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Pediatric language delay

Matt S Hicks, Reginald S Sauve, Charlene M T Robertson, Ari R Joffe, Gwen Alton, Dianne Creighton, David B Ross, Ivan M Rebeyka
BACKGROUND: Developmental and language outcomes at 2 years of age of children who had arterial switch operation (ASO) for transposition of the great arteries 2004-2010 are described. METHODS: In this prospective cohort study, 91/98 (93 %) children who underwent ASO were assessed at 2 years of age with the Bayley Scales of Infant & Toddler Development-3rd Edition. Outcomes were compared by patient and perioperative variables using bivariate and multivariate regression analyses to identify predictors of language delay...
2016: SpringerPlus
Gerasimos Kolaitis, Christian G Bouwkamp, Alexia Papakonstantinou, Ioanna Otheiti, Maria Belivanaki, Styliani Haritaki, Terpsihori Korpa, Zinovia Albani, Elena Terzioglou, Polyxeni Apostola, Aggeliki Skamnaki, Athena Xaidara, Konstantina Kosma, Sophia Kitsiou-Tzeli, Maria Tzetis
BACKGROUND: This is a case with multiple chromosomal aberrations which are likely etiological for the observed psychiatric phenotype consisting of attention deficit hyperactivity and conduct disorders. CASE PRESENTATION: We report on an 11 year-old boy, admitted to the pediatric hospital for behavioral difficulties and a delayed neurodevelopmental trajectory. A cytogenetic analysis and high-resolution microarray comparative genomic hybridization (CGH) analysis was performed...
2016: Child and Adolescent Psychiatry and Mental Health
Hend Soliman, Aisha Fawzy Abdel Hady, Asmaa Abdel Hamid, Heba Mahmoud
OBJECTIVE: The aim of this work was to evaluate receptive and expressive language skills in children with congenital hypothyroidism receiving early hormonal replacement treatment before the age of 3 months and to identify any subtle areas of weaknesses in their language development to check the necessity for future language intervention. PATIENTS AND METHODS: The study was conducted on 30 hypothyroid children receiving hormonal replacement. They were subdivided into group I (5-8 years 11 months; 12 cases) and group II (9-12 years 11 months; 18 cases)...
September 2, 2016: Folia Phoniatrica et Logopaedica
James P Guevara, Brooke Rothman, Elizabeth Brooks, Marsha Gerdes, Fayetta McMillon-Jones, Katherine Yun
INTRODUCTION: Few eligible children participate in early intervention (EI) programs. The objective of this study was to determine feasibility and outcomes of a novel patient navigation program on EI referrals among a diverse group of at-risk children. METHODS: During a 6-month period, a patient navigator was assigned to an urban pediatric clinic to engage families, provide education on early child development and EI, and assist families with completing multidisciplinary evaluations...
September 2016: Families, Systems & Health: the Journal of Collaborative Family Healthcare
Eduardo R Zamora, Sapna Kaul, Anne C Kirchhoff, Vannina Gwilliam, Ornella A Jimenez, Deborah K Morreall, Roberto E Montenegro, Anita Y Kinney, Mark N Fluchel
BACKGROUND: An increasing proportion of pediatric cancer patients in the United States are Latino and many have Spanish-speaking immigrant parents with limited English proficiency (LEP). Little is known about how language or undocumented immigration status impacts their care experience. PROCEDURE: A cross-sectional survey was administered to English (N = 310) and Spanish-speaking LEP (N = 56) caregivers of pediatric cancer patients. To assess differences in healthcare experiences between the language groups, t-tests and chi-square statistics were used...
July 21, 2016: Pediatric Blood & Cancer
Irina Castellanos, David B Pisoni, William G Kronenberger, Jessica Beer
PURPOSE: The objective of the present article was to document the extent to which early expressive language skills (measured using the MacArthur-Bates Communicative Development Inventories [CDI; Fenson et al., 2006]) predict long-term neurocognitive outcomes in a sample of early-implanted prelingually deaf cochlear implant (CI) users. METHOD: The CDI was used to index the early expressive language skills of 32 pediatric CI users after an average of 1.03 years (SD = 0...
