keyword
https://read.qxmd.com/read/38504228/ischemic-heart-disease-related-mortality-in-brazil-2006-to-2020-a-study-of-multiple-causes-of-death
#1
JOURNAL ARTICLE
Luiz A V M Bastos, Paolo B Villela, Jose L P Bichara, Emilia M do Nascimento, Eduardo L V M Bastos, Basilio de B Pereira, Glaucia M M Oliveira
CONTEXT: Both the aging of the population and the increase in noncommunicable diseases may influence the progression and outcomes culminating in death, changing the evolution of ischemic heart diseases (IHDs) and their associated causes. Using the multiple causes of death method could help understand the magnitude of these relationships and enable better targeting of investments in health. OBJECTIVES: To evaluate the mortality from IHD in Brazil between 2006 and 2020 using the method of multiple causes and identify differences in the distribution pattern of IHD mortality by sex and geographic region...
March 19, 2024: BMC Public Health
https://read.qxmd.com/read/38477023/travel-distance-and-outcomes-after-surgical-aortic-valve-among-veterans
#2
JOURNAL ARTICLE
Brendin R Beaulieu-Jones, Noah Siegel, Loreski Collado, Hillary J Mull, Jacquelyn A Quin
OBJECTIVE: To investigate the association between travel distance and postoperative length of stay (LOS) and discharge disposition among veterans undergoing surgical aortic valve replacement (SAVR). DATA SOURCES/STUDY SETTING: We performed a retrospective cohort study of patients undergoing SAVR, with or without coronary artery bypass grafting (CABG) at VA Boston Healthcare (January 1, 2005-December 31, 2015). STUDY DESIGN: Postoperative LOS and discharge disposition were compared for SAVR patients based on travel distance to the facility: <100 miles or ≥100 miles...
March 13, 2024: Health Services Research
https://read.qxmd.com/read/38450367/inflammation-as-the-nexus-exploring-the-link-between-acute-myocardial-infarction-and-chronic-obstructive-pulmonary-disease
#3
REVIEW
Eloise Marriott, Aran Singanayagam, Juma El-Awaisi
Chronic obstructive pulmonary disease (COPD), particularly following acute exacerbations (AE-COPD), significantly heightens the risks and mortality associated with acute myocardial infarction (AMI). The intersection of COPD and AMI is characterised by a considerable overlap in inflammatory mechanisms, which play a crucial role in the development of both conditions. Although extensive research has been conducted on individual inflammatory pathways in AMI and COPD, the understanding of thrombo-inflammatory crosstalk in comorbid settings remains limited...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38419108/implementation-of-early-prophylaxis-for-deep-vein-thrombosis-in-intracerebral-hemorrhage-patients-an-observational-study-from-the-chinese-stroke-center-alliance
#4
JOURNAL ARTICLE
Ran Zhang, Weige Sun, Yana Xing, Yongjun Wang, Zixiao Li, Liping Liu, Hongqiu Gu, Kaixuan Yang, Xin Yang, Chunjuan Wang, Qingbo Liu, Qian Xiao, Weixin Cai
BACKGROUND: There is substantial evidence to support the use of several methods for preventing deep-vein thrombosis (DVT) following intracerebral hemorrhage (ICH). However, the extent to which these measures are implemented in clinical practice and the factors influencing patients' receipt of preventive measures remain unclear. Therefore, we aimed to evaluate the rate of the early implementation of DVT prophylaxis and the factors associated with its success in patients with ICH. METHODS: This study enrolled 49,950 patients with spontaneous ICH from the Chinese Stroke Center Alliance (CSCA) between August 2015 and July 2019...
February 28, 2024: Thrombosis Journal
https://read.qxmd.com/read/38404733/clinical-features-of-extrahepatic-portal-vein-obstruction-myeloproliferative-neoplasms-eliminate-hypersplenic-hematologic-changes-in-extrahepatic-portal-vein-obstruction
#5
JOURNAL ARTICLE
Tetsuya Shimizu, Hiroshi Yoshida, Nobuhiko Taniai, Masato Yoshioka, Yoichi Kawano, Akira Matsushita, Junji Ueda, Takuma Iwai, Takahiro Murokawa, Takashi Ono, Akira Hamaguchi
Extrahepatic portal vein obstruction (EHPVO) is a rare disease. Most EHPVO patients are usually referred to a gastroenterologist for intestinal bleeding and hypersplenic thrombocytopenia; however, hypercoagulative diseases may be occult in these patients and require anticoagulation. The purpose of this study was to elucidate the clinical characteristics of EHPVO. We conducted a retrospective analysis of the hospital database, evaluating the medical records of 15 patients (7 males, 8 females, mean age of onset 42...
