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https://www.readbyqxmd.com/read/29346529/echocardiographic-criteria-to-detect-unicuspid-aortic-valve-morphology
#1
Sebastian Ewen, Irem Karliova, Petra Weber, Stephan H Schirmer, Hashim Abdul-Khaliq, Jakob Schöpe, Felix Mahfoud, Hans-Joachim Schäfers
Aims: Unicuspid aortic valve (UAV) is a rare congenital malformation associated with severe aortic stenosis or regurgitation. This study aimed to systematically determine echocardiographic criteria to identify UAV. Methods and results: All patients underwent a preoperative baseline examination, including echocardiography. A total of 69 patients with intraoperatively confirmed UAV underwent an aortic valve repair procedure between August 2001 and May 2011. To compare the findings of UAV cases with those of other valve morphologies, we examined 99 consecutive patients with a bicuspid aortic valve (BAV) and 103 consecutive patients with a tricuspid aortic valve (TAV) undergoing isolated aortic valve surgery before May 2016...
January 15, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29345963/deletion-of-estrogen-receptor-alpha-in-skeletal-muscle-results-in-impaired-contractility-in-female-mice
#2
Brittany C Collins, Tara L Mader, Christine A Cabelka, Melissa R Iñigo, Espen E Spangenburg, Dawn A Lowe
Estradiol deficiency in females can result in skeletal muscle strength loss, and treatment with estradiol mitigates the loss. There are three primary estrogen receptors and estradiol elicits effects through these receptors in various tissues. Ubiquitous estrogen receptor α (ERα) knockout mice exhibit numerous biological disorders, but little is known regarding the specific role of ERα in skeletal muscle contractile function. The purpose of this study was to determine the impact of skeletal muscle specific ERα deletion on contractile function, hypothesizing that ERα is a main receptor through which estradiol affects muscle strength in females...
January 18, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29344331/the-peripheral-flicker-illusion
#3
Hiroyuki Ito, Tomomi Koizumi
A new illusion is reported. A visual object suddenly appearing on a red background sometimes causes an impression of flicker or double flash. In Experiment 1, a red, green, or blue object was presented on a red, green, blue, or gray background. Participants evaluated the illusion strength in reference to the physical flicker of a gray object presented in central vision. The results show that the green or blue object presented on the red background caused the illusion. In Experiment 2, the effect of retinal eccentricity on the illusion was tested...
November 2017: I-Perception
https://www.readbyqxmd.com/read/29343862/angiotensin-ii-overstimulation-leads-to-an-increased-susceptibility-to-dilated-cardiomyopathy-and-higher-mortality-in-female-mice
#4
Sophie Mathieu, Nabil El Khoury, Katy Rivard, Pierre Paradis, Mona Nemer, Céline Fiset
Heart failure (HF) is associated with high mortality and affects men and women differently. The underlying mechanisms for these sex-related differences remain largely unexplored. Accordingly, using mice with cardiac-specific overexpression of the angiotensin II (ANGII) type 1 receptor (AT1R), we explored male-female differences in the manifestations of hypertrophy and HF. AT1R mice of both sexes feature electrical and Ca2+ handling alterations, systolic dysfunction, hypertrophy and develop HF. However, females had much higher mortality (21...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29339993/functional-and-muscle-size-effects-of-flywheel-resistance-training-with-eccentric-overload-in-professional-handball-players
#5
Sergio Maroto-Izquierdo, David García-López, José A de Paz
The aim of the study was to analyse the effects of 6 week (15 sessions) flywheel resistance training with eccentric-overload (FRTEO) on different functional and anatomical variables in professional handball players. Twenty-nine athletes were recruited and randomly divided into two groups. The experimental group (EXP, n = 15) carried out 15 sessions of FRTEO in the leg-press exercise, with 4 sets of 7 repetitions at a maximum-concentric effort. The control group (CON, n = 14) performed the same number of training sessions including 4 sets of 7 maximum repetitions (7RM) using a weight-stack leg-press machine...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29339983/analysis-of-the-hamstring-muscle-activation-during-two-injury-prevention-exercises
#6
Alireza Monajati, Eneko Larumbe-Zabala, Mark Goss-Sampson, Fernando Naclerio
The aim of this study was to perform an electromyographic and kinetic comparison of two commonly used hamstring eccentric strengthening exercises: Nordic Curl and Ball Leg Curl. After determining the maximum isometric voluntary contraction of the knee flexors, ten female athletes performed 3 repetitions of both the Nordic Curl and Ball Leg Curl, while knee angular displacement and electromyografic activity of the biceps femoris and semitendinosus were monitored. No significant differences were found between biceps femoris and semitendinosus activation in both the Nordic Curl and Ball Leg Curl...
