keyword
https://read.qxmd.com/read/38619048/optimizing-transseptal-puncture-guided-by-three-dimensional-mapping-role-of-unipolar-electrogram-on-needle-tip
#1
JOURNAL ARTICLE
Yifan Chen, Xiaoyan Wu, Mengting Yang, Zhibin Li, Ruya Zhou, Weiqian Lin, Cheng Zheng, Youdong Hu, Jin Li, Yuechun Li, Jiafeng Lin, Mark M Gallagher, Jia Li
BACKGROUND AND AIMS: A three-dimensional electroanatomic mapping system-guided transseptal puncture (3D-TSP), without fluoroscopy or echocardiography, was insufficiently reported. Indications for 3D-TSP remain unclear. This study aimed to establish a precise technique and create a workflow for validating and selecting eligible patients for fluoroless 3D-TSP. METHODS AND RESULTS: We developed a new methodology for 3D-TSP based on the unipolar electrogram derived from transseptal needle tip (UEGM-tip) in 102 cases (the derivation cohort) with intracardiac echocardiography (ICE) from March 2018 to February 2019...
April 15, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/38618892/an-in-depth-study-on-the-magnetic-resonance-imaging-characteristics-of-tendon-rupture-in-sports-injuries-and-its-correlation-with-patients-clinical-symptoms
#2
JOURNAL ARTICLE
Haihua Shi, Lingjuan Jv, Jungang Xu, Xiangyu Qian
Muscle injuries, such as Achilles and quadriceps tendon ruptures, pose a significant challenge in elite sports, accounting for more than 30% of all sports-related injuries. Our primary goal is to investigate the MR imaging characteristics of tendon rupture in sports injuries and their relationship with patients' clinical symptoms. In our retrospective study at Zhejiang University of Traditional Chinese Medicine's Second Affiliated Hospital (Zhejiang Xinhua Hospital), we compared the clinical presentation and MRI results of 106 patients with isolated AT and QT ruptures...
April 12, 2024: European Journal of Translational Myology
https://read.qxmd.com/read/38618683/ankle-muscle-strength-and-gait-function-after-dorsal-closing-wedge-calcaneal-osteotomy-for-haglund-exostosis-related-heel-pain
#3
JOURNAL ARTICLE
Bernd Friesenbichler, Thomas Rutishauer, Pascal Rippstein, Renate List, Samara Monn, Jens Mainzer, Nicola A Maffiuletti
BACKGROUND: Haglund exostosis-related heel pain may be surgically treated with dorsal closing wedge calcaneal osteotomy (DCWCO). Recent reports on this technique show good clinical and self-reported outcomes. However, uncertainty about functional consequences related to ankle muscle strength and gait function due to a shortened Achilles tendon lever arm exists. METHODS: Fifteen patients (15 feet) with Haglund exostosis-related heel pain were surgically treated with DCWCO and evaluated before and 1 year after surgery...
April 15, 2024: Foot & Ankle International
https://read.qxmd.com/read/38618273/road-traffic-injuries-in-south-africa-a-complex-global-health-crisis
#4
JOURNAL ARTICLE
Heike Geduld, Marion Sinclair, Elmin Steyn, Kathryn Chu
1.3 million people die each year as a result of Road traffic crashes. Road Traffic Injuries are a global health crisis with 90% of global deaths affecting LMICs. Sustainable Development Goal 3.6 focuses on reducing road injury and death. The global plan is based on the Safe Systems approach. In South Africa, the burden of crashes on the health system and society is particularly high with a population death rate of 20.7 per 100 000 population. Understanding local context and culture is critical. Rurality, distorted urban planning, higher travel exposure and alcohol usage disproportionately impact racial and ethnic minorities...
2024: Annals of Global Health
https://read.qxmd.com/read/38617372/3d-imaging-reveals-changes-in-the-neurovascular-architecture-of-the-murine-calvarium-with-aging
#5
Allison L Horenberg, Yunke Ren, Alexandra N Rindone, Arvind P Pathak, Warren L Grayson
Calvarial nerves, along with vasculature, influence skull formation during development and following injury, but it remains unclear how calvarial nerves are spatially distributed during postnatal growth and aging. Studying the spatial distribution of nerves in the skull remains challenging due to a lack of methods to image and quantify 3D structures in intact bone. To visualize calvarial 3D neurovascular architecture, we imaged nerves and endothelial cells with lightsheet microscopy. We employed machine-learning-based segmentation to facilitate high-resolution characterization from post-natal day 0 (P0) to Week 80 (80wk)...
