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https://www.readbyqxmd.com/read/28088088/prevalence-of-new-psychoactive-substances-in-northeast-asia-from-2007-to-2015
#1
Junhui Lee, Songhee Yang, Yujin Kang, Eunyoung Han, Ling-Yi Feng, Jih-Heng Li, Heesun Chung
The proliferation of new psychoactive substances (NPS) has been a global trend in drug abuse and its regulation has been a worldwide concern. There is no doubt that it is necessary to share information related to these emerging substances between countries and continents for the effective regulation of NPS. With efforts for the efficient regulation of NPS, many studies and information have been published for the prevalence of NPS in the United States and other countries in Europe and Oceania. However, there is lack of information available for the prevalence of NPS in Asian and African countries...
October 20, 2016: Forensic Science International
https://www.readbyqxmd.com/read/28086974/ovarian-cancer-density-equalizing-mapping-of-the-global-research-architecture
#2
Dörthe Brüggmann, Katharina Pulch, Doris Klingelhöfer, Celeste Leigh Pearce, David A Groneberg
BACKGROUND: Despite its impact on female health worldwide, no efforts have been made to depict the global architecture of ovarian cancer research and to understand the trends in the related literature. Hence, it was the objective of this study to assess the global scientific performance chronologically, geographically and in regards to economic benchmarks using bibliometric tools and density equalizing map projections. METHODS: The NewQIS platform was employed to identify all ovarian cancer related articles published in the Web of Science since 1900...
January 13, 2017: International Journal of Health Geographics
https://www.readbyqxmd.com/read/28081442/mapping-and-role-of-the-cd8-t-cell-response-during-primary-zika-virus-infection-in-mice
#3
Annie Elong Ngono, Edward A Vizcarra, William W Tang, Nicholas Sheets, Yunichel Joo, Kenneth Kim, Matthew J Gorman, Michael S Diamond, Sujan Shresta
CD8(+) T cells may play a dual role in protection against and pathogenesis of flaviviruses, including Zika virus (ZIKV). We evaluated the CD8(+) T cell response in ZIKV-infected LysMCre(+)IFNAR(fl/fl) C57BL/6 (H-2(b)) mice lacking the type I interferon receptor in a subset of myeloid cells. In total, 26 and 15 CD8(+) T cell-reactive peptides for ZIKV African (MR766) and Asian (FSS13025) lineage strains, respectively, were identified and validated. CD8(+) T cells from infected mice were polyfunctional and mediated cytotoxicity...
January 11, 2017: Cell Host & Microbe
https://www.readbyqxmd.com/read/28074030/working-model-of-the-deep-relationships-of-diverse-modern-human-genetic-lineages-outside-of-africa
#4
Mark Lipson, David Reich
A major topic of interest in human prehistory is how the large-scale genetic structure of modern populations outside of Africa was established. Demographic models have been developed that capture the relationships among small numbers of populations or within particular geographical regions, but constructing a phylogenetic tree with gene flow events for a wide diversity of non-Africans remains a difficult problem. Here, we report a model that provides a good statistical fit to allele-frequency correlation patterns among East Asians, Australasians, Native Americans, and ancient western and northern Eurasians, together with archaic human groups...
January 10, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28070826/interaction-of-ethnicity-and-h-pylori-infection-in-the-occurrence-of-microscopic-colitis
#5
Amnon Sonnenberg, Kevin O Turner, Robert M Genta
BACKGROUND: Previous studies found that microscopic colitis is inversely associated with Helicobacter pylori infection and that microscopic colitis is characterized by a marked ethnic variation. AIM: The aim of the present study was to test whether an underlying ethnic variation of H. pylori infection is responsible for the ethnic variation of microscopic colitis. METHODS: The Miraca Life Sciences Database is a large national electronic repository of histopathologic records of patients distributed throughout the entire USA...
January 9, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28069777/an-african-origin-of-the-eurylaimides-passeriformes-and-the-successful-diversification-of-the-ground-foraging-pittas-pittidae
#6
Alexandre Pedro Selvatti, Ana Galvão, Anieli Guirro Pereira, Luiz Pedreira Gonzaga, Claudia Augusta de Moraes Russo
The Eurylaimides is one of the few passerine groups with a pantropical distribution. In this study, we generated a multi-calibrated tree with 83% of eurylaimid species diversity based on 30 molecular loci. Particular attention was given to the monotypic Sapayoidae to reconstruct the biogeography of this radiation. We conducted several topological tests including nonoverlapping subsampling of the concatenated alignment and coalescent species tree reconstruction. These tests firmly placed the South American Sapayoidae as the sister group to all other Eurylaimides families (split at ∼28 Ma), with increasing branch support as highly variable sites were removed...
