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https://www.readbyqxmd.com/read/29133325/minimally-invasive-surgery-versus-open-surgery-in-the-treatment-of-lumbar-spondylolisthesis-study-protocol-of-a-multicentre-randomised-controlled-trial-misos-trial
#1
Mark P Arts, Jasper Fc Wolfs, Jos Ma Kuijlen, Godard Cw de Ruiter
INTRODUCTION: Patients with symptomatic spondylolisthesis are frequently treated with nerve root decompression, in addition to pedicle screw fixation and interbody fusion. Minimally invasive approaches are gaining attention in recent years, although there is no clear evidence supporting the proclamation of minimally invasive spine surgery (MISS) being better than open surgery. We present the design of the MISOS (Minimal Invasive Surgery versus Open Surgery) trial on the effectiveness of MISS versus open surgery in patients with degenerative or spondylolytic spondylolisthesis...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29133295/head-injury-mechanisms-in-fis-world-cup-alpine-and-freestyle-skiers-and-snowboarders
#2
Sophie Elspeth Steenstrup, Arnhild Bakken, Tone Bere, Declan Alexander Patton, Roald Bahr
INTRODUCTION: Head injuries represent a concern in skiing and snowboarding, with traumatic brain injuries being the most common cause of death. AIM: To describe the mechanisms of head and face injuries among World Cup alpine and freestyle skiers and snowboarders. METHODS: We performed a qualitative analysis of videos obtained of head and face injuries reported through the International Ski Federation Injury Surveillance System during 10 World Cup seasons (2006-2016)...
November 13, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29103367/survey-of-risks-and-benefits-communication-strategies-by-research-nurses
#3
Lika Nusbaum, Brenda Douglas, Neenah Estrella-Luna, Michael Paasche-Orlow, Karla Damus
BACKGROUND: An ethical, informed consent process requires that potential participants understand the study, their rights, and the risks and benefits. Yet, despite strategies to improve communication, many participants still lack understanding of potential risks and benefits. Investigating attitudes and practices of research nurses can identify ways to improve the informed consent process. RESEARCH QUESTION: What are the attitudes, practices, and preparedness of nurses involved in the informed consent process regarding communication of risks and benefits? RESEARCH DESIGN: A survey was developed and administered online to a national purposive sample of 107 research nurses with experience obtaining informed consent for clinical trials...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/29098202/guidance-and-ethical-considerations-for-undertaking-transgender-health-research-and-institutional-review-boards-adjudicating-this-research
#4
REVIEW
Noah Adams, Ruth Pearce, Jaimie Veale, Asa Radix, Danielle Castro, Amrita Sarkar, Kai Cheng Thom
The purpose of this review is to create a set of provisional criteria for Institutional Review Boards (IRBs) to refer to when assessing the ethical orientation of transgender health research proposals. We began by searching for literature on this topic using databases and the reference lists of key articles, resulting in a preliminary set of criteria. We then collaborated to develop the following nine guidelines: (1) Whenever possible, research should be grounded, from inception to dissemination, in a meaningful collaboration with community stakeholders; (2) language and framing of transgender health research should be non-stigmatizing; (3) research should be disseminated back to the community; (4) the diversity of the transgender and gender diverse (TGGD) community should be accurately reflected and sensitively reflected; (5) informed consent must be meaningful, without coercion or undue influence; (6) the protection of participant confidentiality should be paramount; (7) alternative consent procedures should be considered for TGGD minors; (8) research should align with current professional standards that refute conversion, reorientation, or reparative therapy; and (9) IRBs should guard against the temptation to avoid, limit, or delay research on this subject...