February 2024: Intractable & Rare Diseases Research
https://read.qxmd.com/read/38404616/association-between-myocardial-infarction-and-triglyceride-glucose-index-a-study-based-on-nhanes-database
#6
JOURNAL ARTICLE
Dandan Zheng, Ligong Cao
OBJECTIVE: To investigate differences in levels of the triglyceride-glucose (TyG) index between individuals with myocardial infarction (MI) and those without MI, as well as the association between TyG index and risk of MI. METHODS: Data from the National Health and Nutrition Examination Survey (NHANES) for US adults from 2013 to 2018 were included in this study. Using MI as an outcome variable and TyG index as an exposure variable, logistic regression models were employed to analyze relationship between MI and TyG index...
2024: Global Heart
https://read.qxmd.com/read/38394543/explainable-artificial-intelligence-for-predicting-red-blood-cell-transfusion-in-geriatric-patients-undergoing-hip-arthroplasty-machine-learning-analysis-using-national-health-insurance-data
#7
JOURNAL ARTICLE
Hyunyoung Seong, Kwang-Sig Lee, Yumin Choi, Donghyun Na, Jaewoo Kim, Hyeon Ju Shin, Ki Hoon Ahn
This study uses machine learning and population data to analyze major determinants of blood transfusion among patients with hip arthroplasty. Retrospective cohort data came from Korea National Health Insurance Service claims data for 19,110 patients aged 65 years or more with hip arthroplasty in 2019. The dependent variable was blood transfusion (yes vs no) in 2019 and its 31 predictors were included. Random forest variable importance and Shapley Additive Explanations were used for identifying major predictors and the directions of their associations with blood transfusion...
February 23, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38391807/impact-of-the-italian-healthcare-outcomes-program-pne-on-the-care-quality-of-the-poorest-performing-hospitals
#8
JOURNAL ARTICLE
Matteo Fiore, Alessandro Bianconi, Cecilia Acuti Martellucci, Annalisa Rosso, Enrico Zauli, Maria Elena Flacco, Lamberto Manzoli
One of the main aims of the Italian National Healthcare Outcomes Program (Programma Nazionale Esiti, PNE) is the identification of the hospitals with the lowest performance, leading them to improve their quality. In order to evaluate PNE impact for a subset of outcome indicators, we evaluated whether the performance of the hospitals with the lowest scores in 2016 had significantly improved after five years. The eight indicators measured the risk-adjusted likelihood of the death of each patient (adjusted relative risk-RR) 30 days after the admission for acute myocardial infarction, congestive heart failure, stroke, chronic obstructive pulmonary disease, chronic kidney disease, femur fracture or lung and colon cancer...
February 7, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38364198/ambient-temperature-and-risk-of-cardiovascular-and-respiratory-adverse-health-outcomes-a-nationwide-cross-sectional-study-from-spain
#9
JOURNAL ARTICLE
Hicham Achebak, Grégoire Rey, Simon J Lloyd, Marcos Quijal-Zamorano, Raúl Fernando Méndez-Turrubiates, Joan Ballester
AIMS: We assessed the association of temperature and temperature variability with cause-specific emergency hospitalizations and mortality from cardiovascular and respiratory diseases in Spain, as well as the effect modification of this association by individual and contextual factors. METHODS AND RESULTS: We collected data on health (hospital admissions and mortality), weather (temperature and relative humidity), and relevant contextual indicators for 48 Spanish provinces during 2004-2019...
February 13, 2024: European Journal of Preventive Cardiology
https://read.qxmd.com/read/38317148/non-covid-19-hospitalization-and-mortality-during-the-covid-19-pandemic-in-iran-a-longitudinal-assessment-of-41-million-people-in-2019-2022
#10
JOURNAL ARTICLE
Mahya Razimoghadam, Mehdi Yaseri, Mehdi Rezaee, Aliakbar Fazaeli, Rajabali Daroudi
BACKGROUND: During a COVID-19 pandemic, it is imperative to investigate the outcomes of all non-COVID-19 diseases. This study determines hospital admissions and mortality rates related to non-COVID-19 diseases during the COVID-19 pandemic among 41 million Iranians. METHOD: This nationwide retrospective study used data from the Iran Health Insurance Organization. From September 23, 2019, to Feb 19, 2022, there were four study periods: pre-pandemic (Sept 23-Feb 19, 2020), first peak (Mar 20-Apr 19, 2020), first year (Feb 20, 2020-Feb 18, 2021), and the second year (Feb 19, 2021-Feb 19, 2022) following the pandemic...