November 14, 2016: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28068537/the-immigrant-paradox-on-internalizing-symptoms-among-immigrant-adolescents
#7
Anica G Bowe
Understanding the immigrant paradox on health outcomes among UK's immigrant adolescents will greatly complement the research on immigrants that has already been established there by economists and interdisciplinary fields. This study used the first Longitudinal Study of Young People in England 2004-2010 database (N = 15,770) to determine a) whether there was evidence of the immigrant paradox on internalizing mental health symptoms between first generation (n = 753) and second plus generation (n = 3042) 14/15 year old immigrant adolescents in England and b) whether differences (if any) were moderated by ethnicity group membership (Black African, Black Caribbean, Indian, Pakistani, Bangladeshi, Asian Other, White Immigrant)...
January 6, 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/28066905/implications-of-genital-mutilation-at-autopsy
#8
Roger W Byard
Given the potential significance of mutilation of the external genitalia in medicolegal fatalities, a review of the literature was undertaken to identify subcategories. Such mutilations may have been sustained sometime before death, around the time of death, or after death. The most common type of ante mortem genital mutilations involves cultural practices such as male circumcision. Less common male mutilations such as subincisions are tribally based. Female genital mutilation is found particularly in African, Middle Eastern, or Asian populations...
January 9, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28066841/community-based-participatory-research-studies-on-hiv-aids-prevention-2005-2014
#9
Steven S Coughlin
The recent literature on community-based participatory research (CBPR) approaches to preventing HIV infection in diverse communities was systematically reviewed as part of the planning process for a new study. Published HIV prevention studies that employed CBPR methods were identified for the period January 1, 2005 to April 30, 2014 using PubMed databases and MeSH term and keyword searches. A total of 44 studies on CBPR and HIV or AIDS prevention were identified, of which 3 focused on adolescents, 33 on adults, and 8 on both adolescents and adults...
April 2016: Jacobs Journal of Community Medicine
https://www.readbyqxmd.com/read/28065415/two-sympatric-types-of-plasmodium-ovale-and-discrimination-by-molecular-methods
#10
REVIEW
Myo Thura Zaw, Zaw Lin
Plasmodium ovale is widely distributed in tropical countries, whereas it has not been reported in the Americas. It is not a problem globally because it is rarely detected by microscopy owing to low parasite density, which is a feature of clinical ovale malaria. P.o. curtisi and P.o. wallikeri are widespread in both Africa and Asia, and were known to be sympatric in many African countries and in southeast Asian countries. Small subunit ribosomal RNA (SSUrRNA) gene, cytochrome b (cytb) gene, and merozoite surface protein-1 (msp-1) gene were initially studied for molecular discrimination of P...
December 18, 2016: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28063412/spectral-characterisation-antiviral-activities-in-silico-admet-and-molecular-docking-of-the-compounds-isolated-from-tectona-grandis-to-chikungunya-virus
#11
Sangeetha K, Indu Purushothaman, Rajarajan S
Chikungunya infection is treated symptomatically with antipyretics and anti-inflammatory drugs without any specific antiviral drug till date. The lack of an approved antiviral drug and the emergence of virulent strains after 2006 epidemics emphasize the need for the development of potential antiviral drugs to Chikungunya virus. Hence, we studied the antiviral activity of the extracts and compounds isolated from Tectona grandis leaves to both the Asian and East central South African strains of Chikungunya virus...
January 4, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28061832/high-rates-of-multidrug-resistant-and-rifampicin-resistant-tuberculosis-among-re-treatment-cases-where-do-they-come-from
#12
Romain Ragonnet, James M Trauer, Justin T Denholm, Ben J Marais, Emma S McBryde
BACKGROUND: Globally 3.9% of new and 21% of re-treatment tuberculosis (TB) cases are multidrug-resistant or rifampicin-resistant (MDR/RR), which is often interpreted as evidence that drug resistance results mainly from poor treatment adherence. This study aims to assess the respective contributions of the different causal pathways leading to MDR/RR-TB at re-treatment. METHODS: We use a simple mathematical model to simulate progression between the different stages of disease and treatment for patients diagnosed with TB...
January 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28060549/characterization-of-spirituality-in-maternal-child-caregivers
#13
Katherine Coughlin, Amy Mackley, Rachel Kwadu, Vanessa Shanks, Wendy Sturtz, David Munson, Ursula Guillen
OBJECTIVE: To characterize spiritual beliefs and support provided by maternal-child staff at three academic hospitals. BACKGROUND: Parents in neonatal intensive care units (NICUs) believe that addressing spirituality is important. The spiritual beliefs and the support provided by NICU staff are currently unknown. METHODS: This prospective study surveyed all maternal-child staff (NICU and Obstetrics): physicians, neonatal nurse practitioners, physician assistants, nurses, respiratory therapists, and social workers...
