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Low level laser therapy

A Ritchie, J M Kramer
Burning mouth syndrome (BMS) is a debilitating condition that has a striking female predilection. Although the oral mucosa is normal in appearance, patients with BMS experience oral burning that most commonly localizes to the lips and tongue. BMS is a diagnosis of exclusion, and all underlying pathoses associated with allodynia must be ruled out prior to rendering the diagnosis. The etiopathogenesis of BMS remains poorly understood, and thus patient management is challenging. Data indicate that oral and systemic factors both contribute to the development and persistence of the condition...
June 1, 2018: Journal of Dental Research
Luciana Gonçalves Langella, Heliodora Leão Casalechi, Shaiane Silva Tomazoni, Douglas Scott Johnson, Regiane Albertini, Rodney Capp Pallotta, Rodrigo Labat Marcos, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior
When conservative treatments fail, hip osteoarthritis (OA), a chronic degenerative disease characterized by cartilage wear, progressive joint deformity, and loss of function, can result in the need for a total hip arthroplasty (THA). Surgical procedures induced tissue trauma and incite an immune response. Photobiomodulation therapy (PBMt) using low-level laser therapy (LLLT) and/or light-emitting diode therapy (LEDT) has proven effective in tissue repair by modulating the inflammatory process and promoting pain relief...
June 16, 2018: Lasers in Medical Science
Sehnaz Tezcan, Funda Ulu Ozturk, Nihal Uslu, Merve Nalbant, Oya Umit Yemisci
OBJECTIVES: To evaluate the efficacy of low-level laser therapy on median nerve stiffness by using strain elastography in carpal tunnel syndrome (CTS). METHODS: This study included 37 wrists of 34 patients with mild or moderate CTS between January 2016 and August 2016. The control group comprised 17 patients (18 wrists) with CTS who were treated with wrist splinting for 3 weeks. The low-level laser therapy group included 17 patients (19 wrists) with CTS who were treated with a combination of splinting and low-level laser therapy, which was applied 5 times per week for 3 weeks...
June 11, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Marcelie Priscila de Oliveira Rosso, Daniela Vieira Buchaim, Natália Kawano, Gabriela Furlanette, Karina Torres Pomini, Rogério Leone Buchaim
Photobiomodulation therapy (PBMT) has been investigated because of its intimate relationship with tissue recovery processes, such as on peripheral nerve damage. Based on the wide range of benefits that the PBMT has shown and its clinical relevance, the aim of this research was to carry out a systematic review of the last 10 years, ascertaining the influence of the PBMT in the regeneration of injured peripheral nerves. The search was performed in the PubMed/MEDLINE database with the combination of the keywords: low-level laser therapy AND nerve regeneration...
June 9, 2018: Bioengineering
I R Karaca, G Ergun, D N Ozturk
Purpose: The purpose of this study was to investigate the effects of biostimulation lasers and ozone therapy on osseointegration of immediately loaded implants. Materials and Methods: A total number of 100 implants (DTI Implant Systems) were applied to 25 patients evenly. Temporary crowns were applied to each patient on the same session as the surgery. Implants were divided into four treatment groups (Group 1: low-level laser therapy (LLLT) group, Group 2: ozone therapy group, Group 3: different protocol of ozone therapy group, and Group 4: control group) each with 25 implants...
June 2018: Nigerian Journal of Clinical Practice
Gokhan Gurler, Bahar Gursoy
PURPOSE: The purpose of the study was to investigate the histopathological effects of low level laser therapy (LLLT) application in distraction osteogenesis (DO). MATERIALS AND METHODS: Twenty adult female New Zealand white rabbits were included in the study. Under general anesthesia unilateral mandibular corpus osteotomy was performed. Custom made external distractors were placed to right mandibles of rabbits. After five days of latency period, distractors were activated once a day for 5 days with 1mm/day frequency...
June 6, 2018: Journal of Stomatology, Oral and Maxillofacial Surgery
Joelita de Alencar Fonseca Santos, Mariana Barbosa Dias Campelo, Rauirys Alencar de Oliveira, Renata Amadei Nicolau, Verônica Elis Araújo Rezende, Emilia Ângela Loschiavo Arisawa
OBJECTIVE: To analyze the efficacy of the therapeutic use of Low-Level Laser Therapy (LLLT) on the tissue repair process of chronic wounds in patients with diabetic feet through the analysis of Pressure Ulcer Scale for Healing (PUSH) scales, pain and the measurement done using the ImageJ© software. METHODS: This clinical trial was carried out with 18 patients 30-59 years of age, who had chronic wounds on their foot due to complications of diabetes mellitus. The patients were randomly allocated in two different groups of equal numbers: Control and Laser Groups...
