keyword
MENU ▼
Read by QxMD icon Read
search

Plant model* function*

keyword
https://www.readbyqxmd.com/read/28927046/celastrus-orbiculatus-extract-suppresses-the-epithelial-mesenchymal-transition-by-mediating-cytoskeleton-rearrangement-via-inhibition-of-the-cofilin-1-signaling-pathway-in-human-gastric-cancer
#1
Haibo Wang, Hao Gu, Jun Feng, Yayun Qian, Lin Yang, Feng Jin, Xuanyi Wang, Jue Chen, Youyang Shi, Songhua Lu, Min Zhao, Yanqing Liu
Celastrus orbiculatus is a traditional medicinal plant used in the anti-inflammatory and analgesic treatment of various diseases. A previous study demonstrated that ethyl acetate extract of C. orbiculatus (COE) exhibited significant antitumor effects. However, studies concerning the effects and mechanism of COE in terms of suppressing the epithelial-mesenchymal transition (EMT) in human gastric adenocarcinoma cells have not been performed at present. The present study hypothesized that COE may inhibit EMT in gastric adenocarcinoma cells by regulating cell cytoskeleton rearrangement...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28924726/overexpression-of-the-transcription-factor-nf-yc9-confers-abscisic-acid-hypersensitivity-in-arabidopsis
#2
Chao Bi, Yu Ma, Xiao-Fang Wang, Da-Peng Zhang
Nuclear factor Y (NF-Y) family proteins are involved in many developmental processes and responses to environmental cues in plants, but whether and how they regulate phytohormone abscisic acid (ABA) signaling need further studies. In the present study, we showed that over-expression of the NF-YC9 gene confers ABA hypersensitivity in both the early seedling growth and stomatal response, while down-regulation of NF-YC9 does not affect ABA response in these processes. We also showed that over-expression of the NF-YC9 gene confers salt and osmotic hypersensitivity in early seedling growth, which is likely to be directly associated with the ABA hypersensitivity...
September 18, 2017: Plant Molecular Biology
https://www.readbyqxmd.com/read/28924387/activation-of-nrf2-attenuates-pulmonary-vascular-remodeling-via-inhibiting-endothelial-to-mesenchymal-transition-an-insight-from-a-plant-polyphenol
#3
Yucai Chen, Tianyi Yuan, Huifang Zhang, Yu Yan, Danshu Wang, Lianhua Fang, Yang Lu, Guanhua Du
The endothelial-to-mesenchymal transition (EndMT) has been demonstrated to be involved in pulmonary vascular remodeling. It is partly attributed to oxidative and inflammatory stresses in endothelial cells. In current study, we conducted a series of experiments to clarify the effect of salvianolic acid A (SAA), a kind of polyphenol compound, in the process of EndMT in human pulmonary arterial endothelial cells and in vivo therapeutic efficacy on vascular remodeling in monocrotaline (MCT)-induced EndMT. EndMT was induced by TGFβ1 in human pulmonary arterial endothelial cells (HPAECs)...
2017: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/28923004/regulatory-networks-underlying-mycorrhizal-development-delineated-by-genome-wide-expression-profiling-and-functional-analysis-of-the-transcription-factor-repertoire-of-the-plant-symbiotic-fungus-laccaria-bicolor
#4
Y Daguerre, E Levati, J Ruytinx, E Tisserant, E Morin, A Kohler, B Montanini, S Ottonello, A Brun, C Veneault-Fourrey, F Martin
BACKGROUND: Ectomycorrhizal (ECM) fungi develop a mutualistic symbiotic interaction with the roots of their host plants. During this process, they undergo a series of developmental transitions from the running hyphae in the rhizosphere to the coenocytic hyphae forming finger-like structures within the root apoplastic space. These transitions, which involve profound, symbiosis-associated metabolic changes, also entail a substantial transcriptome reprogramming with coordinated waves of differentially expressed genes...
September 18, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28922769/psb33-sustains-photosystem-ii-d1-protein-under-fluctuating-light-conditions
#5
Rikard Fristedt, Andrea Trotta, Marjaana Suorsa, Anders K Nilsson, Roberta Croce, Eva-Mari Aro, Björn Lundin
On Earth, solar irradiance varies as the sun rises and sets over the horizon, and sunlight is thus in constant fluctuation, following a slow dark-low-high-low-dark curve. Optimal plant growth and development are dependent on the capacity of plants to acclimate and regulate photosynthesis in response to these changes of light. Little is known of regulative processes for photosynthesis during nocturnal events. The nucleus-encoded plant lineage-specific protein PSB33 has been described as stabilizing the photosystem II complex, especially under light stress conditions, and plants lacking PSB33 have a dysfunctional state transition...