August 1, 2016: American Journal of Speech-language Pathology
Yu-Pei Tsai, Li-Chen Tung, Ya-Chen Lee, Yu-Lin Wang, Yun-Shan Yen, Kuan-Lin Chen
OBJECTIVE: The objective of this study was to examine the responsiveness of the Comprehensive Developmental Inventory for Infants and Toddlers (CDIIT) in children with developmental disabilities (DD). METHODS: The responsiveness of a measure is its ability to detect change over time, and it is fundamental to an outcome measure for detecting changes over time. We compared the responsiveness of four types of scores (ie, raw scores, developmental ages [DAs], percentile ranks [PRs], and developmental quotients [DQs]) in the five subtests of the CDIIT...
2016: Neuropsychiatric Disease and Treatment
Doris P Yimgang, Rebecca A Albury, Mary L Leppert
Parental concerns are useful tools to help pediatric care providers identify the presence of developmental and behavioral problems. This study sought to learn whether specific parental concerns helped predict diagnoses in a tertiary developmental clinic. Parents of preschoolers who attended a preschool developmental clinic (n = 101) were surveyed about behavioral and developmental concerns and their concerns about possible diagnoses. Clinical diagnoses were subsequently obtained on all children and compared with parents' primary concerns...
May 19, 2016: Clinical Pediatrics
David N Levin, Jillian Taras, Katherine Taylor
BACKGROUND: Intraoperative transesophageal echocardiography (ITEE) for pediatric cardiac surgery has been described as clinically efficacious and cost-effective. There are a small number of publications supporting these claims. AIMS: The objectives were to assess the quality of the research, the variability of results across studies and, if possible, to make a consensus statement based on the results. METHODS: In March 2015, a systematic search of MEDLINE and MEDLINE In-Process, EMBASE, and the National Health Service Economic Evaluation Database was performed...
July 2016: Paediatric Anaesthesia
Ylva Fredriksson Kaul, Kerstin Rosander, Claes von Hofsten, Katarina Strand Brodd, Gerd Holmström, Alexander Kaul, Birgitta Böhm, Lena Hellström-Westas
BACKGROUND: Typically developing infants track moving objects with eye and head movements in a smooth and predictive way at 4 mo of age, but this ability is delayed in very preterm infants. We hypothesized that visual tracking ability in very preterm infants predicts later neurodevelopment. METHOD: In 67 very preterm infants (gestational age<32 wk), eye and head movements were assessed at 4 mo corrected age while the infant tracked a moving object. Gaze gain, smooth pursuit, head movements, and timing of gaze relative the object were analyzed off line...
July 2016: Pediatric Research
Kerri Neville, Warren Lo
BACKGROUND: There are frequent delays in the diagnosis of acute pediatric ischemic stroke. A screening tool that could increase the suspicion of acute ischemic stroke could aid early recognition and might improve initial care. An earlier study reported that children with acute ischemic stroke have signs that can be recognized with two adult stroke scales. We tested the hypothesis that an adult stroke scale could distinguish children with acute ischemic stroke from children with acute focal neurological deficits not due to stroke...
May 2016: Pediatric Neurology
Sara B Johnson, Jenna L Riis, Kimberly G Noble
In the United States, >40% of children are either poor or near-poor. As a group, children in poverty are more likely to experience worse health and more developmental delay, lower achievement, and more behavioral and emotional problems than their more advantaged peers; however, there is broad variability in outcomes among children exposed to similar conditions. Building on a robust literature from animal models showing that environmental deprivation or enrichment shapes the brain, there has been increasing interest in understanding how the experience of poverty may shape the brain in humans...
April 2016: Pediatrics
Arwa Kurabi, Kwang Pak, Allen F Ryan, Stephen I Wasserman
Otitis media (OM) is a common disease in young children, accounting for more office visits and surgeries than any other pediatric condition. It is associated with an estimated cost of five billion dollars annually in the USA. Moreover, chronic and recurrent middle ear (ME) disease leads to hearing loss during critical periods of language acquisition and learning leading to delays in reaching developmental milestones and risking permanent damage to the ME and inner ear in severe cases. Therefore, research to understand the disease pathogenesis and identify new therapeutics is important...