June 2018: Photomedicine and Laser Surgery
Michael R Hamblin, Ying-Ying Huang, Vladimir Heiskanen
Photobiomodulation (PBM), also known as low-level laser (light) therapy, was discovered over 50 years ago, but only recently has it been making progress towards wide acceptance. PBM originally used red and near-infrared (NIR) lasers, but now other wavelengths and non-coherent light emitting diodes (LEDs) are being explored. The almost complete lack of side-effects makes the conduction of controlled clinical trials relatively easy. Laboratory research has mainly concentrated on mammalian cells (normal or cancer) in culture, and small rodents (mice and rats) as models of different diseases...
June 8, 2018: Photochemistry and Photobiology
Jeffy Ann Jose, Sanju Somaiah, Sunil Muddaiah, Balakrishna Shetty, Goutham Reddy, S Roopa
Background and Objectives: Orthodontic forces are known to produce mechanical damage and inflammatory mediators such as prostaglandins (PGs) and interleukin (IL)-1, in the periodontium and dental pulp. Low-level laser therapy (LLLT) is a stimulator of the on-going biological process in tissue and found to be effective in modulating cell activity, which is involved in orthodontic tooth movement. Here, a humble effort has been made to study two such cytokines, namely IL-1 β and PG E2 (PGE2) which are partially responsible for bone turnover...
April 2018: Contemporary Clinical Dentistry
Saran Arumughan, Sanju Somaiah, Sunil Muddaiah, Balakrishna Shetty, Goutham Reddy, S Roopa
Background and Objectives: A major concern of orthodontic patients is treatment time. Reducing the treatment time requires increasing the rate of orthodontic tooth movement. Research has proved that bone resorption is the rate-limiting step in tooth movement. Therefore, any procedure that potentiates osteoclastic activity is capable of increasing the rate of orthodontic tooth movement. Low-level laser has been indicated to have the capability to facilitate the differentiation of the osteoclastic and osteoblastic cells, which are responsible for the bone remodeling process...
April 2018: Contemporary Clinical Dentistry
Ahmed Mohamed Abohabib, Mona Mohamed Fayed, Amr H Labib
OBJECTIVE: To investigate the effect of low-intensity laser therapy on mini-implant stability using resonance frequency analysis during canine retraction with fixed appliances. DESIGN: A split-mouth randomised clinical trial. SETTING: Subjects were recruited and treated in the outpatient clinic, Department of Orthodontics, Faculty of Dentistry, Cairo University. PARTICIPANTS: Fifteen subjects with mean age 20.9 (±3...
June 6, 2018: Journal of Orthodontics
M Hughes, T Moore, J Manning, J Wilkinson, S Watson, P Samraj, G Dinsdale, C Roberts, L E Rhodes, A L Herrick, A Murray
BACKGROUND: Locally acting, well-tolerated treatments for systemic sclerosis (SSc) digital ulcers (DUs) are needed. OBJECTIVES: Our primary aim was to investigate the safety, feasibility and tolerability of a novel low level light therapy (LTTT). A secondary aim was to tentatively assess efficacy. METHODS: A custom-built device comprising infrared (850nm), red (660nm) and violet (405nm) LEDs was utilised. DUs were irradiated with 10J/cm2 twice weekly for three weeks, with follow-up at weeks 4&8...
June 4, 2018: Journal of Dermatological Treatment
Gang-Zhu Xu, Jie Jia, Lin Jin, Jia-Heng Li, Zhan-Yue Wang, Dong-Yuan Cao
Objectives: We systematically reviewed randomized controlled trials (RCTs) of the effect of low-level laser therapy (LLLT) versus placebo in patients with temporomandibular disorder (TMD). Methods: A systematic search of multiple online sources electronic databases was undertaken. The methodological quality of each included study was assessed using the modified Jadad scale, and the quality of evidence was evaluated using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system...