July 10, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28922752/current-understanding-of-the-pathways-of-flavonoid-biosynthesis-in-model-and-crop-plants
#6
Takayuki Tohge, Leonardo Perez de Souza, Alisdair R Fernie
Flavonoids are a signature class of secondary metabolites formed from a relatively simple collection of scaffolds. They are extensively decorated by chemical reactions including glycosylation, methylation, and acylation. They are present in a wide variety of fruits and vegetables and as such in Western populations it is estimated that 20-50 mg of flavonoids are consumed daily per person. In planta they have demonstrated to contribute to both flower color and UV protection. Their consumption has been suggested to presenta wide range of health benefits...
July 10, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28920601/dynamics-of-coherence-localization-and-excitation-transfer-in-disordered-nanorings
#7
Alejandro D Somoza, Ke-Wei Sun, Rafael A Molina, Yang Zhao
Self-assembled supramolecular aggregates are excellent candidates for the design of efficient excitation transport devices. Both artificially prepared and natural photosynthetic aggregates in plants and bacteria present an important degree of disorder that is supposed to hinder excitation transport. Besides, molecular excitations couple to nuclear motion affecting excitation transport in a variety of ways. We present an exhaustive study of exciton dynamics in disordered nanorings with long-range interactions under the influence of a phonon bath taking the LH2 system of purple bacteria as a model...
September 18, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28920559/functional-mechanics-of-a-pectin-based-pleural-sealant-after-lung-injury
#8
Andrew B Servais, Cristian D Valenzuela, Arne Kienzle, Alexandra B Ysasi, Willi L Wagner, Akira Tsuda, Maximilian Ackermann, Steven J Mentzer
Pleural injury and associated air leaks are a major influence on patient morbidity and health care costs after lung surgery. Pectin, a plant-derived heteropolysaccharide, has recently demonstrated potential as an adhesive binding to the glycocalyx of visceral mesothelium. Since bioadhesion is a process likely involving the interpenetration of the pectin-based polymer with the glycocalyx, we predicted that the pectin-based polymer may also be an effective sealant for pleural injury. To explore the potential role of an equal weight % mixture of high-methoxyl pectin and carboxymethylcellulose as a pleural sealant, we compared the yield strength of the pectin-based polymer to commonly available surgical products...
September 16, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28918123/carnosic-acid-induces-apoptosis-of-hepatocellular-carcinoma-cells-via-ros-mediated-mitochondrial-pathway
#9
Xinrui Zhang, Yiling Chen, Guangsheng Cai, Xin Li, Di Wang
Carnosic acid (CA), an important bioactive phenolic diterpene mainly found in labiate plants, exerts various biological functions, including antioxidant, anti-inflammatory, antitumor, and neuroprotective activities. In the present study, we proved the deleterious effects of CA against hepatocellular carcinoma (HCC) in both in vitro and in vivo models. In vitro, CA significantly decreased cell viability, inhibited cell proliferation and migration, enhanced apoptosis, and increased caspase-3, -8, and -9 activities in HepG2 and SMMC-7721 cells...
September 13, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28917770/applicability-of-the-direct-injection-liquid-chromatographic-tandem-mass-spectrometric-analytical-approach-to-the-sub-ngl-1-determination-of-perfluoro-alkyl-acids-in-waste-surface-ground-and-drinking-water-samples
#10
Lorenzo Ciofi, Lapo Renai, Daniele Rossini, Claudia Ancillotti, Alida Falai, Donatella Fibbi, Maria Concetta Bruzzoniti, José Juan Santana-Rodriguez, Serena Orlandini, Massimo Del Bubba
The applicability of a direct injection UHPLC-MS/MS method for the analysis of several perfluoroalkyl acids (PFAAs) in a wide range of water matrices was investigated. The method is based on the direct injection of 100µL of centrifuged water sample, without any other sample treatment. Very good method detection limits (0.014-0.44ngL(-1)) and excellent intra and inter-day precision (RSD% values in the range 1.8-4.4% and 2.7-5.7%, respectively) were achieved, with a total analysis time of 20min per sample. A high number of samples - i...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28915548/a-spatio-temporal-statistical-model-of-maximum-daily-river-temperatures-to-inform-the-management-of-scotland-s-atlantic-salmon-rivers-under-climate-change
#11
Faye L Jackson, Robert J Fryer, David M Hannah, Colin P Millar, Iain A Malcolm
The thermal suitability of riverine habitats for cold water adapted species may be reduced under climate change. Riparian tree planting is a practical climate change mitigation measure, but it is often unclear where to focus effort for maximum benefit. Recent developments in data collection, monitoring and statistical methods have facilitated the development of increasingly sophisticated river temperature models capable of predicting spatial variability at large scales appropriate to management. In parallel, improvements in temporal river temperature models have increased the accuracy of temperature predictions at individual sites...
