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https://www.readbyqxmd.com/read/28676238/port-catheter-associated-aureobasidium-melanigenum-fungemia
#1
Shih-Chung Wang, Hsiu-Jung Lo, Li-Jhen Lin, Chang-Hua Chen
No abstract text is available yet for this article.
July 1, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28672927/fungal-chorioretinitis-with-systemic-candidiasis-in-an-infant-following-treatment-with-broad-spectrum-antibiotics-a-case-report
#2
Cheng-Wei Lu, Yuan Tao, Xiao-Hong Li, Yu Dong, Dan-Dan Zhou
Fungal chorioretinitis is a rare complication of neonatal fungemia that may lead to vision loss. Early diagnosis and aggressive treatment are essential to avoid vision loss. This study describes a case of a full term infant with candidiasis infection, which disseminated from the eye to the hip joint, and the diagnosis and treatment of fungal chorioretinitis and hip osteoarthritis with systemic candidiasis. The current case report indicates that the duration of therapy for fungal chorioretinitis should be at least 4-6 weeks long and should ideally continue until all clinical evidence of intraocular infection has been resolved...
July 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28669678/virulence-and-antifungal-therapy-of-murine-disseminated-infection-by-rhodotorula-mucilaginosa
#3
Pamela Thomson, Loida López-Fernández, Josep Guarro, Javier Capilla
Rhodotorula infections have emerged in recent years causing mainly fungemia associated to high mortality. We have evaluated the in vitro activity of nine antifungal drugs against four clinical strains of Rhodotorula mucilaginosa, being amphotericin B, voriconazole and posaconazole the most active compounds. The experimental virulence of this fungus and the efficacy of the three mentioned drugs were evaluated in disseminated infections in neutropenic mice. Infection resulted in a high fungal load in all the organs studied without evident particular tropism...
June 16, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28662024/fungemia-associated-with-schizophyllum-commune-in-brazil
#4
Manoel Marques Evangelista Oliveira, Alberto Santos Lemos, Marcelo Luiz Carvalho Gonçalves, Rodrigo Almeida-Paes, Vitor Ribeiro Gomes de Almeida Valviesse, José Alfredo Moreira, Marco Antônio Sales Dantas Lima, Eleonora Carregal, Maria Clara Gutierrez Galhardo, Cristiane da Cruz Lamas, Rosely Maria Zancopé Oliveira
No abstract text is available yet for this article.
June 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28652824/fungal-endophthalmitis-in-an-elderly-woman-differing-responses-in-each-eye
#5
Rei Sakata, Jiro Numaga
Candida endophthalmitis is caused by hematogenous metastasis of the yeast. To ensure early diagnosis, serodiagnosis, or surveillance culturing is usually performed. If fungemia is apparent upon successive serological testing (in at least two tests: blood culture and/or measurement of β-d-glucan level), ophthalmic consultation is necessary, even if no ophthalmic complaint is evident. This is because early detection with prompt prescription of systemic antifungal agents inhibits progression of the distinctive cholioretinitis...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28652216/fungemia-and-necrotic-lymph-node-infection-with-sporopachydermia-cereana-in-a-patient-with-acute-myeloid-leukemia
#6
Craig Kingston, Michael Medinger, Florian Banderet-Uglioni, Stefano Bassetti, Mario Bargetzi, Sebastian Haubitz, Christoph A Fux, Veronika Bättig, Daniel Goldenberger, Jakob Passweg, Marc Heizmann
Sporopachydermia cereana is a rare yeast found in necrotic cactus tissue, predominantly in the Americas. Infection in humans with clinical data has only been reported in four patients so far, all of whom died, either directly from the pathogen or from other complications of immunosuppression. Treatment of the yeast is complicated by difficulties in identification of the pathogen with conventional diagnostic techniques and by intrinsic resistance to echinocandins. The first patient to survive a disseminated infection with S...
