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https://www.readbyqxmd.com/read/28416501/protocol-for-a-placebo-controlled-within-participants-crossover-trial-evaluating-the-efficacy-of-intranasal-oxytocin-to-improve-pain-and-function-among-women-with-chronic-pelvic-musculoskeletal-pain
#1
Joshua A Rash, Kirsti Toivonen, Magali Robert, Maryam Nasr-Esfahani, John F Jarrell, Tavis S Campbell
INTRODUCTION: This protocol presents the rationale and design for a trial evaluating the efficacy of intranasal oxytocin in improving pain and function among women with chronic pelvic musculoskeletal pain. Oxytocin is a neuropeptide traditionally recognised for involvement in labour, delivery and lactation. Novel evidence suggests that oxytocin decreases pain sensitivity in humans. While oxytocin administration has been reported to lower pain sensitivity among patients experiencing chronic back pain, headache, constipation and colon pain, no research has evaluated the association between intranasal oxytocin and chronic pelvic musculoskeletal pain...
April 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28400416/top-medical-centers-sign-on-to-single-irb-model
#2
(no author information available yet)
All 64 member institutions of the NIH's Clinical and Translational Science Awards program have agreed to a common framework for running multisite trials under the umbrella of just one Institutional Review Board. The NCI has long offered a centralized review board option. Come September, single Institutional Review Boards will be mandatory for all NIH-backed studies.
April 11, 2017: Cancer Discovery
https://www.readbyqxmd.com/read/28390878/protective-effects-of-different-exercise-modalities-in-an-alzheimer-s-disease-like-model
#3
Dilek Özbeyli, Gülce Sarı, Naziye Özkan, Betül Karademir, Meral Yüksel, Özlem Tuğçe Çilingir Kaya, Özgür Kasımay Çakır
Our aim was to investigate the probable protective effects of aerobic, resistance and combined exercise methods on ovariectomy and d-galactose induced Alzheimer's Disease (AD)-like model. d-galactose (100mg/kg) or saline were administered intraperitoneally for 6 weeks to ovariectomized or sham-operated rats (n=8/group). Aerobic (AE), resistance (RE) and combined exercises (CE) (aerobic+resistance) were performed for 3 times a week for 6 weeks. Anxiety level and cognitive functions were evaluated via hole-board and object recognition tests...
April 5, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28374195/pathbot-a-radiology-pathology-correlation-dashboard
#4
Linda C Kelahan, Amit D Kalaria, Ross W Filice
Pathology is considered the "gold standard" of diagnostic medicine. The importance of radiology-pathology correlation is seen in interdepartmental patient conferences such as "tumor boards" and by the tradition of radiology resident immersion in a radiologic-pathology course at the American Institute of Radiologic Pathology. In practice, consistent pathology follow-up can be difficult due to time constraints and cumbersome electronic medical records. We present a radiology-pathology correlation dashboard that presents radiologists with pathology reports matched to their dictations, for both diagnostic imaging and image-guided procedures...
April 3, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28373333/small-decline-in-low-value-back-imaging-associated-with-the-choosing-wisely-campaign-2012-14
#5
Arthur S Hong, Dennis Ross-Degnan, Fang Zhang, J Frank Wharam
Choosing Wisely was launched by the American Board of Internal Medicine in April 2012 as a patient- and clinician-targeted campaign to reduce potentially unnecessary "low-value" medical services. The campaign's impact on low- and high-value care beyond its first year is unknown; furthermore, it is unknown whether some patients such as members of consumer-directed health plans and people residing in different US regions have responded more than others. To evaluate the impact of Choosing Wisely, we used commercial insurance claims to track changes in the use of low-value imaging (x-ray, computed tomography, and magnetic resonance imaging) for back pain before and after the campaign began, a period running from 2010 to 2014...
April 1, 2017: Health Affairs
https://www.readbyqxmd.com/read/28339444/a-review-of-long-term-pain-relief-after-genicular-nerve-radiofrequency-ablation-in-chronic-knee-osteoarthritis
#6
Ferdinand Iannaccone, Samuel Dixon, Andrew Kaufman
BACKGROUND: Studies of radiofrequency ablation (RFA) of genicular nerves have reportedly significantly decreased pain up to 3 months post ablation, but no longer term effects have been reported. We performed an analysis of long-term pain relief of 31 RFA procedures of the genicular nerves to analyze the degree of pain relief past 3 months, culminating at 6 months. STUDY DESIGN: Chart review and study design was approved by Newark Health Sciences Institutional Review Board (IRB)...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28320980/effects-of-intervention-program-for-systematic-use-of-transfer-equipment-on-care-workers-low-back-pain-in-elderly-care-facilities
#7
Kazuyuki Iwakiri, Ko Matsudaira, Kiyosi Ichikawa, Masaya Takahashi
OBJECTIVE: The purpose of this study was to investigate the effects of an intervention program to prevent care workers' low back pain by the systematic use of transfer equipment at elderly care facilities. METHODS: Questionnaire surveys were administered to administrators and care workers before (baseline), 1 year after, and 2.5 year after starting the program at two elderly care facilities. Care workers at the intervention facility were requested to ensure the use of a transfer's hoist, sliding board, and sliding sheet when assisting in the transfer of residents who were judged as appropriate to use the equipment (27...