September 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28914357/erratum-to-density-dependent-effects-of-larval-dispersal-mediated-by-host-plant-quality-on-populations-of-an-invasive-insect
#12
Adam A Pepi, Hannah J Broadley, Joseph S Elkinton
There was a coding error in the original paper resulting in incorrect model parameter estimates and in some cases incorrect model conclusions. The error was the specification of logistic models (using the glm and glmer functions) in R as cbind (survived, total) instead of cbind (survived, dead). The differences between the originally published and correct models of those affected are detailed.
September 15, 2017: Oecologia
https://www.readbyqxmd.com/read/28913798/agrobacterium-mediated-transformation-of-wheat-using-immature-embryos
#13
Goetz Hensel, Cornelia Marthe, Jochen Kumlehn
Methods of the Agrobacterium-mediated transformation of bread wheat (Triticum aestivum L.) have been improved in recent years so that genetic engineering can be routinely used for functional genomics as well as for wheat breeding. In the protocol described here, immature embryos of the spring-type model genotype Bobwhite SH 98 26 have been used. Preculture and temperature pretreatment of these explants have led to the reproducible generation of transgenic plants at efficiencies between 5 and 15%. Whereas primary transgenic plants regenerated in vitro commonly show reduced fitness and fertility, no apparent variations with regard to morphology and grain set in their transgenic progeny as compared to wild-type counterparts were observed...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28912378/systematic-mutagenesis-of-serine-hydroxymethyltransferase-reveals-essential-role-in-nematode-resistance
#14
Pramod K Kandoth, Shiming Liu, Elizabeth Prenger, Andrew Ludwig, Naoufal Lakhssassi, Robert Heinz, Zhou Zhou, Amanda Howland, Joshua Gunther, Samantha Eidson, Andi Dhroso, Peter Lafayette, Donna Tucker, Sarah Elizabeth Johnson, James Anderson, Alaa Alaswad, Silvia Cianzio, Wayne Allen Parrott, Dmitry Korkin, Khalid Meksem, Melissa G Mitchum
Rhg4 is a major genetic locus that contributes to soybean cyst nematode (SCN) resistance in the Peking-type resistance of soybean, which also requires the rhg1 gene. By map-based cloning and functional genomic approaches, we previously showed that the Rhg4 gene encodes a predicted cytosolic serine hydroxymethyltransferase (GmSHMT08); however, the novel gain of function of GmSHMT08 in SCN resistance remains to be characterized. Using a forward genetic screen, we identified an allelic series of GmSHMT08 mutants that shed new light on the mechanistic aspects of GmSHMT08-mediated resistance...
September 14, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28912215/the-form-and-function-of-channelrhodopsin
#15
REVIEW
Karl Deisseroth, Peter Hegemann
Channelrhodopsins are light-gated ion channels that, via regulation of flagellar function, enable single-celled motile algae to seek ambient light conditions suitable for photosynthesis and survival. These plant behavioral responses were initially investigated more than 150 years ago. Recently, major principles of function for light-gated ion channels have been elucidated by creating channelrhodopsins with kinetics that are accelerated or slowed over orders of magnitude, by discovering and designing channelrhodopsins with altered spectral properties, by solving the high-resolution channelrhodopsin crystal structure, and by structural model-guided redesign of channelrhodopsins for altered ion selectivity...
