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https://www.readbyqxmd.com/read/29331975/is-postoperative-bracing-after-pedicle-screw-fixation-of-spine-fractures-necessary-study-protocol-of-the-ornot-study-a-randomised-controlled-multicentre-trial
#1
Arjen Johannes Smits, Jaap Deunk, Agnita Stadhouder, Mark Cornelis Altena, Diederik Hendrik Ruth Kempen, Frank Willem Bloemers
INTRODUCTION: The most common surgical treatment of traumatic spine fractures is through a posterior approach using pedicle screws and rods. Postoperative treatment protocols including the use of postoperative orthoses however differ between hospitals and surgeons. A three-point hyperextension orthosis is designed to support proper posture and unload the anterior column. Some motion remains when wearing an orthosis, and its main value in postoperative treatment is therefore believed to be pain relief and patient confidence...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29301780/multiparametric-analysis-of-permeability-and-adc-histogram-metrics-for-classification-of-pediatric-brain-tumors-by-tumor-grade
#2
S Vajapeyam, D Brown, P R Johnston, K I Ricci, M W Kieran, H G W Lidov, T Y Poussaint
BACKGROUND AND PURPOSE: Accurate tumor grading is essential for treatment planning of pediatric brain tumors. We hypothesized that multiparametric analyses of a combination of permeability metrics and ADC histogram metrics would differentiate high- and low-grade tumors with high accuracy. MATERIALS AND METHODS: DTI and dynamic contrast-enhanced MR imaging using T1-mapping with flip angles of 2°, 5°, 10°, and 15°, followed by a 0.1-mmol/kg body weight gadolinium-based bolus was performed on all patients in addition to standard MR imaging...
January 4, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29280771/effects-of-the-new-york-state-workers-compensation-board-medical-treatment-guidelines-on-return-to-work
#3
Cristina Demian, Bruce Barron, Anthony Almudevar
OBJECTIVE: Examine the association between New York State Workers' Compensation Medical Treatment Guidelines (Guidelines) adherence and return-to-work after occupational low back injuries. Assess adherence to Guidelines by examining diagnostic and treatment utilization. METHOD: Retrospective chart review of cases. Outcomes of interest were lost time duration and diagnostic/treatment utilization rates. Time to event analyses performed using Kaplan Meier plots and Cox proportional hazard model...
December 26, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29261541/the-medical-school-admissions-process-and-meeting-the-public-s-health-care-needs-never-the-twain-shall-meet
#4
Jennifer Cleland
Medical schools typically assess how good their selection process is using metrics such as students' assessment performance and the academic success of alumni on later indicators of academic ability and clinical competence, such as Royal College of Physicians or specialty board examinations. To address global issues with the maldistribution of doctors and increasing numbers of new medical school graduates choosing not to work in a clinical context requires different measurements of medical school admissions processes, like those related to graduates' career outcomes (e...
December 19, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29251703/a-pilot-registry-of-trauma-surgeons-willing-and-ready-to-respond-to-disasters
#5
Daniel Grabo, Aaron Strumwasser, Kyle Remick, Susan Briggs
BACKGROUND: A well-defined means of organizing surgeons based on functional capabilities in disaster response has been lacking. We sought to create a pilot registry of surgeons, organized by functional capacities, available to respond to disasters in conjunction with the American College of Surgeons Operation Giving Back and to better understand their participation in disaster medicine training. METHODS: The authors conducted a survey of the members of the American Association for the Surgery of Trauma and the Eastern Association for the Surgery of Trauma aimed at establishing a pilot registry of qualified trauma surgeons available to respond to disasters...
