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https://www.readbyqxmd.com/read/29143594/the-gene-smart-study-method-study-design-and-preliminary-findings
#1
REVIEW
Xu Yan, Nir Eynon, Ioannis D Papadimitriou, Jujiao Kuang, Fiona Munson, Oren Tirosh, Lannie O'Keefe, Lyn R Griffiths, Kevin J Ashton, Nuala Byrne, Yannis P Pitsiladis, David J Bishop
The gene SMART (genes and the Skeletal Muscle Adaptive Response to Training) Study aims to identify genetic variants that predict the response to both a single session of High-Intensity Interval Exercise (HIIE) and to four weeks of High-Intensity Interval Training (HIIT). While the training and testing centre is located at Victoria University, Melbourne, three other centres have been launched at Bond University, Queensland University of Technology, Australia, and the University of Brighton, UK. Currently 39 participants have already completed the study and the overall aim is to recruit 200 moderately-trained, healthy Caucasians participants (all males 18-45 y, BMI < 30)...
November 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29112625/ischemic-preconditioning-improves-time-trial-performance-at-moderate-altitude
#2
Pénélope Paradis-Deschênes, Denis R Joanisse, François Billaut
PURPOSE: Endurance athletes often compete and train at altitude where exercise capacity is reduced. Investigating acclimation strategies is therefore critical. Ischemic preconditioning (IPC) can improve endurance performance at sea level through improved O2 delivery and utilization, which could also prove beneficial at altitude. However, data are scarce and there is no study at altitudes commonly visited by endurance athletes. METHODS: In a randomized, crossover study, we investigated performance and physiological responses in thirteen male endurance cyclists during four 5-km cycling time trials (TT), preceded by either IPC (3x5-minutes ischemia/5-minutes reperfusion cycles at 220 mmHg) or SHAM (20 mmHg) administered to both thighs, at simulated low (FIO2 0...
November 6, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29108901/keto-adaptation-enhances-exercise-performance-and-body-composition-responses-to-training-in-endurance-athletes
#3
Fionn T McSwiney, Bruce Wardrop, Parker N Hyde, Richard A Lafountain, Jeff S Volek, Lorna Doyle
BACKGROUND: Low-carbohydrate diets have recently grown in popularity among endurance athletes, yet little is known about the long-term (>4 wk) performance implications of consuming a low-carbohydrate high fat ketogenic diet (LCKD) in well-trained athletes. METHODS: Twenty male endurance-trained athletes (age 33 ± 11y, body mass 80 ± 11kg; BMI 24.7 ± 3.1 kg/m(2)) who habitually consumed a carbohydrate-based diet, self-selected into a high-carbohydrate (HC) group (n = 11, %carbohydrate:protein:fat = 65:14:20), or a LCKD group (n = 9, 6:17:77)...
November 3, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29099231/effects-of-high-intensity-intermittent-training-on-vascular-function-in-obese-preadolescent-boys
#4
Napasakorn Chuensiri, Daroonwan Suksom, Hirofumi Tanaka
BACKGROUND: High-intensity intermittent training (HIIT) may serve as an effective alternative to traditional endurance training, since HIIT has been shown to induce greater improvements in aerobic fitness and health-related markers in adult populations. Our objective was to determine whether HIIT and supramaximal high-intensity intermittent training (supra-HIIT) would improve vascular structure and function in obese preadolescent boys. METHODS: Before the baseline testing, 48 obese preadolescent boys, aged 8-12 years, were randomly assigned into control (CON; n = 16), HIIT (8 × 2 minutes at 90% peak power output, n = 16), and supra-HIIT (8 × 20 seconds at 170% peak power output, n = 16) groups...