2017: Transgender Health
https://www.readbyqxmd.com/read/29061616/transforaminal-lumbar-interbody-fusion-with-cortical-bone-trajectory-screws-versus-traditional-pedicle-screws-fixation-a-study-protocol-of-randomised-controlled-trial
#5
Zhenhua Feng, Xiaobin Li, Qian Tang, Chenggui Wang, Wenhao Zheng, Hui Zhang, Ai-Min Wu, Naifeng Tian, Yaosen Wu, Wenfei Ni
INTRODUCTION: Transforaminal lumbar interbody fusion (TLIF) has been widely used in the treatment of lumbar degenerative disc disorders and shows favourable clinical results. Recently, cortical bone trajectory (CBT) has become a new trajectory for screw insertion in the lumbar spine. Several biomechanical studies have demonstrated that the CBT technique achieves screw purchase and strength greater than the traditional method. Currently, the available data on the clinical effectiveness of the two performed surgeries, TLIF with CBT screws (CBT-TLIF) and TLIF with traditional pedicle screws (PS-TLIF), are insufficient...
October 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29033554/validation-of-the-italian-version-of-the-patient-reported-experience-measures-for-intermediate-care-services
#6
Sergio Cinocca, Paola Rucci, Concetta Randazzo, Elizabeth Teale, Davide Pianori, Emanuele Ciotti, Maria Pia Fantini
BACKGROUND: Intermediate care (IC) services are a key component of integrated care for elderly people, providing a link between hospital and home through provision of rehabilitation and health and social care. The Patient Reported Experience Measures (PREMs) are designed to measure user experience of care in IC settings. OBJECTIVE: To examine the feasibility and the scaling properties of the Italian version of PREMs questionnaires for use in IC services. METHODS: A cross-sectional survey was conducted on consecutive users of 1 home-based and 4 bed-based IC services in Emilia-Romagna (Italy)...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29029551/low-back-pain-investigation-of-biases-in-outpatient-canadian-physical-therapy
#7
Maude Laliberté, Barbara Mazer, Tatiana Orozco, Gevorg Chilingaryan, Bryn Williams-Jones, Matthew Hunt, Debbie Ehrmann Feldman
Background: Previous research suggested that physical therapy services can be influenced by patient characteristics (age, sex, socioeconomic status) or insurance status rather than their clinical need. Objective: The aim of this study was to determine whether patient-related factors (age, sex, SES) and the source of reimbursement for physical therapy services (insurance status) influence wait time for, frequency of, and duration of physical therapy for low back pain...
October 1, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29025132/most-relevant-neuropathic-pain-treatment-and-chronic-low-back-pain-management-guidelines-a-change-pain-latin-america-advisory-panel-consensus
#8
Cesar Amescua-Garcia, Frantz Colimon, Carlos Guerrero, Aziza Jreige Iskandar, Maria Berenguel Cook, Patricia Bonilla, Durval Campos Kraychete, William Delgado Barrera, Jose Alberto Flores Cantisani, John Jairo Hernandez-Castro, Argelia Lara-Solares, Concepcion Perez Hernandez, Maria Antonieta Rico, Maria Del Rocio Guillen Nunez, Manuel Sempertegui Gallegos, Joao Batista Santos Garcia
Objective: Chronic pain conditions profoundly affect the daily living of a significant number of people and are a major economic and social burden, particularly in developing countries. The Change Pain Latin America (CPLA) advisory panel aimed to identify the most appropriate guidelines for the treatment of neuropathic pain (NP) and chronic low back pain (CLBP) for use across Latin America. Methods: Published systematic reviews or practice guidelines were identified by a systematic search of PubMed, the Guidelines Clearinghouse, and Google...
August 24, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28962911/from-the-international-space-station-to-the-clinic-how-prolonged-unloading-may-disrupt-lumbar-spine-stability
#9
Jeannie F Bailey, Stephanie L Miller, Kristine Khieu, Conor W O'Neill, Robert M Healey, Dezba G Coughlin, Jojo V Sayson, Douglas G Chang, Alan R Hargens, Jeffrey C Lotz
Background context Prolonged microgravity exposure is associated with localized low back pain and an elevated risk of post-flight disc herniation. Though the mechanisms by which microgravity impairs the spine are unclear, they should be foundational for developing in-flight countermeasures for maintaining astronaut spine health. Because human spine anatomy has adapted to upright posture on Earth, observations of how spaceflight affects the spine should also provide new and potentially important information on spine biomechanics that benefit the general population...