April 1, 2024: bioRxiv
https://read.qxmd.com/read/38613833/evaluating-the-impact-of-an-interdisciplinary-integrated-limb-preservation-service-operating-concurrently-with-a-single-specialty-service
#6
JOURNAL ARTICLE
Sebouh Bazikian, Alyssa J Pyun, Hanke Zheng, William Padula, Tanzim Khan, Kenneth Ziegler, Laura Shin, Gregory A Magee, Vincent L Rowe, David G Armstrong
BACKGROUND: This study examined the efficacy of an interdisciplinary limb preservation service (LPS) in improving surgical outcomes for diabetic foot ulcer (DFU) patients compared to traditional care. METHODS: Data from January 1, 2017 to September 30, 2020 were retrospectively reviewed. An interdisciplinary LPS clinic began on August 1, 2018, coexisting with a preexisting single specialty service. Primary outcomes were major/minor amputation rates and ratios and hospital length of stay...
June 2024: Journal of Foot and Ankle Research
https://read.qxmd.com/read/38610680/the-impact-of-injury-on-career-progression-in-elite-youth-football-findings-at-10-years
#7
JOURNAL ARTICLE
Yannic Bangert, Ayham Jaber, Raphael Trefzer, Severin Zietzschmann, Kevin-Arno Koch, Ralph Kern, Jan Spielmann, Tobias Renkawitz, Johannes Weishorn
Background : There is a lack of evidence regarding the impact of time loss, match exposure, and age at injury on career progression in elite football. Therefore, the aim of this study was to identify injury characteristics and their influence on career progression in a German youth academy. Methods : During the 2012/2013 season, a prospective cohort study reported 107 time-loss injuries among 130 young athletes from an elite German soccer academy. Individual career progression was analyzed using 10-year data...
March 26, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38609287/pecarn-prediction-rules-for-ct-imaging-of-children-presenting-to-the-emergency-department-with-blunt-abdominal-or-minor-head-trauma-a-multicentre-prospective-validation-study
#8
JOURNAL ARTICLE
James F Holmes, Kenneth Yen, Irma T Ugalde, Paul Ishimine, Pradip P Chaudhari, Nisa Atigapramoj, Mohamed Badawy, Kevan A McCarten-Gibbs, Donovan Nielsen, Allyson C Sage, Grant Tatro, Jeffrey S Upperman, P David Adelson, Daniel J Tancredi, Nathan Kuppermann
BACKGROUND: The intra-abdominal injury and traumatic brain injury prediction rules derived by the Pediatric Emergency Care Applied Research Network (PECARN) were designed to reduce inappropriate use of CT in children with abdominal and head trauma, respectively. We aimed to validate these prediction rules for children presenting to emergency departments with blunt abdominal or minor head trauma. METHODS: For this prospective validation study, we enrolled children and adolescents younger than 18 years presenting to six emergency departments in Sacramento (CA), Dallas (TX), Houston (TX), San Diego (CA), Los Angeles (CA), and Oakland (CA), USA between Dec 27, 2016, and Sept 1, 2021...
May 2024: Lancet Child & Adolescent Health
https://read.qxmd.com/read/38608812/implementation-of-the-modified-brain-injury-guideline-may-be-feasible-and-cost-effective-even-in-a-non-trauma-hospital
#9
JOURNAL ARTICLE
Katie L Krause, Alisha Brown, Joshua Michael, Mike Mercurio, Sean Wo, Aiyush Bansal, Jordan Becerril, Suheir Khajuria, Evan Coates, Jean-Christophe Andre Leveque
INTRODUCTION: The modified Brain Injury Guideline (mBIG) is a framework to stratify traumatic brain injury (TBI) patients based on clinical and radiographic factors in level 1 and 2 trauma centers. Approximately 75% of all US hospitals do not carry any trauma designation yet may also benefit from these guidelines. This is the first report of applying the mBIG protocol in a community hospital without any trauma designation. METHODS: All adult patients with a TBI in a single center during the years 2020-2022 were retrospectively classified into mBIG categories...