June 23, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28625838/comparison-of-time-to-detection-values-between-bact-alert-virtuo-and-bact-alert-3d-instruments-for-clinical-blood-culture-samples
#7
Francesco Congestrì, Maria Federica Pedna, Michela Fantini, Michela Samuelli, Pasqua Schiavone, Arianna Torri, Stefania Bertini, Vittorio Sambri
OBJECTIVES: The early detection of bacteraemia and fungemia is of paramount importance to guide antimicrobial therapy in septic patients. In this study the 'time to detection' (TTD) value for the new blood culture system BacT/ALERT VIRTUO (VIRTUO) was evaluated in 1462 positive clinical bottles and compared with the TTD for 1601 positive clinical bottles incubated in the BacT/ALERT 3D system (BTA-3D). METHODS: The most representative microorganisms isolated from bottles incubated in both blood culture systems were divided into eight categories (in order of frequency): coagulase-negative staphylococci (CoNS), Escherichia coli, Enterobacteriaceae (other than E...
June 15, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28625801/clinical-features-antifungal-susceptibility-and-outcome-of-candida-guilliermondii-fungemia-an-experience-in-a-tertiary-hospital-in-mid-taiwan
#8
Ting-Yu Tseng, Tsung-Chia Chen, Cheng-Mao Ho, Po-Chang Lin, Chia-Huei Chou, Chia-Ta Tsai, Jen-Hsien Wang, Chih-Yu Chi, Mao-Wang Ho
BACKGROUNDS: Candida guilliermondii is rarely isolated from clinical specimen. C. guilliermondii fungemia is seldom reported in the literature. The aims of this study were to report the clinical features, antifungal susceptibility, and outcomes of patients with C. guilliermondii fungemia. METHODS: From 2003 to 2015, we retrospectively analyzed the clinical and laboratory data of patients with C. guilliermondii fungemia in a tertiary hospital in mid-Taiwan. We performed a multivariable logistic regression analysis to identify the risk factors of mortality...
May 17, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28622982/comparison-of-the-vitek-2-antifungal-susceptibility-system-with-etest-using-clinical-isolates-of-candida-species
#9
Wadha Alfouzan, Tahani Al-Enezi, Ebteehal AlRoomi, Vayalil Sandhya, Rachel Chandy, Zia Uddin Khan
BACKGROUND: Candida species are part of the normal human microbiota. However, in recent years, nosocomial bloodstream Candida infections have emerged as a significant problem ranking the fourth common cause of fungemia in intensive care units. Although microdilution methods are the ones recommended for susceptibility testing, they are difficult to undertake in the clinical practice. Thus, an automated commercially available test is ideal. AIMS: To compare minimum inhibitory concentrations (MICs) obtained with the recently introduced Vitek 2 yeast susceptibility system card (AST-YS01) with Etest...
June 13, 2017: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/28597394/invasive-candidiasis-in-brescia-italy-analysis-of-species-distribution-and-antifungal-susceptibilities-during-seven-years
#10
M A De Francesco, G Piccinelli, M Gelmi, F Gargiulo, G Ravizzola, G Pinsi, L Peroni, C Bonfanti, A Caruso
The aims of this study were to evaluate the epidemiology of nosocomial candidemia in a large teaching hospital in Brescia, Italy, and the in vitro antifungal susceptibility of isolates. We analyzed 196 isolates causing fungemia in patients admitted in our hospital, between January 2009 and December 2015. Strains were identified by VITEK 2 and MALDI-TOF MS. MICs were determined by Sensititre Yeast OneTM. The resistance was defined by using the revised CLSI breakpoints/epidemiological cutoff values to assign susceptibility or wild type to systemic antifungal agents...
