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Pterygium

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https://www.readbyqxmd.com/read/28106240/comparison-of-4-techniques-for-limbal-conjunctival-autograft-fixation-in-primary-pterygium-surgery
#1
Luis F Mejía, Juan P Santamaría, Miguel Cuevas, Andrea Córdoba, Sergio A Carvajal
PURPOSE: To compare 4 limbal-conjunctival autograft fixation techniques-conventional suture, commercial fibrin glue, autologous fibrin glue, and cautery-in primary nasal pterygium surgery. METHODS: This is a retrospective and descriptive study. The postoperative patient discomfort, graft edema, ocular inflammation, and other complications of 4 limbal-conjunctival autograft fixation techniques in primary nasal pterygium surgery were evaluated. RESULTS: Postoperative patient discomfort was significantly lower with the sutureless techniques (p<0...
January 18, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28105011/coincidence-of-inflamed-conjunctival-carcinoma-in-situ-and-primary-pterygium
#2
Hiroaki Endo, Satoru Kase, Yasuo Suzuki, Manabu Kase
BACKGROUND: We report a rare case of carcinoma in situ (CIS) in conjunction with a primary pterygium that exhibited characteristic angiographic and histopathological findings. CASE: A 78-year-old man presented with a pterygium and a whitish tumor adjacent to the pterygium in his right eye. Indocyanine green angiography displayed that feeder vessels within the primary pterygium spread to the whitish tumor. The tumor and pterygial tissues were surgically removed. Histologically, the resected tissue contained CIS as well as squamous metaplasia...
September 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28095564/successful-treatment-of-traumatic-onychodystrophy-and-associated-pterygium-unguis-with-fractionated-carbon-dioxide-laser-case-report-and-review-of-the-literature
#3
Derek Ho, Andrew Mamalis, Jared Jagdeo
Onychodystrophy is a common, chronic malformation of the nail that is aesthetically displeasing and can signi cantly impact patient quality-of-life. Onychodystrophy can be associated with pterygium unguis that contributes to pain and appears as a V-shaped exten- sion of the proximal nail fold skin. Treatment options are limited, and topical or intralesional corticosteroids have minimal ef cacy and cause signi cant patient discomfort. Surgical revision of onychodystrophy is complex, and symptomatic or aesthetic improvements are difficult to achieve...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28079693/conjunctival-autograft-versus-amniotic-membrane-transplantation-following-double-pterygium-excision-a-randomized-trial
#4
Venkatesh N Prajna, Lumbini Devi, Suganya K Seeniraj, Jeremy D Keenan
No abstract text is available yet for this article.
January 11, 2017: Cornea
https://www.readbyqxmd.com/read/28068383/inhibition-of-pterygium-fibroblast-migration-and-outgrowth-by-bevacizumab-and-cyclosporine-a-involves-down-regulation-of-matrix-metalloproteinases-3-and-13
#5
Yeoun-Hee Kim, Jae-Chang Jung, Sang Il Gum, Su-Bin Park, Jin Yeul Ma, Yong Il Kim, Kyoo Won Lee, Young Jeung Park
We examined the connection between matrix metalloproteinase (MMP) expression/activity and pterygium fibroblast migration, and how these were affected by bevacizumab and/or cyclosporine A (CsA). Fibroblasts were obtained from 20 pterygia and 6 normal conjunctival specimens. Expression levels of MMP-3 and MMP-13 were examined after bevacizumab administration. Immunofluorescence staining was used to examine expression of both MMPs in fibroblasts migrating out from explanted pterygium tissues. Rates of cell migration from explant-cultured pterygia tissues and scratch-wounded confluent pterygium fibroblasts were examined in the presence of MMP-3 or MMP-13 inhibitors, as well as bevacizumab and/or CsA...
2017: PloS One
https://www.readbyqxmd.com/read/28028964/genetic-factors-in-selected-complex-congenital-malformations-with-cleft-defect
#6
REVIEW
Piotr Wójcicki, Maciej J Koźlik, Karolina Wójcicka
Cleft lips, alveolar ridges and palates are among the most common birth defects. There are over 500 different complex genetic disorders that include cleft defects. The most common related defects include abnormalities of the skeleton, skull, cardiovascular and nervous system. The occurrence of a cleft results from the interplay of multiple genes and environmental factors. Several thousand different mutations responsible for these syndromes have been discovered, whereas there are still numerous phenotypic cases of unknown genetic origin...
September 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28018148/epigenetics-and-common-ophthalmic-diseases
#7
REVIEW
Wendy Li, Ji Liu, Jennifer A Galvin
The study of ocular diseases and epigenetic dysregulation is an emerging area of research. The knowledge from the epigenetic mechanisms of DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs regarding the pathogenesis of ocular diseases will be helpful for improved treatment modalities for our patients. In particular, we focus upon the how epigenetic regulatory mechanisms impact five common ocular diseases: age related macular degeneration, age-related cataract, pterygium, retinoblastoma, and uveal melanoma...
