ocular surface deterioration. The treatment is performed through a surgical excision, and the frequent recurrence of this disorder, despite the developments of today, is the major problem experienced in the wake of the surgery...
September 23, 2016: International Ophthalmology
Kim Vieira Kayat, Paulo Elias Correa Dantas, Sérgio Felberg, Maria Antonieta Galvão, Mauro Ajaj Saieg
PURPOSE: Surface tumors of the eye comprise an ample spectrum of diseases with various clinical manifestations. Diagnosis has been traditionally achieved through core biopsies, but cytology is an innovative, fast, and minimally invasive method. The objective of this study was to investigate the use of exfoliative cytology as an alternative method for the detection of ocular surface squamous neoplasm (OSSN). METHODS: Exfoliative cytology of the lesions was performed by collecting smears using plastic brushes followed by smearing the cells onto slides and subsequently fixing them in 90% alcohol...
September 21, 2016: Cornea
A Hasegawa, T Murakoshi
No abstract text is available yet for this article.
September 2016: Ultrasound in Obstetrics & Gynecology
Suleyman Ciftci, Eyup Dogan, Umut Dag, Leyla Ciftci
PURPOSE: To describe a simple and effective technique for the prevention of pterygium recurrence. METHODS: This is a retrospective consecutive single-center case series with recurrence rate as the main outcome measure. Dissection of the conjunctiva, the Tenon's layer, and the sclera was continued up to the insertion of medial rectus. The exposed Tenon's layer was excised for 2 to 3 mm. The entire free edges of the conjunctiva was tacked firmly to the sclera. The conjunctival-limbal graft was sutured firmly to the sclera, recipient limbus, and to the conjunctiva incorporating the reciprocal edges...
September 9, 2016: International Ophthalmology
Takashi Ono, Yosai Mori, Ryohei Nejima, Tadatoshi Tokunaga, Kazunori Miyata, Shiro Amano
PURPOSE: To conduct a long-term follow-up study evaluating the efficacy and safety of transplantation of preserved limbal allograft and amniotic membrane for recurrent pterygium. METHODS: This was a retrospective, non-comparative, interventional case series conducted at a private eye hospital. Eighty-four eyes of 80 patients with recurrent pterygium were included in the study. The mean number of previous surgeries for pterygium was 1.36 ± 0.98 (range, 1-8)...
August 26, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Bojan Pajic, Iraklis Vastardis, Predrag Rajkovic, Brigitte Pajic-Eggspuehler, Daniel M Aebersold, Zeljka Cvejic
PURPOSE: Pterygium is a common lesion affecting the population in countries with high levels of ultraviolet exposure. The final shape of a pterygium is the result of a growth pattern, which remains poorly understood. This manuscript provides a mathematical analysis as a tool to determine the shape of human pterygia. MATERIALS AND METHODS: Eighteen patients, all affected by nasal unilateral pterygia, were randomly selected from our patient database independently of sex, origin, or race...
2016: Clinical Ophthalmology
Guy Lin, Tal Marom, David Dagan, Merin Ofer
OBJECT: The massive typhoon Haiyan (Yolanda) ripped across the central Philippines on November 8, 2013, and damaged infrastructure including hospitals. The Israeli Defense Forces field hospital was directed by the Philippine authorities to Bogo City in the northern part of the island of Cebu, to assist the damaged local hospital. Hundreds of patients with neglected diseases sought for medical treatment which was merely out of reach for them. Our ethical dilemmas were whether to intervene, when the treatment we could offer was not the best possible...
August 19, 2016: World Journal of Surgery
S M I Bukhari, K Y Kiu, R Thambiraja, S Sulong, A H G Rasool, A T Liza-Sharmini
PurposeThe role of microvascular endothelial dysfunction on severity of primary open angle glaucoma (POAG) was investigated in this study.Patients and methodsA prospective cohort study was conducted. One hundred and fourteen ethnically Malay patients (114 eyes) with POAG treated at the eye clinic of Hospital University Sains Malaysia between April 2012 and December 2014 were recruited. Patients aged between 40 and 80 years with two consecutive reliable and reproducible Humphrey visual field 24-2 analyses were selected...
August 19, 2016: Eye
Mohammad Reza Shayegan, Mohammad Reza Khakzad, Hamid Gharaee, A-Reza Varasteh, Mojtaba Sankian
BACKGROUND: The exact pathogenesis of pterygium is still not fully understood. Growth factors are considered to play an important role in the formation of pterygium. Transforming growth factor (TGF)-β1 is considered to be one of the main mediators of fibroblast stimulation and tissue remodeling in allergic conditions. The objective of the present study was to investigate the association between TGF-β1 gene expression and pterygium in atopic and nonatopic participants. METHODS: We used questionnaires to record demographic and clinical information from patients who underwent pterygium excision surgery...
October 2016: Journal of the Chinese Medical Association: JCMA
Kosol Kampitak, Wichai Leelawongtawun, Supinda Leeamornsiri, Wannisa Suphachearaphan
PURPOSE: To determine whether artificial tears can reduce recurrence of pterygium after surgery. METHODS: A total of 128 primary pterygium cases after excision were randomized into two groups according to postoperative drugs: 64 cases received topical dexamethasone (control group), and 64 cases received topical dexamethasone and hydroxypropyl methylcellulose (treatment group). The pterygium was removed with amniotic membrane graft technique in all cases. Recurrence was observed within 6 months after surgery, and survival analysis was used to evaluate the difference between groups...
August 13, 2016: Acta Ophthalmologica
Yeşim Altay, Özgür Balta
BACKGROUND/AIM: To compare the effectiveness of intraoperative 5 fluorouracil (5-FU) and mitomycin C (MMC) application in preventing recurrence following primary pterygium excision. MATERIALS AND METHODS: This was a prospective clinical trial that included 93 patients with primary pterygia assigned to three treatment groups in which 29 patients received an intraoperative application of 25 mg/mL 5-FU for 5 min, 32 patients received an intraoperative application of 0...
2016: Turkish Journal of Medical Sciences
Kofi Asiedu, Samuel Kyei, Benedict Ayobi, Frank Okyere Agyemang, Reynolds Kwame Ablordeppey
PURPOSE: This study sought to provide an evidence-based profile of the diagnosis, treatment and knowledge or opinions on dry eye among optometrists and ophthalmologists in Ghana. METHODS: This was a cross-sectional survey RESULTS: The responses of 162 participants are included in the analysis. The most commonly used test to diagnosed dry eye disease was tear break-up time followed by patient history. The most common symptom doctors heard from dry eye patients were burning sensation followed by foreign body sensation...
August 6, 2016: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
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