November 3, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/29097231/poor-anaerobic-power-capability-and-static-balance-predicted-prospective-musculoskeletal-injuries-among-soldiers-of-the-101st-airborne-air-assault-division
#5
Takashi Nagai, Mita Lovalekar, Meleesa F Wohleber, Katherine A Perlsweig, Michael D Wirt, Kim Beals
Musculoskeletal injuries have negatively impacted tactical readiness. The identification of prospective and modifiable risk factors of preventable musculoskeletal injuries can guide specific injury prevention strategies for Soldiers and health care providers. OBJECTIVES: To analyze physiological and neuromuscular characteristics as predictors of preventable musculoskeletal injuries. DESIGN: Prospective-cohort study. METHODS: A total of 491 Soldiers were enrolled and participated in the baseline laboratory testing, including body composition, aerobic capacity, anaerobic power/capacity, muscular strength, flexibility, static balance, and landing biomechanics...
October 24, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29076961/six-sessions-of-sprint-interval-training-improves-running-performance-in-trained-athletes
#6
Jerome Koral, Dustin J Oranchuk, Roberto Herrera, Guillaume Y Millet
Sprint interval training (SIT) is gaining popularity with endurance athletes. Various studies have shown that SIT allows similar or greater endurance, strength, and power performance improvements than traditional endurance training, but demands less time and volume. One of the main limitations in SIT research is that most studies were performed in a laboratory using expensive treadmills or ergometers. The aim of this study was to assess the performance effects of a novel short term and highly accessible training protocol based on maximal shuttle runs in the field (SIT-F)...
October 20, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29068603/differences-in-echocardiography-blood-pressure-stroke-volume-maximal-power-and-profile-of-genes-related-to-cardiac-hypertrophy-in-elite-road-cyclists
#7
Grażyna Janikowska, Aleksandra Żebrowska, Aleksandra Kochańska-Dziurowicz, Urszula Mazurek
BACKGROUND: Regular and moderate exercise is beneficial for improving the efficiency of the heart, but high-intensity physical activity may result in cardiac changes. OBJECTIVES: This study focuses on the identification of the differences in echocardiography and blood variables before exercise, as well as the genes associated with cardiac hypertrophy at rest and in response to graded exercise test. MATERIAL AND METHODS: The study group was made up of 28 road cyclists...
September 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29040219/effect-of-2-years-of-endurance-and-high-impact-training-on-preventing-osteoporosis-in-postmenopausal-women-randomized-clinical-trial
#8
Carmen García-Gomáriz, José M Blasco, Cecili Macián-Romero, Elías Guillem-Hernández, Celedonia Igual-Camacho
OBJECTIVE: The aim of the study was to analyze the effects of endurance and high-impact training oriented toward preventing osteoporosis in postmenopausal women with calcium and vitamin D supplementation. METHODS: This study was a randomized clinical trial. Thirty-six postmenopausal women were randomized to the control and experimental groups. Thirty-four women completed the 2-year interventions. The control group training involved walking at an intense pace. The experimental group conducted high-impact training specifically oriented to prevent osteoporosis...
October 16, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28968288/specific-physical-training-in-elite-male-team-handball
#9
Herbert Wagner, Manuel Gierlinger, Nermin Adzamija, Samuel Ajayi, David W Bacharach, Serge P von Duvillard
Wagner, H, Gierlinger, M, Adzamija, N, Ajayi, S, Bacharach, DW, and von Duvillard, SP. Specific physical training in elite male team handball. J Strength Cond Res 31(11): 3083-3093, 2017-Specific physical training in elite team handball is essential for optimal player's performance; however, scientific knowledge is generally based on temporary training studies with subelite athletes. Therefore, the aim of the study was to analyze the effects of specific physical training in an elite male handball team over the entire season...
November 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28964826/randomized-four-arm-dose-response-clinical-trial-to-optimize-resistance-exercise-training-for-older-adults-with-age-related-muscle-atrophy
#10
Michael J Stec, Anna Thalacker-Mercer, David L Mayhew, Neil A Kelly, S Craig Tuggle, Edward K Merritt, Cynthia J Brown, Samuel T Windham, Louis J Dell'Italia, C Scott Bickel, Brandon M Roberts, Kristina M Vaughn, Irina Isakova-Donahue, Gina M Many, Marcas M Bamman
PURPOSE: The myriad consequences of age-related muscle atrophy include reduced muscular strength, power, and mobility; increased risk of falls, disability, and metabolic disease; and compromised immune function. At its root, aging muscle atrophy results from a loss of myofibers and atrophy of the remaining type II myofibers. The purpose of this trial (NCT02442479) was to titrate the dose of resistance training (RT) in older adults in an effort to maximize muscle regrowth and gains in muscle function...
