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https://www.readbyqxmd.com/read/28109002/value-of-ultrasonographic-features-for-assessing-malignant-potential-of-complex-cystic-breast-lesions
#1
Jin-Peng Yao, Yu-Zhi Hao, Qing Chang, Cheng-Yun Geng, Yu Chen, Wen-Peng Zhao, Yan Song, Xiang Zhou
OBJECTIVES: To assess the value of ultrasonography (US) features for determining the malignant potential of complex cystic lesions. METHODS: Seventy-nine complex cystic lesions were reviewed retrospectively. They were classified into four types according to US features in type I, the masses have a thick outer wall, thick internal septa, or both; in type II, the masses are an intracystic type with one or more discrete solid mural lesions within a cyst; in type III, the masses contain mixed cystic and solid components and are at least 50% cystic portion in a mass; in type IV, there are predominantly (at least 50%) solid masses with eccentric or central cystic foci...
January 21, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28108780/cement-augmented-screws-in-a-cervical-two-level-corpectomy-with-anterior-titanium-mesh-cage-reconstruction-a-biomechanical-study
#2
Sebastian Hartmann, Claudius Thomé, Anja Tschugg, Johannes Paesold, Pujan Kavakebi, Werner Schmölz
STUDY DESIGN: Biomechanical investigation. PURPOSE: Cervical two-level corpectomies with anterior-only instrumentation are associated with a high rate of implant-related complications. These procedures, therefore, often require an additional dorsal instrumentation to prevent screw loosening. Cement augmentation of the anterior screws in two-level corpectomies might stabilize the construct, so that a second dorsal procedure could be avoided. To evaluate the screw anchorage in cervical anterior-only procedures, an ex vivo evaluation of the range of motion (ROM) in two-level corpectomies (C4 and C5), with and without cement augmentation of the anterior screws, was carried out in this study...
January 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28108648/reduced-firing-rates-of-high-threshold-motor-units-in-response-to-eccentric-overload
#3
Tom G Balshaw, Madhu Pahar, Ross Chesham, Lewis J Macgregor, Angus M Hunter
Acute responses of motor units were investigated during submaximal voluntary isometric tasks following eccentric overload (EO) and constant load (CL) knee extension resistance exercise. Ten healthy resistance-trained participants performed four experimental test sessions separated by 5 days over a 20 day period. Two sessions involved constant load and the other two used eccentric overload. EO and CL used both sessions for different target knee eccentric extension phases; one at 2 sec and the other at 4 sec...
January 2017: Physiological Reports
https://www.readbyqxmd.com/read/28108576/dual-source-computed-tomography-based-analysis-of-stent-performance-its-association-with-valvular-calcification-and-residual-aortic-regurgitation-after-implantation-of-a-balloon-expandable-transcatheter-heart-valve
#4
Julius Gerstmeyer, Maximilian Kütting, Buntaro Fujita, Annika Schuhbäck, Martin Arnold, Jochen Börgermann, Stephan Achenbach, Ulrich Steinseifer, Jan Gummert, Stephan Ensminger
OBJECTIVES: The aim of this study was to investigate the mutual influence of valvular calcifications and transcatheter aortic valve stent geometry during and after implantation of a balloon-expandable SAPIEN(®)/SAPIEN XT(®) prostheses. Aortic valve calcification has been linked with adverse complications after transcatheter aortic valve implantation (TAVI). However, little is known about the fate of the calcifications after TAVI as well as its influence on transcatheter heart valve geometry...
January 20, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28100746/end-stopping-predicts-curvature-tuning-along-the-ventral-stream
#5
Carlos R Ponce, Till S Hartmann, Margaret S Livingstone
: Neurons in primate inferotemporal cortex (IT) are clustered into patches of shared image preferences. Functional imaging has shown that these patches are activated by natural categories (e.g., faces, body parts, and places), artificial categories (numerals, words) and geometric features (curvature and real-world size). These domains develop in the same cortical locations across monkeys and humans, which raises the possibility of common innate mechanisms. Although these commonalities could be high-level template-based categories, it is alternatively possible that the domain locations are constrained by low-level properties such as end-stopping, eccentricity, and the shape of the preferred images...