January 6, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28057889/association-between-il-13-1923c-t-polymorphism-and-asthma-risk-a-meta-analysis-based-on-26-case-control-studies
#14
Yueli Xu, Junjuan Li, Zhaolei Ding, Juan Li, Bin Li, Zhengang Yu, Wei Tan
Asthma is a serious and hereditary respiratory disorder affecting all age groups. Interleukin (IL)-13 is a central regulator of allergic inflammation. The purpose of this study was to estimate the relationship between IL-13 +1923C/T polymorphism and asthma susceptibility. Relevant case-control studies published between January 2000 and July 2016 were searched in the online databases. Review Manage (RevMan) 5.3 was used to conduct the statistical analysis. The pooled odds ratio (OR) with its 95% confidence interval (CI) was employed to calculate the strength of association...
January 5, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28051889/race-ethnicity-in-medical-education-an-analysis-of-a-question-bank-for-step-1-of-the-united-states-medical-licensing-examination
#15
Kelsey Ripp, Lundy Braun
: Phenomenon: There is growing concern over racial/ethnic bias in clinical care, yet how best to reduce bias remains challenging, in part because the sources of bias in medical education are poorly understood. One possible source is the routinized use of race/ethnicity in lectures, assessment, and preparatory materials, including question banks for licensing examinations. Because students worldwide use question banks to prepare for the United States Medical Licensing Examination, we examined how race/ethnicity was used in one of the most commonly recommended question banks...
January 4, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28050886/evaluation-of-cortisol-and-telomere-length-measurements-in-ethnically-diverse-women-with-breast-cancer-using-culturally-sensitive-methods
#16
Julio Ramirez, May Elmofty, Esperanza Castillo, Mindy DeRouen, Salma Shariff-Marco, Laura Allen, Scarlett Lin Gomez, Anna María Nápoles, Leticia Márquez-Magaña
The under-representation of ethnic minority participants, who are more likely to be socially disadvantaged in biomedical research, limits generalizability of results and reductions in health disparities. To facilitate investigations of how social disadvantage "gets under the skin," this pilot study evaluated low-intensity methods for collecting hair and saliva samples from multiethnic breast cancer survivors (N = 70) and analysis of biomarkers of chronic stress (cortisol levels) and biological age (telomere length)...
January 3, 2017: Journal of Community Genetics
https://www.readbyqxmd.com/read/28045464/variability-of-128-schizophrenia-associated-gene-variants-across-distinct-ethnic-populations
#17
K Ohi, T Shimada, T Yasuyama, T Uehara, Y Kawasaki
Schizophrenia is a common polygenetic disease affecting 0.5-1% of individuals across distinct ethnic populations. PGC-II, the largest genome-wide association study investigating genetic risk factors for schizophrenia, previously identified 128 independent schizophrenia-associated genetic variants (GVs). The current study examined the genetic variability of GVs across ethnic populations. To assess the genetic variability across populations, the 'variability indices' (VIs) of the 128 schizophrenia-associated GVs were calculated...
January 3, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28043858/infectivity-of-symptomatic-and-asymptomatic-plasmodium-vivax-infections-to-a-southeast-asian-vector-anopheles-dirus
#18
Kirakorn Kiattibutr, Wanlapa Roobsoong, Patchara Sriwichai, Teerawat Saeseu, Nattawan Rachaphaew, Chayanut Suansomjit, Sureemas Buates, Thomas Obadia, Ivo Mueller, Liwang Cui, Wang Nguitragool, Jetsumon Sattabongkot
Plasmodium vivax is now the predominant species causing malarial infection and disease in most non-African areas, but little is known about its transmission efficiency from human to mosquitoes. Because the majority of Plasmodium infections in endemic areas are low density and asymptomatic, it is important to evaluate how well these infections transmit. Using membrane feeding apparatus, Anopheles dirus were fed with blood samples from 94 individuals who had natural P. vivax infections with parasitemias spanning four orders of magnitude...
December 30, 2016: International Journal for Parasitology
https://www.readbyqxmd.com/read/28042387/colorectal-cancer-screening-opportunities-to-improve-uptake-outcomes-and-disparities
#19
REVIEW
Neal Shahidi, Winson Y Cheung
Colorectal cancer screening has become a standard of care in industrialized nations for those 50 to 75 years of age, along with selected high-risk populations. While colorectal cancer screening has been shown to reduce both the incidence and mortality of colorectal cancer, it is a complex multi-disciplinary process with a number of important steps that require optimization before tangible improvements in outcomes are possible. For both opportunistic and programmatic colorectal cancer screening, poor participant uptake remains an ongoing concern...
December 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28041605/racial-and-ethnic-diversity-of-u-s-plastic-surgery-trainees
#20
Jason Silvestre, Joseph M Serletti, Benjamin Chang
BACKGROUND: Increased diversity of U.S. physicians can improve patient communication and mitigate health disparities for racial minorities. This study analyzes trends in racial and ethnic diversity of plastic surgery residents. METHODS: Demographic data of surgical residents, medical students, and integrated plastic surgery residency applicants were obtained from the Association of American Medical Colleges. Data for college students and the general population were obtained from the U...
January 2017: Journal of Surgical Education
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