September 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28945896/patients-with-high-pelvic-tilt-achieve-the-same-clinical-success-as-those-with-low-pelvic-tilt-after-minimally-invasive-adult-deformity-surgery
#10
Juan S Uribe, Jacob Januszewski, Michael Wang, Neel Anand, David O Okonkwo, Praveen V Mummaneni, Stacie Nguyen, Joseph Zavatsky, Khoi Than, Pierce Nunley, Paul Park, Adam S Kanter, Frank La Marca, Richard Fessler, Gregory M Mundis, Robert K Eastlack
BACKGROUND: Pelvic tilt (PT) is a compensatory mechanism for adult spinal deformity patients to mitigate sagittal imbalance. The association between preop PT and postop clinical and radiographic outcomes has not been well studied in patients undergoing minimally invasive adult deformity surgery. OBJECTIVE: To evaluate clinical and radiographic outcomes in adult spinal deformity patients with high and low preoperative PT treated surgically using less invasive techniques...
August 17, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28934790/factors-associated-with-successful-responses-to-transforaminal-balloon-adhesiolysis-for-chronic-lumbar-foraminal-stenosis-retrospective-study
#11
Doo Hwan Kim, Seong-Sik Cho, Yeon-Jin Moon, Koo Kwon, Kunhee Lee, Jeong-Gil Leem, Jin-Woo Shin, Ji Hyun Park, Seong-Soo Choi
BACKGROUND: Recently, transforaminal balloon adhesiolysis was introduced to manage patients with chronic radicular pain occurring with or without low back pain. However, the factors associated with successful responses to transforaminal balloon adhesiolysis are not known. OBJECTIVE: To evaluate the factors associated with successful responses to transforaminal balloon adhesiolysis for chronic lumbar spinal stenosis. STUDY DESIGN: This is a retrospective observational study...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28916008/preparing-trainees-for-integrated-care-triple-board-and-the-postpediatric-portal-program
#12
REVIEW
Mary Margaret Gleason, Sandra Sexson
Training combining the disciplines of pediatrics, psychiatry, and child and adolescent psychiatry dates back to World War II, but formal combined programs began more than 3 decades ago as the Triple Board Program and 10 years ago as the Postpediatric Portal Program (PPPP). Triple board training was rigorously examined as a pilot program and ongoing surveys suggest that it provides successful training of physicians who can pass the required board examinations and contribute to clinical, academic, and administrative/advocacy endeavors...
October 2017: Child and Adolescent Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/28913382/psychometric-properties-of-the-persian-version-of-the-patient-rated-wris-t-evaluation
#13
Golnaz Ghayyem Hassankhani, Ali Moradi, Ehsan Vahedi, Sayyed Hadi Sayyed Hoseinian, Zohreh Jahani, Maedeh Rahmani, Mohammad H Ebrahimzadeh
BACKGROUND: The patient-rated wrist evaluation (PRWE) score is one of the most common clinical instruments used as an outcome measurement tool for distal radius fractures and other upper extremity conditions. The purpose of this study was to translate the PRWE into its Persian version and to evaluate its validity and reliability in patients with upper extremity conditions. METHODS: One hundred and fourthly one adult patients with upper extremity conditions participated in this ethical board approved study from August 2015 to May 2016...
July 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/28891217/reproducibility-of-f18-fdg-pet-radiomic-features-for-different-cervical-tumor-segmentation-methods-gray-level-discretization-and-reconstruction-algorithms
#14
Baderaldeen A Altazi, Geoffrey G Zhang, Daniel C Fernandez, Michael E Montejo, Dylan Hunt, Joan Werner, Matthew C Biagioli, Eduardo G Moros
Site-specific investigations of the role of radiomics in cancer diagnosis and therapy are emerging. We evaluated the reproducibility of radiomic features extracted from (18) Flourine-fluorodeoxyglucose ((18) F-FDG) PET images for three parameters: manual versus computer-aided segmentation methods, gray-level discretization, and PET image reconstruction algorithms. Our cohort consisted of pretreatment PET/CT scans from 88 cervical cancer patients. Two board-certified radiation oncologists manually segmented the metabolic tumor volume (MTV1 and MTV2 ) for each patient...