April 10, 2024: World Neurosurgery
https://read.qxmd.com/read/38608809/profile-of-patients-receiving-ct-scans-for-mild-traumatic-brain-injury-in-a-tertiary-care-hospital-in-ethiopia
#10
JOURNAL ARTICLE
Yegeta Wondafrash Habte, Belinda Shao, Hengameh B Pajer, Kevin L Ma, Temesgen Beyene Abicho, Yohannes Feleke, Yacob Alemu Bizuneh, Tsegazeab Laeke, Abenezer Tirsit, Heather S Spader
BACKGROUND: Traumatic brain injury (TBI) is a leading contributor to emergency department (ED) mortalities in Ethiopia. Mild TBI patients comprise half of all TBI patients presenting for care in Ethiopia and have a high potential for recovery. As such, context-specific care-improving strategies may be highly impactful for this group of patients. OBJECTIVE: This study examines the presentation and disposition of mTBI patients who received a computed tomography scan of the head (CTH) upon arrival at the largest teaching hospital in Ethiopia...
April 10, 2024: World Neurosurgery
https://read.qxmd.com/read/38608468/risk-factors-for-clinically-important-traumatic-brain-injury-in-minor-head-injury-in-older-people
#11
JOURNAL ARTICLE
Makoto Uchiyama, Kosuke Mori, Takeru Abe, Shohei Imaki
BACKGROUND AND OBJECTIVES: The incidence of traumatic brain injury (TBI) in older individuals is increasing with an increase in the older population. For older people, the required medical interventions and hospitalization following minor head injury have negative impacts, which have not been reported in literature up till now. We aimed to investigate the risk factors for clinically important traumatic brain injury (ciTBI) in older patients with minor head injury. METHODS: This is a retrospective single-center cohort study...
April 7, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38604235/flexed-position-of-the-wrist-in-the-cast-reliably-prevents-displacement-after-physeal-salter-harris-i-and-ii-distal-radius-fractures
#12
JOURNAL ARTICLE
Rok Kralj, Mario Kurtanjek, Ivan Silvije Gržan, Igor Bumči, Stjepan Višnjić, Rado Žic
BACKGROUND: Salter-Harris I and II fractures of the distal radius are common injuries. In our facility, immobilisation is performed in a way that counteracts angulation forces. The aim of our study was to determine whether there are significant differences between patients with and patients without a loss of reduction treated with this method and to determine what degree of flexion reliably prevents secondary displacement. PATIENTS AND METHODS: We conducted a retrospective study of 112 patients (mean age: 12 years) who had sustained a Salter-Harris type I or II fracture of the distal radius and were treated with reduction...
April 11, 2024: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://read.qxmd.com/read/38598615/a-mouse-model-of-chronic-primary-pain-that-integrates-clinically-relevant-genetic-vulnerability-stress-and-minor-injury
#13
JOURNAL ARTICLE
Yaomin Wang, Shin Hyung Kim, Marguerita E Klein, Jiegen Chen, Elizabeth Gu, Shad Smith, Andrey Bortsov, Gary D Slade, Xin Zhang, Andrea G Nackley
Chronic primary pain conditions (CPPCs) affect over 100 million Americans, predominantly women. They remain ineffectively treated, in large part because of a lack of valid animal models with translational relevance. Here, we characterized a CPPC mouse model that integrated clinically relevant genetic (catechol-O-methyltransferase; COMT knockdown) and environmental (stress and injury) factors. Compared with wild-type mice, Comt +/- mice undergoing repeated swim stress and molar extraction surgery intervention exhibited pronounced multisite body pain and depressive-like behavior lasting >3 months...
April 10, 2024: Science Translational Medicine
https://read.qxmd.com/read/38598281/the-use-of-medical-services-for-low-acuity-emergency-cases-in-germany-protocol-for-a-multicenter-observational-pilot-study
#14
JOURNAL ARTICLE
Lara Maria Nau, Gunter Laux, Attila Altiner, Joachim Szecsenyi, Rüdiger Leutgeb
BACKGROUND: The increasing number of requests for help for acutely ill patients and their management is a major problem in the health systems of many countries, but especially in Germany. Rescue coordination centers and ambulances in Germany are increasingly overloaded. As a result, rides as a part of rescue operations have been increasing in length for years, yet a relevant proportion of these operations represent low-acuity calls (LACs). The basic objective of this pilot study is the quantitative analysis of the potential misuse of requests to the rescue control center...
April 10, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38597144/treatment-with-rnase-alleviates-brain-injury-but-not-neuroinflammation-in-neonatal-hypoxia-ischemia
#15
JOURNAL ARTICLE
Rozita H Anderberg, E Axel Andersson, Valentina Bucher, Klaus T Preissner, Carina Mallard, C Joakim Ek
There is a need for new treatments to reduce brain injuries derived from neonatal hypoxia/ischemia. The only viable option used in the clinic today in infants born at term is therapeutic hypothermia, which has a limited efficacy. Treatments with exogenous RNase have shown great promise in a range of different adult animal models including stroke, ischemia/reperfusion injury, or experimental heart transplantation, often by conferring vascular protective and anti-inflammatory effects. However, any neuroprotective function of RNase treatment in the neonate remains unknown...
