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https://www.readbyqxmd.com/read/28813423/health-needs-and-care-seeking-behaviours-of-yazidis-and-other-minority-groups-displaced-by-isis-into-the-kurdistan-region-of-iraq
#1
Valeria Cetorelli, Gilbert Burnham, Nazar Shabila
BACKGROUND: During the summer of 2014, ISIS overran Nineveh governorate in Northern Iraq. Yazidis and other religious minorities were subjected to brutal attacks and forced to seek refuge into the neighbouring Kurdistan Region, where they remain living in local communities or in camps. This survey provides a population-based assessment of the health needs and care seeking behaviours of Yazidis and other groups currently residing in camps. METHODS: The survey covered 13 camps managed by the Kurdish Board of Relief and Humanitarian Affairs...
2017: PloS One
https://www.readbyqxmd.com/read/28810921/the-role-of-whole-body-computed-tomography-in-the-diagnosis-of-thoracic-injuries-in-severely-injured-patients-a-retrospective-multi-centre-study-based-on-the-trauma-registry-of-the-german-trauma-society-traumaregister-dgu-%C3%A2
#2
Patricia Lang, Martin Kulla, Fabian Kerwagen, Rolf Lefering, Benedikt Friemert, Hans-Georg Palm
BACKGROUND: Thoracic injuries are a leading cause of death in polytrauma patients. Early diagnosis and treatment are of paramount importance. Whole-body computed tomography (WBCT) has largely replaced traditional imaging techniques such as conventional radiographs and focused computed tomography (CT) as diagnostic tools in severely injured patients. It is still unclear whether WBCT has led to higher rates of diagnosis of thoracic injuries and thus to a change in outcomes. METHODS: In a retrospective study based on the trauma registry of the German Trauma Society (TraumaRegister DGU(®)), we analysed data from 16,545 patients who underwent treatment in 59 hospitals between 2002 and 2012 (ISS ≥ 9)...
August 15, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/28794243/malpractice-claims-related-to-diagnostic-errors-in-the-hospital
#3
Ashwin Gupta, Ashley Snyder, Allen Kachalia, Scott Flanders, Sanjay Saint, Vineet Chopra
BACKGROUND: Little is known about the incidence or significance of diagnostic error in the inpatient setting. We used a malpractice claims database to examine incidence, predictors and consequences of diagnosis-related paid malpractice claims in hospitalised patients. METHODS: The US National Practitioner Database was used to identify paid malpractice claims occurring between 1 January 1999 and 31 December 2011. Patient and provider characteristics associated with paid claims were analysed using descriptive statistics...
August 9, 2017: BMJ Quality & Safety
https://www.readbyqxmd.com/read/28791891/the-economic-burden-of-urinary-tract-infection-and-pressure-ulceration-in-acute-traumatic-spinal-cord-injury-admissions-evidence-for-comparative-economics-and-decision-analytics-from-a-matched-case-control-study
#4
Barry White, Nicolas Dea, John Street, Christiana L Cheng, Carly S Rivers, Najmedden Attabib, Brian K Kwon, Charles G Fisher, Marcel F Dvorak
Secondary complications of spinal cord injury (SCI) are a burden to afflicted individuals and the rest of society. However, there is limited evidence of the economic burden or cost of complications in SCI populations in Canada, which is necessary for comparative economic analyses and decision analytic modeling of possible solutions to these common health problems. Comparative economic analyses can inform resource allocation decisions, but the outputs are only as good as the inputs. In this article, new evidence of the excess or incremental costs of urinary tract infection (UTI) and pressure ulceration (PU) in acute traumatic SCI from an exploratory case series analysis of admissions to a Level I specialized Canadian spine facility (2008-2013) is presented...
August 9, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28789802/fatalities-from-a-greek-burn-unit-a-clinicopathological-correlation-of-129-cases
#5
Myron Tsagkarakis, Georgia-Alexandra Spyropoulou, Leonidas Pavlidis, Othon Kritikos, Nikolaos Karakoukis, Evgenia Kyriopoulos, Dimosthenis Tsoutsos
INTRODUCTION: This is a retrospective study of the hospital data and autopsy reports of burn patients who died in the Burn Unit of the Department of Plastic and Reconstructive Surgery, Microsurgery and Burn Center of "G. Gennimatas" Hospital of Athens, Greece during the period 1999-2005. MATERIALS AND METHODS: The records of the burn victims deceased during the period 1999-2005 were reviewed and the cause of injury, percentage of body surface area (BSA) burned, age, gender, and co-morbidities were documented...