September 11, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28889403/do-paediatric-investigation-plans-pips-advance-paediatric-healthcare
#15
Klaus Rose, Philip D Walson
Since 2007, new drugs need a paediatric investigation plan (PIP) for EU registration. The PIPs' justifications can be traced back to concerns expressed by Shirkey that label warnings against paediatric use made children "therapeutic orphans", and the American Academy of Pediatrics' claim that all children differ considerably from adults. US legislation first encouraged, then also required, separate, adult-style safety and efficacy studies in all paediatric subpopulations. This triggered paediatric regulatory studies by the pharmaceutical industry...
December 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28861052/expose-r2-the-astrobiological-esa-mission-on-board-of-the-international-space-station
#16
Elke Rabbow, Petra Rettberg, Andre Parpart, Corinna Panitz, Wolfgang Schulte, Ferdinand Molter, Esther Jaramillo, René Demets, Peter Weiß, Rainer Willnecker
On July 23, 2014, the Progress cargo spacecraft 56P was launched from Baikonur to the International Space Station (ISS), carrying EXPOSE-R2, the third ESA (European Space Agency) EXPOSE facility, the second EXPOSE on the outside platform of the Russian Zvezda module, with four international astrobiological experiments into space. More than 600 biological samples of archaea, bacteria (as biofilms and in planktonic form), lichens, fungi, plant seeds, triops eggs, mosses and 150 samples of organic compounds were exposed to the harsh space environment and to parameters similar to those on the Mars surface...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28857692/cultural-adaptation-of-a-supportive-care-needs-measure-for-hispanic-men-cancer-survivors
#17
Dinorah Martinez Tyson, Patricia Medina-Ramirez, Coralia Vázquez-Otero, Clement K Gwede, Margarita Bobonis, Susan C McMillan
OBJECTIVE: Research with ethnic minority populations requires instrumentation that is cultural and linguistically relevant. The aim of this study was to translate and culturally adapt the Cancer Survivor Unmet Needs measure into Spanish. METHODS: We describe the iterative, community-engaged consensus-building approaches used to adapt the instrument for Hispanic male cancer survivors. We used an exploratory sequential mixed method study design. Methods included translation and back-translation, focus groups with cancer survivors (n = 18) and providers (n = 5), use of cognitive interview techniques to evaluate the comprehension and acceptability of the adapted instrument with survivors (n = 12), ongoing input from the project's community advisory board, and preliminary psychometric analysis (n = 84)...
August 31, 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/28836313/gene-therapy-for-heart-failure-time-to-go-back-to-the-drawing-board
#18
EDITORIAL
Barry Greenberg
No abstract text is available yet for this article.
August 24, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28818047/second-opinion-for-degenerative-spinal-conditions-an-option-or-a-necessity-a-prospective-observational-study
#19
Mario Lenza, Rachelle Buchbinder, Margaret P Staples, Oscar F P Dos Santos, Reynaldo A Brandt, Claudio L Lottenberg, Miguel Cendoroglo, Mario Ferretti
BACKGROUND: Second opinions may improve quality of patient care. The primary objective of this study was to determine the concordance between first and second diagnoses and opinions regarding need for spinal surgery among patients with back or neck pain that have been recommended spinal surgery. METHODS: We performed a prospective observational study of patients who had been recommended for spinal surgery and received a second opinion between May 2011 and May 2012 at the Hospital Israelita Albert Einstein on the advice of their health insurance company...
August 17, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28754110/predictors-of-health-care-drop-out-in-an-inception-cohort-of-patients-with-early-onset-rheumatoid-arthritis
#20
Irazú Contreras-Yáñez, Virginia Pascual-Ramos
BACKGROUND: RA patients who eventually dropped out of treatment and out of the health care system had potentially disastrous consequences for their health-related quality-of-life outcomes. Objectives of the study were to identify predictors of health care drop out (HDO) in an inception and ongoing cohort of patients with recent onset RA. METHODS: Charts from patients attending an early arthritis clinic from February 2004 to December 2015, and standardized follow-up evaluations were reviewed...
July 28, 2017: BMC Musculoskeletal Disorders
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