June 8, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28584138/initial-treatment-of-cancer-patients-with-fluconazole-susceptible-dose-dependent-candida-glabrata-fungemia-better-outcome-with-an-echinocandin-or-polyene-compared-to-an-azole
#11
Audrey Le, Dimitrios Farmakiotis, Jeffrey J Tarrand, Dimitrios P Kontoyiannis
28-day crude mortality in 68 cancer patients with fluconazole susceptible dose-dependent Candida glabrata fungemia started on treatment (within 48 hours after blood culture collection) with an echinocandin or liposomal amphotericin-B was better (30%), compared to those treated with azole monotherapy (52%, p=0.07). After adjusting for confounders, azole monotherapy was associated with worse 28-day survival (hazard ratio 3.8, p=0.003).
June 5, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28574735/fatal-course-of-saprochaete-capitata-fungemia-in-children-with-acute-lymphoblastic-leukemia
#12
Zeynep Canan Özdemir, Ayşe Bozkurt Turhan, Yeter Düzenli Kar, Çağrı Ener Dinleyici, Özcan Bör
Saprochaete capitata (S. capitata) is a very rare fungal pathogen that causes disseminated opportunistic infections in patients with hematologic malignancies. Fever resistant to broad-spectrum antibiotic and antifungal treatment is common in the presence of fungemia during the period of profound neutropenia. We describe three cases of leukemic children who died from S. capitata fungemia following a first febrile neutropenic episode after the induction of chemotherapy. S. capitata fungemia is an emergent infection associated with high mortality and low susceptibility to fluconazole and echinocandins...
June 2, 2017: Pediatric Hematology and Oncology
https://www.readbyqxmd.com/read/28539343/multicenter-clinical-evaluation-of-bact-alert-virtuo-blood-culture-system
#13
Michael R Jacobs, Tony Mazzulli, Kevin C Hazen, Caryn E Good, Ayman M Abdelhamed, Pauline Lo, Bianche Shum, Katharine P Roman, Danielle C Robinson
Background: The BacT/ALERT VIRTUO is an advanced, automated blood culture system incorporating improved automation and an enhanced detection algorithm to shorten time to detection.Methods: Multicenter study of the investigational VIRTUO system (bioMérieux, Inc., Durham, NC) compared to BacT/ALERT 3D (BTA3D) for detection of bacteremia/fungemia in four bottle types, SA and FA Plus (aerobic) and SN and FN Plus (anaerobic) in a clinical setting with patient samples, in a matched system design clinical trial. Blood was added to paired aerobic or anaerobic bottles, with volume in each bottle pair required to be ≤10 mL per bottle and within 30% of each other...
May 24, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28502948/disseminated-cryptococcosis-with-adrenal-insufficiency-and-meningitis-in-an-immunocompetent-individual
#14
Misa Ito, Takashi Hinata, Kaku Tamura, Ayano Koga, Toshimitsu Ito, Hiroko Fujii, Fumihiko Hirata, Hidenari Sakuta
We present a case of cryptococcosis with adrenal insufficiency and meningitis in a healthy host without any risk factors. Antifungal therapy did not reduce the cryptococcal antigen titers of the cerebrospinal fluid and serum or the bilateral adrenal gland enlargement. It was suggested that the adrenal glands were the focus of persistent fungemia. Removal of both adrenal glands brought about a response to antifungal therapy. We conclude that if antifungal therapy is ineffective, bilateral adrenalectomy is an effective measure for treatment of such patients...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28486866/the-predictive-value-of-coefficient-of-pct-%C3%A3-bg-for-anastomotic-leak-in-esophageal-carcinoma-patients-with-ards-after-esophagectomy
#15
Huan Li, Daofeng Wang, Wenxiao Wei, Lamei Ouyang, Ning Lou
Anastomotic leak was a potentially severe life-threatening complication of esophagectomy, which drew attention in consequence of progressive dyspnea until acute respiratory distress syndrome (ARDS) due to the early asymptomatic presentation. Respiratory failure, caused by ARDS as the severe presentation of anastomotic leak, is the most common organ failure. CRP (C-reactive protein), procalcitonin (PCT), and Blood G (BG) test are the sensitivity markers for inflammatory, sepsis, and fungemia, respectively. Early recognition and intervention treatment of anastomotic leak may alleviate complication and improve outcome...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28423088/the-epidemiology-of-cryptococcosis-and-the-characterization-of-cryptococcus-neoformans-isolated-in-a-brazilian-university-hospital
#16
Paula Augusta Dias Fogaça de Aguiar, Reginaldo Dos Santos Pedroso, Aércio Sebastião Borges, Tomaz de Aquino Moreira, Lúcio Borges de Araújo, Denise Von Dolinger de Brito Röder
Cryptococcosis, a systemic disease caused by the fungus Cryptococcus neoformans/ Cryptococcus gattii is more severe in immunocompromised individuals. This study aimed to analyze the epidemiology of the disease, the molecular characteristics and the antifungal susceptibility of C. neoformans isolated from patients treated in a Brazilian university hospital. This retrospective study was conducted in the Clinical Hospital, Federal University of Uberlândia, and evaluated cases of cryptococcosis and strains of C...