February 5, 2024: BMC Public Health
https://read.qxmd.com/read/38316592/snoring-survivors-the-impact-of-obstructive-sleep-apnoea-and-continuous-positive-airway-pressure-use-on-in-hospital-mortality-length-of-stay-and-costs-among-patients-hospitalised-with-acute-cardiovascular-disease-a-retrospective-analysis-of-2016-2019-national
#11
JOURNAL ARTICLE
Ikechukwu Ogbu, Bagrat Hakobyan, Christoph Sossou, Jeffrey Levisman, Chukwudi Obiagwu, Alfred Danielian
BACKGROUND: The routine administration of supplemental oxygen to non-hypoxic patients with acute myocardial infarction (AMI) has been abandoned for lack of mortality benefit. However, the benefits of continuous positive airway pressure (CPAP) use in patients hospitalised with acute cardiovascular disease and concomitant obstructive sleep apnoea (OSA) remain to be elucidated. METHODS: In this retrospective case-control analysis, using 10th International Classification of Diseases, Clinical Modification (ICD-10) codes, we searched the 2016-2019 Nationwide Inpatient Sample for patients diagnosed with unstable angina (UA), AMI, acute decompensated heart failure (ADHF) and atrial fibrillation with rapid ventricular response (AFRVR), who also carried a diagnosis of OSA...
February 5, 2024: BMJ Open
https://read.qxmd.com/read/38309959/-standard-technical-specifications-for-methacholine-chloride-methacholine-bronchial-challenge-test-2023
#12
JOURNAL ARTICLE
(no author information available yet)
The methacholine challenge test (MCT) is a standard evaluation method of assessing airway hyperresponsiveness (AHR) and its severity, and has significant clinical value in the diagnosis and treatment of bronchial asthma. A consensus working group consisting of experts from the Pulmonary Function and Clinical Respiratory Physiology Committee of the Chinese Association of Chest Physicians, the Task Force for Pulmonary Function of the Chinese Thoracic Society, and the Pulmonary Function Group of Respiratory Branch of the Chinese Geriatric Society jointly developed this consensus...
February 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/38304360/chronic-multimorbidity-of-low-back-pain-or-other-chronic-back-disorders-in-the-republic-of-croatia
#13
JOURNAL ARTICLE
Jelena Marunica Karšaj, Tomislav Benjak, Larisa Stojanović, Frane Grubišić, Diana Balen, Simeon Grazio
The aim was to assess the prevalence of chronic multimorbidity in patients with chronic low back pain or other chronic back disorders (BD). We analyzed data from the population-based cross-sectional European Health Interview Survey (EHIS) performed in the Republic of Croatia 2014-2015 by the Croatian Institute of Public Health. Outcome was the point-prevalence of chronic multimorbidity defined as having ≥2 chronic illnesses out of 14 contained in the EHIS questionnaire, after adjustment for ten sociodemographic, anthropometric and lifestyle confounders...
April 2023: Acta Clinica Croatica
https://read.qxmd.com/read/38287280/analysis-of-the-correlation-between-serum-klotho-and-feno-a-cross-sectional-study-from-nhanes-2007-2012
#14
JOURNAL ARTICLE
Haiyan Mao, Zhenye Xie, Shanshan Huang, Xingkai Shen, Shaofeng Jin, Tong Lin, Zhouxin Yang
BACKGROUND: Klotho is an anti-aging protein that has multiple functions and may play a key role in the pathogenesis and progression of chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD). Fractional Exhaled Nitric Oxide (FeNO) is a non-invasive and novel biomarker that has the advantages of being simple, fast and reproducible. It can effectively assess the degree of airway inflammation in diseases such as asthma and COPD. Despite these insights, the relationship between serum Klotho levels and FeNO has not been explored yet...
January 29, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38266795/navigating-heart-failure-unveiling-sex-disparities-in-guideline-directed-medical-therapy-combinations
#15
JOURNAL ARTICLE
Ahmet Celik, Anil Sahin, Naim Ata, Inci Tugce Colluoglu, Dilek Ural, Emine Arzu Kanik, Mustafa Okan Ayvali, Mustafa Mahir Ulgu, Suayip Birinci, Mehmet Birhan Yilmaz
Major heart failure (HF) trials remain insufficient in terms of assessing the differences in clinical characteristics, biomarkers, treatment efficacy, and safety because of the under-representation of women. The study aimed to present sex-related disparities in HF management, including differences in demographics, co-morbidities, cardiac biomarkers, prescribed medications, and treatment outcomes. The study utilized anonymized data from the Turkish Ministry of Health's National Electronic Database between January 1, 2016, and December 31, 2022...