December 1, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28960010/the-effect-of-salt-concentration-on-swelling-power-rheological-properties-and-saltiness-perception-of-waxy-normal-and-high-amylose-maize-starch
#11
Xudong Zhang, Dongwei Guo, Jiquan Xue, Stavros Yanniotis, Ioanna Mandala
The effect of salt concentration on swelling power, rheological properties and saltiness perception of waxy, normal and high amylose maize starch was investigated. The swelling power decreased with increasing salt concentration from 0% to 2.0% among all starch samples. Waxy starch showed the highest swelling power at different salt levels, while high amylose starch showed the least swelling power. The salt addition increased the gelatinization temperature of waxy starch and normal starch from 71.3 °C to 77...
September 29, 2017: Food & Function
https://www.readbyqxmd.com/read/28936625/the-reproducibility-of-4-km-time-trial-tt-performance-following-individualised-sodium-bicarbonate-supplementation-a-randomised-controlled-trial-in-trained-cyclists
#12
Lewis Anthony Gough, Sanjoy Kumar Deb, Andy Sparks, Lars Robert McNaughton
BACKGROUND: Individual time to peak blood bicarbonate (HCO3(-)) has demonstrated good to excellent reproducibility following ingestion of both 0.2 g kg(-1) body mass (BM) and 0.3 g kg(-1) BM sodium bicarbonate (NaHCO3), but the consistency of the time trial (TT) performance response using such an individualised NaHCO3 ingestion strategy remains unknown. This study therefore evaluated the reproducibility of 4-km TT performance following NaHCO3 ingestion individualised to time to peak blood bicarbonate...
September 21, 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28910757/learning-building-extraction-in-aerial-scenes-with-convolutional-networks
#13
Jiangye Yuan
Extracting buildings from aerial scene images is an important task with many applications. However, this task is highly difficult to automate due to extremely large variations of building appearances, and still heavily relies on manual work. To attack this problem, we design a deep convolutional network with a simple structure that integrates activation from multiple layers for pixel-wise prediction, and introduce the signed distance function of building boundaries as the output representation, which has an enhanced representation power...
September 11, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28902115/repeated-high-intensity-cycling-performance-is-unaffected-by-timing-of-carbohydrate-ingestion
#14
Ren-Jay Shei, Hunter L Paris, Christopher P Beck, Robert F Chapman, Timothy D Mickleborough
To determine whether carbohydrate feeding taken immediately before, early, or late in a series of high-intensity cycling exercises affected cycling performance 16 trained, male cyclists (> 6hr post-prandial) performed three, 4-km cycling time trials (TT1, TT2, TT3) separated by 15 min of active recovery on four separate occasions. Carbohydrate feeding (80g) was given either before TT1 (PRE1), before TT2 (PRE2), before TT3 (PRE3), or not at all (control, CTL). Treatment order was randomized. Sweet-placebo was given prior to the other time trials...
September 6, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28895467/kinetic-and-kinematic-patterns-during-high-intensity-clean-movement-searching-for-optimal-load
#15
Achraf Ammar, Bryan L Riemann, Liwa Masmoudi, Marcel Blaumann, Osama Abdelkarim, Anita Hökelmann
The aim of the present study was to investigate loading effects on kinematic and kinetic variables among elite-weightlifters in order to identify an optimal training load to maximize power production for clean-movement. Nine elite-weightlifter (age: 24 ± 4years, body-mass: 77 ± 6.5kg, height: 176 ± 6.1cm and 1RM clean: 170 ± 5kg) performed 2 separate repetitions of the clean using 85, 90, 95% and 100%, in a randomized order, while standing on a force platform and being recorded using 3D-capture-system. Differences in kinematics (barbell displacement, velocity and acceleration) and kinetics (power, vertical ground reaction force (vGRF), rate of force development (RFD), and work) across the loads were statistically assessed...