2018: Pain Research & Management: the Journal of the Canadian Pain Society
George David Baxter, Lizhou Liu, Steve Tumilty, Simone Petrich, Cathy Chapple, Juanita J Anders
OBJECTIVES: This study aimed to determine the feasibility of conducting a full scale randomized controlled trial investigating the effectiveness of low level laser therapy (LLLT), also known as photobiomodulation (PBM) therapy, used in addition to conventional therapy, for managing breast cancer related lymphedema (BCRL). MATERIALS AND METHODS: Patients with BCRL were recruited from the Southern District Health Board (New Zealand) via lymphedema therapists' referrals, and randomly allocated into either the laser group, which received BCRL conventional therapy (e...
May 30, 2018: Lasers in Surgery and Medicine
Han Wang, Yi Liu, Zhaohui Wang, Man Yang, Yueqing Gu
NO (nitric oxide) has dual functions in cancer, promoting carcinogenesis in low concentrations and inducing tumor cell apoptosis at high concentrations. The dual-edged-sword functions of NO make it particularly appealing to develop a sensitive and specific chemical probe for its detection. However, most NO sensors suffer from poor Stokes shifts and are limited by ultraviolet (UV) or visible light excitation, which render it difficult to avoid the intrinsic background signal. In this study, an 808 nm laser-excited Nd3+-sensitized upconversion nanoprobe based on LRET (luminescence resonance energy-transfer) for NO detection was constructed for the first time...
May 30, 2018: Nanoscale
Amin Davoudi, Behnaz Ebadian, Saeid Nosouhian
STATEMENT OF PROBLEM: Denture stomatitis (DS) is an inflammatory oral lesion that occurs mostly in elderly denture wearers and that can negatively affect their quality of life. The conventional treatment plan for DS is topical or systemic fungicidal drug therapy, which are not without side effects. PURPOSE: The purpose of this systematic review was to evaluate the clinical outcomes of using low-level laser therapy (LLLT) or photodynamic therapy (PDT) in the treatment of DS by reviewing high-quality published articles...
May 25, 2018: Journal of Prosthetic Dentistry
Sergey Vladimirovich Moskvin, Oleg Ivanovich Apolikhin
In half of the cases, the infertility of the couple is due to the disorder of the male fertility. The leading factors that cause male infertility are urogenital infections, disorders of the immune system, testicular and prostate pathology, as well as endocrine disorders. Low level laser therapy (LLLT) is a very effective physical therapy method, used in many areas of medicine, including obstetrics and gynaecology, andrology and urology; and it is recommended as an integral part of the complex treatment of infertility...
June 2018: BioMedicine
Erkan Çırak, Anıl Özyurt, Tuncay Peker, Suna Ömeroğlu, Mehmet Nadir Güngör
PURPOSE: The aim of this study was to evaluate the effects of helium-neon and gallium-aluminum-arsenide lasers with various doses on bone healing following tooth extraction. MATERIALS AND METHODS: Maxillary right incisor teeth of 30 female albino Wistar rats were extracted. Five groups were established: four groups treated with helium-neon or gallium-aluminum-arsenide lasers and a control group. Both laser groups' rats received energy doses of 6 J/cm2 and 10 J/cm2 for 7 days...
May 10, 2018: Journal of Cranio-maxillo-facial Surgery
Sadeq Ali Al-Maweri, Butchibabu Kalakonda, Nader Ahmed AlAizari, Walid A Al-Soneidar, Sajna Ashraf, Saleem Abdulrab, Eman Saleh Al-Mawri
Recurrent herpes labialis (RHL) is a highly prevalent viral infection that affects the oro-facial region. Current treatment options have limited efficacy in reducing healing time and recurrence rate of the disease. Recently, low-level laser therapy has been proposed as a potential treatment alternative for the management of RHL with no side effects. This systematic review aims to evaluate the effectiveness of laser therapy in the management and prevention of RHL. A comprehensive search of Medline/PubMed, Scopus, and Web of Science was carried out to identify published clinical trials comparing laser intervention to active and/or non-active controls for the treatment of RHL...
May 25, 2018: Lasers in Medical Science
Aditya K Gupta, Rachel R Mays, Michelle S Dotzert, Sarah G Versteeg, Neil H Shear, Vincent Piguet
Androgenetic alopecia, or male/female pattern baldness, is the most common type of progressive hair loss disorder. The aim of this paper is to review recent advances in non-surgical treatments for androgenetic alopecia and identify the most effective treatments. A network meta-analysis (NMA) was conducted of the available literature of the six most common non-surgical treatment options for treating androgenetic alopecia in both men and women; dutasteride 0.5mg, finasteride 1mg, low level laser therapy (LLLT), minoxidil 2%, minoxidil 5% and platelet rich plasma (PRP)...
May 24, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
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