December 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29338824/effects-of-preoperative-isokinetic-eccentric-training-and-whey-protein-isolate-supplement-on-quadriceps-strength-and-knee-function-in-patients-with-anterior-cruciate-ligament-rupture
#7
Xiao Yuan Zhang, Hong Shi Huang, Jie Yang, Yuan Yuan Yu, Dong Xia Zhang, Cui Qing Chang
Objective To explore the effect of preoperative isokinetic eccentric training with or not whey protein isolate supplement before operation on lower limb muscle strength and knee function in patients with anterior cruciate ligament (ACL) rupture. Methods A total of 22 male volunteers aged 18-40 years with ACL rupture were recruited in outpatient service. With randomized block design,subjects were randomly assigned to isokinetic eccentric training (IE) group and isokinetic eccentric training with whey protein isolate supplement (IE+WPI) group...
December 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29338027/distribution-of-cone-density-spacing-and-arrangement-in-adult-healthy-retinas-with-adaptive-optics-flood-illumination
#8
Richard Legras, Alain Gaudric, Kelly Woog
The aim of this article is to analyse cone density, spacing and arrangement using an adaptive optics flood illumination retina camera (rtx1™) on a healthy population. Cone density, cone spacing and packing arrangements were measured on the right retinas of 109 subjects at 2°, 3°, 4°, 5° and 6° of eccentricity along 4 meridians. The effects of eccentricity, meridian, axial length, spherical equivalent, gender and age were evaluated. Cone density decreased on average from 28 884 ± 3 692 cones/mm2, at 2° of eccentricity, to 15 843 ± 1 598 cones/mm2 at 6°...
2018: PloS One
https://www.readbyqxmd.com/read/29335098/factors-affecting-corneal-incision-position-during-femtosecond-laser-assisted-cataract-surgery
#9
Chandra Bala, Thomas Chan, Kerrie Meades
PURPOSE: To compare the expected versus actual position and dimension of corneal incisions during femtosecond laser-assisted cataract surgery. SETTING: Private Ophthalmic Clinic, Sydney, NSW, Australia. DESIGN: Retrospective case series. METHODS: Video recordings of femtosecond laser-assisted cataract surgery with a Lensx laser were reviewed. The deviation of the main and 2 secondary incisions from the expected position were correlated with globe tilt, globe displacement, and biometric data...
December 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29333946/does-inside-passing-contribute-to-the-high-incidence-of-groin-injuries-in-soccer-a-biomechanical-analysis
#10
Thomas Dupré, Johannes Funken, Ralf Müller, Kristian R L Mortensen, Filip Gertz Lysdal, Markus Braun, Hartmut Krahl, Wolfgang Potthast
Groin injuries are common in soccer and often cause time-loss from training. While groin injuries have been linked to full effort kicking, the role of inside passing is unclear. Therefore, the purpose of this study was to investigate hip joint kinematics and muscle force, stress and contraction velocity for adductor longus and gracilis during inside passing. 3D kinematics of ten soccer players (23.4 yrs; 77.5 kg; 1.81 m) were captured with a motion capture system inside a Footbonaut. Muscle force and contraction velocity were determined with AnyBody Modelling System...