April 2024: Journal of Neuroscience Research
https://read.qxmd.com/read/38596829/employing-machine-learning-to-enhance-fracture-recovery-insights-through-gait-analysis
#16
JOURNAL ARTICLE
Mostafa Rezapour, Rachel B Seymour, Stephen H Sims, Madhav A Karunakar, Nahir Habet, Metin Nafi Gurcan
This study aimed to explore the potential of gait analysis coupled with supervised machine learning models as a predictive tool for assessing post-injury complications such as infection, malunion, or hardware irritation among individuals with lower extremity fractures. We prospectively identified participants with lower extremity fractures at a tertiary academic center. These participants underwent gait analysis with a chest-mounted inertial measurement unit device. Using customized software, the raw gait data were preprocessed, emphasizing 12 essential gait variables...
April 10, 2024: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://read.qxmd.com/read/38596574/medial-femoral-condyle-free-flap-a-systematic-review-and-proportional-meta-analysis-of-applications-and-surgical-outcomes
#17
JOURNAL ARTICLE
Matteo Scampa, Vladimir Mégevand, Jérôme Martineau, Dirk J Schaefer, Daniel F Kalbermatten, Carlo M Oranges
BACKGROUND: Recalcitrant bone nonunion and osseous defect treatment is challenging and often requires vascularized bone transfer. The medial femoral condyle flap has become an increasingly popular option for reconstruction. The study aims at reviewing its different applications and synthesizing its surgical outcomes. METHOD: A systematic review including all studies assessing surgical outcomes of free medial femoral condyle flap for bone reconstruction in adults was conducted on January 31, 2023...
April 2024: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/38595266/plasma-proteomics-profile-based-comparison-of-torso-versus-brain-injury-a-prospective-cohort-study
#18
JOURNAL ARTICLE
Jotaro Tachino, Yuki Togami, Hisatake Matsumoto, Tsunehiro Matsubara, Shigeto Seno, Hiroshi Ogura, Jun Oda
INTRODUCTION: Trauma-related deaths and post-traumatic sequelae are a global health concern, necessitating a deeper understanding of the pathophysiology to advance trauma therapy. Proteomics offers insights into identifying and analyzing plasma proteins associated with trauma and inflammatory conditions; however, current proteomic methods have limitations in accurately measuring low-abundance plasma proteins. This study compared plasma proteomics profiles of patients from different acute trauma subgroups to identify new therapeutic targets and devise better strategies for personalized medicine...
April 10, 2024: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/38592225/lower-extremity-trauma-a-multidimensional-reconstructive-approach-with-hyperbaric-oxygen-therapy
#19
JOURNAL ARTICLE
Caterina Marra, Paola Pentangelo, Luigi Losco, Alessandra Ceccaroni, Alfonso Barbato, Carmine Alfano
Background : Distal lower extremity reconstruction is challenging. This study aims to propose a protocol for the treatment of traumatic soft tissue defects. The key concept is to combine the surgical armamentarium of the reconstructive surgeon with the advantages provided by hyperbaric oxygen therapy. Methods : This retrospective study analyzed data of 57 patients affected with unilateral or bilateral lower extremity trauma distal to the knee and involving soft tissues with no indication of immediate reconstruction between 2010 and 2021...
February 29, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38590922/successful-treatment-of-atypical-femoral-fracture-with-autogenous-bone-grafting-in-a-patient-on-denosumab-for-bone-metastasis-from-breast-cancer-a-case-report
#20
Taiki Yasukawa, Sang Yang Lee, Hiro Hasegawa, Koki Tsuchiya, Toshiyuki Shirahata, Makoto Yoshimura, Yoshifumi Kudo
Atypical femoral fractures (AFFs) occur with minor trauma and are believed to be a potential complication of the prolonged use of antiresorptive agents, such as bisphosphonate and denosumab, for the treatment of bone metastasis. In comparison with typical femoral fractures, AFFs have a higher incidence of complications, including implant failure and delayed union or nonunion. This report describes the case of a 42-year-old woman who developed denosumab-associated AFF after denosumab therapy for bone metastasis from breast cancer...
June 2024: Trauma Case Reports
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