January 18, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28099241/fmri-with-central-vision-loss-effects-of-fixation-locus-and-stimulus-type
#6
Tina Plank, Jozef Frolo, Sabine Brandl-Rühle, Agnes B Renner, Herbert Jägle, Mark W Greenlee
PURPOSE: In patients with central visual field scotomata, a large part of visual cortex is not adequately stimulated. Patients often use a new eccentric fixation area on intact peripheral retina ("preferred retinal locus"-PRL) that functions as a pseudo-fovea. We used functional magnetic resonance imaging (fMRI) to examine whether stimulating this pseudo-fovea leads to increased activation or altered activation patterns in visual cortex in comparison to stimulating a comparable peripheral area in the opposite hemifield (OppPRL)...
January 18, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28098354/concealed-accessory-pathways-with-a-single-ventricular-and-two-discrete-atrial-insertion-sites
#7
Ryan T Kipp, Raed Abu Sham'a, Ito Hiroyuki, Frederick T Han, Marwan Refaat, Jonathan C Hsu, Michael E Field, Douglas E Kopp, Gregory M Marcus, Melvin M Scheinman, Kurt S Hoffmayer
BACKGROUND: Atrioventricular reciprocating tachycardia utilizing a concealed accessory pathway is common. It is well appreciated that some patients may have multiple accessory pathways with separate atrial and ventricular insertion sites. METHODS: We present three cases of AVRT utilizing concealed pathways with evidence that each utilizing a single ventricular insertion and two discrete atrial insertion sites. RESULTS: In case one, two discrete atrial insertion sites were mapped in two separate procedures, and only during the second ablation was the Kent potential identified...
January 18, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28097991/nursing-an-exquisite-obsession-clark-june-nursing-an-exquisite-obsession-220pp-%C3%A2-12-99-quay-books-9781856425094-1856425096-formula-see-text
#8
(no author information available yet)
One of the publishing trends of recent years has been nursing memoirs. Heartwarming anecdotes of the nursing care provided for eccentric patients are generally combined with attacks on supposed developments in nurse education after about 1975, and the whole account is bathed in the light of a golden age that has passed. This memoir emphatically rejects such nostalgia.
January 18, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28097654/melanopsin-expressing-ganglion-cells-in-human-retina-morphology-distribution-and-synaptic-connections
#9
Subha Nasir-Ahmad, Sammy C S Lee, Paul R Martin, Ulrike Grünert
Melanopsin-expressing retinal ganglion cells are intrinsically photosensitive cells that are involved in non-image forming visual processes such as the pupillary light reflex and circadian entrainment but also contribute to visual perception. Here we used immunohistochemistry to study the morphology, density, distribution and synaptic connectivity of melanopsin-expressing ganglion cells in four post mortem human donor retinas. Two types of melanopsin-expressing ganglion cells were distinguished based on their dendritic stratification near either the outer or the inner border of the inner plexiform layer...
January 18, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28095094/female-age-related-differences-in-biomechanics-and-muscle-activity-during-descents-on-the-outstretched-arms
#10
Lauren Jane Lattimer, Joel Lanovaz, Jon Farthing, Stéphanie Madill, Soo Kim, Stephen Robinovitch, Cathy Arnold
The purposes of this study were to examine female age differences in: 1) upper extremity (UE) and trunk muscle activity, elbow joint moment, loading force and UE energy absorption during a controlled forward body descent and 2) UE muscle strength. Twenty young (mean 24.8±3.4 yrs.) and 20 older (68.4±5.7 yrs.) women were assessed via dynamometry for isometric, concentric and eccentric UE strength and performed forward descents on force plates at three body lean angles (60, 45, and 30° from horizontal). Significant differences (p < ...