January 2016: Current Allergy and Asthma Reports
Brenda G Clark, Bryan V Acton, Gwen Y Alton, Ari R Joffe, Irina A Dinu, Charlene M T Robertson
BACKGROUND: Strong recommendations have been made for the periodic developmental surveillance, screening, and evaluation of children with CHD. This supports similar calls for all at-risk children in order to provide timely, structured early developmental intervention that may improve outcomes. The aim of this study was to determine the accuracy of screening for language delay after life-saving therapies using the parent-completed vocabulary screen of the language Development Survey, by comparing screening with the individually administered language scores of the Bayley Scales of Infant and Toddler Development, Third edition...
October 2016: Cardiology in the Young
M Florencia Ricci, Gwen Y Alton, David B Ross, Bryan J Dicken, Diane M Moddemann, Charlene M T Robertson
OBJECTIVE: To compare the proportion of developmental delay in early complex cardiac surgery (CCS) survivors with and without gastrostomy tube feeding (GTF). To explore acute care predictors of GTF that might help improve care in CCS survivors. STUDY GROUP: This comparison study of 2 groups within an inception cohort included 334 CCS survivors after cardiopulmonary bypass at ≤6 weeks of age (2005-2012) who did not require extracorporeal membrane oxygenation or heart transplantation...
February 2016: Journal of Pediatrics
Lobna Mansour, Ezzat El Sobky, Solaf M Mohamed, Huda Marzouk, Lamia A Tarek
BACKGROUND: Rett syndrome (RTT) is an X-linked dominant neurodegenerative disorder with various MECP2 mutations. RTT is one of the most common causes of severe intellectual and complex disability in girls. Therefore, the aims of the study were as follows: to highlight the clinical manifestations of RTT; to present the genotype-phenotype relationship; and to assess the possible relation between severity score, clinical manifestations, and MECP2 gene mutations. PATIENTS AND METHODS: The present cross-sectional study included 15 girls with typical RTT, diagnosed according to the international criteria of RTT...
September 2015: Journal of the Egyptian Public Health Association
Annette Uwineza, Janvier Hitayezu, Mauricette Jamar, Jean-Hubert Caberg, Seraphine Murorunkwere, Ndinkabandi Janvier, Vincent Bours, Leon Mutesa
Global developmental delay (GDD) is defined as a significant delay in two or more developmental domains: gross or fine motor, speech/language, cognitive, social/personal and activities of daily living. Many of these children will go on to be diagnosed with intellectual disability (ID), which is most commonly defined as having an IQ <75 in addition to impairment in adaptive functioning. Cytogenetic studies have been performed in 664 Rwandan pediatric patients presenting GDD/ID and/or multiple congenital abnormalities (MCA)...
February 2016: Journal of Tropical Pediatrics
Kayla M Jasper, Aria Jamshidi, Brian K Reilly
PURPOSE OF REVIEW: Sensorineural hearing loss (SNHL) is the most common sensory birth defect. The purpose of this article is to review the advances in next-generation sequencing (NGS) and molecular diagnosis of hereditary hearing loss. RECENT FINDINGS: Early diagnosis and detection of SNHL is critical for the development of appropriate speech and language, as neuroplasticity peaks in the first few years of life. There has been increased accuracy of NGS genetic testing, which has helped created a paradigm shift in the diagnosis of hearing loss...
December 2015: Current Opinion in Otolaryngology & Head and Neck Surgery
Katie Geelan-Hansen, Samantha Anne
Noonan syndrome is an autosomal dominant disorder with associated anomalies that include short stature, congenital heart defects, developmental delay, and characteristic facial features among other abnormalities. Articulation deficiency and language delay are often present and require speech therapy. Otitis media and hearing loss have been reported to be common in these patients. We performed a retrospective chart review of pediatric patients who were diagnosed with Noonan syndrome at our tertiary care center from January 1979 through December 2009...
September 2015: Ear, Nose, & Throat Journal
Laura A Janzen, Dana David, Darlene Walker, Johann Hitzler, Sue Zupanec, Heather Jones, Brenda J Spiegler
BACKGROUND: Not all children with acute lymphoblastic leukemia (ALL) were developing in a typical manner prior to diagnosis. Pre-existing developmental vulnerabilities (DV) may be related to long-term neuropsychological sequelae following ALL treatment, yet little is known about the prevalence or nature of prior DV in this population. PROCEDURE: Children with newly diagnosed ALL aged 2-18 years (n = 115) were screened for DV by asking parents about the child's prior developmental history and with the Developmental Profile-3 (DP-3)...
December 2015: Pediatric Blood & Cancer
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