August 5, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28789652/exploring-the-relationship-between-general-practice-characteristics-and-attendance-at-walk-in-centres-minor-injuries-units-and-emergency-departments-in-england-2009-10-2012-2013-a-longitudinal-study
#6
Peter Tammes, Richard W Morris, Emer Brangan, Kath Checkland, Helen England, Alyson Huntley, Daniel Lasserson, Fiona MacKichan, Chris Salisbury, Lesley Wye, Sarah Purdy
BACKGROUND: The UK National Health Service Emergency Departments (ED) have recently faced increasing attendance rates. This study investigated associations of general practice and practice population characteristics with emergency care service attendance rates. METHODS: A longitudinal design with practice-level measures of access and continuity of care, patient population demographics and use of emergency care for the financial years 2009/10 to 2012/13. The main outcome measures were self-referred discharged ED attendance rate, and combined self-referred discharged ED, self-referred Walk-in Centre (WiC) and self-referred Minor Injuries Unit (MIU) attendance rate per 1000 patients...
August 8, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28782658/patterns-of-treatment-of-accidental-genital-trauma-in-girls
#7
Tazim Dowlut-McElroy, Jeanette Higgins, Karen B Williams, Julie L Strickland
STUDY OBJECTIVE: To evaluate the characteristics of girls with accidental genital trauma (AGT) who can be managed in the emergency department (ED) versus the operating suite (OS). DESIGN: Retrospective cohort. SETTING: ED at a children's hospital in a metropolitan area. PARTICIPANTS: Girls aged 0 to 18 years with AGT. MAIN OUTCOME MEASURES: Factors associated with need for evaluation and repair of AGT in the OS...
August 3, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28780771/low-molecular-weight-heparin-for-prevention-of-venous-thromboembolism-in-patients-with-lower-limb-immobilization
#8
REVIEW
Aniek Ag Zee, Kelly van Lieshout, Maaike van der Heide, Loes Janssen, Heinrich Mj Janzing
BACKGROUND: Immobilization of the lower limb is a risk factor for venous thromboembolism (VTE). Low molecular weight heparins (LMWHs) are anticoagulants, which might be used in adult patients with lower-limb immobilization to prevent deep venous thrombosis (DVT) and its complications. This is an update of the review first published in 2008. OBJECTIVES: To assess the effectiveness of low molecular weight heparin for the prevention of venous thromboembolism in patients with lower-limb immobilization in an ambulatory setting...
August 6, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28776641/the-great-divide-country-of-birth-as-a-risk-factor-for-obstetric-anal-sphincter-injuries
#9
James Brown, Supuni Kapurubandara, Emma Gibbs, Jennifer King
BACKGROUND: Obstetric anal sphincter injuries (OASIS) can complicate up to 6% of births and are a major contributor to preventable maternal morbidity. Asian women have a risk of third and fourth degree perineal tears up to four times greater than women of other ethnicities in the same community, but the lack of differentiation of Asian women into regional groups has limited insight into the reasons behind their increased risk. AIMS: To investigate risk of OASIS associated with country of birth...
August 4, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28768055/harnessing-cxcr4-antagonists-in-stem-cell-mobilization-hiv-infection-ischemic-diseases-and-oncology
#10
REVIEW
Lun Kelvin Tsou, Ying-Huey Huang, Jen-Shin Song, Yi-Yu Ke, Jing-Kai Huang, Kak-Shan Shia
CXCR4 antagonists (e.g., Plerixafor(TM) ) have been successfully validated as stem cell mobilizers for peripheral blood stem cell transplantation. Applications of the CXCR4 antagonists have heralded the era of cell-based therapy and opened a potential therapeutic horizon for many unmet medical needs such as kidney injury, ischemic stroke, cancer, and myocardial infarction. In this review, we first introduce the central role of CXCR4 in diverse cellular signaling pathways and discuss its involvement in several disease progressions...