January 17, 2017: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/28092056/a-randomised-placebo-controlled-crossover-study-investigating-the-effects-of-nicotine-gum-on-strength-power-and-anaerobic-performance-in-nicotine-na%C3%A3-ve-active-males
#11
Toby Mündel, Marine Machal, Darryl J Cochrane, Matthew J Barnes
BACKGROUND: Nicotine use amongst athletes is high and increasing, especially team sports, yet the limited previous studies investigating the performance consequences of this behaviour have not examined the effects of the principal active ingredient, nicotine, per se. Therefore, we determined whether nicotine gum affected muscular and anaerobic performance. METHODS: Nine active males (24 ± 3 years) completed three trials in a random order in which 20 min prior to testing they chewed 2 mg (NIC-2), 4 mg (NIC-4) nicotine or flavour-matched placebo (PLA) gum...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28090635/sonographic-features-and-diagnosis-of-peripheral-schwannomas
#12
Fan Yang, Xian-Xiang Chen, Huo-Lin Wu, Ji-Fa Zhu, Yuan Chen, Ling-Fang Yu, Xiao-Juan Huang
BACKGROUND: To determine the sonographic features of peripheral schwannomas. METHODS: This retrospective study included 54 cases of schwannoma in 51 patients. Ultrasonography (US) and MRI were performed in all patients. The US features of each tumor were analyzed and compared with pathologic findings. The US target sign was compared with the MRI findings. RESULTS: On US, 53 of the 54 schwannomas had a regular shape and clear margins, and one had an irregular shape...
January 16, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28090602/probabilistic-tractography-for-topographically-organized-connectomes
#13
Dogu Baran Aydogan, Yonggang Shi
While tractography is widely used in brain imaging research, its quantitative validation is highly difficult. Many fiber systems, however, have well-known topographic organization which can even be quantitatively mapped such as the retinotopy of visual pathway. Motivated by this previously untapped anatomical knowledge, we develop a novel tractography method that preserves both topographic and geometric regularity of fiber systems. For topographic preservation, we propose a novel likelihood function that tests the match between parallel curves and fiber orientation distributions...
October 2016: Medical Image Computing and Computer-assisted Intervention: MICCAI ..
https://www.readbyqxmd.com/read/28089792/pharmacological-inhibition-of-pkc%C3%AE-counteracts-muscle-disease-in-a-mouse-model-of-duchenne-muscular-dystrophy
#14
V Marrocco, P Fiore, A Benedetti, S Pisu, E Rizzuto, A Musarò, L Madaro, B Lozanoska-Ochser, M Bouché
: Inflammation plays a considerable role in the progression of Duchenne Muscular Dystrophy (DMD), a severe muscle disease caused by a mutation in the dystrophin gene. We previously showed that genetic ablation of Protein Kinase C θ (PKCθ) in mdx, the mouse model of DMD, improves muscle healing and regeneration, preventing massive inflammation. To establish whether pharmacological targeting of PKCθ in DMD can be proposed as a therapeutic option, in this study we treated young mdx mice with the PKCθ inhibitor Compound 20 (C20)...
January 7, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28086951/sodium-glucose-transporter-2-sglt2-inhibition-with-empagliflozin-improves-cardiac-diastolic-function-in-a-female-rodent-model-of-diabetes
#15
Javad Habibi, Annayya R Aroor, James R Sowers, Guanghong Jia, Melvin R Hayden, Mona Garro, Brady Barron, Eric Mayoux, R Scott Rector, Adam Whaley-Connell, Vincent G DeMarco
Obese and diabetic individuals are at increased risk for impairments in diastolic relaxation and heart failure with preserved ejection fraction. The impairments in diastolic relaxation are especially pronounced in obese and diabetic women and predict future cardiovascular disease (CVD) events in this population. Recent clinical data suggest sodium glucose transporter-2 (SGLT2) inhibition reduces CVD events in diabetic individuals, but the mechanisms of this CVD protection are unknown. To determine whether targeting SGLT2 improves diastolic relaxation, we utilized empagliflozin (EMPA) in female db/db mice...