March 17, 2017: Sangyō Eiseigaku Zasshi, Journal of Occupational Health
https://www.readbyqxmd.com/read/28257381/effect-of-sleep-position-on-the-ocular-surface
#8
David Alevi, Henry D Perry, Alexander Wedel, Eric Rosenberg, Limor Alevi, Eric D Donnenfeld
PURPOSE: Dry eye disease is a multifactorial disease with numerous well-documented risk factors. However, to date, sleep position has not been associated with this condition. After observing patients in our practice, we believe that the sleep position in some cases may significantly affect dry eye and meibomian gland dysfunction (MGD). METHODS: This is a single-centered, cross-sectional, noninterventional, institutional review board-approved, single-masked, nonrandomized study of 100 patients whose complaints were related to dry eye disease and a control group of 25 age-matched asymptomatic patients...
May 2017: Cornea
https://www.readbyqxmd.com/read/28253044/wearing-an-inflatable-vest-alters-muscle-activation-and-trunk-angle-while-paddling-a-surfboard
#9
Jeff A Nessler, Thomas Hastings, Kevin Greer, Sean C Newcomer
Low back pain is a commonly reported problem among recreational surfers. Some individuals report that wearing a vest with an inflatable bladder that alters trunk angle may help to alleviate pain. The purpose of this study was to determine whether such a vest has an effect on muscle activation and extension of the lower back. Twelve recreational surfers completed 12 paddling trials at 1.1 m/s in a swim flume on both a shortboard and a longboard on two separate days. Three conditions of no vest, vest uninflated, and vest inflated were presented to participants in random order...
March 2, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28240140/-what-else-can-i-do-insights-from-atrial-fibrillation-patient-communication-online
#10
Kirsten Redman, Sally Thorne, Sandra B Lauck, Tarnia Taverner
BACKGROUND: Many patients with atrial fibrillation experience uncertainty and psychological distress. Internet support groups for atrial fibrillation have yet to be studied. AIM: To determine the content and dialogue on an online message board for atrial fibrillation with the purpose of elucidating information and support needs from patient perspectives. METHODS: Interpretative description methodology was undertaken to explore conversation from a publicly available website for atrial fibrillation over a 3-month period...
March 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28207655/internally-randomized-control-trial-of-radiation-exposure-using-ultra-low-radiation-imaging-versus-traditional-c-arm-fluoroscopy-for-patients-undergoing-single-level-minimally-invasive-transforaminal-lumbar-interbody-fusion
#11
Timothy Y Wang, S Harrison Farber, Scott S Perkins, Adam G Back, Sarah A Byrd, Debbie Chi, David Vincent, Isaac O Karikari
STUDY DESIGN: Randomized controlled trial. OBJECTIVE: To compare radiation exposure between ultra-low radiation imaging (ULRI) with image enhancement and standard-dose fluoroscopy for patients undergoing minimally invasive transforaminal lumbar interbody fusion (MIS TLIF). SUMMARY OF BACKGROUND DATA: Although the benefits of MIS are lauded by many, there is a significant amount of radiation exposure to surgeon and operating room personnel...
February 15, 2017: Spine
https://www.readbyqxmd.com/read/28184098/full-scale-experimental-investigation-to-quantify-building-component-ignition-vulnerability-from-mulch-beds-attacked-by-firebrand-showers
#12
Samuel L Manzello, Sayaka Suzuki, Daisaku Nii
Structure ignition by wind-driven firebrand showers is an important fire spread mechanism in large outdoor fires. Experiments were conducted with three common mulch types (shredded hardwood mulch, Japanese Cypress wood chips, and pine bark nuggets) placed adjacent to realistic-scale reentrant corners. In the first series of experiments, mulch beds were placed adjacent to a re-entrant corner constructed with wood studs and lined with oriented strand board (OSB) as the sheathing. The premise behind conducting experiments with no siding treatments applied was predicated on the notion that bare OSB mulch contact would be a worst-case scenario, and therefore, a wall assembly in the most vulnerable state to mulch ignition...
March 2017: Fire Technology
https://www.readbyqxmd.com/read/28170300/effect-of-radiation-dose-reduction-and-reconstruction-algorithm-on-image-noise-contrast-resolution-and-detectability-of-subtle-hypoattenuating-liver-lesions-at-multidetector-ct-filtered-back-projection-versus-a-commercial-model-based-iterative-reconstruction
#13
Justin Solomon, Daniele Marin, Kingshuk Roy Choudhury, Bhavik Patel, Ehsan Samei
Purpose To determine the effect of radiation dose and iterative reconstruction (IR) on noise, contrast, resolution, and observer-based detectability of subtle hypoattenuating liver lesions and to estimate the dose reduction potential of the IR algorithm in question. Materials and Methods This prospective, single-center, HIPAA-compliant study was approved by the institutional review board. A dual-source computed tomography (CT) system was used to reconstruct CT projection data from 21 patients into six radiation dose levels (12...