August 2, 2017: Medicinal Research Reviews
https://www.readbyqxmd.com/read/28765755/airway-support-using-a-pediatric-intubation-tube-in-adult-patients-with-atrial-fibrillation-a-simple-and-unique-method-to-prevent-heart-movement-during-catheter-ablation-under-continuous-deep-sedation
#11
Masateru Takigawa, Atsushi Takahashi, Taishi Kuwahara, Kenji Okubo, Emiko Nakashima, Yuji Watari, Kazuya Yamao, Jun Nakajima, Yasuaki Tanaka, Katsumasa Takagi, Shigeki Kimura, Hiroyuki Hikita, Kenzo Hirao, Mitsuaki Isobe
BACKGROUND: The present study aimed to elucidate the safety and effectiveness of a noble and unique airway management technique in which a pediatric intubation tube is used in adult patients with atrial fibrillation (AF) undergoing catheter ablation (CA) under continuous deep sedation. METHODS: In total, 246 consecutive patients with AF (mean age, 65±10 years; 60 women) underwent CA under dexmedetomidine-based continuous deep sedation. A 4-mm pediatric intubation tube guided by a 10-French intratracheal suction tube was inserted smoothly, and the tip of the tube was located at the base of the epiglottis...
August 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28761671/predictors-and-clinical-implication-of-high-sensitivity-cardiac-troponin-i-elevation-following-diagnostic-cardiac-catheterisations
#12
Rikuta Hamaya, Taishi Yonetsu, Tadashi Murai, Yoshihisa Kanaji, Eisuke Usui, Junji Matsuda, Masahiro Hoshino, Makoto Araki, Masahiro Hada, Takayuki Niida, Sadamitsu Ichijo, Yoshinori Kanno, Tsunekazu Kakuta
OBJECTIVES: Although diagnostic coronary angiography (CAG) is performed worldwide, procedure-related myocardial necrosis (PMN) following diagnostic catheter-based procedures has not been well investigated. The aim of this study was to determine clinical and procedural factors associated with PMN, using a high-sensitivity cardiac troponin I (hs-cTnI) assay, and to investigate the clinical implications of PMN. METHODS: Among 697 patients undergoing elective CAG and pre- and post-procedural hs-cTnI (pre-TnI, post-TnI, respectively) measurements, a total of 538 patients (124 female) were evaluated, with 2...
2017: Open Heart
https://www.readbyqxmd.com/read/28759324/non-suicidal-self-injury-sexuality-concerns-and-emotion-regulation-among-sexually-diverse-adolescents-a-multiple-mediation-analysis
#13
Gloria Fraser, Marc Stewart Wilson, Jessica Anne Garisch, Kealagh Robinson, Madeleine Brocklesby, Tahlia Kingi, Angelique O'Connell, Lynne Russell
Objectives Despite increasing interest in the prevalence and correlates of Non-Suicidal Self-Injury (NSSI) in adolescent populations, relatively few studies have examined NSSI among lesbian, gay and bisexual (LGB) adolescents. The current study explored sexuality concerns and elevated emotion dysregulation as potential mechanisms underlying the relationship between sexual orientation elevated non-suicidal self-injury (NSSI). Methods A community sample of 1799 adolescents completed a questionnaire assessing NSSI, sexual orientation, sexuality concerns, and emotion regulation...
July 31, 2017: Archives of Suicide Research: Official Journal of the International Academy for Suicide Research
https://www.readbyqxmd.com/read/28757688/ocular-trauma-a-tertiary-hospital-experience-from-oman
#14
Haitham H Al-Mahrouqi, Naila Al-Harthi, Maryam Al-Wahaibi, Kishore Hanumantharayappa
PURPOSE: To describe the epidemiology of ocular trauma in a tertiary hospital setting in Muscat, Oman. METHODS: Medical records of all cases of ocular trauma which presented to the Emergency Department at Al-Nahdha Hospital and were seen by the ophthalmology service from January 1, 2013 to June 30, 2013 (6 months) were reviewed to collect data on ocular trauma according to the World Eye Injury Registry initial reporting form which uses the Birmingham Eye Trauma Terminology System...