January 13, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28086799/gender-specific-association-of-decreased-estimated-glomerular-filtration-rate-and-left-vertical-geometry-in-the-general-population-from-rural-northeast-china
#16
Dongxue Dai, Ye Chang, Yintao Chen, Shasha Yu, Xiaofan Guo, Yingxian Sun
BACKGROUND: Left ventricular hypertrophy (LVH) is common and associated with cardiovascular outcomes among patients with known chronic kidney disease (CKD). However, the link between decreased estimated glomerular filtration rate (eGFR) and left ventricular (LV) geometry remains poorly explored in general population. In this study, we examined the gender-specific association between eGFR and LVH in the general population from rural Northeast China. METHODS: This survey was conducted from July 2012 to August 2013...
January 13, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28079827/differentiating-malignant-from-benign-gastric-mucosal-lesions-with-quantitative-analysis-in-dual-energy-spectral-computed-tomography-initial-experience
#17
Xiaoyan Meng, Cheng Ni, Yaqi Shen, Xuemei Hu, Xiao Chen, Zhen Li, Daoyu Hu
To investigate the value of quantitative analysis in dual energy spectral computed tomography (DESCT) for differentiating malignant gastric mucosal lesions from benign gastric mucosal lesions (including gastric inflammation [GI] and normal gastric mucosa [NGM]). This study was approved by the ethics committee, and all patients provided written informed consent. A total of 161 consecutive patients (63 with gastric cancer [GC], 48 with GI, and 50 with NGM) who underwent dual-phase contrast enhanced DESCT scans in the arterial phase (AP) and portal venous phase (PVP) were included in this study...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28079814/predictive-role-of-corneal-q-value-differences-between-nasal-temporal-and-superior-inferior-quadrants-in-orthokeratology-lens-decentration
#18
Juan Li, Cheng Yang, Wenjuan Xie, Guanrong Zhang, Xue Li, Shujun Wang, Xiaohong Yang, Jin Zeng
BACKGROUND: To investigate the association between pretreatment corneal parameters and orthokeratology lens decentration. METHODS: This retrospective study included a total of 108 eyes in 60 myopia patients, who were divided into a lens-decentration and a control group. Various pretreatment corneal parameters were analyzed by receiver operating characteristic curves (ROC curves), including corneal horizontal and vertical curvatures, diopter, corneal eccentricity (E-value), asphericity (Q-value), diameter, and astigmatism, to establish a reliable predictive model for orthokeratology lens decentration...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28078568/rediagnosing-one-of-smith-s-patients-john-mccann-with-neuromas-tumours-1849
#19
Martino Ruggieri, Andrea D Praticò, Rosario Caltabiano, Agata Polizzi
In 1849, the Irish Professor of Surgery, Sir Robert William Smith, by publishing his "Treatise on the Pathology, Diagnosis and Treatment of Neuroma", collected six previous examples of "general development of neuromatous tumours" and reported three further cases (two personal and one referred) of what is nowadays known as neurofibromatosis. Among these latter cases, there was a 35-year-old cattle-driver, John McCann, who was first admitted at hospital in 1840 because of a large tumour on the right side of his neck thought to be malignant (and a second tumour sublingually) but not operated...
January 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28074913/auditory-localisation-biases-increase-with-sensory-uncertainty
#20
Sara E Garcia, Pete R Jones, Gary S Rubin, Marko Nardini
Psychophysical studies have frequently found that adults with normal hearing exhibit systematic errors (biases) in their auditory localisation judgments. Here we tested (i) whether systematic localisation errors could reflect reliance on prior knowledge, as has been proposed for other systematic perceptual biases, and (ii) whether auditory localisation biases can be reduced following training with accurate visual feedback. Twenty-four normal hearing participants were asked to localise the position of a noise burst along the azimuth before, during, and after training with visual feedback...
January 11, 2017: Scientific Reports
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