December 14, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29245341/case-report-on-the-role-of-radiofrequency-assisted-spleen-preserving-surgery-for-splenic-metastasis-in-the-era-of-check-point-inhibitors
#6
Satvinder Mudan, Jayant Kumar, Neves C Mafalda, Tomokazu Kusano, Isabella Reccia, Artur Zanallato, Angus Dalgleish, Nagy Habib
RATIONALE: An isolated splenic metastasis is a rare phenomenon noted in advanced stage melanoma. We report the role of radiofrequency (RF) -based splenic-preserving splenectomy in a patient with a solitary splenic metastasis from advanced stage melanoma that was managed with checkpoint inhibitors. PATIENT CONCERNS: We report a case of a 60-year-old man who presented with multiple lung metastases and a solitary splenic metastasis with advanced stage melanoma following excision of primary from his trunk 2...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29236920/brazilian-version-of-the-cognitive-failures-questionnaire-cfq-cross-cultural-adaptation-and-evidence-of-validity-and-reliability
#7
Jonas J de Paula, Danielle S Costa, Débora M de Miranda, Marco A Romano-Silva
OBJECTIVE: Cognitive failures are simple mistakes in routine activities, such as forgetting commitments and experiencing difficulty concentrating. The Cognitive Failures Questionnaire (CFQ) was designed to assess the frequency of these errors in everyday life. Although widely used in psychiatry and psychology, both in clinical and research settings, it has not been adapted for use in Brazil. Our objective was to perform cross-cultural adaptation of the CFQ for the Brazilian reality and assess its validity and reliability...
December 11, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/29234924/a-new-direction-in-anastomotic-research-should-we-redesign-the-angle-of-sorrow
#8
Omar E Aly
INTRODUCTION: Despite advances in oncological outcomes in colo-rectal surgery, rates of anastomotic leak have not improved. The precise mechanisms of anastomotic leak remain poorly understood. Current research has focused on anastomotic reinforcement to tackle anastomotic leak with little success. The 'Angle of Sorrow', the corner of the anastomosis is prone to anastomotic leak, but remains a persistent feature in the gastrointestinal anastomosis. The tendency for stress forces to concentrate in the vulnerable 'Angle of Sorrow' prompts the need for anastomotic design research...
December 12, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29216808/welcome-to-volume-9-of-therapeutic-delivery
#9
Hannah Makin
Happy New Year to all of our readers! Welcome to volume 9 of Therapeutic Delivery. We would like to take the opportunity to look back over 2017, which was another excellent year for us. We thank all our readers, reviewers, authors and Editorial Board members for their continued support and very much look forward to working with all our contributors again in 2018.
January 2018: Therapeutic Delivery
https://www.readbyqxmd.com/read/29197902/a-new-zealand-platform-to-enable-genetic-investigation-of-adverse-drug-reactions
#10
Simran Ds Maggo, Eng Wee Chua, Paul Chin, Simone Cree, John Pearson, Matthew Doogue, Martin A Kennedy
A multitude of factors can affect drug response in individuals. It is now well established that variations in genes, especially those coding for drug metabolising enzymes, can alter the pharmacokinetic and/or pharmacodynamic profile of a drug, impacting on efficacy and often resulting in drug-induced toxicity. The UDRUGS study is an initiative from the Carney Centre for Pharmacogenomics to biobank DNA and store associated clinical data from patients who have suffered rare and/or serious adverse drug reactions (ADRs)...
December 1, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29192879/pedicle-screw-placement-accuracy-using-ultra-low-radiation-imaging-with-image-enhancement-versus-conventional-fluoroscopy-in-minimally-invasive-transforaminal-lumbar-interbody-fusion-an-internally-randomized-controlled-trial
#11
Gautam Nayar, Daniel J Blizzard, Timothy Y Wang, Steven Cook, Adam G Back, David Vincent, Isaac O Karikari
OBJECTIVE A previous study found that ultra-low radiation imaging (ULRI) with image enhancement significantly decreases radiation exposure by roughly 75% for both the patient and operating room personnel during minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) (p < 0.001). However, no clinical data exist on whether this imaging modality negatively impacts patient outcomes. Thus, the goal of this randomized controlled trial was to assess pedicle screw placement accuracy with ULRI with image enhancement compared with conventional, standard-dose fluoroscopy for patients undergoing single-level MIS-TLIF...