September 15, 2017: Science
https://www.readbyqxmd.com/read/28911672/rapid-investigation-of-%C3%AE-glucosidase-inhibitory-activity-of-phaleria-macrocarpa-extracts-using-ftir-atr-based-fingerprinting
#16
Sabina Easmin, Md Zaidul Islam Sarker, Kashif Ghafoor, Sahena Ferdosh, Juliana Jaffri, Md Eaqub Ali, Hamed Mirhosseini, Fahad Y Al-Juhaimi, Vikneswari Perumal, Alfi Khatib
Phaleria macrocarpa, known as "Mahkota Dewa", is a widely used medicinal plant in Malaysia. This study focused on the characterization of α-glucosidase inhibitory activity of P. macrocarpa extracts using Fourier transform infrared spectroscopy (FTIR)-based metabolomics. P. macrocarpa and its extracts contain thousands of compounds having synergistic effect. Generally, their variability exists, and there are many active components in meager amounts. Thus, the conventional measurement methods of a single component for the quality control are time consuming, laborious, expensive, and unreliable...
April 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28906105/enantioselective-phytotoxicity-of-dichlorprop-to-arabidopsis-thaliana-effect-of-cytochrome-p450-enzymes-and-role-of-fe
#17
Zunwei Chen, Jia Wang, Hui Chen, Yuezhong Wen, Weiping Liu
The ecotoxicology effects of chiral herbicides have long been recognized and have drawn increasing attention. The toxic mechanisms of herbicides in plants are involved in production of reactive oxygen species (ROS) and cause damage to target enzyme, but the relationship between these two factors in the enantioselectivity of chiral herbicides has rarely been investigated. Furthermore, even though cytochromes P450 enzymes (CYP450s) have been related to the phytotoxicity of herbicides, their roles in the enantioselectivity of chiral herbicides have yet to be explored...
September 14, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28905991/target-of-rapamycin-signaling-orchestrates-growth-defense-trade-offs-in-plants
#18
David De Vleesschauwer, Osvaldo Filipe, Gena Hoffman, Hamed Soren Seifi, Ashley Haeck, Patrick Canlas, Jonas Van Bockhaven, Evelien De Waele, Kristof Demeestere, Pamela Ronald, Monica Hofte
Plant defense to microbial pathogens is often accompanied by significant growth inhibition. How plants merge immune system function with normal growth and development is still poorly understood. Here, we investigated the role of target of rapamycin (TOR), an evolutionary conserved serine/threonine kinase, in the plant defense response. We used rice as a model system and applied a combination of chemical, genetic, genomic and cell-based analyses. We demonstrate that ectopic expression of TOR and Raptor (regulatory-associated protein of mTOR), a protein previously demonstrated to interact with TOR in Arabidopsis, positively regulates growth and development in rice...
September 14, 2017: New Phytologist
https://www.readbyqxmd.com/read/28904554/plants-derived-neuroprotective-agents-cutting-the-cycle-of-cell-death-through-multiple-mechanisms
#19
REVIEW
Taiwo Olayemi Elufioye, Tomayo Ireti Berida, Solomon Habtemariam
Neuroprotection is the preservation of the structure and function of neurons from insults arising from cellular injuries induced by a variety of agents or neurodegenerative diseases (NDs). The various NDs including Alzheimer's, Parkinson's, and Huntington's diseases as well as amyotropic lateral sclerosis affect millions of people around the world with the main risk factor being advancing age. Each of these diseases affects specific neurons and/or regions in the brain and involves characteristic pathological and molecular features...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28900797/improvement-of-chia-seeds-with-antioxidant-activity-gaba-essential-amino-acids-and-dietary-fiber-by-controlled-germination-bioprocess
#20
Mario Armando Gómez-Favela, Roberto Gutiérrez-Dorado, Edith Oliva Cuevas-Rodríguez, Vicente Adrián Canizalez-Román, Claudia Del Rosario León-Sicairos, Jorge Milán-Carrillo, Cuauhtémoc Reyes-Moreno
Chia (Salvia hispanica L.) plant is native from southern Mexico and northern Guatemala. Their seeds are a rich source of bioactive compounds which protect consumers against chronic diseases. Germination improves functionality of the seeds due to the increase in the bioactive compounds and associated antioxidant activity. The purpose of this study was to obtain functional flour from germinated chia seeds under optimized conditions with increased antioxidant activity, phenolic compounds, GABA, essential amino acids, and dietary fiber with respect to un-germinated chia seeds...
September 12, 2017: Plant Foods for Human Nutrition
keyword
keyword
38145
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"