January 22, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38262521/associations-between-sleep-behavioral-traits-and-healthspan-a-one-sample-mendelian-randomization-study-based-on-388-909-participants-of-the-uk-biobank
#16
JOURNAL ARTICLE
Muhammed Lamin Sambou, Xiaoyu Zhao, Tongtong Hong, Nanxi Wang, Juncheng Dai
BACKGROUND: Although the association between sleep behavior and morbidity and mortality risk has been reported before, there is still uncertainty whether the observed associations are causal or confounding. Therefore, we investigated the causal relationships between sleep-behavioral traits and terminated healthspan risk using Mendelian randomization (MR). METHODS: We conducted a one-sample MR analysis to evaluate causality between six sleep-behavioral traits (sleep duration, chronotype/morningness, napping, sleeplessness/insomnia, and getting up from bed) and risk of healthspan termination among 388, 909 UK Biobank (UKB) participants...
January 21, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38249829/prevalence-of-cardiovascular-disease-and-rate-of-major-adverse-cardiovascular-events-in-severe-alpha-1-antitrypsin-deficiency-copd
#17
JOURNAL ARTICLE
Paul Ellis, Emily Bailey, Radmila Choate, Kristen E Holm, Robert A Sandhaus, Alice M Turner, Michael Newnham
AIM: Alpha-1 antitrypsin deficiency is an autosomal co-dominant condition that predisposes individuals to early-onset emphysema. As with COPD, AATD-COPD is associated with pulmonary exacerbations, which impacts on overall mortality and quality of life. Though there is evidence that COPD is associated with a higher prevalence of cardiovascular disease and major adverse cardiovascular events (MACE), it is unclear if this is true for patients with AATD-COPD. METHODS: Prevalence of cardiovascular disease was determined in two separate severe AATD cohorts: AlphaNet, USA and the Birmingham AATD registry, UK...
2024: International Journal of Chronic Obstructive Pulmonary Disease
https://read.qxmd.com/read/38199208/analyzing-the-molecular-mechanism-of-xuefuzhuyu-decoction-in-the-treatment-of-pulmonary-hypertension-with-network-pharmacology-and-bioinformatics-and-verifying-molecular-docking
#18
JOURNAL ARTICLE
Xiaoming Yu, Wenxiang Qin, Haijian Cai, Chufan Ren, Shengjing Huang, Xiao Lin, Lin Tang, Zhuohan Shan, Wail Hussein Ahmed Al-Ameer, Liangxing Wang, Hanhan Yan, Mayun Chen
BACKGROUND: XueFuZhuYu (XFZY), a typical Chinese herbal formula, has remarkable clinical effects for treating Pulmonary Hypertension (PH) with unclear mechanisms. Our research involved the utilization of network pharmacology to explore the traditional Chinese herbal monomers and their related targets within XFZY for PH treatment. Furthermore, molecular docking verification was performed. METHODS: The XFZY's primary active compounds, along with their corresponding targets, were both obtained from the TCMSP, ChEMBL, and UniProt databases...
December 30, 2023: Computers in Biology and Medicine
https://read.qxmd.com/read/38198361/the-six-pillars-of-lifestyle-medicine-in-managing-noncommunicable-diseases-the-gaps-in-current-guidelines
#19
JOURNAL ARTICLE
Rafaella Rogatto de Faria, Sergio Freitas de Siqueira, Francisco Aguerre Haddad, Gustavo Del Monte Silva, Caio Vitale Spaggiari, Martino Martinelli Filho
BACKGROUND: Noncommunicable diseases (NCDs), also known as chronic diseases that are long-lasting, are considered the major cause of death and disability worldwide, and the six pillars of lifestyle medicine (nutrition, exercise, toxic control, stress management, restorative sleep, and social connection) play an important role in a holistic management of their prevention and treatment. In addition, medical guidelines are the most accepted documents with recommendations to manage NCDs. OBJECTIVE: The present study aims to analyze the lack of lifestyle pillars concerning the major Brazilian medical guidelines for NCDs and identify evidence in the literature that could justify their inclusion in the documents...
2024: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/38196600/risk-of-atherosclerotic-cardiovascular-disease-hospitalizations-after-copd-hospitalization-among-older-adults
#20
Christopher L Mosher, Oyomoare L Osazuwa-Peters, Michael G Nanna, Neil R MacIntyre, Loretta G Que, W Schuyler Jones, Scott M Palmer, Emily C O'Brien
BACKGROUND: Meta-analyses have suggested the risk of atherosclerotic cardiovascular disease (ASCVD) events is significantly higher after a chronic obstructive pulmonary disease (COPD) exacerbation. However, these studies have been limited to highly selected patient populations potentially not generalizable to the broader population of COPD. METHODS: We assessed the risk of ASCVD hospitalizations after COPD hospitalization compared to before COPD hospitalization and identified patient factors associated with ASCVD hospitalizations after COPD hospitalization...
December 21, 2023: medRxiv
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