December 2016: Yale Journal of Biology and Medicine
https://www.readbyqxmd.com/read/28012607/do-demodex-mites-play-a-role-in-pterygium-development
#8
Witold Tarkowski, Joanna Moneta-Wielgoś, Daniel Młocicki
Numerous reports point to Demodex mites as the aetiology of certain eye and skin conditions, hence it is highly probable that infestation with these mites may also play a role in the aetiology and pathogenesis of pterygium. Therefore here we present a hypothesis: whether the presence of Demodex mites in eyelash hair follicles significantly correlates with the presence of pterygia, which could point to a potential role of these mites in the development of such lesions. We present preliminary data for supporting this hypothesis...
January 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28010889/nail-involvement-in-systemic-sclerosis
#9
Isabelle Marie, Vincent Gremain, Kladoum Nassermadji, Laetitia Richard, Pascal Joly, Jean-François Menard, Hervé Levesque
BACKGROUND: Nail involvement has rarely been recognized in systemic sclerosis (SSc). Indeed, only a few small series have assessed nail changes in SSc, most of which are case reports. OBJECTIVE: The aims of the current case-control study were to: (1) determine the prevalence of fingernail changes in SSc; and (2) evaluate the correlation between fingernail changes and other features of SSc. METHODS: In all, 129 patients with SSc and 80 healthy control subjects underwent routine fingernail examination...
December 20, 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28005757/correction-of-pterygium-colli-in-turner-syndrome-a-clinical-report-and-review-of-the-surgical-management
#10
Richard Ben Lou, Petros Konofaos, Robert D Wallace
The aim of surgery for pterygium colli (PC) is to correct the contour deformity, redistribute or remove the horizontal excess of skin, address the abnormal posterior hairline, avoid excessive scarring, and prevent recurrence. The purpose of this study is to review the available methods to correct the deformity and highlight a recent patient performed by the senior author. A modified bilateral Z-plasty technique was used for correcting PC on a 5-year-old African American girl diagnosed with Turner syndrome. The patient had an uneventful postoperative period and satisfactory functional and esthetic results were demonstrated at 1 year follow-up...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27994814/bilateral-photic-maculopathy-following-pterygium-excision-spectral-domain-optical-coherence-tomography-findings
#11
Mohammad Hossein Jabbarpoor Bonyadi
PURPOSE: To report high resolution spectral domain optical coherence tomography (SD-OCT) findings in a case with bilateral photic maculopathy and resultant central scotoma following pterygium excision. CASE REPORT: A 38-year-old man with a history of pterygium excision complained of visual disturbance and annoying central scotoma in both eyes. Although he had subtle funduscopic and angiographic changes, SD-OCT precisely showed disruption of the photoreceptors inner segment/outer segment in the foveal center...
October 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27987045/continuous-fetal-head-flexion-as-a-marker-for-prenatal-diagnosis-of-lethal-multiple-pterygium-syndrome-a-case-report
#12
Akihiro Hasegawa, Mieko Hanaoka, Takeshi Murakoshi
Lethal multiple pterygium syndrome (LMPS) is a fatal hereditary disease associated with abnormalities such as pterygium-induced congenital contractures. Fetal hydrops is present in more than half of all patients with LMPS, and all patients with LMPS are either stillborn or die in the early neonatal period. Ultrasonography findings for the prenatal diagnosis of LMPS include the detection of cutaneous webbing at multiple joints, multiple joint contractures, absent limb movement, and increased nuchal translucency...
December 16, 2016: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/27982218/management-of-necrotizing-scleritis-after-pterygium-surgery-with-rituximab
#13
Tania Sales de Alencar Fidelix, Luis Antonio Vieira, Virginia Fernandes Moca Trevisani
The authors present a case of necrotizing scleritis after pterygium excision successfully treated with rituximab after attempts with high doses of corticosteroids and immunosuppressive drugs. A literature review revealed case reports and a phase I/II dose-ranging randomized clinical trial using rituximab for necrotizing scleritis with or without association with autoimmune disease. This is the only case report on rituximab treatment for necrotizing scleritis after pterygium surgery. In cases with refractoriness to immunosuppressive drugs, a CD20 antibody can be used...