September 12, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28892463/effect-of-different-velocity-loss-thresholds-during-a-power-oriented-resistance-training-program-on-the-mechanical-capacities-of-lower-body-muscles
#16
Alejandro Pérez-Castilla, Amador García-Ramos, Paulino Padial, Antonio J Morales-Artacho, Belén Feriche
This study compared the effects of two velocity loss thresholds during a power-oriented resistance training program on the mechanical capacities of lower-body muscles. Twenty men were counterbalanced in two groups (VL10 and VL20) based on their maximum power capacity. Both groups used the same exercises, relative intensity and repetition volume, only differing in the velocity loss threshold of each set (VL10: 10% vs. VL20: 20%). Pre- and post-training assessments included an incremental loading test and a 15-m linear sprint to assess the force- and load-velocity relationships and athletic performance variables, respectively...
September 11, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28881965/deep-learning-based-subdivision-approach-for-large-scale-macromolecules-structure-recovery-from-electron-cryo-tomograms
#17
Min Xu, Xiaoqi Chai, Hariank Muthakana, Xiaodan Liang, Ge Yang, Tzviya Zeev-Ben-Mordehai, Eric P Xing
Motivation: Cellular Electron CryoTomography (CECT) enables 3D visualization of cellular organization at near-native state and in sub-molecular resolution, making it a powerful tool for analyzing structures of macromolecular complexes and their spatial organizations inside single cells. However, high degree of structural complexity together with practical imaging limitations makes the systematic de novo discovery of structures within cells challenging. It would likely require averaging and classifying millions of subtomograms potentially containing hundreds of highly heterogeneous structural classes...
July 15, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28872380/optimizing-heat-acclimation-for-endurance-athletes-high-vs-low-intensity-training
#18
Cyril Schmit, Rob Duffield, Christophe Hausswirth, Jeanick Brisswalter, Yann Le Meur
PURPOSE: We sought to determine the effect of high- vs. low-intensity training in the heat and ensuing taper period in the heat on endurance performance. METHODS: Nineteen well-trained triathletes undertook 5 days of normal training and a 1-week taper, including either low- (HA-L, n=10) or high-intensity (HA-H, n=9) training sessions in the heat (30°C, 50% of relative humidity). A control group (n=10) reproduced their usual training in thermoneutral conditions...
September 5, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28869746/physiological-intensity-profile-exercise-load-and-performance-predictors-of-a-65-km-mountain-ultra-marathon
#19
Alessandro Fornasiero, Aldo Savoldelli, Damiano Fruet, Gennaro Boccia, Barbara Pellegrini, Federico Schena
The aims of the study were to describe the physiological profile of a 65-km (4000-m cumulative elevation gain) running mountain ultra-marathon (MUM) and to identify predictors of MUM performance. Twenty-three amateur trail-runners performed anthropometric evaluations and an uphill graded exercise test (GXT) for VO2max, ventilatory thresholds (VTs), power outputs (PMax, PVTs) and heart rate response (HRmax, HR@VTs). Heart rate (HR) was monitored during the race and intensity was expressed as: Zone I (<VT1), Zone II (VT1-VT2), Zone III (>VT2) for exercise load calculation (training impulse, TRIMP)...
September 4, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28864705/a-protocol-for-a-randomised-controlled-trial-of-the-bone-response-to-impact-loading-or-resistance-training-in-young-women-with-lower-than-average-bone-mass-the-optima-ex-trial
#20
Conor Lambert, Belinda R Beck, Amy T Harding, Steven L Watson, Benjamin K Weeks
INTRODUCTION: The aim of the Osteoporosis Prevention Through Impact and Muscle-loading Approaches to Exercise trial is to compare the bone response to two known osteogenic stimuli - impact loading exercise and resistance training. Specifically, we will examine the effect of a 10-month, twice-weekly, high-intensity impact loading exercise intervention and a 10-month, twice-weekly, high-intensity resistance training intervention on bone mass and strength at clinically important skeletal sites...
September 1, 2017: BMJ Open
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