April 13, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28414678/what-the-eyes-don-t-see-the-heart-does-grieve-over
#17
M Sciaudone, M Dery
INTRODUCTION: A 71 year old Peruvian woman presented with blurry vision and bilateral eye pain and had evidence of bilateral endophthalmitis on eye examination. Her past medical history was notable for multiple abdominal surgeries within the preceding months, including an incarcerated inguinal hernia repair which required an ileostomy placement, and cholecystitis requiring cholecystostomy tube placement. Over her multiple long hospitalizations, she developed bacteremia and fungemia on several occasions, with organisms including Enterobacter cloacae, Klebsiella pneumoniae, Bacteroides fragilis, Pseudomonas aeruginosa, Enterococcus faecium, and Candida albicans...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28409093/first-case-of-invasive-magnusiomyces-capitatus-infection-in-slovakia
#18
Dominika Tanuskova, Julia Horakova, Peter Svec, Ivana Bodova, Martina Lengerova, Matej Bezdicek, Miroslava Poczova, Jozef Koppl, Alexandra Kolenova
Magnusiomyces capitatus (previously known as Geotrichum capitatum or Blastoschizomyces capitatus or Trichosporon capitatum) is a rare cause of fungal infection in immunocompromised patients. Most of these cases (87%) have been reported from the Mediterranean region, as it is extremely rare to recognize it in other regions. Here we report a first case of disseminated M. capitatus infection in Slovakia. The patient - 19 year old woman with myelodysplastic syndrome was diagnosed with M. capitatus fungemia after allogeneic stem cell transplantation...
June 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28393434/multivisceral-transplantation-for-abdominal-tumors-in-children-a-single-center-experience-and-review-of-the-literature
#19
Eliza Lee, Nicole Hodgkinson, Rima Fawaz, Khashayar Vakili, Heung Bae Kim
Standard management of intra-abdominal pediatric solid tumors requires complete resection. However, tumors with multiple organ and vascular involvement present a unique surgical challenge. We conducted a retrospective chart review of four patients, aged 2-14 years, undergoing MVT for intra-abdominal tumors with significant involvement of the visceral arteries and/or portomesenteric venous system at our institution. Indications for MVT included hepatocellular carcinoma, inflammatory myofibroblastic tumor, and two cases of hepatoblastoma...
August 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28377868/a-case-of-breakthrough-candida-parapsilosis-fungemia-during-micafungin-therapy-for-a-candida-glabrata-bloodstream-infection
#20
Yuta Norimatsu, Daiichi Morii, Asako Kogure, Taeko Hamanaka, Yoshihiro Kuwano, Takayuki Yokozawa, Toshimi Oda
We describe a case of breakthrough Candida parapsilosis fungemia in an 80-year-old woman with pyoderma gangrenosum and rheumatoid arthritis. C. parapsilosis was detected in blood culture while the patient was treated with micafungin for a Candida glabrata bloodstream infection. The breakthrough infection was successfully treated with liposomal amphotericin B.
June 2017: Medical Mycology Case Reports
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