December 1, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29184289/proprioceptive-change-impairs-balance-control-in-older-patients-with-low-back-pain
#12
Tadashi Ito, Yoshihito Sakai, Kazunori Yamazaki, Kazuma Igarashi, Noritaka Sato, Kiyoko Yokoyama, Yoshifumi Morita
[Purpose] This study aims to determine the specific proprioceptive control strategy used during postural balance in older patients with low back pain (LBP) and non-LBP (NLBP) and to assess whether this strategy is related to proprioceptive decline and LBP. [Subjects and Methods] Pressure displacement center was determined in 47 older persons with LBP and 64 older persons with NLBP during upright stance on a balance board without vision. Gastrocnemius (GS) and lumbar multifidus muscle (LM) vibratory stimulations of 60 and 240-Hz, respectively, were applied to evaluate the relative contributions of different proprioceptive signals (relative proprioceptive weighting ratio, RPW) used in postural control...
October 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29164632/characterization-of-nanodot-optically-stimulated-luminescence-detectors-and-high-sensitivity-mcp-n-thermoluminescent-detectors-in-the-40-300-kvp-energy-range
#13
Yannick Poirier, Svetlana Kuznetsova, Jose Eduardo Villarreal-Barajas
PURPOSE: To investigate empirically the energy dependence of the detector response of two in-vivo luminescence detectors, LiF:Mg,Cu,P (MCP-N) high-sensitivity TLDs and Al2 O3 :C OSLDs, in the 40-300-kVp energy range in the context of in-vivo surface dose measurement. As these detectors become more prevalent in clinical and pre-clinical in-vivo measurements, knowledge of the variation of the empirical dependence of the measured response of these detectors across a wide spectrum of beam qualities is important...
November 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/29151051/subclinical-propionibacterium-acnes-infection-estimation-in-the-intervertebral-disc-spine-id-protocol-for-a-prospective-cohort
#14
Nelson Astur, Delio E Martins, Marcelo Wajchenberg, Mario Ferretti, Fernando G Menezes, Andre M Doi, Laercio A Rosemberg, Durval C B Santos, Alexandre S Iutaka, Luciano M R Rodrigues, Marines D V Martino, Jorge R Pagura, Eduardo N Kihara Filho, Mario Lenza
INTRODUCTION: Low back pain and vertebral endplate abnormalities are common conditions within the population. Subclinical infection caused by indolent pathogens can potentially lead to these findings, with differentiation between them notably challenging from a clinical perspective. Progressive infection of the intervertebral disc has been extensively associated with increasing low back pain, with Propionibacterium acnes specifically implicated with in relation to sciatica. The main purpose of this study is to identify if the presence of an infective pathogen within the intervertebral disc is primary or is a result of intraoperative contamination, and whether this correlates to low back pain...
November 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/29133325/minimally-invasive-surgery-versus-open-surgery-in-the-treatment-of-lumbar-spondylolisthesis-study-protocol-of-a-multicentre-randomised-controlled-trial-misos-trial
#15
Mark P Arts, Jasper Fc Wolfs, Jos Ma Kuijlen, Godard Cw de Ruiter
INTRODUCTION: Patients with symptomatic spondylolisthesis are frequently treated with nerve root decompression, in addition to pedicle screw fixation and interbody fusion. Minimally invasive approaches are gaining attention in recent years, although there is no clear evidence supporting the proclamation of minimally invasive spine surgery (MISS) being better than open surgery. We present the design of the MISOS (Minimal Invasive Surgery versus Open Surgery) trial on the effectiveness of MISS versus open surgery in patients with degenerative or spondylolytic spondylolisthesis...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29133295/head-injury-mechanisms-in-fis-world-cup-alpine-and-freestyle-skiers-and-snowboarders
#16
Sophie Elspeth Steenstrup, Arnhild Bakken, Tone Bere, Declan Alexander Patton, Roald Bahr
INTRODUCTION: Head injuries represent a concern in skiing and snowboarding, with traumatic brain injuries being the most common cause of death. AIM: To describe the mechanisms of head and face injuries among World Cup alpine and freestyle skiers and snowboarders. METHODS: We performed a qualitative analysis of videos obtained of head and face injuries reported through the International Ski Federation Injury Surveillance System during 10 World Cup seasons (2006-2016)...