January 15, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29333219/clinical-utility-of-echocardiography-for-early-and-late-pulmonary-hypertension-in-preterm-infants-relation-with-bronchopulmonary-dysplasia
#11
Yo Han Seo, Hee Joung Choi
Background: We evaluated early and late pulmonary hypertension (PH) in preterm infants and its relation with bronchopulmonary dysplasia (BPD). Methods: Sixty-seven preterm infants < 30 weeks' gestation underwent echocardiography within 14 days after birth for early PH and over 28 days after birth for late PH. We measured tricuspid regurgitation (TR) peak velocity, pulse Doppler-derived myocardial performance index (MPI) of right ventricle (RV) (RV MPI), eccentricity index (EI), and tricuspid annular plane systolic excursion (TAPSE)...
December 2017: Journal of Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/29332122/quantitative-study-of-the-macular-microvasculature-in-human-donor-eyes
#12
Paula K Yu, Zaid Mammo, Chandrakumar Balaratnasingam, Dao-Yi Yu
Purpose: To precisely quantify the macular microvasculature density using microperfusion and labeling techniques in human donor eyes. Such information may be useful in understanding the role of the macular microvasculature in coping with the metabolic requirements of the neurons in this densely packed region, and provide a reference point for clinical studies using recently developed optical imaging techniques. Methods: The macular microvasculature was perfusion-labeled in 18 human donor eyes and optical stacks collected from regions superior, temporal, inferior, and nasal to the foveola using confocal microscopy...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29331157/eccentric-placentae-have-reduced-surface-area-and-are-associated-with-lower-birth-weight-in-babies-small-for-gestational-age
#13
G Ravikumar, J Crasta, J S Prabhu, T Thomas, P Dwarkanath, A Thomas, T S Sridhar, A V Kurpad
Placental structure and function determine birth outcomes. Placental mass does not always correlate with fetal birth weight (BW) in uncomplicated pregnancies which raises the possibility of other variables such as placental shape and cord insertion being the determinants of placental efficiency. In total, 160 women with singleton pregnancy, recruited into a pregnancy cohort were studied. Placental weight (PW) was measured and other data were obtained from clinical records. Birth outcomes were classified as small for gestational age (SGA) and appropriate for gestational age (AGA) based on fetal gender, gestational age (GA) and BW...
January 14, 2018: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/29331044/journey-of-oocyte-from-metaphase-i-to-metaphase-ii-stage-in-mammals
#14
Alka Sharma, Meenakshi Tiwari, Anumegha Gupta, Ashutosh N Pandey, Pramod K Yadav, Shail K Chaube
In mammals, journey from metaphase-I (M-I) to metaphase-II (M-II) is important since oocyte extrude first polar body (PB-I) and gets converted into haploid gamete. The molecular and cellular changes associated with meiotic cell cycle progression from M-I to M-II stage and extrusion of PB-I remain ill understood. Several factors drive oocyte meiosis from M-I to M-II stage. The mitogen-activated protein kinase3/1 (MAPK3/1), signal molecules and Rho family GTPases act through various pathways to drive cell cycle progression from M-I to M-II stage...
January 13, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29330497/visual-learning-with-reduced-adaptation-is-eccentricity-specific
#15
Hila Harris, Dov Sagi
Visual learning is known to be specific to the trained target location, showing little transfer to untrained locations. Recently, learning was shown to transfer across equal-eccentricity retinal-locations when sensory adaptation due to repetitive stimulation was minimized. It was suggested that learning transfers to previously untrained locations when the learned representation is location invariant, with sensory adaptation introducing location-dependent representations, thus preventing transfer. Spatial invariance may also fail when the trained and tested locations are at different distance from the center of gaze (different retinal eccentricities), due to differences in the corresponding low-level cortical representations (e...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29329890/pain-motion-and-function-comparison-of-two-exercise-protocols-for-the-rotator-cuff-and-scapular-stabilizers-in-patients-with-subacromial-syndrome
#16
Eva Vallés-Carrascosa, Tomás Gallego-Izquierdo, José Jesús Jiménez-Rejano, Gustavo Plaza-Manzano, Daniel Pecos-Martín, Fidel Hita-Contreras, Alexander Achalandabaso Ochoa
STUDY DESIGN: Randomized clinical trial. INTRODUCTION: Eccentric exercise (EE) was shown to be an effective treatment in tendinopathies. However, the evidence of its effectiveness in subacromial syndrome (SS) is scarce. Moreover, consensus has not been reached on whether best results for SS are obtained by means of EE with or without pain. PURPOSE OF THE STUDY: The purpose of this is to compare the effect on pain, active range of motion (AROM), and shoulder function of an exercise protocol performed with pain <40 mm Visual Analog Scale (VAS) and without pain, in patients with SS...