May 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/28755387/bdnf-genotype-is-associated-with-hippocampal-volume-in-mild-traumatic-brain-injury
#15
J P Hayes, A Reagan, M W Logue, S M Hayes, N Sadeh, D R Miller, M Verfaellie, E J Wolf, R E McGlinchey, W P Milberg, A Stone, S A Schichman, M W Miller
The negative long-term effects of mild traumatic brain injury (mTBI) have been a growing concern in recent years, with accumulating evidence suggesting that mTBI combined with additional vulnerability factors may induce neurodegenerative-type changes in the brain. However, the factors instantiating risk for neurodegenerative disease following mTBI are unknown. This study examined the link between mTBI and brain derived neurotrophic factor (BDNF) genotype, which has previously been shown to regulate processes involved in neurodegeneration including synaptic plasticity and facilitation of neural survival through its expression...
July 28, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28755271/multiclassifier-systems-for-predicting-neurological-outcome-of-patients-with-severe-trauma-and-polytrauma-in-intensive-care-units
#16
Javier González-Robledo, Félix Martín-González, Mercedes Sánchez-Barba, Fernando Sánchez-Hernández, María N Moreno-García
This paper presents an ensemble based classification proposal for predicting neurological outcome of severely traumatized patients. The study comprises both the whole group of patients and a subgroup containing those patients suffering traumatic brain injury (TBI). Data was gathered from patients hospitalized in the Intensive Care Unit (ICU) of the University Hospital in Salamanca. Predictive models were induced from both epidemiologic and clinical variables taken at the emergency room and along the stay in the ICU...
September 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28753439/quo-vadis-tracing-the-fate-of-neural-crest-cells
#17
REVIEW
Luis Zurkirchen, Lukas Sommer
The neural crest is a transient structure in vertebrate embryos that produces migratory cells with an astonishing developmental potential. While neural crest fate maps have originally been established through interspecies transplantation assays, dye labeling, and retroviral infection, more recent methods rely on approaches involving transgenesis and genome editing. These technologies allowed the identification of minor neural crest-derived cell populations in tissues of non-neural crest origin. Furthermore, in vivo multipotency at the single cell level and stage-dependent fate acquisitions were demonstrated using genetic technologies...
July 25, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/28752288/application-of-next-generation-sequencing-technology-to-diagnosis-and-treatment-of-focal-segmental-glomerulosclerosis
#18
REVIEW
Yutaka Harita
A broad range of genetic and non-genetic factors can lead to kidney injury that manifests as focal segmental glomerulosclerosis (FSGS), which can be classified into primary (idiopathic) and secondary forms. Previous genetic approaches to familial or sporadic cases of FSGS or steroid-resistant nephrotic syndrome identified causal mutations in a subset of genes. Recently, next-generation sequencing (NGS) approaches are becoming a part of a standard assessment in medical genetics. Current knowledge of the comprehensive genomic information is changing the way we think about FSGS and draws attention not only to identification of novel causal genes, but also to potential roles for combinations of mutations in multiple genes, mutations with complex inheritance, and susceptibility genes with variable penetrance carrying relatively minor but significant effects...
July 27, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/28752090/dr-buzby-s-toegrips-%C3%A2-application-results-in-minimal-changes-in-kinetic-gait-parameters-in-normal-dogs
#19
James K Roush, Leslie E Moore, Walter C Renberg
Poor traction on slick surfaces is difficult for dogs with neurologic deficits, osteoarthritis, or recovering from injury or surgery. Many dogs respond inappropriately to slick surfaces by decreasing digital pad-floor contact and extending their toenails. A device marketed to increase paw-floor friction in dogs was evaluated. Fifteen normal dogs underwent kinetic gait analysis before and after application of Dr. Buzby's ToeGrips(®). Ground reaction forces, including vertical peak force (VPF) and impulse for each limb, were measured and compared between pre- and post-application values...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28751530/a-10-year-review-of-child-injury-hospitalisations-health-outcomes-and-treatment-costs-in-australia
#20
Rebecca J Mitchell, Kate Curtis, Kim Foster
BACKGROUND: Childhood injury is a leading cause of hospitalisation, yet there has been no comprehensive examination of child injury and survival over time in Australia. To examine the characteristics, temporal trend and survival for children who were hospitalised as a result of injury in Australia. METHOD: A retrospective examination of linked hospitalisation and mortality data for injured children aged 16 years or less during 1 July 2001 to 30 June 2012. Negative binomial regression examined change in injury hospitalisation trends...
July 27, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
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