November 13, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29103367/survey-of-risks-and-benefits-communication-strategies-by-research-nurses
#17
Lika Nusbaum, Brenda Douglas, Neenah Estrella-Luna, Michael Paasche-Orlow, Karla Damus
BACKGROUND: An ethical, informed consent process requires that potential participants understand the study, their rights, and the risks and benefits. Yet, despite strategies to improve communication, many participants still lack understanding of potential risks and benefits. Investigating attitudes and practices of research nurses can identify ways to improve the informed consent process. RESEARCH QUESTION: What are the attitudes, practices, and preparedness of nurses involved in the informed consent process regarding communication of risks and benefits? RESEARCH DESIGN: A survey was developed and administered online to a national purposive sample of 107 research nurses with experience obtaining informed consent for clinical trials...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/29098202/guidance-and-ethical-considerations-for-undertaking-transgender-health-research-and-institutional-review-boards-adjudicating-this-research
#18
REVIEW
Noah Adams, Ruth Pearce, Jaimie Veale, Asa Radix, Danielle Castro, Amrita Sarkar, Kai Cheng Thom
The purpose of this review is to create a set of provisional criteria for Institutional Review Boards (IRBs) to refer to when assessing the ethical orientation of transgender health research proposals. We began by searching for literature on this topic using databases and the reference lists of key articles, resulting in a preliminary set of criteria. We then collaborated to develop the following nine guidelines: (1) Whenever possible, research should be grounded, from inception to dissemination, in a meaningful collaboration with community stakeholders; (2) language and framing of transgender health research should be non-stigmatizing; (3) research should be disseminated back to the community; (4) the diversity of the transgender and gender diverse (TGGD) community should be accurately reflected and sensitively reflected; (5) informed consent must be meaningful, without coercion or undue influence; (6) the protection of participant confidentiality should be paramount; (7) alternative consent procedures should be considered for TGGD minors; (8) research should align with current professional standards that refute conversion, reorientation, or reparative therapy; and (9) IRBs should guard against the temptation to avoid, limit, or delay research on this subject...
2017: Transgender Health
https://www.readbyqxmd.com/read/29061616/transforaminal-lumbar-interbody-fusion-with-cortical-bone-trajectory-screws-versus-traditional-pedicle-screws-fixation-a-study-protocol-of-randomised-controlled-trial
#19
Zhenhua Feng, Xiaobin Li, Qian Tang, Chenggui Wang, Wenhao Zheng, Hui Zhang, Ai-Min Wu, Naifeng Tian, Yaosen Wu, Wenfei Ni
INTRODUCTION: Transforaminal lumbar interbody fusion (TLIF) has been widely used in the treatment of lumbar degenerative disc disorders and shows favourable clinical results. Recently, cortical bone trajectory (CBT) has become a new trajectory for screw insertion in the lumbar spine. Several biomechanical studies have demonstrated that the CBT technique achieves screw purchase and strength greater than the traditional method. Currently, the available data on the clinical effectiveness of the two performed surgeries, TLIF with CBT screws (CBT-TLIF) and TLIF with traditional pedicle screws (PS-TLIF), are insufficient...
October 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29033554/validation-of-the-italian-version-of-the-patient-reported-experience-measures-for-intermediate-care-services
#20
Sergio Cinocca, Paola Rucci, Concetta Randazzo, Elizabeth Teale, Davide Pianori, Emanuele Ciotti, Maria Pia Fantini
BACKGROUND: Intermediate care (IC) services are a key component of integrated care for elderly people, providing a link between hospital and home through provision of rehabilitation and health and social care. The Patient Reported Experience Measures (PREMs) are designed to measure user experience of care in IC settings. OBJECTIVE: To examine the feasibility and the scaling properties of the Italian version of PREMs questionnaires for use in IC services. METHODS: A cross-sectional survey was conducted on consecutive users of 1 home-based and 4 bed-based IC services in Emilia-Romagna (Italy)...
2017: Patient Preference and Adherence
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