January 9, 2018: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/29329131/alk-gene-fusions-in-epithelioid-fibrous-histiocytoma-a-study-of-14-cases-with-new-histopathological-findings
#17
Dmitry V Kazakov, Liubov Kyrpychova, Petr Martinek, Petr Grossmann, Petr Steiner, Tomas Vanecek, Michal Pavlovsky, Vladimir Bencik, Michael Michal, Michal Michal
Previous studies showed that ALK is often positive in epithelioid fibrous histiocytoma (EFH). Two cases of EFH with ALK gene fusions have been recorded. Our objective was to study a series of EFH to present histopathological variations of EFH, identify novel ALK gene fusions, and determine whether there is a correlation between histopathological features and particular gene. We investigated 14 cases of EFH, all ALK immunopositive. The cases were assessed histopathologically as well as for ALK and TFE-3 rearrangements using FISH and ALK gene fusions using next-generation sequencing...
January 11, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29327824/are-there-bilateral-isokinetic-shoulder-rotator-differences-in-basketball-male-players
#18
Thierry Weissland, Maryne Cozette, Clare Doyle, Antoine Gabrion
BACKGROUND: The internal (IR) and external (ER) rotator shoulder strength are often assess in the upper limb sports to prevent a risk of injuries. The purpose of this comparative study was to measure the agonist/antagonist balance of shoulder strength and to determine whether significant differences exist between the dominant and nondominant sides in basketball players compared to a control groups. METHODS: During the championship, 23 elite male-basketball players (BB) and 23 healthy males (CG) were tested bilaterally on a Cybex Norm isokinetic dynamometer in a seated position with 45° shoulder abduction in the scapular plane at 60°...
January 10, 2018: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29327439/the-hidden-concealed-left-sided-accessory-pathway-an-uncommon-cause-of-svt-in-young-people
#19
Robert H Pass, Leonardo Liberman, Eric S Silver, Christopher M Janson, Andrew D Blaufox, Lynn Nappo, Scott R Ceresnak
BACKGROUND: Concealed left sided accessory pathways (CLAP) are a cause of SVT in the young. Most are mapped with RV apical/outflow pacing. Rarely, alternative means of mapping are required. We review our experience from 3 pediatric EP centers with a rare form of "hidden" CLAP. METHODS: All patients < 21 years undergoing EP study from 2008-2014 with a "hidden" CLAP (defined as an accessory pathway (AP) for which RV pacing at CL's stable for mapping did not demonstrate eccentric retrograde conduction) were included...
January 12, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29326905/neuromuscular-features-in-sprinters-with-cerebral-palsy-case-studies-based-on-paralympic-classification
#20
Diego Antunes, Mateus Rossato, Rafael Lima Kons, Raphael Luiz Sakugawa, Gabriela Fischer
Despite the evolution of runner performance in athletes with cerebral palsy (CP), little is known about neuromuscular parameters of sprinters from different classes, especially related to power output, muscular imbalances and asymmetry indexes in lower limbs. The aim of this study was to assess muscle power, muscular imbalance and asymmetry in sprinters with CP. Four male sprinters with CP (age, 18 to 27 years; body mass, 58.5 to 72.8 kg; height, 161.5 to 174 cm) classified as T38, T37, T36, T35 according to International Paralympic Committee functional classification, performed vertical counter movement jump and squat jump on force plate and isokinetic torque evaluations in both limbs...
December 2017: Journal of Exercise Rehabilitation
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