September 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/27977614/association-between-pterygium-and-obesity-status-in-a-south-korean-population
#14
Ga Eun Nam, Seonjoo Kim, Ji-Sun Paik, Hyun-Seung Kim, Kyung-Sun Na
This study examined the association between pterygium and obesity status by examining a nationally representative sample of South Korean adults.This population-based, cross-sectional study comprised 16,234 adults (aged ≥19 years) who had participated in the fifth annual Korea National Health and Nutrition Examination Survey from 2010 to 2012. The enrolled subjects underwent interviews, clinical examinations, and laboratory investigations. We compared body mass index (BMI) and waist circumference (WC), according to the presence of pterygium...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27956289/pterygium-size-and-effect-on-intraocular-lens-power-calculation
#15
Mustafa Koc, Mehmet Murat Uzel, Emre Aydemir, Fuat Yavrum, Pinar Kosekahya, Pelin Yılmazbaş
PURPOSE: To evaluate the effects of pterygium on biometry measurements and the relationship between these effects and pterygium size. SETTING: Ulucanlar Eye Hospital, Ankara, Turkey. DESIGN: Prospective comparative study. METHODS: Patients who had unilateral primary pterygium excision were included in the study group. Anterior segment photographed images were taken of eyes with pterygia to calculate the pterygium length and area using the ImageJ program...
November 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27941383/autologous-blood-versus-fibrin-glue-in-pterygium-excision-with-conjunctival-autograft-surgery
#16
Gaayathri Nadarajah, Vanitha Hema Ratnalingam, Hazlita Mohd Isa
PURPOSE: To evaluate graft stability and recurrence rate between fibrin glue and autologous blood in pterygium conjunctival autograft surgery. METHODS: A prospective, randomized, single-blinded clinical trial to assess the efficacy of autologous blood in place of fibrin glue in pterygium surgery. A total of 120 eyes of 111 patients were randomized according to pterygium morphology, to undergo pterygium surgery with autografting using either autologous blood or fibrin glue...
December 8, 2016: Cornea
https://www.readbyqxmd.com/read/27938950/pterygium-excision-with-conjunctival-autograft-and-subconjunctival-amniotic-membrane-as-antirecurrence-agents
#17
Alexander Shusko, John A Hovanesian
OBJECTIVE: To determine the outcome of pterygium excision with a conjunctival autograft when the adjunctive use of a subconjunctival graft of amniotic membrane is employed to reduce fibrosis and recurrence after surgery. DESIGN: This is a retrospective, noncomparative study of postoperative outcomes. PARTICIPANTS: Eighty-four patients totalling 101 eyes with clinically significant pterygia that warranted surgical excision. METHODS: Surgeries were performed at South Orange County Outpatient Surgery Center (San Clemente, Calif...
December 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27938948/effect-of-transverse-conjunctival-advancement-flap-surgery-for-primary-pterygium
#18
Jongyeop Park, Yengwoo Son, Eoksoo Suh
OBJECTIVE: To introduce a new surgical technique, transverse conjunctival advancement flap, and to evaluate the efficacy and safety of the technique in primary pterygium surgery. DESIGN: Retrospective, noncomparative, interventional case-series analysis. PARTICIPANTS: Sixty-three eyes of 63 patients. METHODS: The patients with primary pterygium were treated with transverse conjunctival advancement flap technique. After excision of the pterygium head and the perilimbal part of the pterygium body (within 2 mm from the limbus), the bare sclera was covered with the transverse conjunctival advancement flap using the conjunctiva of the remaining posterior part of the pterygium body...
December 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27935054/damaging-effects-of-ultraviolet-radiation-on-the-cornea
#19
Naomi C Delic, J Guy Lyons, Nick Di Girolamo, Gary M Halliday
The cornea sits at the anterior aspect of the eye and additionally to the skin, is highly exposed to ultraviolet radiation (UVR). The cornea blocks a significant proportion of UVB from reaching the posterior structures of the eye. However, UVA can penetrate the full thickness of the cornea, even reaching the anterior portion of the lens. Epidemiological data indicate that UVR is a contributing factor for a multitude of corneal diseases of the cornea including pterygium, photokeratitis, climatic droplet keratopathy, (CDK) and ocular surface squamous neoplasia (OSSN), although the pathogenic mechanisms of each require further elucidation...
December 9, 2016: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/27919798/femtosecond-laser-assisted-conjunctival-autograft-preparation-for-pterygium-surgery
#20
REVIEW
Matthias Fuest, Yu-Chi Liu, Gary Hin-Fai Yam, Ericia Pei Wen Teo, Hla Myint Htoon, Minas T Coroneo, Jodhbir S Mehta
PURPOSE: Pterygium is a common ocular surface disorder. Conjunctival autografting (CAG) following pterygium resection is the gold standard treatment. CAGs without Tenon's tissue provide better results but are more technically difficult to achieve. In this study, we evaluated the feasibility and reproducibility of femtosecond laser (FSL)-assisted CAG preparation. METHODS: Fifteen porcine globes were fixed in a suction holder and CAGs of different diameters were created by 1) an experienced consultant and 2) a less experienced fellow using the Ziemer LDV Z8...
December 2, 2016: Ocular Surface
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