February 7, 2017: Radiology
https://www.readbyqxmd.com/read/28160011/translation-and-linguistic-validation-of-the-persian-version-of-the-bristol-female-lower-urinary-tract-symptoms-instrument
#14
Abbas Ali Pourmomeny, Zahra Sadat Rezaeian, Mahsa Soltanmohamadi
INTRODUCTION AND HYPOTHESIS: The aim of this study was to evaluate the psychometric properties of the Persian version of the International Consultation on Incontinence Modular Questionnaire for Female Lower Urinary Tract Symptoms (ICIQ-FLUTS) in patients with urinary tract dysfunction. METHODS: After gaining permission from the International Consultation on Incontinence Modular Questionnaire (ICIQ) advisory board, the English Female Lower Urinary Tract Symptoms (FLUTS) questionnaire was translated into Persian and then translated back into English...
February 3, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28158163/prevalence-of-specific-types-of-pain-diagnoses-in-a-sample-of-united-states-adults
#15
Kelly Ryan Murphy, Jing L Han, Siyun Yang, Syed Mohammed Qasim Hussaini, Aladine A Elsamadicy, Beth Parente, Jichun Xie, Promila Pagadala, Shivanand P Lad
BACKGROUND: Patients with pain conditions place significant demands on health care services globally. Health economists have reported the annual economic cost of pain in the United States as high as $635 billion. A common challenge in treating patients suffering from chronic pain conditions is accurate diagnosis and treatment. OBJECTIVE: The aim of this study was to determine the modern-day prevalence of individual types of pain diagnoses in adults. STUDY DESIGN: Retrospective analysis of Truven MarketScan® Commercial and Medicare Supplemental database...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28158159/full-endoscopic-assisted-lumbar-decompressive-surgery-performed-in-an-outpatient-ambulatory-facility-report-of-5-years-of-complications-and-risk-factors
#16
Solomon Kamson, Andrea M Trescot, Paul D Sampson, Yiyi Zhang
BACKGROUND: Minimally invasive surgery (MIS) technique is becoming the standard tissue sparing approach for decompression of lumbar central and lateral recess stenosis, intervertebral disc herniation, or any situation that would have required extensive open decompression laminectomy. Full-endoscopic or arthroscopic assisted surgery is arguably the "ultra-MIS" approach to lumbar spinal pathology. Age and body mass index (BMI) are significant risk factors to be considered in full-endoscopic assisted ultra-MIS...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28103119/iatrogenic-spinal-cord-injury-in-a-trauma-patient-with-ankylosing-spondylitis
#17
Ahmad Maarouf, Colleen M McQuown, Jennifer A Frey, Rami A Ahmed, Lisa Derrick
BACKGROUND: The recommended practice for over 30 years has been to routinely immobilize patients with unstable cervical spinal injuries using cervical spinal collars. It is shown that patients with Ankylosing spondylitis (AS) are four times more likely to suffer a spinal fracture compared to the general population and have an eleven-fold greater risk of spinal cord injury. Current protocols of spinal immobilization were responsible for secondary neurologic deterioration in some of these patients...
January 19, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28070991/a-new-chemmedchem-era
#18
EDITORIAL
David Peralta, Scott D Williams
Moving in medchem: Editors David Peralta and Scott Williams look back at the ChemMedChem 10(th) anniversary celebration in 2016 and introduce exciting developments for the journal in 2017, including the expansion of its scope to nanomedicine, the introduction of Patent Reviews, the addition of new board members, and the publication of special issues related to the expanded scope.
January 5, 2017: ChemMedChem
https://www.readbyqxmd.com/read/28047442/su-f-t-92-clinical-benefit-for-breast-and-chest-wall-setup-in-using-a-breast-board
#19
S Li, C Miyamoto, D Serratore, Q Liang, E Dziemianowicz
PURPOSE: To validate benefit of using a breast board (BB) by analyzing the geometry and dosimetry changes of the regions of interest (ROIs) between CT scans with and without BB. METHODS: Seven patients, two chest walls (CW) and five breasts, use BB at CT simulation and no BB at diagnostic CT were included. By using deformable image registration software (Velocity AI), diagnostic CT and planning CT were rigidly co-registered according to the thoracic cage at the target...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28031978/translational-research-needs-us-to-go-back-to-basics-and-collaborate-interview-with-lars-sundstrom
#20
Lars Sundstrom
Lars Sundstrom is Director of Enterprise and Translation at the West of England Academic Health Sciences Network [1] (UK), a Professor of Practice in Translational Medicine and Co-Director of the Elizabeth Blackwell Institute for Health Research at Bristol University [2] (UK), and an honorary Professor of Medicine at Cardiff University (UK). He has extensive experience in translational medicine and clinical neurosciences, holding positions at several eminent universities. He has also held executive and board-level positions at several SMEs, developing new therapeutics for neurological conditions and tools for drug discovery...
September 2016: Future Science OA
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